Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	PAS	NCOA2 PASK AHRR NPAS1	8.08e-05	25	175	4	PF00989
Domain	PAS_fold	NCOA2 PASK AHRR NPAS1	8.08e-05	25	175	4	IPR013767
Domain	Unchr_dom_Cys-rich	KCP MUC5B SSPOP	2.16e-04	13	175	3	IPR014853
Domain	C8	KCP MUC5B SSPOP	2.16e-04	13	175	3	SM00832
Domain	PAS	NCOA2 PASK AHRR NPAS1	2.18e-04	32	175	4	SM00091
Domain	WTX	AMER1 AMER3	2.60e-04	3	175	2	PF09422
Domain	DUF3454	NOTCH1 NOTCH3	2.60e-04	3	175	2	PF11936
Domain	DUF3454_notch	NOTCH1 NOTCH3	2.60e-04	3	175	2	IPR024600
Domain	Uncharacterised_FAM123	AMER1 AMER3	2.60e-04	3	175	2	IPR019003
Domain	DUF3454	NOTCH1 NOTCH3	2.60e-04	3	175	2	SM01334
Domain	TIL_dom	KCP MUC5B SSPOP	2.73e-04	14	175	3	IPR002919
Domain	NPIP	NPIPB3 NPIPB5 NPIPB13	2.73e-04	14	175	3	IPR009443
Domain	PAS	NCOA2 PASK AHRR NPAS1	2.77e-04	34	175	4	PS50112
Domain	PAS	NCOA2 PASK AHRR NPAS1	2.77e-04	34	175	4	IPR000014
Domain	VWFC_1	COL5A2 KCP MUC5B SSPOP	3.47e-04	36	175	4	PS01208
Domain	VWF_type-D	KCP MUC5B SSPOP	4.14e-04	16	175	3	IPR001846
Domain	VWFD	KCP MUC5B SSPOP	4.14e-04	16	175	3	PS51233
Domain	VWD	KCP MUC5B SSPOP	4.14e-04	16	175	3	SM00216
Domain	VWD	KCP MUC5B SSPOP	4.14e-04	16	175	3	PF00094
Domain	VWFC_2	COL5A2 KCP MUC5B SSPOP	4.29e-04	38	175	4	PS50184
Domain	VWC	COL5A2 KCP MUC5B SSPOP	4.29e-04	38	175	4	SM00214
Domain	Notch	NOTCH1 NOTCH3	5.17e-04	4	175	2	IPR008297
Domain	NODP	NOTCH1 NOTCH3	5.17e-04	4	175	2	PF07684
Domain	Notch_NODP_dom	NOTCH1 NOTCH3	5.17e-04	4	175	2	IPR011656
Domain	Notch_NOD_dom	NOTCH1 NOTCH3	5.17e-04	4	175	2	IPR010660
Domain	NOD	NOTCH1 NOTCH3	5.17e-04	4	175	2	PF06816
Domain	NOD	NOTCH1 NOTCH3	5.17e-04	4	175	2	SM01338
Domain	NODP	NOTCH1 NOTCH3	5.17e-04	4	175	2	SM01339
Domain	VWF_dom	COL5A2 KCP MUC5B SSPOP	6.31e-04	42	175	4	IPR001007
Domain	VWC_out	KCP MUC5B SSPOP	7.02e-04	19	175	3	SM00215
Domain	RII_binding_1	AKAP12 AKAP13	8.57e-04	5	175	2	PF10522
Domain	LNR	NOTCH1 NOTCH3	8.57e-04	5	175	2	PS50258
Domain	RII_binding_1	AKAP12 AKAP13	8.57e-04	5	175	2	IPR018459
Domain	PH	TBC1D2 ARHGEF18 ARHGEF11 PLEKHM1 AFAP1L2 PLCH2 AKAP13 ARHGEF26 PSD4	1.27e-03	278	175	9	SM00233
Domain	PH_DOMAIN	TBC1D2 ARHGEF18 ARHGEF11 PLEKHM1 AFAP1L2 PLCH2 AKAP13 ARHGEF26 PSD4	1.30e-03	279	175	9	PS50003
Domain	PH_domain	TBC1D2 ARHGEF18 ARHGEF11 PLEKHM1 AFAP1L2 PLCH2 AKAP13 ARHGEF26 PSD4	1.33e-03	280	175	9	IPR001849
Domain	DM_2	DMRT3 DMRT2	1.78e-03	7	175	2	PS50809
Domain	DM	DMRT3 DMRT2	1.78e-03	7	175	2	SM00301
Domain	-	DMRT3 DMRT2	1.78e-03	7	175	2	4.10.1040.10
Domain	Notch_dom	NOTCH1 NOTCH3	1.78e-03	7	175	2	IPR000800
Domain	DM_DNA-bd	DMRT3 DMRT2	1.78e-03	7	175	2	IPR001275
Domain	DM	DMRT3 DMRT2	1.78e-03	7	175	2	PF00751
Domain	DM_1	DMRT3 DMRT2	1.78e-03	7	175	2	PS40000
Domain	Notch	NOTCH1 NOTCH3	1.78e-03	7	175	2	PF00066
Domain	NL	NOTCH1 NOTCH3	1.78e-03	7	175	2	SM00004
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RIN3 GBF1 ZNF628 NLRX1 CUL9 CARD10 ICE1 PPARA ARHGEF11 FAAP100 BIRC6 ELAC2 PLEKHM1 PCNX2 PIKFYVE MROH6 ZNF341 SETD5 ZNF408 SURF6 MCM3AP SCN5A KBTBD11 ANKRD11 AKAP13 POLL LRBA NOTCH1	6.14e-12	1105	183	28	35748872
Pubmed	Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.	PDGFRB NOTCH1 NOTCH3	1.43e-07	3	183	3	18483410
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	EFL1 ZNF318 FAAP100 BIRC6 CIZ1 ANKRD11 AKAP13 MEX3B NOTCH3	2.92e-07	168	183	9	30631154
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	TBC1D2 RNF213 ICE1 AMER3 ZNF831 BIRC6 SSPOP AFAP1L2 MROH8 TBC1D4 ZNF408 MCM3AP RECQL4 AKAP13 CHD6 PLXNB3 CXCR2	4.13e-07	736	183	17	29676528
Pubmed	Deficiency of Notch signaling in pericytes results in arteriovenous malformations.	PDGFRB NOTCH1 NOTCH3	1.42e-06	5	183	3	33148887
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	TBC1D2 ARHGEF18 ZNF217 ZNF318 STIL MCM3AP DCLRE1A NOTCH1	6.40e-06	184	183	8	32908313
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXM1 ZBTB38 BHLHA9 GON4L PPARA ATF6B CRX SOX7 HOXB2 USF3 DMRT3 DMRT2 FOXI2 DLX4 LBX2 ZNF541 NPAS1	6.94e-06	908	183	17	19274049
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	NCOA2 PDGFRB NPIPB12 TMEM54 DBNDD2 PKD1L1 GON4L FAM91A1 TACC2 KANK2 FAAP100 AFAP1L2 SURF6 RECQL4 TENM1 KDM4A ADAM17 GNAS MARCKS NOTCH1	7.08e-06	1215	183	20	15146197
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	AMER1 ZCCHC8 MAP3K8 OTUD1 FAM91A1 SNX16 TTC1 SOWAHC KANK2 PASK RIC8B MROH6 MCM3AP RNF10 SMN1 GNAS CDC27 CRTC2	1.04e-05	1038	183	18	26673895
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NCOA2 CACNA1C AMER1 ARHGEF18 RNF213 PPARA SSPOP PLEKHM1 LRP8 PCNX2 RIC8B USF3 TBC1D4 SETD5 ANKRD11 PPP1R9B AKAP13 CHD6 GNAS LRBA ARHGEF26 NOTCH3	1.31e-05	1489	183	22	28611215
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FOXM1 CAAP1 GBF1 ZCCHC8 TBC1D2 FAM91A1 ZNF217 ZNF318 DBN1 USP19 PASK RBM25 TBC1D4 MDC1 KLHDC4	1.65e-05	774	183	15	15302935
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ADAMTSL1 ARHGEF18 SSPOP TBC1D4 MCM3AP CCDC144A	2.04e-05	105	183	6	9628581
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	AMER1 GBF1 ZCCHC8 DBN1 TTC1 BIRC6 TBC1D4 PPP1R9B MAP3K21 NOTCH1 CRTC2	2.70e-05	446	183	11	24255178
Pubmed	Solution structures and backbone dynamics of arsenate reductase from Bacillus subtilis: reversible conformational switch associated with arsenate reduction.	ABCA1 ARHGEF11	2.75e-05	2	183	2	16192272
Pubmed	A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.	NOTCH1 NOTCH3	2.75e-05	2	183	2	21191019
Pubmed	S6 kinase 2 deficiency enhances ketone body production and increases peroxisome proliferator-activated receptor alpha activity in the liver.	RPS6KB2 PPARA	2.75e-05	2	183	2	22183976
Pubmed	Fusion of the AHRR and NCOA2 genes through a recurrent translocation t(5;8)(p15;q13) in soft tissue angiofibroma results in upregulation of aryl hydrocarbon receptor target genes.	NCOA2 AHRR	2.75e-05	2	183	2	22337624
