Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	mercury ion binding	PARK7 TXNRD1 P2RX2	2.90e-05	8	163	3	GO:0045340
GeneOntologyMolecularFunction	chloride:monoatomic cation symporter activity	SLC6A3 SLC6A8 SLC12A4 SLC12A7	3.36e-05	23	163	4	GO:0015377
GeneOntologyMolecularFunction	monoatomic anion:monoatomic cation symporter activity	SLC6A3 SLC6A8 SLC12A4 SLC12A7	5.56e-05	26	163	4	GO:0015296
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	DPYSL2 MTHFD2 ASAH2 PARK7 CD101 PADI2 ASAH2B	1.99e-04	146	163	7	GO:0016810
GeneOntologyMolecularFunction	fibronectin binding	TNC ITGB3 LOXL3 MMP13	2.54e-04	38	163	4	GO:0001968
GeneOntologyMolecularFunction	calcium ion binding	DSG1 ASAH2 SPTAN1 FKBP9 ITLN2 MYOF CDH20 USP32 FKBP7 PLCB2 MMP13 PADI2 PCDH1 PCDH18 CDH11 ASAH2B	4.30e-04	749	163	16	GO:0005509
GeneOntologyBiologicalProcess	regulation of dopamine metabolic process	PARK7 ITGAM SLC6A3 HPRT1	2.82e-05	23	161	4	GO:0042053
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	RELN PARK7 L1CAM CPEB3 CHRNA5 CHRNA7 SLC6A3 MET MYOF OSBPL2 SLC12A4 SYNJ1 P2RX2 KDR KIF5A BSN SLC12A7 IGSF21 CDH11 CA7	3.99e-05	931	161	20	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	RELN PARK7 L1CAM CPEB3 CHRNA5 CHRNA7 SLC6A3 MET MYOF OSBPL2 SLC12A4 SYNJ1 P2RX2 KDR KIF5A BSN SLC12A7 IGSF21 CDH11 CA7	3.99e-05	931	161	20	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	RELN PARK7 L1CAM CPEB3 CHRNA5 CHRNA7 SLC6A3 MET MYOF OSBPL2 SLC12A4 SYNJ1 P2RX2 KDR KIF5A BSN SLC12A7 IGSF21 CDH11 CA7	4.50e-05	939	161	20	GO:0099537
GeneOntologyBiologicalProcess	regulation of catecholamine metabolic process	PARK7 ITGAM SLC6A3 HPRT1	4.68e-05	26	161	4	GO:0042069
GeneOntologyBiologicalProcess	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	DSG1 CDH20 PCDH1 PCDH18 CDH11	5.77e-05	53	161	5	GO:0016339
GeneOntologyBiologicalProcess	cell junction organization	CACNA1S RELN SDK2 DSG1 DSP TNC L1CAM CPEB3 CSMD2 ITGAM ITGB3 CHRNA7 NEDD9 ARHGAP6 CDH20 P2RX2 KDR BSN IGSF21 CDH11	7.45e-05	974	161	20	GO:0034330
GeneOntologyBiologicalProcess	synaptic signaling	RELN PARK7 L1CAM CPEB3 CHRNA5 CHRNA7 SLC6A3 MET MYOF OSBPL2 SLC12A4 SYNJ1 P2RX2 KDR KIF5A BSN SLC12A7 IGSF21 CDH11 CA7	7.67e-05	976	161	20	GO:0099536
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	SDK2 DSG1 L1CAM CDH20 IGSF21 PCDH1 PCDH18 CDH11	1.13e-04	187	161	8	GO:0007156
GeneOntologyCellularComponent	plasma membrane raft	ASAH2 ITGAM CHRNA7 SLC6A3 MYOF SCARB1 ASAH2B	1.70e-04	147	165	7	GO:0044853
GeneOntologyCellularComponent	synaptic membrane	L1CAM CSMD2 ITGB3 CHRNA5 CHRNA7 SLC6A3 SLC6A8 MET SLC16A3 SYNJ1 P2RX2 BSN AKAP1 IGSF21	2.24e-04	583	165	14	GO:0097060
