Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

LHX1 SP100 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

2.97e-1514127329GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 POU2F3 RAX SIX2 PROP1 CRX

3.44e-1214597326GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

PHOX2A CDX1 OTX1 OTX2 ALX1 MIXL1 PITX2 PITX3 POU1F1 SIX5 SIX1 PHOX2B POU2F3 RAX SIX2 PROP1 CRX

1.33e-115607317GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

PHOX2A CDX1 OTX1 OTX2 ALX1 MIXL1 PITX2 PITX3 POU1F1 SIX5 SIX1 PHOX2B POU2F3 RAX SIX2 PROP1 CRX

1.58e-115667317GO:0001216
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ZFHX4 MIXL1 PITX2 PITX3 NKX3-2 POU1F1 SIX5 ZFHX3 SIX1 PHOX2B EMX2 POU2F3 RAX SIX2 PROP1 CRX

6.62e-1112717323GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ZFHX4 MIXL1 PITX2 PITX3 NKX3-2 POU1F1 SIX5 ZFHX3 SIX1 PHOX2B EMX2 POU2F3 RAX SIX2 PROP1 CRX

3.00e-1012447322GO:0000978
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

CDX2 NKX6-2 PITX2 NKX3-2 ESX1 ZFHX3 PROP1

1.67e-04320737GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

CDX2 NKX6-2 PITX2 NKX3-2 ESX1 ZFHX3 PROP1

1.88e-04326737GO:0001217
GeneOntologyBiologicalProcesspattern specification process

SEMA3A LHX1 CDX1 OTX1 CDX2 OTX2 ALX1 LBX1 PITX2 NKX3-2 SIX1 EMX2 RAX SIX2 PROP1

3.12e-105267215GO:0007389
GeneOntologyBiologicalProcessregionalization

SEMA3A LHX1 CDX1 OTX1 CDX2 OTX2 ALX1 LBX1 PITX2 NKX3-2 SIX1 EMX2 SIX2 PROP1

9.33e-104787214GO:0003002
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

SP100 PHOX2A CDX1 OTX1 CDX2 OTX2 ALX1 MIXL1 PITX2 PITX3 POU1F1 SIX5 ZFHX3 SIX1 PHOX2B POU2F3 NOS1 RAX SIX2 PROP1 CRX

6.02e-0913907221GO:0045944
GeneOntologyBiologicalProcesshead development

PITPNM1 EPHB2 SEMA3A LHX1 PHOX2A OTX1 OTX2 SEMA6D PITX2 PITX3 POU1F1 LHX5 SIX1 PHOX2B EMX2 RAX PROP1

1.25e-089197217GO:0060322
GeneOntologyBiologicalProcesscentral nervous system development

PITPNM1 EPHB2 SEMA3A LHX1 PHOX2A OTX1 OTX2 NKX6-2 SEMA6D LBX1 PITX2 PITX3 POU1F1 LHX5 SIX1 PHOX2B EMX2 RAX PROP1

1.74e-0811977219GO:0007417
GeneOntologyBiologicalProcessdiencephalon development

SEMA3A OTX1 OTX2 PITX2 POU1F1 RAX PROP1

2.78e-0890727GO:0021536
GeneOntologyBiologicalProcessbrain development

PITPNM1 EPHB2 SEMA3A LHX1 PHOX2A OTX1 OTX2 SEMA6D PITX2 PITX3 POU1F1 LHX5 PHOX2B EMX2 RAX PROP1

3.29e-088597216GO:0007420
GeneOntologyBiologicalProcesssensory organ development

EPHB2 LHX1 OTX1 OTX2 PI4KB PITX2 PITX3 NKX3-2 SIX5 SIX1 PHOX2B RAX SIX2 CRX

1.91e-077307214GO:0007423
GeneOntologyBiologicalProcessembryonic organ morphogenesis

EPHB2 LHX1 OTX1 OTX2 ALX1 LBX1 PITX2 NKX3-2 SIX1 SIX2

3.77e-073517210GO:0048562
GeneOntologyBiologicalProcessembryonic organ development

EPHB2 LHX1 OTX1 CDX2 OTX2 ALX1 LBX1 PITX2 NKX3-2 ESX1 SIX1 SIX2

5.07e-075617212GO:0048568
GeneOntologyBiologicalProcesssomatotropin secreting cell differentiation

PITX2 POU1F1 PROP1

8.10e-076723GO:0060126
GeneOntologyBiologicalProcessdiencephalon morphogenesis

OTX1 OTX2 PROP1

8.10e-076723GO:0048852
GeneOntologyBiologicalProcessparasympathetic nervous system development

SEMA3A PHOX2A SIX1 PHOX2B

9.52e-0722724GO:0048486
GeneOntologyBiologicalProcessforebrain development

EPHB2 SEMA3A LHX1 OTX1 OTX2 PITX2 POU1F1 LHX5 EMX2 RAX PROP1

9.75e-074897211GO:0030900
GeneOntologyBiologicalProcessembryonic morphogenesis

EPHB2 LHX1 OTX1 OTX2 ALX1 LBX1 MIXL1 PITX2 NKX3-2 ESX1 SIX1 LBX2 SIX2

9.76e-077137213GO:0048598
GeneOntologyBiologicalProcessanimal organ morphogenesis

EPHB2 SEMA3A LHX1 CDX1 OTX1 CDX2 OTX2 ALX1 LBX1 PITX2 PITX3 NKX3-2 SIX1 EMX2 SIX2 PROP1 CRX

1.25e-0612697217GO:0009887
GeneOntologyBiologicalProcessanterior/posterior pattern specification

LHX1 CDX1 OTX1 CDX2 OTX2 ALX1 EMX2 SIX2

2.33e-06247728GO:0009952
GeneOntologyBiologicalProcessaxis specification

LHX1 CDX1 CDX2 OTX2 PITX2 SIX2

2.75e-06113726GO:0009798
GeneOntologyBiologicalProcesssensory organ morphogenesis

EPHB2 LHX1 OTX1 OTX2 PITX2 PITX3 NKX3-2 SIX1 SIX2

2.97e-06343729GO:0090596
GeneOntologyBiologicalProcesscranial nerve development

EPHB2 SEMA3A PHOX2A SIX1 PHOX2B

3.67e-0667725GO:0021545
GeneOntologyBiologicalProcessanterior/posterior axis specification

LHX1 CDX1 CDX2 OTX2 SIX2

3.95e-0668725GO:0009948
GeneOntologyBiologicalProcesshypothalamus development

SEMA3A PITX2 RAX PROP1

4.00e-0631724GO:0021854
GeneOntologyBiologicalProcesssegmentation

SEMA3A LHX1 CDX1 CDX2 OTX2 SIX1

4.51e-06123726GO:0035282
GeneOntologyBiologicalProcesscranial nerve morphogenesis

EPHB2 SEMA3A PHOX2A SIX1

4.56e-0632724GO:0021602
GeneOntologyBiologicalProcessear development

EPHB2 OTX1 OTX2 PI4KB NKX3-2 SIX1 PHOX2B SIX2

6.70e-06285728GO:0043583
GeneOntologyBiologicalProcessembryo development

EPHB2 SEMA3A LHX1 CDX1 OTX1 CDX2 OTX2 ALX1 LBX1 MIXL1 TTLL4 PITX2 NKX3-2 ESX1 SIX1 LBX2 SIX2

6.72e-0614377217GO:0009790
GeneOntologyBiologicalProcesssensory system development

EPHB2 SEMA3A LHX1 OTX2 PITX2 PITX3 SIX5 PHOX2B RAX CRX

7.63e-064917210GO:0048880
GeneOntologyBiologicalProcesshindbrain development

EPHB2 LHX1 PHOX2A OTX1 OTX2 LHX5 PHOX2B

8.11e-06208727GO:0030902
GeneOntologyBiologicalProcesslimbic system development

SEMA3A PITX2 LHX5 EMX2 RAX PROP1

9.89e-06141726GO:0021761
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

EPHB2 LHX1 SP100 PHOX2A CDX1 CDX2 OTX2 ALX1 MIXL1 NBEAL2 PITX2 OBSCN NKX3-2 LHX5 SIX1 NOS1 SIX2

1.02e-0514837217GO:0048646
GeneOntologyBiologicalProcesscentral nervous system neuron differentiation

EPHB2 SEMA3A LHX1 PHOX2A LBX1 LHX5 PHOX2B

1.07e-05217727GO:0021953
GeneOntologyBiologicalProcessstem cell differentiation

SEMA3A CDX2 ALX1 SEMA6D PITX2 SIX1 PHOX2B DNMT3L

1.12e-05306728GO:0048863
GeneOntologyBiologicalProcesscerebellar Purkinje cell-granule cell precursor cell signaling

LHX1 LHX5

1.20e-052722GO:0021937
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

HMBOX1 SIN3B SP100 CDX2 NKX6-2 ALX1 PITX2 NKX3-2 ESX1 POU1F1 ZFHX3 SIX1 PROP1 DNMT3L

1.40e-0510537214GO:0000122
GeneOntologyBiologicalProcessear morphogenesis

EPHB2 OTX1 OTX2 NKX3-2 SIX1 SIX2

1.64e-05154726GO:0042471
GeneOntologyBiologicalProcesssomite development

LHX1 CDX1 CDX2 OTX2 SIX1

1.94e-0594725GO:0061053
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

HMBOX1 LHX1 SIN3B SP100 CDX2 NKX6-2 ALX1 PITX2 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 SIX1 PROP1 DNMT3L

2.02e-0513997216GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

HMBOX1 LHX1 SIN3B SP100 CDX2 NKX6-2 ALX1 PITX2 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 SIX1 PROP1 DNMT3L

2.28e-0514137216GO:1902679
GeneOntologyBiologicalProcessadenohypophysis development

PITX2 POU1F1 PROP1

2.68e-0517723GO:0021984
GeneOntologyBiologicalProcessstem cell development

SEMA3A ALX1 SEMA6D PITX2 PHOX2B

2.75e-05101725GO:0048864
GeneOntologyBiologicalProcessautonomic nervous system development

SEMA3A PHOX2A SIX1 PHOX2B

2.78e-0550724GO:0048483
GeneOntologyBiologicalProcessdopaminergic neuron differentiation

PHOX2A OTX2 PITX3 PHOX2B

2.78e-0550724GO:0071542
GeneOntologyBiologicalProcessneural crest cell differentiation

SEMA3A SEMA6D PITX2 SIX1 PHOX2B

3.17e-05104725GO:0014033
GeneOntologyBiologicalProcessganglion development

SEMA3A SIX1 PHOX2B

3.21e-0518723GO:0061548
GeneOntologyBiologicalProcessepithelium development

SEMA3A LHX1 CDX1 CDX2 OTX2 NKX6-2 ALX1 LBX1 PITX2 PITX3 NKX3-2 ASTN2 SIX1 LBX2 POU2F3 SIX2

3.67e-0514697216GO:0060429
GeneOntologyBiologicalProcesspreganglionic parasympathetic fiber development

SEMA3A PHOX2A SIX1

3.80e-0519723GO:0021783
GeneOntologyBiologicalProcessforebrain morphogenesis

OTX1 OTX2 PROP1

3.80e-0519723GO:0048853
GeneOntologyBiologicalProcessnerve development

EPHB2 SEMA3A PHOX2A SIX1 PHOX2B

3.97e-05109725GO:0021675
GeneOntologyBiologicalProcessureter development

LHX1 SIX1 EMX2

4.46e-0520723GO:0072189
GeneOntologyBiologicalProcessneural crest cell migration

SEMA3A SEMA6D PITX2 PHOX2B

6.53e-0562724GO:0001755
GeneOntologyBiologicalProcesscell differentiation in spinal cord

LHX1 PHOX2A LBX1 LHX5

6.96e-0563724GO:0021515
GeneOntologyBiologicalProcessmesenchymal cell migration

SEMA3A SEMA6D PITX2 PHOX2B

7.40e-0564724GO:0090497
GeneOntologyBiologicalProcessmesenchymal cell differentiation

SEMA3A ALX1 SEMA6D PITX2 SIX1 PHOX2B SIX2

7.75e-05296727GO:0048762
GeneOntologyBiologicalProcesssympathetic nervous system development