Pubmed	Dysregulation of the ADAM17/Notch signalling pathways in endometriosis: from oxidative stress to fibrosis.	ADAM17 NOTCH1	2.75e-05	2	183	2	28486700
Pubmed	ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer.	ADAM17 NOTCH1	2.75e-05	2	183	2	20551051
Pubmed	Synergistic effect between polymorphisms of PPARA and ABCA1 genes on the premature coronary artery disease.	ABCA1 PPARA	2.75e-05	2	183	2	17608096
Pubmed	Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain.	ADAM17 NOTCH1	2.75e-05	2	183	2	9620803
Pubmed	Inhibition of cholesterol absorption associated with a PPAR alpha-dependent increase in ABC binding cassette transporter A1 in mice.	ABCA1 PPARA	2.75e-05	2	183	2	12897186
Pubmed	Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.	NOTCH1 NOTCH3	2.75e-05	2	183	2	21768299
Pubmed	Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.	NOTCH1 NOTCH3	2.75e-05	2	183	2	25700162
Pubmed	Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis.	NOTCH1 NOTCH3	2.75e-05	2	183	2	18069660
Pubmed	Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature.	NOTCH1 NOTCH3	2.75e-05	2	183	2	34878922
Pubmed	Reduced display of tumor necrosis factor receptor I at the host cell surface supports infection with Chlamydia trachomatis.	ADAM17 TNFRSF1A	2.75e-05	2	183	2	18167350
Pubmed	A Distinctive Genomic and Immunohistochemical Profile for NOTCH3 and PDGFRB in Myofibroma With Diagnostic and Therapeutic Implications.	PDGFRB NOTCH3	2.75e-05	2	183	2	31566039
Pubmed	Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk.	NOTCH1 NOTCH3	2.75e-05	2	183	2	17881497
Pubmed	ADAM-17 expression is enhanced by FoxM1 and is a poor prognostic sign in gastric carcinoma.	FOXM1 ADAM17	2.75e-05	2	183	2	29180185
Pubmed	The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.	NOTCH1 NOTCH3	2.75e-05	2	183	2	29023469
Pubmed	Nuclear Notch3 expression is associated with tumor recurrence in patients with stage II and III colorectal cancer.	NOTCH1 NOTCH3	2.75e-05	2	183	2	24728738
Pubmed	Combining detection of Notch1 and tumor necrosis factor-α converting enzyme is a reliable biomarker for the diagnosis of abdominal aortic aneurysms.	ADAM17 NOTCH1	2.75e-05	2	183	2	25744398
Pubmed	Glucocorticoids alter the lipid and protein composition of membrane rafts of a murine T cell hybridoma.	PAG1 LAT	2.75e-05	2	183	2	12626544
Pubmed	Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.	NOTCH1 NOTCH3	2.75e-05	2	183	2	14595837
Pubmed	Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors.	NOTCH1 NOTCH3	2.75e-05	2	183	2	16507912
Pubmed	Potential for immunotherapy with heat-killed Mycobacterium vaccae in respiratory medicine.	TNFRSF1A CXCR2	2.75e-05	2	183	2	20635912
Pubmed	SMN Deficiency Destabilizes ABCA1 Expression in Human Fibroblasts: Novel Insights in Pathophysiology of Spinal Muscular Atrophy.	ABCA1 SMN1	2.75e-05	2	183	2	36769246
Pubmed	Tumor necrosis factor-alpha and lymphotoxin-alpha increase macrophage ABCA1 by gene expression and protein stabilization via different receptors.	ABCA1 TNFRSF1A	2.75e-05	2	183	2	19913791
Pubmed	Complex Brugada syndrome inheritance in a family harbouring compound SCN5A and CACNA1C mutations.	CACNA1C SCN5A	2.75e-05	2	183	2	25341504
Pubmed	Distinct roles for Notch1 and Notch3 in human adipose-derived stem/stromal cell adipogenesis.	NOTCH1 NOTCH3	2.75e-05	2	183	2	33021719
Pubmed	A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.	ADAM17 NOTCH1	2.75e-05	2	183	2	10882063
Pubmed	ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1.	FOXM1 ADAM17	2.75e-05	2	183	2	29776401
Pubmed	Association of soluble interleukin-2 receptor α and tumour necrosis factor receptor 1 with heart failure: The Multi-Ethnic Study of Atherosclerosis.	TNFRSF1A IL2RA	2.75e-05	2	183	2	32155316
Pubmed	The exploration of contrasting pathways in Triple Negative Breast Cancer (TNBC).	FOXM1 PPARA	2.75e-05	2	183	2	29301506
Pubmed	The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance.	NOTCH1 NOTCH3	2.75e-05	2	183	2	26634853
Pubmed	Combined Detection of Plasma Tumor Necrosis Factor-α Converting Enzyme and Notch1 is Valuable in Screening Endoleak After Endovascular Abdominal Aortic Aneurysms Repair.	ADAM17 NOTCH1	2.75e-05	2	183	2	33905845
Pubmed	Roles for ADAM17 in TNF-R1 Mediated Cell Death and Survival in Human U937 and Jurkat Cells.	ADAM17 TNFRSF1A	2.75e-05	2	183	2	34831323
Pubmed	Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations.	NOTCH1 NOTCH3	2.75e-05	2	183	2	26563570
Pubmed	A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling.	ADAM17 NOTCH1	2.75e-05	2	183	2	26744411
Pubmed	Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina.	CRX NOTCH1 NOTCH3	5.00e-05	14	183	3	25100656
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TSPOAP1 GON4L CUL9 FAM91A1 USP19 SETD5 MCM3AP CHD6 RAB11FIP4 PLXNB3	6.48e-05	407	183	10	12693553
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	GBF1 NTNG1 ARHGEF18 RNF213 TOGARAM1 BIRC6 PIKFYVE AHRR USF3 PRMT7 MEX3B	6.64e-05	493	183	11	15368895
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CUL9 ARHGEF11 SSPOP TBC1D4 MCM3AP PLXNB3	6.79e-05	130	183	6	12421765
Pubmed	Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro.	NOTCH1 NOTCH3	8.23e-05	3	183	2	15987768
Pubmed	Notch receptor expression in human brain arteriovenous malformations.	NOTCH1 NOTCH3	8.23e-05	3	183	2	25846406
Pubmed	Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress.	DCLRE1A CDC27	8.23e-05	3	183	2	15542852
Pubmed	Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.	NOTCH1 NOTCH3	8.23e-05	3	183	2	27697639
Pubmed	NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.	NOTCH1 NOTCH3	8.23e-05	3	183	2	20801121
Pubmed	Voltage gated ion channels blockade is the underlying mechanism of BIMU8 induced cardiotoxicity.	CACNA1C SCN5A	8.23e-05	3	183	2	28552773
Pubmed	Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.	RIC8B GNAS	8.23e-05	3	183	2	21467038
