Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

DCHS2 PADI4 CDH26 DGKA CDH23 ADGRV1 ADGRE2 DYSF ITPR3 ESYT2 NELL2 SULF2 HMCN2 OTOF SULF1 PCDHGB1 PCDHGA9 PLCD4 PCDHA5 SYT2 MYOF TGM3 PDP1 MACF1 PCDHGC3

3.26e-0774920925GO:0005509
GeneOntologyMolecularFunctionATP hydrolysis activity

RTEL1 PEX1 ABCA10 IQCA1L MDN1 SHOC1 NAV1 DNAH8 HSPA2 HSPA8 ABCC10 ATP13A4 DNAH3 KIF16B ABCA6 MACF1

1.75e-0544120916GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

RTEL1 TMEM94 PEX1 ABCA10 IQCA1L MDN1 SHOC1 NAV1 DNAH8 HSPA2 HSPA8 ABCC10 ATP13A4 DNAH3 KIF16B ABCA6 MACF1 MYO15A

8.60e-0561420918GO:0140657
GeneOntologyMolecularFunctionN-acetylglucosamine-6-sulfatase activity

SULF2 SULF1

3.25e-0432092GO:0008449
GeneOntologyMolecularFunctionalkylglycerol kinase activity

DGKA DGKQ

3.25e-0432092GO:0047649
GeneOntologyCellularComponentextracellular matrix

TPSAB1 FREM2 SERPINB9 HMCN2 SULF1 ADAMTS16 SERPINF2 GP1BA FRAS1 VASN L1CAM LAMA4 LAMB3 FREM3 ITIH5 TGM3 ADAMTS14 TPSB2

1.12e-0465620918GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

TPSAB1 FREM2 SERPINB9 HMCN2 SULF1 ADAMTS16 SERPINF2 GP1BA FRAS1 VASN L1CAM LAMA4 LAMB3 FREM3 ITIH5 TGM3 ADAMTS14 TPSB2

1.16e-0465820918GO:0030312
DomainCalx_beta

ADGRV1 FREM2 FRAS1 FREM3

8.81e-0782014SM00237
DomainCalx_beta

ADGRV1 FREM2 FRAS1 FREM3

1.57e-0692014IPR003644
DomainCalx-beta

ADGRV1 FREM2 FRAS1 FREM3

1.57e-0692014PF03160
DomainCadherin

DCHS2 CDH26 CDH23 FREM2 PCDHGB1 PCDHGA9 PCDHA5 FREM3 PCDHGC3

5.26e-061182019IPR002126
DomainFerI

DYSF OTOF MYOF

1.21e-0552013SM01202
DomainFerB

DYSF OTOF MYOF

1.21e-0552013SM01201
DomainFerlin_B-domain

DYSF OTOF MYOF

1.21e-0552013IPR012561
DomainFerlin_C

DYSF OTOF MYOF

1.21e-0552013PF16165
DomainFerlin_C

DYSF OTOF MYOF

1.21e-0552013IPR032362
DomainFerIin_dom

DYSF OTOF MYOF

1.21e-0552013IPR012968
DomainFerI

DYSF OTOF MYOF

1.21e-0552013PF08151
DomainFerB

DYSF OTOF MYOF

1.21e-0552013PF08150
DomainCA

DCHS2 CDH26 CDH23 FREM2 PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

3.46e-051152018SM00112
DomainExtracellular_sulfatase

SULF2 SULF1

1.15e-0422012IPR014615
DomainExtracellular_sulfatase_C

SULF2 SULF1

1.15e-0422012IPR024609
DomainDUF3740

SULF2 SULF1

1.15e-0422012PF12548
DomainHEAT

UTP20 PPP4R1 SCYL3 PRKDC HTT

1.61e-04482015PF02985
DomainAAA

PEX1 ABCA10 MDN1 NAV1 DNAH8 ABCC10 DNAH3 ABCA6

1.69e-041442018SM00382
DomainAAA+_ATPase

PEX1 ABCA10 MDN1 NAV1 DNAH8 ABCC10 DNAH3 ABCA6

1.69e-041442018IPR003593
DomainCadherin_CS

DCHS2 CDH26 CDH23 PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

1.78e-041092017IPR020894
DomainDHR-1_domain

DOCK5 DOCK8 DOCK7

1.90e-04112013IPR027007
DomainDHR_2

DOCK5 DOCK8 DOCK7

1.90e-04112013PS51651
DomainDHR_1

DOCK5 DOCK8 DOCK7

1.90e-04112013PS51650
DomainDHR-2

DOCK5 DOCK8 DOCK7

1.90e-04112013PF06920
DomainDOCK

DOCK5 DOCK8 DOCK7

1.90e-04112013IPR026791
DomainDOCK_C

DOCK5 DOCK8 DOCK7

1.90e-04112013IPR010703
DomainDOCK-C2

DOCK5 DOCK8 DOCK7

1.90e-04112013PF14429
DomainDHR-2

DOCK5 DOCK8 DOCK7

1.90e-04112013IPR027357
Domain-

DYSF C2CD2L ESYT2 OTOF PLCD4 SYT2 RAB11FIP1 MYOF

2.04e-0414820182.60.40.150
DomainCADHERIN_1

DCHS2 CDH26 CDH23 PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

2.22e-041132017PS00232
DomainCadherin

DCHS2 CDH26 CDH23 PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

2.22e-041132017PF00028
DomainCADHERIN_2

DCHS2 CDH26 CDH23 PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

2.35e-041142017PS50268
Domain-

DCHS2 CDH26 CDH23 PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

2.35e-0411420172.60.40.60
DomainCadherin-like

DCHS2 CDH26 CDH23 PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

2.61e-041162017IPR015919
DomainFerA

DYSF MYOF

3.43e-0432012SM01200
DomainFerlin_A-domain

DYSF MYOF

3.43e-0432012IPR012560
DomainHDAC4_Gln

HDAC9 HDAC5

3.43e-0432012PF12203
DomainFerA

DYSF MYOF

3.43e-0432012PF08165
DomainHist_deacetylase_Gln_rich_N

HDAC9 HDAC5

3.43e-0432012IPR024643
DomainSerpin_CS

SERPINB9 SERPINB10 SERPINF2 SERPINB2

3.70e-04322014IPR023795
DomainHEAT

UTP20 PPP4R1 SCYL3 PRKDC HTT

3.96e-04582015IPR000357
DomainC2_dom

DYSF C2CD2L ESYT2 OTOF PLCD4 SYT2 RAB11FIP1 MYOF

4.08e-041642018IPR000008
DomainATPase_dyneun-rel_AAA

MDN1 DNAH8 DNAH3

4.10e-04142013IPR011704
DomainAAA_5

MDN1 DNAH8 DNAH3

4.10e-04142013PF07728
DomainC2

DYSF ESYT2 OTOF PLCD4 SYT2 RAB11FIP1 MYOF

5.46e-041312017PF00168
DomainSerpin_dom

SERPINB9 SERPINB10 SERPINF2 SERPINB2

5.86e-04362014IPR023796
DomainCadherin_tail

PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

6.51e-04372014PF15974
DomainCadherin_CBD

PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

6.51e-04372014IPR031904
DomainSERPIN

SERPINB9 SERPINB10 SERPINF2 SERPINB2

6.51e-04372014PS00284
DomainSERPIN

SERPINB9 SERPINB10 SERPINF2 SERPINB2

6.51e-04372014SM00093
DomainDysFC

DYSF MYOF

6.82e-0442012SM00694
DomainDysFN

DYSF MYOF

6.82e-0442012SM00693
DomainHistone_deAcase_II_euk

HDAC9 HDAC5

6.82e-0442012IPR017320
DomainPeroxin/Ferlin

DYSF MYOF

6.82e-0442012IPR006614
DomainKCL_cotranspt

SLC12A5 SLC12A6

6.82e-0442012IPR000076
DomainC2

DYSF ESYT2 OTOF PLCD4 SYT2 RAB11FIP1 MYOF

7.13e-041372017SM00239
DomainSerpin

SERPINB9 SERPINB10 SERPINF2 SERPINB2

7.22e-04382014PF00079
DomainSerpin_fam

SERPINB9 SERPINB10 SERPINF2 SERPINB2

7.97e-04392014IPR000215
DomainLaminin_G_2

CNTNAP3B CNTNAP3 NELL2 LAMA4

8.79e-04402014PF02210
DomainC2

DYSF ESYT2 OTOF PLCD4 SYT2 RAB11FIP1 MYOF

8.80e-041422017PS50004
DomainHEAT_REPEAT

UTP20 PPP4R1 SCYL3 PRKDC HTT

9.43e-04702015PS50077
DomainARM-type_fold

DOCK5 NOC4L UTP20 PPP4R1 DOCK8 SCYL3 HUWE1 ARFGEF3 PRKDC NUP188 HTT

1.15e-0333920111IPR016024
DomainLamG

CNTNAP3B CNTNAP3 NELL2 LAMA4

1.26e-03442014SM00282
DomainDUF3398

DOCK8 DOCK7

1.68e-0362012PF11878
DomainDOCK_C/D_N

DOCK8 DOCK7

1.68e-0362012IPR021816
DomainPentatricopeptide_repeat

DENND4B PRKDC HTT

1.86e-03232013IPR002885
DomainSLC12A_fam

SLC12A5 SLC12A6

2.34e-0372012IPR004842
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TMEM94 DGKQ DYSF AHDC1 BAP1 ITPR3 C2CD2L KMT2C TNRC18 MDN1 EIF4ENIF1 NAV1 NLRC5 ABCC10 ENGASE FRAS1 SH3RF1 L1CAM KSR2 LAMB3 HUWE1 TFE3 KCNH3 MYOF ZNF500 ZFYVE26 PRKDC NUP188 HTT

3.04e-1111052092935748872
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

RTEL1 ADGRV1 BAP1 C2CD2L CEP68 KMT2C ESYT2 SULF2 DOP1B HDAC5 MYOF MACF1 AKAP11 GRIP2

1.10e-102252091412168954
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DGKA DOCK5 KMT2C FREM2 MDN1 DENND4B UTP20 OR7A10 HSPA8 GP1BA DOP1B DNAH3 BRME1 LAMB3 PCDHA5 HUWE1 RNF123 GTF3C1 TBK1 PRKDC NUP188

4.59e-097362092129676528
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

URB2 AHDC1 TNRC18 SACS AP5Z1 SHOC1 NAV1 AHCTF1 HUWE1 MYOF MACF1 PRKDC SLC4A5

1.29e-073322091337433992
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AVL9 TMEM94 URB2 SLC12A5 C2CD2L DENND4B NAV1 DOP1B FNIP2 FRAS1 HDAC5 ARFGEF3 DOCK7 MACF1

2.05e-074072091412693553
Pubmed

The C2 domains of otoferlin, dysferlin, and myoferlin alter the packing of lipid bilayers.

