Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	-	MUS81 FANCM	2.82e-04	3	182	2	3.40.50.10130
Domain	CSRNP_N	CSRNP2 CSRNP3	2.82e-04	3	182	2	IPR031972
Domain	DNA_repair_nuc_XPF/helicase	MUS81 FANCM	2.82e-04	3	182	2	IPR020819
Domain	Cys/Ser-rich_nuc_prot	CSRNP2 CSRNP3	2.82e-04	3	182	2	IPR023260
Domain	CSRNP_N	CSRNP2 CSRNP3	2.82e-04	3	182	2	PF16019
Domain	Glyco_hormone_CN	CGB3 CGB1 MUC5AC	3.80e-04	15	182	3	IPR006208
Domain	Cys_knot	CGB3 CGB1 MUC5AC	3.80e-04	15	182	3	PF00007
Domain	Ig_I-set	SEMA3C L1CAM SIGLEC14 IGSF10 LRIG3 SIGLEC7 MYPN MDGA1	5.61e-04	190	182	8	IPR013098
Domain	I-set	SEMA3C L1CAM SIGLEC14 IGSF10 LRIG3 SIGLEC7 MYPN MDGA1	5.61e-04	190	182	8	PF07679
Domain	HTH_motif	HHEX CDX4 HOXA2 LBX1 BARHL2	5.64e-04	69	182	5	IPR000047
Domain	Laminin_G_2	COL11A1 FAT3 SLIT2 CNTNAP4	6.06e-04	40	182	4	PF02210
Domain	Helicase_C	ERCC6L DDX51 FANCM DDX50 ASCC3 DHX34	6.31e-04	107	182	6	PF00271
Domain	HELICc	ERCC6L DDX51 FANCM DDX50 ASCC3 DHX34	6.31e-04	107	182	6	SM00490
Domain	Helicase_C	ERCC6L DDX51 FANCM DDX50 ASCC3 DHX34	6.63e-04	108	182	6	IPR001650
Domain	CTCK_1	MUC19 SLIT2 MUC5AC	6.67e-04	18	182	3	PS01185
Domain	HELICASE_CTER	ERCC6L DDX51 FANCM DDX50 ASCC3 DHX34	6.96e-04	109	182	6	PS51194
Domain	HELICASE_ATP_BIND_1	ERCC6L DDX51 FANCM DDX50 ASCC3 DHX34	6.96e-04	109	182	6	PS51192
Domain	DEXDc	ERCC6L DDX51 FANCM DDX50 ASCC3 DHX34	6.96e-04	109	182	6	SM00487
Domain	Helicase_ATP-bd	ERCC6L DDX51 FANCM DDX50 ASCC3 DHX34	7.31e-04	110	182	6	IPR014001
Domain	DEAD/DEAH_box_helicase_dom	DDX51 FANCM DDX50 ASCC3 DHX34	7.31e-04	73	182	5	IPR011545
Domain	DEAD	DDX51 FANCM DDX50 ASCC3 DHX34	7.31e-04	73	182	5	PF00270
Domain	LamG	COL11A1 FAT3 SLIT2 CNTNAP4	8.74e-04	44	182	4	SM00282
Domain	Restrct_endonuc-II-like	MUS81 FANCM	9.26e-04	5	182	2	IPR011335
Domain	ERCC4	MUS81 FANCM	9.26e-04	5	182	2	SM00891
Domain	PLPL	PNPLA2 PNPLA5	9.26e-04	5	182	2	IPR033562
Domain	ERCC4_domain	MUS81 FANCM	9.26e-04	5	182	2	IPR006166
Domain	ERCC4	MUS81 FANCM	9.26e-04	5	182	2	PF02732
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FAM193B PNPLA2 RIN3 TBC1D9B CDC42BPA ACACA L1CAM ADGRB2 TRMT1 MUS81 C15orf39 ZNF395 ZZEF1 AHDC1 SBNO2 TBC1D24 NCOR1 TMEM129 SCAP IER5L KBTBD11 NINL AKAP13 TANC1 WDFY3 DHX34 MED13	5.07e-11	1105	186	27	35748872
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	USP53 PRUNE2 CDC42BPA ACACA TRIOBP EVC DGKH AHDC1 SBNO2 TASOR2 EEF1A2 CCNG2 YEATS2 NLGN3 FAM120C SETBP1 ARID5B KNDC1 NUMB AKAP13 PISD TANC1 ANKRD12 NOTCH3 MOCOS ZC3HAV1	1.17e-07	1489	186	26	28611215
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP53 CDC42BPA TRIOBP ZZEF1 TBC1D24 LRIG3 UBXN4 SETBP1 KBTBD11 MED12L NINL SENP6 DHX34 ANKS3 MED13	1.94e-07	529	186	15	14621295
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	USP53 JCAD CDC42BPA ACACA ERCC6L EXPH5 RAB11FIP2 CKAP5 MPDZ RGS12 EEF1A2 VPS13D MTMR4 NUMB AKAP13 TANC1 BICC1 ZC3HAV1	9.94e-07	861	186	18	36931259
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	FAM193B ACACA MPDZ ZDBF2 VPS13D UBR5 MYPN TANC1 ASCC3	2.07e-06	209	186	9	36779422
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	USP53 PRUNE2 JCAD CCPG1 INPP5D TASOR2 NCOR1 EGR1 SETBP1 NUMB AKAP13 DNMT3B	3.94e-06	430	186	12	35044719
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ACACA ERCC6L CKAP5 DDX51 TSSC4 C2CD5 YEATS2 NCOR1 SETD2 MSL3 ZBTB40 SENP6 TACC3 MED13 MOCOS ZC3HAV1	4.70e-06	774	186	16	15302935
Pubmed	A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.	SEMA3C L1CAM NCOR1 SETBP1 MARCKS	8.79e-06	52	186	5	15328020
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ACACA CKAP5 RUSC1 C15orf39 ZDBF2 YEATS2 NCOR1 UBR5 ARID5B TACC3 ASCC3	1.73e-05	418	186	11	34709266
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CUL1 E2F7 C15orf39 E2F2 ZDBF2 YEATS2 ZC3H7A NCOR1 SETD2 UBR5 ARID5B SENP6 TANC1	1.88e-05	588	186	13	38580884
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	INTS7 ZDBF2 NCOR1 SETD2 UBR5 ARID5B MSL3 MAGEC1 ASCC3	2.30e-05	282	186	9	23667531
Pubmed	Notch3 promotes prostate cancer-induced bone lesion development via MMP-3.	MMP3 NOTCH3	2.84e-05	2	186	2	31467432
Pubmed	Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.	TTYH1 DNMT3B	2.84e-05	2	186	2	24316981
Pubmed	Notch3 signaling is associated with MUC5AC expression and favorable prognosis in patients with small intestinal adenocarcinomas.	MUC5AC NOTCH3	2.84e-05	2	186	2	24810798
Pubmed	SNX16 activates c-Myc signaling by inhibiting ubiquitin-mediated proteasomal degradation of eEF1A2 in colorectal cancer development.	SNX16 EEF1A2	2.84e-05	2	186	2	31876369
Pubmed	Matrix metalloproteinases contribute to the regulation of chemokine expression and pulmonary inflammation in Cryptococcus infection.	MMP3 MMP12	2.84e-05	2	186	2	26445891
Pubmed	ANK2 autism mutation targeting giant ankyrin-B promotes axon branching and ectopic connectivity.	ANK2 L1CAM	2.84e-05	2	186	2	31285321
Pubmed	Early elevation of serum MMP-3 and MMP-12 predicts protection from World Trade Center-lung injury in New York City Firefighters: a nested case-control study.	MMP3 MMP12	2.84e-05	2	186	2	24146820
Pubmed	Imbalanced MMP-3 and MMP-12 serum levels in systemic lupus erythematosus patients with Jaccoud's arthropathy and a distinctive MRI pattern.	MMP3 MMP12	2.84e-05	2	186	2	33404658
Pubmed	Genetic variation in the matrix metalloproteinase genes and diabetic nephropathy in type 1 diabetes.	MMP3 MMP12	2.84e-05	2	186	2	21277817
Pubmed	Role of neuropsin in formation and maturation of Schaffer-collateral L1cam-immunoreactive synaptic boutons.	L1CAM KLK8	2.84e-05	2	186	2	16537644
Pubmed	Blocking Notch3 Signaling Abolishes MUC5AC Production in Airway Epithelial Cells from Individuals with Asthma.	MUC5AC NOTCH3	2.84e-05	2	186	2	31922915
