Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ARHGAP30 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.93e-08	279	102	12	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ARHGEF18 ARHGAP30 TBC1D3C TBC1D3B GNA13 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.98e-07	507	102	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ARHGEF18 ARHGAP30 TBC1D3C TBC1D3B GNA13 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.98e-07	507	102	14	GO:0030695
GeneOntologyMolecularFunction	molecular function activator activity	SEMA6C TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D WNT1 ARHGAP30 IL31 SEMA3G TBC1D3C TBC1D3B FBN1 FBN2 LRRC26 TBC1D3I TBC1D3G AGRN TBC1D3K TBC1D3F	3.59e-06	1233	102	20	GO:0140677
GeneOntologyMolecularFunction	calcium ion binding	PCDHGB5 LRP1B CD93 FBN1 FBN2 MEGF8 PCDHGB4 LRP4 AGRN FBN3 NOTCH2 NOTCH4 RAB11FIP3	1.13e-04	749	102	13	GO:0005509
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D ARHGAP30 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.30e-04	656	102	12	GO:0008047
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PIP5K1A TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.05e-13	109	101	12	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PIP5K1A TBC1D3I TBC1D3G AGRN TBC1D3K TBC1D3F	2.10e-10	244	101	13	GO:0043547
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PIP5K1A TBC1D3I TBC1D3G AGRN TBC1D3K TBC1D3F	9.81e-09	335	101	13	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PIP5K1A TBC1D3I TBC1D3G AGRN TBC1D3K TBC1D3F	9.77e-07	499	101	13	GO:0051345
GeneOntologyBiologicalProcess	positive regulation of receptor clustering	ZDHHC2 LRP4 LRP5 AGRN	1.98e-06	19	101	4	GO:1903911
GeneOntologyBiologicalProcess	positive regulation of molecular function	TBC1D3E TRAF2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D WNT1 WRAP53 TBC1D3C TBC1D3B FBN1 LRRC26 LRP5 PIP5K1A PLCL1 TBC1D3I TBC1D3G AGRN NOTCH2 TBC1D3K TBC1D3F	4.76e-06	1430	101	21	GO:0044093
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	TBC1D3E TRAF2 TBC1D3 TBC1D3H TBC1D3L TBC1D3D WRAP53 TBC1D3C TBC1D3B FBN1 PIP5K1A TBC1D3I TBC1D3G AGRN NOTCH2 TBC1D3K TBC1D3F	9.67e-06	1028	101	17	GO:0043085
GeneOntologyBiologicalProcess	regulation of receptor clustering	ZDHHC2 LRP4 LRP5 AGRN	1.17e-05	29	101	4	GO:1903909
GeneOntologyBiologicalProcess	positive regulation of skeletal muscle acetylcholine-gated channel clustering	LRP4 LRP5 AGRN	2.43e-05	12	101	3	GO:1904395
GeneOntologyBiologicalProcess	regulation of skeletal muscle acetylcholine-gated channel clustering	LRP4 LRP5 AGRN	4.97e-05	15	101	3	GO:1904393
GeneOntologyBiologicalProcess	branching morphogenesis of an epithelial tube	TMEM67 WNT1 GZF1 GNA13 PKD1 LRP5 NOTCH4	5.42e-05	198	101	7	GO:0048754
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN1 FBN2	1.42e-04	4	101	2	GO:0035583
GeneOntologyBiologicalProcess	skeletal muscle acetylcholine-gated channel clustering	LRP4 LRP5 AGRN	1.42e-04	21	101	3	GO:0071340
GeneOntologyBiologicalProcess	morphogenesis of a branching epithelium	TMEM67 WNT1 GZF1 GNA13 PKD1 LRP5 NOTCH4	1.62e-04	236	101	7	GO:0061138
GeneOntologyBiologicalProcess	postsynaptic membrane organization	ZDHHC2 LRP4 LRP5 AGRN	1.64e-04	56	101	4	GO:0001941
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	TMEM67 WNT1 GZF1 MEGF8 GNA13 PKD1 LRP5 NOTCH2 NOTCH4	2.25e-04	421	101	9	GO:0060562
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	TMEM67 WNT1 GZF1 GNA13 PKD1 LRP5 NOTCH4	2.80e-04	258	101	7	GO:0001763
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PIP5K1A TBC1D3I TBC1D3G AGRN TBC1D3K TBC1D3F	3.52e-04	878	101	13	GO:0051336