SEMA3A PHOX2A PHOX2B

7.83e-0524723GO:0048485
GeneOntologyBiologicalProcessregulation of branching involved in ureteric bud morphogenesis

LHX1 SIX1 SIX2

7.83e-0524723GO:0090189
GeneOntologyBiologicalProcessforebrain regionalization

LHX1 OTX2 EMX2

8.88e-0525723GO:0021871
GeneOntologyBiologicalProcessmiddle ear morphogenesis

NKX3-2 SIX1 SIX2

1.00e-0426723GO:0042474
GeneOntologyBiologicalProcessneuron migration

SEMA3A LHX1 PITX2 ASTN2 PHOX2B EMX2

1.14e-04218726GO:0001764
GeneOntologyBiologicalProcesstrigeminal ganglion development

SEMA3A SIX1

1.19e-045722GO:0061551
GeneOntologyBiologicalProcesshindbrain tangential cell migration

EPHB2 PHOX2B

1.19e-045722GO:0021934
GeneOntologyBiologicalProcesssomitogenesis

LHX1 CDX1 CDX2 OTX2

1.45e-0476724GO:0001756
GeneOntologyBiologicalProcessregulation of morphogenesis of an epithelium

LHX1 SIX1 LBX2 SIX2

1.45e-0476724GO:1905330
GeneOntologyBiologicalProcessembryonic skeletal system development

LHX1 ALX1 NKX3-2 SIX1 SIX2

1.69e-04148725GO:0048706
GeneOntologyBiologicalProcesscranial ganglion development

SEMA3A SIX1

1.79e-046722GO:0061550
GeneOntologyBiologicalProcessmuscle structure development

SIN3B LBX1 PITX2 OBSCN EVC ZFHX3 PLEKHM3 SIX1 PHOX2B LBX2 NOS1

1.80e-048587211GO:0061061
GeneOntologyBiologicalProcesscell differentiation in hindbrain

LHX1 LHX5 PHOX2B

1.88e-0432723GO:0021533
GeneOntologyBiologicalProcessdigestive tract development

CDX2 MIXL1 PITX2 NKX3-2 SIX2

1.91e-04152725GO:0048565
GeneOntologyBiologicalProcessmetencephalon development

LHX1 PHOX2A OTX1 OTX2 LHX5

1.97e-04153725GO:0022037
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

EPHB2 SEMA3A NKX6-2 SEMA6D LBX1 MIXL1 PITX3 NKX3-2 ZFHX3 PHOX2B SIX2

2.13e-048757211GO:0045596
GeneOntologyBiologicalProcesspositive regulation of cerebellar granule cell precursor proliferation

LHX1 LHX5

2.50e-047722GO:0021940
GeneOntologyBiologicalProcessneural crest cell migration involved in autonomic nervous system development

SEMA3A PHOX2B

2.50e-047722GO:1901166
GeneOntologyBiologicalProcessregulation of somitogenesis

CDX1 CDX2

2.50e-047722GO:0014807
GeneOntologyBiologicalProcessendocrine system development

NKX6-2 PITX2 POU1F1 SIX1 PROP1

2.50e-04161725GO:0035270
GeneOntologyBiologicalProcessinner ear development

EPHB2 OTX1 OTX2 PI4KB SIX1 PHOX2B

2.55e-04253726GO:0048839
GeneOntologyBiologicalProcesseye development

EPHB2 LHX1 OTX2 PITX2 PITX3 SIX5 RAX CRX

2.63e-04480728GO:0001654
GeneOntologyBiologicalProcessneural crest cell development

SEMA3A SEMA6D PITX2 PHOX2B

2.66e-0489724GO:0014032
GeneOntologyBiologicalProcessvisual system development

EPHB2 LHX1 OTX2 PITX2 PITX3 SIX5 RAX CRX

2.75e-04483728GO:0150063
GeneOntologyBiologicalProcesschordate embryonic development

LHX1 CDX1 CDX2 OTX2 ALX1 TTLL4 PITX2 NKX3-2 ESX1 SIX1 SIX2

2.87e-049067211GO:0043009
GeneOntologyBiologicalProcessembryonic pattern specification

SEMA3A LHX1 OTX2 SIX1

2.90e-0491724GO:0009880
GeneOntologyBiologicalProcessneuron fate commitment

OTX2 NKX6-2 LBX1 SIX1

2.90e-0491724GO:0048663
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

SEMA3A LHX1 ALX1 LBX1 PITX2 ASTN2 SIX1 LBX2 SIX2

2.94e-04619729GO:0002009
GeneOntologyBiologicalProcessdigestive system development

CDX2 MIXL1 PITX2 NKX3-2 SIX2

2.96e-04167725GO:0055123
GeneOntologyBiologicalProcessregulation of kidney development

LHX1 SIX1 SIX2

3.15e-0438723GO:0090183
GeneOntologyBiologicalProcessmesenchyme development

SEMA3A ALX1 SEMA6D PITX2 SIX1 PHOX2B SIX2

3.16e-04372727GO:0060485
GeneOntologyBiologicalProcesspositive regulation of gastrulation

LHX1 OTX2

3.32e-048722GO:2000543
GeneOntologyBiologicalProcessnegative regulation of neurogenesis

EPHB2 SEMA3A NKX6-2 SEMA6D PITX3

3.48e-04173725GO:0050768
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

LHX1 CDX1 CDX2 OTX2 ALX1 TTLL4 PITX2 NKX3-2 ESX1 SIX1 SIX2

3.56e-049297211GO:0009792
GeneOntologyBiologicalProcessmidbrain development

PHOX2A OTX1 OTX2 PITX3

3.70e-0497724GO:0030901
GeneOntologyBiologicalProcessskeletal system morphogenesis

LHX1 CDX1 ALX1 NKX3-2 SIX1 SIX2

4.13e-04277726GO:0048705
GeneOntologyBiologicalProcesspositive regulation of morphogenesis of an epithelium

LHX1 SIX1 LBX2

4.25e-0442723GO:1905332
GeneOntologyBiologicalProcessureter morphogenesis

LHX1 EMX2

4.26e-049722GO:0072197
GeneOntologyBiologicalProcesshypothalamus cell migration

SEMA3A PITX2

4.26e-049722GO:0021855
GeneOntologyBiologicalProcesssympathetic ganglion development

SEMA3A PHOX2B

4.26e-049722GO:0061549
GeneOntologyBiologicalProcessnegative regulation of nervous system development

EPHB2 SEMA3A NKX6-2 SEMA6D PITX3

4.62e-04184725GO:0051961
GeneOntologyBiologicalProcesspituitary gland development

PITX2 POU1F1 PROP1

5.21e-0445723GO:0021983
GeneOntologyBiologicalProcessregulation of cerebellar granule cell precursor proliferation

LHX1 LHX5

5.31e-0410722GO:0021936
GeneOntologyBiologicalProcessembryonic skeletal system morphogenesis

LHX1 ALX1 SIX1 SIX2

5.76e-04109724GO:0048704
GeneOntologyBiologicalProcessnoradrenergic neuron differentiation

PHOX2A PHOX2B

6.48e-0411722GO:0003357
GeneOntologyBiologicalProcessneuron fate determination

OTX2 LBX1

6.48e-0411722GO:0048664
GeneOntologyBiologicalProcessmesendoderm development

LHX1 OTX2

6.48e-0411722GO:0048382
GeneOntologyCellularComponentchromatin

HMBOX1 LHX1 SIN3B PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 H1-9P PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 DNMT3L CRX

3.40e-1814807332GO:0000785
GeneOntologyCellularComponenttranscription regulator complex

LHX1 CDX2 OTX2 ALX1 LBX1 PITX2 POU1F1 SIX5 ZFHX3 SIX1 POU2F3 SIX2 PROP1 CRX

1.58e-085967314GO:0005667
HumanPhenoEnlarged vestibular aqueduct

PI4KB SIX5 SIX1

1.84e-059323HP:0011387
HumanPhenoEctopic anterior pituitary gland

OTX2 POU1F1 PROP1

1.84e-059323HP:0012731
HumanPhenoAnterior pituitary agenesis

OTX2 POU1F1 PROP1

2.62e-0510323HP:0010626
HumanPhenoPituitary dwarfism

OTX2 POU1F1 PROP1

2.62e-0510323HP:0000839
HumanPhenoDecreased circulating luteinizing hormone level

SEMA3A OTX2 POU1F1 PROP1

3.58e-0531324HP:0030344
HumanPhenoDecreased circulating follicle stimulating hormone concentration

SEMA3A OTX2 POU1F1 PROP1

4.08e-0532324HP:0030341
HumanPhenoHypoplasia of the cochlea

PI4KB SIX5 SIX1

4.77e-0512323HP:0008586
HumanPhenoDecreased thyroid-stimulating hormone level

OTX2 POU1F1 PROP1

4.77e-0512323HP:0031098
HumanPhenoAplasia/Hypoplasia of the cochlea

PI4KB SIX5 SIX1

6.17e-0513323HP:0011395
HumanPhenoAplasia/Hypoplasia of the inner ear

PI4KB SIX5 SIX1

7.82e-0514323HP:0008774
HumanPhenoDecreased circulating gonadotropin concentration

SEMA3A OTX2 POU1F1 PROP1

8.15e-0538324HP:0030339
HumanPhenoDecreased cervical spine mobility

OTX2 POU1F1 PROP1

9.74e-0515323HP:0004637
HumanPhenoReduced circulating growth hormone concentration

