Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCl_channel-K

CLCNKA CLCNKB

1.16e-052642IPR002250
DomainCl-channel_core

CLCNKA CLCNKB

4.10e-049642IPR014743
Domain-

CLCNKA CLCNKB

4.10e-0496421.10.3080.10
DomainVoltage_CLC

CLCNKA CLCNKB

4.10e-049642PF00654
DomainCl-channel_volt-gated

CLCNKA CLCNKB

4.10e-049642IPR001807
DomainZnF_GATA

GATA3 RERE

7.46e-0412642SM00401
DomainBTB

KLHL10 GZF1 ZBTB17 KLHL30

1.06e-03131644PF00651
DomainZnf_GATA

GATA3 RERE

1.18e-0315642IPR000679
DomainGATA

GATA3 RERE

1.18e-0315642PF00320
DomainCBS

CLCNKA CLCNKB

1.34e-0316642SM00116
DomainGATA_ZN_FINGER_1

GATA3 RERE

1.34e-0316642PS00344
DomainGATA_ZN_FINGER_2

GATA3 RERE

1.34e-0316642PS50114
DomainCBS_dom

CLCNKA CLCNKB

2.11e-0320642IPR000644
DomainCBS

CLCNKA CLCNKB

2.11e-0320642PF00571
DomainCBS

CLCNKA CLCNKB

2.11e-0320642PS51371
DomainBTB

KLHL10 GZF1 ZBTB17 KLHL30

2.21e-03160644PS50097
DomainBTB

KLHL10 GZF1 ZBTB17 KLHL30

3.38e-03180644SM00225
DomainBTB/POZ_dom

KLHL10 GZF1 ZBTB17 KLHL30

3.73e-03185644IPR000210
DomainSKP1/BTB/POZ

KLHL10 GZF1 ZBTB17 KLHL30

4.02e-03189644IPR011333
DomainGDS_CDC24_CS

ARHGEF1 SOS2

7.89e-0339642IPR001331
Pubmed

Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.

CLCNKA CLCNKB

3.44e-0626528544406
Pubmed

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.

CLCNKA CLCNKB

3.44e-06265227335120
Pubmed

Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.

CLCNKA CLCNKB

3.44e-0626528812470
Pubmed

Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.

CLCNKA CLCNKB

3.44e-06265225919862
Pubmed

Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.

CLCNKA CLCNKB

3.44e-06265224863058
Pubmed

Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

CLCNKA CLCNKB

3.44e-0626529916798
Pubmed

Kidney kinetics and chloride ion pumps.

CLCNKA CLCNKB

3.44e-0626529916791
Pubmed

Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.

CLCNKA CLCNKB

3.44e-06265238069401
Pubmed

A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.

CLCNKA CLCNKB

3.44e-06265220805576
Pubmed

Human monocytes undergo functional re-programming during sepsis mediated by hypoxia-inducible factor-1α.

HIF1A IRAK3

3.44e-06265225746953
Pubmed

Salt wasting and deafness resulting from mutations in two chloride channels.

CLCNKA CLCNKB

3.44e-06265215044642
Pubmed

Two highly homologous members of the ClC chloride channel family in both rat and human kidney.

CLCNKA CLCNKB

3.44e-0626528041726
Pubmed

A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.

CLCNKA CLCNKB

3.44e-06265218648499
Pubmed

Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.

CLCNKA CLCNKB

3.44e-06265211014860
Pubmed

Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional.

CLCNKA CLCNKB

1.03e-05365226013830
Pubmed

Barttin increases surface expression and changes current properties of ClC-K channels.

CLCNKA CLCNKB

1.03e-05365212111250
Pubmed

Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension.

CLCNKA CLCNKB

1.03e-05365217510212
Pubmed

GATA3 interacts with and stabilizes HIF-1α to enhance cancer cell invasiveness.

HIF1A GATA3

1.03e-05365228263977
Pubmed

Histological expression of angiogenic factors: VEGF, PDGFRalpha, and HIF-1alpha in Hodgkin lymphoma.