Pubmed	FoxM1 drives ADAM17/EGFR activation loop to promote mesenchymal transition in glioblastoma.	FOXM1 ADAM17	8.23e-05	3	183	2	29700308
Pubmed	Serum concentration of interleukin 15, interleukin 2 receptor and TNF receptor in patients with polymyositis and dermatomyositis: correlation to disease activity.	TNFRSF1A IL2RA	8.23e-05	3	183	2	21132303
Pubmed	Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.	ADAM17 NOTCH1	8.23e-05	3	183	2	19704010
Pubmed	The WTX/AMER1 gene family: evolution, signature and function.	AMER1 AMER3	8.23e-05	3	183	2	20843316
Pubmed	Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.	NOTCH1 NOTCH3	8.23e-05	3	183	2	7615640
Pubmed	The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.	NOTCH1 NOTCH3	8.23e-05	3	183	2	7918097
Pubmed	Smooth muscle Notch1 mediates neointimal formation after vascular injury.	NOTCH1 NOTCH3	8.23e-05	3	183	2	19433762
Pubmed	KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.	NOTCH1 NOTCH3	8.23e-05	3	183	2	34854382
Pubmed	Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.	NOTCH1 NOTCH3	8.23e-05	3	183	2	29767458
Pubmed	The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.	NOTCH1 NOTCH3	8.23e-05	3	183	2	7698746
Pubmed	A role for cGMP in inducible nitric-oxide synthase (iNOS)-induced tumor necrosis factor (TNF) α-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes.	ADAM17 TNFRSF1A	8.23e-05	3	183	2	22898814
Pubmed	Divergent origins and concerted expansion of two segmental duplications on chromosome 16.	NPIPB3 NPIPB5	8.23e-05	3	183	2	11948212
Pubmed	Hepatitis B virus X protein and hypoxia‑inducible factor-1α stimulate Notch gene expression in liver cancer cells.	NOTCH1 NOTCH3	8.23e-05	3	183	2	27840976
Pubmed	Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells.	NOTCH1 NOTCH3	8.23e-05	3	183	2	33664344
Pubmed	Pseudomonas aeruginosa and sPLA2 IB stimulate ABCA1-mediated phospholipid efflux via ERK-activation of PPARalpha-RXR.	ABCA1 PPARA	8.23e-05	3	183	2	17223797
Pubmed	Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase.	FOXM1 CDC27	8.23e-05	3	183	2	18573889
Pubmed	Complementary and combinatorial patterns of Notch gene family expression during early mouse development.	NOTCH1 NOTCH3	8.23e-05	3	183	2	8645602
Pubmed	Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression.	NOTCH1 NOTCH3	8.23e-05	3	183	2	31346528
Pubmed	Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages.	ADAM17 TNFRSF1A	8.23e-05	3	183	2	17510296
Pubmed	PD-L1 and Notch as novel biomarkers in pancreatic sarcomatoid carcinoma: a pilot study.	NOTCH1 NOTCH3	8.23e-05	3	183	2	34846251
Pubmed	GRO-α/CXCR2 system and ADAM17 correlated expression in Sjögren's syndrome.	ADAM17 CXCR2	8.23e-05	3	183	2	23389772
Pubmed	Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development.	SOX7 NOTCH1	8.23e-05	3	183	2	23818617
Pubmed	Regulation of CXCR2 expression and function by a disintegrin and metalloprotease-17 (ADAM17).	ADAM17 CXCR2	8.23e-05	3	183	2	25412626
Pubmed	Expression patterns of the Wtx/Amer gene family during mouse embryonic development.	AMER1 AMER3	8.23e-05	3	183	2	20503382
Pubmed	Stimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways.	PDGFRB ADAM17	8.23e-05	3	183	2	20529858
Pubmed	SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.	NCOA2 PPARA	8.23e-05	3	183	2	31851938
Pubmed	Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK-SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue.	PPARA PASK	8.23e-05	3	183	2	35011564
Pubmed	The IL-37-Mex3B-Toll-like receptor 3 axis in epithelial cells in patients with eosinophilic chronic rhinosinusitis with nasal polyps.	IL37 MEX3B	8.23e-05	3	183	2	31330219
Pubmed	Up-regulation of ATP binding cassette transporter A1 expression by very low density lipoprotein receptor and apolipoprotein E receptor 2.	ABCA1 LRP8	8.23e-05	3	183	2	22170052
Pubmed	Role of RBM25/LUC7L3 in abnormal cardiac sodium channel splicing regulation in human heart failure.	RBM25 SCN5A	8.23e-05	3	183	2	21859973
Pubmed	Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17.	ADAM17 NOTCH1	8.23e-05	3	183	2	33673337
Pubmed	Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in Mice.	ADAM17 TNFRSF1A	8.23e-05	3	183	2	28062509
Pubmed	Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.	NOTCH1 NOTCH3	8.23e-05	3	183	2	21471519
Pubmed	A dual interaction between the DNA damage response protein MDC1 and the RAG1 subunit of the V(D)J recombinase.	MDC1 CDC27	8.23e-05	3	183	2	22942284
Pubmed	Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.	RIC8B GNAS	8.23e-05	3	183	2	12652642
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	GBF1 TSPOAP1 ARHGEF18 USF3 PLCH2 MDC1 AKAP13 MEX3B NOTCH1 CRTC2	1.02e-04	430	183	10	35044719
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXM1 NCOA2 TACC2 ZNF217 ZNF318 BIRC6 PIKFYVE SOX7 AHRR RNF10 KDM4A DLX4 LBX2	1.06e-04	709	183	13	22988430
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	AMER1 GBF1 PKD1L1 TOGARAM1 ICE1 KANK2 MDC1 AKAP13 MAP3K21	1.35e-04	361	183	9	26167880
Pubmed	The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.	SLC6A18 NCOA2 BHLHA9 SLC5A9 AHRR SLC7A10 NPAS1	1.39e-04	212	183	7	19521566
Interaction	TOP3B interactions	RIN3 GBF1 ZNF628 NLRX1 CUL9 CARD10 ICE1 PPARA ARHGEF11 KANK2 FAAP100 BIRC6 ELAC2 PLEKHM1 PCNX2 PIKFYVE MROH6 ZNF341 SETD5 ZNF408 SURF6 MCM3AP MDC1 SCN5A KBTBD11 ANKRD11 PPP1R9B AKAP13 POLL KDM4A GNAS LRBA MEX3B NOTCH1	1.25e-07	1470	175	34	int:TOP3B
Cytoband	16p11.2	NPIPB12 NPIPB11 PRSS36 LAT NPIPB13 PRSS53	1.29e-04	191	184	6	16p11.2
Coexpression	MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	RIN3 TMEM54 NLRX1 BHLHA9 KCP CUL9 GFRA3 ACTL7B PCNX2 SOX7 ESYT3 AFAP1L2 FOXI2 LBX2 SLC7A10	7.07e-06	544	183	15	M1936
Coexpression	GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_UP	ARHGEF18 ARHGEF11 USP19 UBA7 CIZ1 TENM1 MAP4K2 PLXNB3 TPBG	1.17e-05	199	183	9	M8294