DYSF OTOF MYOF

2.14e-073209323859474
Pubmed

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

TPSAB1 TPSD1 TPSB2

2.14e-07320939920877
Pubmed

FerA is a Membrane-Associating Four-Helix Bundle Domain in the Ferlin Family of Membrane-Fusion Proteins.

DYSF OTOF MYOF

2.14e-073209330026467
Pubmed

Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.

TPSAB1 TPSD1 TPSB2

2.14e-073209319748655
Pubmed

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

FREM2 FRAS1 FREM3

2.14e-073209321993971
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ESYT2 SULF2 NAV1 KCNH3 ARFGEF3 MYOF MACF1 GRIP2

2.17e-07103209810574462
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

HDAC9 RTEL1 SEMA4C CEP68 NEK1 TNRC18 SACS ADAMTS16 GRIN3A EXOC7 RNF169 SH3RF1 EPB41L5 MYOF MACF1

3.57e-074932091515368895
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

RTEL1 CDH23 ADGRV1 HSPA8 FRAS1 MACF1 NUP188 CAPRIN1 HTT

3.84e-07152209934299191
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

PEX1 RABL3 SEMA4C ITPR3 ESYT2 DOP1B FNIP2 SLC12A6 VEZT SCYL3 KIF16B ARFGEF3 NBAS LRCH4 AKAP11

4.72e-075042091534432599
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PEX1 DGKA DOCK5 FREM2 TMEM62 SULF2 ANAPC2 EXOC7 SF3B2 PPP4R1 FRAS1 LAMB3 GTF3C1 TBK1 DOCK7 LRCH4 PCDHGC3

4.86e-076502091738777146
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

URB2 ITPR3 PNPT1 MDN1 NOC4L UTP20 HSPA2 SF3B2 AHCTF1 HUWE1 TGM3 GTF3C1 DOCK7 MACF1 PRKDC NUP188 CAPRIN1

5.18e-076532091722586326
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

PPP1R13L ADD3 NEK1 ESYT2 EIF4ENIF1 ARFGEF3 DOCK7 MACF1 AKAP11 CAPRIN1

6.18e-072092091036779422
Pubmed

Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.

FREM2 FRAS1 FREM3

8.52e-074209318563433
Pubmed

Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.

FREM2 FRAS1 FREM3

8.52e-074209324101214
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPHB6 HDAC9 DCHS2 ADD3 NELL2 OTOF SACS UBE3A SULF1 SCG2 HPS4 EXOC7 HSPA2 MNAT1 SF3B2 DOP1B PPP4R1 HUWE1 RNF123 SBNO1 MTM1 MACF1 PRKDC CAPRIN1

9.75e-0712852092435914814
Pubmed

Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.

FREM2 FRAS1 FREM3

2.12e-065209317251066
Pubmed

Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.

FREM2 FRAS1 FREM3

2.12e-065209317596926
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FREM2 FRAS1 FREM3 GRIP2

3.63e-0618209414730302
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PEX1 RABL3 LACTB ITPR3 C2CD2L PNPT1 ESYT2 MDN1 ADSL EIF4ENIF1 ANGEL2 NAV1 NOC4L MTO1 VEZT AHCTF1 KIF16B ADCK2 HUWE1 ARFGEF3 GLMN NBAS AKAP11 NUP188 CAPRIN1

4.12e-0614962092532877691
Pubmed

New developments in the genetics and activation of mast cell proteases.

TPSAB1 TPSD1 TPSB2

4.22e-066209312217407
Pubmed

Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.

FREM2 FRAS1 FREM3

4.22e-066209317462874
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PEX1 URB2 RABL3 SEMA4C ITPR3 ESYT2 UBE3A ANAPC2 UTP20 EXOC7 HSPA2 VEZT AHCTF1 HUWE1 ARFGEF3 GLMN TBK1 PRKDC NUP188

4.76e-069422091931073040
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FREM2 HMCN2 SERPINF2 FRAS1 LAMA4 LAMB3 ITIH5 TGM3

8.31e-06167209822159717
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

BAP1 NEK1 EIF4ENIF1 NAV1 SLC39A7 KNL1 SFMBT1 HDAC5 HUWE1 GTF3C1 TBK1 DOCK7

9.74e-064182091234709266
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TMEM94 PPP1R13L AFAP1L1 C2CD2L EIF4ENIF1 NAV1 EXOC7 SF3B2 KNL1 RNF169 VEZT EPB41L5 HUWE1 GLMN NBAS LRCH4

1.05e-057332091634672954
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CDH26 RTEL1 ANKMY1 ADGRV1 ARHGEF16 AHDC1 DOCK5 KMT2C ESYT2 TNRC18 NAV1 NLRC5 SLC12A6 VEZT PCDHGB1 KSR2 SYT2 HUWE1 ARFGEF3 GTF3C1 TBK1 MACF1 SLC4A5 HTT

1.18e-0514892092428611215
Pubmed

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DYSF GPAT2 ABCC10 DOCK8 RAB11FIP1 LRCH4

1.29e-0585209615449545
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

EIF4ENIF1 NAV1 CRTC3 SH3RF1 HDAC5 DOCK8 RAB11FIP1 GLMN TBK1 DOCK7 LRCH4 PRKDC

1.85e-054462091224255178
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

2.32e-0528209415347688
Pubmed

The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.

FREM2 FRAS1 FREM3

2.49e-0510209315345741
Pubmed

A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.

CDH23 ADGRV1 OTOF

2.49e-0510209317329413
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

PEX1 RABL3 SEMA4C ITPR3 C2CD2L BTN3A3 ESYT2 DENND4B VEZT SCYL3 KIF16B NBAS

2.96e-054682091231056421
Pubmed

Isolation and characterization of proteins associated with histone H3 tails in vivo.

HDAC9 KMT2C SF3B2 HDAC5

3.07e-0530209417403666
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

ITPR3 DOCK5 UTP20 NBAS MYOF DOCK7 PRKDC CAPRIN1

3.28e-05202209833005030
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SPART RABL3 LACTB ADD3 ITPR3 PNPT1 ESYT2 MDN1 SACS NOC4L HSPA2 SF3B2 HSPA8 FRAS1 VEZT AHCTF1 KIF16B EPB41L5 RAB11FIP1 NBAS MACF1 AKAP11 CAPRIN1

3.46e-0514872092333957083
Pubmed

Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.

DYSF MYOF

3.59e-052209211959863
Pubmed

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity.

SULF2 SULF1

3.59e-052209216901266
Pubmed

Loss of dysferlin or myoferlin results in differential defects in excitation-contraction coupling in mouse skeletal muscle.

DYSF MYOF

3.59e-052209234354129
Pubmed

Ferlin Overview: From Membrane to Cancer Biology.

OTOF MYOF

3.59e-052209231443490
Pubmed

The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.

TPSAB1 TPSB2

3.59e-052209210500112
Pubmed

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis.

TPSAB1 TPSD1

3.59e-052209218668540
Pubmed

Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis.

FREM2 FRAS1

3.59e-052209221900877
Pubmed

HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.

SULF2 SULF1

3.59e-052209216192265
Pubmed

Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality.

SULF2 SULF1

3.59e-052209228657777
Pubmed

Phosphorylation of activation function-1 regulates proteasome-dependent nuclear mobility and E6-associated protein ubiquitin ligase recruitment to the estrogen receptor beta.

ESR2 UBE3A

3.59e-052209217962381
Pubmed

SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression.

SULF2 SULF1

3.59e-052209224726914
Pubmed

Apigenin manipulates the ubiquitin-proteasome system to rescue estrogen receptor-β from degradation and induce apoptosis in prostate cancer cells.

ESR2 UBE3A

3.59e-052209225408199
Pubmed

Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity.

SULF2 SULF1

3.59e-052209220394677
Pubmed

Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.

TPSAB1 TPSB2

3.59e-052209210898108
Pubmed

SULFs in human neoplasia: implication as progression and prognosis factors.

SULF2 SULF1

3.59e-052209221599997
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3B CNTNAP3

3.59e-052209226807827
Pubmed

Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood.

TPSAB1 TPSD1

3.59e-05220929064323
Pubmed

Impaired mitochondrial dynamics underlie axonal defects in hereditary spastic paraplegias.

AP5Z1 ZFYVE26

3.59e-052209229726929
Pubmed

Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.

