Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

RRAS2 DNAH10 ATP8A2 DNAH2 DHX57 RAB40A HELB IQCA1L IQCA1 RAB40AL RAB40B AGAP7P AGAP4 RAB4A AGAP6

2.43e-0477513515GO:0017111
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

2.70e-0441352GO:0005219
GeneOntologyMolecularFunctionaliphatic amine oxidase activity

MAOB AOC2

2.70e-0441352GO:0052595
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PCSK5 MASP1 KLK10 PCSK6 PCSK7 MMP2 MMP13

3.14e-041901357GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

PCSK5 MASP1 KLK10 PCSK6 PCSK7 MMP2 MMP13

5.25e-042071357GO:0008236
GeneOntologyMolecularFunctionpyrophosphatase activity

RRAS2 DNAH10 ATP8A2 DNAH2 DHX57 RAB40A HELB IQCA1L IQCA1 RAB40AL RAB40B AGAP7P AGAP4 RAB4A AGAP6

5.59e-0483913515GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

RRAS2 DNAH10 ATP8A2 DNAH2 DHX57 RAB40A HELB IQCA1L IQCA1 RAB40AL RAB40B AGAP7P AGAP4 RAB4A AGAP6

5.65e-0484013515GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

RRAS2 DNAH10 ATP8A2 DNAH2 DHX57 RAB40A HELB IQCA1L IQCA1 RAB40AL RAB40B AGAP7P AGAP4 RAB4A AGAP6

5.65e-0484013515GO:0016818
GeneOntologyMolecularFunctionserine hydrolase activity