GeneOntologyCellularComponent	anchoring junction	FLNC DSG1 DSP TNC RPS3A PARK7 SPTAN1 L1CAM ZNF185 ITGB3 PGM5 NEDD9 CDH20 MDC1 KDR MMP13 IGSF21 PCDH1 CDH11	2.63e-04	976	165	19	GO:0070161
GeneOntologyCellularComponent	postsynapse	CACNA1S DPYSL2 RPS3A SPTAN1 CPEB3 CSMD2 ITGB3 HNRNPD CHRNA5 CHRNA7 SLC6A3 SLC6A8 MET SLC16A3 P2RX2 KIF5A BSN AKAP1 IGSF21	4.43e-04	1018	165	19	GO:0098794
GeneOntologyCellularComponent	membrane raft	ASAH2 PARK7 ITLN2 ITGAM CHRNA7 SLC6A3 MYOF SCARB1 KDR ASAH2B	6.24e-04	362	165	10	GO:0045121
GeneOntologyCellularComponent	membrane microdomain	ASAH2 PARK7 ITLN2 ITGAM CHRNA7 SLC6A3 MYOF SCARB1 KDR ASAH2B	6.51e-04	364	165	10	GO:0098857
GeneOntologyCellularComponent	cholinergic synapse	CHRNA5 CHRNA7 PLD1	6.66e-04	22	165	3	GO:0098981
MousePheno	decreased embryonic cilium number	INTU MKS1 B9D1	1.84e-05	6	138	3	MP:0013197
Domain	Ceramidse_alk_C	ASAH2 ASAH2B	7.48e-05	2	162	2	PF17048
Domain	NEUT/ALK_ceramidase_C	ASAH2 ASAH2B	7.48e-05	2	162	2	IPR031331
Domain	Ceramidase_alk	ASAH2 ASAH2B	7.48e-05	2	162	2	IPR006823
Domain	B9_dom	MKS1 B9D1	2.23e-04	3	162	2	IPR010796
Domain	B9	MKS1 B9D1	2.23e-04	3	162	2	PS51381
Domain	B9-C2	MKS1 B9D1	2.23e-04	3	162	2	PF07162
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	DPYSL2 ACACA DSP NOA1 PARK7 SPTAN1 HSPH1 L1CAM CYP51A1 FKBP9 PAICS TXNDC12 BUD23 MET MYOF TUBB4B PRRC2C HPRT1 SCARB1 MDC1 NUP210 TMX3 POGLUT2 AKAP1 G6PD CRTAP	5.53e-10	1297	165	26	33545068
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	EPRS1 FLNC RAP1GAP ACACA DSG1 DSP TNC MTHFD2 RPS3A SPTAN1 HSPH1 ZNF185 TUBB4B PRRC2C GCN1 ALPG	1.77e-09	488	165	16	31324722
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	EPRS1 FLNC DPYSL2 ACACA DSG1 DSP RPS3A PARK7 SPTAN1 HSPH1 ZNF185 PFKL PAICS HNRNPD NUP205 BUD23 TUBB4B UPF2 MDC1 SMARCA1 AATF GCN1 MVP G6PD PCK2	6.32e-09	1353	165	25	29467282
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	EPRS1 FLNC DPYSL2 DSG1 DSP RPS3A NUP205 MYOF TUBB4B GCN1 MVP G6PD	3.66e-08	312	165	12	37120454
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	DPYSL2 FRAS1 HSPH1 L1CAM CYP51A1 FKBP9 PAICS CHRNA5 TXNDC12 SLC6A8 MET MYOF CSGALNACT2 SLC16A3 SCARB1 NUP210 FKBP7 TMX3 POGLUT2 AKAP1 G6PD CRTAP	6.54e-08	1201	165	22	35696571
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLNC FRAS1 ACACA MFHAS1 FOSL2 MEX3D L1CAM CEP192 REXO1 ADCY7 SLC6A8 MYOF KMT2D SLC12A4 SYNJ1 ZNRF3 SCARB1 PCYT2 ARRDC2 GCN1 MED13	7.25e-08	1105	165	21	35748872
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EPRS1 ACACA DNAH10 DSG1 DSP RPS3A PARK7 SPTAN1 RGS22 HSPH1 PFKL OLA1 PAICS HNRNPD NUP205 CLPB HPRT1 MDC1 NUP210 SMARCA1 MTR BSN GCN1 G6PD	7.47e-08	1425	165	24	30948266
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	EPRS1 FLNC ACACA DSG1 DSP RPS3A SPTAN1 PAICS HNRNPD TUBB4B CILP2 NUP210 GCN1 PCK2	7.55e-08	477	165	14	31300519