OTX2 POU1F1 PROP1

9.74e-0515323HP:0034323
HumanPhenoAbnormal lateral semicircular canal morphology

SIX5 SIX1

1.14e-043322HP:0040106
HumanPhenoAbnormal thyroid-stimulating hormone level

OTX2 POU1F1 SMC5 PROP1

1.89e-0447324HP:0031097
HumanPhenoEnlarged cochlear aqueduct

SIX5 SIX1

2.28e-044322HP:0011388
HumanPhenoSepto-optic dysplasia

OTX2 POU1F1 PROP1

2.39e-0420323HP:0100842
HumanPhenoOsteoporosis of vertebrae

OTX2 POU1F1 PROP1

2.39e-0420323HP:0005625
HumanPhenoEctopic posterior pituitary

OTX2 POU1F1 PROP1

2.77e-0421323HP:0011755
HumanPhenoLocalized osteoporosis

OTX2 POU1F1 PROP1

3.20e-0422323HP:0040161
HumanPhenoBranchial sinus

SIX5 SIX1

3.78e-045322HP:0100272
HumanPhenoPosterior pituitary dysgenesis

OTX2 POU1F1 PROP1

4.17e-0424323HP:0011753
HumanPhenoDilatation of renal calices

SIX5 SIX1

5.65e-046322HP:0100581
HumanPhenoAbnormal renal calyx morphology

SIX5 SIX1

5.65e-046322HP:0011130
HumanPhenoGustatory lacrimation

SIX5 SIX1

5.65e-046322HP:0100274
HumanPhenoBranchial cyst

SIX5 SIX1

5.65e-046322HP:0009796
HumanPhenoEuthyroid goiter

SIX5 SIX1

5.65e-046322HP:0009798
HumanPhenoGanglioneuroblastoma

LBX1 PHOX2B

7.87e-047322HP:0006747
HumanPhenoDecreased circulating ACTH concentration

OTX2 POU1F1 PROP1

8.15e-0430323HP:0002920
HumanPhenoAbnormal prolactin level

OTX2 POU1F1 PROP1

8.15e-0430323HP:0040086
MousePhenoperinatal lethality, complete penetrance

LHX1 SIN3B OTX1 OTX2 ALX1 ZFHX4 LBX1 PITX2 NKX3-2 EVC SIX1 PHOX2B EMX2 SIX2

5.50e-077125614MP:0011089
MousePhenoabnormal nervous system development

EPHB2 SEMA3A LHX1 MMP24 PHOX2A OTX1 OTX2 ALX1 LBX1 PITX2 POU1F1 LHX5 SIX1 PHOX2B EMX2 NOS1 RAX DNMT3L

1.01e-0612575618MP:0003861
MousePhenosmall adenohypophysis

PITX2 POU1F1 SIX1 PROP1

1.93e-0623564MP:0008321
MousePhenoabnormal craniofacial bone morphology

CDX1 OTX1 OTX2 ALX1 ZFHX4 PITX2 NKX3-2 EVC POU1F1 LHX5 SIX1 EMX2 PNISR SIX2

3.25e-068275614MP:0002116
MousePhenodecreased thyrotroph cell number

PITX2 POU1F1 PROP1

3.36e-068563MP:0008338
MousePhenoadenohypophysis hypoplasia

PITX2 POU1F1 PROP1

3.36e-068563MP:0008365
MousePhenoabnormal head development

LHX1 OTX2 ALX1 MIXL1 SIX1

4.67e-0662565MP:0012176
MousePhenoabnormal parasympathetic ganglion morphology

PHOX2A OTX2 PHOX2B

5.03e-069563MP:0001034
MousePhenoperinatal lethality

LHX1 SIN3B OTX1 OTX2 ALX1 ZFHX4 LBX1 PITX2 NKX3-2 EVC SIX1 PHOX2B EMX2 RAX SIX2 PROP1

5.62e-0611305616MP:0002081
MousePhenodecreased pituitary hormone level

OTX2 PITX2 POU1F1 ZFHX3 NOS1 PROP1

5.70e-06113566MP:0003972
MousePhenoneonatal lethality, complete penetrance

SIN3B OTX1 OTX2 ALX1 ZFHX4 LBX1 PITX2 NKX3-2 PHOX2B EMX2 SIX2

7.13e-065345611MP:0011087
MousePhenoabnormal axial skeleton morphology

SEMA3A HMBOX1 CDX1 OTX1 CDX2 OTX2 ALX1 ZFHX4 LBX1 PITX2 NKX3-2 EVC POU1F1 LHX5 SIX1 EMX2 PNISR SIX2

8.46e-0614585618MP:0002114
MousePhenoabnormal malleus morphology

OTX2 NKX3-2 SIX1 EMX2

9.79e-0634564MP:0000029
MousePhenoabnormal neuron differentiation

EPHB2 SEMA3A MMP24 PHOX2A PITX2 LHX5 PHOX2B NOS1

1.27e-05275568MP:0009937
MousePhenoabnormal parasympathetic system morphology

PHOX2A OTX2 PHOX2B

1.31e-0512563MP:0001033
MousePhenoabnormal cranium morphology

CDX1 OTX1 OTX2 ALX1 ZFHX4 PITX2 NKX3-2 EVC POU1F1 LHX5 SIX1 PNISR SIX2

1.45e-058135613MP:0000438
MousePhenoabnormal thyrotroph morphology

PITX2 POU1F1 PROP1

2.15e-0514563MP:0008326
MousePhenoabsent forebrain

LHX1 OTX2 RAX

2.15e-0514563MP:0012136
MousePhenoabnormal pituitary hormone level

OTX2 PITX2 POU1F1 SIX5 ZFHX3 NOS1 PROP1

2.19e-05214567MP:0003965
MousePhenoabnormal diencephalon morphology

OTX1 OTX2 PITX2 POU1F1 SIX1 EMX2 RAX PROP1

2.27e-05298568MP:0000830
MousePhenolethality during fetal growth through weaning, complete penetrance

LHX1 SIN3B PHOX2A OTX1 OTX2 ALX1 ZFHX4 LBX1 PITX2 NKX3-2 EVC LHX5 SIX1 PHOX2B EMX2 SIX2

2.43e-0512695616MP:0011111
MousePhenoabnormal breathing pattern

PHOX2A ZFHX4 PITX3 NKX3-2 SIX1 PHOX2B NOS1 PROP1

2.55e-05303568MP:0001951
MousePhenocyanosis

PHOX2A ALX1 ZFHX4 PITX2 LHX5 PHOX2B PROP1

3.11e-05226567MP:0001575
MousePhenoabnormal brainstem morphology

LHX1 PHOX2A OTX1 OTX2 PITX3 PHOX2B RAX

3.20e-05227567MP:0005277
MousePhenoabnormal adenohypophysis morphology

OTX2 PITX2 POU1F1 SIX1 PROP1

3.24e-0592565MP:0004163
MousePhenoabnormal cranial nerve morphology

SEMA3A PHOX2A OTX2 NKX6-2 PITX2 SIX1 PHOX2B RAX

3.30e-05314568MP:0001056
MousePhenoabnormal somatic nervous system morphology

EPHB2 SEMA3A PHOX2A OTX2 NKX6-2 LBX1 PITX2 STK38 POU1F1 SIX1 PHOX2B EMX2 RAX CRX

3.74e-0510255614MP:0002752
MousePhenoabnormal ciliary ganglion morphology

OTX2 PHOX2B

4.72e-053562MP:0004990
MousePhenoabsent prechordal mesoderm

LHX1 OTX2

4.72e-053562MP:0012276
MousePhenoabnormal prechordal mesoderm morphology

LHX1 OTX2

4.72e-053562MP:0012275
MousePhenoabsent middle ear ossicles

NKX3-2 SIX1 EMX2

4.76e-0518563MP:0000040
MousePhenoabnormal cartilage morphology

OTX1 OTX2 ALX1 ZFHX4 PITX2 NKX3-2 EVC SIX1

5.33e-05336568MP:0000163
MousePhenoabnormal cell differentiation

EPHB2 SEMA3A MMP24 SIN3B PHOX2A NBEAL2 PITX2 LHX5 PHOX2B POU2F3 NOS1 DNMT3L

5.79e-057955612MP:0005076
MousePhenoabnormal mouth morphology

OTX2 ALX1 ZFHX4 PITX2 EVC POU1F1 LHX5 SIX1 POU2F3 RAX SIX2

5.85e-056705611MP:0000452
MousePhenoneonatal lethality

SIN3B OTX1 OTX2 ALX1 ZFHX4 LBX1 PITX2 NKX3-2 PHOX2B EMX2 SIX2 PROP1

6.08e-057995612MP:0002058
MousePhenoabnormal forebrain morphology

SEMA3A LHX1 OTX1 OTX2 ALX1 PITX2 PITX3 POU1F1 LHX5 DGCR8 SIX1 EMX2 RAX PROP1

6.12e-0510725614MP:0000783
MousePhenoabnormal craniofacial morphology

CDX1 OTX1 OTX2 ALX1 ZFHX4 PITX2 NKX3-2 EVC POU1F1 LHX5 SIX1 EMX2 PNISR POU2F3 RAX SIX2

6.33e-0513725616MP:0000428
MousePhenocraniofacial phenotype

CDX1 OTX1 OTX2 ALX1 ZFHX4 PITX2 NKX3-2 EVC POU1F1 LHX5 SIX1 EMX2 PNISR POU2F3 RAX SIX2

6.33e-0513725616MP:0005382
MousePhenoabnormal lacrimal gland morphology

OTX1 PITX3 SIX1

6.61e-0520563MP:0001346
MousePhenoabnormal tidal volume

PHOX2A PITX3 NOS1

6.61e-0520563MP:0002313
MousePhenoabnormal lung volume

PHOX2A PITX3 PHOX2B NOS1

6.77e-0555564MP:0001942
MousePhenoabnormal oxygen level

PHOX2A ALX1 ZFHX4 PITX2 LHX5 PHOX2B PROP1

6.86e-05256567MP:0001574
MousePhenoabnormal rib morphology

SEMA3A CDX1 CDX2 PITX2 NKX3-2 EVC SIX1

7.03e-05257567MP:0000150
MousePhenoabnormal middle ear ossicle morphology

OTX2 NKX3-2 SIX1 EMX2

7.27e-0556564MP:0005105
MousePhenoabnormal neuron number

PHOX2A OTX2 LBX1 PITX3 POU1F1 SIX1 PHOX2B EMX2 CRX

7.49e-05456569MP:0008946
MousePhenoabnormal axial mesoderm morphology

LHX1 OTX2 PITX2

7.70e-0521563MP:0001684
MousePhenodecreased somatotroph cell number

PITX2 POU1F1 PROP1

7.70e-0521563MP:0008329
MousePhenoabnormal circulating gonadotropin level

OTX2 POU1F1 SIX5 NOS1 PROP1

8.33e-05112565MP:0003361
MousePhenoabnormal lacrimal apparatus morphology

OTX1 PITX3 SIX1

8.88e-0522563MP:0008968
MousePhenoabnormal neurocranium morphology

CDX1 OTX1 OTX2 ALX1 NKX3-2 EVC SIX1

9.37e-05269567MP:0000074
MousePhenoacephaly

LHX1 OTX2

9.41e-054562MP:0009579
MousePhenoshort zygomatic bone

ALX1 SIX1

9.41e-054562MP:0003108
MousePhenoabsent choroid plexus

OTX2 LHX5

9.41e-054562MP:0008934
MousePhenoabnormal ventral tubercle of atlas morphology

CDX1 NKX3-2

9.41e-054562MP:0004658
MousePhenodecreased circulating gonadotropin level

OTX2 POU1F1 NOS1 PROP1

9.53e-0560564MP:0003363
MousePhenodecreased midbrain size

OTX1 OTX2 RAX

1.02e-0423563MP:0012089
MousePhenoabnormal eye development

HMBOX1 FAM120B OTX2 ALX1 PITX2 PITX3 RAX DNMT3L CRX

1.14e-04482569MP:0001286
MousePhenoabnormal cervical vertebrae morphology

SEMA3A CDX1 CDX2 NKX3-2 SIX1

1.15e-04120565MP:0003048
MousePhenoabnormal incus morphology

OTX2 SIX1 EMX2

1.16e-0424563MP:0005106
MousePhenoabnormal somatotroph morphology

PITX2 POU1F1 PROP1

1.16e-0424563MP:0008322
MousePhenoabnormal luteinizing hormone level

OTX2 PITX2 NOS1 PROP1

1.23e-0464564MP:0003969
MousePhenoabnormal basicranium morphology

CDX1 OTX2 NKX3-2 EVC SIX1

1.30e-04123565MP:0010029
MousePhenoabnormal ocular surface morphology

OTX1 PITX2 PITX3 SIX1

1.47e-0467564MP:0013754
MousePhenoabnormal pituitary gland physiology

OTX1 POU1F1 PROP1

1.48e-0426563MP:0005646
MousePhenoabsent dentate gyrus

LHX5 EMX2

1.56e-045562MP:0000814
MousePhenoabnormal external nares morphology

ALX1 SIX1

1.56e-045562MP:0002235
MousePhenoabnormal bone ossification

SIN3B ZFHX4 DHX40 TTLL4 NKX3-2 EVC SIX1 SIX2

1.64e-04395568MP:0008271
MousePhenoabnormal respiratory function

PHOX2A ZFHX4 PITX3 NKX3-2 SIX1 PHOX2B NOS1 PROP1

1.76e-04399568MP:0002327
MousePhenoincreased neuron number

PHOX2A PITX3 SIX1 EMX2

1.94e-0472564MP:0008947
MousePhenoabnormal pituitary gland morphology

OTX2 PITX2 POU1F1 SIX1 PROP1

2.01e-04135565MP:0000633
MousePhenoabnormal supraoccipital bone morphology

CDX1 ALX1 NKX3-2

2.07e-0429563MP:0000078
MousePhenoabnormal neuroendocrine gland physiology

OTX1 POU1F1 PROP1

2.07e-0429563MP:0013570
MousePhenosmall temporal bone squamous part

ALX1 SIX1

2.34e-046562MP:0030121
MousePhenoabsent incus

SIX1 EMX2

2.34e-046562MP:0004318
MousePhenoabnormal extraocular muscle morphology

OTX2 PITX2

2.34e-046562MP:0005247
MousePhenoabsent midbrain

LHX1 OTX2

2.34e-046562MP:0012087
MousePhenoabsent vomeronasal organ

OTX2 SIX1

2.34e-046562MP:0013595
MousePhenoabnormal midbrain size

OTX1 OTX2 RAX

2.53e-0431563MP:0012088
MousePhenodecreased luteinizing hormone level

OTX2 PITX2 PROP1

2.78e-0432563MP:0005132
MousePhenoabnormal eye distance/ position

OTX2 PITX2 PITX3 SNRNP200

2.91e-0480564MP:0001299
MousePhenoabnormal facial nerve morphology

PHOX2A SIX1 PHOX2B

3.05e-0433563MP:0001071
MousePhenoabnormal anterior head development

LHX1 OTX2

3.27e-047562MP:0030324
MousePhenoabnormal trigeminal V mesencephalic nucleus morphology