PCSK5 MASP1 KLK10 PCSK6 PCSK7 MMP2 MMP13

6.05e-042121357GO:0017171
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

6.69e-0461352GO:0048763
GeneOntologyCellularComponentaggresome

SFMBT2 SQSTM1 CABIN1 PRDM16

1.16e-04401324GO:0016235
DomainHELP

EML6 EML5 EML1

6.80e-0661323PF03451
DomainHELP

EML6 EML5 EML1

6.80e-0661323IPR005108
DomainP_proprotein

PCSK5 PCSK6 PCSK7

1.18e-0571323PF01483
DomainS8_pro-domain

PCSK5 PCSK6 PCSK7

1.18e-0571323IPR032815
DomainPrprotnconvertsP

PCSK5 PCSK6 PCSK7

1.18e-0571323IPR002884
Domain-

PCSK5 PCSK6 PCSK7

1.18e-05713233.30.70.850
DomainS8_pro-domain

PCSK5 PCSK6 PCSK7

1.18e-0571323PF16470
DomainPeptidase_S8_His-AS

PCSK5 PCSK6 PCSK7

2.81e-0591323IPR022398
DomainPeptidase_S8_Ser-AS

PCSK5 PCSK6 PCSK7

2.81e-0591323IPR023828
DomainPeptidase_S8_subtilisin-rel

PCSK5 PCSK6 PCSK7

3.99e-05101323IPR015500
DomainSUBTILASE_ASP

PCSK5 PCSK6 PCSK7

3.99e-05101323PS00136
DomainSUBTILASE_HIS

PCSK5 PCSK6 PCSK7

3.99e-05101323PS00137
DomainSUBTILASE_SER

PCSK5 PCSK6 PCSK7

3.99e-05101323PS00138
Domain-

PCSK5 PCSK6 PCSK7

5.46e-051113233.40.50.200
DomainPeptidase_S8/S53_dom

PCSK5 PCSK6 PCSK7

5.46e-05111323IPR000209
DomainPeptidase_S8

PCSK5 PCSK6 PCSK7

5.46e-05111323PF00082
DomainOxysterol-bd_CS

OSBPL2 OSBPL3 OSBPL8

7.25e-05121323IPR018494
DomainOxysterol_BP

OSBPL2 OSBPL3 OSBPL8

7.25e-05121323PF01237
DomainOxysterol-bd

OSBPL2 OSBPL3 OSBPL8

7.25e-05121323IPR000648
DomainOSBP

OSBPL2 OSBPL3 OSBPL8

7.25e-05121323PS01013
DomainRyanodine_rcpt

RYR2 RYR3

1.48e-0431322IPR003032
DomainRyanrecept_TM4-6

RYR2 RYR3

1.48e-0431322IPR009460
DomainRyR

RYR2 RYR3

1.48e-0431322PF02026
DomainRR_TM4-6

RYR2 RYR3

1.48e-0431322PF06459
DomainRyan_recept

RYR2 RYR3

1.48e-0431322IPR013333
DomainPropept_inh

PCSK5 PCSK6 PCSK7

2.18e-04171323IPR009020
DomainSOCS

RAB40A RAB40AL RAB40B

3.60e-04201323SM00253
DomainEGF-like_dom

PCSK5 MASP1 ADGRE2 EGFL6 MMRN1 PCSK6 LRP2 NAGPA

3.97e-042491328IPR000742
DomainQuinoprotein_ADH-like_supfam

EMC1 EML6 EML5 EML1

5.34e-04531324IPR011047
DomainRIH_assoc-dom

RYR2 RYR3

7.30e-0461322IPR013662
DomainGF_recep_IV

PCSK5 PCSK6

7.30e-0461322PF14843
DomainGF_recep_IV

PCSK5 PCSK6

7.30e-0461322IPR032778
DomainPeptidase_S8_Asp-AS

PCSK5 PCSK6

7.30e-0461322IPR023827
DomainIns145_P3_rec

RYR2 RYR3

7.30e-0461322PF08709
DomainRIH_assoc

RYR2 RYR3

7.30e-0461322PF08454
DomainRIH_dom

RYR2 RYR3

7.30e-0461322IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

7.30e-0461322IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

7.30e-0461322IPR015925
Domain-

RYR2 RYR3

7.30e-04613221.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

7.30e-0461322PF01365
DomainEGF-type_Asp/Asn_hydroxyl_site

MASP1 ADGRE2 EGFL6 MMRN1 LRP2

9.36e-041061325IPR000152
DomainArfGap

AGAP7P AGAP4 AGAP6

1.10e-03291323SM00105
DomainARFGAP

AGAP7P AGAP4 AGAP6

1.10e-03291323PS50115
DomainArfGap

AGAP7P AGAP4 AGAP6

1.10e-03291323PF01412
DomainArfGAP

AGAP7P AGAP4 AGAP6

1.10e-03291323IPR001164
DomainDWB

SMAD3 SMAD7

1.35e-0381322SM00524
DomainMH2

SMAD3 SMAD7

1.35e-0381322PS51076
DomainMH1

SMAD3 SMAD7

1.35e-0381322PS51075
DomainDHC_N1

DNAH10 DNAH2

1.35e-0381322PF08385
Domain-

SMAD3 SMAD7

1.35e-03813223.90.520.10
DomainMAD_homology_MH1

SMAD3 SMAD7

1.35e-0381322IPR013019
DomainDwarfin

SMAD3 SMAD7

1.35e-0381322IPR013790
DomainMH2

SMAD3 SMAD7

1.35e-0381322PF03166
DomainSMAD_dom_Dwarfin-type

SMAD3 SMAD7

1.35e-0381322IPR001132
DomainDynein_heavy_dom-1

DNAH10 DNAH2

1.35e-0381322IPR013594
DomainEGF

PCSK5 ADGRE2 EGFL6 MMRN1 PCSK6 LRP2 NAGPA

1.42e-032351327SM00181
DomainEGF_CA

MASP1 ADGRE2 EGFL6 MMRN1 LRP2

1.75e-031221325SM00179
DomainRAB

RAB40A RAB40AL RAB40B RAB4A

1.78e-03731324PS51419
DomainEGF-like_Ca-bd_dom

MASP1 ADGRE2 EGFL6 MMRN1 LRP2

1.88e-031241325IPR001881
DomainMIR

RYR2 RYR3

2.15e-03101322PF02815
DomainMIR_motif

RYR2 RYR3

2.15e-03101322IPR016093
DomainMIR

RYR2 RYR3

2.15e-03101322PS50919
DomainMIR

RYR2 RYR3

2.15e-03101322SM00472
DomainIg_I-set

SDK2 CEACAM5 MYOM1 CEACAM1 KIRREL3 SDK1

2.33e-031901326IPR013098
DomainI-set

SDK2 CEACAM5 MYOM1 CEACAM1 KIRREL3 SDK1

2.33e-031901326PF07679
DomainSOCS_box

RAB40A RAB40AL RAB40B

2.43e-03381323PF07525
DomainSOCS_box

RAB40A RAB40AL RAB40B

2.62e-03391323SM00969
DomainSOCS_box

RAB40A RAB40AL RAB40B

2.62e-03391323IPR001496
DomainSOCS

RAB40A RAB40AL RAB40B

2.62e-03391323PS50225
DomainRas

RRAS2 RAB40A RAB40AL RAB40B RAB4A

2.81e-031361325PF00071
DomainMAD_homology1_Dwarfin-type

SMAD3 SMAD7

3.12e-03121322IPR003619
DomainDWA

SMAD3 SMAD7

3.12e-03121322SM00523
DomainMH1

SMAD3 SMAD7

3.12e-03121322PF03165
DomainEGF_CA

MASP1 ADGRE2 EGFL6 LRP2

3.24e-03861324PF07645
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH2

4.27e-03141322IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH2

4.27e-03141322IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH2

4.27e-03141322IPR013602
DomainDHC_N2

DNAH10 DNAH2

4.27e-03141322PF08393
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH2

4.27e-03141322IPR011704
DomainPLAC

PCSK5 PCSK6

4.27e-03141322PF08686
DomainMT

DNAH10 DNAH2

4.27e-03141322PF12777
DomainAAA_8

DNAH10 DNAH2

4.27e-03141322PF12780
DomainCNH

TNIK MAP4K4

4.27e-03141322SM00036
DomainAAA_5

DNAH10 DNAH2

4.27e-03141322PF07728
DomainDHC_fam

DNAH10 DNAH2

4.90e-03151322IPR026983
DomainDynein_heavy

DNAH10 DNAH2

4.90e-03151322PF03028
DomainPept_M10A_Zn_BS

MMP2 MMP13

4.90e-03151322IPR021158
DomainCNH

TNIK MAP4K4

4.90e-03151322PF00780
DomainDynein_heavy_dom

DNAH10 DNAH2

4.90e-03151322IPR004273
DomainCNH

TNIK MAP4K4

4.90e-03151322PS50219
DomainCNH_dom

TNIK MAP4K4

4.90e-03151322IPR001180
DomainEGF_Ca-bd_CS

MASP1 ADGRE2 EGFL6 LRP2

4.98e-03971324IPR018097
DomainGrowth_fac_rcpt_

PCSK5 ADGRE2 EGFL6 PCSK6 LRP2

5.04e-031561325IPR009030
DomainEGF_CA

MASP1 ADGRE2 EGFL6 LRP2

5.35e-03991324PS01187
DomainASX_HYDROXYL

MASP1 ADGRE2 EGFL6 LRP2

5.54e-031001324PS00010
DomainSMAD_dom-like

SMAD3 SMAD7

5.58e-03161322IPR017855
Domain-

SMAD3 SMAD7

5.58e-031613222.60.200.10
DomainSmall_GTPase

RRAS2 RAB40A RAB40AL RAB40B RAB4A

5.60e-031601325IPR001806
DomainWD40_repeat_CS

EML6 COP1 EML5 RACK1 STRAP

6.21e-031641325IPR019775
DomainHemopexin_CS

MMP2 MMP13

6.29e-03171322IPR018486
Pubmed

Maturation of HIV envelope glycoprotein precursors by cellular endoproteases.

PCSK5 PCSK6 PCSK7

5.72e-083135311063880
Pubmed

Retroviral envelope glycoprotein processing: structural investigation of the cleavage site.

PCSK5 PCSK6 PCSK7

2.28e-07413539521771
Pubmed

OSBP-related proteins (ORPs) in human adipose depots and cultured adipocytes: evidence for impacts on the adipocyte phenotype.

OSBPL2 OSBPL3 OSBPL8

5.69e-075135323028956
Pubmed

Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates.

PCSK5 PCSK6 PCSK7

5.69e-075135311380615
Pubmed

Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.

PCSK5 PCSK6 PCSK7

5.69e-075135318664504
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40A RAB40AL RAB40B

5.69e-075135327909076
Pubmed

PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.

PRDM16 SMAD3 SMAD7

1.13e-066135317467076
Pubmed

Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines.

PCSK5 PCSK6 PCSK7

1.13e-06613538940009
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DGCR2 SDK2 EMC1 XPO4 SLC7A6 IVNS1ABP KCTD5 ZNF516 AGAP7P MAP4K4 AGAP4 AGAP6

1.15e-065291351214621295
Pubmed

Proteolytic processing in the secretory pathway.

PCSK5 PCSK6 PCSK7

1.98e-067135310409610
Pubmed

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.

PCSK5 PCSK6 PCSK7

1.98e-06713537819324
Pubmed

STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling.

STRAP SMAD3 SMAD7

1.98e-067135310757800
Pubmed

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

PCSK5 PCSK6 PCSK7

3.16e-06813539885250
Pubmed

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

OSBPL2 OSBPL3 OSBPL8

3.16e-068135317428193
Pubmed

Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals.

PCSK5 PCSK6 PCSK7

3.16e-068135310037747
Pubmed

The activation and physiological functions of the proprotein convertases.