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	EPRS1 FLNC DPYSL2 RAP1GAP DSP TNC RPS3A PARK7 SPTAN1 HSPH1 L1CAM ZNF185 FKBP9 PFKL OLA1 HNRNPD TUBB4B AGO1 CLCN6 UPF2 SYNJ1 PRRC2C BSN PCDH1	8.08e-08	1431	165	24	37142655
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CACNA1F EPRS1 CRISP2 DPYSL2 ACACA DSP HSPH1 DNAH2 PFKL CSMD2 NUP205 TUBB4B CDH20 DENND4B CCDC87 PHF14 NCR1	9.27e-08	736	165	17	29676528
Pubmed	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.	DPYSL2 DSP RPS3A PARK7 SPTAN1 HSPH1 PFKL OLA1 ITGB3 PAICS TUBB4B HPRT1 SCARB1 CD101 MVP	9.36e-08	565	165	15	20458337
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	FLNC DPYSL2 DSP MFHAS1 SPTAN1 HSPH1 CYP51A1 PAICS OSBPL2 SLC12A4 PRRC2C SCARB1 SLC12A7 AKAP1 GCN1	1.00e-07	568	165	15	37774976
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	FLNC DPYSL2 SPTAN1 HSPH1 PFKL ITGAM ITGB3 MYOF TUBB4B HPRT1 GCN1 G6PD	1.06e-07	344	165	12	30333137
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	EPRS1 FLNC DPYSL2 RELN SPTAN1 ITGB3 PAICS MET TUBB4B PRRC2C MVP G6PD	1.72e-07	360	165	12	33111431
Pubmed	FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy.	DPYSL2 DSG1 DSP PARK7 SPTAN1 HSPH1 PFKL PAICS HNRNPD HPRT1	3.37e-07	248	165	10	32963011
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	EPRS1 FLNC ACACA DSP PARK7 SPTAN1 HSPH1 OLA1 PAICS HNRNPD TXNRD1 MYOF TUBB4B HPRT1 ELAPOR1 GCN1 G6PD	3.38e-07	807	165	17	30575818
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	EPRS1 FLNC INTU DSP SPTAN1 HSPH1 DNAH2 NEB ADCY6 HNRNPD NUP205 CLCN4 SLC12A4 PRRC2C SMARCA1 CFAP74 PHF14 AATF KDR KIF5A OR10G8 BSN MED13	3.73e-07	1442	165	23	35575683
Pubmed	Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?	CYP2B6 ACACA PFKL CHRNA7 SLC6A3 SLC12A4 PIK3CG SCARB1 KDR	3.76e-07	192	165	9	20602615
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	EPRS1 CACNA1S FLNC DPYSL2 ACACA RPS3A SPTAN1 HSPH1 FKBP9 PFKL OLA1 PAICS HNRNPD NUP205 TXNRD1 TUBB4B HPRT1 MTR PCYT2 GCN1 MVP G6PD CRTAP	4.36e-07	1455	165	23	22863883
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	EPRS1 DPYSL2 PDE6C PDE6B RPS3A PARK7 SPTAN1 PFKL PAICS HNRNPD TUBB4B SYNJ1 HPRT1 G6PD	4.41e-07	552	165	14	36293380
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	EPRS1 DSG1 DSP RPS3A PARK7 SPTAN1 PAICS HNRNPD NUP205 TUBB4B CSF2RB PRRC2C HPRT1 GCN1 G6PD	4.66e-07	641	165	15	36057605
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	EPRS1 FLNC DPYSL2 DSG1 DSP RPS3A SPTAN1 PAICS HNRNPD MYOF TUBB4B GCN1	4.88e-07	397	165	12	21319273
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	EPRS1 FLNC DPYSL2 DSG1 DSP RPS3A SPTAN1 HSPH1 TXNDC12 MKS1 NUP205 TUBB4B B9D1 GCN1	5.70e-07	564	165	14	21565611