SULF2 SULF1

3.59e-052209227294358
Pubmed

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.

TPSAB1 TPSB2

3.59e-05220929521329
Pubmed

Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.

SULF2 SULF1

3.59e-052209220479257
Pubmed

Molecular study of 33 families with Fraser syndrome new data and mutation review.

FREM2 FRAS1

3.59e-052209218671281
Pubmed

Delta tryptase is expressed in multiple human tissues, and a recombinant form has proteolytic activity.

TPSAB1 TPSD1

3.59e-052209212391231
Pubmed

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.

SULF2 SULF1

3.59e-052209226448642
Pubmed

Novel loss of function variants in FRAS1 AND FREM2 underlie renal agenesis in consanguineous families.

FREM2 FRAS1

3.59e-052209232643034
Pubmed

Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain.

SULF2 SULF1

3.59e-052209235131262
Pubmed

Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.

TPSAB1 TPSB2

3.59e-052209210391906
Pubmed

Genetic deficiency of human mast cell alpha-tryptase.

TPSAB1 TPSD1

3.59e-052209212100045
Pubmed

Loss-of-function mutations in MYO15A and OTOF cause non-syndromic hearing loss in two Yemeni families.

OTOF MYO15A

3.59e-052209237189200
Pubmed

Identification and molecular cloning of a novel mouse mucosal mast cell serine protease.

TPSAB1 TPSD1

3.59e-05220921688433
Pubmed

Expression of Heparan Sulfate Endosulfatases in the Adult Mouse Brain: Co-expression of Sulf1 and Dopamine D1/D2 Receptors.

SULF2 SULF1

3.59e-052209234489650
Pubmed

Lack of expression of the tryptase mouse mast cell protease 7 in mast cells of the C57BL/6J mouse.

TPSAB1 TPSD1

3.59e-05220928077672
Pubmed

N-myc downstream-regulated gene 2 promotes the protein stability of estrogen receptor beta via inhibition of ubiquitin-protein ligase E3A to suppress colorectal cancer.

ESR2 UBE3A

3.59e-052209233456993
Pubmed

Transcriptional regulation of mouse mast cell protease-7 by TGF-beta.

TPSAB1 TPSD1

3.59e-052209216730810
Pubmed

Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration.

SULF2 SULF1

3.59e-052209217920055
Pubmed

NLRC5 exerts anti-endometriosis effects through inhibiting ERβ-mediated inflammatory response.

ESR2 NLRC5

3.59e-052209239218863
Pubmed

Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.

SULF2 SULF1

3.59e-052209212368295
Pubmed

A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9.

CDH23 OTOF

3.59e-052209217967520
Pubmed

Overexpression of Sulf2 in idiopathic pulmonary fibrosis.

SULF2 SULF1

3.59e-052209223418199
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3B CNTNAP3

3.59e-052209231150793
Pubmed

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation.

BAP1 ITPR3

3.59e-052209228614305
Pubmed

Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy.

DYSF PRKDC

3.59e-052209221364666
Pubmed

Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches.

SULF2 SULF1

3.59e-052209234324645
Pubmed

Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling.

SULF2 SULF1

3.59e-052209218687675
Pubmed

Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.

SULF2 SULF1

3.59e-052209231461325
Pubmed

Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.

TPSAB1 TPSB2

3.59e-05220928434231
Pubmed

Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin.

DYSF MYOF

3.59e-052209231004665
Pubmed

Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.

GRIN3A HTT

3.59e-052209223852340
Pubmed

Functional consequences of the subdomain organization of the sulfs.

SULF2 SULF1

3.59e-052209219520866
Pubmed

In silico discovery and experimental validation of new protein-protein interactions.

DYSF HTT

3.59e-052209221280221
Pubmed

The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.

SULF2 SULF1

3.59e-052209223950901
Pubmed

Increase in TPSB2 and TPSD1 Expression in Synovium of Hip Osteoarthritis Patients Who Are Overweight.

TPSD1 TPSB2

3.59e-052209237511292
Pubmed

Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation.

TPSAB1 TPSD1

3.59e-052209218854315
Pubmed

Cloning and characterization of a second complementary DNA for human tryptase.

TPSAB1 TPSB2

3.59e-05220922203827
Pubmed

Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.

SULF2 SULF1

3.59e-052209223480519
Pubmed

Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage.

SULF2 SULF1

3.59e-052209218507859
Pubmed

Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling.

SULF2 SULF1

3.59e-052209226764203
Pubmed

SULF1/SULF2 reactivation during liver damage and tumour growth.

SULF2 SULF1

3.59e-052209227013228
Pubmed

While dysferlin and myoferlin are coexpressed in the human placenta, only dysferlin expression is responsive to trophoblast fusion in model systems.

DYSF MYOF

3.59e-052209219228595
Pubmed

Essential role for mast cell tryptase in acute experimental colitis.

TPSAB1 TPSD1

3.59e-052209221173247
InteractionPFN1 interactions

ESR2 BAP1 SEMA4C NEK1 ESYT2 NAV1 SF3B2 HSPA8 DOP1B HDAC5 DOCK8 TFE3 NBAS RNF123 DOCK7 MACF1 HTT MTSS2

3.24e-0650919918int:PFN1
InteractionEEF1AKMT3 interactions

RTEL1 PEX1 DGKA DOCK5 MDN1 UBE3A NAV1 GPAT2 HSPA2 HSPA8 HUWE1 RNF123 GTF3C1 TBK1 DOCK7

3.57e-0636419915int:EEF1AKMT3
InteractionPCDHGB2 interactions

PPP1R13L C2CD2L VEZT PCDHGB1 PCDHGA9 PCDHGC3

4.44e-06441996int:PCDHGB2
InteractionD2HGDH interactions

RTEL1 PEX1 PPP1R13L GPAT2 MNAT1 HSPA8 RNF123 TBK1 DOCK7

1.50e-051461999int:D2HGDH
InteractionCDH26 interactions

CDH26 MNAT1 HTT

1.86e-0561993int:CDH26
InteractionTOP3B interactions

RTEL1 TMEM94 DGKQ DYSF AHDC1 BAP1 ITPR3 C2CD2L KMT2C TNRC18 MDN1 EIF4ENIF1 NAV1 NLRC5 ABCC10 ENGASE FRAS1 SH3RF1 RRM2B L1CAM KSR2 LAMB3 HUWE1 TFE3 KCNH3 MYOF ZNF500 ZFYVE26 PRKDC NUP188 CAPRIN1 HTT

1.94e-05147019932int:TOP3B
InteractionNPTN interactions

MDN1 AP5Z1 ANAPC2 NOC4L UTP20 EXOC7 DOP1B SYT2 HUWE1 ARFGEF3 ZFYVE26 HTT

2.19e-0527819912int:NPTN
InteractionSULF2 interactions

ESR2 CDH23 TNRC18 SULF2 SULF1 EPB41L5 AKAP11 IL5RA

2.41e-051191998int:SULF2
InteractionMEX3A interactions

URB2 AHDC1 TNRC18 EIF4ENIF1 SACS AP5Z1 SHOC1 NAV1 AHCTF1 HUWE1 MYOF MACF1 PRKDC SLC4A5

2.98e-0538419914int:MEX3A
InteractionBAG2 interactions

PEX1 PPP1R13L BAP1 DOCK5 EIF4ENIF1 AP5Z1 MTO1 HSPA2 HSPA8 KNL1 SLC12A6 HDAC5 RRM2B KIF16B LAMB3 HUWE1 DOCK7 HTT

4.77e-0562219918int:BAG2
InteractionGPR182 interactions

URB2 DOCK5 ESYT2 MDN1 AP5Z1 NAV1 UTP20 EXOC7 GPAT2 DOP1B AHCTF1 ADCK2 ARFGEF3 PRKDC HTT

4.91e-0545519915int:GPR182
InteractionPCDHGB3 interactions

PCDHGB1 RNF123 PCDHGC3

5.12e-0581993int:PCDHGB3
InteractionLTA4H interactions

BAP1 TMEM62 ADSL HSPA8 HDAC5 RNF123

6.14e-05691996int:LTA4H
InteractionFBXO2 interactions

CNTNAP3B CNTNAP3 ADGRV1 SEMA4C NELL2 SULF2 SULF1 ANAPC2 FRAS1 VASN L1CAM LAMA4 LAMB3 HTT

6.21e-0541119914int:FBXO2
InteractionRNF123 interactions

DGKA DOCK5 KMT2C FREM2 MDN1 DENND4B UTP20 OR7A10 HSPA8 GP1BA DOP1B DNAH3 BRME1 LAMB3 PCDHA5 HUWE1 RNF123 GTF3C1 TBK1 PRKDC NUP188

6.97e-0582419921int:RNF123
InteractionCDRT15P3 interactions

RTEL1 PEX1 HSPA2 HSPA8

8.40e-05241994int:CDRT15P3
GeneFamilyFerlin family

DYSF OTOF MYOF

8.74e-0661393828
GeneFamilyOlfactory receptors, family 12

OR12D2 OR12D1

1.75e-0431392160
GeneFamilySerpin peptidase inhibitors

SERPINB9 SERPINB10 SERPINF2 SERPINB2

1.81e-04371394739
GeneFamilyHistone deacetylases, class IIA

HDAC9 HDAC5

3.49e-0441392992
GeneFamilyClustered protocadherins

PCDHGB1 PCDHGA9 PCDHA5 PCDHGC3

1.49e-0364139420
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKA DGKQ

2.54e-031013921178
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ITPR3 SACS KNL1 ARFGEF3 PPP1R18 AKAP11