Pubmed	NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin.	L1CAM KLK8	2.84e-05	2	186	2	12944500
Pubmed	Functional interaction between matrix metalloproteinase-3 and semaphorin-3C during cortical axonal growth and guidance.	SEMA3C MMP3	2.84e-05	2	186	2	17021275
Pubmed	Early growth response factor 1 is essential for cigarette smoke-induced MUC5AC expression in human bronchial epithelial cells.	EGR1 MUC5AC	2.84e-05	2	186	2	28602698
Pubmed	Nervous system defects of AnkyrinB (-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD AnkyrinB in premyelinated axons.	ANK2 L1CAM	2.84e-05	2	186	2	9832558
Pubmed	TACC3-ch-TOG interaction regulates spindle microtubule assembly by controlling centrosomal recruitment of γ-TuRC.	CKAP5 TACC3	2.84e-05	2	186	2	36790370
Pubmed	Male meiotic spindle poles are stabilized by TACC3 and cKAP5/chTOG differently from female meiotic or somatic mitotic spindles in mice.	CKAP5 TACC3	2.84e-05	2	186	2	38413710
Pubmed	L1-dependent neuritogenesis involves ankyrinB that mediates L1-CAM coupling with retrograde actin flow.	ANK2 L1CAM	2.84e-05	2	186	2	14657231
Pubmed	Apparent tradeoff of higher activity in MMP-12 for enhanced stability and flexibility in MMP-3.	MMP3 MMP12	2.84e-05	2	186	2	20655856
Pubmed	A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition.	HHEX NOTCH3	2.84e-05	2	186	2	31843982
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXR1 HHEX CDX4 E2F7 E2F2 ZNF395 HOXA2 YEATS2 SOX7 ZGLP1 LBX1 EGR1 BARHL2 SETBP1 NEUROD6 ST18	3.32e-05	908	186	16	19274049
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FAT3 E2F2 ZZEF1 C2CD5 YEATS2 SLIT2 LRIG3 SETDB2 SETD2 ARHGEF33 LBX1 UBR5 FAM120C TANC1 WDFY3 ASCC3 DHX34 ANKS3	3.38e-05	1116	186	18	31753913
Pubmed	Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.	POT1 SLC44A2 E2F2 TLR9 KCNH6 BCL10 MMP3 MMP12	3.71e-05	231	186	8	21048031
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	FAM193B CDC42BPA ACACA ABCA13 SLIT2 USP51 ASXL3 TENM1 ZBTB40 TNS4 MMP12 DHX34	4.65e-05	552	186	12	10737800
Pubmed	A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2.	TLR9 SETDB2 SPINK5	5.25e-05	14	186	3	20085599
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TBC1D9B ADGRB2 TRIOBP SLC22A17 TASOR2 SLIT2 NLGN3 SETD2 NINL TACC3 ANKS3 NOTCH3	5.34e-05	560	186	12	21653829
Pubmed	MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation.	L1CAM NEUROD6 MARCKS	6.53e-05	15	186	3	29546593
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 FAM193B TBC1D9B EXPH5 FANCM C2CD5 NLGN3 SETD2 VPS13D SCAP CNTNAP4	7.68e-05	493	186	11	15368895
Pubmed	Molecular cloning, characterization and expression of thyroid-stimulating hormone receptor in channel catfish.	CGB3 CGB1	8.50e-05	3	186	2	19523396
Pubmed	Matrix metalloproteinase (MMP)-3 activates MMP-9 mediated vascular smooth muscle cell migration and neointima formation in mice.	MMP3 MMP12	8.50e-05	3	186	2	21719762
Pubmed	Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.	NUMB LNX1	8.50e-05	3	186	2	10551880
Pubmed	Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer.	MMP3 MMP12	8.50e-05	3	186	2	16311244
Pubmed	Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis.	MMP3 MMP12	8.50e-05	3	186	2	19321798
Pubmed	A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells.	CKAP5 TACC3	8.50e-05	3	186	2	20838383
Pubmed	A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian Numb.	NUMB LNX1	8.50e-05	3	186	2	14990566
Pubmed	The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX.	NUMB LNX1	8.50e-05	3	186	2	9535908
Pubmed	Matrix metalloproteinase gene polymorphisms: lack of association with chronic obstructive pulmonary disease in a Brazilian population.	MMP3 MMP12	8.50e-05	3	186	2	19731200
Pubmed	SOX7 inhibits the malignant progression of bladder cancer via the DNMT3B/CYGB axis.	SOX7 DNMT3B	8.50e-05	3	186	2	39227479
Pubmed	Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.	CKAP5 TACC3	8.50e-05	3	186	2	20566684
Pubmed	Bicc1 ribonucleoprotein complexes specifying organ laterality are licensed by ANKS6-induced structural remodeling of associated ANKS3.	ANKS3 BICC1	8.50e-05	3	186	2	37733651
Pubmed	Molecular markers associated with nonepithelial ovarian cancer in formalin-fixed, paraffin-embedded specimens by genome wide expression profiling.	E2F2 EGR1	8.50e-05	3	186	2	22531302
Pubmed	BNIP2 extra long inhibits RhoA and cellular transformation by Lbc RhoGEF via its BCH domain.	PRUNE2 AKAP13	8.50e-05	3	186	2	18445682
Pubmed	Fine-scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissues.	CGB3 CGB1	8.50e-05	3	186	2	18048458
Pubmed	Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome.	ANK2 NEUROD6	8.50e-05	3	186	2	37428632
Pubmed	Association of matrix metalloprotease 1, 3, and 12 polymorphisms with rheumatic heart disease in a Chinese Han population.	MMP3 MMP12	8.50e-05	3	186	2	29458338
Pubmed	Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries.	MMP3 MMP12	8.50e-05	3	186	2	16221765
Pubmed	Novel insights into the expression of CGB1 & 2 genes by epithelial cancer cell lines secreting ectopic free hCGβ.	CGB3 CGB1	8.50e-05	3	186	2	24778026
Pubmed	The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.	CKAP5 TACC3	8.50e-05	3	186	2	24273164
Pubmed	A comparative study of human GS2, its paralogues, and its rat orthologue.	PNPLA2 PNPLA5	8.50e-05	3	186	2	17603008
Pubmed	Induced mRNA expression of matrix metalloproteinases Mmp-3, Mmp-12, and Mmp-13 in the infarct cerebral cortex of photothrombosis model mice.	MMP3 MMP12	8.50e-05	3	186	2	32987131
Pubmed	Matrix metalloprotease polymorphisms are associated with gas transfer in alpha 1 antitrypsin deficiency.	MMP3 MMP12	8.50e-05	3	186	2	19293200