GeneOntologyCellularComponent	microfibril	FBN1 FBN2 FBN3	3.02e-05	13	101	3	GO:0001527
GeneOntologyCellularComponent	postsynaptic recycling endosome membrane	ZDHHC2 RAB11FIP3	3.42e-04	6	101	2	GO:0098944
HumanPheno	Kyphoscoliosis	FBN1 FBN2 GZF1 MEGF8 LRP5 AGRN NOTCH2 MVK	8.91e-06	196	29	8	HP:0002751
HumanPheno	Blue sclerae	WNT1 ZNF469 FBN1 MEGF8 LRP5 MVK	2.52e-05	108	29	6	HP:0000592
HumanPheno	Kyphosis	WNT1 ZNF407 FBN1 FBN2 GZF1 MEGF8 LRP4 LRP5 AGRN NOTCH2 MVK	5.87e-05	510	29	11	HP:0002808
HumanPheno	Abnormal upper to lower segment ratio	FBN1 FBN2	9.36e-05	3	29	2	HP:0012772
HumanPheno	Mandibular pain	SCN9A LRP5	9.36e-05	3	29	2	HP:0200025
HumanPheno	Abnormal sclera morphology	WNT1 ZNF469 FBN1 MEGF8 LRP5 MVK	1.14e-04	141	29	6	HP:0000591
HumanPheno	Abnormal hip bone morphology	TMEM67 ZNF407 ZNF469 FBN1 FBN2 MEGF8 SCN9A LRP4 LRP5 CEP152 AGRN HEATR3	1.15e-04	653	29	12	HP:0003272
HumanPheno	Abnormal cortical bone morphology	FBN1 SCN9A LRP4 LRP5 CEP152	1.31e-04	90	29	5	HP:0003103
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	7.61e-14	49	99	10	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.77e-13	53	99	10	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.64e-13	55	99	10	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.64e-13	55	99	10	IPR000195
Domain	EGF-like_Ca-bd_dom	LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 LRP5 AGRN FBN3 NOTCH2 NOTCH4	5.42e-11	124	99	11	IPR001881
Domain	EGF_CA	LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 LRP5 FBN3 NOTCH2 NOTCH4	1.16e-10	99	99	10	PS01187
Domain	EGF_CA	LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 FBN3 NOTCH2 NOTCH4	7.49e-10	86	99	9	PF07645
Domain	EGF_CA	LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 AGRN FBN3 NOTCH2 NOTCH4	9.29e-10	122	99	10	SM00179
Domain	EGF_Ca-bd_CS	LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 FBN3 NOTCH2 NOTCH4	2.22e-09	97	99	9	IPR018097
Domain	ASX_HYDROXYL	LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 FBN3 NOTCH2 NOTCH4	2.91e-09	100	99	9	PS00010
Domain	cEGF	LRP1B CD93 FBN1 FBN2 LRP4 FBN3	4.02e-09	26	99	6	IPR026823
Domain	cEGF	LRP1B CD93 FBN1 FBN2 LRP4 FBN3	4.02e-09	26	99	6	PF12662
Domain	EGF_3	SSPOP LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 LRP5 AGRN FBN3 NOTCH2 NOTCH4	4.19e-09	235	99	12	PS50026
Domain	EGF	LRP1B CD93 FBN1 FBN2 FCGBP MEGF8 LRP4 LRP5 AGRN FBN3 NOTCH2 NOTCH4	4.19e-09	235	99	12	SM00181
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 FBN3 NOTCH2 NOTCH4	4.90e-09	106	99	9	IPR000152
Domain	EGF-like_dom	LRP1B CD93 FBN1 FBN2 FCGBP MEGF8 LRP4 LRP5 AGRN FBN3 NOTCH2 NOTCH4	8.02e-09	249	99	12	IPR000742
Domain	Growth_fac_rcpt_	TMEM67 LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 FBN3 NOTCH2 NOTCH4	1.02e-08	156	99	10	IPR009030
Domain	EGF_1	SSPOP LRP1B FBN1 FBN2 MEGF8 LRP4 LRP5 USH2A AGRN FBN3 NOTCH2 NOTCH4	1.05e-08	255	99	12	PS00022
Domain	EGF_2	SSPOP LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 LRP5 AGRN FBN3 NOTCH2 NOTCH4	1.61e-08	265	99	12	PS01186
Domain	EGF-like_CS	LRP1B CD93 FBN1 FBN2 MEGF8 LRP4 LRP5 AGRN FBN3 NOTCH2 NOTCH4	1.37e-07	261	99	11	IPR013032
Domain	FBN	FBN1 FBN2 FBN3	1.44e-07	3	99	3	IPR011398
Domain	EGF	LRP1B CD93 LRP4 LRP5 AGRN FBN3 NOTCH2 NOTCH4	3.51e-07	126	99	8	PF00008
Domain	TB	FBN1 FBN2 FBN3	4.98e-06	7	99	3	PF00683
Domain	LDLRA_1	SSPOP LRP1B PKD1 LRP4 LRP5	5.40e-06	48	99	5	PS01209
Domain	LDLRA_2	SSPOP LRP1B PKD1 LRP4 LRP5	5.99e-06	49	99	5	PS50068
Domain	-	FBN1 FBN2 FBN3	7.94e-06	8	99	3	3.90.290.10
Domain	TB	FBN1 FBN2 FBN3	1.19e-05	9	99	3	PS51364
Domain	TB_dom	FBN1 FBN2 FBN3	1.19e-05	9	99	3	IPR017878
Domain	hEGF	FBN2 FBN3 NOTCH2 NOTCH4	1.38e-05	28	99	4	PF12661