2.77e-031811396694
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

CNTNAP3 DGKA SIRPG BTN3A3 NLRC5 THEMIS PLCD4 ADCK2 MACF1 AKAP11 LTB

2.71e-0919820911ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HDAC9 ASIC2 FHAD1 SERPINB10 ATP13A4 DNAH3 RRM2B FICD ZNF500

1.82e-0813720998e2fa2ef8becace96a68bb85c002329110902fbb
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

AVL9 DENND4B DOP1B DOCK8 AHCTF1 HUWE1 NBAS MTM1 MACF1 PRKDC

1.88e-0818520910a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

ADGRV1 DOCK5 FREM2 PPP4R1 ATP13A4 SH3RF1 EPB41L5 RAB11FIP1 ARFGEF3 LRRC36

2.19e-0818820910707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HDAC9 OXCT2 SULF2 SERPINB9 CLCN1 SERPINF2 SLC30A10 UTF1 KIF16B LTB

3.75e-081992091026ea06960e8ea061a71756750b84489609f78162
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Cbln1-Trps1_(Medial_entorrhinal_cortex,_Cbln1+/Trps1+)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ESR2 CDH23 THEMIS ITPRID1 FREM3 SERPINB2

1.41e-075120969656b37262f228753203ca49aab93e86066b69a5
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Cbln1-Trps1_(Medial_entorrhinal_cortex,_Cbln1+/Trps1+)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ESR2 CDH23 THEMIS ITPRID1 FREM3 SERPINB2

1.41e-0751209610cfed29c2fa495d4527e1e4d8edf21edaf1d0fa
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-DC1|lymph-node_spleen / Manually curated celltypes from each tissue

HDAC9 ASIC2 DYSF SULF2 CLCN1 NAV1 SERPINF2 FNIP2 TYMP

2.19e-071832099c9e3d91f4c3395a73295b92e25608e0effb5d241
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

AVL9 DOP1B DOCK8 AHCTF1 HUWE1 NBAS MTM1 MACF1 PRKDC

2.52e-0718620998571956890fc9894d766ba294a28e376b4aba428
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

DGKA ADD3 SIRPG PNPT1 MDN1 GIMAP6 HSPA8 THEMIS LTB

4.63e-072002099d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCellControl|World / group, cell type (main and fine annotations)

ADGRV1 FREM2 ATP13A4 SH3RF1 EPB41L5 RAB11FIP1 ARFGEF3 LRRC36

1.33e-061682098a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellwk_08-11-Epithelial-PNS-FGFBP2+_Neural_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HDAC9 NELL2 SCG2 NLRC5 L1CAM PLCD4 TPSD1 GRIP2

1.97e-06177209815a5c96ea840376e54933ebe7a8334a11d9ce411
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF16 SERPINB9 ATP13A4 EPB41L5 LAMB3 RAB11FIP1 PRKAG3 SLC4A5

2.06e-061782098a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF16 SERPINB9 ATP13A4 EPB41L5 LAMB3 RAB11FIP1 PRKAG3 SLC4A5

2.06e-061782098b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Slc17a7-Slc17a6.Calb1-Rorb-Il1rapl2_(Layer_5b)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESR2 ANKMY1 FRAS1 LAMB3 TGM3 MYO15A

2.11e-06802096402aba070f0728ebda9db7a8fa85441533755ff4
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HDAC9 SULF2 SERPINB9 CLCN1 NAV1 SERPINF2 KIF16B RAB11FIP1

2.63e-061842098667846c422cfa27e949a24844a305df859cb6760
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HDAC9 SULF2 SERPINB9 CLCN1 NAV1 SERPINF2 KIF16B RAB11FIP1

2.63e-061842098a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CDH23 MDN1 GPAT2 KNL1 ATP13A4 SH3RF1 UBE2C KLHL31

2.85e-0618620985cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellnormal_Lung-Myeloid_cells-CD141+_DCs|normal_Lung / Location, Cell class and cell subclass

HDAC9 SULF2 SERPINB9 CLCN1 NAV1 SERPINF2 KIF16B RAB11FIP1

2.85e-061862098a6698a2f4edd81b67e06531ede0e207dd0309205
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 ASIC2 ITPR3 ESYT2 PPP4R1 LAMA4 LAMB3 MYOF

2.97e-06187209842a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 ASIC2 ITPR3 ESYT2 PPP4R1 LAMA4 LAMB3 MYOF

2.97e-06187209864afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HDAC9 ASIC2 ITPR3 ESYT2 PPP4R1 LAMA4 LAMB3 MYOF

2.97e-06187209887b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellCOVID-19-Myeloid-DC1|COVID-19 / Condition, Lineage and Cell class

HDAC9 SULF2 SERPINB9 CLCN1 NAV1 SERPINF2 KIF16B ABCA6

3.47e-0619120989e44357cdeca46d2b26124bb063c8422ef930083
ToppCellCOPD-Myeloid-cDC1|COPD / Disease state, Lineage and Cell class

HDAC9 SULF2 SERPINB9 SERPINF2 FNIP2 KIF16B RAB11FIP1 MTSS2

3.61e-061922098bd3d00b094d92463b06023361a71240851a542b8
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADGRV1 ITPR3 FREM2 ATP13A4 SH3RF1 EPB41L5 RAB11FIP1 ARFGEF3

3.75e-061932098a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 SIRPG GIMAP6 HSPA8 THEMIS PPP1R18 LTB TPSB2

3.89e-0619420989116451614431e3cf9bd7d4d626bf4bd23420e36
ToppCellBAL-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

HDAC9 DYSF SERPINB9 CLCN1 SERPINF2 KIF16B RAB11FIP1 LTB

4.04e-0619520982d31a1c2878c86a49a278b6c7decafabf26c3a5c
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DGKA KMT2E ADD3 SIRPG NELL2 THEMIS MACF1 LTB

4.04e-0619520984bdedd924564a260841a9153604026b57487c83d
ToppCell3'_v3-Lung-Myeloid_Monocytic-Classical_monocytes|Lung / Manually curated celltypes from each tissue

PLBD1 PADI4 ADGRE2 DYSF SULF2 SERPINB9 TYMP SERPINB2

4.70e-061992098bfd0d171ea6bb7abd5cdfeac22608cc190aaa2be
ToppCellTransverse-Dendritic_cell-cDC1|Transverse / Region, Cell class and subclass

PLBD1 DYSF SULF2 CLCN1 NAV1 SERPINF2 FNIP2 KIF16B

4.70e-061992098b68419939d206417158a703f60a374bf8ec5d5a1
ToppCellTransverse-(5)_Dendritic_cell-(51)_cDC1|Transverse / shred on region, Cell_type, and subtype

PLBD1 DYSF SULF2 CLCN1 NAV1 SERPINF2 FNIP2 KIF16B

4.70e-06199209852dd1c4cd372f8ee515307a9200e357bb2145888
ToppCellSigmoid-(5)_Dendritic_cell-(51)_cDC1|Sigmoid / shred on region, Cell_type, and subtype

PLBD1 DYSF SULF2 NAV1 SERPINF2 FNIP2 ISYNA1 SH3RF1

4.87e-0620020984ce0a2238c90622e41fd86ac4b7d82adf4af2c3b
ToppCellSigmoid-Dendritic_cell-cDC1|Sigmoid / Region, Cell class and subclass

PLBD1 DYSF SULF2 NAV1 SERPINF2 FNIP2 ISYNA1 SH3RF1

4.87e-0620020983523ec986e8c9e176e08836c974b1de8b56d8b16
ToppCell(51)_cDC1|World / shred on Cell_type and subtype

PLBD1 DYSF SULF2 CLCN1 NAV1 SERPINF2 FNIP2 KIF16B

5.64e-062042098a8cf4180c406674b7541917d1fc6127686ba5f8a
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLBD1 DOCK5 SERPINB10 DENND4B DOCK8 L1CAM TGM3

9.94e-061582097121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLBD1 DOCK5 SERPINB10 DENND4B DOCK8 L1CAM TGM3

1.08e-051602097bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

EPHB6 DGKA ADGRV1 KMT2E AHDC1 TNRC18 KSR2

1.22e-0516320974104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCellfacs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLBD1 CDH23 DOCK5 SERPINB10 DOCK8 L1CAM TGM3

1.27e-05164209711dfd84f5fb90de330858e1e852848832734e004
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 ADGRE2 NAV1 TPSD1 ADAMTS14 IL5RA TPSB2

1.27e-0516420972c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 EPB41L5 LAMB3 RAB11FIP1 PRKAG3 ARFGEF3 PRKDC

1.37e-05166209711b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 EPB41L5 LAMB3 RAB11FIP1 PRKAG3 ARFGEF3 PRKDC

1.37e-051662097fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPSAB1 PADI4 ADGRE2 DOCK8 TPSD1 IL5RA TPSB2

1.79e-051732097b9dc42d629d13e63aada5ae49ba0cbb0952c5fe9
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PADI4 SULF2 SERPINB9 NAV1 SERPINF2 UTF1 LTB

1.86e-051742097c8cec89369cf3896c5626e447051e76a142cb6df
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R13L FHAD1 RUNDC3A LAMB3 IFTAP SLC4A5 LRRC36

1.86e-05174209746838b4bb9b4d8ce5e1c608a700e7f393bc52658
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R13L FHAD1 RUNDC3A LAMB3 IFTAP SLC4A5 LRRC36

1.86e-051742097103594eeb600eb5bc9cbf09a65b286b3a3a18cdc
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PADI4 SULF2 SERPINB9 NAV1 SERPINF2 UTF1 LTB