Pubmed	LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation.	NUMB LNX1	8.50e-05	3	186	2	11782429
Pubmed	Fat-specific protein 27 inhibits lipolysis by facilitating the inhibitory effect of transcription factor Egr1 on transcription of adipose triglyceride lipase.	PNPLA2 EGR1	8.50e-05	3	186	2	24742676
Pubmed	Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection.	MMP3 MMP12	8.50e-05	3	186	2	12097550
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	EXPH5 CKAP5 KCNB2 UBXN4 TENM1 NUMB TANC1 ZC3HAV1	9.21e-05	263	186	8	34702444
Pubmed	Armc5 deletion causes developmental defects and compromises T-cell immune responses.	ERCC6L E2F2 ZBTB40	9.68e-05	17	186	3	28169274
Pubmed	PEG3 control on the mammalian MSL complex.	HOXA2 MSL3 ASCC3	1.16e-04	18	186	3	28609438
Pubmed	Polymorphisms in matrix metalloproteinase-1, -3, -9, and -12 genes in relation to subarachnoid hemorrhage.	MMP3 MMP12	1.69e-04	4	186	2	11546917
Pubmed	MMP expression in rheumatoid inflammation: the rs11568818 polymorphism is associated with MMP-7 expression at an extra-articular site.	MMP3 MMP12	1.69e-04	4	186	2	23343931
Pubmed	Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy.	CUL1 FBXO32	1.69e-04	4	186	2	11717410
Pubmed	Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.	MUC5AC NOTCH3	1.69e-04	4	186	2	22691042
Pubmed	CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth.	L1CAM NUMB	1.69e-04	4	186	2	12942088
Pubmed	NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9.	TLR9 NCOR1	1.69e-04	4	186	2	32644192
Pubmed	Association of self-DNA mediated TLR9-related gene, DNA methyltransferase, and cytokeratin protein expression alterations in HT29-cells to DNA fragment length and methylation status.	TLR9 DNMT3B	1.69e-04	4	186	2	24459426
Pubmed	A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.	CKAP5 TACC3	1.69e-04	4	186	2	21297582
Pubmed	Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathway.	PNPLA2 EGR1	1.69e-04	4	186	2	23858058
Pubmed	A polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T-cell activation.	INPP5D LY9	1.69e-04	4	186	2	26221972
Pubmed	Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.	ANK2 L1CAM	1.69e-04	4	186	2	34812142
Pubmed	Impact of viral and host DNA methylations on HPV16-related cervical cancer pathogenesis.	TLR9 DNMT3B	1.69e-04	4	186	2	28459195
Pubmed	Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.	ANKRD13A BCL10	1.69e-04	4	186	2	26038114
Pubmed	Genotype-phenotype analysis of SNPs associated with primary angle closure glaucoma (rs1015213, rs3753841 and rs11024102) and ocular biometry in the EPIC-Norfolk Eye Study.	COL11A1 ST18	1.69e-04	4	186	2	23505305
Pubmed	MicroRNA-155 induction by Mycobacterium bovis BCG enhances ROS production through targeting SHIP1.	INPP5D TLR9	1.69e-04	4	186	2	24937178
Pubmed	Role of MMP-1 (-519A/G, -1607 1G/2G), MMP-3 (Lys45Glu), MMP-7 (-181A/G), and MMP-12 (-82A/G) Variants and Plasma MMP Levels on Obesity-Related Phenotypes and Microvascular Reactivity in a Tunisian Population.	MMP3 MMP12	1.69e-04	4	186	2	29317790
Pubmed	LNX1 contributes to tumor growth by down-regulating p53 stability.	NUMB LNX1	1.69e-04	4	186	2	31533005
Pubmed	Whole-exome sequencing points to considerable genetic heterogeneity of cerebral palsy.	L1CAM TENM1	1.69e-04	4	186	2	25666757
Pubmed	Matrix metalloproteinase polymorphisms and survival in stage I non-small cell lung cancer.	MMP3 MMP12	1.69e-04	4	186	2	17000679
Pubmed	Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP).	CSRNP2 CSRNP3	1.69e-04	4	186	2	17726538
Pubmed	Extracellular matrix remodeling genes polymorphisms and risk of chronic bronchitis and recurrent pneumonia in children.	MMP3 MMP12	1.69e-04	4	186	2	23575435
Pubmed	Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy.	MMP3 MMP12	1.69e-04	4	186	2	11689884
Pubmed	Matrix metalloproteinase genes on chromosome 11q22 and the risk of anterior cruciate ligament (ACL) rupture.	MMP3 MMP12	1.69e-04	4	186	2	21410539
Pubmed	FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy.	CUL1 FBXO32	1.69e-04	4	186	2	26753747
Pubmed	Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease.	MMP3 MMP12	1.69e-04	4	186	2	12103254
Pubmed	Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva.	MMP3 MMP12	1.69e-04	4	186	2	27391467
Pubmed	Ligand-of-Numb protein X is an endocytic scaffold for junctional adhesion molecule 4.	NUMB LNX1	1.69e-04	4	186	2	16832352
Pubmed	4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL.	PNPLA2 EGR1	1.69e-04	4	186	2	25814662
Pubmed	Association of MMP1, MMP3, MMP9, and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population.	MMP3 MMP12	1.69e-04	4	186	2	19628284
Pubmed	The Lnx family proteins function as molecular scaffolds for Numb family proteins.	NUMB LNX1	1.69e-04	4	186	2	11922143
Pubmed	Functional polymorphisms in matrix metalloproteinases -1, -3, -9 and -12 in relation to cervical artery dissection.	MMP3 MMP12	1.69e-04	4	186	2	19664242
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	CKAP5 E2F7 DDX51 EEF1A2 DDX50 UBR5 ZC3HAV1	1.98e-04	221	186	7	29991511