Domain	Ldl_recept_b	LRP1B LRP4 LRP5	5.04e-05	14	99	3	PF00058
Domain	LDLRB	LRP1B LRP4 LRP5	5.04e-05	14	99	3	PS51120
Domain	-	LRP1B HHIPL2 LRP4 LRP5	5.30e-05	39	99	4	2.120.10.30
Domain	LDLR_class-A_CS	SSPOP LRP1B LRP4 LRP5	5.86e-05	40	99	4	IPR023415
Domain	LY	LRP1B LRP4 LRP5	6.28e-05	15	99	3	SM00135
Domain	LDLR_classB_rpt	LRP1B LRP4 LRP5	6.28e-05	15	99	3	IPR000033
Domain	Ldl_recept_a	SSPOP LRP1B LRP4 LRP5	9.37e-05	45	99	4	PF00057
Domain	-	SSPOP LRP1B LRP4 LRP5	1.02e-04	46	99	4	4.10.400.10
Domain	6-blade_b-propeller_TolB-like	LRP1B HHIPL2 LRP4 LRP5	1.02e-04	46	99	4	IPR011042
Domain	LDrepeatLR_classA_rpt	SSPOP LRP1B LRP4 LRP5	1.31e-04	49	99	4	IPR002172
Domain	LDLa	SSPOP LRP1B LRP4 LRP5	1.31e-04	49	99	4	SM00192
Domain	Notch	NOTCH2 NOTCH4	1.66e-04	4	99	2	IPR008297
Domain	NODP	NOTCH2 NOTCH4	1.66e-04	4	99	2	PF07684
Domain	Notch_NODP_dom	NOTCH2 NOTCH4	1.66e-04	4	99	2	IPR011656
Domain	Notch_NOD_dom	NOTCH2 NOTCH4	1.66e-04	4	99	2	IPR010660
Domain	NOD	NOTCH2 NOTCH4	1.66e-04	4	99	2	PF06816
Domain	NOD	NOTCH2 NOTCH4	1.66e-04	4	99	2	SM01338
Domain	NODP	NOTCH2 NOTCH4	1.66e-04	4	99	2	SM01339
Domain	LNR	NOTCH2 NOTCH4	2.75e-04	5	99	2	PS50258
Domain	EGF_LAM_2	MEGF8 USH2A AGRN	5.29e-04	30	99	3	PS50027
Domain	EGF_LAM_1	MEGF8 USH2A AGRN	5.29e-04	30	99	3	PS01248
Domain	Notch_dom	NOTCH2 NOTCH4	5.74e-04	7	99	2	IPR000800
Domain	Notch	NOTCH2 NOTCH4	5.74e-04	7	99	2	PF00066
Domain	NL	NOTCH2 NOTCH4	5.74e-04	7	99	2	SM00004
Domain	PSI	SEMA6C SEMA3G MEGF8	6.41e-04	32	99	3	PF01437
Domain	Plexin_repeat	SEMA6C SEMA3G MEGF8	6.41e-04	32	99	3	IPR002165
Domain	Laminin_EGF	MEGF8 USH2A AGRN	8.36e-04	35	99	3	PF00053
Domain	EGF_Lam	MEGF8 USH2A AGRN	8.36e-04	35	99	3	SM00180
Domain	Laminin_EGF	MEGF8 USH2A AGRN	1.07e-03	38	99	3	IPR002049
Domain	Cys-rich_flank_reg_C	LRIG1 LRRC26 PKD1 LRRN4	1.34e-03	90	99	4	IPR000483
Domain	LRRCT	LRIG1 LRRC26 PKD1 LRRN4	1.34e-03	90	99	4	SM00082
Domain	Fol_N	FCGBP AGRN	1.48e-03	11	99	2	IPR003645
Domain	FOLN	FCGBP AGRN	1.48e-03	11	99	2	SM00274
Domain	PSI	SEMA6C SEMA3G MEGF8	1.63e-03	44	99	3	IPR016201
Domain	TIL	SSPOP FCGBP	1.77e-03	12	99	2	PF01826
Domain	C8	SSPOP FCGBP	1.77e-03	12	99	2	PF08742
Domain	PSI	SEMA6C SEMA3G MEGF8	1.86e-03	46	99	3	SM00423
Domain	-	SEMA6C WDR31 WDR27 SEMA3G WRAP53 WDR91 WDCP	1.97e-03	333	99	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA6C WDR31 WDR27 SEMA3G WRAP53 WDR91 WDCP	2.04e-03	335	99	7	IPR015943
Domain	Unchr_dom_Cys-rich	SSPOP FCGBP	2.09e-03	13	99	2	IPR014853
Domain	C8	SSPOP FCGBP	2.09e-03	13	99	2	SM00832
Domain	LRR_8	LRRC59 LRIG1 LRRC26 PKD1 LRRN4	2.17e-03	171	99	5	PF13855
Domain	TIL_dom	SSPOP FCGBP	2.43e-03	14	99	2	IPR002919
Domain	Leu-rich_rpt_typical-subtyp	LRRC59 LRIG1 LRRC26 PKD1 LRRN4	2.52e-03	177	99	5	IPR003591
Domain	LRR_TYP	LRRC59 LRIG1 LRRC26 PKD1 LRRN4	2.52e-03	177	99	5	SM00369
Domain	SOLCAR	SLC25A35 SLC25A10 SLC25A38	2.79e-03	53	99	3	PS50920
Domain	-	SLC25A35 SLC25A10 SLC25A38	2.79e-03	53	99	3	1.50.40.10
Domain	Mitochondrial_sb/sol_carrier	SLC25A35 SLC25A10 SLC25A38	2.79e-03	53	99	3	IPR018108
Domain	Mito_carr	SLC25A35 SLC25A10 SLC25A38	2.79e-03	53	99	3	PF00153
Domain	Mt_carrier_dom	SLC25A35 SLC25A10 SLC25A38	2.79e-03	53	99	3	IPR023395
Domain	VWD	SSPOP FCGBP	3.18e-03	16	99	2	SM00216
Domain	VWF_type-D	SSPOP FCGBP	3.18e-03	16	99	2	IPR001846
Domain	VWFD	SSPOP FCGBP	3.18e-03	16	99	2	PS51233
Domain	VWD	SSPOP FCGBP	3.18e-03	16	99	2	PF00094
Domain	VWC_out	SSPOP FCGBP	4.48e-03	19	99	2	SM00215
Domain	Semaphorin	SEMA6C SEMA3G	4.97e-03	20	99	2	IPR027231
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K	1.15e-09	99	69	9	M46448
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	9.90e-29	11	104	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D LINC02693 TBC1D3B TBC1D3G TBC1D3F	6.22e-11	74	104	8	16625196