HIF1A PDGFRA

1.03e-05365218950958
Pubmed

Activating Injury-Responsive Genes with Hypoxia Enhances Axon Regeneration through Neuronal HIF-1α.

HIF1A MAP3K12

1.03e-05365226526390
Pubmed

Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.

CLCNKA CLCNKB

1.03e-05365211734858
Pubmed

Barttin modulates trafficking and function of ClC-K channels.

CLCNKA CLCNKB

1.03e-05365216849430
Pubmed

Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction.

HIF1A PDGFRA

1.03e-05365234762860
Pubmed

Mechanisms of Disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance.

CLCNKA CLCNKB

1.03e-05365218094726
Pubmed

Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor.

CLCNKA CLCNKB

1.03e-05365210982849
Pubmed

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation.

ZBTB17 HUWE1

2.06e-05465216269333
Pubmed

Haplotype diversity in four genes (CLCNKA, CLCNKB, BSND, NEDD4L) involved in renal salt reabsorption.

CLCNKA CLCNKB

2.06e-05465217652939
Pubmed

Ubiquitination and inhibition of glycine receptor by HUWE1 in spinal cord dorsal horn.

GLRA1 HUWE1

2.06e-05465230721695
Pubmed

Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia.

GPR17 PDGFRA

2.06e-05465233108748
Pubmed

Notch signaling is necessary for GATA3 function in the initiation of T cell development.

PDGFRA GATA3

2.06e-05465218383037
Pubmed

Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis.

HIF1A PDGFRA

5.13e-05665232958928
Pubmed

Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency.

CLCNKA CLCNKB

7.18e-05765234499620
Pubmed

Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.

ZBTB17 HUWE1

7.18e-05765223699408
Pubmed

Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney.

CLCNKA CLCNKB

7.18e-05765211423561
Pubmed

Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells.

HIF1A PDGFRA

7.18e-05765236476935
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

BLM HIF1A ZNF143 GZF1 GATA3 DGKE TNKS RERE ZNF687 RETREG3

7.50e-051203651029180619
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HIF1A USF3 NAV1 ANKMY1 ST3GAL1 RERE HUWE1 MAP3K12 ADGRD1 PDZD2 SOS2

9.10e-051489651128611215
Pubmed

K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression.

HIF1A HUWE1

9.56e-05865227934968
Pubmed

Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death.

ZBTB17 HUWE1

9.56e-05865226212014
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNIP2 VPS8 NAV1 RERE ZDHHC17 PDZD2

1.14e-0440765612693553
Pubmed

Changing expression of chloride channels during preimplantation mouse development.

CLCNKA CLCNKB

1.23e-04965223115349
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

HIF1A ZNF143 ZBTB17 PLXNC1 GATA3 KDM5D ZDHHC17 ZNF687

1.29e-0480865820412781
Pubmed

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

HIF1A ZBTB17

1.53e-041065217418410
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

USF3 TNKS KDM5D RUNDC1 NUP153 SOS2

1.54e-0443065635044719
Pubmed

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).

HIF1A TNKS

1.87e-041165217003112
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NOB1 ARFGEF2 NAV1 PCNX1 ST3GAL1 WDFY3 HUWE1 TTC38 ZNF687

2.07e-04110565935748872
Pubmed

Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening.

KLHL10 ZBTB17 RERE

2.08e-046165335205757
Pubmed

Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.

SEPTIN3 PDZD2

2.24e-041265224528284
Pubmed

Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice.

HIF1A PDGFRA

2.24e-041265218521186
Pubmed

von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina.

HIF1A PDGFRA

2.65e-041365220388654
Pubmed

A human MAP kinase interactome.

USF3 ARHGEF1 NAV1 ZDHHC17 NUP153 SOS2

2.97e-0448665620936779
Pubmed

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.

SEPTIN3 HUWE1 SOS2

2.99e-046965332238831
Pubmed

GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.