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 EVC USP9Y SETBP1 TENM1 RP1 PHYHIPL BICC1 PSD4	5.08e-10	143	186	10	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 ABCA13 FAT3 PKHD1L1 ASXL3 TENM1 CNTNAP4 ADAMTS20 UNC13C ST18	5.87e-09	184	186	10	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 ABCA13 FAT3 PKHD1L1 ASXL3 TENM1 CNTNAP4 ADAMTS20 UNC13C ST18	5.87e-09	184	186	10	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 ABCA13 FAT3 PKHD1L1 ASXL3 TENM1 CNTNAP4 ADAMTS20 UNC13C ST18	5.87e-09	184	186	10	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 FAT3 SLCO3A1 EVC RGS12 WDFY3 PHYHIPL BICC1	5.82e-08	176	186	9	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ANK2 ABCA13 EXPH5 EVC KCNB2 RGS12 PHYHIPL BICC1	7.40e-08	181	186	9	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ANK2 ABCA13 EXPH5 EVC KCNB2 RGS12 PHYHIPL BICC1	7.76e-08	182	186	9	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ANK2 ABCA13 EXPH5 EVC RGS12 RP1 PHYHIPL BICC1	9.78e-08	187	186	9	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 EGR1 PHYHIPL BICC1	1.52e-07	197	186	9	b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCell	Tracheal-10x3prime_v2-Stromal-Schwann\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TTYH1 POT1 L1CAM SLC44A2 TSSC4 CDH19 SLC22A17 YEATS2 TANC1	1.66e-07	199	186	9	8dc65662c3ca1db2ba0091332f0658abc0afc5de
ToppCell	Tracheal-10x3prime_v2-Stromal-Schwann-Schwann_nonmyelinating\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TTYH1 POT1 L1CAM SLC44A2 TSSC4 CDH19 SLC22A17 YEATS2 TANC1	1.66e-07	199	186	9	a92718a3f1153b8d2196fd343ed5bc0ebc98cad7
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL11A1 ABCA13 FAT3 USP9Y PKHD1L1 MYPN TENM1 ST18	4.21e-07	162	186	8	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 FAT3 PKHD1L1 CSRNP3 UNC13C RP1 MMP3 SPINK5	5.80e-07	169	186	8	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 SLCO3A1 EVC KCNB2 RGS12 LRIG3 PHYHIPL	6.07e-07	170	186	8	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 EEF1A2 CNTNAP4 UNC13C ANKRD12 MMP3 NEUROD6 LYPD8	9.35e-07	180	186	8	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 FAT3 EVC RGS12 WDFY3 PHYHIPL BICC1	1.06e-06	183	186	8	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SKIDA1 KCNB2 EEF1A2 KCNH6 CSRNP3 PHYHIPL NPAS4	1.20e-06	186	186	8	2fab7abed16a894afdd0207e86fc43a25a77fb9e
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT3 SKIDA1 ADGRB2 NLGN3 NEUROD6 PHYHIPL ST18 NPAS4	1.20e-06	186	186	8	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SKIDA1 KCNB2 EEF1A2 KCNH6 CSRNP3 PHYHIPL NPAS4	1.20e-06	186	186	8	714765585a644bf9817ab6eb3001b43b3c2d2410
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 SKIDA1 KCNB2 EEF1A2 KCNH6 CSRNP3 PHYHIPL NPAS4	1.20e-06	186	186	8	ea2c8e0df038a00062d2098b4a9ac85141b9a728
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	USP53 PRUNE2 COL11A1 SLIT2 SETBP1 FBXO32 BICC1 NOTCH3	1.24e-06	187	186	8	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 FAT3 SLCO3A1 EVC WDFY3 PHYHIPL BICC1	1.35e-06	189	186	8	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTYH1 ATG9B MFSD4A EEF1A2 CCNG2 KLK8 FBXO32 SPINK5	1.46e-06	191	186	8	fbd8d337b4444fba8527a614e4a8bfb516ce0f66
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 FAT3 SLCO3A1 USP9Y CSRNP3 SETBP1 UNC13C TANC1	1.52e-06	192	186	8	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	ZNF438 FOXR1 VPS13D UBR5 ASXL3 ZBTB40 ADAMTS20	1.63e-06	135	186	7	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 FAT3 SLCO3A1 IGSF10 SLIT2 ASXL3 SETBP1 BICC1	1.64e-06	194	186	8	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT3 L1CAM GPRC6A KCNB2 ASXL3 FBXO32 PHYHIPL ST18	1.64e-06	194	186	8	2dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TMC7 ABCA13 FAT3 MUC19 EGR1 ASXL3 MYPN WDFY3	1.70e-06	195	186	8	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TMC7 ABCA13 FAT3 MUC19 EGR1 ASXL3 MYPN WDFY3	1.70e-06	195	186	8	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FOXR1 SEMA3C ATG9B ANK2 FAT3 STAP1 KCNH6 UNC13C	1.77e-06	196	186	8	72b6a68ee760599ea86cd2d712bfd17b7b4ee417
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRUNE2 SEMA3C TMC7 SLCO3A1 CDH19 CNTNAP4 FBXO32 ST18	1.84e-06	197	186	8	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)-\|Striatum / BrainAtlas - Mouse McCarroll V32	MALRD1 BARHL2 CCT8L1P SPOCD1 SPINK5	4.78e-06	59	186	5	3ab024fa7a927177da0dc764cee46dabdd008040
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)\|Striatum / BrainAtlas - Mouse McCarroll V32	MALRD1 BARHL2 CCT8L1P SPOCD1 SPINK5	4.78e-06	59	186	5	a72de8cda377c87fa9a6fbda72735d850650f9f4
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	JCAD CDC42BPA FAT3 MALRD1 MED12L BICC1 DNMT3B	6.17e-06	165	186	7	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	PRUNE2 ANK2 ADGRB2 CSRNP3 EGR1 BICC1 NOTCH3	6.68e-06	167	186	7	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	ABCA13 DGKH UNC13C TNS4 FBXO32 MMP3 SPINK5	7.80e-06	171	186	7	3965ced4be6db14265a90673502fceee425837ca
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TTYH1 L1CAM CDH19 KCNH6 NLGN3 TENM1 ADAMTS20	8.10e-06	172	186	7	8d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERCC6L ZNF395 HNMT SBNO2 KBTBD11 MED12L SPINK5	8.10e-06	172	186	7	1bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ATG9B COL11A1 MFSD4A CASTOR2 KCNB2 MYPN CNTNAP4	8.42e-06	173	186	7	7e3897868dd3f6e4974f593c60649a543ffc8693
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF1A2 SETBP1 TENM1 UNC13C ANKRD12 MMP3 LYPD8	9.07e-06	175	186	7	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 GC EGR1 MED12L NUMB AKAP13 MARCKS	9.07e-06	175	186	7	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	E2F7 TBC1D24 SOX7 ZBTB40 CNTNAP4 ADAMTS20 MDGA1	9.41e-06	176	186	7	27e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 EXPH5 FAT3 EVC RGS12 MED12L RP1	1.05e-05	179	186	7	55bc69f107fc710db7617c428575792adfdbbcc1
ToppCell	(0)_Normal/No_Treatment\|World / Stress and Cell class	HHEX INPP5D FRAT2 STAP1 ANKRD13A PISD DNMT3B	1.13e-05	181	186	7	4077282c45a37403f47e8d1b9ac102e6b1ba2cf9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 FAT3 SLCO3A1 KCNB2 PHYHIPL BICC1	1.13e-05	181	186	7	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 SLCO3A1 EVC WDFY3 PHYHIPL BICC1	1.17e-05	182	186	7	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 FAT3 EVC WDFY3 PHYHIPL BICC1	1.21e-05	183	186	7	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 EXPH5 FAT3 EVC RGS12 MED12L RP1	1.21e-05	183	186	7	83592c332b1e82673f993d37c7f480befdc3dcda