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	FLNC DPYSL2 ACACA DSG1 DSP MTHFD2 HSPH1 CYP51A1 ZNF185 PFKL OLA1 ITGAM PAICS HNRNPD NUP205 TXNRD1 MYOF TUBB4B AATF GCN1 MVP G6PD	5.92e-07	1367	165	22	32687490
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	FLNC DPYSL2 DSG1 DSP RPS3A PARK7 HSPH1 NEB PAICS HNRNPD TUBB4B AGO1 CLPB HPRT1 GCN1 MVP G6PD	6.27e-07	844	165	17	25963833
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	EPRS1 ACACA DSG1 DSP RPS3A PARK7 SPTAN1 HSPH1 PRSS56 PFKL OLA1 PAICS HNRNPD TXNDC12 TXNRD1 TUBB4B SLC16A3 PRRC2C HPRT1 MDC1 GCN1 G6PD	1.05e-06	1415	165	22	28515276
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	FRAS1 DSG1 TNC MET SCARB1 NUP210 TMX3 CRTAP	1.26e-06	164	165	8	32409323
Pubmed	PARK2 promotes mitochondrial pathway of apoptosis and antimicrotubule drugs chemosensitivity via degradation of phospho-BCL-2.	EPRS1 DSG1 DSP MTHFD2 RPS3A HSPH1 OLA1 PAICS TUBB4B GCN1	1.39e-06	290	165	10	32929329
Pubmed	Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3η as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability.	EPRS1 FLNC DPYSL2 PDE6C DSG1 DSP OLA1 SLC16A3 G6PD	1.41e-06	225	165	9	31478661
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	EPRS1 DPYSL2 DSG1 DSP RPS3A PARK7 HSPH1 PFKL OLA1 HNRNPD MYOF TUBB4B SMARCA1 GCN1 MVP G6PD	1.57e-06	803	165	16	36517590
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FLNC DPYSL2 ACACA DSG1 SPTAN1 HSPH1 PFKL OLA1 HNRNPD MYOF AGO1 UPF2 PRRC2C AATF GCN1	2.10e-06	724	165	15	36232890
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	EPRS1 DSG1 DSP RPS3A SPTAN1 HSPH1 ZNF185 PFKL PAICS HNRNPD NUP205 MYOF TUBB4B UPF2 PRRC2C MDC1 NUP210 SMARCA1 AATF MVP	2.39e-06	1257	165	20	36526897
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	EPRS1 ACACA DSG1 DSP MTHFD2 RPS3A PARK7 HSPH1 CYP51A1 PFKL PAICS HNRNPD NUP205 TUBB4B CLPB HPRT1 NUP210 MTR TMX3 GCN1	2.39e-06	1257	165	20	37317656
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	DSP RPS3A PARK7 SPTAN1 HSPH1 HNRNPD NUP205 TUBB4B HPRT1 MDC1 NUP210 GCN1	2.42e-06	463	165	12	34901782
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	ACACA DSG1 DSP RPS3A DNAH2 PAICS HNRNPD TUBB4B AGO1 POGLUT2	3.09e-06	317	165	10	30997501
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNC DPYSL2 ACACA DSP RPS3A SPTAN1 PAICS NUP205 PRRC2C MDC1 NUP210 AATF GCN1 MVP	3.15e-06	653	165	14	22586326
Pubmed	Defining the membrane proteome of NK cells.	EPRS1 CYP51A1 PFKL OLA1 PAICS NUP205 BTN3A3 CSGALNACT2 PIK3CG PRRC2C NUP210 KIF5A PLD1 AKAP1 GCN1 MVP MUL1 G6PD MED13	3.17e-06	1168	165	19	19946888
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	EPRS1 ACACA DSG1 DSP MTHFD2 RPS3A PARK7 PFKL HNRNPD TUBB4B PRRC2C MAPK7 GCN1 G6PD	3.27e-06	655	165	14	35819319