PDGFRA GATA3

3.56e-041565224835466
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

FNIP2 TTC7A ARFGEF2 NAV1

4.16e-0418665433637726
Pubmed

Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

ZNF143 ZBTB17

4.59e-04176527557990
Pubmed

The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination.

GPR17 PDGFRA

5.16e-041865219838178
Pubmed

Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia.

GPR17 PDGFRA

5.16e-041865223575864
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

CKB BLM SERBP1 NUP153 ZNF687

5.53e-0435765537059091
Pubmed

Phosphoinositide 3-Kinase (PI3K) Subunit p110δ Is Essential for Trophoblast Cell Differentiation and Placental Development in Mouse.

HIF1A GATA3

5.76e-041965227306493
Pubmed

The ciliary protein Ftm is required for ventricular wall and septal development.

HIF1A PDGFRA

5.76e-041965223469020
Pubmed

Genome-wide association studies identify four ER negative-specific breast cancer risk loci.

N4BP2L1 NTN4

7.06e-042165223535733
Pubmed

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.

HUWE1 RETREG3

7.76e-042265237225996
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TTC7A DMXL2 PCNX1 WDFY3

8.48e-0422565412168954
Pubmed

Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.

VPS8 WDFY3

9.24e-042465217452356
Pubmed

Genome-wide association study of proneness to anger.

TCP11L1 ARFGEF2

9.24e-042465224489884
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PCNX1 WDFY3 ZDHHC17

9.37e-0410265310231032
Pubmed

A single-cell time-lapse of mouse prenatal development from gastrula to birth.

PDGFRA MUC16

1.00e-032565238355799
Pubmed

Twist1 controls a cell-specification switch governing cell fate decisions within the cardiac neural crest.

PDGFRA GATA3

1.00e-032565223555309
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

BLM N4BP2L1 ABCA5 GATA3 TNKS

1.16e-0342165519692168
Pubmed

Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression.

PDGFRA GATA3

1.17e-032765220081190
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ZNF143 NOB1 MUC16 IRAK3 WDFY3 ZNF687

1.23e-0363865631182584
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

SERBP1 ZBTB17 RERE HUWE1 NUP153

1.28e-0343165533660365
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

CKB SERBP1 NOB1 HUWE1

1.31e-0325365429911972
Pubmed

A census of human transcription factors: function, expression and evolution.

HIF1A USF3 ZNF143 ZBTB17 TFAP2E GATA3 RERE

1.51e-0390865719274049
Pubmed

Maternal diabetes alters transcriptional programs in the developing embryo.

HIF1A PDGFRA

1.65e-033265219538749
Pubmed

Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor.

PDGFRA GATA3

1.65e-033265227806288
GeneFamilyChloride voltage-gated channels

CLCNKA CLCNKB

2.57e-0410442302
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL10 GZF1 ZBTB17 KLHL30

3.11e-04134444861
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATA3 RERE

5.96e-041544282
GeneFamilyKelch like|BTB domain containing

KLHL10 KLHL30

4.68e-0342442617
CoexpressionGSE3982_MEMORY_CD4_TCELL_VS_TH2_UP

N4BP2L1 ABCA5 TNKS HUWE1 ZDHHC17 RETREG3 CRTAP

5.67e-07196657M5381
CoexpressionGSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP

NTN4 HIF1A ABCA5 PLXNC1 ST3GAL1 WDFY3

1.04e-05200656M7489
CoexpressionGSE7852_LN_VS_THYMUS_TREG_UP

CKB TTC7A PLXNC1 IRAK3 KDM5D ADGRD1

1.04e-05200656M5737
ToppCelldroplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB AUNIP SEPTIN3 PLXNC1 TCP11L1 GNA15 NUP153

6.35e-091736572eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

FNIP2 DMXL2 HIF1A PLXNC1 VPS8 IRAK3

4.22e-071966564929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

PLXNC1 IRAK3 GNA15 ADGRD1 PDZD2

4.99e-0617065597df5ffb328196c46568975d2d97722bcc753bf5
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNIP2 DMXL2 PLXNC1 IRAK3 ST3GAL1