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXPH5 EEF1A2 CNTNAP4 UNC13C MDGA1 NEUROD6 LYPD8	1.30e-05	185	186	7	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	SMYD5 FRAT2 RGS12 CCNG2 VPS13D IER5L TACC3	1.35e-05	186	186	7	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 SLCO3A1 EVC WDFY3 PHYHIPL BICC1	1.35e-05	186	186	7	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 EVC TENM1 RP1 PHYHIPL BICC1	1.35e-05	186	186	7	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ANK2 DGKH NUMB WDFY3 PHYHIPL BICC1	1.40e-05	187	186	7	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 EVC TENM1 RP1 PHYHIPL BICC1	1.40e-05	187	186	7	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	JCAD SEMA3C EXPH5 CASTOR2 ARID5B TNS4 WDFY3	1.40e-05	187	186	7	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 GPRC6A KCNB2 STAP1 EEF1A2 KCNH6 ST18	1.44e-05	188	186	7	1f912ea015f50570e848259d948a0ba682d64bb4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCA13 EVC TENM1 RP1 PHYHIPL BICC1	1.44e-05	188	186	7	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	10x5'-GI_small-bowel-Lymphocytic_B-Memory_B_cells\|GI_small-bowel / Manually curated celltypes from each tissue	HHEX TLR9 STAP1 SETBP1 ARID5B LY9 MARCKS	1.44e-05	188	186	7	ab1384e6f71053946368502282aeebf1ba92d33e
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	CDC42BPA SLCO3A1 MFSD4A SETBP1 RP1 WDFY3 BICC1	1.49e-05	189	186	7	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 SEMA3C FAT3 CDH19 FBXO32 BICC1 NOTCH3	1.49e-05	189	186	7	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ANK2 EXPH5 EVC RGS12 RP1 BICC1	1.55e-05	190	186	7	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 ACACA ANK2 SLCO3A1 EGR1 SETBP1 UNC13C	1.55e-05	190	186	7	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 NGB L1CAM KCNB2 EEF1A2 NEUROD6 ST18	1.55e-05	190	186	7	bdbfaced785db79ff965f332759be258dbf743cf
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ANK2 EXPH5 EVC RGS12 RP1 BICC1	1.55e-05	190	186	7	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 L1CAM MFSD4A SLIT2 NINL TANC1 LNX1	1.60e-05	191	186	7	5a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 L1CAM MFSD4A SLIT2 NINL TANC1 LNX1	1.60e-05	191	186	7	78bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 FAT3 SLCO3A1 IGSF10 SLIT2 SETBP1 BICC1	1.60e-05	191	186	7	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 FAT3 SLCO3A1 EVC DGKH PHYHIPL BICC1	1.60e-05	191	186	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	L1CAM MFSD4A ZDBF2 KCNB2 EEF1A2 TENM1 ANKRD12	1.65e-05	192	186	7	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 FAT3 SLCO3A1 IGSF10 SLIT2 SETBP1 BICC1	1.65e-05	192	186	7	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	3'-Child09-12-SmallIntestine-Neuronal\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.65e-05	192	186	7	24f40dadec04f4f99c31000fa9f09d07148fa190
ToppCell	3'-Child09-12-SmallIntestine-Neuronal-Glial_mature\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.65e-05	192	186	7	ac507fd7cf3b3e521a15ef03bb4e81eb23807985
ToppCell	3'-Child09-12-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.65e-05	192	186	7	71e04e197825856c6d4278fc76c58ab17ffa2387
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 NGB L1CAM KCNB2 EEF1A2 IGSF10 NEUROD6	1.71e-05	193	186	7	a189d46c39067b717509cd144e0225cc93d7731d
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRUNE2 SLCO3A1 CASTOR2 CDH19 CNTNAP4 FBXO32 ST18	1.71e-05	193	186	7	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 FAT3 IGSF10 SLIT2 ASXL3 SETBP1 BICC1	1.71e-05	193	186	7	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.77e-05	194	186	7	d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.77e-05	194	186	7	408dfc7060095972a54ae37ae8105521df6fbbee
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-memory_B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HHEX INPP5D STAP1 ANKRD13A SETBP1 ARID5B MARCKS	1.77e-05	194	186	7	f0c113edb706d53792892115b67277a285219942
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.77e-05	194	186	7	bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell	3'-Child04-06-SmallIntestine-Neuronal\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.83e-05	195	186	7	8d286622f86c844d1b06a106ee4a3f813eba05bb
ToppCell	3'-Child04-06-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.83e-05	195	186	7	359b9d791e26844675c3c60cf69d8ab69c2cf400
ToppCell	3'-Child04-06-SmallIntestine-Neuronal-Glial_mature\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 SEMA3C ANK2 L1CAM CDH19 SLC22A17 MARCKS	1.83e-05	195	186	7	4193e58788e90c3d1049ef5cf9800a8c4d8ac354
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP53 SEMA3C ANK2 MYOC IGSF10 SLIT2 BICC1	1.83e-05	195	186	7	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B-Memory_B_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	HHEX PKHD1L1 STAP1 ANKRD13A SETBP1 LY9 MARCKS	1.89e-05	196	186	7	c450cd6b799932f5cce8326d1079114abeb71e95
ToppCell	Nasal_Brush-Epithelial-Goblet_1\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	PNPLA2 CDC42BPA SLC44A2 MFSD4A HNMT MUC5AC SPINK5	1.89e-05	196	186	7	e16f0831f1f677b28e4a8014f0aede7e713d4f04
ToppCell	Nasal_Brush-Epithelial-Goblet_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	PNPLA2 CDC42BPA SLC44A2 MFSD4A HNMT MUC5AC SPINK5	1.89e-05	196	186	7	71e88d9ca28168732bd91f2d4f8f53bb4187963a