1.86e-051742097991f7eab69ea3ee1045a4e44ce60a96db13df6d1
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ESR2 CDH23 THEMIS ITPRID1 SERPINB2

1.95e-057020958d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNTNAP3B ADD3 AFAP1L1 DOCK5 CEP68 LAMA4 MACF1

2.15e-051782097ad3de3e03a401dac64431a541899445262246347
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ESR2 ADGRV1 FNIP2 ATP13A4 SH3RF1 EPB41L5 ARFGEF3

2.15e-051782097f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADGRE2 DYSF AFAP1L1 ADAMTS16 DOCK8 PCDHGA9 LAMA4

2.23e-051792097cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DGKA SIRPG NELL2 GIMAP6 HSPA8 THEMIS LTB

2.31e-051802097f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPSAB1 PADI4 DOCK8 TPSD1 SERPINB2 IL5RA TPSB2

2.31e-0518020971c5515f29ead129bee3b4ca27799796956811a39
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-cDC1|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERPINB9 CLCN1 NAV1 SERPINF2 FNIP2 KIF16B TYMP

2.39e-05181209784ca8c9c036478a6d3a2071919d09065455d417c
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A4 FRAS1 EPB41L5 LAMB3 RAB11FIP1 TRIM3 PRKAG3

2.48e-051822097573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A4 FRAS1 EPB41L5 LAMB3 RAB11FIP1 TRIM3 PRKAG3

2.48e-0518220976cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell367C-Myeloid-Dendritic-cDC1|367C / Donor, Lineage, Cell class and subclass (all cells)

HDAC9 PADI4 SERPINB9 SERPINF2 KIF16B RAB11FIP1 LTB

2.48e-0518220976f5228ac47f9ab46d165740cf2655b5ba217acbe
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 DYSF AFAP1L1 DOCK5 CEP68 SULF2 SERPINB9

2.57e-051832097764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

ADGRV1 FREM2 ATP13A4 SH3RF1 ARFGEF3 CSF3 LRRC36

2.57e-0518320978e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

HDAC9 SULF2 SERPINB9 SERPINF2 FNIP2 ABCA6 LTB

2.57e-051832097e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 FREM2 ADAMTS16 ATP13A4 FRAS1 ARFGEF3 MYO15A

2.66e-0518420972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HDAC9 NAV1 SERPINF2 UTF1 RAB11FIP1 ABCA6 LTB

2.66e-0518420971c56378b3888c46258d446b47de4d6282fe74b0d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 FREM2 ADAMTS16 ATP13A4 FRAS1 ARFGEF3 MYO15A

2.66e-0518420972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 FREM2 ADAMTS16 ATP13A4 FRAS1 ARFGEF3 MYO15A

2.66e-051842097ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HDAC9 NAV1 SERPINF2 UTF1 RAB11FIP1 ABCA6 LTB

2.66e-051842097a45980306c4e697a2703bed72a7b48fb23d942f4
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B CNTNAP3 DYSF AFAP1L1 SULF2 GIMAP6 DOCK8

2.75e-0518520973be9e05b929ac4d956b1d53284072f668a6c1959
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B CNTNAP3 DYSF AFAP1L1 SULF2 GIMAP6 DOCK8

2.75e-051852097c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B CNTNAP3 DYSF AFAP1L1 GIMAP6 DOCK8 LTB

2.85e-0518620975d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R13L ATP13A4 FRAS1 EPB41L5 LAMB3 RAB11FIP1 MYOF

2.85e-0518620973aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|bone_marrow / Manually curated celltypes from each tissue

PLBD1 PADI4 DYSF KNL1 UBE2C TYMP SERPINB2

2.85e-051862097e82d5e7a976b9cfa2b4640c7a7cd1cfea19c4806
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNTNAP3B ADD3 AFAP1L1 DOCK5 CEP68 LAMA4 MACF1

2.85e-05186209720340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B CNTNAP3 DYSF AFAP1L1 GIMAP6 DOCK8 LTB

2.85e-0518620971da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCell367C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HDAC9 SULF2 SERPINF2 KIF16B RAB11FIP1 PDP1 LTB

2.95e-0518720973748203b62abf51b74dfcfc4f18b3ba831b63a96
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

PADI4 NOC4L UTF1 TYMP SERPINB2 ZFYVE26 CAPRIN1

2.95e-0518720973c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TPSAB1 DGKA ADD3 SIRPG SLC1A6 TPSD1 LTB

3.05e-05188209788b808561ebde997ac8a8bbd1d9bbda49bbb6646
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK5 ATP13A4 SH3RF1 EPB41L5 LAMB3 RAB11FIP1 MYOF

3.05e-051882097eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

HDAC9 SULF2 SERPINB9 NLRC5 SERPINF2 KIF16B LTB

3.05e-05188209747bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 DYSF AFAP1L1 DOCK5 SULF2 LAMA4

3.05e-051882097c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellIPF-Myeloid-cDC1|IPF / Disease state, Lineage and Cell class

HDAC9 SULF2 SERPINB9 NLRC5 SERPINF2 KIF16B LTB

3.05e-0518820972331a2bae1383820d598e93aa86c75b101069bac
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 DYSF AFAP1L1 DOCK5 SULF2 LAMA4

3.05e-0518820972db80767903703e7e0a1a37c598f7877a909ee94
ToppCell10x5'v1-week_12-13-Lymphocytic_T-T_NK-CD4_T_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DGKA ADD3 SIRPG NELL2 GIMAP6 THEMIS LTB

3.16e-0518920970f0a1212e525a7385a27d625524fa7beffa90f44
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 FREM2 ATP13A4 FRAS1 KSR2 LAMB3 ARFGEF3

3.16e-0518920977659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B CNTNAP3 DYSF AFAP1L1 HMCN2 NAV1 ITIH5

3.16e-0518920976463890d8dbee4bc198f91628a5f784970de786a
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 ARHGEF16 FREM2 LAMB3 ITPRID1 ARFGEF3 LRRC36

3.16e-051892097c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDH23 ABCA10 HMCN2 SULF1 GRIN3A LAMA4 ABCA6

3.27e-051902097efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DGKA SIRPG NELL2 NLRC5 THEMIS DOCK8 LTB

3.27e-0519020975b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCellCOPD-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

PADI4 ADGRE2 ADD3 DOCK5 SULF2 SERPINB9 AHCTF1

3.27e-051902097aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

PADI4 ADGRE2 ADD3 DOCK5 SULF2 SERPINB9 AHCTF1

3.27e-051902097ed978cd5d9da87b49878a330e362762c487f849f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DGKA SIRPG NELL2 NLRC5 THEMIS DOCK8 LTB

3.27e-05190209707ea0578ca0561077557203ae660530f53fc4067
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DGKA SIRPG NELL2 NLRC5 THEMIS DOCK8 LTB

3.38e-05191209796a7179a845d3daa046ed71fa45c51255f130a7f
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 FREM2 ATP13A4 SH3RF1 EPB41L5 ARFGEF3 LRRC36

3.38e-051912097e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

HDAC9 SULF2 SERPINB9 NLRC5 KIF16B LTB MTSS2

3.38e-0519120973480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

PNPT1 DOP1B AHCTF1 HUWE1 NBAS MACF1 PRKDC

3.38e-0519120979454f642c3621370fa23640b631301346b300950
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB6 PLBD1 PPP1R13L ITPR3 SERPINB10 LAMB3 SERPINB2

3.38e-051912097ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellP07-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SERPINB9 FRAS1 EPB41L5 LAMB3 RAB11FIP1 TRIM3 SLC4A5

3.38e-0519120970f360766490bef3495c42f6421b22a988cfc68fb
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 PADI4 ADGRE2 DYSF TPSD1 TPSB2 ZNF445

3.49e-0519220973ce486cd5171f2d04ac4f7f87bead8b0d8c99c17
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 ITPR3 FREM2 TMEM62 KSR2 LAMB3 LRRC36

3.49e-051922097d3634574b2e8d2ded6446969361b70761b331aea
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DGKA ESYT2 NELL2 NLRC5 GIMAP6 HSPA8 THEMIS

3.49e-0519220971c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DGKA ADD3 SIRPG NELL2 HSPA8 THEMIS LTB

3.49e-05192209735557254738844c27ffcd00f3287fbcc0a4d0f3b
ToppCell367C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HDAC9 SULF2 SERPINB9 SERPINF2 UTF1 RAB11FIP1 LTB

3.49e-051922097877aaf61d8fc40e7013944a0180306dd0bb0557f
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 FREM2 ATP13A4 FRAS1 KSR2 LAMB3 ARFGEF3

3.49e-051922097b99f8236ef4ccdc75c02abea381cae6453205f6f
Drug1c5s

TPSAB1 TPSD1 SERPINB2 TPSB2

1.31e-06102064CID000444753
DrugBrunfelsamidine

TPSAB1 TPSD1 TPSB2

2.90e-0642063CID005281683
DrugErythromycin [114-07-8]; Up 200; 5.4uM; HL60; HG-U133A

EPHB6 SPART URB2 ARHGEF16 NELL2 TMEM62 AP5Z1 LAMA4 ZNF500 MACF1

1.25e-05196206102010_UP
DrugZardaverine [101975-10-4]; Down 200; 15uM; MCF7; HT_HG-U133A

PPP1R13L DYSF AHDC1 ITPR3 AP5Z1 HPS4 ANAPC2 EXOC7 HSPA2 MYOF

1.25e-05196206104793_DN
DrugIproniazide phosphate [305-33-9]; Down 200; 14.4uM; PC3; HT_HG-U133A