OTX1 OTX2

3.27e-047562MP:0000906
MousePhenoabnormal locus ceruleus morphology

PHOX2A PHOX2B

3.27e-047562MP:0003661
MousePhenoabnormal basioccipital bone morphology

CDX1 NKX3-2 EVC

3.34e-0434563MP:0000079
MousePhenoabnormal midbrain morphology

LHX1 OTX1 OTX2 PITX3 RAX

3.37e-04151565MP:0000897
MousePhenodecreased growth hormone level

POU1F1 ZFHX3 PROP1

3.64e-0435563MP:0005136
MousePhenoabnormal head morphology

LHX1 OTX2 ALX1 ZFHX4 MIXL1 PITX2 EVC POU1F1 LHX5 SIX1 POU2F3 RAX SIX2

3.82e-0411205613MP:0000432
MousePhenoabnormal dentate gyrus morphology

POU1F1 LHX5 DGCR8 EMX2

3.84e-0486564MP:0000812
MousePhenoabnormal uvea morphology

OTX1 OTX2 PITX2 PITX3 PHOX2B NOS1

3.90e-04241566MP:0005197
MousePhenoabnormal neuroendocrine gland morphology

OTX2 PITX2 POU1F1 SIX1 PROP1

3.92e-04156565MP:0000631
MousePhenoabnormal somatic sensory system morphology

EPHB2 SEMA3A PHOX2A OTX2 STK38 POU1F1 SIX1 PHOX2B EMX2 CRX

4.18e-047025610MP:0000959
MousePhenopituitary gland hypoplasia

PITX2 PROP1

4.35e-048562MP:0002659
MousePhenoabnormal orbitosphenoid bone morphology

OTX1 OTX2

4.35e-048562MP:0004457
MousePhenosmall zygomatic bone

ALX1 SIX1

4.35e-048562MP:0004468
MousePhenoabsent metanephros

LHX1 SIX1

4.35e-048562MP:0011366
MousePhenodecreased circulating pituitary hormone level

OTX2 POU1F1 NOS1 PROP1

4.38e-0489564MP:0005118
MousePhenoabnormal follicle stimulating hormone level

PITX2 SIX5 NOS1 PROP1

4.38e-0489564MP:0003967
MousePhenoabnormal autonomic nervous system morphology

SEMA3A PHOX2A OTX2 PHOX2B

4.38e-0489564MP:0002751
MousePhenoabnormal thoracic cage morphology

SEMA3A HMBOX1 CDX1 CDX2 PITX2 NKX3-2 EVC SIX1

4.79e-04463568MP:0004624
DomainHomeobox

HMBOX1 LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

5.05e-372347129PF00046
DomainHOMEOBOX_1

HMBOX1 LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

6.54e-372367129PS00027
DomainHOX

HMBOX1 LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

7.43e-372377129SM00389
DomainHOMEOBOX_2

HMBOX1 LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

9.59e-372397129PS50071
DomainHomeobox_dom

HMBOX1 LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

9.59e-372397129IPR001356
DomainHomeobox_CS

LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 POU2F3 RAX SIX2 PROP1 CRX

2.56e-361867127IPR017970
Domain-

HMBOX1 LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

1.56e-3428371291.10.10.60
DomainHomeodomain-like

HMBOX1 LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 SEMA6D ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

4.15e-343327130IPR009057
DomainHTH_motif

LHX1 PHOX2A CDX1 CDX2 NKX6-2 LBX1 NKX3-2 LHX5 SIX1 EMX2 SIX2 PROP1

2.55e-17697112IPR000047
DomainOtx_TF_C

OTX1 OTX2 CRX

5.26e-083713IPR013851
DomainTF_Otx

OTX1 OTX2 CRX

5.26e-083713PF03529
DomainOAR

ALX1 PITX2 PITX3 RAX

2.54e-0715714PF03826
DomainOAR

ALX1 PITX2 PITX3 RAX

3.37e-0716714PS50803
DomainOAR_dom

ALX1 PITX2 PITX3 RAX

3.37e-0716714IPR003654
DomainSIX1_SD

SIX5 SIX1 SIX2

1.82e-067713PF16878
DomainSIX1_SD

SIX5 SIX1 SIX2

1.82e-067713IPR031701
DomainOtx_TF

OTX1 OTX2

1.42e-052712IPR003025
DomainHomeobox_metazoa

CDX1 CDX2 NKX6-2 NKX3-2 EMX2

2.35e-0590715IPR020479
DomainPOU

ESX1 POU1F1 POU2F3

3.45e-0517713IPR013847
DomainHomeobox_Pitx/unc30

PITX2 PITX3

4.26e-053712IPR016233
DomainCaudal_act

CDX1 CDX2

4.26e-053712PF04731
DomainCaudal_activation_dom

CDX1 CDX2

4.26e-053712IPR006820
Domain-

HMBOX1 POU1F1 POU2F3

1.44e-04277131.10.260.40
DomainLambda_DNA-bd_dom

HMBOX1 POU1F1 POU2F3

1.79e-0429713IPR010982
DomainPOU

POU1F1 POU2F3

1.65e-0316712SM00352
DomainPOU_2

POU1F1 POU2F3

1.65e-0316712PS00465
DomainPOU_dom

POU1F1 POU2F3

1.65e-0316712IPR000327
DomainPOU_3

POU1F1 POU2F3

1.65e-0316712PS51179
DomainPou

POU1F1 POU2F3

1.65e-0316712PF00157
DomainPOU_1

POU1F1 POU2F3

1.65e-0316712PS00035
DomainSemaphorin

SEMA3A SEMA6D

2.59e-0320712IPR027231
DomainZnF_U1

ZFHX4 ZFHX3

5.41e-0329712SM00451
DomainZnf_U1

ZFHX4 ZFHX3

5.41e-0329712IPR003604
DomainSema

SEMA3A SEMA6D

6.17e-0331712SM00630
DomainSemap_dom

SEMA3A SEMA6D

6.17e-0331712IPR001627
DomainSema

SEMA3A SEMA6D

6.17e-0331712PF01403
DomainSEMA

SEMA3A SEMA6D

6.17e-0331712PS51004
PathwayREACTOME_KIDNEY_DEVELOPMENT

LHX1 SIX1 EMX2 SIX2

1.34e-0546454M48243
PathwayWP_MARKERS_OF_KIDNEY_CELL_LINEAGE

LHX1 SIX1 EMX2 SIX2

3.63e-0559454M46460
PathwayWP_GENES_CONTROLLING_NEPHROGENESIS

LHX1 SIX1 EMX2

3.67e-0444453M39891
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

HMBOX1 LHX1 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

7.15e-27544742528473536
Pubmed

A census of human transcription factors: function, expression and evolution.

HMBOX1 SP100 PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 LBX1 MIXL1 PITX2 PITX3 NKX3-2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2 PROP1 CRX

8.06e-27908742919274049
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

HMBOX1 LHX1 PHOX2A OTX1 OTX2 NKX6-2 ALX1 ZFHX4 PITX2 ESX1 POU1F1 SIX5 ZFHX3 LHX5 SIX1 LBX2 RAX SIX2

1.81e-22263741820932939
Pubmed

Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2.

LHX1 PHOX2A OTX2 NKX6-2 LBX1 PITX2 LHX5 PHOX2B

6.11e-162774821925604
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

HMBOX1 LHX1 SIN3B PHOX2A OTX1 OTX2 NKX6-2 PITX2 SIX5 ZFHX3 LHX5 SIX1 PHOX2B EMX2 LBX2 POU2F3 RAX SIX2

7.49e-15709741822988430
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

LHX1 OTX1 CDX2 OTX2 NKX6-2 MIXL1 ESX1 FZD10 ZFHX3 LHX5 DGCR8 PHOX2B DNMT3L

5.84e-12424741321731673
Pubmed

Molecular architecture of the developing mouse brain.

EPHB2 NKX6-2 ALX1 FZD10 LHX5 SIX1 PHOX2B EMX2 RAX

1.11e-1113274934321664
Pubmed

Hoxb1 controls anteroposterior identity of vestibular projection neurons.

LHX1 PHOX2A LBX1 LHX5 PHOX2B

1.74e-111174522485187
Pubmed

A genomic atlas of mouse hypothalamic development.

EPHB2 LHX1 OTX2 NKX6-2 SEMA6D PITX2 LHX5 EMX2 NOS1 RAX

2.10e-11205741020436479
Pubmed

Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches.

OTX2 POU1F1 EMX2 RAX PROP1

1.63e-101674519121383
Pubmed

Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.

SEMA3A LHX1 PHOX2A OTX1 OTX2 NKX6-2 ZFHX3 EMX2

3.76e-1013074819386638
Pubmed

Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development.

LHX1 PHOX2A PITX3 LHX5 PHOX2B

2.41e-092674521752929
Pubmed

Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus.

LHX1 PITX2 LHX5 EMX2 RAX

2.96e-092774530063881
Pubmed

LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.

LHX1 OTX2 EMX2 RAX CRX

3.60e-092874523595746
Pubmed

Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium.

LHX1 OTX1 OTX2 LHX5 EMX2

3.60e-092874515917450
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

LHX1 SP100 CDX1 CDX2 OTX2 NKX6-2 MIXL1 PITX2 PITX3 LHX5 SIX1 EMX2 RAX DNMT3L

4.26e-09877741420211142
Pubmed

Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina.

LHX1 OTX1 LHX5 RAX CRX

5.20e-093074521451052
Pubmed

Molecular basis of pituitary dysfunction in mouse and human.

OTX1 PITX2 POU1F1 PROP1

9.22e-091274411420609
Pubmed

Otx5 regulates genes that show circadian expression in the zebrafish pineal complex.

OTX1 OTX2 CRX

9.25e-09374311753388
Pubmed

CRX is a diagnostic marker of retinal and pineal lineage tumors.

OTX1 OTX2 CRX

9.25e-09374319936203
Pubmed

The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities.

PITX2 POU1F1 PROP1

9.25e-0937439685346
Pubmed

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer.

LHX1 OTX2 ZFHX4 ASTN2 ZFHX3 LHX5

1.35e-087574637298722
Pubmed

Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.

SEMA3A LHX1 OTX1 OTX2 NKX6-2 ZFHX3 EMX2

1.56e-0813474719030180
Pubmed

GABAergic and glutamatergic identities of developing midbrain Pitx2 neurons.

LHX1 NKX6-2 PITX2 LHX5

1.86e-081474421246650
Pubmed

Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain.

LHX1 LBX1 LHX5 PHOX2B

2.53e-081574417475798
Pubmed

The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development.

LHX1 PHOX2A LBX1 LHX5

3.37e-081674428603487
Pubmed

Emx and Otx homeobox genes in the developing mouse brain.

OTX1 OTX2 EMX2

3.69e-0847437901323
Pubmed

Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex in the mouse.

OTX1 OTX2 EMX2

3.69e-0847438743751
Pubmed

Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.

DGCR8 SIX1 SIX2

3.69e-08474325670082
Pubmed

Six family genes control the proliferation and differentiation of muscle satellite cells.

SIX5 SIX1 SIX2

3.69e-08474320696153
Pubmed

Nested expression domains of four homeobox genes in developing rostral brain.

OTX1 OTX2 EMX2

3.69e-0847431353865
Pubmed

Conserved homeobox genes in the developing brain.

OTX1 OTX2 EMX2

3.69e-0847437915635
Pubmed

Chromosome locations of human EMX and OTX genes.

OTX1 OTX2 EMX2

3.69e-0847437959790
Pubmed

Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways.

PHOX2A NKX6-2 LBX1 PHOX2B

4.40e-081774422128334
Pubmed

Contribution of Hox genes to the diversity of the hindbrain sensory system.

LHX1 LBX1 LHX5 PHOX2B

4.40e-081774414960494
Pubmed

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.

LBX1 SIX1 LBX2 SIX2

5.65e-081874414628042
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

EPHB2 SEMA3A PHOX2A ALX1 SEMA6D ZFHX4 PHOX2B NOS1

6.58e-0825174829031500
Pubmed

Repression by PRDM13 is critical for generating precision in neuronal identity.