PCSK5 PCSK6 PCSK7

4.72e-069135318343183
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP7P AGAP4 AGAP6

4.72e-069135312640130
Pubmed

The biology and therapeutic targeting of the proprotein convertases.

PCSK5 PCSK6 PCSK7

4.72e-069135322679642
Pubmed

The prohormone theory and the proprotein convertases: it is all about serendipity.

PCSK5 PCSK6 PCSK7

4.72e-069135321805236
Pubmed

The proprotein convertases, 20 years later.

PCSK5 PCSK6 PCSK7

4.72e-069135321805237
Pubmed

The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions.

PCSK5 PCSK6 PCSK7

4.72e-069135323775089
Pubmed

SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

PCSK5 PCSK6 PCSK7

4.72e-06913538698813
Pubmed

Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.

PCSK5 PCSK6 PCSK7

6.73e-0610135316163737
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP7P AGAP4 AGAP6

6.73e-0610135320664521
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

ASNSD1 EPPK1 CEACAM5 NUP210L SYNE1 DNAH2 HEATR1 IVNS1ABP RACK1 ODR4 EML1 TMCO3 DMBT1

8.17e-067541351335906200
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP7P AGAP4 AGAP6

9.22e-0611135315381706
Pubmed

The OSBP-related protein family in humans.

OSBPL2 OSBPL3 OSBPL8

9.22e-0611135311483621
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL2 OSBPL3 OSBPL8

1.23e-0512135311735225
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL2 OSBPL3 OSBPL8

1.23e-0512135312215260
Pubmed

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans.

RAPGEF4 PLCE1

1.50e-052135221478675
Pubmed

A novel contiguous deletion involving NDP, MAOB and EFHC2 gene in a patient with familial Norrie disease: bilateral blindness and leucocoria without other deficits.

MAOB EFHC2

1.50e-052135229321361
Pubmed

Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors.

CEACAM5 CEACAM1

1.50e-052135233522633
Pubmed

MMP-2 and MMP-13 affect vasculogenic mimicry formation in large cell lung cancer.

MMP2 MMP13

1.50e-052135228766880
Pubmed

Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways.

MMP13 SMAD3

1.50e-052135212270924
Pubmed

Complement factor I upregulates expression of matrix metalloproteinase-13 and -2 and promotes invasion of cutaneous squamous carcinoma cells.

MMP2 MMP13

1.50e-052135233813765
Pubmed

Protein expression of carcinoembryonic antigen cell adhesion molecules in benign and malignant melanocytic skin lesions.

CEACAM5 CEACAM1

1.50e-052135219461083
Pubmed

[SMAD3 inhibits the expression of MMP-2 in mouse embryonic fibroblasts].

MMP2 SMAD3

1.50e-052135216018191
Pubmed

Sidekick-1 is upregulated in glomeruli in HIV-associated nephropathy.

SDK2 SDK1

1.50e-052135215213259
Pubmed

[Silencing of SMAD family member 3 promotes M2 polarization of macrophages and the expression of SMAD7 in rheumatoid arthritis].

SMAD3 SMAD7

1.50e-052135237882714
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

1.50e-05213528898078
Pubmed

Definition of the critical domains required for homophilic targeting of mouse sidekick molecules.

SDK2 SDK1

1.50e-052135215703275
Pubmed

Architecture of cell-cell adhesion mediated by sidekicks.

SDK2 SDK1

1.50e-052135230150416
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

1.50e-052135214550562
Pubmed

High expression levels of SMAD3 and SMAD7 at diagnosis predict poor prognosis in acute myeloid leukemia patients undergoing chemotherapy.

SMAD3 SMAD7

1.50e-052135230177817
Pubmed

Expression of CEACAM1 or CEACAM5 in AZ-521 cells restores the type IV secretion deficiency for translocation of CagA by Helicobacter pylori.

CEACAM5 CEACAM1

1.50e-052135230321907
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

1.50e-052135221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

1.50e-052135216678258
Pubmed

Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases.

PCSK5 PCSK6

1.50e-052135218061232
Pubmed

Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract.

CEACAM5 CEACAM1

1.50e-052135229760215
Pubmed

SETDB1 regulates SMAD7 expression for breast cancer metastasis.

SETDB1 SMAD7

1.50e-052135230545440
Pubmed

Structure and in vitro transcription of the rat CYP2A1 and CYP2A2 genes and regional localization of the CYP2A gene subfamily on mouse chromosome 7.

GPI FES

1.50e-05213522322568
Pubmed

Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease.

PCSK5 PCSK6

1.50e-05213528335106
Pubmed

The relationship of metalloproteinase gene polymorphisms and lung cancer.

MMP2 MMP13

1.50e-052135223465389
Pubmed

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4.

PCSK5 PCSK6

1.50e-05213528468318
Pubmed

Sidekicks: synaptic adhesion molecules that promote lamina-specific connectivity in the retina.

SDK2 SDK1

1.50e-052135212230981
Pubmed

Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1.

CEACAM5 CEACAM1

1.50e-052135215905509
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

1.50e-052135214985349
Pubmed

Mutation analysis of the Smad3 gene in human osteoarthritis.

MMP2 SMAD3

1.50e-052135212939660
Pubmed

Molecular basis of sidekick-mediated cell-cell adhesion and specificity.

SDK2 SDK1

1.50e-052135227644106
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP7P AGAP4 AGAP6

1.59e-0513135327713690
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP7P AGAP4 AGAP6

2.02e-0514135322453919
Pubmed

Host genetic control of mouse hepatitis virus type-4 (JHM strain) replication. II. The gene locus for susceptibility is linked to the Svp-2 locus on mouse chromosome 7.

GPI CEACAM5 CEACAM1

2.52e-051513536101098
Pubmed

Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.

PCSK5 PCSK6 PCSK7

3.09e-0516135320876279
Pubmed

Biglycan and decorin differentially regulate signaling in the fetal membranes.

MMP2 MMP13 SMAD3

3.09e-0516135324373743
Pubmed

ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging.

MMP2 MMP13

4.48e-053135217876296
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

4.48e-053135218403125
Pubmed

Expression and significance of TGF-beta1/Smad signaling pathway in children with IgA nephropathy.

SMAD3 SMAD7

4.48e-053135219693466
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

4.48e-053135229730765
Pubmed

Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat.

ZNF516 PRDM16

4.48e-053135225578880
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

4.48e-05313527876312
Pubmed

Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.

PCSK5 PCSK6

4.48e-05313528670066
Pubmed

Overexpression of MMP13 in human osteoarthritic cartilage is associated with the SMAD-independent TGF-β signalling pathway.

MMP13 SMAD3

4.48e-053135226395178
Pubmed

In situ localization of gelatinolytic activity during development and resorption of Meckel's cartilage in mice.

MMP2 MMP13

4.48e-053135217587297
Pubmed

Metalloproteinase expression in venous aneurysms.