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	ACACA DSP SPTAN1 DNAH2 HNRNPD NUP205 MYOF TUBB4B SLC12A4 CLPB SLC16A3 MDC1 NUP210 AKAP1 G6PD	3.44e-06	754	165	15	35906200
Pubmed	The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection.	STAT4 PRDM1 NCR1	3.62e-06	7	165	3	24747678
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	EPRS1 MTHFD2 PARK7 SPTAN1 CYP51A1 FKBP9 PAICS HNRNPD TXNDC12 TXNRD1 MSRB2 MYOF SCARB1 TMX3 PCK2 CRTAP	3.71e-06	859	165	16	31536960
Pubmed	VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.	DPYSL2 RPS3A PARK7 HSPH1 OLA1 HNRNPD TXNRD1 TUBB4B HPRT1 G6PD	4.29e-06	329	165	10	35562734
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	EPRS1 ACACA DSP RPS3A CEP192 OLA1 HNRNPD TUBB4B PRRC2C GCN1	4.40e-06	330	165	10	32529326
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	EPRS1 FLNC DSP RPS3A SPTAN1 HSPH1 PFKL PAICS HNRNPD TUBB4B GCN1 MVP	4.69e-06	494	165	12	26831064
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FNBP1 EPRS1 ACACA DSP FOSL2 SPTAN1 REXO1 ADCY6 HNRNPD MYOF KMT2D MDC1 PHF14 AKAP1 MED13	4.72e-06	774	165	15	15302935
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	FLNC ACACA DSG1 DSP RPS3A HSPH1 PRSS56 CYP51A1 PAICS HNRNPD TXNDC12 NUP205 BUD23 TUBB4B MDC1 PHF14 AATF	5.27e-06	989	165	17	36424410
Pubmed	Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.	FNBP1 EPRS1 DSP RPS3A PARK7 HSPH1 PAICS HNRNPD NUP205 TUBB4B HPRT1	5.58e-06	418	165	11	32552912
Pubmed	Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly.	EPRS1 RPS3A MYOF TUBB4B MVP G6PD	5.64e-06	93	165	6	38245532
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	EPRS1 ACACA DSP SALL4 MYOF PRRC2C NUP210 GCN1	5.93e-06	202	165	8	33005030
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	EPRS1 HSPH1 L1CAM PAICS MYOF TUBB4B NUP210 GCN1 MVP G6PD PCK2	6.10e-06	422	165	11	27342126
Pubmed	BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.	EPRS1 FLNC DSP PAICS G6PD	6.49e-06	55	165	5	33067418
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	ACACA RPS3A PARK7 HNRNPD NUP205 BUD23 TUBB4B UPF2 HPRT1 SMARCA1 PCYT2 TBC1D23 GCN1 PCK2	7.42e-06	704	165	14	29955894
Pubmed	Physiological and pathophysiological characteristics of ataxin-3 isoforms.	EPRS1 ACACA DSG1 DSP RPS3A HSPH1 PAICS TUBB4B GCN1	8.61e-06	281	165	9	30455355
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	ACACA DSG1 DSP RPS3A PARK7 HSPH1 TUBB4B MDC1 GCN1 G6PD	8.75e-06	357	165	10	37059091
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	EPRS1 FLNC DPYSL2 ACACA DSP RPS3A PARK7 SPTAN1 HSPH1 PFKL PAICS HNRNPD TXNDC12 TUBB4B PRRC2C HPRT1 GCN1 G6PD	9.75e-06	1149	165	18	35446349
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	EPRS1 DPYSL2 RPS3A HSPH1 TXNRD1 TUBB4B PRRC2C	1.02e-05	156	165	7	32850835