LHX1 PHOX2A LHX5 PHOX2B

8.91e-082074428850031
Pubmed

The murine Fgfrl1 receptor is essential for the development of the metanephric kidney.

LHX1 SIX1 EMX2 SIX2

8.91e-082074419715689
Pubmed

Tissue and developmental distribution of Six family gene products.

SIX5 SIX1 SIX2

9.22e-0857439551859
Pubmed

Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila.

OTX1 OTX2 EMX2

9.22e-0857437913821
Pubmed

Regulation of Otx2 expression and its functions in mouse forebrain and midbrain.

OTX1 OTX2 EMX2

9.22e-08574315201224
Pubmed

Identification and expression of six family genes in mouse retina.

SIX5 SIX1 SIX2

9.22e-0857438814301
Pubmed

Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors.

DGCR8 SIX1 SIX2

9.22e-08574325670083
Pubmed

Expression of murine Lhx5 suggests a role in specifying the forebrain.

LHX1 OTX2 LHX5

9.22e-0857439022063
Pubmed

Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells.

LHX1 OTX2 PITX3 LHX5

1.10e-072174417670789
Pubmed

Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes.

LHX1 LHX5 EMX2 RAX

1.10e-072174429679559
Pubmed

The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei.

LHX1 LBX1 LHX5 PHOX2B

1.34e-072274419088088
Pubmed

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity.

LHX1 NKX6-2 LBX1 LHX5

1.34e-072274412435629
Pubmed

A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors.

LHX1 OTX2 ZFHX4 CRX

1.62e-072374418367606
Pubmed

Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcomes in a Parkinson's disease model.

PHOX2A OTX2 PITX2 PITX3

1.62e-072374435700056
Pubmed

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site.

SIX5 SIX1 SIX2

1.84e-0767439826681
Pubmed

Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system.

OTX1 OTX2 EMX2

1.84e-0767437669695
Pubmed

Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis.

SIX5 SIX1 SIX2

1.84e-07674320074369
Pubmed

The expression profile and clinic significance of the SIX family in non-small cell lung cancer.

SIX5 SIX1 SIX2

1.84e-07674327821176
Pubmed

Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development.

SIX5 SIX1 SIX2

1.84e-07674319900183
Pubmed

Emx2 directs the development of diencephalon in cooperation with Otx2.

LHX1 OTX1 OTX2 EMX2

1.94e-072474411493561
Pubmed

Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization.

LHX1 OTX1 OTX2 EMX2

1.94e-072474420816794
Pubmed

Overlapping functions of SIX homeoproteins during embryonic myogenesis.

PITX2 SIX5 SIX1 SIX2

1.94e-072474437267426
Pubmed

Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border.

PHOX2A OTX1 OTX2 PITX3

2.31e-072574416571633
Pubmed

GDF11 controls the timing of progenitor cell competence in developing retina.

LHX1 OTX2 RAX CRX

2.31e-072574415976303
Pubmed

Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.

OTX1 OTX2 RAX CRX

3.19e-072774424148613
Pubmed

Prrxl1 is required for the generation of a subset of nociceptive glutamatergic superficial spinal dorsal horn neurons.

LHX1 LBX1 LHX5

3.22e-07774320503365
Pubmed

Molecular interaction and synergistic activation of a promoter by Six, Eya, and Dach proteins mediated through CREB binding protein.

SIX5 SIX1 SIX2

3.22e-07774312215533
Pubmed

Role of neuroepithelial Sonic hedgehog in hypothalamic patterning.

LHX1 PITX2 LHX5 EMX2

3.72e-072874419474326
Pubmed

The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.

LHX1 PITX2 POU1F1 ZFHX3

3.72e-072874432868762
Pubmed

Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse.

EPHB2 OTX2 PITX2 RAX

4.96e-073074423426374
Pubmed

Forebrain patterning defects in Small eye mutant mice.

OTX1 OTX2 EMX2

5.14e-0787438951061
Pubmed

Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele.

PITX2 SIX5 SIX1

5.14e-07874330237319
Pubmed

An essential role for RAX homeoprotein and NOTCH-HES signaling in Otx2 expression in embryonic retinal photoreceptor cell fate determination.

OTX2 RAX CRX

5.14e-07874322090505
Pubmed

Impaired interactions between mouse Eyal harboring mutations found in patients with branchio-oto-renal syndrome and Six, Dach, and G proteins.

SIX5 SIX1 SIX2

5.14e-07874311950062
Pubmed

The homeobox gene Hesx1 is required in the anterior neural ectoderm for normal forebrain formation.

LHX1 OTX1 RAX

5.14e-07874310882526
Pubmed

Ectopic HOXA5 expression results in abnormal differentiation, migration and p53-independent cell death of superficial dorsal horn neurons.

LHX1 LBX1 LHX5

5.14e-07874316139370
Pubmed

Hoxa2 downregulates Six2 in the neural crest-derived mesenchyme.

SIX5 SIX1 SIX2

5.14e-07874315634706
Pubmed

Six4, a putative myogenin gene regulator, is not essential for mouse embryonal development.

SIX5 SIX1 SIX2

5.14e-07874311313460
Pubmed

Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.

PHOX2A OTX2 NKX6-2 PITX3

5.69e-073174419592574
Pubmed

Purkinje cells originate from cerebellar ventricular zone progenitors positive for Neph3 and E-cadherin.

LHX1 LBX1 LHX5

7.70e-07974320004188
Pubmed

Pleiotropic effects in Eya3 knockout mice.

SIX5 SIX1 SIX2

7.70e-07974319102749
Pubmed

Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer.

OTX1 OTX2 PITX3

7.70e-07974312764108
Pubmed

Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme.

LHX1 LHX5 SIX1

7.70e-07974316018995
Pubmed

Microphthalmia/Anophthalmia/Coloboma Spectrum – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

OTX2 PITX2 PITX3 RAX

8.34e-073474420301552
Pubmed

Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.

LHX1 OTX1 OTX2 LHX5

1.06e-063674418094027
Pubmed

Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut.

PHOX2A PHOX2B NOS1

1.10e-061074310536054
Pubmed

DRG11 immunohistochemical expression during embryonic development in the mouse.

LHX1 LHX5 PHOX2B

1.10e-061074317676639
Pubmed

Regulation of metanephric kidney development by growth/differentiation factor 11.

LHX1 EMX2 SIX2

1.10e-061074312729564
Pubmed

G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells.

LHX1 OTX2 RAX CRX

1.18e-063774423223288
Pubmed

Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5.

OTX1 LHX5 EMX2

1.51e-061174310325223
Pubmed

Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain.

OTX1 OTX2 EMX2

1.51e-06117439367432
Pubmed

Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm.

LHX1 OTX2 EMX2

1.51e-061174315201223
Pubmed

The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.

LHX1 OTX2 LHX5

1.51e-061174328165338
Pubmed

Natural antisense transcripts associated with genes involved in eye development.

OTX2 RAX CRX

1.51e-061174315703187
Pubmed

Candidate genes for panhypopituitarism identified by gene expression profiling.

OTX2 POU1F1 PROP1

1.51e-061174321828248
Pubmed

Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding.

OTX1 OTX2 PITX2

2.01e-061274323028343
Pubmed

Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation.

PHOX2A NKX6-2 PHOX2B

2.01e-061274316319924
Pubmed

Loss of Ptf1a Leads to a Widespread Cell-Fate Misspecification in the Brainstem, Affecting the Development of Somatosensory and Viscerosensory Nuclei.

LHX1 LHX5 PHOX2B

2.01e-061274326937009
Pubmed

The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord.

LHX1 LBX1 LHX5

2.01e-061274312062039
Pubmed

Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain.

OTX1 OTX2 EMX2

2.01e-06127439486536
Pubmed

Analysis of early ventral telencephalic defects in mice lacking functional Gli3 protein.

LHX1 OTX2 LHX5

2.01e-061274319048639
Pubmed

Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation.

OTX1 OTX2 EMX2

2.01e-06127437588062
Pubmed

A shared transcriptional code orchestrates temporal patterning of the central nervous system.

ZFHX3 LHX5 PHOX2B

2.01e-061274334767545
InteractionALX4 interactions

CDX1 CDX2 OTX2 ALX1 MIXL1 RAX

1.99e-0848736int:ALX4
InteractionLDB1 interactions

LHX1 PITX2 ZFHX3 LHX5 DNMT3L NMD3 CRX

1.96e-07115737int:LDB1
InteractionZFHX4 interactions

LHX1 SP100 ZFHX4 ZFHX3 CRX

6.73e-0673735int:ZFHX4
InteractionM1AP interactions

OTX1 OTX2 CRX

2.99e-0517733int:M1AP
InteractionDLX1 interactions

CDX1 MIXL1 SMC5

3.58e-0518733int:DLX1
InteractionRBM28 interactions

LHX1 CDX1 DHX40 RRP12 STK38 DGCR8 SMC5 CCDC140

5.47e-05368738int:RBM28
InteractionNIPBL interactions

SP100 STK38 SMC5 PNISR SNRNP200 CRX

8.44e-05199736int:NIPBL
CytobandEnsembl 112 genes in cytogenetic band chr10q24

LBX1 RRP12 PITX3 AVPI1

2.56e-04189744chr10q24
GeneFamilyPRD class homeoboxes and pseudogenes

PHOX2A OTX1 OTX2 ALX1 MIXL1 PITX2 PITX3 ESX1 PHOX2B RAX PROP1 CRX

3.22e-17925312521
GeneFamilySINE class homeoboxes

SIX5 SIX1 SIX2

4.73e-076533525
GeneFamilyNKL subclass homeoboxes and pseudogenes

NKX6-2 LBX1 NKX3-2 EMX2 LBX2

1.50e-0667535519
GeneFamilyLIM class homeoboxes

LHX1 LHX5

5.46e-0412532522
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 ZFHX3

8.64e-0415532529
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA3A SEMA6D

1.55e-0320532736
GeneFamilyPOU class homeoboxes and pseudogenes

POU1F1 POU2F3

2.05e-0323532523
GeneFamilyHOXL subclass homeoboxes

CDX1 CDX2

1.02e-0252532518
GeneFamilyFibronectin type III domain containing

EPHB2 OBSCN ASTN2

1.15e-02160533555
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

LHX1 PHOX2A CDX1 CDX2 ALX1 LBX1 MIXL1 PITX2 NKX3-2 ESX1 LHX5 SIX1 LBX2 POU2F3 RAX SIX2

4.56e-172727416M1938
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

LHX1 PHOX2A CDX1 CDX2 ALX1 LBX1 MIXL1 PITX2 NKX3-2 ESX1 LHX5 SIX1 LBX2 POU2F3 RAX SIX2

8.09e-172827416MM822
CoexpressionBENPORATH_SUZ12_TARGETS

PHOX2A OTX1 CDX2 OTX2 NKX6-2 ALX1 SEMA6D LBX1 PITX2 PITX3 NKX3-2 ESX1 SIX5 FZD10 ASTN2 ZFHX3 LHX5 SIX1 PHOX2B EMX2 NOS1 CCDC140 RAX SIX2

4.24e-1610357424M9898
CoexpressionBENPORATH_PRC2_TARGETS

PHOX2A OTX1 CDX2 OTX2 NKX6-2 SEMA6D LBX1 PITX2 PITX3 NKX3-2 ESX1 FZD10 ASTN2 ZFHX3 LHX5 SIX1 PHOX2B CCDC140 RAX SIX2

9.78e-166507420M8448
CoexpressionBENPORATH_EED_TARGETS

PHOX2A OTX1 CDX2 OTX2 NKX6-2 ALX1 SEMA6D LBX1 PITX2 PITX3 NKX3-2 ESX1 SIX5 FZD10 ASTN2 ZFHX3 LHX5 SIX1 PHOX2B EMX2 CCDC140 RAX SIX2

8.10e-1510597423M7617
CoexpressionBENPORATH_ES_WITH_H3K27ME3

PHOX2A CDX1 OTX1 CDX2 OTX2 NKX6-2 SEMA6D LBX1 PITX2 PITX3 NKX3-2 ESX1 FZD10 ASTN2 ZFHX3 LHX5 SIX1 PHOX2B CCDC140 RAX SIX2