MMP2 MMP13

4.48e-053135218971037
Pubmed

Carcinoembryonic antigen-related cell adhesion molecules (CEACAM) 1, 5 and 6 as biomarkers in pancreatic cancer.

CEACAM5 CEACAM1

4.48e-053135225409014
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

4.48e-053135222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

4.48e-053135210788707
Pubmed

Rab4b is a small GTPase involved in the control of the glucose transporter GLUT4 localization in adipocyte.

SLC2A4 RAB4A

4.48e-053135219590752
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

4.48e-05313527621815
Pubmed

Inhibitory potency and specificity of subtilase-like pro-protein convertase (SPC) prodomains.

PCSK5 PCSK7

4.48e-053135211723118
Pubmed

The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons.

RAPGEF4 PLCE1

4.48e-053135228209735
Pubmed

Association of functional polymorphisms in MMPs genes with gastric cardia adenocarcinoma and esophageal squamous cell carcinoma in high incidence region of North China.

MMP2 MMP13

4.48e-053135219562509
Pubmed

Subtilisin-like proprotein convertases, PACE4 and PC8, as well as furin, are endogenous proalbumin convertases in HepG2 cells.

PCSK6 PCSK7

4.48e-053135210050053
Pubmed

Evidence for TGF-beta1 and bleomycin intracellular signaling through autocrine regulation of Smad 3 binding to the proximal promoter of the Smad 7 gene.

SMAD3 SMAD7

4.48e-053135216187293
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

4.48e-053135210473538
Pubmed

RACK1 silencing attenuates renal fibrosis by inhibiting TGF-β signaling.

RACK1 SMAD3

4.48e-053135229039466
Pubmed

miR-29c in urinary exosomes as predictor of early renal fibrosis in lupus nephritis.

MMP2 SMAD3

4.48e-053135226040904
Pubmed

Prognostic impact of CEA/CA19-9 at the time of recurrence in patients with gastric cancer.

CEACAM5 CEACAM1

4.48e-053135233682011
Pubmed

Smad3-mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial-mesenchymal transition.

SETDB1 SMAD3

4.48e-053135229233829
Pubmed

Single nucleotide polymorphisms in the angiogenic and lymphangiogenic pathways are associated with lymphedema caused by Wuchereria bancrofti.

CEACAM1 MMP2

4.48e-053135229122006
Pubmed

The expression of TGF-β1, Smad3, phospho-Smad3 and Smad7 is correlated with the development and invasion of nonfunctioning pituitary adenomas.

SMAD3 SMAD7

4.48e-053135224636138
Pubmed

Inhibition of Smad signaling is implicated in cleft palate induced by all-trans retinoic acid.

SMAD3 SMAD7

4.48e-053135221555266
Pubmed

Thymosin beta4 promotes matrix metalloproteinase expression during wound repair.

MMP2 MMP13

4.48e-053135216607611
Pubmed

Sustained activation of fibroblast transforming growth factor-beta/Smad signaling in a murine model of scleroderma.

SMAD3 SMAD7

4.48e-053135212839562
Pubmed

Multiple exportins influence thyroid hormone receptor localization.

XPO4 XPO7

4.48e-053135225911113
Pubmed

Epinephrine-induced MMP expression is different between skeletal fibroblasts and myoblasts.

MMP2 MMP13

4.48e-053135221858843
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

4.48e-053135218434746
Pubmed

Loss of DJ-1 function contributes to Parkinson's disease pathogenesis in mice via RACK1-mediated PKC activation and MAO-B upregulation.

MAOB RACK1

4.48e-053135237225849
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

4.48e-05313529204703
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

4.48e-053135221881589
GeneFamilyProprotein convertase subtilisin/kexin family

PCSK5 PCSK6 PCSK7

1.27e-059983973
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL2 OSBPL3 OSBPL8

3.28e-0512983670
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

8.69e-053982287
GeneFamilyExportins

XPO4 XPO7

6.00e-047982547
GeneFamilyImmunoglobulin like domain containing

SDK2 CEACAM5 CEACAM1 KIRREL3 IGSF21 SDK1

6.39e-04193986594
GeneFamilyArfGAPs

AGAP7P AGAP4 AGAP6

7.49e-0433983395
GeneFamilySMAD family

SMAD3 SMAD7

7.97e-048982750
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SDK2 CEACAM5 MYOM1 KIRREL3 SDK1

1.84e-03161985593
GeneFamilyWD repeat domain containing

EML6 COP1 EML5 RACK1 STRAP EML1

3.03e-03262986362
GeneFamilyDyneins, axonemal

DNAH10 DNAH2

3.75e-0317982536
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP4 AGAP6

3.75e-03179821291
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

SQSTM1 UTRN

4.20e-031898291
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

OSBPL3 OSBPL8 AGAP7P AGAP4 AGAP6

5.28e-03206985682
GeneFamilyRAB, member RAS oncogene GTPases

RAB40A RAB40B RAB4A

5.29e-0365983388
GeneFamilyDNA polymerases

POLM REV3L

6.83e-0323982535
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

FCHSD2 FES

6.83e-03239821288
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP2 MMP13

7.43e-0324982891
GeneFamilyCD molecules|V-set domain containing|Immunoglobulin like domain containing|Carcinoembryonic antigen related cell adhesion molecule family

CEACAM5 CEACAM1

7.43e-0324982906
GeneFamilyFibronectin type III domain containing

SDK2 MYOM1 PTPRH SDK1

1.12e-02160984555
GeneFamilyAdenosine receptors|V-set domain containing

CEACAM5 CEACAM1 LY6G6F IGSF21

1.19e-02163984590
CoexpressionDESCARTES_FETAL_SPLEEN_MEGAKARYOCYTES

MYOM1 F13A1 MMRN1 EFHC2 LY6G6F MYO3B KBTBD12

2.04e-061141347M40293
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 SDK2 RYR3 MMRN1 LY6G6F IQCA1 IGSF21

8.40e-0812013572b7596946f9268c4202348adf3069decd8313bb0
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 MROH2A RYR2 RYR3 LRP2 SDK1 ADGRL3 PLCE1

9.56e-0818413582cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 MROH2A RYR2 RYR3 LRP2 SDK1 ADGRL3 PLCE1

9.56e-081841358ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 MROH2A RYR2 RYR3 LRP2 SDK1 ADGRL3 PLCE1

9.56e-0818413582b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYOM1 F13A1 MMRN1 EFHC2 GLYATL1 LY6G6F KBTBD12

7.33e-071651357d2ab667ff53f538b12ee4e07ea4b4d118600a228
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 DNAH10 MROH2A RYR2 RYR3 MYO3B LRP2

8.61e-07169135712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A DNAH10 ATP8A2 TCIRG1 RYR3 MMRN1 PLCE1

1.58e-061851357bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 ARSJ EML5 OSBPL3 C5 PRDM16 UTRN