ANKMY1 PPP1R13L SEMA4C EXOC7 HSPA2 SLC12A6 HDAC5 VEZT L1CAM JHY

1.31e-05197206106359_DN
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

DYSF OTOF MYOF

1.17e-0572073DOID:11724 (implicated_via_orthology)
Diseasetryptase beta-2 measurement

TPSAB1 TPSD1 TPSB2

2.77e-0592073EFO_0008306
DiseaseVisceral myopathy familial external ophthalmoplegia

RRM2B TYMP

4.90e-0522072C1848586
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

ASIC2 INHBC DGKQ SULF2 NLRC5 PON3 PRKAG3 ABCA6 DOCK7 MACF1

6.76e-0530720710EFO_0004612, EFO_0020946
DiseaseMITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY SYNDROME

RRM2B TYMP

1.46e-0432072C0872218
DiseaseCryptophthalmos syndrome

FREM2 FRAS1

1.46e-0432072C0265233
DiseaseFRASER SYNDROME 1

FREM2 FRAS1

1.46e-0432072C4551480
DiseaseInherited neuropathies

SPART SACS L1CAM ZFYVE26

1.76e-04402074C0598589
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

INHBC DGKQ SULF2 NLRC5 PRKAG3 ABCA6 DOCK7 MACF1 HTT

2.30e-042912079EFO_0008317, EFO_0020946
DiseaseFraser syndrome (implicated_via_orthology)

FREM2 FRAS1

2.91e-0442072DOID:0090001 (implicated_via_orthology)
Diseasetoll-like receptor 2 measurement

ABCC10 TRIM3

2.91e-0442072EFO_0020777
Diseasecoronary atherosclerosis measurement

HDAC9 NAV1

4.83e-0452072EFO_0007938
Diseasehearing impairment

CDH23 ADGRV1 PNPT1 OTOF MYO15A

6.48e-04982075C1384666
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

LACTB PRKAG3 ABCA6 DOCK7 MACF1 HTT

6.86e-041502076EFO_0004611, EFO_0020947
Diseasecholesterol to total lipids in medium HDL percentage

INHBC NLRC5 PRKAG3 DOCK7

8.44e-04602074EFO_0022237
Diseaserecalcitrant atopic dermatitis

THEMIS NBAS

1.00e-0372072EFO_1000651
Diseasefemoral hernia

PNPT1 SLC30A10

1.00e-0372072EFO_1001791
Diseasecentronuclear myopathy (implicated_via_orthology)

KLHL31 MTM1

1.00e-0372072DOID:14717 (implicated_via_orthology)
Diseaseabdominal aortic artery calcification

HDAC9 NAV1

1.00e-0372072EFO_0004859
Diseaseapolipoprotein A 1 measurement

DGKQ LACTB BTN3A3 TMEM62 SULF2 NLRC5 SLC30A10 HDAC5 ARHGEF25 PRKAG3 ABCA6 SBNO1 DOCK7 MACF1 SMIM44

1.01e-0384820715EFO_0004614
DiseaseIntellectual Disability

TMEM94 KMT2E PNPT1 KMT2C ADSL SACS DOCK8 RRM2B MACF1 HTT

1.31e-0344720710C3714756
DiseaseUnilateral agenesis of kidney

FREM2 FRAS1

1.33e-0382072C0266294
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3

1.33e-0382072DOID:0060308 (implicated_via_orthology)
DiseaseColorectal Carcinoma

EPHB6 ESR2 ABCA10 SLC12A5 KMT2C SACS DNAH8 DNAH3 LAMB3 ITPRID1 TYMP ABCA6 VRTN

1.46e-0370220713C0009402
Diseaseurate measurement, bone density

ASIC2 DOCK5 SULF1 ADAMTS16 NAV1 DNAH8 SLC30A10 FRAS1 AHCTF1 HMGXB4 PRKDC JHY

1.51e-0361920712EFO_0003923, EFO_0004531
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

INHBC NLRC5 PRKAG3 ABCA6 DOCK7 MACF1 HTT

1.55e-032392077EFO_0008317, EFO_0020945
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGB1 PCDHGA9 KSR2 PCDHGC3

1.58e-03712074EFO_0007878, EFO_0007979
Diseasetriglycerides to total lipids in small HDL percentage

INHBC NLRC5 PRKAG3 DOCK7

1.67e-03722074EFO_0022336
Diseasecholesteryl ester measurement, high density lipoprotein cholesterol measurement

INHBC DGKQ SULF2 NLRC5 KIF16B PON3 PRKAG3 DOCK7

1.70e-033122078EFO_0004612, EFO_0010351
Diseasepost-operative acute kidney injury

CDH26 CAPRIN1

1.71e-0392072EFO_0009955
DiseaseUterine Neoplasms

BAP1 CSF3

1.71e-0392072C0042138
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

INHBC LACTB NLRC5 PON3 PRKAG3 DOCK7 MACF1

1.71e-032432077EFO_0004612, EFO_0020944
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

DGKQ SULF2 NLRC5 KNL1 PON3 PRKAG3 ABCA6 DOCK7

1.80e-033152078EFO_0004612, EFO_0008591
Diseasetotal cholesterol measurement, high density lipoprotein cholesterol measurement

INHBC DGKQ SULF2 NLRC5 KIF16B PON3 PRKAG3 DOCK7

1.80e-033152078EFO_0004574, EFO_0004612
Diseasefree cholesterol to total lipids in large LDL percentage

PRKAG3 ABCA6 DOCK7 MACF1

1.84e-03742074EFO_0022280
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

INHBC DGKQ SULF2 NLRC5 KNL1 PON3 PRKAG3 DOCK7

2.03e-033212078EFO_0004612, EFO_0004639
DiseaseUterine Cancer

BAP1 CSF3

2.12e-03102072C0153567
DiseaseDevelopmental delay (disorder)

SPART PNPT1 NBAS

2.22e-03372073C0424605
Diseasecortical thickness

HDAC9 ASIC2 ADGRV1 DYSF AFAP1L1 NELL2 SULF2 BPGM NAV1 ABCC10 FNIP2 SYT2 ITIH5 IFTAP DOCK7 MACF1 FIGLA

2.30e-03111320717EFO_0004840
Diseaseresponse to vaccine, cytokine measurement

DCHS2 MNAT1 DNAH3 THEMIS SLC4A5

2.36e-031312075EFO_0004645, EFO_0004873
Diseaselipid measurement, high density lipoprotein cholesterol measurement

INHBC DGKQ SULF2 NLRC5 KNL1 PON3 PRKAG3 DOCK7

2.40e-033302078EFO_0004529, EFO_0004612
DiseaseGlobal developmental delay

TMEM94 SPART KMT2E PNPT1 NBAS

2.52e-031332075C0557874
DiseaseHodgkins lymphoma

SERPINF2 THEMIS KIF16B BRME1

2.69e-03822074EFO_0000183
Diseasecholesterol in very small VLDL measurement

ABCA10 ABCA6 DOCK7

2.78e-03402073EFO_0022231
DiseaseCarcinoma, Transitional Cell

ESR2 KMT2C CSF3

2.98e-03412073C0007138
DiseaseCharcot-Marie-Tooth disease (is_implicated_in)

ITPR3 SLC12A6

3.09e-03122072DOID:10595 (is_implicated_in)
DiseaseBladder Neoplasm

ESR2 BAP1 KMT2C TYMP CSF3

3.14e-031402075C0005695
Diseaseoral microbiome measurement

HDAC9 KMT2C FRAS1

3.19e-03422073EFO_0801229
DiseaseMalignant neoplasm of urinary bladder

ESR2 BAP1 KMT2C TYMP CSF3

3.24e-031412075C0005684
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

CDH23 PNPT1

3.63e-03132072C1846647
Diseasecholesterol in medium VLDL measurement

ABCA10 ABCA6 DOCK7

3.65e-03442073EFO_0022225
Diseasetotal lipids in very small VLDL measurement

ABCA10 ABCA6 DOCK7

3.89e-03452073EFO_0022156
Diseasenevus count, cutaneous melanoma

RTEL1 ADGRV1 DOCK8 SMIM44

3.91e-03912074EFO_0000389, EFO_0004632
Diseaseneutrophil percentage of leukocytes

HDAC9 CDH23 NLRC5 CRTC3 DOCK8 GTF3C1 CSF3 SBNO1 AKAP11 PRKDC HTT

4.06e-0361020711EFO_0007990
DiseaseManganese Poisoning

SLC30A10 HTT

4.22e-03142072C0677050
Diseasefree cholesterol in small VLDL measurement

ABCA10 ABCA6 DOCK7

4.40e-03472073EFO_0022272
Diseasefree cholesterol in very small VLDL measurement

ABCA10 ABCA6 DOCK7

4.40e-03472073EFO_0022275
Diseasefree cholesterol in medium VLDL measurement

ABCA10 ABCA6 DOCK7

4.40e-03472073EFO_0022269
Diseaseautism spectrum disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3 ITPR3 UBE3A TMPRSS9

4.46e-031522075DOID:0060041 (implicated_via_orthology)
DiseaseParkinson's disease symptom measurement

PPP1R13L ADGRE2 ADAMTS16

4.67e-03482073EFO_0600011
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

HPS4 DOCK7

4.84e-03152072DOID:2223 (implicated_via_orthology)
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

NLRC5 PRKAG3 ABCA6 DOCK7 MACF1 HTT

4.93e-032222076EFO_0008317, EFO_0020943
Diseasecholesteryl esters to total lipids in small VLDL percentage