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HHEX INPP5D STAP1 ANKRD13A SETBP1 LY9 MARCKS	1.95e-05	197	186	7	85b5d284e7799335a1829a5d2d56bb0845f5cec5
ToppCell	3'-Adult-LargeIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 ANK2 L1CAM CDH19 SLC22A17 NLGN3 PHYHIPL	2.02e-05	198	186	7	2488ea95003f218afb25ecc873805b825e6cc409
ToppCell	3'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 ANK2 L1CAM CDH19 SLC22A17 NLGN3 PHYHIPL	2.02e-05	198	186	7	991db02a76f7506848827601e927cf997cb520d3
ToppCell	3'-Adult-LargeIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTYH1 ANK2 L1CAM CDH19 SLC22A17 NLGN3 PHYHIPL	2.02e-05	198	186	7	98ab27335d126fa7817a46953948e524d91248f8
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	FAT3 MPDZ SLIT2 ASXL3 UNC13C MARCKS BICC1	2.08e-05	199	186	7	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH1 ANK2 TMC7 CDH19 SLC22A17 PHYHIPL ST18	2.08e-05	199	186	7	5d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH1 ANK2 TMC7 CDH19 SLC22A17 PHYHIPL ST18	2.08e-05	199	186	7	6fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HHEX PKHD1L1 STAP1 ANKRD13A SETBP1 LY9 MARCKS	2.08e-05	199	186	7	1aa963ed5205d6d52262b1597a5d08707a95c3ca
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH1 ANK2 TMC7 CDH19 SLC22A17 PHYHIPL ST18	2.08e-05	199	186	7	9dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTYH1 ANK2 TMC7 CDH19 SLC22A17 PHYHIPL ST18	2.08e-05	199	186	7	1bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	SEMA3C L1CAM SLIT2 CSRNP3 ASXL3 ANKRD12 NEUROD6	2.15e-05	200	186	7	306926cb7a847871641f02e03d52dc56fd55711c
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	RUSC1 SLCO3A1 SLIT2 CSRNP3 ASXL3 TENM1 ANKRD12	2.15e-05	200	186	7	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	SEMA3C ANK2 L1CAM RUSC1 DDX51 CSRNP3 NEUROD6	2.15e-05	200	186	7	5b3df61ff421846ef4cabf1bd5355534c8b95509
Disease	intraocular pressure measurement	JCAD HHEX PNPLA2 SEMA3C MYOC ADGRB2 CKAP5 TRIOBP MFRP ARID5B ADAMTS20 AKAP13 FBXO32 BICC1	2.85e-06	509	178	14	EFO_0004695
Disease	Neurodevelopmental Disorders	ANK2 EEF1A2 SETD2 ASXL3 SETBP1 WDFY3	2.19e-05	93	178	6	C1535926
Disease	matrix metalloproteinase measurement, Alzheimer disease, Alzheimer's disease biomarker measurement	MMP3 MMP12	3.62e-05	2	178	2	EFO_0004744, EFO_0006514, MONDO_0004975
Disease	Clumsiness - motor delay	MED12L MED13	3.62e-05	2	178	2	C0520947
Disease	level of stromelysin-1 in blood serum	MMP3 MMP12	3.62e-05	2	178	2	OBA_2042390
Disease	pulse pressure measurement	ZNF438 JCAD RIN3 COL11A1 ANK2 FAT3 CKAP5 TRIOBP MEI1 AHDC1 SLC22A17 LRIG3 MALRD1 MYPN AKAP13 FBXO32 LNX1 DHX34 ST18 BICC1 NOTCH3 DNMT3B	3.65e-05	1392	178	22	EFO_0005763
Disease	glaucoma	SEMA3C COL11A1 MYOC TRIOBP FBXO32 ST18 BICC1	4.35e-05	154	178	7	MONDO_0005041
Disease	neutrophil count	USP53 PRUNE2 JCAD RIN3 COL11A1 CDC42BPA INPP5D MUS81 E2F2 GC DGKH FRAT2 SBNO2 ANKRD13A ZC3H7A SETD2 UBXN4 AKAP13 UNC13C RP1 LNX1	9.66e-05	1382	178	21	EFO_0004833
Disease	blood urea nitrogen measurement	CDC42BPA TRMT1 DGKH SETBP1 ARID5B AKAP13 TANC1 ASCC3 DHX34 BICC1 PSD4	1.02e-04	452	178	11	EFO_0004741
Disease	Motor delay	MED12L MED13	1.08e-04	3	178	2	C1854301
Disease	anxiety disorder (biomarker_via_orthology)	L1CAM DNMT3B	1.08e-04	3	178	2	DOID:2030 (biomarker_via_orthology)
Disease	emphysema pattern measurement	JCAD RIN3 MMP12	1.95e-04	19	178	3	EFO_0005850
Disease	Gait, Rigid	L1CAM MSL3	2.15e-04	4	178	2	C0234996
Disease	Gait Disorders, Neurologic	L1CAM MSL3	2.15e-04	4	178	2	C0751830
Disease	Gait, Widebased	L1CAM MSL3	2.15e-04	4	178	2	C0751832
Disease	Gait, Frontal	L1CAM MSL3	2.15e-04	4	178	2	C0751831
Disease	Gait Disorder, Sensorimotor	L1CAM MSL3	2.15e-04	4	178	2	C0751829
Disease	Gait, Broadened	L1CAM MSL3	2.15e-04	4	178	2	C0235000
Disease	Gait, Festinating	L1CAM MSL3	2.15e-04	4	178	2	C0231694
Disease	Cerebellar ataxic gait	L1CAM MSL3	2.15e-04	4	178	2	C0231695
Disease	Charcot Gait	L1CAM MSL3	2.15e-04	4	178	2	C0231693
Disease	Gait, Scissors	L1CAM MSL3	2.15e-04	4	178	2	C0231698
Disease	Gait, Hemiplegic	L1CAM MSL3	2.15e-04	4	178	2	C0231696
Disease	Gait, Athetotic	L1CAM MSL3	2.15e-04	4	178	2	C0231689
Disease	Spastic gait	L1CAM MSL3	2.15e-04	4	178	2	C0231687
Disease	Gait, Shuffling	L1CAM MSL3	2.15e-04	4	178	2	C0231688
Disease	Waddling gait	L1CAM MSL3	2.15e-04	4	178	2	C0231712
Disease	Marche a Petit Pas	L1CAM MSL3	2.15e-04	4	178	2	C0427169
Disease	Gait, Hysterical	L1CAM MSL3	2.15e-04	4	178	2	C0427177
Disease	Rapid Fatigue of Gait	L1CAM MSL3	2.15e-04	4	178	2	C0427128
Disease	Gait, Stumbling	L1CAM MSL3	2.15e-04	4	178	2	C0337210
Disease	Gait, Drop Foot	L1CAM MSL3	2.15e-04	4	178	2	C0427149
Disease	body weight	HHEX COL11A1 SLC44A2 E2F7 DGKH KCNB2 CDH19 ZZEF1 SBNO2 SLIT2 NCOR1 SETD2 EGR1 ASXL3 SETBP1 CHFR CNTNAP4 SENP6 LNX1	2.35e-04	1261	178	19	EFO_0004338
Disease	bone density, lean body mass	RIN3 CSRNP3 ZBTB40	2.65e-04	21	178	3	EFO_0003923, EFO_0004995
Disease	Delayed speech and language development	MED12L MED13	3.58e-04	5	178	2	C0454644
Disease	Gait, Unsteady	L1CAM MSL3	3.58e-04	5	178	2	C0231686
Disease	Sjogren's syndrome (is_marker_for)	MUC19 MMP3 MUC5AC	3.98e-04	24	178	3	DOID:12894 (is_marker_for)
Disease	Chanarin-Dorfman syndrome (implicated_via_orthology)	PNPLA2 PNPLA5	5.34e-04	6	178	2	DOID:0050729 (implicated_via_orthology)
Disease	hydrocephalus (is_implicated_in)	L1CAM MPDZ	5.34e-04	6	178	2	DOID:10908 (is_implicated_in)
Disease	brain measurement, neuroimaging measurement	ZNF438 RIN3 COL11A1 FAT3 SKIDA1 TRIOBP SLIT2 ADAMTS20 TACC3 LNX1 DNMT3B	5.42e-04	550	178	11	EFO_0004346, EFO_0004464
Disease	malignant mesothelioma (is_implicated_in)	SETD2 BCL10	7.45e-04	7	178	2	DOID:1790 (is_implicated_in)
Disease	retinal detachment	FAT3 CDH19	7.45e-04	7	178	2	EFO_0005773