Coexpression	GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN	OTUD1 CUL9 RNF213 ICE1 ZNF217 ZNF318 USP19 UBA7 KBTBD11	1.21e-05	200	183	9	M3579
Coexpression	MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	RIN3 TMEM54 NLRX1 BHLHA9 KCP CUL9 GFRA3 ACTL7B PCNX2 SOX7 ESYT3 AFAP1L2 FOXI2 LBX2 SLC7A10	1.33e-05	574	183	15	MM820
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	RIN3 PDE1B BHLHA9 CARD10 ZNF217 PPARA STIL SOX7 ESYT3 AFAP1L2 DMRT2 HMCN1 KCNC3 SCN5A KCNK6 GNAS MAP3K21 ARHGEF26 SLC7A10 NOTCH1 TPBG	2.12e-05	1074	183	21	M1941
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PAG1 NPIPB4 RNF213 NPIPB5 AKAP12 LRP8 RBM25 TENM1 ANKRD11 LRBA IL2RA	6.70e-10	197	184	11	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Treg\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBTB38 CUL9 RNF213 ZNF831 HOXB2 TBC1D4 LAT TNFRSF8 IL2RA SLC7A10	7.96e-09	192	184	10	b7e08cadb50f66c2efdde45e0fa8bab29367269b
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C PAG1 ZBTB38 PDGFRB KCP AHRR AFAP1L2 DMRT2 NOTCH3	8.14e-08	185	184	9	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NCOA2 ABCA1 NPIPB4 NPIPB3 NPIPB5 BIRC6 ANKRD11 AKAP13 LRBA	1.17e-07	193	184	9	779276e775cb2492e8dd36436295a536084a6415
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	ZCCHC8 TOGARAM1 NPIPB5 TBC1D4 KCNK6 KLHDC4 CRTC2 PSD4	2.77e-07	155	184	8	a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCell	Adult-Mesenchymal-pericyte_cell-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1C COL5A2 PDGFRB KCP CHST1 AFAP1L2 LYPD5 NOTCH3	6.11e-07	172	184	8	858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAG1 SLC5A9 PCDHA8 RAB11FIP4 IL2RA MARCKS NOTCH1 NOTCH3	6.67e-07	174	184	8	b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NPIPB11 RBM25 CSF3R NPIPB13 OTOGL PPP1R9B KCNK6 MARCKS	1.10e-06	186	184	8	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C PAG1 PDGFRB KCP AHRR AFAP1L2 DMRT2 NOTCH3	1.15e-06	187	184	8	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	PAG1 NPIPB4 RNF213 BIRC6 RBM25 ANKRD11 TMEM131L LRBA	1.19e-06	188	184	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAG1 PDGFRB HOXB2 AFAP1L2 GNAS MARCKS NOTCH3 TPBG	1.29e-06	190	184	8	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAG1 PDGFRB SH2D3C HOXB2 AFAP1L2 GNAS MARCKS NOTCH3	1.29e-06	190	184	8	84fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	PAG1 GBF1 RNF213 NPIPB5 BIRC6 TMEM131L LRBA IL2RA	1.35e-06	191	184	8	9454f642c3621370fa23640b631301346b300950
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAG1 PDGFRB HOXB2 AFAP1L2 GNAS MARCKS NOTCH3 TPBG	1.40e-06	192	184	8	063e119c4b58957643908f667e6cfd6f7517fd03
ToppCell	Control-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	CACNA1C COL5A2 PDGFRB SGCA NTNG1 KANK2 AKAP12 HMCN1	1.51e-06	194	184	8	3c2266772c5b56e8e02a461e5193e29588028ee9
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PAG1 PDGFRB DBNDD2 SH2D3C KCP AFAP1L2 NOTCH3 NPAS1	1.76e-06	198	184	8	76d46950c11cb4708866db0da54ce00d5c0adab8
ToppCell	Bronchial-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PAG1 PDGFRB KCP AFAP1L2 DMRT2 NOTCH3	1.83e-06	199	184	8	854628ce91068093c14bd4d45ba38c41469f3549
ToppCell	Bronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PAG1 PDGFRB KCP AFAP1L2 DMRT2 NOTCH3	1.83e-06	199	184	8	929f809579368201331d9099d8904b6e3c41797b
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_C\|E18.5-samps / Age Group, Lineage, Cell class and subclass	PAG1 PDGFRB SGCA DBNDD2 AFAP1L2 C4BPB NOTCH3	3.21e-06	151	184	7	3f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCell	facs-Spleen-nan-24m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 TBC1D2 CARD10 CSF3R HP TNFRSF1A CXCR2	3.98e-06	156	184	7	034d4359359a44c205c6931f38a375271ac2752b
ToppCell	facs-Spleen-nan-24m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 TBC1D2 CARD10 CSF3R HP TNFRSF1A CXCR2	3.98e-06	156	184	7	21267718d3a3dc19988663b6846aed8bb3eae836
ToppCell	facs-Spleen-nan-24m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 TBC1D2 CARD10 CSF3R HP TNFRSF1A CXCR2	3.98e-06	156	184	7	2a4dac4100c0339aad4905b8eaca6e8fe806718b
ToppCell	P07-Endothelial-lymphatic_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADAMTSL1 TBC1D4 LAT SCN5A KBTBD11 GNAS MAP4K2	5.31e-06	163	184	7	5cbab3d03bb1af9391ecad635d6eea1dd42c1337
ToppCell	P07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADAMTSL1 TBC1D4 LAT SCN5A KBTBD11 GNAS MAP4K2	5.31e-06	163	184	7	322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHST1 ZNF831 HMCN1 SCN5A KBTBD11 GNAS MAP4K2	6.23e-06	167	184	7	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHST1 ZNF831 HMCN1 SCN5A KBTBD11 GNAS MAP4K2	6.23e-06	167	184	7	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHST1 ZNF831 HMCN1 SCN5A KBTBD11 GNAS MAP4K2	6.23e-06	167	184	7	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	COVID-19_Moderate-Treg\|COVID-19_Moderate / disease group, cell group and cell class	PAG1 PI16 ZNF831 TBC1D4 LAT HMCN1 IL2RA	6.23e-06	167	184	7	4ddb21421cbe72c06b61dd3a5eb1337e59de42e5
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHST1 ZNF831 HMCN1 SCN5A KBTBD11 GNAS MAP4K2	6.23e-06	167	184	7	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAG1 PDGFRB SLC5A9 IL2RA MARCKS NOTCH1 NOTCH3	7.84e-06	173	184	7	5d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAG1 SLC5A9 PCDHA8 IL2RA MARCKS NOTCH1 NOTCH3	8.14e-06	174	184	7	0fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAG1 PDGFRB SLC5A9 IL2RA MARCKS NOTCH1 NOTCH3	8.14e-06	174	184	7	9eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCell	Healthy_donor-Treg\|Healthy_donor / disease group, cell group and cell class (v2)	PAG1 PI16 ZNF831 AHRR TBC1D4 LAT IL2RA	8.14e-06	174	184	7	1d76921c8404b5be5fbe9f3157d53578033f2ad2
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRB SGCA DBNDD2 SH2D3C KNG1 NOTCH3 NPAS1	8.77e-06	176	184	7	8b5c2fb7e5e551df658b1d5fc7f607a27bab00d5