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN2 FBN3	1.04e-07	4	104	3	25034023
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	1.04e-07	4	104	3	12359748
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	1.04e-07	4	104	3	8406013
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	2.59e-07	5	104	3	12604796
Pubmed	Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.	WNT1 LRP1B LRP4	2.59e-07	5	104	3	20383322
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	2.59e-07	5	104	3	8471161
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	ARHGEF18 FBN1 FBN2 FAM193A SCN9A CEP152 NOTCH2	1.43e-06	184	104	7	32908313
Pubmed	LRP4 serves as a coreceptor of agrin.	LRP4 LRP5 AGRN	1.44e-06	8	104	3	18957220
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP1B LRP4 LRP5	4.21e-06	11	104	3	24639464
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C ZNF628 ICE1 WRAP53 EFNA2 MEGF8 PKD1 LRP4 LRP5 HMGXB3 AGRN NOTCH2 CD276 RAB11FIP3	5.48e-06	1105	104	14	35748872
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	8.86e-06	2	104	2	12399449
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	8.86e-06	2	104	2	21851253
Pubmed	Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.	FBN1 FBN2	8.86e-06	2	104	2	12429739
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	8.86e-06	2	104	2	30044367
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	8.86e-06	2	104	2	21440062
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	8.86e-06	2	104	2	15131124
Pubmed	Notch receptors and hematopoiesis.	NOTCH2 NOTCH4	8.86e-06	2	104	2	11532344
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	8.86e-06	2	104	2	12524050
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	8.86e-06	2	104	2	20404337
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	8.86e-06	2	104	2	8791520
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	8.86e-06	2	104	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	8.86e-06	2	104	2	35419902
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	8.86e-06	2	104	2	8307578
Pubmed	Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navbeta4 peptide-mediated resurgent sodium currents.	SCN4B SCN9A	8.86e-06	2	104	2	21115638
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	8.86e-06	2	104	2	10504303
Pubmed	Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.	FBN1 FBN3	8.86e-06	2	104	2	15221638
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	8.86e-06	2	104	2	7744963
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	8.86e-06	2	104	2	26408953
Pubmed	The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis.	WNT1 LRP5	8.86e-06	2	104	2	16973609
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	8.86e-06	2	104	2	18006876
Pubmed	Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses.	LRP4 AGRN	8.86e-06	2	104	2	22854782
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	8.86e-06	2	104	2	24833718
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	8.86e-06	2	104	2	24265020
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	8.86e-06	2	104	2	20529844
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	8.86e-06	2	104	2	25524144
Pubmed	Notch4 and Wnt-1 proteins function to regulate branching morphogenesis of mammary epithelial cells in an opposing fashion.	WNT1 NOTCH4	8.86e-06	2	104	2	9576833
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	8.86e-06	2	104	2	23133647
Pubmed	notch2, notch4 gene polymorphisms in psoriasis vulgaris.	NOTCH2 NOTCH4	8.86e-06	2	104	2	23587900
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	8.86e-06	2	104	2	16407178