2.35e-1211157421M10371
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

MMP24 PHOX2A CDX1 CDX2 NKX6-2 ALX1 LBX1 LHX5 PHOX2B LBX2 POU2F3 RAX

9.50e-085917412M2019
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

MMP24 PHOX2A CDX1 CDX2 NKX6-2 ALX1 LBX1 LHX5 PHOX2B LBX2 POU2F3 RAX

1.14e-076017412MM866
CoexpressionMEISSNER_NPC_HCP_WITH_H3K27ME3

CDX2 ALX1 MIXL1 LHX5 POU2F3

2.99e-0679745M1932
CoexpressionMEISSNER_NPC_HCP_WITH_H3K27ME3

CDX2 ALX1 MIXL1 LHX5 POU2F3

3.19e-0680745MM817
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NKX6-2 LBX1 MIXL1 FZD10 LHX5 POU2F3 RAX SIX2 DNMT3L

3.96e-06438749M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NKX6-2 LBX1 MIXL1 FZD10 LHX5 POU2F3 RAX SIX2 DNMT3L

4.11e-06440749MM832
CoexpressionDESCARTES_ORGANOGENESIS_CHONDROCYTES_AND_OSTEOBLASTS

ALX1 ZFHX4 ZFHX3

6.73e-0528743MM3665
CoexpressionDESCARTES_ORGANOGENESIS_INHIBITORY_NEURON_PROGENITORS

LHX1 LBX1 LHX5

7.49e-0529743MM3651
CoexpressionMATZUK_CENTRAL_FOR_FEMALE_FERTILITY

OTX1 POU1F1 PROP1

7.49e-0529743M1820
CoexpressionLEIN_CEREBELLUM_MARKERS

LHX1 MMP24 PDP2 LHX5

9.97e-0585744MM720
CoexpressionLEIN_CEREBELLUM_MARKERS

LHX1 MMP24 PDP2 LHX5

9.97e-0585744M1723
CoexpressionKIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN

CDX1 CDX2 ALX1 PITX3

1.09e-0487744M2109
CoexpressionHEVNER_CORTEX_CAJAL_RETZIUS_CELLS

LHX1 LHX5

2.18e-048742MM394
CoexpressionGSE17721_LPS_VS_CPG_24H_BMDC_UP

RSAD2 PITX3 DGCR8 SIX1 DNMT3L

2.53e-04199745M4010
CoexpressionGSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP

ADAM19 SEMA6D STK38 SUSD3 AVPI1

2.59e-04200745M6477
CoexpressionGSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN

LHX1 ADAM19 PITX2 NKX3-2 SMC5

2.59e-04200745M9554
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_500

ALX1 PITX2 HEMGN ZFHX3 PHOX2B EMX2

5.26e-0789716gudmap_developingGonad_e11.5_ovary + mesonephros_k1_500
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3

PHOX2A OTX1 CDX2 ADAM19 NKX6-2 ALX1 ZFHX4 PITX2 FZD10 ZFHX3 NCKAP5 SIX1 PHOX2B EMX2 CCDC140

2.63e-0610947115ratio_EB_vs_SC_2500_K3
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#1_top-relative-expression-ranked_500

ALX1 ZFHX4 HEMGN ZFHX3 PHOX2B

2.98e-0667715gudmap_developingGonad_e12.5_ovary_k1_500
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500

ALX1 ZFHX4 HJURP PITX2 HEMGN ZFHX3 PHOX2B EMX2 PNISR

1.01e-05417719gudmap_developingGonad_e11.5_ovary + mesonephros_500
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_1000

ALX1 PITX2 HEMGN ZFHX3 PHOX2B EMX2

1.54e-05159716gudmap_developingGonad_e11.5_ovary + mesonephros_k1_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_100

OTX1 OTX2 LHX5 EMX2 RAX

2.03e-0599715PCBC_ECTO_100
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_100

OTX1 OTX2 LHX5 EMX2 RAX

2.03e-0599715PCBC_ECTO_fibroblast_100
CoexpressionAtlasratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_100

OTX1 ZFHX4 LHX5 EMX2 RAX

2.13e-05100715PCBC_ratio_ECTO_vs_SC_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_100

LHX1 OTX1 OTX2 LHX5 EMX2

2.13e-05100715Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_200

SEMA3A ALX1 ZFHX4 PITX2 ZFHX3 SIX1

2.17e-05169716gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#3

CDX2 ZFHX4 PITX2 FZD10 ZFHX3 PHOX2B

6.22e-05204716ratio_EB_vs_SC_500_K3
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500

ALX1 ZFHX4 HJURP HEMGN ZFHX3 PHOX2B EMX2 PNISR

6.52e-05409718gudmap_developingGonad_e12.5_ovary_500
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#1_top-relative-expression-ranked_1000

ALX1 ZFHX4 HEMGN ZFHX3 PHOX2B

7.50e-05130715gudmap_developingGonad_e12.5_ovary_k1_1000
CoexpressionAtlase10.5_RathkePouch_top-relative-expression-ranked_100

PITX2 SIX1 RAX SIX2

7.50e-0567714Facebase_ST1_e10.5_RathkePouch_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_100

ZFHX4 SIX1 PHOX2B

7.82e-0525713DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_500

SEMA3A ZFHX4 SIX1 PHOX2B SIX2

9.61e-05137715gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k2
CoexpressionAtlasskeletal muscle

LBX1 PITX3 OBSCN STYXL2 SIX1 NOS1 SIX2

9.63e-05320717skeletal muscle
CoexpressionAtlasratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#5

ZFHX4 FZD10 LHX5 EMX2 RAX

9.95e-05138715ratio_EB-blastocyst_vs_EB-fibro_2500_K5
CoexpressionAtlase9.5_OlfacPlacod_top-relative-expression-ranked_100

OTX2 PITX2 SIX1 SIX2

1.11e-0474714Facebase_ST1_e9.5_OlfacPlacod_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_100

ALX1 ZFHX4 PITX2 HEMGN

1.36e-0478714gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_200

ALX1 ZFHX4 PITX2 HEMGN ZFHX3

1.82e-04157715gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_200

ZFHX4 HEMGN ZFHX3 PHOX2B PNISR

2.05e-04161715gudmap_developingGonad_e11.5_ovary + mesonephros_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_100

SEMA3A ZFHX4 SIX1 PHOX2B

2.26e-0489714DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_F-vs-M_top280_280

SEMA3A FAM120B TTLL4 PITX2 ZFHX3 SNRNP200

2.34e-04260716gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_250_F-vs-M
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_200

PHOX2A ZFHX4 PITX2 SIX1 PHOX2B

2.43e-04167715gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500

EPHB2 LHX1 OTX1 OTX2 NCKAP5 LHX5 SMC5 EMX2

2.52e-04498718Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500

CPA4 CDX2 ZFHX4 PITX2 FZD10 ZFHX3 SIX1 PHOX2B

2.52e-04498718PCBC_ratio_EB_vs_SC_500
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_200

HEMGN ZFHX3 PHOX2B

2.78e-0438713gudmap_developingGonad_e11.5_ovary + mesonephros_k2_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#2_top-relative-expression-ranked_200

SEMA3A PITX2

3.05e-048712gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k2
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_100

OTX2 LHX5 EMX2 RAX

3.27e-0498714Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_100
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_100

OTX1 OTX2 LHX5 RAX

3.40e-0499714Facebase_RNAseq_e8.5_Floor Plate_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_100

ALX1 ZFHX4 PITX2 ZFHX3

3.40e-0499714Facebase_RNAseq_e10.5_Lateral Nasal Eminence_100
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_100

LHX1 OTX2 MIXL1 PITX2

3.53e-04100714PCBC_DE_100
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_100

LHX1 OTX2 MIXL1 PITX2

3.53e-04100714PCBC_DE_fibroblast_100
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000

LHX1 ALX1 ZFHX4 HJURP PITX2 HEMGN ZFHX3 PHOX2B EMX2 PNISR

3.64e-048157110gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_k-means-cluster#2_top-relative-expression-ranked_200

LHX1 ALX1 SIX2

3.75e-0442713gudmap_kidney_e15.5_Podocyte_MafB_k2_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_500

PHOX2A RSAD2 ZFHX4 PITX2 HEMGN SIX1 PHOX2B

4.12e-04406717gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

EPHB2 LHX1 SP100 OTX1 OTX2 NCKAP5 LHX5 SMC5 EMX2 PNISR DNMT3L

4.18e-049897111Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

OTX1 CDX2 OTX2 NKX6-2 ALX1 ZFHX4 PITX2 FZD10 SIX1 PHOX2B EMX2

4.28e-049927111PCBC_EB_blastocyst_1000
CoexpressionAtlasECTO blastocyst_vs_ECTO cord blood-Confounder_removed-fold2.0_adjp0.05

SEMA3A OTX1 ADAM19 FZD10 LHX5

4.29e-04189715PCBC_ratio_ECTO blastocyst_vs_ECTO cord blood_cfr-2X-p05
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

SEMA3A FAM120B ALX1 ZFHX4 TTLL4 PITX2 ZFHX3 NCKAP5 SIX1 SNRNP200

5.06e-048507110gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#4_top-relative-expression-ranked_1000

SEMA3A ZFHX4 PHOX2B

5.56e-0448713gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500

SEMA3A ALX1 ZFHX4 PITX2 ZFHX3 SIX1 PHOX2B

5.72e-04429717gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlasDevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#5_top-relative-expression-ranked_1000

ALX1 HEMGN SIX1 PHOX2B

5.80e-04114714gudmap_developingKidney_e11.5_metaneph mesench_1000_k5
CoexpressionAtlase11.5_Emin_MedNasl_SingCel_top-relative-expression-ranked_500_2

PITX2 SIX1 RAX SIX2

7.96e-04124714Facebase_ST1_e11.5_Emin_MedNasl_SingCel_500_2
CoexpressionAtlase9.5_MaxilArch_top-relative-expression-ranked_500_2

OTX2 PITX2 SIX1 SMC5 SIX2

8.52e-04220715Facebase_ST1_e9.5_MaxilArch_500_2
CoexpressionAtlase9.5_FaceMesenchy_top-relative-expression-ranked_500_1

OTX2 DHX40 LHX5 SMC5 RAX

9.06e-04223715Facebase_ST1_e9.5_FaceMesenchy_500_1
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000

HJURP STK38 HEMGN EMX2 PNISR

9.43e-04225715gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlasratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3

OTX1 ZFHX4 ZFHX3 LHX5 EMX2 CCDC140 RAX

9.88e-04471717ratio_ECTO_vs_SC_1000_K3
CoexpressionAtlase10.5_RathkePouch_top-relative-expression-ranked_250

PITX2 SIX1 RAX SIX2

1.06e-03134714Facebase_ST1_e10.5_RathkePouch_250
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ALX1 ZFHX4 PITX2 ZFHX3

1.06e-03134714Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K3
CoexpressionAtlase9.5_FaceMesenchy_top-relative-expression-ranked_100

ALX1 SIX1 SIX2

1.07e-0360713Facebase_ST1_e9.5_FaceMesenchy_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

SEMA3A FAM120B ZFHX4 TTLL4 ZFHX3 NCKAP5 SNRNP200

1.08e-03478717gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k5
CoexpressionAtlasratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5

LHX1 OTX1 OTX2 ADAM19 MIXL1 PITX2 RAX

1.10e-03480717ratio_MESO_vs_SC_1000_K5
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#4_top-relative-expression-ranked_1000

HEMGN ZFHX3 EMX2

1.18e-0362713gudmap_developingGonad_e11.5_testes_k4_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500

SP100 ALX1 ZFHX4 PITX2 ZFHX3 SMC5 EMX2

1.27e-03492717Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

CCHCR1 LHX1 SP100 SEMA6D PI4KB DNMT3L

1.27e-03359716Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#3_top-relative-expression-ranked_100

ZFHX4 SIX1

1.28e-0316712gudmap_developingLowerUrinaryTract_e14.5_ urethra_100_k3
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_100

SEMA3A EMX2

1.28e-0316712gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k1_100
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_500

OTX1 OTX2 ZFHX4 LHX5 EMX2 TSGA10IP RAX

1.32e-03495717PCBC_ECTO_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#3_top-relative-expression-ranked_1000

SEMA3A ZFHX4 SIX1 PHOX2B SIX2

1.33e-03243715gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k3
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500