ToppCell	droplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1B ZNF784 LRP8 RIC8B UBA7 TBC1D4 DCLRE1A	8.77e-06	176	184	7	24b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell	droplet-Marrow-nan-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 PIGQ CSF3R HP TNFRSF1A KLHDC4 CXCR2	9.10e-06	177	184	7	5d70fe2b0592362d664b3b4c84eb450ec2335957
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB KCP SSPOP HOXB2 AFAP1L2 NOTCH3 TPBG	9.10e-06	177	184	7	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB KCP SSPOP HOXB2 AFAP1L2 NOTCH3 TPBG	9.10e-06	177	184	7	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	droplet-Marrow-nan-18m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 PIGQ CSF3R HP TNFRSF1A KLHDC4 CXCR2	9.10e-06	177	184	7	48bcf603ec9593eedd81f3831cf9fde89fad368f
ToppCell	COPD-Stromal-SMC\|World / Disease state, Lineage and Cell class	CACNA1C ADAMTSL1 PDGFRB SGCA KANK2 AKAP12 NOTCH3	9.80e-06	179	184	7	b2709537ec1b46457ab85261f4cdd354e60a8b29
ToppCell	Bronchial_Biopsy-Mesenchymal-Smooth_muscle\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	CACNA1C PDE1B PDGFRB SGCA KANK2 HOXB2 TNFRSF8	1.02e-05	180	184	7	7085a851807e6a833965e1366946db0bbc5174e2
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C COL5A2 PAG1 PDGFRB AFAP1L2 OTOGL NOTCH3	1.05e-05	181	184	7	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CACNA1C ADAMTSL1 PDGFRB SGCA KANK2 OTOGL NOTCH3	1.09e-05	182	184	7	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	CACNA1C COL5A2 PAG1 PDGFRB KCP AFAP1L2 NOTCH3	1.13e-05	183	184	7	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PAG1 PI16 ZNF831 HOXB2 TBC1D4 LAT IL2RA	1.17e-05	184	184	7	300edc4aa3ce55f309005c02c315fa0102ea9da7
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C COL5A2 PAG1 PDGFRB KCP AFAP1L2 NOTCH3	1.17e-05	184	184	7	102b6f621a5b551e622f97b12d787c080b052a72
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PAG1 PI16 ZNF831 HOXB2 TBC1D4 LAT IL2RA	1.17e-05	184	184	7	8b397f9c18ed7abecdbcbd586d0ddadf07cf6e75
ToppCell	Pericytes-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	COL5A2 PDGFRB SGCA CHST1 AKAP12 GASK1A NOTCH3	1.17e-05	184	184	7	3d2d55d0f22874be21665ab37da710482f77fc36
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PNLIPRP2 DMRT3 DMRT2 DLX4 ZNF541 TPBG	1.18e-05	122	184	6	37612ad087d9c11d4a3466244ab36224de31930b
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	PAG1 GBF1 RNF213 NPIPB5 BIRC6 TMEM131L LRBA	1.21e-05	185	184	7	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Treg\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF213 ZNF831 HOXB2 TBC1D4 LAT TNFRSF8 IL2RA	1.21e-05	185	184	7	c1a44b7eed72a673923a7c44d06f891f18aa5aad
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRB DBNDD2 SH2D3C AFAP1L2 GPAT2 NOTCH3 NPAS1	1.26e-05	186	184	7	6568358812f0ca4e0161a1a1b29682fbced35c79
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	PAG1 GBF1 RNF213 NPIPB5 BIRC6 TMEM131L LRBA	1.26e-05	186	184	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	CACNA1C COL5A2 PDGFRB SGCA CHST1 MEX3B NOTCH3	1.26e-05	186	184	7	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ZCCHC8 TOGARAM1 NPIPB5 KCNK6 KLHDC4 CRTC2 PSD4	1.26e-05	186	184	7	76cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL5A2 NPR2 KCP DBN1 AKAP12 RIC8B GASK1A	1.26e-05	186	184	7	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL5A2 NPR2 KCP DBN1 AKAP12 RIC8B GASK1A	1.26e-05	186	184	7	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	Endothelial-G\|World / shred on cell class and cell subclass (v4)	ABCA1 ADAMTSL1 TBC1D4 MROH6 GNAS MAP4K2	1.29e-05	124	184	6	4b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	CACNA1C COL5A2 PAG1 PDGFRB KCP AFAP1L2 NOTCH3	1.30e-05	187	184	7	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAG1 PDGFRB HOXB2 AFAP1L2 GNAS MARCKS NOTCH3	1.35e-05	188	184	7	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAG1 PDGFRB HOXB2 AFAP1L2 GNAS MARCKS NOTCH3	1.39e-05	189	184	7	26cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PAG1 PDGFRB SH2D3C CHST1 AFAP1L2 HMCN1 NOTCH3	1.39e-05	189	184	7	9c2492c38f27e4c699b40680652e4c64911cce52
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	CACNA1C PAG1 PDGFRB KCP AFAP1L2 DMRT2 NOTCH3	1.39e-05	189	184	7	d7ed96add29f219183c802895fbff519b627f635
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAG1 PDGFRB HOXB2 AFAP1L2 GNAS MARCKS NOTCH3	1.44e-05	190	184	7	2ab604d35456beba71c25511e0f819000e6642d2
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAG1 PDGFRB SH2D3C AFAP1L2 GNAS MARCKS NOTCH3	1.44e-05	190	184	7	106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAG1 PDGFRB HOXB2 AFAP1L2 GNAS MARCKS NOTCH3	1.44e-05	190	184	7	951e067d14412db67dc3babcdf61e41717d7b429
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C PDE1B PDGFRB SGCA TMEM131L GPAT2 NOTCH3	1.49e-05	191	184	7	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	normal_Lymph_Node-T/NK_cells-Treg\|normal_Lymph_Node / Location, Cell class and cell subclass	CUL9 HOXB2 TBC1D4 LAT TNFRSF8 IL2RA SLC7A10	1.54e-05	192	184	7	d2c2a98d331522a3ab7973bfaf4396ef4d684888
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|lung / Disease (COVID-19 only), tissue and cell type	CACNA1C COL5A2 PAG1 ADAMTSL1 PDGFRB AFAP1L2 NOTCH3	1.65e-05	194	184	7	5e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	CACNA1C COL5A2 PDGFRB SGCA NTNG1 KANK2 HMCN1	1.71e-05	195	184	7	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RNF213 ZNF831 PASK HOXB2 TBC1D4 LAT IL2RA	1.71e-05	195	184	7	7b181e5b05becec3fd5031849affa9a135b26d3f
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRB SGCA DBNDD2 SH2D3C AFAP1L2 GPAT2 NOTCH3	1.71e-05	195	184	7	815ac5dacd382b11abb32011ed1c0635b0ddc779