Disease	Malignant neoplasm of breast	ZNF438 HHEX COL11A1 TBC1D9B ANK2 RNF149 PKDREJ NCOR1 SETD2 LBX1 SETBP1 TENM1 MMP3 SPOCD1 NOTCH3 DNMT3B	8.35e-04	1074	178	16	C0006142
Disease	Abnormality of refraction	JCAD FAT3 POT1 EVC GC ZZEF1 BARHL2 ADAMTS20 AKAP13 ST18 BICC1 MOCOS	8.37e-04	673	178	12	HP_0000539
Disease	cardiovascular measurement, left ventricular function	KCNB2 SLIT2	9.89e-04	8	178	2	EFO_0004295, EFO_0004298
Disease	crescentic glomerulonephritis (biomarker_via_orthology)	MMP3 MMP12	9.89e-04	8	178	2	DOID:13139 (biomarker_via_orthology)
Disease	psychotic symptoms	E2F7 NINL FBXO32 ST18	1.06e-03	74	178	4	EFO_0005940
Disease	open-angle glaucoma	SEMA3C COL11A1 MYOC TRIOBP FBXO32 BICC1	1.10e-03	191	178	6	EFO_0004190
Disease	triacylglycerol 58:10 measurement	MPDZ TANC1 LNX1	1.13e-03	34	178	3	EFO_0010437
Disease	Astigmatism	USP53 ABCA13 MPDZ LNX1 BICC1	1.14e-03	129	178	5	HP_0000483
Disease	Graves Disease	GC ARID5B	1.27e-03	9	178	2	C0018213
Disease	macrophage inflammatory protein 1b measurement	ZNF438 ACACA LRIG3 SETD2 SCAP	1.44e-03	136	178	5	EFO_0008219
Disease	cystic kidney disease (implicated_via_orthology)	SLIT2 BICC1	1.58e-03	10	178	2	DOID:2975 (implicated_via_orthology)
Disease	Intellectual Disability	TRMT1 SETD2 SETBP1 MSL3 MED12L ZBTB40 PISD ASCC3 MED13	1.65e-03	447	178	9	C3714756
Disease	primary angle closure glaucoma	COL11A1 ST18	1.92e-03	11	178	2	EFO_1001506
Disease	response to ondansetron, QT interval	MPDZ LNX1	1.92e-03	11	178	2	EFO_0004682, EFO_0020997
Disease	guanosine diphosphate measurement	KCNB2 NINL	1.92e-03	11	178	2	EFO_0010494
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 UBR5	1.92e-03	11	178	2	DOID:3717 (is_implicated_in)
Disease	obesity (implicated_via_orthology)	PNPLA2 PNPLA5 MED12L ADAMTS20 MED13 NOTCH3	2.01e-03	215	178	6	DOID:9970 (implicated_via_orthology)
Disease	late-onset Alzheimers disease	ZNF438 INPP5D FAT3 CKAP5 CDH19 LRIG3 ADAMTS20	2.05e-03	292	178	7	EFO_1001870
Disease	colorectal cancer (is_marker_for)	ERCC6L POT1 L1CAM SETD2 BARHL2	2.69e-03	157	178	5	DOID:9256 (is_marker_for)
Disease	matrix metalloproteinase measurement	MMP3 MMP12	2.70e-03	13	178	2	EFO_0004744
Disease	inositol measurement	SETBP1 NOTCH3	3.14e-03	14	178	2	EFO_0010504
Disease	atrial fibrillation (is_implicated_in)	ANK2 MMP3	3.14e-03	14	178	2	DOID:0060224 (is_implicated_in)
Disease	epilepsy (implicated_via_orthology)	ANK2 L1CAM EEF1A2 KCNH6 UNC13C	3.16e-03	163	178	5	DOID:1826 (implicated_via_orthology)
Disease	lung adenocarcinoma (is_implicated_in)	SETD2 UBR5 DNMT3B	3.24e-03	49	178	3	DOID:3910 (is_implicated_in)
Disease	lymphocyte count	TTYH1 JCAD ACACA EXPH5 E2F2 GC ZNF395 FRAT2 SBNO2 NCOR1 SETD2 ZGLP1 ARID5B MED12L LY9 ZC3HAV1 DNMT3B PSD4	3.36e-03	1464	178	18	EFO_0004587
Disease	Liver carcinoma	ACACA SLIT2 SCAP EGR1 KBTBD11 CNTNAP4 MTBP TACC3 NOTCH3	3.81e-03	507	178	9	C2239176
Disease	serum selenium measurement	TTYH1 INPP5D ARID5B	4.05e-03	53	178	3	EFO_0005266
Disease	response to acetylsalicylate	SETD2 SCAP	4.11e-03	16	178	2	GO_1903492
Disease	response to haloperidol	ARID5B CNTNAP4	4.11e-03	16	178	2	GO_1905119
Disease	hair colour measurement	RIN3 CDC42BPA SNX16 SETBP1 TGDS MED12L NINL AKAP13 UNC13C LNX1	4.32e-03	615	178	10	EFO_0007822
Disease	Malignant mesothelioma	DDX51 SETD2 MTMR4 BCL10	4.36e-03	109	178	4	C0345967
Disease	smoking status measurement	ZNF438 CDC42BPA FAT3 ADGRB2 SLIT2 CSRNP3 BARHL2 SETBP1 ARID5B MED12L CNTNAP4 ASCC3 MDGA1 NEUROD6 DNMT3B	4.63e-03	1160	178	15	EFO_0006527
Disease	dermatomyositis (is_marker_for)	TLR9 SLIT2	4.64e-03	17	178	2	DOID:10223 (is_marker_for)
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	SETD2 MED13	4.64e-03	17	178	2	DOID:0060307 (is_implicated_in)
Disease	myeloid white cell count	PRUNE2 JCAD RIN3 COL11A1 CDC42BPA E2F2 GC DGKH FRAT2 SETD2 MED12L RP1 ZC3HAV1	4.65e-03	937	178	13	EFO_0007988
Disease	optic cup area measurement	CDC42BPA FAT3 TRIOBP	4.73e-03	56	178	3	EFO_0006940
Disease	smoking behavior	CDC42BPA ADGRB2 BARHL2 SETBP1 ARID5B CNTNAP4 ASCC3	4.81e-03	341	178	7	EFO_0004318
Disease	large artery stroke	JCAD SLC22A17 MMP3 MMP12	4.95e-03	113	178	4	EFO_0005524
Disease	idiopathic pulmonary fibrosis	TTYH1 AKAP13 MUC5AC	4.97e-03	57	178	3	EFO_0000768
Disease	matrix metalloproteinase 12 measurement	MMP3 MMP12	5.20e-03	18	178	2	EFO_0010590
Disease	diet measurement, HOMA-B	FAT3 RAB11FIP2	5.78e-03	19	178	2	EFO_0004469, EFO_0008111
Disease	Osteochondrodysplasias	COL11A1 PISD	5.78e-03	19	178	2	C0029422
Disease	squamous cell carcinoma (is_marker_for)	TLR9 EGR1	5.78e-03	19	178	2	DOID:1749 (is_marker_for)
Disease	pancreatic ductal carcinoma (is_marker_for)	L1CAM MUC5AC DNMT3B	6.01e-03	61	178	3	DOID:3587 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ATAVGLSDFCSNPDP	TTYH1	266	Q9H313
NFVQLCLSAEPSEAP	ADGRB2	156	O60241
SCPTSEDCENNPVDS	BST1	156	Q10588
VPVNDVTSSPAAFCS	CDX4	96	O14627
ACSDQSSDSPPILEA	DNMT3B	26	Q9UBC3
DSCDSLNPPTTASFT	CSRNP2	36	Q9H175
SDGSDALNCSQPSPL	AKAP13	1051	Q12802
SPSNRFCVTSLDPDT	CASTOR2	181	A6NHX0
APALFENCSPASSES	ARHGEF33	636	A8MVX0
ESLSSSPPSDQECTF	CCNG2	316	Q16589
HPLTCDDPRFQDSSS	CGB1	156	A6NKQ9
CDDPLVSALPQASFS	CNTNAP4	31	Q9C0A0
ADPSPENDVFSSDCK	ABCA13	601	Q86UQ4
SVSDVLLDNSFTPPC	ACACA	1216	Q13085
FAPTKPFTGQDCANS	AHDC1	981	Q5TGY3
TELPGNSCAQDPASF	ANKRD12	1471	Q6UB98
PCSFPSQSLSDAESI	ANKRD12	1491	Q6UB98
TSPKSSPTEGCNDAF	BICC1	611	Q9H694
PAPFKSEADTTCSNQ	ASXL3	1586	Q9C0F0
PLPSFVTQSCNTDCE	ADAMTS20	891	P59510
AASTPLNPLSFQCEF	INTS7	606	Q9NVH2
NSEPALCDPNLSFDA	MMP12	276	P39900
AFGPCTEKNSTAPAD	SLC34A3	291	Q8N130
SDAEALQSSCRPDPQ	KIAA1107	486	Q9UPP5
RAESPQADCPSESFS	ANK2	2831	Q01484
ETFENLPKDCPSQDS	ANK2	2881	Q01484
CATANNPTAITPDEY	ANKRD13A	321	Q8IZ07
EPINSPNLSDNTCHF	MDGA1	741	Q8NFP4