NLRC5 ABCA6 DOCK7

4.94e-03492073EFO_0022256
DiseaseHernia

PNPT1 HMCN2 ADAMTS16

5.53e-03512073HP_0100790
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

CDH23 OTOF MYO15A

5.53e-03512073cv:CN043650
Diseasephospholipids in very small VLDL measurement

ABCA10 ABCA6 DOCK7

5.53e-03512073EFO_0022300
Diseasecholesterol to total lipids in small VLDL percentage

NLRC5 ABCA6 DOCK7

5.53e-03512073EFO_0022242
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

DGKQ SULF2 NLRC5 PON3 PRKAG3 ABCA6 DOCK7

5.74e-033032077EFO_0004612, EFO_0020945
Diseasemean platelet volume

HDAC9 ANKMY1 SIRPG DOCK5 ESYT2 GP1BA SLC12A6 HDAC5 PCDHGB1 DOCK8 PCDHGA9 KIF16B DOCK7 PCDHGC3 HTT

5.78e-03102020715EFO_0004584
Diseasephospholipids in IDL measurement

ABCA10 ABCA6 DOCK7

5.84e-03522073EFO_0022164
DiseaseCarcinomatosis

PADI4 ESR2 TYMP CSF3 GLYCAM1

5.97e-031632075C0205699
DiseaseCarcinoma, Spindle-Cell

PADI4 ESR2 TYMP CSF3 GLYCAM1

5.97e-031632075C0205697
DiseaseUndifferentiated carcinoma

PADI4 ESR2 TYMP CSF3 GLYCAM1

5.97e-031632075C0205698
DiseaseAnaplastic carcinoma

PADI4 ESR2 TYMP CSF3 GLYCAM1

5.97e-031632075C0205696
Diseaseepilepsy (implicated_via_orthology)

SLC12A5 UBE3A SLC12A6 L1CAM SLC1A6

5.97e-031632075DOID:1826 (implicated_via_orthology)
DiseaseCarcinoma

PADI4 ESR2 TYMP CSF3 GLYCAM1

6.12e-031642075C0007097
Diseasecholesterol in small VLDL measurement

ABCA10 ABCA6 DOCK7

6.16e-03532073EFO_0022228
Diseaseceramide measurement

HDAC9 ESR2 ANKMY1 MDN1 RRM2B KIF16B

6.46e-032352076EFO_0010222
DiseasePeripheral Nervous System Diseases

SLC12A6 CSF3 SERPINB2

6.49e-03542073C4721453
Diseaseleukemia

KMT2E PPP1R13L BAP1

6.83e-03552073C0023418
Diseasehepcidin:ferritin ratio

TMCO5B THEMIS IFTAP

6.83e-03552073EFO_0007901
Diseasecystitis (biomarker_via_orthology)

ESR2 CSF3

6.96e-03182072DOID:1679 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
IDIIQPALVLATGDL