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 ADAMTSL1 PDGFRB PI16 DBN1 AKAP12 GASK1A	1.71e-05	195	184	7	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_4\|COVID-19_Mild / Disease condition and Cell class	ABCA1 RNF213 FAM91A1 RBM25 CSF3R ADAM17 MARCKS	1.76e-05	196	184	7	3729d1444c65cad640377894decc64129bc3fd5b
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRB DBNDD2 SH2D3C AFAP1L2 GPAT2 MARCKS NOTCH3	1.76e-05	196	184	7	c16fbd23d9e117831b55ab3da5b08b22dd972432
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CACNA1C COL5A2 PDGFRB NTNG1 KANK2 HOXB2 MARCKS	1.82e-05	197	184	7	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C PDGFRB SGCA KANK2 AKAP12 PRSS53 OTOGL	1.82e-05	197	184	7	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PAG1 PDGFRB DBNDD2 SH2D3C AFAP1L2 NOTCH3 NPAS1	1.88e-05	198	184	7	72aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCell	Control-Control-Lymphocyte-T/NK-Treg\|Control / Disease, condition lineage and cell class	PAG1 PI16 ZNF831 HOXB2 TBC1D4 LAT IL2RA	1.94e-05	199	184	7	6b7eb14bf03aa05f2d4ac4f5dd1ccf41a7e47bd1
ToppCell	Caecum-(1)_T_cell-(15)_Treg\|Caecum / shred on region, Cell_type, and subtype	RNF213 ZNF831 PASK TBC1D4 LAT IL2RA SLC7A10	1.94e-05	199	184	7	12c22b07a231c9dc548e9dc37e0a60296a4a6273
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 ADAMTSL1 PDGFRB PI16 DBN1 AKAP12 GASK1A	1.94e-05	199	184	7	993fa050a095017135a6e723c77cd38b9d782e58
ToppCell	distal-mesenchymal-Pericyte-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PAG1 PDGFRB SGCA KCP AFAP1L2 DMRT2 NOTCH3	1.94e-05	199	184	7	000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NPIPB4 RNF213 NPIPB5 RBM25 TENM1 ANKRD11 LRBA	1.94e-05	199	184	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Caecum-T_cell-Treg\|Caecum / Region, Cell class and subclass	RNF213 ZNF831 PASK TBC1D4 LAT IL2RA SLC7A10	1.94e-05	199	184	7	ab0b32c077ac26d32a293dcf686af6984980793f
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PDGFRB SGCA KANK2 AKAP12 NOTCH3	1.94e-05	199	184	7	20f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 ADAMTSL1 PDGFRB PI16 DBN1 AKAP12 GASK1A	1.94e-05	199	184	7	f835e7ffe976843b0edbf695762d463da85793f3
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PDGFRB SGCA KANK2 AKAP12 NOTCH3	1.94e-05	199	184	7	7c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCell	Bronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PDGFRB SGCA KANK2 AFAP1L2 NOTCH3	2.01e-05	200	184	7	12326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCell	Bronchial-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A2 PDGFRB PI16 SGCA KANK2 AKAP12 GASK1A	2.01e-05	200	184	7	5ea12e17f50fefbf5534e487af3392b2fa2d13ad
ToppCell	3'-Parenchyma_lung-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 PDGFRB PI16 SGCA KANK2 AKAP12 GASK1A	2.01e-05	200	184	7	ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PDGFRB PI16 AKAP12 HMCN1 TENM1	2.01e-05	200	184	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Bronchial-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PDGFRB SGCA KANK2 AFAP1L2 NOTCH3	2.01e-05	200	184	7	362706445edb33b313684efe50b1f44f5f816e67
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PDGFRB SGCA NTNG1 KANK2 HMCN1	2.01e-05	200	184	7	cb31cfcfa8e6d6cc610c4c22e97bc009dd8a9e7c
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	COL5A2 PAG1 ZBTB38 PDGFRB KCP AFAP1L2 NOTCH3	2.01e-05	200	184	7	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	Lung_Parenchyma-Control-Mesenchymal\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL5A2 PDGFRB PI16 DBN1 KANK2 AKAP12 GASK1A	2.01e-05	200	184	7	1e75d1302c22e1b1666c19c0c9259d5cc8be16d5
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A2 ABCA1 ADAMTSL1 PDGFRB PI16 AKAP12 TENM1	2.01e-05	200	184	7	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	COL5A2 PAG1 PDGFRB KCP AFAP1L2 OTOGL NOTCH3	2.01e-05	200	184	7	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	cellseq2-Mesenchymal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 PDGFRB SGCA DBNDD2 KANK2 AKAP12 NOTCH3	2.01e-05	200	184	7	6b558cce0d6047c7e85f428adff80c5ca3084ea4
ToppCell	Parenchymal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL5A2 PDGFRB SGCA KANK2 HMCN1 NOTCH3	2.01e-05	200	184	7	2e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell	Parenchyma_Control_(B.)-Stromal-TX\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	COL5A2 PDGFRB PI16 DBN1 KANK2 AKAP12 GASK1A	2.01e-05	200	184	7	0a86656d48e4238d0e4d592d477d29f7ba7c2ec0
Disease	Schizophrenia	CACNA1C PAG1 ABCA1 PDGFRB NTNG1 PPARA DBN1 ARHGEF11 GFRA3 LRP8 HP PPP1R9B GNAS TNFRSF1A IL2RA SLC7A10 NPAS1	2.03e-05	883	174	17	C0036341
Disease	infantile myofibromatosis (is_implicated_in)	PDGFRB NOTCH3	3.46e-05	2	174	2	DOID:0080109 (is_implicated_in)
Disease	Myofibromatosis	PDGFRB NOTCH3	3.46e-05	2	174	2	C0206648
Disease	Infantile myofibromatosis	PDGFRB NOTCH3	3.46e-05	2	174	2	cv:C0432284
Disease	Myofibromatosis	PDGFRB NOTCH3	3.46e-05	2	174	2	cv:C0206648
Disease	Infantile myofibromatosis	PDGFRB NOTCH3	3.46e-05	2	174	2	C0432284
Disease	Hypertensive disease	SLC6A18 CACNA1C PPARA HP GNAS KNG1 CXCR2	1.41e-04	190	174	7	C0020538
Disease	neutrophil percentage of leukocytes	RIN3 ZBTB38 TSPOAP1 SH2D3C ARHGEF18 ZNF831 CSF3R AKAP13 TNFRSF1A IL2RA SLC7A10 CXCR2	2.87e-04	610	174	12	EFO_0007990
Disease	sciatic neuropathy (biomarker_via_orthology)	PDGFRB DBN1 GFRA3 AKAP12 TNFRSF1A	3.08e-04	99	174	5	DOID:11446 (biomarker_via_orthology)
Disease	alkaline phosphatase measurement	NCOA2 RIN3 ADAMTSL1 KCP NTNG1 ZNF318 PPARA PLEKHM1 SURF6 RP1L1 RECQL4 RNF10 AKAP13 LRBA MAP4K2 NOTCH1	3.55e-04	1015	174	16	EFO_0004533
Disease	Allergic Reaction	HP TNFRSF1A KNG1 CXCR2	5.31e-04	63	174	4	C1527304
Disease	Eczema	RIN3 ZBTB38 IL37 ZNF217 GFRA3 TNFRSF8 IL2RA SLC7A10	5.33e-04	310	174	8	HP_0000964
Disease	Hypersensitivity	HP TNFRSF1A KNG1 CXCR2	5.63e-04	64	174	4	C0020517