SSKTEFCNPAFEPES	MFRP	16	Q9BY79
EACFSLSIPFNPEDS	NXF3	371	Q9H4D5
PFSGESDICPQDSST	PNPLA2	186	Q96AD5
FPIPLDESSSHECNQ	MED12L	711	Q86YW9
QSSPECTQSTFEGFP	MAGEC1	496	O60732
DPFLSEANCLPANST	MFSD4A	161	Q8N468
NKSSLDFSANPEPAS	LRIG3	1016	Q6UXM1
SSESPESLACPFPEQ	NLRP10	131	Q86W26
LDSSQCSPSPASQED	HHEX	231	Q03014
QFCPENSETLSAPLD	IHO1	46	Q8IYA8
APKATAPTELNCDDF	SPINK5	86	Q9NQ38
AALSPKCSDPAASEA	JCAD	716	Q9P266
SSSDESENFPKPCSQ	FANCM	1466	Q8IYD8
CDFLTGPNTPSSAVS	KCNH6	66	Q9H252
TPANCDPALSFDAVS	MMP3	286	P08254
SEPGEASFLPCSSQS	ARNTL2	476	Q8WYA1
SSENDSGVPCNSLYP	CSRNP3	506	Q8WYN3
PDCDSSAPKAAQAQE	COL11A1	241	P12107
SCAVPSNDSSPIYSA	EGR1	191	P18146
ETCNFNATAPPDLRA	HNMT	246	P50135
CSDTVAQTFPCDSNP	MUC19	1446	Q7Z5P9
ANCDRLSESSASPQP	MSL3	356	Q8N5Y2
LFNNSRCDPACSSPA	NOTCH3	1436	Q9UM47
FSVASPNESSCPEQS	MYOC	51	Q99972
EPQEDCSSPAALDSN	LNX1	596	Q8TBB1
SVFALSNEDPLPFCS	EXPH5	1201	Q8NEV8
TFTCQASFDPSLQPS	L1CAM	536	P32004
EERSASASNPDCQLP	MOCOS	181	Q96EN8
CPNIRNSFEDPCSLS	MUC5AC	606	P98088
PCEPANQSSDYDSTE	DGKH	646	Q86XP1
YNSSPSQEESSPCNL	GPR75	486	O95800
ACQTPLDPSTDFLNQ	MTMR4	821	Q9NYA4
CSPTDVDILQPSFNF	MEI1	946	Q5TIA1
ATSQPCQTPDDFVAA	GPRC6A	16	Q5T6X5
ESFQCDNGVSLPPDS	MALRD1	36	Q5VYJ5
VGPTDLFPCNFSKND	NLGN3	536	Q9NZ94
SPCNNLSPEDHSFLE	NPAS4	741	Q8IUM7
AKFQPASAPAEDCIS	CKAP5	1101	Q14008
CFEEPQPSTSTSDLF	CHFR	171	Q96EP1
FCQPETVFSSQPSDD	CCPG1	146	Q9ULG6
ASFTIPANSDAFLPC	IGSF10	1656	Q6WRI0
QVDSSPNCFADKPSD	KCNB2	826	Q92953
EDQFLSPTLACSSPL	E2F2	386	Q14209
CSSPLISFSPSLDQD	E2F2	396	Q14209
LLDFSEPDCPSSSAN	E2F7	266	Q96AV8
HPLTCDDPRFQDSSS	CGB3	126	P0DN86
PENYNSPASLDTRTC	COLCA2	61	A8K830
FPAQASECPVAAATA	FAM193B	286	Q96PV7
AAFQSEDPADPCALL	DDX51	391	Q8N8A6
PFQQSCTFALPSELE	CUL1	546	Q13616
CGDSKSDPPQEAAQF	EEF1A2	326	Q05639
SCEPFPDGATNNLSR	BCL10	121	O95999
PAPSQCALSRDSNEC	FAM120C	1051	Q9NX05
LDDVNDCSPAFIPSS	FAT3	926	Q8TDW7
SQPPQKEEDASCSEA	FOXR1	86	Q6PIV2
SEDNPQTLLFSATCP	DDX50	316	Q9BQ39
LSNCTSPLPEAFLAN	ATG9B	756	Q674R7
ADFRSQATPSPCSEI	BARHL2	41	Q9NY43
ASSACAAPSQEAQPE	MARCKS	306	P29966
AFCSSQAEAPADTPE	LY9	486	Q9HBG7
FECANVNSLTPTSAP	LYPD8	196	Q6UX82
DLSSSDESCPAPQRQ	ANKS3	241	Q6ZW76
TSPRENFPDTLNCAE	KLK8	161	O60259
VNIAAAPCDTLDFSP	KNDC1	1211	Q76NI1
ETFPSSNESRQCPNA	SLC44A2	411	Q8IWA5
ECEPPSNSNITAFAL	EVC	101	P57679
SPLTDQPASSQDCSE	LBX1	256	P52954
NPESCSVSLSPQDFI	FBXO32	336	Q969P5
SPFTRSAQSSPECAA	DHX34	616	Q14147
PDLTCLIDTNFSAQP	SCAP	871	Q12770
DKLSSPAAFLPACNS	C2CD5	246	Q86YS7
SDCDQDLSQPPFSKS	CCDC159	276	P0C7I6
ANTDPCAPPFDSLQT	CDH19	706	Q9H159
DFCPDSSPDASNISN	IER5L	341	Q5T953
CRQFSSPEDCLSSPE	NGB	46	Q9NPG2
EPSASSPQYACDFNL	ERCC6L	941	Q2NKX8
LQLDAAQDSPASPCA	FRAT2	51	O75474
ASINPEDSTFPACSV	MTBP	56	Q96DY7
NPIFIEDCSSALPTD	RIN3	236	Q8TB24
KETCNPSDTFFPSDG	RP1	1271	P56715
CLTSFPPVADTFQSS	HOXA2	21	O43364
CSQITNAFSTPEDPF	NUMB	331	P49757
SCSTEFNTGKPPQDS	PHYHIPL	231	Q96FC7
SSSPDPGLDSNCNAL	RUSC1	171	Q9BVN2
DVLEPEQTFFSSPCQ	SOX7	211	Q9BT81
VSADAAPDCPETSNQ	TRMT1	631	Q9NXH9
NTENCDFLFSPPEVT	TACC3	16	Q9Y6A5
LASFPDTCQPASLNE	PRUNE2	2591	Q8WUY3
NTTFLECAPKSPQAS	SEMA3C	586	Q99985
HPLEPDSSASCFQQL	SLCO3A1	321	Q9UIG8
DLNLFASPPDSNFVC	RNF151	6	Q2KHN1
LENTCPLPATSSFSF	SLC22A17	281	Q8WUG5
GENLDLSCFADSNPP	PSG6	346	Q00889
LSNNLPFADCPSTIT	PNPLA5	171	Q7Z6Z6
PFASQSALFDPACTV	PKDREJ	1036	Q9NTG1
PEPQSDNDSSATCSA	NCOR1	871	O75376
ICQSEPDDSFPSSGS	POT1	306	Q9NUX5
FSNPLFLASPCSENS	PSD4	246	Q8NDX1
CPEFATDLPSSQTDP	SKIDA1	641	Q1XH10
SSCEAKEVPFSNENP	INPP5D	136	Q92835
CSFSYPVDSQTDSDP	SIGLEC7	46	Q9Y286
DNEPSCSPAAQELLT	TANC1	126	Q9C0D5
SDPPSCDISNFISPN	TENM1	971	Q9UKZ4
ASSLPPKTCDFAQDS	SBNO2	81	Q9Y2G9
PATACLSSPADLAQF	CCT8L1P	256	A6NM43
CTNLFSPFGAADQDP	MED13	1196	Q9UHV7
EDFGSPQKSCSPSFD	NINL	181	Q9Y2I6
TDALDQFERSPSCTP	CDC42BPA	961	Q5VT25
LCFSSGEESPPQSLA	KBTBD11	41	O94819
PFLPDTSDAEHQCQS	TRIOBP	1086	Q9H2D6
RDKIDDSQPPFCSSD	ST18	176	O60284
PLSSRQSFCAQEAPT	TBC1D9B	436	Q66K14
CFTESPESEPQEASF	ARID5B	581	Q14865
PFPSSSATAACNATN	ASCC3	121	Q8N3C0
ENCSFTPSSFSVELP	C12orf40	146	Q86WS4
KDSSGSFSPCQPFLE	C15orf39	201	Q6ZRI6
AFCQPELDSISTCPN	USP53	1016	Q70EK8
SSSCLPLPEFVDNTQ	TBC1D24	86	Q9ULP9
QPTNPYASSKAAAEC	TGDS	161	O95455
SASPAESEPQCDPSF	RNF149	361	Q8NC42
LDLPGSCATFDSQNP	USP51	516	Q70EK9
NAFPSTSCENSFPED	SETDB2	96	Q96T68
ATDSFDSRAEQIPPC	WDFY3	776	Q8IZQ1
FENPSLCASNSEPLK	RGS12	151	O14924
DPDTNGCLEFPASSL	RGS12	366	O14924
SYDLTQDDNSSPCPG	UNC13C	711	Q8NB66
TSSSIFQDDLGPPQC	MPDZ	1971	O75970
PSSEDFRPNCSTLNF	TLR9	461	Q9NR96
SQTLSDAPFTTCPEG	TNS4	416	Q8IZW8
SSAAQAPPQSAALCL	SPOCD1	316	Q6ZMY3
PPAASCDSFKNQLVT	PISD	231	Q9UG56
NESVPSRFSPECPNS	TRBV4-1	76	A0A577
PFICSTDENTGQEPS	STAP1	266	Q9ULZ2
LAAPTDCVSSFNQDP	TSSC4	191	Q9Y5U2
AAPQPFTTSDDTPCQ	ZNF395	41	Q9H8N7
SDFASNCCSINSPPL	GC	446	P02774
FDCDASPQSTSDYPQ	ZDBF2	496	Q9HCK1
QEPPDALALSCQSSF	SENP6	426	Q9GZR1
NDDNSCSPLSRCPTE	SLIT2	716	O94813
DSPCDLKSPNAFSEN	RAB11FIP2	381	Q7L804
SPGFNCSDVLTNDDP	PKHD1L1	3541	Q86WI1
PGPSSQACDNLSLSD	USP9Y	2141	O00507
NPSLCNSEAENIEPS	SETD2	801	Q9BYW2
ASTPCFPIENFLDSL	ZNF229	146	Q9UJW7
PPLTSSLEDFCSSLN	ZC3H7A	346	Q8IWR0
SCQTQISDSPADASP	ZZEF1	2036	O43149
DTSDGSCTELPFKQP	ZBTB49	196	Q6ZSB9
NQPASAAKCTGDFSP	TASOR2	1526	Q5VWN6
PPQFDSCVDTRSNPS	ZC3HAV1	861	Q7Z2W4
NPAYSVPSSQELEAC	TMEM129	271	A0AVI4
HSCVPNAETSFPENN	SMYD5	316	Q6GMV2
NKPCLSFSEPENAVS	SNX16	316	P57768
VSTPSASFEPNNTCE	UBXN4	131	Q92575
SFTNQFPSDAPLEEA	UBXN4	331	Q92575
FCSLDNPEAIPSDTS	SETBP1	896	Q9Y6X0
VSQQSACESAFCPPT	ZNF438	351	Q7Z4V0
SLPCSSRSQESPADA	ZGLP1	166	P0C6A0
FLACTVDSNPPASLS	SIGLEC14	271	Q08ET2
QIDSEPECPSSFSSA	YEATS2	1256	Q9ULM3
PECPSSFSSADNLCR	YEATS2	1261	Q9ULM3
CQNSSGPDADPSSLL	UBR5	691	O95071
EACSPSPAVQTFSEA	ZBTB40	211	Q9NUA8
HPENLSLDSSCFSSP	TMC7	21	Q7Z402
SLDSSCFSSPPVNFL	TMC7	26	Q7Z402
EDLNKYPASATSSPC	VPS13D	1556	Q5THJ4
VADSPNSRLCDFFDP	DUSP18	71	Q8NEJ0
SPNPLCSLLTFSDFN	MUS81	446	Q96NY9
NFCQDNPRSPTSSKE	MYPN	116	Q86TC9
ESFYESTSPECASPQ	NEUROD6	241	Q96NK8