TMEM62

86

Q0P6H9
PVLDVLAALLRQGEE

URB2

1321

Q14146
PGLNGLSDTIILDII

ESYT2

341

A0FGR8
LLDAGIVAELQAPDL

ADCK2

491

Q7Z695
IAPVTLTLGSLLDDQ

CNTNAP3

256

Q9BZ76
ALATGEELPELTLLT

ARHGEF25

111

Q86VW2
EELPELTLLTTLLEG

ARHGEF25

116

Q86VW2
VVSLLLENGADPSLE

ANKRD34C

101

P0C6C1
VVTGPALAEIDLQEL

ANAPC2

781

Q9UJX6
DVILDPDTANAILLV

BTN3A3

341

O00478
LLENTPVLEDVLGRI

CEP68

696

Q76N32
VLSILGNPSVVLLDE

ABCA10

1351

Q8WWZ4
SGLPEDTVLLLLNAI

SERPINF2

221

P08697
SDILQALVLSPAGID

PRKAG3

471

Q9UGI9
LLQDGSPILLSDVIS

ADGRE2

436

Q9UHX3
LVNDQLGLVDSLIPL

BPIFB4

341

P59827
GILPISQESLLLGDV

ADD3

246

Q9UEY8
LILLDGTIQGDPLDL

ATP13A4

536

Q4VNC1
EALESQTLLGPLELV

GSDMD

391

P57764
QTLLGPLELVGSLLE

GSDMD

396

P57764
GITILGDPQILLLDE

ABCA6

626

Q8N139
PGETIQTLLLEVLAD

ADGRV1

2296

Q8WXG9
LPEVVELGILDQLST

ARHGEF16

266

Q5VV41
SQEFPLGIELLLNVL

ANKRD13C

456

Q8N6S4
VVLEVLPLLGRQAES

DGKQ

426

P52824
LELESDPGLFTLLVE

BAP1

6

Q92560
IQDLAAVSLELPDIL

AKAP11

71

Q9UKA4
SLAILDVESGLLPQL

GLYCAM1

16

Q8IVK1
DVESGLLPQLSVLLS

GLYCAM1

21

Q8IVK1
LLQAEDLGPDTLDSL

AP5Z1

31

O43299
VALLPALVDAGTALE

AP5Z1

451

O43299
GLALQALDTLPDSLE

AHDC1

311

Q5TGY3
PDISLLDRDNVGLVL

ANGEL2

276

Q5VTE6
LLEQALELLPGFQEV

CFAP73

146

A6NFT4
GLNGVPILSEEELSL

CAPRIN1

171

Q14444
VLLDEGPDTLNTSLI

CDH23

1641

Q9H251
DLLPLIGSNNVLLEE

ADAMTS14

831

Q8WXS8
GLILLEDEQPGLVIS

ADAMTS16

341

Q8TE57
GELLALLDVNLQIPD

ASIC2

111

Q16515
LIGIDDDLLSTGIIL

KIF16B

456

Q96L93
LEALNRDLVPTGVLV

RABL3

111

Q5HYI8
ENLLRTIELGLEVSP

ISYNA1

246

Q9NPH2
GIDIITALILNDISP

ITPR3

1966

Q14573
GIDTTELLQSLPDEL

KCNH3

551

Q9ULD8
LPEDLAEALASGVIL

LRCH4

556

O75427
ELGLAESDIIDIPQL

PADI4

556

Q9UM07
LSLLVGFLEEGQEPL

ABCC10

306

Q5T3U5
ILLGIPETEGLETAL

OR10D4P

11

Q8NGN7
VDLNDISPLGLATVI

KLHL31

111

Q9H511
VSVLIPLLENGELLI

MDN1

411

Q9NU22
VTILDQEAAGSLILP

FRAS1

3146

Q86XX4
LVEPDGQLILDDSLI

FRAS1

3851

Q86XX4
DELSLVGLPDAIDIQ

KMT2C

226

Q8NEZ4
ELESSDLPVALLLAQ

MNAT1

186

P51948
DALSPEQLVLTLLEA

ESR2

261

Q92731
EESLPEISLLEILQN

JHY

746

Q6NUN7
EAGGQLVIPLDELTL

NEK1

761

Q96PY6
PSLQIDVLTELELGE

NELL2

26

Q99435
ILESAGIASLEVLPL

ITIH5

191

Q86UX2
REGILLQLEVLTAEP

ITPRID1

936

Q6ZRS4
LEVPAELAGLLQAVA

MYO15A

2001

Q9UKN7
PLLTVQEGAVEDLIL

MTO1

146

Q9Y2Z2
LADLSLEISGIIPTD

HMCN2

566

Q8NDA2
GPTLELESQRELLLD

INHBC

31

P55103
ALSLGDVARILEPVL

DOP1B

986

Q9Y3R5
LEEISPGQLSLEDLL

KSR2

106

Q6VAB6
GASSVLLVLPEELDT

LACTB

491

P83111
SLLALLLPLGAVEEQ

FICD

36

Q9BVA6
LPLVVEELLGTSNAL

FREM2

186

Q5SZK8
LVLSLLAEEPLLGDS

HPS4

551

Q9NQG7
VQDLLLLDVTPLSLG

HSPA2

391

P54652
GALTLEQPELVESLS

LRRC36

16

Q1X8D7
ILLGLTNDSELQVPL

OR5B3

11

Q8NH48
LQGIIDDLVVLTAEP

MTSS2

221

Q765P7
DSIPDILADLGSLQI

PCDHGA9

666

Q9Y5G4
ILADLGSLQIPADLE

PCDHGA9

671

Q9Y5G4
QIPEDSDLGTVIALI

PCDHGB1

351

Q9Y5G3
VSDPVLLEILGQASD

DNAH8

1586

Q96JB1
PLDLSNLSLEGIAVL

DGKA

586

P23743
SDLQLGLDAVEPTAL

KMT2E

1021

Q8IZD2
LSLPETETGENLLLI

KNL1

106

Q8NG31
PELEGIEILNSSAVL

L1CAM

816

P32004
EEAERILPGILNDTL

KLHL40

296

Q2TBA0
TINESLLVPLALEID

KRT82

96

Q9NSB4
SLSLLPELTDNGLVA

LRRC29

106

Q8WV35
VLDLSPSRIILGLQD

LRIT3

186

Q3SXY7
VPILLELDENLRAVG

BPGM

216

P07738
NLDLSGLEPILVESD

HMGXB4

281

Q9UGU5
LLLGVTDIQELQPFL

OR12D2

11

P58182
PLGTVIALLSVTDLD

PCDHGC3

366

Q9UN70
RIAQDLGLELAELVP

PCDHA5

46

Q9Y5H7
IFTEQELELLISGLP

HUWE1

4241

Q7Z6Z7
ELELLISGLPTIDID

HUWE1

4246

Q7Z6Z7
PGLLVLCDNLVTLET

NBAS

876

A2RRP1
IENAVESGRALLPIL

PDP1

176

Q9P0J1
LNSVGDLLDLIPSLS

PLBD1

196

Q6P4A8
SPVLILDLISGDDDL

EXOC7

166

Q9UPT5
EVPLDLEVLLLSTFG

NLRC5

81

Q86WI3
PLELLEEATLNVLSA

MACF1

2281

Q9UPN3
STLGLVDVADQPELI

MACF1

2431

Q9UPN3
RLETVALPLQGLEDL

MACF1

4771

Q9UPN3
NVEELRTEGLPLGLI

GRIN3A

361

Q8TCU5
LLLGVTDIQELQPFL

OR12D1

11

P0DN82
NPDLRALTLVEIGIE

DCHS2

2526

Q6V1P9
VILPQVLLGLRDTSD

SCYL3

376

Q8IZE3
IDLLNSPDLLEATIG

EPB41L5

451

Q9HCM4
LEEVEQLLRDLGILP

FHAD1

616

B1AJZ9
LLNVLLGLLVPVEDE

HTT

291

P42858
LLGATEILQADLLPD

IL5RA

11

Q01344
LLLLPGEVEQDVSTS

IFTAP

121

Q86VG3
LLVETLGVPLQEATE

BRME1

146

Q0VDD7
EVLLPLLTDQLSGQL

DOCK5

876

Q9H7D0
LAGLVLTELAVILDP

DOCK7

1186

Q96N67
LTELAVILDPDAEGL

DOCK7

1191

Q96N67
GLLRLEISTAPEIIN

DOCK8

506

Q8NF50
LEVNLEEIPGEGLLI

C2CD2L

191

O14523
LGTPVLIENIGEELD

DNAH3

3121

Q8TD57
LEEELQIEPLSLDGL

CRTC3

581

Q6UUV7
VVLGIESNDLPLLTA

FNIP2

1086

Q9P278
VVLIPGLISGLEEDQ

AVL9

381

Q8NBF6
EGLLPRLLSLSNVEE

ARFGEF3

681

Q5TH69
SGQLPEELFLLLQSL

F8A1;

311

P23610
EQLLVSGQPLLIFLE

GPAT2

276

Q6NUI2
ALPGEEGVQIVELLL

ANKMY1

591

Q9P2S6
ELELQEAELTLPSLG

SLC1A6

526

P48664
LQVDGTLPVLGTLDL

GP1BA

86

P07359
SLEQELQPDLLDSLG

CDH26

801

Q8IXH8
ELGPTLDTLQLDVAD

CSF3

131

P09919
GPELAITLLLAVLTE

DENND4B

406

O75064
TLQGLQLDLPLEEET

LAMB3

661

Q13751
LGEIQVVDAASLLAP

ENGASE

601

Q8NFI3
PEVTLQALGEDEITL

AHCTF1

16

Q8WYP5
ALLGTPQAEVLEDVL

FIGLA

16

Q6QHK4
ALLSVELQPLDEAVL

HDAC5

1021

Q9UQL6
ALLGNELEPLAEDIL

HDAC9

971

Q9UKV0
PLLAEAGDVLELIIS

GRIP2

1006

Q9C0E4
EEELLLLQPELQGGL

PPP1R18

586

Q6NYC8
ELGILIASLDLVAPI

SLC12A6

631

Q9UHW9
NEIEVEGLPLLITLD

SACS

3146

Q9NZJ4
VPLSALELGLETEAA

SBNO1

46

A3KN83
DVSLLSPGEDVLIDI

DYSF

1446

O75923
NPLVLLLDAALTGEL

PPP1R13L

626

Q8WUF5
GLLSPEEDQSLLLSQ

NOC4L

156

Q9BVI4
PSVVLLDDLDLIAGL

PEX1

656

O43933
IAPVTLTLGSLLDDQ

CNTNAP3B

256

Q96NU0
LGLAVEIVDTSNPEL

OTOF

571

Q9HC10
GILIASLDEVAPILS

SLC12A5

571

Q9H2X9
DIEVRTPADNGLILL

LAMA4

1076

Q16363
ENVQDLLLLDVTPLS

HSPA8

386

P11142
LLLPDEIADVSTGLE

SERPINB2

266

P05120
TGIGDVPLVILLDDL

NAV1

1616

Q8NEY1
VPLVILLDDLSEAGS

NAV1

1621

Q8NEY1
GDLLLQQAELPLSTE

FREM3

611

P0C091
ELLLGLLELIEEPSG

GLMN

101

Q92990
ILELQEQLTGLIPSD

RUNDC3A

311

Q59EK9
ILLRLEGAIDAVELP

RTEL1

321

Q9NZ71
LTVGVLQAAELPALD

SYT2

156

Q8N9I0
ALILGENVSLPETLI

UTP20

371

O75691
EGLLSDPLSDLQLVS

RAB11FIP1

931

Q6WKZ4
AQIGADIALLELEEP

TPSAB1

116

Q15661
AQIGADIALLELEEP

TPSB2

116

P20231
GADIALLELEEPVNI

TPSD1

126

Q9BZJ3
DLLVDVLPLVLSRGT

TMCO5B

271

A8MYB1
AVILGDQLTAADLVP

PPP4R1

691

Q8TF05
ELLRSLAEELPLEQG

PLCD4

76

Q9BRC7
EELSQDPVLELSGGL

GIMAP6

16

Q6P9H5
GLILAEILSRLEPVS

IQCA1L

136

A6NCM1
EFLLLGISEEPELQA

OR7A10

11

O76100
AQLSLEDLPALGITL

EPHB6

981

O15197
LAEAEQTLGLPITDE

ADSL

46

P30566
ALPDGLSVEDILNLL

SCG2

426

P13521
ASEGLLNTPDILQLL

SHOC1

871

Q5VXU9
LTNGVLVESLSEEPL

RNF169

601

Q8NCN4
VTLEARAPLENLGLV

SEMA4C

651

Q9C0C4
LLAVDGVNEPDVLAI

PNPT1

156

Q8TCS8
LLTLLLGLTEVAGEE

SIRPG

16

Q9P1W8
TDNLEVILLGLLVPA

SLC10A5

331

Q5PT55
LLGLSDDPDLQIVIF

OR6C3

11

Q9NZP0
LELELTPQGTLAERI

OXCT2

131

Q9BYC2
EELPSNILLVRLLDG

SH3RF1

61

Q7Z6J0
ILDNPTLTLEVLNEA

TGM3

591

Q08188
ELERLAGLEQAILSP

EIF4ENIF1

361

Q9NRA8
VLEQLLPELTGLLSL

AFAP1L1

6

Q8TED9
GLEEELADILQGPSL

CLCN1

961

P35523
IEQEFLTEALPVGLI

RRM2B

261

Q7LG56
AALDLGVQLTPETLV

TNRC18

1241

O15417
LSIEEDVLAATPGLQ

THEMIS

466

Q8N1K5
DDPELVLIVGVLGLL

SLC30A10

111

Q6XR72
LQGVEVALAPEELEL

SF3B2

821

Q13435
LETLGLDADELILIP

SPART

211

Q8N0X7
IPESSELTLQELLGE

UBE3A

401

Q05086
LSPDEQGVDILIVLI

TMPRSS11F

116

Q6ZWK6
ETDSSLILDVPLGVI

MTM1

76

Q13496
NSLLPESGIVADIEL

TFE3

41

P19532
LSLLVLLPDDGVELS

SERPINB9

226

P50453
NLPVSLLVEGDIIAL

TMEM94

176

Q12767
REASPLQSLLEVLGL

SLC39A7

441

Q92504
PLTENSLLEVLDGAV

RNF123

741

Q5XPI4
RPLQTLSLGLEEELL

TMPRSS9

96

Q7Z410
LGPLTEILEGVLQAD

NUP188

1181

Q5SRE5
LDLDSGSLPQIIDDV

SLC4A5

176

Q9BY07
PSLTGEDLEGLDLQL

SMIM44

86

A0A286YF18
LVDNLTVDPATGDIL

PON3

266

Q15166
LLALEPGILDTANVE

VASN

181

Q6EMK4
TVALLEAILDGIVDP

PRKDC

1006

P78527
ELLVLEQFLSILPGE

ZNF445

96

P59923
ELLVLEQFLTVLPGE

ZNF213

86

O14771
EIDGQALLLLTLPTV

SFMBT1

821

Q9UHJ3
LIELLDPSILSAGQS

VEZT

111

Q9HBM0
PVAVLELLQGLESLG

GTF3C1

2031

Q12789
PGLQVLEVDSVALSL

VRTN

51

Q9H8Y1
NIDLAPTILDIAGLD

SULF1

361

Q8IWU6
LLSEDLQGDIPENIL

ZFYVE26

106

Q68DK2
DGTVELVRALPLALV

TYMP

386

P19971
LILLPEDINGLEQLE

SERPINB10

251

P48595
LNIDLAPTILDIAGL

SULF2

361

Q8IWU5
LLTPVLANILEADQE

TBK1

276

Q9UHD2
ELLVLEQFLTVLPGE

ZNF500

91

O60304
EQALRLGSAPEVLLV

TRIM3

256

O75382
ILLSIQSLLGEPNID

UBE2C

131

O00762
RETELLLGTLLQPAV

UTF1

66

Q5T230
ELLLEGAETVTPVLD

LTB

176

Q06643
DDVESNLLLPAGIAL

MYOF

341

Q9NZM1