1.63e-0618613574e94158db52df41d71e67b02b9895a358eebee0f
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

TNIK PCSK5 RRAS2 DOCK8 GLYATL1 LRP2 SDK1

1.69e-061871357d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK8 ADGRE2 CREG1 F13A1 FCHSD2 FES IGSF21

1.75e-0618813573be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCellsevere_influenza-Platelet|World / disease group, cell group and cell class (v2)

MASP1 MAOB OAZ1 F13A1 MMRN1 LY6G6F PCSK6

1.75e-061881357b54632baa682aaf51100d44e7f114a54d5edd695
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 RYR2 KBTBD12 PRDM16 SDK1 ADGRL3 PLCE1

1.82e-0618913577fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 RYR2 KBTBD12 PRDM16 SDK1 ADGRL3 PLCE1

1.82e-06189135706b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell10x5'v1-week_14-16-Hematopoietic-MK-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK MYOM1 F13A1 RYR2 MMRN1 EFHC2 LY6G6F

2.02e-061921357b877d14be9d04ab0010e340909e3a23de92613db
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAOB OAZ1 F13A1 MMRN1 LY6G6F PCSK6 RAB4A

2.09e-061931357a2fb7482e79d6ce5b6b1d9d0c0811d1c58b4d85d
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAOB OAZ1 F13A1 MMRN1 LY6G6F PCSK6 RAB4A

2.09e-0619313571d724ccb745cfc624119dd6003d53b84b17c94b0
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 IQCA1 MDH1B

2.24e-061951357e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQCH DNAH10 SYNE1 DNAH2 MAPK15 OSBPL3 MDH1B

2.39e-06197135774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIK SYNE1 CYP51A1 ARHGEF38 LRP2 C5 DMBT1

2.56e-0619913572dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

IQCH DNAH10 EML6 DNAH2 MAPK15 TMEM232 MDH1B

2.64e-06200135796701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYOM1 SYNE1 SLC2A4 RYR2 EGFL6 SLC20A2 PLCE1

2.64e-062001357c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 IQCA1 MDH1B

2.64e-0620013575abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 IQCA1 MDH1B

2.64e-0620013579c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Glia_progenitor_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

DOCK8 TCIRG1 SFMBT2 EGFL6 MMRN1 FES MMP2

2.64e-0620013574b937b1d0179d1d0e51931f35720e205d460a07e
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 MASP1 SDK2 MMRN1 LY6G6F IGSF21

4.40e-06140135617005ca714ba03d7528fe7979ffb4654a46b666c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 IVNS1ABP LRP2 CD200R1L PRDM16 SDK1

6.80e-061511356f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARSJ PTPRH OSBPL3 KBTBD12 PRDM16 SVOP

7.34e-0615313560a4fbe46125b05ee235deb528855808c2bf33cba
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYOM1 F13A1 RYR3 EFHC2 GLYATL1 LY6G6F

8.82e-061581356944c5fe625f965dd6153dbcbf5577f99ad343983
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SDK2 NUP210L ATP8A2 DNAH2 LRP2 SVOP

1.21e-0516713563edb0570e583bb527165bcd8a4c25a042054043b
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYOM1 F13A1 MMRN1 EFHC2 LY6G6F KBTBD12

1.34e-0517013563886a77bc3ddbeb42a8149b759fe578871676d6e
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

DENND4A SYNE1 HELB PCSK7 UTRN ZG16

1.38e-0517113562e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellControl-Myeloid-Dendritic_cells|Control / group, cell type (main and fine annotations)

DOCK8 ADGRE2 SFMBT2 F13A1 GLYATL1 IGSF21

1.85e-05180135625ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 MAPK15 TMEM232 IQCA1 MDH1B LRP2

2.03e-0518313566ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MYOM1 F13A1 MMRN1 EFHC2 LY6G6F GABBR1

2.03e-0518313566cbc88c27dc957d182526e84824f70c8e860bf74
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 MAPK15 TMEM232 IQCA1 MDH1B LRP2

2.03e-05183135618040d0653286071df959513c63d94b555a5d00a
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYOM1 F13A1 RYR2 MMRN1 EFHC2 LY6G6F

2.09e-051841356ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MROH2A ARHGEF38 LRP2 C5 HAS3 PRDM16

2.09e-051841356fa4915b0498f3069fd5ef497286445528f75187e
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 MDH1B

2.16e-0518513565e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCelldroplet-Lung-nan-18m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 DNAH10 MAPK15 TMEM232 IQCA1 MDH1B

2.22e-051861356740fd06bcd3b24e6ff2ecf8080f378afc3e95084
ToppCellmegakaryocytic-Megakaryocyte|World / Lineage and Cell class

MAOB F13A1 RYR2 MMRN1 EFHC2 LY6G6F

2.22e-051861356acd15a169b6122b28cc99ef34de10701edcfedfe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK MASP1 DOCK8 IQCA1 LRP2 SDK1

2.22e-051861356f28d72b47624b69a580b4429e2be560a26898591
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOM1 SYNE1 SLC2A4 RYR2 EGFL6 SDK1

2.22e-0518613564780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCelldroplet-Lung-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 DNAH10 MAPK15 TMEM232 IQCA1 MDH1B

2.22e-0518613565ab43a298d23238b34e898d11decf0ad81d1b14e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 DOCK8 RYR2 SORBS3 ADGRL3 PLCE1

2.29e-05187135648bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 IQCA1 OSBPL3 C5 PRDM16 UTRN

2.29e-05187135658d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 DOCK8 RYR2 SORBS3 ADGRL3 PLCE1

2.29e-051871356958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 MDH1B

2.36e-05188135661a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

RYR2 RYR3 SLC20A2 PRDM16 SDK1 ADGRL3

2.36e-05188135634e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8A2 MMRN1 FAM171A2 PCSK6 HAS3 PLCE1

2.36e-051881356a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8A2 MMRN1 FAM171A2 PCSK6 HAS3 PLCE1

2.36e-05188135654550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPPK1 DNAH10 MAPK15 TMEM232 IQCA1 MDH1B

2.36e-0518813560eca3dc93724e23b71e687fc24fa9f1e89bdef6a
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 MDH1B

2.36e-0518813562b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPPK1 DNAH10 MAPK15 TMEM232 IQCA1 MDH1B

2.36e-0518813569ce3e1fffce87ad19812ecbf9b7f9935a975d676
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAOB OAZ1 F13A1 MMRN1 LY6G6F PCSK6

2.43e-051891356d357fa946b9d6af46c15402f68758fb9c747bcaf
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAOB OAZ1 F13A1 MMRN1 LY6G6F PCSK6

2.43e-0518913568b4a9434d7b7ca8cf74712227407ed7c96ce02f8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 DOCK8 RYR2 SORBS3 ADGRL3 PLCE1