6.24e-06178655fbf49766e1504df554856b84c0576c06f3167329
ToppCellnormal_Lymph_Node-Myeloid_cells-CD141+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

CKB FNIP2 SEPTIN3 NAV1 GNA15

6.42e-06179655ec995ccd6e1dbd06287ad836c232d9aed1cf94a8
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-DC1|lymph-node_spleen / Manually curated celltypes from each tissue

CKB FNIP2 SEPTIN3 NAV1 GNA15

7.14e-06183655c9e3d91f4c3395a73295b92e25608e0effb5d241
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GATA3 IRAK3 GNA15 ST3GAL1 ADGRD1

7.53e-061856557d6954bb04368ec62b284ba6c3021a15fbdfdee6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CKB CLCNKA CLCNKB ABCA5 COX7B

9.01e-0619265546ea8f4f292db70420b378c6fa3e55e99413679c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB ABCA5 RERE HUWE1 KDM5D

9.72e-061956557796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKB CLCNKA CLCNKB ABCA5 GATA3

9.96e-06196655f40d10ea7714067585493fdc89744714aa427de8
ToppCellControl-Myeloid-Macrophage|Control / Disease state, Lineage and Cell class

FNIP2 DMXL2 HIF1A IRAK3 GNA15

9.96e-06196655e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NTN4 GPR17 PDGFRA NAV1 PDZD2

9.96e-06196655f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NTN4 GPR17 PDGFRA NAV1 PDZD2

9.96e-06196655671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKB CLCNKA CLCNKB ABCA5 GATA3

9.96e-06196655b8350340d86e4524e9616a427e7f2e116a6fb3be
ToppCellBL-critical-LOC-Myeloid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DMXL2 HIF1A PLXNC1 IRAK3 WDFY3

1.02e-05197655932a7fae4979b561688e6222505df0f4e510ab11
ToppCellsevere-HLA-DR+_CD83+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC7A DMXL2 HIF1A IRAK3 WDFY3

1.05e-05198655a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GZF1 CLCNKB NOB1 COX7B MUC16

1.05e-05198655dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 IRAK3 GNA15 WDFY3 CRTAP

1.05e-05198655c26c909e95225440abdf558b1b858ffc06177000
ToppCellcritical|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FNIP2 DMXL2 HIF1A PLXNC1 IRAK3

1.07e-0519965516c55cb8a0e740342009965f0eddfb0ed2858fab
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HIF1A PLXNC1 IRAK3 WDFY3 SOS2

1.07e-05199655b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCellCOVID-19|World / group, cell type (main and fine annotations)

DMXL2 HIF1A PLXNC1 IRAK3 PCNX1

1.10e-05200655ac38a468559c33ee00152735ce6e408f3f48df84
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLXNC1 IRAK3 PCNX1 WDFY3 SOS2

1.10e-052006556beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NTN4 GPR17 PDGFRA NAV1 PDZD2

1.10e-05200655ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLXNC1 IRAK3 PCNX1 WDFY3 SOS2

1.10e-05200655026495aa7f1e7528a01d9199475cfc393677fc60
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HIF1A PLXNC1 IRAK3 WDFY3 SOS2

1.10e-05200655808571d74bb5c4d765ff13fc9393f88020d4e90d
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Grm5_(CA1_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CLCNKA MEIOC ZPBP2

3.65e-0544653598044d7c325bc48ac8ab0c0722b4bb263028d71
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PLXNC1 VPS8 NAV1 MUC16

6.68e-05149654a85a051e0d82430160967e72fa04b55f43e84513
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLXNC1 VPS8 NAV1 MUC16

6.86e-051506547a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL30 GLRA1 ADGRD1 ZNF687

7.04e-05151654ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCelldroplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB SEPTIN3 GNA15 ATP2B2

9.69e-05164654a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCellCOPD-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

TTC7A GATA3 IRAK3 GNA15

1.02e-04166654e2cad1db536d5ad5a34c337c19b5e7d1a2851552
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB NTN4 TRIM54 MUC16