Pubmed	Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.	FBN1 FBN2	8.86e-06	2	104	2	1852206
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	8.86e-06	2	104	2	10359653
Pubmed	Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction.	NOTCH2 NOTCH4	8.86e-06	2	104	2	20643108
Pubmed	Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.	FBN1 FBN2	2.65e-05	3	104	2	10825173
Pubmed	A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.	FBN1 PKD1	2.65e-05	3	104	2	24071006
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	FBN1 FBN2	2.65e-05	3	104	2	30201140
Pubmed	MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters.	LRP4 AGRN	2.65e-05	3	104	2	24244707
Pubmed	Differential expression of Notch genes in human osteoblastic cells.	NOTCH2 NOTCH4	2.65e-05	3	104	2	11836628
Pubmed	Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK).	LRP4 AGRN	2.65e-05	3	104	2	21969364
Pubmed	Diversity of human copy number variation and multicopy genes.	TBC1D3E TBC1D3G	2.65e-05	3	104	2	21030649
Pubmed	Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor.	WNT1 LRP5	2.65e-05	3	104	2	11956231
Pubmed	Clonal variations among multiple primary mammary tumors and within a tumor of individual mice: insertion mutations of int oncogenes.	WNT1 NOTCH4	2.65e-05	3	104	2	7571419
Pubmed	Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.	WNT1 LRP5	2.65e-05	3	104	2	30404864
Pubmed	Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.	NOTCH2 NOTCH4	2.65e-05	3	104	2	11823422
Pubmed	Notch signaling: cell fate control and signal integration in development.	NOTCH2 NOTCH4	2.65e-05	3	104	2	10221902
Pubmed	Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.	FBN1 FBN2	2.65e-05	3	104	2	20855508
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP1B LRP4 LRP5	3.32e-05	21	104	3	21337463
Pubmed	Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.	WNT1 LRP5	5.29e-05	4	104	2	22696217
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 FBN2	5.29e-05	4	104	2	12429738
Pubmed	Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.	NOTCH2 NOTCH4	5.29e-05	4	104	2	28061457
Pubmed	The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.	NOTCH2 NOTCH4	5.29e-05	4	104	2	24145721
Pubmed	Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function.	LRP4 LRP5	5.29e-05	4	104	2	21471202
Pubmed	A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.	NOTCH2 NOTCH4	5.29e-05	4	104	2	20069356
Pubmed	Expression and clinical significance of Notch receptors in human renal cell carcinoma.	NOTCH2 NOTCH4	5.29e-05	4	104	2	19404845
Pubmed	Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.	NOTCH2 NOTCH4	5.29e-05	4	104	2	28669409
Pubmed	Human eye development is characterized by coordinated expression of fibrillin isoforms.	FBN1 FBN2	5.29e-05	4	104	2	25406291
Pubmed	Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.	FBN1 FBN2	5.29e-05	4	104	2	20729550
Pubmed	Evolutionary analysis of vertebrate Notch genes.	NOTCH2 NOTCH4	5.29e-05	4	104	2	11466531
Pubmed	Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.	NOTCH2 NOTCH4	5.29e-05	4	104	2	24151014
Pubmed	Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.	NOTCH2 NOTCH4	5.29e-05	4	104	2	11401408
Pubmed	The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase-LRP4 receptor complex by agrin at the neuromuscular junction.	LRP4 AGRN	5.29e-05	4	104	2	37356721
Pubmed	Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway.	WNT1 LRP5	5.29e-05	4	104	2	11336703
Pubmed	Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.	FBN1 FBN2	5.29e-05	4	104	2	16835936
Pubmed	Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.	NOTCH2 NOTCH4	5.29e-05	4	104	2	10194420