2.43e-051891356fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 EML6 OSBPL3 MYO3B PRDM16 UTRN

2.43e-051891356830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPPK1 DNAH10 MAPK15 TMEM232 IQCA1 MDH1B

2.43e-051891356fe958fdf9963c2dfe270f67f0da36b3264d0017c
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 MDH1B

2.43e-051891356b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 MAOB ADGRE2 RYR2 MMP2 SDK1

2.43e-0518913562a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 MDH1B

2.43e-05189135627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCiliated|World / shred by cell class for parenchyma

DNAH10 DNAH2 EFHC2 MAPK15 TMEM232 MDH1B

2.43e-051891356711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATP8A2 MMRN1 FAM171A2 PCSK6 HAS3 PLCE1

2.51e-051901356e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATP8A2 MMRN1 FAM171A2 PCSK6 HAS3 PLCE1

2.51e-051901356f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARSJ SLC2A4 EGFL6 IVNS1ABP MAPK15 PCSK6

2.51e-05190135668ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATP8A2 MMRN1 FAM171A2 PCSK6 HAS3 PLCE1

2.51e-051901356b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOM1 SLC2A4 RYR2 EGFL6 SDK1 PLCE1

2.51e-05190135673d94fbae92029745989a8712eed8b99fd84c193
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPI ARHGEF38 IVNS1ABP OSBPL3 MYO3B PRDM16

2.51e-0519013563dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARSJ SLC2A4 EGFL6 IVNS1ABP MAPK15 PCSK6

2.51e-051901356010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC2A4 EGFL6 IVNS1ABP MAPK15 PCSK6 PRDM16

2.58e-0519113565a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC2A4 EGFL6 IVNS1ABP MAPK15 PCSK6 PRDM16

2.58e-05191135678bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK MYOM1 RYR2 MMRN1 EFHC2 LY6G6F

2.58e-0519113567edc22e7e70697fb22690699efb352577162709b
ToppCellLAM-Epithelial-AirwayEpi|LAM / Condition, Lineage and Cell class

KLK10 DNAH2 MAPK15 TMEM232 IQCA1 MDH1B

2.66e-0519213567404fc65be3b7bd09447725b43fa31819004dfee
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND4A PDE8A COP1 TXNRD1 FCHSD2 UTRN

2.74e-051931356779276e775cb2492e8dd36436295a536084a6415
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

TNIK RRAS2 MYOM1 RYR2 SLC20A2 PRDM16

2.74e-051931356dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellsevere_COVID-19-Platelet|World / disease group, cell group and cell class (v2)

MAOB OAZ1 F13A1 MMRN1 LY6G6F PCSK6

2.74e-051931356a598a0665652cc365eb08e413a711c929b80fec7
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte|World / Lineage, cell class and subclass

MAOB F13A1 RYR2 EGFL6 MMRN1 LY6G6F

2.74e-051931356352cd442b6e62f09b6d22a139774067873644594
ToppCellLA|World / Chamber and Cluster_Paper

PCSK5 F13A1 KIRREL3 PCSK6 LRP2 SDK1

2.74e-051931356d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 RYR2 UTRN SDK1 ADGRL3 PLCE1

2.82e-0519413565c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 RYR2 UTRN SDK1 ADGRL3 PLCE1

2.82e-051941356ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ASNSD1 REV3L ADGRE2 PCSK6 UTRN PLCE1

2.82e-051941356dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 SYNE1 DNAH2 EFHC2 MAPK15 TMEM232

2.90e-0519513563486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 EFHC2 MAPK15 TMEM232 IQCA1 MDH1B

2.90e-05195135607a6bcef6af93ed87df455dee624037cb75e011a
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DNAH10 MROH2A RYR3 LRP2 MMP2

2.98e-0519613566bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DNAH10 MROH2A RYR3 LRP2 MMP2

2.98e-051961356c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK MYOM1 RYR2 MMRN1 EFHC2 LY6G6F

2.98e-05196135666ba31b74953726e9c314f6d8fe3f75d3762e23a
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH2 MAPK15 TMEM232 IQCA1 MDH1B

2.98e-051961356686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH10 DNAH2 MAPK15 TMEM232 IQCA1 MDH1B

2.98e-05196135667aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 DNAH2 MAPK15 TMEM232 IQCA1 MDH1B

2.98e-051961356ca56311edc6788e032e7635fa69b1e07035202b5
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DNAH10 DNAH2 MAPK15 TMEM232 IQCA1 MDH1B

2.98e-0519613561cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellsevere_COVID-19-Platelet|severe_COVID-19 / disease group, cell group and cell class (v2)

OAZ1 F13A1 MMRN1 LY6G6F PCSK6 RAB4A

2.98e-0519613562b835fc3db81550555cbbcb3e823d9197ee35662
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH2 MAPK15 TMEM232 IQCA1 MDH1B

2.98e-05196135669f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

DNAH10 SYNE1 MAPK15 TMEM232 IQCA1 MDH1B

3.07e-051971356fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK SYNE1 HELB ZBTB37 PCSK7 UTRN

3.07e-051971356e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SYNE1 CYP51A1 IQCA1 LRP2 C5 DMBT1

3.07e-051971356fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

TNIK SDK2 MAOB RYR2 OSBPL8 MMP2

3.07e-051971356f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-myelocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GPI EPPK1 SYNE1 CEACAM1 IVNS1ABP METTL9

3.16e-0519813563bc05b8d97a7219af40db7a11aa271f02e74fca5
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK SYNE1 HELB ZBTB37 PCSK7 UTRN

3.25e-051991356f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellmedial-Epithelial-Ciliated-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAH10 DNAH2 MAPK15 TMEM232 IQCA1 MDH1B

3.25e-051991356526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 ADGRE2 SFMBT2 F13A1 IGSF21 UTRN

3.25e-051991356f34c15df58fbdc6c90e30800e26fabbf828ad10b
DrugD3273

MMRN1 C5 MMP2 MMP13 CABIN1 SMAD3 SMAD7

1.40e-06941347CID005464587
DrugAzathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A

CEACAM5 ARSJ MAOB AOC2 ARHGEF38 F13A1 CEACAM1 EFHC2 MMP13

2.50e-0619613495627_UP
Diseasecerebral palsy (implicated_via_orthology)

AGAP7P AGAP4 AGAP6

1.05e-05101333DOID:1969 (implicated_via_orthology)
Diseasepulmonary hypertension (biomarker_via_orthology)

SLC2A4 RYR2 RYR3 HAS3 SMAD7

3.16e-05801335DOID:6432 (biomarker_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

6.03e-0531332DOID:3529 (implicated_via_orthology)
Diseasecomplement C5B-C6 complex measurement