1.04e-04167654720dc5855c856b478b5ca90156b30bfcc5518d60
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

IRAK3 GNA15 ADGRD1 PDZD2

1.06e-04168654d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB SEPTIN3 PLXNC1 TCP11L1

1.09e-0416965446f0f0de9a0894c454f93032e7a7a800f47c8276
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TFAP2E GLRA1 KDM5D ZNF687

1.11e-0417065445de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCell10x5'-Liver-Myeloid_Mac-Intermediate_macrophages|Liver / Manually curated celltypes from each tissue

DMXL2 HIF1A IRAK3 GNA15

1.14e-0417165425e0333743affdb662223fb5220b8a61fa02ad9f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 GPR17 NAV1 IRAK3

1.19e-04173654f193c63cc536d891c9d23043765e320252bb6e65
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BLM DMXL2 TCP11L1 ARFGEF2

1.19e-04173654efb8072475000888efe088d00e870c56ffad4172
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BLM DMXL2 TCP11L1 ARFGEF2

1.22e-0417465458300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLCNKA CLCNKB GATA3 COX7B

1.24e-04175654787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USF3 PCNX1 TTC38 RETREG3

1.30e-04177654d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 HIF1A GZF1 PLXNC1

1.30e-04177654f28243b51be104cb3adcde63f03fc2206ed3121e
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USF3 PCNX1 TTC38 RETREG3

1.30e-04177654f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLCNKA CLCNKB ABCA5 COX7B

1.30e-04177654dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

USF3 PCNX1 TTC38 RETREG3

1.30e-041776546978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

USF3 PCNX1 TTC38 RETREG3

1.30e-04177654936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

USF3 PCNX1 TTC38 RETREG3

1.30e-04177654d5aeda113afaa2425874394610344570c9078478
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NTN4 SEPTIN3 ADGRD1 PDZD2

1.36e-04179654adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB COX7B

1.39e-04180654fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCelldroplet-Kidney-nan-18m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB COX7B

1.39e-04180654cd743f81838ba210e5bb63fe0870918d7d2b0112
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB COX7B

1.39e-041806546763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BLM GPR17 PDGFRA PDZD2

1.45e-04182654a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BLM GPR17 PDGFRA PDZD2

1.45e-04182654831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellLPS_only-Myeloid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DMXL2 PLXNC1 IRAK3 GNA15

1.45e-04182654666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 HIF1A PDGFRA PLXNC1

1.48e-041836548e9d45c96b44558158e3d59613f64a73d5390c19
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB COX7B

1.48e-041836546b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 HIF1A PDGFRA PLXNC1

1.48e-041836540408d991ddb639594b45d5cb2432dd29289167b1
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 HIF1A PDGFRA PLXNC1

1.48e-0418365479f05b8a967124d831b0baef137e30659f5917a7
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB COX7B

1.48e-0418365403c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLCNKA CLCNKB ABCA5 GATA3

1.48e-041836542e831a4d99c6f983793df71c0994124c943c6da9
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FNIP2 HIF1A PDGFRA PLXNC1

1.51e-0418465492202e1cd0bba1ce4b061ebcb8a2af5bb590542a
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FNIP2 HIF1A PDGFRA PLXNC1

1.51e-041846547331535d469453a5264dcb0270a97f63d3b55201
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FNIP2 HIF1A PDGFRA PLXNC1

1.51e-04184654337e38a6b2b6770cc992d88b006829f194841b10
ToppCellLPS-IL1RA-Myeloid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DMXL2 PLXNC1 IRAK3 GNA15

1.54e-041856549b5fd87ea9d05e051ff1251578ecfbe5e8652853
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB FNIP2 DMXL2 OTOP2

1.57e-041866544046b701aa29712d9f7c774f8955215122c3c003
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GALNTL5 NAV1 MUC16 IRAK3

1.57e-0418665423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB FNIP2 DMXL2 OTOP2

1.57e-04186654bd5837033c1ffcbe5dd30195cc4846a2ba351bcd
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