Pubmed	Functional conservation of mouse Notch receptor family members.	NOTCH2 NOTCH4	5.29e-05	4	104	2	8898100
Pubmed	Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.	WNT1 LRP5	5.29e-05	4	104	2	15064719
Pubmed	Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.	NOTCH2 NOTCH4	5.29e-05	4	104	2	11459941
Pubmed	Shh Plays an Inhibitory Role in Cusp Patterning by Regulation of Sostdc1.	LRP4 LRP5	5.29e-05	4	104	2	30325689
Pubmed	Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.	NOTCH2 NOTCH4	5.29e-05	4	104	2	18184405
Pubmed	Notch signaling in the mammalian central nervous system: insights from mouse mutants.	NOTCH2 NOTCH4	5.29e-05	4	104	2	15917835
Pubmed	Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.	NOTCH2 NOTCH4	5.29e-05	4	104	2	23444212
Pubmed	Deregulated expression of Notch receptors in human hepatocellular carcinoma.	NOTCH2 NOTCH4	5.29e-05	4	104	2	17920003
Pubmed	Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.	FBN1 FBN2	8.80e-05	5	104	2	26601954
Pubmed	Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.	NOTCH2 NOTCH4	8.80e-05	5	104	2	21726900
Pubmed	Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain.	WNT1 EFNA2	8.80e-05	5	104	2	10477297
Pubmed	A Japanese-specific allele in the GALNT11 gene.	FBN1 CEP152	8.80e-05	5	104	2	20547088
Pubmed	Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.	NOTCH2 NOTCH4	8.80e-05	5	104	2	21124806
Pubmed	Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6.	WNT1 LRP5	8.80e-05	5	104	2	11448771
Pubmed	Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice.	LRP4 AGRN	8.80e-05	5	104	2	31268420
Pubmed	Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin.	FBN1 FBN2	8.80e-05	5	104	2	12590922
Pubmed	Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).	NOTCH2 NOTCH4	8.80e-05	5	104	2	23675950
Pubmed	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.	NOTCH2 NOTCH4	8.80e-05	5	104	2	11101851
Pubmed	Chimeric analysis of Notch2 function: a role for Notch2 in the development of the roof plate of the mouse brain.	WNT1 NOTCH2	8.80e-05	5	104	2	12242712
Pubmed	Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.	FBN1 FBN2	8.80e-05	5	104	2	17255108
Pubmed	Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.	NOTCH2 NOTCH4	8.80e-05	5	104	2	15882997
Pubmed	POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.	FBN1 FBN2	8.80e-05	5	104	2	34411563
Pubmed	Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.	NOTCH2 NOTCH4	8.80e-05	5	104	2	27118257
Pubmed	A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.	WNT1 LRP5	8.80e-05	5	104	2	12121999
Pubmed	Development, composition, and structural arrangements of the ciliary zonule of the mouse.	FBN1 FBN2	8.80e-05	5	104	2	23493297
Interaction	IGFL3 interactions	TMEM67 LRP1B FBN2 LRP4 LRP5 AGRN NOTCH2	9.02e-08	75	100	7	int:IGFL3
Interaction	NTN5 interactions	LRP1B FBN1 FBN2 LRP4 NOTCH2	1.07e-07	24	100	5	int:NTN5
Interaction	ZFP41 interactions	LRP1B FBN1 FBN2 LRP4 AGRN NOTCH2	3.79e-07	57	100	6	int:ZFP41
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	4.98e-14	149	104	11	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F	3.27e-06	99	104	5	17q12
Cytoband	2q35	PNKD RESP18 DNPEP	7.88e-04	79	104	3	2q35
GeneFamily	Low density lipoprotein receptors	LRP1B LRP4 LRP5	1.12e-05	13	63	3	634
GeneFamily	Aminopeptidases\|CD molecules	METAP2 DNPEP	1.57e-03	17	63	2	104
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA6C SEMA3G	2.18e-03	20	63	2	736