NPEPPS C5

6.03e-0531332EFO_0020279
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

6.03e-0531332DOID:8545 (implicated_via_orthology)
Diseasehippocampal volume

TNIK EPPK1 CYP51A1 RAPGEF4 RYR2 RYR3 EML1 SMAD7

6.33e-052971338EFO_0005035
DiseaseCraniofacial Abnormalities

MASP1 RAB40AL LRP2 MMP2 MMP13 SMAD3

7.82e-051561336C0376634
Diseasegastric ulcer (biomarker_via_orthology)

F13A1 MMP2 MMP13

1.12e-04211333DOID:10808 (biomarker_via_orthology)
Diseasearteriosclerosis (is_implicated_in)

F13A1 MMP2 MMP13

3.67e-04311333DOID:2349 (is_implicated_in)
Diseasebehavioural disinhibition measurement

MASP1 ARSJ KIRREL3 MMP2

3.74e-04751334EFO_0006946
Diseaseanxiety, vitamin D measurement

DOCK8 TMCO3

4.17e-0471332EFO_0004631, EFO_0005230
Diseaseurate measurement, bone density

SYNE1 THAP9 SFMBT2 CCER1 SLC6A2 KIRREL3 ZNF516 DMBT1 CABIN1 UTRN

5.15e-0461913310EFO_0003923, EFO_0004531
Diseasecoronary artery disease

DNAH10 DOCK8 F13A1 FES C5 EML1 MMP13 CABIN1 PRDM16 ADGRL3 GABBR1 SMAD3 SMAD7 PLCE1

1.02e-03119413314EFO_0001645
Diseaseamino acid measurement

SYNE1 SLC2A4 RYR2 RYR3 SLC6A2 MMRN1 OSBPL2 PCSK6 LRP2 C5

1.03e-0367813310EFO_0005134
DiseaseColorectal Neoplasms

SYNE1 TXNRD1 STRAP MMP2 SMAD3 SMAD7

1.64e-032771336C0009404
Diseaseglucose metabolism measurement, age-related hearing impairment

PCSK5 GTF2F2 SMAD3

1.68e-03521333EFO_0005782, EFO_0009367
DiseaseMetabolic Bone Disorder

LRP2 MMP2

1.77e-03141332C0005944
Diseaseovarian carcinoma (is_implicated_in)

MMP13 CABIN1

2.04e-03151332DOID:4001 (is_implicated_in)
DiseaseOsteopenia

LRP2 MMP2

2.04e-03151332C0029453
DiseasePulmonary Emphysema

MMP2 SMAD3

2.62e-03171332C0034067
Diseaseunipolar depression, bipolar disorder, schizophrenia

PCSK5 METTL9

3.63e-03201332EFO_0003761, MONDO_0004985, MONDO_0005090
DiseaseST2 protein measurement

KIRREL3 MAP4K4

4.00e-03211332EFO_0010599
Diseaseperiodontitis (biomarker_via_orthology)