GNA15 ZDHHC17 ADGRD1 ZNF687

1.57e-041866546259f0f2d5bc863782d09a901d6be2f387d1f074
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

N4BP2L1 PDGFRA GLRA1 ST3GAL1

1.57e-041866548ea708070166c858cd9bd871670655b0114c32a5
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

GATA3 DGKE RUNDC1 RETREG3

1.60e-04187654a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKB MEIOC CLCNKB ABCA5

1.60e-041876547b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NTN4 PDGFRA IRAK3 ADGRD1

1.64e-04188654aa516273cdde53c8c0295f06830972388f890c97
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLCNKA CLCNKB ABCA5 GATA3

1.64e-04188654bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell(7)_DC_1|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FNIP2 SEPTIN3 NAV1 GNA15

1.64e-04188654832887afa4a54ed80906bc02176d646529c13398
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLCNKA CLCNKB ABCA5 GATA3

1.64e-04188654eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CLCNKA CLCNKB ABCA5 GATA3

1.64e-041886541d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

FNIP2 CAPN13 AUNIP SEPTIN3

1.64e-04188654723348a1836a074e068320cb736ce6a953e0038f
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

CLCNKA CLCNKB MUC16 PDZD2

1.64e-04188654a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCelldroplet-Kidney-nan-3m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB COX7B

1.64e-041886546b185d0aaeea64f9ae584a9bcb9741658bb1c7bd
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB GATA3

1.67e-04189654e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA NAV1 IRAK3 ADGRD1

1.67e-041896546e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB GATA3

1.67e-04189654ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCellASK452-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

GATA3 MUC16 ZDHHC17 RUNDC1

1.67e-04189654f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like|lymph-node_spleen / Manually curated celltypes from each tissue

GATA3 GNA15 ADGRD1 PDZD2

1.71e-041906540c7eb8f4f2926af01bf44d5c9f239be7b81c67fe
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB COX7B

1.71e-0419065468ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCellControl-Myeloid-Transitioning_MDM|Control / group, cell type (main and fine annotations)

DMXL2 HIF1A IRAK3 GNA15

1.71e-04190654d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR17 PDGFRA NAV1 PDZD2

1.71e-041906546c7e1086c0a274cd5527c3104106e372811c9905
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 HIF1A PLXNC1 IRAK3

1.71e-04190654212f0d9defcc3174e225cc3d90e7814e238794b6
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB COX7B

1.71e-04190654010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKB CLCNKA CLCNKB COX7B

1.74e-041916548b34e06c398056e857a10c7653c70c0b1f181692
ToppCellControl-Myeloid-transitional_Macro|Control / Disease group,lineage and cell class （2021.01.30）

FNIP2 HIF1A PDGFRA PLXNC1

1.74e-041916543ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 PLXNC1 IRAK3 WDFY3

1.74e-0419165478ede1f15484414a2a54a2f0f0cb6abe0c6b6513
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNIP2 DMXL2 HIF1A PLXNC1

1.74e-041916540b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

CKB FNIP2 HIF1A PDZD2

1.74e-04191654ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic-Neutrophil|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 PLXNC1 IRAK3 WDFY3

1.74e-04191654d049ab9abd5f8d497eb7e3ccb39b28283298bc65
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

IRAK3 GNA15 ADGRD1 PDZD2

1.78e-04192654e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 HIF1A GNA15 CRTAP

1.78e-04192654f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKB CLCNKA CLCNKB COX7B

1.78e-041926547af2b5240b1fad2177d8022e5f4fc1fe9e8f03b5
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CKB CLCNKB ABCA5 COX7B

1.78e-041926544842a55650fc4687c9184d498a8c05c259d15186
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKB CLCNKA CLCNKB GATA3

1.78e-041926546fb56d062c35617b18b927704bf5fba894faed81
DrugICI 182,780; Up 200; 1uM; PC3; HT_HG-U133A

PDGFRA TCP11L1 GLRA1 GATA3 DGKE GNA15

1.82e-051926564429_UP
DrugAcyclovir [59277-89-3]; Up 200; 17.8uM; PC3; HT_HG-U133A