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	EPRS1 FLNC MTHFD2 RPS3A HSPH1 PAICS HNRNPD TUBB4B PRRC2C HPRT1 NUP210 SMARCA1 MTR GCN1	1.03e-05	725	165	14	27025967
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EPRS1 DPYSL2 RELN RAP1GAP DSP SPTAN1 HSPH1 PAICS TUBB4B CLPB SYNJ1 RALBP1 USP32 KIF5A TBC1D23 PADI2 MVP MED13 CRTAP	1.22e-05	1285	165	19	35914814
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	RELN ADCY6 ADCY7	1.23e-05	10	165	3	16615126
Pubmed	FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.	EPRS1 RPS3A SPTAN1 HSPH1 CYP51A1 PAICS TUBB4B MTR	1.26e-05	224	165	8	28443643
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	EPRS1 DSG1 DSP MTHFD2 RPS3A SPTAN1 HSPH1 PFKL HNRNPD BUD23 NEDD9 TUBB4B SLC16A3 MDC1 AATF MVP	1.28e-05	949	165	16	36574265
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	EPRS1 FLNC DSG1 DSP RPS3A SPTAN1 HSPH1 PAICS HNRNPD TUBB4B PRRC2C HPRT1	1.40e-05	551	165	12	34728620
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	EPRS1 FLNC DSG1 DSP RPS3A SPTAN1 HSPH1 HNRNPD TUBB4B PRRC2C CCDC87 MVP	1.58e-05	558	165	12	27591049
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	EPRS1 MTHFD2 RPS3A SPTAN1 HSPH1 HNRNPD NUP205 TUBB4B HPRT1 GCN1	1.61e-05	383	165	10	29331416
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TNC CYP51A1 PFKL PAICS ZNRF3 RALBP1 HPRT1 PCYT2 AATF KIF5A MAPK7 MVP	1.64e-05	560	165	12	21653829
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	PARK7 SPTAN1 ZNF185 OLA1 PAICS TUBB4B SLC16A3 SYNJ1 CASKIN2 SCARB1 GCN1 PCDH1	1.79e-05	565	165	12	25468996
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	SHISA2 ADCY6 SLC6A8 MET SLC12A4 SLC16A3 CASKIN2 SCARB1 USP32 SLC12A7 PCDH1 PCDH18	1.92e-05	569	165	12	30639242
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	EPRS1 L1CAM PRSS56 CYP51A1 MYOF SLC16A3 SCARB1 PLD1 GCN1 PCK2	1.96e-05	392	165	10	33144569
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	EPRS1 HSPH1 CYP51A1 OLA1 PAICS NUP205 TUBB4B OSBPL2 CLPB HPRT1 MTR GCN1	1.98e-05	571	165	12	37167062
Pubmed	Genomic structure and promoter analysis of the mouse neutral ceramidase gene.	ASAH2 ASAH2B	2.24e-05	2	165	2	12435403
Pubmed	PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.	ITGAM PIK3CG	2.24e-05	2	165	2	17173040
Pubmed	Exchange of Cone for Rod Phosphodiesterase 6 Catalytic Subunits in Rod Photoreceptors Mimics in Part Features of Light Adaptation.	PDE6C PDE6B	2.24e-05	2	165	2	26085644
Pubmed	Anlotinib, a novel small molecular tyrosine kinase inhibitor, suppresses growth and metastasis via dual blockade of VEGFR2 and MET in osteosarcoma.	MET KDR	2.24e-05	2	165	2	30719715