MMP2 MMP13

4.00e-03211332DOID:824 (biomarker_via_orthology)
DiseaseNasopharyngeal carcinoma

SYNE1 MMP2

4.39e-03221332C2931822

Protein segments in the cluster

PeptideGeneStartEntry
KGNVVLAQLLIWYGV

AGAP4

611

Q96P64
ILWDGFTGQRSKVYQ

COP1

496

Q8NHY2
WKTGKIQLYQGTDAT

EGFL6

501

Q8IUX8
LSQQVREQYGKWSKG

ADGRE2

781

Q9UHX3
TSRWLVDTGNVKGYV

ARHGEF38

621

Q9NXL2
SWYKGERVDGNRQII

CEACAM5

66

P06731
GLWVIYATEQNNGKI

ADGRL3

271

Q9HAR2
KETWGLQETLYGFVQ

CCER1

241

Q8TC90
YVLWKQIIERNGGVL

IQCA1

711

Q86XH1
LRNTQWVFGIVVYTG

ATP8A2

276

Q9NTI2
KGNVVLAQLLIWYGV

AGAP6

611

Q5VW22
TQIFGVGVKTADRWY

POLM

241

Q9NP87
ELWTLGEGQVVRVKY

MMP2

211

P08253
SGYFLWTKVRNVVLG

DENND4A

866

Q7Z401
GAQGVILVYDIANRW

RAB40A

86

Q8WXH6
GAQGVILVYDIANRW

RAB40B

86

Q12829
GAQGVILVYDIANRW

RAB40AL

86

P0C0E4
GYTDNLVRVWQVTIG

RACK1

301

P63244
NVGGKYVKLQIWDTA

RAB4A

56

P20338
FYRQQKWASGVIAIA

IQCH

391

Q86VS3
QNWRVYDVLVLKGSQ

LY6G6F

116

Q5SQ64
LSWGRYQLVVTQRKE

AOC2

621

O75106
LWYVKQCGGTTRIIS

MAOB

186

P27338
TYGRITKDVVLQWGE

MAP4K4

1146

O95819
NGKLYTKVINWVQRS

IVNS1ABP

191

Q9Y6Y0
VIEQSYNETWLGRQG

SLC2A4

51

P14672
NYGQEVWLRLAKGTI

MMRN1

1196

Q13201
QGAYGIVWKAVDRRT

MAPK15

21

Q8TD08
WTLIEQLQGGSYKKI

GABBR1

536

Q9UBS5
AGYGIWNTAIQSAIR

ARSJ

436

Q5FYB0
YFEWAAQVVKGLQGT

HDDC3

146

Q8N4P3
AALRQKVQQWYTAVG

KIAA2026

371

Q5HYC2
ATKQEYWGNGTVTVK

CD200R1L

181

Q6Q8B3
GVTINVWGRKVLLYD

EFHC2

341

Q5JST6
TVTEGGVKQEYRTWN

FBLL1

136

A6NHQ2
WKRGYTGKNIVVTIL

PCSK5

156

Q92824
VQAAWKRGYTGKNVV

PCSK6

186

P29122
QVGILRQWQLTLYGS

PCSK7

601

Q16549
TGKTLLFSGNQVWRY

MMP13

391

P45452
NGLTRWAKEIENGVY

ODR4

206

Q5SWX8
INSCIRIGKEWQGIY

PDE8A

276

O60658
VSYSGLVNDNWKRGK

GLYATL1

176

Q969I3
KKYRVLGINEWQNTG

METTL9

186

Q9H1A3
GEVNDIKTRSWSYGQ

F13A1

216

P00488
WKGYTGKTITDVINI

GPI

141

P06744
QKLYWAVTGRGVIER

LRP2

1931

P98164
KRINWRTVLSGGSLY

OAZ1

126

P54368
GTGVIRKEGRQLYWT

FAM171A2

266

A8MVW0
LLIYKTQKNGQWVGT

OSBPL8

176

Q9BZF1
EIVWYRVTDGGTIKQ

IGSF21

56

Q96ID5
GKTLLLDAYRVWQQG

CABIN1

1856

Q9Y6J0
LDAYRVWQQGQKGVA

CABIN1

1861

Q9Y6J0
QAEVGEWLRIGNKYI

C5orf60

76

A6NFR6
QKQGASVETLLGYSW

DOCK8

656

Q8NF50
SWYKGERVDGNRQIV

CEACAM1

66

P13688
QAYKGWQLSTKEGVR

DHX57

1126

Q6P158
TGRVVGILQKNWRDY

DIS3L

331

Q8TF46
QKRGNSTVYEWRTGT

CDK5RAP3

231

Q96JB5
IFLGKTWGQEQTYVI

C5

11

P01031
TLWGVGQSNYLEKNR

C4orf17

61

Q53FE4
IGENFAYVQIKTIWS

CYP51A1

456

Q16850
KGNVVLAQLLIWYGV

AGAP7P

611

Q5VUJ5
QRKLWVGYQYVITGR

DGCR2

181

P98153
KDVIIWGNISGNNYV

MDH1B

306

Q5I0G3
WGNISGNNYVDLRKT

MDH1B

311

Q5I0G3
VTLNRERGQWYLVGT

MASP1

651

P48740
IGWLVAQEGVKSYQS

ASNSD1

471

Q9NWL6
SVSKWVRLNVGGTYF

KCTD5

41

Q9NXV2
IIWLRKGEVINGATY

KIRREL3

181

Q8IZU9
VGGDVQILNKYDSWI

HAS3

241

O00219
VQEVGGSYWQRVTLI

HEATR1

1196

Q9H583
ILVWGKGTNRISYAV

EML1

441

O00423
YVWKGINLIRTIQGA

EML5

221

Q05BV3
YVWKGLNLVRTIQGA

EML6

221

Q6ZMW3
QVGKFDWRQQYVGKV

EMC1

26

Q8N766
KLNITNIWVLDYFGG

CREG1

191

O75629
DWVKARNKVGQVGYV

FCHSD2

506

O94868
QGRVEVLYRGSWGTV

DMBT1

1261

Q9UGM3
KRLNWNSLGIGDYIT

DNAH10

746

Q8IVF4
TNYRDEIVNQIWIGK

DNAH2

3326

Q9P225
LEKNGIITGYQISWE

SDK1

996

Q7Z5N4
GVYSSKVTEWTLQGV

SDK2

776

Q58EX2
ALWLIYKQGGVTQEA

SLC20A2

516

Q08357
RIRQGWTYGIQQDVK

RYR2

1011

Q92736
DQWVKLNLGTVGFYR

NPEPPS

576

P55786
TVVYVVGKAGRQHWQ

HELB

896

Q8NG08
GQRWIEHYGEIVIKN

OSBPL3

696

Q9H4L5
GNRWSLEVGQVYVIT

NUP210L

366

Q5VU65
VVTVNNKLYVIGGWT

KBTBD12

431

Q3ZCT8
QERIKGWGLKYLSVQ

MROH2A

461

A6NES4
QGKQEYVLSVLWDGL

FES

486

P07332
RSSYVITTKIFWGGQ

KCNAB3

151

O43448
YLSQQWAKASGRGEV

GTF2F2

26

P13984
LGQYNREGAATVWKI

SLC6A2

116

P23975
LNWLLNVYDTGRTGK

UTRN

2936

P46939
GTSWYIILKGSVNVV

RAPGEF4

391

Q8WZA2
QYGRKTGLKISVLWT

SVOP

146

Q8N4V2
GIYALWKRSIQSIQK

TMCO2

66

Q7Z6W1
SQYIKWIVSAGLAQV

TMCO3

606

Q6UWJ1
KWVQYTAGKQTGIEV

SYNE1

186

Q8NF91
GALSKWTSYQDGVRQ

SYNE1

3386

Q8NF91
IGLTAWSYIDQKRNG

PLCE1

356

Q9P212
QGQAAVTIQKVWKGY

IQCA1L

206

A6NCM1
NQAGAGSWLKYIRVA

PRDM16

161

Q9HAZ2
VKYGRFQGQRVSAWE

EPPK1

821

P58107
GVVWLIRNGSIYINE

NAGPA

201

Q9UK23
WRDGSGQEKYRLVVV

RRAS2

6

P62070
YQIIEDAGNKGIWSR

POLR3F

96

Q9H1D9
LWYALSAGGNVVNKV

SLC35E1

36

Q96K37
NVIIGKLWIEQYGTV

OSBPL2

241

Q9H1P3
DGTLRLWQTVVGKTY

STRAP

286

Q9Y3F4
GWLTRLLQTKNYDIG

SQSTM1

411

Q13501
GSRVVAKYKDGNQVW

SETDB1

261

Q15047
LGQALQDSRNYGWKV

TXNRD1

226

Q16881
YQAWQLATRGKVAEP

ZNF516

416

Q92618
QISFVKGWGQCYTRQ

SMAD7

396

O15105
NTYGRITKDVVLQWG

TNIK

1266

Q9UKE5
YGRKQVSWIIFLKIG

nan

36

Q8N2B8
DTEGSQWIIGYLLQK

XPO4

671

Q9C0E2
ILRINRAGQWYVETG

ZBTB37

211

Q5TC79
LVNDTKKWGARVVYG

REV3L

2766

O60673
RKDLALWTVQRQYGV

THAP9

666

Q9H5L6
KDRIKQGWTYGIQQD

RYR3

996

Q15413
FVKGWGAEYRRQTVT

SMAD3

376

P84022
GLVYNLVKISWELQG

TMEM232

436

C9JQI7
VGVSKQDIREQIWGY

MTHFSD

6

Q2M296
FQYWIVSVIENVGGR

SFMBT2

201

Q5VUG0
KVNENWYEGRITGTG

SORBS3

486

O60504
NYWNTKIGLQVKELG

SMCO2

131

A6NFE2
IVGLQVRYGKVWSDY

ZG16

61

O60844
VGLSVVGQLYLRWKE

SLC7A6

401

Q92536
TQYVKWTNDKSLGGI

TTC38

36

Q5R3I4
VFIGKIITNLKYWGR

XPO7

591

Q9UIA9
IVKWGGQEYSVTTLS

UBLCP1

6

Q8WVY7
LYVFSVWVGKNGINS

PTPRH

361

Q9HD43
WGLLNVTQKGLYRDV

ZNF584

31

Q8IVC4
ISYWGEQIGQKIRKI

TCIRG1

221

Q13488
REVQKQETWVFLVYG

TMEM249

81

Q2WGJ8
QWNKIYSVETGLLGT

nan

26

Q8N9L7
VAGWGTTAARRVKYN

KLK10

171

O43240
IGRVVVLQAYTKGWL

MYO3B

1061

Q8WXR4
YSDRVKTGVTGEQIW

MYOM1

1501

P52179