GPR17 PDGFRA PCNX1 GNA15 RERE SOS2

2.04e-051966564683_UP
DrugReserpine [50-55-5]; Down 200; 6.6uM; HL60; HT_HG-U133A

N4BP2L1 PLXNC1 ARFGEF2 TNKS WDFY3 SOS2

2.16e-051986563003_DN
DrugAG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A

GPR17 ARHGEF1 RERE HUWE1 TTC38 SOS2

2.22e-051996565949_DN
DrugOrlistat; Down 200; 10uM; MCF7; HT_HG-U133A

ARHGEF1 ANKMY1 WDFY3 RERE HUWE1 TTC38

2.29e-052006566415_DN
DiseaseBartter disease type 4B

CLCNKA CLCNKB

4.63e-062642cv:C4310805
DiseaseBARTTER SYNDROME, TYPE 4B

CLCNKA CLCNKB

4.63e-062642C2751312
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

4.63e-062642C4310805
DiseaseBartter disease type 3 (implicated_via_orthology)

CLCNKA CLCNKB

4.63e-062642DOID:0110144 (implicated_via_orthology)
DiseaseBartter disease type 4b (is_implicated_in)

CLCNKA CLCNKB

4.63e-062642DOID:0110146 (is_implicated_in)
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

4.63e-062642613090
DiseaseBartter disease (implicated_via_orthology)

CLCNKA CLCNKB

4.63e-062642DOID:445 (implicated_via_orthology)
DiseaseBartter syndrome

CLCNKA CLCNKB

6.91e-056642cv:C0004775
Diseasenephrogenic diabetes insipidus (implicated_via_orthology)

CLCNKA CLCNKB

2.06e-0410642DOID:12387 (implicated_via_orthology)
Diseaserespiratory system disease

PLXNC1 GATA3 GNA15 RERE

2.83e-04145644EFO_0000684
DiseasePrecursor B-cell lymphoblastic leukemia

PDGFRA GATA3

9.47e-0421642C1292769
Diseaseasthma

DMXL2 PLXNC1 GATA3 MUC16 GNA15 ZPBP2 RERE

1.19e-03751647MONDO_0004979
DiseaseInhalant adrenergic use measurement

GATA3 MUC16 RERE

1.20e-0396643EFO_0009941
Diseaseunipolar depression, response to selective serotonin reuptake inhibitor

SEPTIN3 PDZD2

1.24e-0324642EFO_0003761, EFO_0005658
Diseaseunipolar depression, depressive symptom measurement

FNIP2 ARFGEF2

1.46e-0326642EFO_0003761, EFO_0007006
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