Disease	Malignant neoplasm of breast	FOXM1 NCOA2 RPS6KB2 TACC2 ZNF318 DBN1 AKAP12 CRX HP OTOGL TENM1 LRBA CDC27 NOTCH1 NOTCH3 ZNF541	6.53e-04	1074	174	16	C0006142
Disease	cancer antigen 15.3 measurement	GON4L MSTO1	7.12e-04	7	174	2	EFO_0010585
Disease	Precocious Puberty	MKRN3 GNAS	7.12e-04	7	174	2	C0034013
Disease	Cryptogenic sexual precocity	MKRN3 GNAS	7.12e-04	7	174	2	C0271527
Disease	adenocarcinoma (implicated_via_orthology)	NOTCH1 NOTCH3	7.12e-04	7	174	2	DOID:299 (implicated_via_orthology)
Disease	central nervous system cancer (implicated_via_orthology)	NOTCH1 NOTCH3	7.12e-04	7	174	2	DOID:3620 (implicated_via_orthology)
Disease	Central Precocious Puberty	MKRN3 GNAS	7.12e-04	7	174	2	C0342543
Disease	visceral:subcutaneous adipose tissue ratio	CAAP1 ELAC2 ADAM17 SLC7A10	7.91e-04	70	174	4	EFO_0004767
Disease	intestinal cancer (implicated_via_orthology)	SOX7 NOTCH1 NOTCH3	8.81e-04	32	174	3	DOID:10155 (implicated_via_orthology)
Disease	Brugada syndrome	CACNA1C SCN5A	9.46e-04	8	174	2	cv:C1142166
Disease	mannose measurement	SLC5A9 FOXI2	9.46e-04	8	174	2	EFO_0006958
Disease	Testotoxicosis	MKRN3 GNAS	9.46e-04	8	174	2	C1504412
Disease	helix rolling	SOWAHC LRBA	9.46e-04	8	174	2	EFO_0007670
Disease	cortical surface area measurement	NCOA2 COL5A2 NPR2 RIN3 ADAMTSL1 SGCA CUL9 ELAC2 PLEKHM1 LRP8 PIGQ LRRIQ1 DMRT3 DMRT2 RP1L1 MDC1 PPP1R9B RAB11FIP4	1.04e-03	1345	174	18	EFO_0010736
Disease	response to 4'-epidoxorubicin, response to antineoplastic agent	ICE1 TNFRSF1A	1.21e-03	9	174	2	GO_0097327, GO_1902522
Disease	response to sulfasalazine, Drug-induced agranulocytosis	TSPOAP1 MROH6 GNAS	1.35e-03	37	174	3	EFO_0008324, HP_0012235
Disease	monocyte percentage of leukocytes	PAG1 PDGFRB TSPOAP1 SH2D3C ARHGEF11 CSF3R MCM3AP AKAP13 GPAT2 SLC7A10 MARCKS CXCR2	1.39e-03	731	174	12	EFO_0007989
Disease	Anemia, Sickle Cell	CACNA1C HP	1.51e-03	10	174	2	C0002895
Disease	Reactive hypoglycemia	CACNA1C PPARA	1.51e-03	10	174	2	C0271710
Disease	Fasting Hypoglycemia	CACNA1C PPARA	1.51e-03	10	174	2	C0271708
Disease	temporomandibular joint disorder	SGCA PPP1R9B	1.51e-03	10	174	2	EFO_0005279
Disease	blood urea nitrogen measurement	PAG1 KCP GON4L ZNF318 AKAP13 GNAS LRBA ARHGEF26 PSD4	1.52e-03	452	174	9	EFO_0004741
Disease	Calcium channel blocker use measurement	CACNA1C ARHGEF18 RNF213 ZNF318 ZNF831 GNAS	1.71e-03	213	174	6	EFO_0009930
Disease	Eczema, allergic rhinitis	ZBTB38 ZNF217 GFRA3 TNFRSF8 IL2RA SLC7A10	1.79e-03	215	174	6	EFO_0005854, HP_0000964
Disease	Hypoglycemia	CACNA1C PPARA	1.84e-03	11	174	2	C0020615
Disease	attention function measurement	NCOA2 CAAP1 ZNF831 LRBA IL2RA	1.89e-03	148	174	5	EFO_0007636
Disease	ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis	KCP ZNF831 RIC8B TNFRSF1A IL2RA NOTCH1 CXCR2	1.91e-03	295	174	7	EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Disease	lymphocyte percentage of leukocytes	RIN3 ZBTB38 GBF1 TSPOAP1 ARHGEF18 ZNF831 CSF3R TNFRSF1A IL2RA SLC7A10 CXCR2	2.06e-03	665	174	11	EFO_0007993
Disease	Tinnitus, wellbeing measurement	MAP3K8 ELAC2 AAR2 FOXI2	2.55e-03	96	174	4	EFO_0007869, HP_0000360
Disease	chronic obstructive pulmonary disease (is_marker_for)	MUC5B HP TNFRSF1A CXCR2	2.64e-03	97	174	4	DOID:3083 (is_marker_for)
Disease	cystatin C measurement	OTUD1 KCP ATF6B HOXB2 ANKRD11 GNAS ARHGEF26 KNG1	2.76e-03	402	174	8	EFO_0004617
Disease	multiple sclerosis	NCOA2 ADAMTSL1 ZBTB38 TSPOAP1 KCP AKAP13 TNFRSF1A IL2RA SLC7A10 MARCKS	2.88e-03	594	174	10	MONDO_0005301
Disease	Impaired cognition	CACNA1C NOTCH3	3.00e-03	14	174	2	C0338656
Disease	suntan	AAR2 MROH8 ZNF341 ANKRD11	3.28e-03	103	174	4	EFO_0004279
Disease	Retinitis Pigmentosa	ARHGEF18 CRX ZNF408 FOXI2	3.40e-03	104	174	4	C0035334
Disease	hair colour measurement	RIN3 ZBTB38 SNX16 ZNF831 AKAP12 ZNF750 ANKRD11 AKAP13 ARHGEF26 KLHDC4	3.68e-03	615	174	10	EFO_0007822
Disease	neutrophil measurement	ZBTB38 TSPOAP1 MROH6 TMEM131L SLC7A10	4.08e-03	177	174	5	EFO_0803548
Disease	leukemia	FOXM1 CSF3R HP	4.22e-03	55	174	3	C0023418
Disease	1-Methylhistidine measurement	NCOA2 OTOGL	4.44e-03	17	174	2	EFO_0021543
Disease	idiopathic pulmonary fibrosis	MUC5B ZNF318 AKAP13	4.67e-03	57	174	3	EFO_0000768
Disease	Tachycardia	GNAS KNG1	4.97e-03	18	174	2	C0039231
Disease	Tachyarrhythmia	GNAS KNG1	4.97e-03	18	174	2	C0080203
Disease	autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease	PRSS36 IL2RA	4.97e-03	18	174	2	EFO_0003779, EFO_0004237, EFO_0006812
Disease	body surface area	ZBTB38 PPARA GFRA3 SETD5 ANKRD11 AKAP13 GNAS ARHGEF26 TPBG PSD4	5.01e-03	643	174	10	EFO_0022196
Disease	granulocyte percentage of myeloid white cells	PDGFRB TSPOAP1 SH2D3C CSF3R SLC7A10 CXCR2	5.28e-03	268	174	6	EFO_0007997
Disease	inflammatory bowel disease (is_implicated_in)	IL37 ADAM17	5.53e-03	19	174	2	DOID:0050589 (is_implicated_in)
Disease	ovulation	PLEKHM1 KDM4A	5.53e-03	19	174	2	GO_0030728
Disease	birth weight, parental genotype effect measurement	ZBTB38 USF3 AKAP13 ADAM17 MAP4K2	5.73e-03	192	174	5	EFO_0004344, EFO_0005939

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCEPIGSPEDAQDLP	PI16	196	Q6UXB8
ACLEPTDGLPQSEPP	AHRR	621	A9YTQ3
EGPLGPSPDDDLCVS	AMER3	431	Q8N944
DLPCPPDPASDTKDV	ESYT3	626	A0FGR9
PAGDSPDQLLLEPCA	CARD10	811	Q9BWT7
ESCPDEEEGPFSLPE	ARHGEF18	786	Q6ZSZ5
LLCPGDSPAVAAAPE	ACTL7B	361	Q9Y614
SLPEAPLDVAPEPAC	ANKRD11	2071	Q6UB99
LPCPEGLDPDTDDAP	BIRC6	4811	Q9NR09
EEEENGPCPPSLLPA	SLC7A10	501	Q9NS82
SLEGSPPPCLGQEEA	AKAP12	1391	Q02952
AEDSAEDLGGPCPEP	BHLHA9	16	Q7RTU4
LELEEAPEPSCRCPG	C2orf27A	41	P0DPF5
PLEPTQDGSAIETCP	EFL1	461	Q7Z2Z2
GNPIPDTPCQAGEEE	ABCA1	1421	O95477
EPEDCAPVVVELPEG	AAR2	366	Q9Y312
DPSSAPETDGQFLPC	AKAP13	306	Q12802
LSLVGCEVVPDPSPD	AFAP1L2	396	Q8N4X5
ELGPCPEDGSDAPLE	ARHGEF11	1496	O15085
GPTVPLSCAPVEESD	CLDN25	201	C9JDP6
PDDSLENSPPGDDCL	AMER1	511	Q5JTC6
NAPAPCTPEEDLTGL	ARHGEF26	151	Q96DR7
APPSDNPPCAFDLDD	NPR2	431	P20594
IPACPEEEPLLDNST	CCDC144CP	261	Q8IYA2
IEGPCNEEAAAPEAP	CAAP1	266	Q9H8G2