OTX1 OTX2 ZFHX4 LHX5 EMX2 TSGA10IP RAX

1.35e-03497717PCBC_ECTO_fibroblast_500
CoexpressionAtlasEctoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

FAM120B OTX1 ZFHX4 DHX40 PI4KB SIX5 LHX5 EMX2 PNISR RAX

1.36e-039677110PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

ALX1 ZFHX4 HJURP STK38 HEMGN ZFHX3 PHOX2B EMX2 PNISR

1.39e-03804719gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_k-means-cluster#1_top-relative-expression-ranked_200

SEMA3A LHX1

1.45e-0317712gudmap_kidney_e10.5_UretericTip_HoxB7_k1_200
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

MMP24 OTX1 OTX2 ZFHX4 FZD10 LHX5 EMX2 TSGA10IP CCDC140 RAX

1.45e-039767110PCBC_ECTO_blastocyst_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_500

SEMA3A ZFHX4 SIX1

1.47e-0367713DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_500
ToppCellThalamus|World / BrainAtlas - Mouse McCarroll V32

CDX1 OTX2 ZFHX4 CFAP221 FZD10 ZFHX3

4.14e-081167465ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

LHX1 ZFHX4 PITX3 ZFHX3 LHX5

1.40e-0611574518174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDX2 NBEAL2 CFAP221 TTLL4 PITX2

7.96e-06164745d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCellNS-moderate-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HMBOX1 ADAM19 PDP2 ELMO1 CRX

1.15e-05177745de1ffe3df76100d46ca158bdd2fea2ebbd4656b4
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP24 RSAD2 HEMGN RAX

1.29e-05867444d20625cb666cd09509e07e8db527b94b379509a
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6D SUSD3 ZFHX3 PNISR ELMO1

1.84e-05195745a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA3A ZFHX4 PITX2 PITX3 SIX1

1.98e-0519874555e583321f60c95898d93cd0d2615c6692db52ec
ToppCellLA-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

ADAM19 ALX1 HJURP PITX2

3.92e-05114744ca69dddbdc02fa5718c56362649cd4b9b54f94ce
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Ptrf|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX4 EVC EMX2 DNMT3L

7.15e-05133744a1bc34e5dda4ff4716b857931cc196f6770f58f4
ToppCellwk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

OTX1 SIX1 POU2F3 SIX2

1.39e-04158744adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCellEntopeduncular|World / BrainAtlas - Mouse McCarroll V32

LHX1 NKX6-2 PITX2 ZFHX3

1.46e-04160744833763c8608de4ee6003b8fb682aa9c83d7dea9b
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDX1 PITX3 SIX1 POU2F3

1.53e-041627443dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDX1 PITX3 SIX1 POU2F3

1.53e-041627440a7138266054ea5954649c8b61ef93905d56b068
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDX1 PITX3 SIX1 POU2F3

1.53e-0416274425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCell5'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB2 CDX2 PITX2 RAX

1.53e-04162744472194eccc29c905010e2d8faa67c1a07d5e7118
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HMBOX1 SP100 OTX1 SEMA6D

1.72e-04167744774f3264318b002d0df5d06d41d645366038d0bf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX1 PHOX2A LBX1 LHX5

1.88e-0417174499176a932569fa1c7e1c01009684f5a65244b96e
ToppCellMild-CD4+_T_Exhausted|World / Disease group and Cell class

RSAD2 CFAP221 SUSD3 ELMO1

1.93e-04172744efe68d9477aa873b1637ee689f298120303aa322
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Gad2-Th.Crhbp_(Supramammillary_Nucleus_(SuM)_Dopaminergic?,_Th+/Ddc+)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SEMA3A PHOX2A PHOX2B

2.07e-046974357df6acddf5fe7a1d6bc551c3e3de44102f2f1db
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Gad2-Th.Crhbp_(Supramammillary_Nucleus_(SuM)_Dopaminergic?,_Th+/Ddc+)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SEMA3A PHOX2A PHOX2B

2.07e-0469743f9c1b871e594e57f0d6da3754f76ee41189f4633
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Gad2-Th.Crhbp_(Supramammillary_Nucleus_(SuM)_Dopaminergic?,_Th+/Ddc+)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SEMA3A PHOX2A PHOX2B

2.07e-0469743ee2c7b86ef336c7d0c82a8950bf64457f2683732
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LHX1 LHX5 PROP1

2.16e-0470743677deb7c7c100756a4cdc788d61feb45039a9a97
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

OTX1 FZD10 SIX1 SIX2

2.20e-04178744b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

OTX1 FZD10 SIX1 SIX2

2.20e-04178744fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PHOX2A PHOX2B LBX2 DNMT3L

2.24e-04179744af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SEMA3A ZFHX4 PITX2 FZD10

2.34e-041817449b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NKX6-2 SEMA6D ASTN2 NOS1

2.39e-04182744a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP24 PHOX2A PHOX2B NOS1

2.39e-04182744be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A ADAM19 ZSWIM2 ELMO1

2.39e-0418274441b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A ADAM19 ZSWIM2 ELMO1

2.39e-041827445e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3A ADAM19 ZSWIM2 ELMO1

2.39e-04182744b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 OTX1 FZD10 SIX2

2.44e-04183744ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 CFAP221 EVC ASTN2

2.44e-04183744cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellfacs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 OTX1 FZD10 SIX2

2.44e-04183744f6ebfd7f61e912f92bd07313cc213a171747ac03
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

EPHB2 SEMA6D NKX3-2 ZFHX3

2.54e-041857447dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SEMA6D NKX3-2 ZFHX3 NCKAP5

2.54e-041857449f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SEMA6D NKX3-2 ZFHX3 NCKAP5

2.54e-041857441ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP24 HEMGN RAX

2.55e-04747436f222ebf7cb106bbb2ae3fb3cda660dfec3ea5d0
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EPHB2 SEMA6D NKX3-2 ZFHX3

2.65e-041877445258674d0346e5c51a4b965efcdc1790c970845d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SEMA6D NKX3-2 ZFHX3 NCKAP5

2.65e-0418774413731298bc562ec29582f5da1b4c97261284f6f1
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDX1 CDX2 CFAP221 SUSD3

2.65e-041877448e7ac5808bb292101e33d70616ae784b951e4bf0
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SEMA6D ZFHX4 NKX3-2 SIX1

2.70e-04188744116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAM19 SEMA6D NCKAP5 TSGA10IP

2.70e-04188744f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NKX6-2 ZFHX4 NCKAP5 EMX2

2.70e-04188744505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 OTX1 SIX1 SIX2

2.76e-04189744783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA6D ASTN2 NOS1 ELMO1

2.76e-04189744e059be2965cca70ff5576df055d0af1775b76e00
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NKX6-2 ZFHX4 NCKAP5 EMX2

2.76e-04189744784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 CFAP221 EVC ASTN2

2.76e-04189744aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NKX6-2 ZFHX4 ZFHX3 NCKAP5

2.76e-0418974442ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 LHX1 SEMA6D NBEAL2

2.76e-04189744e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP24 PHOX2A PHOX2B NOS1

2.76e-04189744cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 OTX1 SIX1 SIX2

2.76e-0418974488b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 CFAP221 EVC ASTN2

2.76e-041897448977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NKX6-2 ZFHX4 NCKAP5 EMX2

2.76e-0418974437ecbd73408d462b47d7e5611f203143e08a2689
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB2 OTX1 SIX1 SIX2

2.81e-0419074447e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB2 OTX1 SIX1 SIX2

2.81e-04190744261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 CFAP221 EVC ASTN2

2.81e-041907443fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 CFAP221 EVC ASTN2

2.87e-04191744d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellwk_08-11-Epithelial-PNS-KCNIP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MMP24 PHOX2A PHOX2B NOS1

2.93e-0419274453642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EPHB2 ALX1 ZFHX4 PITX2

2.93e-04192744d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MMP24 SEMA6D NBEAL2 NCKAP5

2.93e-041927440444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-myofibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA3A PITX2 PITX3 SIX1

2.99e-0419374402dfd1df1e7fc84bfca2b0c95138b5b4408bb5d1
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ADAM19 OBSCN ASTN2 NCKAP5

3.05e-0419474489812fb164065041357bb37a3c2d87028ec3de4e
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ZFHX4 LBX1 PITX3 SIX1

3.11e-04195744ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB2 CDX1 CDX2 PITX2

3.11e-04195744b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCell15-Trachea-Epithelial-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

PITX2 PITX3 PHOX2B EMX2

3.11e-041957449e9283a397f56732a0a5f2e2527f154d4c2dd56a
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LBX1 PITX2 PITX3 SIX1

3.11e-0419574480b973d2a23ef9b101c90e1635e68c9a3f78f65d
ToppCellEndothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

SEMA3A ADAM19 PITX3 FZD10

3.17e-0419674436f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCellOutlier-Outlier-Outlier-Outlier-32|World / Primary Cells by Cluster

OTX2 ALX1 LHX5 EMX2

3.17e-04196744433ee89d5451d14a42a4c54b85006bd71884486a
ToppCellOutlier-Outlier|World / Primary Cells by Cluster

OTX2 ALX1 LHX5 EMX2

3.17e-04196744c1d0f8e77a75cbd04d1df18ae7162ac463acfc4c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

LHX1 OTX2 ZFHX3 LHX5

3.17e-041967440767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCellNon-neuronal-Dividing-Radial_Glia-early|World / Primary Cells by Cluster

ALX1 HJURP SIX1 SIX2

3.17e-04196744dd3c6ea5e4ebcc27064f16507de6db6dc8f86fa8
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A ADAM19 ZFHX4 ZFHX3

3.17e-04196744b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCellOutlier-Outlier-Outlier-Outlier|World / Primary Cells by Cluster

OTX2 ALX1 LHX5 EMX2

3.17e-041967442a6ee499cbedcc1ffeb94739d3498207661add33
ToppCellOutlier|World / Primary Cells by Cluster

OTX2 ALX1 LHX5 EMX2

3.17e-0419674462f121878334afa43af60cedcb785035d19caff2
ToppCellNon-neuronal-Dividing-Radial_Glia-early-1|World / Primary Cells by Cluster

ALX1 HJURP SIX1 SIX2

3.17e-0419674470fe6a1a6de891832aaa6276c985b326985e14db
ToppCell5'-Adult-Appendix|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3A SP100 PITX2 ELMO1

3.17e-04196744a579211ef14f348d0c5a290553150222dfbf1515
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A ADAM19 ZFHX4 ZFHX3

3.17e-04196744a31e227de2dc077b81881295b012d22fedbd65ed
ToppCellOutlier-Outlier-Outlier|World / Primary Cells by Cluster

OTX2 ALX1 LHX5 EMX2

3.17e-04196744875fc18ca52633f1a53fd17ffeafc59803aec97d
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SP100 RSAD2 ADAM19 SUSD3

3.23e-041977440b4fdf0131dd67a86ee3209fa66db0ca2e01a10e
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MMP24 SEMA6D NBEAL2 NCKAP5

3.23e-0419774469d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SP100 RSAD2 ADAM19 SUSD3

3.23e-04197744b3876076684781fb8384117f2cf367d828985986
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MMP24 SEMA6D NBEAL2 NCKAP5

3.23e-04197744e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCelldistal-Epithelial-Basal-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CPA4 ALX1 PITX2 EMX2

3.23e-0419774475b4292ce2ad7f9c8b6a4781e1cb71f5b18b74e3
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA3A ADAM19 ZFHX4 ELMO1

3.29e-041987449ab0db78394e730f6866b2db80047149024ad5f6
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA3A OTX1 OTX2 ZFHX4

3.29e-0419874458f5b5e756ab4aa7234aa8d95fba564d6e8c22d9
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA3A ADAM19 ZFHX4 ELMO1

3.29e-04198744e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA3A PITX2 PITX3 SIX1

3.35e-04199744e19b296d583f8bad3b66ee998a8153634d6fe09e
ToppCellproximal-Epithelial-Differentiating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA3A VILL SIX1 SIX2

3.35e-04199744c607346f60e5997e757e5a31cab412ab3734377b
ToppCelldistal-Epithelial-Differentiating_Basal-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZFHX4 PITX2 EMX2 SIX2

3.35e-04199744a1b87c74fe3106ff8bf1c6ff4048d0c3d3fee7ba
ToppCellproximal-3-Epithelial-Differentiating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA3A VILL SIX1 SIX2

3.35e-0419974412e07084fc2d5d4c418df564ccc0e132b056e549
ToppCelldistal-Epithelial-Differentiating_Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZFHX4 PITX2 EMX2 SIX2

3.35e-04199744286d52f25120293620bdbfd62b832f08e118adf6
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

CPA4 SEMA3A ZFHX4 SUSD3

3.35e-041997446cfefd81e8a1a883fb4279ac4ab0b298ed2a0817
ToppCellproximal-Epithelial-Differentiating_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA3A VILL SIX1 SIX2

3.35e-0419974496a89a2578fad9a99c52d2cf9e26e06516a96568
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA3A PITX2 PITX3 SIX1

3.35e-04199744801887db51ac5dc5b068808ff75e3a46643398e9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Stem_cells|GW10 / Sample Type, Dataset, Time_group, and Cell type.