CKB DMXL2 SEPTIN3 ARFGEF2 NAV1

1.73e-03398645EFO_0003756, EFO_0003888, EFO_0004337

Protein segments in the cluster

PeptideGeneStartEntry
APHSAALNVMHSEKD

ABCA5

951

Q8WWZ7
HLRQSSDPMLSEFKN

ARHGEF1

626

Q92888
ARTSNAKPFHSDLMN

ADGRD1

831

Q6QNK2
KSSPFNLLHEMHELR

GZF1

11

Q9H116
RDHKSGTPANVFLMH

GPR17

86

Q13304
FTSATHLDHVRPMFK

ARFGEF2

881

Q9Y6D5
KMPDSDRHLSSHFNL

CAPN13

476

Q6MZZ7
FISHRMDDVPSHSKA

DMXL2

1926

Q8TDJ6
MARQSHQKRTPDFHD

COX7B

21

P24311
EKPESRTSIHNFMAH

ATP2B2

1156

Q01814
QHADPGELHSRKSML

TFAP2E

331

Q6VUC0
DDLDFHLPSHAQDML

KLHL30

6

Q0D2K2
EDSVMDHHFRKPAND

SERBP1

336

Q8NC51
HLDFLKSDHPAVARM

PDGFRA

966

P16234
DMHHPGSRKFNTTER

MUC16

12871

Q8WXI7
DHRNRAMEKSHTPFS

FAM166C

51

A6NJV1
SDDGTLHMHFSRNPK

NOB1

301

Q9ULX3
PDLSAHNNHMAKVLT

CKB

21

P12277
PLDSKTFLSRHSLDM

HIF1A

236

Q16665
KADRENMFLTPSTDH

KDM5D

1486

Q9BY66
RMSIKLHQDHFTSPD

PCNX1

1856

Q96RV3
SHVLNDTHMKFSLPS

PLXNC1

711

O60486
MENSPLSKVARHFHS

PDZD2

1706

O15018
QPKLTDFAMAHFRSH

IRAK3

306

Q9Y616
RPESKHHASLVMSQD

GNA15

106

P30679
SSSHENRPLDLLHKM

HUWE1

3261

Q7Z6Z7
MHKFTAPLLAATSEH

PPP4R3C

471

Q6ZMV5
AMDHHKNPTRTLDVA

OTOP2

356

Q7RTS6
FNPAALSRHMSSLSH

GATA3

391

P23771
AAASTRFHQPHMERK

KLHL10

6

Q6JEL2
HERFQSLSFPHTKEM

BLM

641

P54132
AAAHTFLLKHPDDEM

CRTAP

166

O75718
HFPLFESHMNRLKSA

FNIP2

336

Q9P278
DMPNALSALSDLHAH

HBA1;

76

P69905
MLGTDFNHTNPELHK

GALNTL5

81

Q7Z4T8
NSDHLPMTSSFRKEL

ANKMY1

176

Q9P2S6
GLHHDLLLRKMSSSS

MAP3K12

596

Q12852
LMALNFHAHREKAPS

DGKE

381

P52429
LKLPEHMDSSHSHSL

CDKL5

571

O76039
GHHRMKTPFSTELSL

AUNIP

141

Q9H7T9
PNHGLHLSFRMLTFS

NAV1

1666

Q8NEY1
HMVLTEHDPFKRSAD

RUNDC1

521

Q96C34
DMHLPSFHLKDVLTT

TCP11L1

381

Q9NUJ3
PMNTSRFADHHDLLT

MEIOC

166

A2RUB1
LSPEFHEHFNKLMAR

SOS2

301

Q07890
HLAHLPSAMADSSFR

NTN4

86

Q9HB63
HHKSPMLNLFQEDEA

GLRA1

351

P23415
DSHDFVLRMNKAPTA

ST3GAL1

161

Q11201
KLPDSFSLHGSVMRH

VPS8

121

Q8N3P4
ANPMEHFARHSALTI

RERE

1341

Q9P2R6
RLSMKQHLDSLFDNH

CLCNKA

351

P51800
RLSMKQHLDSLFDNH

CLCNKB

351

P51801
RALHPERAMDNHSDS

RETREG3

246

Q86VR2
ESSRPLHSKAEQHLM

TRIM54

111

Q9BYV2
TLAMHKRTAHNDTEP

ZNF143

431

P52747
LTMHTAFDRKDNAHP

WDFY3

3396

Q8IZQ1
TGHSLRPLDLEFMKH

SEPTIN3

181

Q9UH03
KDFMTPLHVAAERAH

TNKS

556

O95271
HQSFMQSLLAPHLSD

USF3

1816

Q68DE3
LHRSHLNFSMLESPA

NUP153

131

P49790
SKSFFDHSMHSALPL

ZDHHC17

346

Q8IUH5
QDHPTDMLALKFSHD

TTC38

136

Q5R3I4
SFSDPTSKMRHLETH

ZBTB17

426

Q13105
KQSGMHLTLPDAHDA

TTC7A

656

Q9ULT0
SPLNLKTHFRTHGMA

ZNF687

1211

Q8N1G0
FNKTLPAMHFVDHSL

ZPBP2

256

Q6X784
TFHSVLHAEKPSRMN

N4BP2L1

181

Q5TBK1