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	4.45e-10	90	101	9	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B FBN2 TBC1D3G AGRN FBN3 TBC1D3K TBC1D3F	9.55e-09	281	101	12	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B FBN2 TBC1D3G AGRN FBN3 TBC1D3K TBC1D3F	9.55e-09	281	101	12	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B VENTX TBC1D3G TBC1D3K TBC1D3F	7.25e-08	213	101	10	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B VENTX TBC1D3G TBC1D3K TBC1D3F	7.25e-08	213	101	10	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B VENTX TBC1D3G TBC1D3K TBC1D3F	2.38e-07	242	101	10	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	ZDHHC2 SEMA6C TBC1D3 TBC1D3H TBC1D3L TBC1D3D TRO WDR27 TBC1D3C TBC1D3B VENTX EFNA2 FBN2 TBC1D3G AGRN FBN3 TBC1D3K TBC1D3F RAB11FIP3	1.84e-06	1153	101	19	PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	SEMA6C TBC1D3 TBC1D3H TBC1D3L TBC1D3D WNT1 TRO WDR27 TBC1D3C TBC1D3B EFNA2 FBN1 FBN2 PKD1 TBC1D3G AGRN FBN3 NOTCH2 TBC1D3K TBC1D3F	1.61e-05	1466	101	20	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	2.22e-05	320	101	9	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500	ZHX3 BACH2 FAM193A WDCP AGRN RAB11FIP3	7.90e-05	149	101	6	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D ICAM3 TBC1D3C TBC1D3B FBN1 SLC10A1 CHPT1 LRP4 TBC1D3G MVK TBC1D3K TBC1D3F	1.27e-04	1049	101	15	PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2 FBN3	2.93e-08	3	92	3	DOID:65 (implicated_via_orthology)
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	5.75e-05	4	92	2	DOID:0060249 (is_implicated_in)
Disease	autosomal dominant polycystic kidney disease (is_implicated_in)	PKD1 LRP5	5.75e-05	4	92	2	DOID:898 (is_implicated_in)
Disease	insomnia, insomnia measurement	CEP152 PLCL1	5.75e-05	4	92	2	EFO_0004698, EFO_0007876
Disease	polycystic liver disease (implicated_via_orthology)	PKD1 LRP5	2.00e-04	7	92	2	DOID:0050770 (implicated_via_orthology)
Disease	Familial thoracic aortic aneurysm and aortic dissection	FBN1 FBN2 PKD1	6.14e-04	53	92	3	C4707243
Disease	Connective Tissue Diseases	ZNF469 PKD1	7.33e-04	13	92	2	C0009782
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	PKD1 LRP5	8.54e-04	14	92	2	DOID:898 (implicated_via_orthology)
Disease	hip bone size	FAM193A PLCL1 AGRN	1.11e-03	65	92	3	EFO_0004844
Disease	Myasthenic Syndromes, Congenital, Slow Channel	LRP4 AGRN	1.12e-03	16	92	2	C0751885
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	TMEM67 PKD1	1.12e-03	16	92	2	DOID:0110861 (implicated_via_orthology)
Disease	Congenital Myasthenic Syndromes, Postsynaptic	LRP4 AGRN	1.27e-03	17	92	2	C0751883
Disease	cancer (implicated_via_orthology)	CBX7 PIP5K1A NOTCH2 MVK NOTCH4	1.54e-03	268	92	5	DOID:162 (implicated_via_orthology)
Disease	Congenital Myasthenic Syndromes, Presynaptic	LRP4 AGRN	1.59e-03	19	92	2	C0751884
Disease	CCL4 measurement	TBC1D3 TBC1D3F	1.76e-03	20	92	2	EFO_0004751
Disease	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	BACH2 FAM193A PLCL1 DNPEP	2.00e-03	170	92	4	EFO_0000685, EFO_0007791, EFO_0007837
Disease	leptin measurement	LRP1B CD93 GNA13	2.10e-03	81	92	3	EFO_0005000
Disease	Myasthenic Syndromes, Congenital	LRP4 AGRN	2.54e-03	24	92	2	C0751882
Disease	systemic scleroderma (is_implicated_in)	FBN1 NOTCH4	2.54e-03	24	92	2	DOID:418 (is_implicated_in)
Disease	Crohn's disease	BACH2 PNKD PLCL1 NOTCH2 NOTCH4 DNPEP	2.60e-03	441	92	6	EFO_0000384
Disease	mental development measurement	PCDHGB5 PCDHGB4	2.75e-03	25	92	2	EFO_0008230

Protein segments in the cluster

Peptide	Gene	Start	Entry
CSSEPCGFSSNGLIE	TDG	351	Q13569
PLCEFSSSPCSQGAR	BACH2	541	Q9BYV9
LLQGTFSGPSSCPLC	ARHGEF18	301	Q6ZSZ5
LSAGAIENACLPCSG	CEP152	1246	O94986
CALQALIDSCAGPGS	DNPEP	281	Q9ULA0
GCTECGARFSQPSAL	GZF1	436	Q9H116
RSADGLTASCLCPAT	AGRN	261	O00468