PLCGPAEHPQELEAD	DLX4	81	Q92988
TSLEGDCEPSPAPAV	POLL	221	Q9UGP5
DPLPLPAGNCTDEEG	MUC5B	246	Q9HC84
PECVLTPLPPSADDN	NPIPB3	286	Q92617
ECVLTPLPPSADDNL	NPIPB3	306	Q92617
ESPCGIIIPHENSPD	RBM25	641	P49756
DPPAPCSQEEAGAAV	TSPOAP1	1146	O95153
PCAPEIPDCVEQGSE	RAB11FIP4	101	Q86YS3
CEEASSPGPEPTEPE	NPAS1	426	Q99742
PECVLTPLPPSADDN	NPIPB12	286	F8W0I5
LPSGCPEAEEPANLE	KASH5	131	Q8N6L0
LPPPCPASFNADEDD	KCNK6	271	Q9Y257
DPHLGTPSPEDCELE	MAP4K2	291	Q12851
PEPETGECQPAAAAE	OTUD1	46	Q5VV17
LDAGPEDTCPSAEEP	PASK	851	Q96RG2
AFSPCLPPDLGSVDV	PCDHA8	771	Q9Y5H6
AGRDIPPPLIEEACE	NOTCH1	1436	P46531
QESPDACLPPTVPEA	MDC1	1031	Q14676
TDIADDGCPKPPEIA	HP	26	P00738
TPVSLPPEPACEDAD	LAT	136	O43561
PISDDSCIAVPPLEG	FAM91A1	226	Q658Y4
EECGVEPDAPLSSLP	MCM3AP	1016	O60318
EAPALEPPSAACLDL	FOXI2	216	Q6ZQN5
DLPIDECEGPKPASQ	ADAMTSL1	561	Q8N6G6
QAPPLEDIADDCSPG	MAP3K8	346	P41279
ADIPASPCGEPEEEV	GPATCH3	266	Q96I76
HLSEPCEPPDATEQG	PCNX2	2081	A6NKB5
LCPAPSIDAVEPLTG	PLXNB3	831	Q9ULL4
TDSKEPPGELCPDVL	MSTO1	36	Q9BUK6
DELSPCEEEAPPSPA	PDE1B	511	Q01064
ACLPAELTFGPADAP	PEAK3	106	Q6ZS72
PFLLDAAPCEPESLE	CXCR2	31	P25025
RCEAPAAAPEVSEEP	NOTCH3	1371	Q9UM47
ESELPPRAGNEEECP	KDM4A	356	O75164
DGVTVDPALLPPACL	LRBA	1691	P50851
PECVLTPLPPSADDN	NPIPB5	286	A8MRT5
ECVLTPLPPSADDNL	NPIPB5	306	A8MRT5
EPCSLNSALEPAPEG	MROH6	81	A6NGR9
GCATLLNFDELPEPP	DBN1	526	Q16643
LNFDELPEPPATFCD	DBN1	531	Q16643
TGLCSDPEEPQEPAA	NLRX1	256	Q86UT6
CAGTALSDDPEGPPV	NRSN2	36	Q9GZP1
VPAEPPEACGELSNG	PRADC1	66	Q9BSG0
ESGPGPTSPLCALEE	LBX2	36	Q6XYB7
TDLDIPDIPGLHCEP	MROH8	46	Q9H579
PECVLTPLPPSADDN	NPIPB4	286	C9JG80
ECVLTPLPPSADDNL	NPIPB4	306	C9JG80
EGELPPDLTENTCPS	RBM12B-AS1	86	Q9P1G2
DPFLDECPSDVLPEQ	FAAP100	621	Q0VG06
SCAREGEPDSPDIPE	LRRIQ1	1251	Q96JM4
ITLSCEADGLPPPDI	HMCN1	4096	Q96RW7
EPACPGALEDICDPA	HOXB2	211	P14652
PECLLTPLPPSADDN	NPIPB11	286	E5RHQ5
EEPEDLDCGRPEPSA	PRSS36	31	Q5K4E3
DIPPESLPCDDSSLL	PIKFYVE	916	Q9Y2I7
GFEPEPSDPCVEERL	GASK1A	441	Q9UFP1
EPQCCLEDPAGSPLE	IL37	21	Q9NZH6
EDLPEPVEPSALCSD	ICE1	1361	Q9Y2F5
DVPAEDDPSPCALET	CACNA1C	306	Q13936
ELEEDVCGAPRSTPP	DMRT2	21	Q9Y5R5
PSEEPSVPADCLEAA	GFRA3	76	O60609
VEPATPEEGEPATQC	GAGE12B;	36	A1L429
VEPATPEEGEPATQC	GAGE12H	36	A6NDE8
PECTLSTGLLEPADP	PRMT7	621	Q9NVM4
GDENCAEPSAPLPAE	CHD6	2681	Q8TD26
IDLGDPDAADVFLPC	DBNDD2	166	Q9BQY9
EDPRISIPDDGCPFV	DMRT3	431	Q9NQL9
LSDPCALLPDPAVEE	CRTC2	671	Q53ET0
PDAPCDIDHASAPLG	GPAT2	336	Q6NUI2
EHSPGPPLADAECQE	GON4L	1266	Q3T8J9
IPACPEEEPLLDNST	CCDC144B	311	Q3MJ40
SASDAEHCPELPPVD	C4BPB	16	P20851
CQDVLDCADPVTPPG	COL5A2	76	P05997
VTPAPSQEDDCVFGP	CSF3R	801	Q99062
EAQPECSPEAPPAEA	MARCKS	316	P29966
AELCDDDPPEIPHAT	IL2RA	21	P01589
DLVPASLPCEELAEP	FBXO41	121	Q8TF61
SLPCEELAEPGLVPA	FBXO41	126	Q8TF61
LSQAPDPPTLSGAEC	LYPD5	121	Q6UWN5
LPPCVDEPELLFSEG	FOXM1	551	Q08050
PPEIPSELGACDFEK	GBF1	1756	Q92538
SELCLDLPDPPEDPV	KANK2	246	Q63ZY3
EDSLEEAGSPAPGPC	KLHDC4	416	Q8TBB5
GCPRDIPTNSPELEE	KNG1	266	P01042
PVCVSPLGCDDDLPS	CUL9	2071	Q8IWT3
DSPPRSETECPDGLL	DCLRE1A	146	Q6PJP8
IPACPEEEPLLDNST	CCDC144A	311	A2RUR9
PFESLCEIGEKPDPD	CDC27	151	P30260
EDSIPTCSPEVGGPE	PKD1L1	2401	Q8TDX9
RPSTDVCPDPLGISD	CRX	126	O43186
PAGPCFQDEPEEVRL	PNLIPRP2	196	P54317
CLGETREPEDPAPAL	LRP8	906	Q14114
GSIIPIEPDCDEEPT	OTOGL	1896	Q3ZCN5
EPEPELEQLPDSGCP	PDGFRB	1081	P09619
PECVLTPLPPSADDN	NPIPB13	286	A6NJU9
EDCSSALPTDQPPLG	RIN3	241	Q8TB24
SPLCPLSPLEAGDLE	PPARA	6	Q07869
GEASVPSPDGCPELQ	MEX3B	346	Q6ZN04
ECDASTPELAHPPEL	NTNG1	91	Q9Y2I2
EPPEAPQGCLSPSDL	PLEKHM1	646	Q9Y4G2
PEGLECPALDAELSD	SOX7	11	Q9BT81
CPALDAELSDGQSPP	SOX7	16	Q9BT81
PTPLCSGPEAEEEPC	SSPOP	3231	A2VEC9
SCPSLPAGPTGVEED	TMEM131L	1386	A2VDJ0
EGEGEPELSPADACP	RPS6KB2	16	Q9UBS0
PGSCEEPKLSPDGLE	MAP3K21	641	Q5TCX8
GPPLSPQETDCAIEA	RIC8B	216	Q9NVN3
CPRPASEEDTDAVGP	RECQL4	416	O94761
ASGETLPDPLDPTCS	KCP	851	Q6ZWJ8
NEPIPVENDGEACGP	GNAS	56	Q5JWF2
LAVGVEGPCQDEPPS	PIGQ	696	Q9BRB3
LGPAPSAAPCVDEAL	PSD4	356	Q8NDX1
AEPQAPGCGETPEDS	SCN5A	1121	Q14524
PSPVEERCGDSPNSE	SETD5	71	Q9C0A6
ESTPEISERPAGECP	SLC5A9	581	Q2M3M2
GPECDVPEEQCIDPT	TENM1	586	Q9UKZ4
PPPICPDSLDDADAL	SMN1	246	Q16637
GPSEDLELPPHGCEE	SOWAHC	171	Q53LP3
VEATPEGACTEPREP	SURF6	181	O75683
LGNSCDPEEEAPPPV	PAG1	246	Q9NWQ8
ASPEELASPEERACP	KBTBD11	86	O94819
LASPEERACPEEPAA	KBTBD11	91	O94819
LAGLPPSEELADPCS	POM121L2	141	Q96KW2
CPPTEAPDRDFLVDA	SGCA	276	Q16586
EPDPAACDLGDERPK	SLC6A18	6	Q96N87
PPPGNAEDDTVCLDL	ADAM17	556	P78536
TESLAPPLCLLGDDP	ATF6B	126	Q99941
PPLCLLGDDPTSSFE	ATF6B	131	Q99941
CDPPGPADLVLEEGD	CHST1	166	O43916
ALVGPDDVEFCSPPA	CNMD	11	O75829
APEPEPCEASELPAK	CIZ1	246	Q9ULV3
DDLLCPHPAAESPSD	NCOA2	1061	Q15596
AEEPEPEAEPGSCLA	PRSS53	531	Q2L4Q9
HPLLEDGCIEDDPAP	RNF213	2861	Q63HN8
PTGPGEEAPDACAVD	ZNF750	611	Q32MQ0
PDDGPCLLSVPDQCV	WFDC5	36	Q8TCV5
DPGREVPECLEITPT	STIL	101	Q15468
ACEDPHDLLATPTPE	USP19	101	O94966
PPAIQPLDDEDVFLC	ZNF341	41	Q9BYN7
SSPCPNELDLPVPEG	ZCCHC8	556	Q6NZY4
GEDCESPAPEADRPH	UCK1	6	Q9HA47
SELLALAPDCPFDPT	TMEM54	136	Q969K7
ILAEELCTPPDPGAA	ELAC2	291	Q9BQ52
DLPVCEPSGESAAPD	MKRN3	31	Q13064
SASAEPCPAEGTEEP	RP1L1	1436	Q8IWN7
ALDCLPEDGELLPSP	UBA7	391	P41226
PEDGELLPSPEDCAL	UBA7	396	P41226
CSLETIAEEPAPGPG	PLCH2	1001	O75038
SEPEPEGLPEACDDL	RNF10	456	Q8N5U6
ASPGEDAAEPCIDPG	ZNF408	206	Q9H9D4
DAAEPCIDPGSQSPS	ZNF408	211	Q9H9D4
DTTFEAPPLGTQPDC	TNFRSF8	321	P28908
PEQETEPPLGSCSDV	TNFRSF8	561	P28908
SAEPPCNDGLLESFP	USF3	831	Q68DE3
GEAPPCQPDSVALLD	TACC2	1041	O95359
EVVVPGSPGDCLPEE	TBC1D4	256	O60343
ACEEAAPAGVLPELP	ZSCAN18	291	Q8TBC5
QPGTCSPDLAAPLDE	ZNF217	416	O75362
TLLECDSAPPEGPEP	SH2D3C	751	Q8N5H7
ELNSADLDCDPILPP	TPBG	336	Q13641
PEPSGDSPLGLCQSE	ZBTB38	881	Q8NAP3
EASGFPEDPLPCAVT	TOGARAM1	326	Q9Y4F4
PSPGEADSILEDPSC	ZNF831	996	Q5JPB2
LCLDDPPGPFDSLEE	SNX16	211	P57768
TDTQEAECAGPPVPD	TTC1	21	Q99614
DIEEALCGPAALPPA	TNFRSF1A	436	P19438
PIGCNSSDPADFEPI	ZNF318	2051	Q5VUA4
QVPPPEEESGDCARS	TBC1D2	26	Q9BYX2
LKEAPPEEEACGDSP	ZNF541	226	Q9H0D2
APAALDTELPEEPCL	ZNF541	326	Q9H0D2
SEELLLEHQPCPGPD	ZNF628	306	Q5EBL2
DDCRPGTPPSDLIEI	ZNF784	31	Q8NCA9
APGEPCPLAQEEVIE	KCNC3	641	Q14003
CVEIPGLSEEEDPAP	PPP1R9B	431	Q96SB3