OTX1 ZFHX4 HJURP EMX2

3.42e-04200744474e6ab48f199315f3cca86b81fdf54e0461b7b8
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Suprabasal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

OTX1 SIX1 POU2F3 SIX2

3.42e-04200744924eacea513dde8e3bd805a335bc4285647b800d
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

SP100 RSAD2 OBSCN SUSD3

3.42e-04200744d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron|10w / Sample Type, Dataset, Time_group, and Cell type.

LHX1 OTX2 ZFHX4 LHX5

3.42e-04200744f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

OTX1 ZFHX4 DHX40 EMX2

3.42e-04200744c00cc0b91baa37828895d9d6b8acbc6aa503215a
DiseaseCongenital small ears

OTX2 NKX3-2 EVC SIX5 SIX1

5.26e-0841725C0152423
DiseaseCombined pituitary hormone deficiencies, genetic form

OTX2 POU1F1 PROP1

1.39e-075723cv:C4273747
DiseaseAnophthalmia-microphthalmia syndrome

OTX2 PITX2 PITX3 RAX

1.89e-0721724cv:C5680330
DiseasePituitary Hormone Deficiency, Combined, 1

OTX2 POU1F1 PROP1

2.77e-076723C2751608
Diseasepanhypopituitarism (is_implicated_in)

OTX2 POU1F1 PROP1

4.84e-077723DOID:9410 (is_implicated_in)
DiseasePanhypopituitarism

OTX2 PROP1

1.76e-053722C0242343
DiseaseCongenital central hypoventilation

LBX1 PHOX2B

1.76e-053722cv:C1275808
DiseaseIschemic stroke, cardiac embolism

PITX2 ZFHX3

1.76e-053722EFO_1001493, HP_0002140
DiseaseBranchiootorenal Spectrum Disorders

SIX5 SIX1

1.76e-053722cv:CN043574
Diseaseattention deficit hyperactivity disorder

SEMA3A MMP24 SEMA6D CFAP221 ASTN2 ZFHX3 NCKAP5

2.54e-05354727EFO_0003888
Diseasecongenital central hypoventilation syndrome (is_implicated_in)

LBX1 PHOX2B

3.51e-054722DOID:0060731 (is_implicated_in)
DiseaseBranchio-Oto-Renal Syndrome

SIX5 SIX1

3.51e-054722C0265234
DiseaseBranchio-Oculo-Facial Syndrome

SIX5 SIX1

3.51e-054722C0376524
DiseaseBranchiootorenal Syndrome 2

SIX5 SIX1

3.51e-054722C1970479
DiseaseBranchiootorenal Syndrome 1

SIX5 SIX1

3.51e-054722C4551702
DiseaseBilateral Wilms Tumor

DGCR8 SIX1 SIX2

4.86e-0529723C2930471
DiseaseNephroblastoma

DGCR8 SIX1 SIX2

9.39e-0536723C0027708
DiseaseMICROPHTHALMIA, ISOLATED 1

OTX2 RAX

1.22e-047722C1855052
DiseaseMicrophthalmos, Autosomal Recessive

OTX2 RAX

1.22e-047722C4551977
Diseasebranchiootorenal syndrome (implicated_via_orthology)

SIX5 SIX1

1.22e-047722DOID:14702 (implicated_via_orthology)
Diseasefamilial sick sinus syndrome

PITX2 ZFHX3

1.63e-048722MONDO_0012061
DiseaseAnterior segment dysgenesis

PITX2 PITX3

1.63e-048722cv:C1862839
Diseasesick sinus syndrome

PITX2 ZFHX3

1.63e-048722MONDO_0001823
DiseaseDisorder of eye

OTX2 PITX2 PITX3 SNRNP200 CRX

1.73e-04212725C0015397
DiseaseSchizophrenia

PITPNM1 SEMA3A PITX3 ASTN2 DGCR8 PHOX2B EMX2 NOS1 DNMT3L

2.91e-04883729C0036341
Diseasetriacylglycerol 56:2 measurement

ZFHX4 NFILZ

3.18e-0411722EFO_0010429
DiseaseMental Disorders, Severe

DGCR8 NOS1

3.81e-0412722C4046029
DiseaseBehavior Disorders

DGCR8 NOS1

3.81e-0412722C0004930
DiseaseMental disorders

DGCR8 NOS1

3.81e-0412722C0004936
DiseaseDiagnosis, Psychiatric

DGCR8 NOS1

3.81e-0412722C0376338
DiseaseFetal Alcohol Spectrum Disorders

OTX2 NOS1

4.50e-0413722C2985290
DiseaseCraniofacial Abnormalities

ALX1 PITX2 SIX1 RAX

5.85e-04156724C0376634
DiseaseFetal Alcohol Syndrome

OTX2 NOS1

7.80e-0417722C0015923
DiseaseAmphetamine-Related Disorders

CCHCR1 ASTN2 NOS1

8.29e-0475723C0236733
DiseaseAmphetamine Abuse

CCHCR1 ASTN2 NOS1

8.29e-0475723C0236807
DiseaseAmphetamine Addiction

CCHCR1 ASTN2 NOS1

8.29e-0475723C0236804
DiseaseFemale Urogenital Diseases

LHX1 EMX2

8.76e-0418722C1720887
Diseaseactivities of daily living score measurement

FZD10 NOS1

1.20e-0321722EFO_0008451
DiseaseKallmann Syndrome

SEMA3A OTX2

1.84e-0326722C0162809
Diseaseatrial fibrillation

ZFHX4 PITX2 PITX3 ASTN2 ZFHX3

2.15e-03371725EFO_0000275
Disease1,5 anhydroglucitol measurement

PHOX2A NCKAP5

2.28e-0329722EFO_0008009

Protein segments in the cluster

PeptideGeneStartEntry
QNRRAKWRKRERYGQ

ALX1

181

Q15699
RAKWKRNQRVLMLRN

ESX1

191

Q8N693
RQVKIWFQNRRAKER

CDX1

196

P47902
SERQVKIWFQNRRAK

CDX2

226

Q99626
CFRKLNARRRQDKFW

ELMO1

561

Q92556
SGLLQRRRKWRSQLK

DNMT3L

151

Q9UJW3
WALQFTQQTKKRPRR

ADAM19

186

Q9H013
HSRKKSARIRRNWRK

AVPI1

121

Q5T686
KKFRTWAERRQFNRE

DGCR8

456

Q8WYQ5
QPTKRSKRNRWRRQS

CCDC140

51

Q96MF4
RRWQKRRRIPQKSAS

ASTN2

231

O75129
KTFIMQNWNSRRRHR

HJURP

286

Q8NCD3
WEKRRKNNEAAKRSR

NFILZ

46

A0A5F9ZHS7
RRNKRYALTGQKWRQ

MMP24

151

Q9Y5R2
VYNWFANRRKEIKRR

HMBOX1

326

Q6NT76
ESSQNNWLRTKFIRR

EPHB2

66

P29323
VWFQNRRSKERRMKQ

LHX1

226

P48742
VWFQNRRSKERRMKQ

LHX5

226

Q9H2C1
VRRELQKKQKSFWQR

PLEKHM3

726

Q6ZWE6
TWFQNRRAKLKRDVE

LBX2

131

Q6XYB7
RVWFCNRRQKEKRIN

POU2F3

326

Q9UKI9
TWSLRNRELLRKRKA

HEMGN

31

Q9BXL5
RVQVWFKNRRAKCRQ

OTX1

81

P32242
SLISNDRSWKRNKFR

NOS1

961

P29475
KQLKFLLARSRWQRS

OBSCN

6736

Q5VST9
KIWFQNRRYKTKRRQ

NKX3-2

251

P78367
VSNRNKLKWRLFSRV

PDP2

31

Q9P2J9
WQQVCSRRLKKKSRR

FZD10

531

Q9ULW2
TQTQNRLWRKTRSRN

CPA4

231

Q9UI42
FTRKCQSLLNRWREK

CCHCR1

326

Q8TD31
WFQNRRTKFKRQKLE

EMX2

201

Q04743
KSNRFRRQQWKLFQE

EVC

571

P57679
TWFQNRRAKLKRDLE

LBX1

171

P52954
KVKRQRQQRWRSGQR

H1-9P

186

P60008
REDARRRWTNKENVK

DHX40

716

Q8IX18
KNRRAKWRKRERSQQ

PITX3

111

O75364
SRVQVWFKNRRAKCR

CRX

81

O43186
WFKNRRAKCRQQRQQ

CRX

86

O43186
WVKRRLKNNREISRI

FAM120B

101

Q96EK7
RVQVWFKNRRAKCRQ

OTX2

81

P32243
NNTWLSRSRAQKRFQ

CFAP221

451

Q4G0U5
NLRRRQWRKTRAKEL

TSGA10IP

301

Q3SY00
KRRRSNRSAQLWSQL

SUSD3

136

Q96L08
RKAETWKRNRRQLAF

STK38

266

Q15208
RATFWLLATKRRKQQ

RSAD2

36

Q8WXG1
LRKRQSSQNWDKRLS

NCKAP5

361

O14513
FQNRRTKWRKRHAVE

NKX6-2

196

Q9C056
WFCNRRQREKRVKTS

POU1F1

261

P28069
QFARKLWRSSRRISQ

NBEAL2

2726

Q6ZNJ1
SLTQVSNWFKNRRQR

SIX5

241

Q8N196
QRNLKKFRRRWQSEQ

SIN3B

1016

O75182
TQVSNWFKNRRQRDR

SIX1

166

Q15475
WFKNRRQRDRAAEAK

SIX1

171

Q15475
RRAKWRKRERNQQAE

PITX2

136

Q99697
FCEQVWKRDRKQRRQ

SEMA3A

721

Q14563
ARRRRQNNSAKQSWL

PI4KB

116

Q9UBF8
EQRKLARQRSRAWLK

RRP12

1096

Q5JTH9
NRRAKWRRQEKLEVS

RAX

186

Q9Y2V3
REKWQRKRTQVKIRN

PITPNM1

901

O00562
WFRNTLFKERQRNKD

ZFHX4

2131

Q86UP3
QVWFQNRRAKSRRQS

MIXL1

131

Q9H2W2
WRRRQEETRTKLQKR

STYXL2

1141

Q5VZP5
VWFQNRRAKFRKQER

PHOX2A

136

O14813
QKKRWQQRGRKANTR

SP100

566

P23497
WFQNRRAKQRKQERS

PROP1

116

O75360
TQVSNWFKNRRQRDR

SIX2

166

Q9NPC8
WFKNRRQRDRAAEAK

SIX2

171

Q9NPC8
KQLFRTWSEKRRRNQ

VILL

341

O15195
TFTFREKRNQKWRSL

ZSWIM2

271

Q8NEG5
SRRWKQRKNVQNINL

SNRNP200

1436

O75643
RHRIRQKQEAFWRKE

PNISR

416

Q8TF01
NTWNLKAFQRRRRRI

SMC5

1081

Q8IY18
IPNKKLTWRSRQQDR

SEMA6D

91

Q8NFY4
KDRLWRNLSRMQSRF

TTLL4

671

Q14679
RVQVWFQNRRAKFRK

PHOX2B

141

Q99453
HWFRNTLFKERQRNK

ZFHX3

2191

Q15911
KSYDRTKRQRRRNWK

NMD3

406

Q96D46
TKRQRRRNWKLKELA

NMD3

411

Q96D46