GPLCDSLCFNTQGSF	CD93	436	Q9NPY3
ATLCCSFSPEPGFSL	CD276	46	Q5ZPR3
GATPLFNACCSGSAA	ASB11	131	Q8WXH4
SFIAGGCATFLCQPL	SLC25A10	206	Q9UBX3
LFGTCTNSPGSFQCL	FBN3	1981	Q75N90
CNLRLPGSSDCAASA	FAM193A	1186	P78312
LASSCAGACGTSFPD	ASTL	26	Q6HA08
QAFCTFGSRLVSPGC	ATXN7L2	411	Q5T6C5
CILGSAEGTLCASPN	RBM20	451	Q5T481
LCNGQLGCSDPAFLT	RAB11FIP3	406	O75154
FCDLFPLLGLSCSST	OR8G2P	191	Q6IF36
DILCGDSSGALFPLC	PCDHGB4	776	Q9UN71
FLCAPLTGATSDCLG	MFSD10	101	Q14728
NTFSCLCLPGFTGDK	NOTCH2	931	Q04721
INSFSCLCPVGFTGS	NOTCH2	1006	Q04721
SVLGRPTCSCALGFT	LRP1B	4266	Q9NZR2
GLAFPTGCSLNNCAA	METAP2	216	P50579
SRTAAGSCPECQGSL	LRIG1	981	Q96JA1
GQPSGSLDSECASIC	GRXCR1	36	A8MXD5
LSCNKLTTLPSDFCG	LRRC59	46	Q96AG4
GIFTCTPSAGLSFCD	FNDC7	666	Q5VTL7
SLSSGCPAGCRLSFN	LINC02693	186	A8MQB3
EDNGGCSHLCLLSPS	LRP5	301	O75197
CGSSCFQSPGNLVTL	C9orf131	31	Q5VYM1
STQCLLCSSPLFKGG	HMGXB3	746	Q12766
GTCRPFAGSLADSCL	CSKMT	16	A8MUP2
LRGPESCSLGCAQAT	MEGF8	2111	Q7Z7M0
RLACVLGTPCFSSGQ	RFPL4B	131	Q6ZWI9
LSVCFPGCLLTSGEA	GNA13	11	Q14344
SSNGFQPCLALLCSP	MPND	376	Q8N594
LCGDSSGALFPLCNS	PCDHGB5	776	Q9Y5G0
LCSFLLGLGDSCFNT	MFSD11	356	O43934
CSEPLIELCSSGASG	PIP5K1A	166	Q99755
GGSLFVNCSTDCPSS	ICAM3	46	P32942
GTFLGLCSLLTGCES	PANK3	216	Q9H999
CGCSPGGNLSNVFSL	SLC10A1	96	Q14973
FLLLNSCPGGCSDTS	RESP18	61	Q5W5W9
FSECGGQLFSPLCLS	HEATR3	401	Q7Z4Q2
GPSTSVLFLFCCLGG	IL31	6	Q6EBC2
PGTAADLSRCQGCAS	ICE1	11	Q9Y2F5
ASSCGCTFQGLQLAP	FCGBP	796	Q9Y6R7
FALSGESCLPLASCG	FCGBP	1176	Q9Y6R7
FCGLLSSPTGPLSSC	FCGBP	2661	Q9Y6R7
FDLCLGGGNLSILCS	FCGBP	3891	Q9Y6R7
FKCLCPEGFSLSSSG	FBN1	2036	P35555
LCFSLTCPLGSGSPE	CBX7	101	O95931
FNACSQGSPSCAELL	ASB5	141	Q8WWX0
LCLFGAALCLTGSQA	LYPD5	11	Q6UWN5
TSNNSCSSPGGCRLF	EFNA2	186	O43921
TTDADCLGGICLPSS	KRTAP11-1	31	Q8IUC1
SCSPGTCQNLEGSFR	FBN2	2026	P35556
TPGSFSCECQRGFSL	FBN2	2591	P35556
CLGSTTSCAFPGLIS	HHIPL2	546	Q6UWX4
SGLAACGACVFTNPL	SLC25A35	6	Q3KQZ1
DSLTLCSGACPKASS	CCDC159	241	P0C7I6
INLFGNPLTCSCDLS	LRRN4	306	Q8WUT4
LCGAAQPSSASFACL	PKD1	231	P98161
QFVLAPSCCSLDSAG	ARHGAP30	581	Q7Z6I6
SRSCACSEPNILTGG	TMEM67	181	Q5HYA8
CSEPNILTGGLCFSS	TMEM67	186	Q5HYA8
CTSAGCTSSEPFLGQ	USH2A	3661	O75445
PSCLFSGDLLFLSGC	PNKD	246	Q8N490
AFPCCLSGFNISEGL	TDRD6	1631	O60522
HSLCFSPDGSQLFCG	WRAP53	281	Q9BUR4
SRALCSPSQLSCGSG	SSPOP	2461	A2VEC9
SPSQLSCGSGECLSA	SSPOP	2466	A2VEC9
GTEILLPCTFSSCFG	SCN4B	46	Q8IWT1
DALLCGFSTDSGQCP	SCN9A	311	Q15858
SGPCLCGLHLESSQF	TBC1D3L	531	B9A6J9
FPEPCANGGTCLSLS	NOTCH4	31	Q99466
PGSTCIDRVGSFSCL	NOTCH4	366	Q99466
FLCGSISGTCSTLLF	SLC25A38	31	Q96DW6
TNSCSPLGELFDHGC	CHPT1	121	Q8WUD6
SGPCLCGLHLESSQF	TBC1D3B	531	A6NDS4
SGPCLCGLHLESSQF	TBC1D3H	531	P0C7X1
FCLASILSSGPQNCA	TRAF2	56	Q12933
GAFSGPCASACLLFL	PRSS45P	236	Q7RTY3
QLACLSCGLSKAPSS	PLCL1	1056	Q15111
NLGLSACKGACPSSA	ZCWPW1	571	Q9H0M4
CGSRQLPSSVGLACF	nan	101	Q8N377
NLCFGGPPSTSACFS	TRO	1166	Q12816
SGPCLCGLHLESSQF	TBC1D3F	531	A6NER0
TSCGFDCLETSIGAP	MVK	361	Q03426
CLPGDSCSSSDSLIF	SPNS1	311	Q9H2V7
LLACGTNSFSPVCRS	SEMA6C	136	Q9H3T2
SGPCLCGLHLESSQF	TBC1D3E	531	A0A087X179
CEVCAASFRSGPGLS	ZNF469	2446	Q96JG9
AGRACNSSSPALDGC	WNT1	311	P04628
LLACGTGAFQPTCAL	SEMA3G	131	Q9NS98
SGPCLCGLHLESSQF	TBC1D3D	531	A0A087WVF3
SLGDGCSFPTCLVNQ	ZDHHC2	286	Q9UIJ5
RSCLTGNPFGTSACL	TBCCD1	261	Q9NVR7
FLSDCTVGGTCLPNA	ZNF407	116	Q9C0G0
DLSLIPNSACGCLSS	WDR27	301	A2RRH5
CLFTLSLDGSGPLTS	WDR31	316	Q8NA23
TGLAAPSLDTTGCCN	WDCP	701	Q9H6R7
SGPCLCGLHLESSQF	TBC1D3G	531	Q6DHY5
SGPCLCGLHLESSQF	TBC1D3	531	Q8IZP1
CSGCSFLAKTPEGLS	ZHX3	111	Q9H4I2
LACSPNGASFVCSAA	WDR91	501	A4D1P6
SGPCLCGLHLESSQF	TBC1D3K	531	A0A087X1G2
EALASAGASCCGQPL	VENTX	211	O95231
SGPCLCGLHLESSQF	TBC1D3I	531	A0A087WXS9
SGPCLCGLHLESSQF	TBC1D3C	531	Q6IPX1
FRCGSCDGSFPQLAS	ZNF628	386	Q5EBL2
SLASCLALGSGLTAC	LRRC26	276	Q2I0M4
FSCTCPTGINLLSDG	LRP4	1026	O75096