Pubmed	Same origins of DNA replication function on the active and inactive human X chromosomes.	HPRT1 G6PD	2.24e-05	2	165	2	12616531
Pubmed	Nicotinic acetylcholine receptor alpha 7 regulates cAMP signal within lipid rafts.	ADCY6 CHRNA7	2.24e-05	2	165	2	12748066
Pubmed	A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer's disease.	ASAH2 ASAH2B	2.24e-05	2	165	2	17334805
Pubmed	Bi-Allelic Mutations in NUP205 and NUP210 Are Associated With Abnormal Cardiac Left-Right Patterning.	NUP205 NUP210	2.24e-05	2	165	2	31306055
Pubmed	The role of c-Met and VEGFR2 in glioblastoma resistance to bevacizumab.	MET KDR	2.24e-05	2	165	2	33727583
Pubmed	Pulmonary endothelial NEDD9 and the prothrombotic pathophenotype of acute respiratory distress syndrome due to SARS-CoV-2 infection.	ITGB3 NEDD9	2.24e-05	2	165	2	35599981
Pubmed	Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases.	ASAH2 ASAH2B	2.24e-05	2	165	2	10753931
Pubmed	Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis.	HPRT1 NUP210	2.24e-05	2	165	2	29736031
Pubmed	Myoferlin silencing inhibits VEGFR2-mediated proliferation of metastatic clear cell renal cell carcinoma.	MYOF KDR	2.24e-05	2	165	2	31477752
Pubmed	Attenuated expression of tenascin-C in ovalbumin-challenged STAT4-/- mice.	TNC STAT4	2.24e-05	2	165	2	21205293
Pubmed	Cone Phosphodiesterase-6γ' Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits.	PDE6C PDE6B	2.24e-05	2	165	2	30038560
Pubmed	A novel mouse model of creatine transporter deficiency.	SLC6A8 HPRT1	2.24e-05	2	165	2	25485098
Pubmed	Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection.	ASAH2 ASAH2B	2.24e-05	2	165	2	35354041
Pubmed	Deletion of the Creatine Transporter (Slc6a8) in Dopaminergic Neurons Leads to Hyperactivity in Mice.	SLC6A3 SLC6A8	2.24e-05	2	165	2	31520365
Pubmed	Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.	ASAH2 ASAH2B	2.24e-05	2	165	2	24659784
Pubmed	A Physical Interaction between the Dopamine Transporter and DJ-1 Facilitates Increased Dopamine Reuptake.	PARK7 SLC6A3	2.24e-05	2	165	2	26305376
Pubmed	Calcium dynamics change in degenerating cone photoreceptors.	PDE6C PDE6B	2.24e-05	2	165	2	27402880
Pubmed	Cav1.4 L-Type Calcium Channels Contribute to Calpain Activation in Degenerating Photoreceptors of rd1 Mice.	CACNA1F PDE6B	2.24e-05	2	165	2	27270916
Pubmed	Quantitative analysis of three-dimensional human mammary epithelial tissue architecture reveals a role for tenascin-C in regulating c-met function.	TNC MET	2.24e-05	2	165	2	20042668
Pubmed	Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury.	ASAH2 ASAH2B	2.24e-05	2	165	2	35151662
Pubmed	Identification of genetic drivers of plasma lipoprotein size in the Diversity Outbred mouse population.	ASAH2 ASAH2B	2.24e-05	2	165	2	37944753
Pubmed	A novel inhibitor of c-Met and VEGF receptor tyrosine kinases with a broad spectrum of in vivo antitumor activities.	MET KDR	2.24e-05	2	165	2	23548264
Pubmed	Role of neutral ceramidase in colon cancer.	ASAH2 ASAH2B	2.24e-05	2	165	2	27609772
Pubmed	Integrin β3 and its ligand regulate the expression of uPA through p38 MAPK in breast cancer.	TNC ITGB3	2.24e-05	2	165	2	21091771
Pubmed	Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney.	ASAH2 ASAH2B	2.24e-05	2	165	2	11328816
Pubmed	Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation.	ASAH2 ASAH2B	2.24e-05	2	165	2	19345744
Pubmed	Lactosylceramide contributes to mitochondrial dysfunction in diabetes.	ASAH2 ASAH2B	2.24e-05	2	165	2	26900161
Interaction	SH3GL3 interactions	ACACA DSP PARK7 SPTAN1 HSPH1 PAICS SYNJ1 CD101 MRPL32 G6PD	2.77e-07	145	162	10	int:SH3GL3
Interaction	LYN interactions	PIK3AP1 FNBP1 SDK2 DSG1 DSP RPS3A SPTAN1 SHISA2 NEDD9 SLC6A8 MET CSF2RB SLC12A4 CASKIN2 PIK3CG SCARB1 SMARCA1 PLD1 SLC12A7	5.55e-06	720	162	19	int:LYN
Interaction	H2BC9 interactions	EPRS1 FRAS1 DNAH10 DSG1 DSP NOA1 SPTAN1 NEB HNRNPD ADCY7 MDC1 KIF5A MAPK7 MVP	1.55e-05	446	162	14	int:H2BC9
Interaction	AAR2 interactions	EPRS1 INTU ACACA DSP RPS3A PARK7 HSPH1 PRSS56 PAICS HNRNPD TXNDC12 TUBB4B SLC16A3 HPRT1 KDR GCN1 G6PD	2.29e-05	657	162	17	int:AAR2
Interaction	ACE2 interactions	EPRS1 ACACA DSG1 DSP RPS3A PARK7 SPTAN1 PFKL PAICS HNRNPD CHRNA7 NUP205 MYOF TUBB4B BTN3A3 CSF2RB PRRC2C HPRT1 SCARB1 MDC1 GCN1 MVP G6PD	2.67e-05	1106	162	23	int:ACE2
GeneFamily	Ferlin family	MYOF FER1L4	6.02e-04	6	116	2	828
GeneFamily	Immunoglobulin like domain containing	SDK2 CILP2 CD101 KDR NCR1 IGSF21	1.54e-03	193	116	6	594
GeneFamily	Chloride voltage-gated channels	CLCN4 CLCN6	1.78e-03	10	116	2	302
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY6 ADCY7	1.78e-03	10	116	2	53
Coexpression	HARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN	SLC29A3 SDK2 RPS3A ZNF185 ITGAM ARHGAP6 CLCN4 KCNJ5 SCARB1 CD101 PLCB2 LOXL3 KIF5A ARRDC2 PADI2 PCDH1 CRTAP	4.68e-06	740	165	17	M41202
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN	DSP SPTAN1 ESRP1 SLC6A8 KMT2D AGO1 CASTOR1 RALBP1 ARRDC2	5.05e-06	199	165	9	M7319
Coexpression	HALLMARK_MTORC1_SIGNALING	EPRS1 ACACA MTHFD2 CYP51A1 PFKL NUP205 TXNRD1 HPRT1 G6PD	5.26e-06	200	165	9	M5924
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	FLNC CYP2B6 SDK2 FOSL2 MEX3D L1CAM RHBDL1 ADCY6 SLC6A8 MSRB2 ARHGAP6 MAST4 CLCN4 P2RX2 SCARB1 USP32 B9D1 POGLUT2	1.82e-05	909	165	18	M41018
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	RELN MFHAS1 MTHFD2 FOSL2 HSPH1 ADCY7 TXNRD1 SLC6A8 BTN3A3 OSBPL2 CSGALNACT2 CLCN6 UPF2 DCUN1D2 MAPK7 MMP13 SLC12A7	1.82e-05	822	165	17	M6782
Coexpression	CUI_DEVELOPING_HEART_TRABECULAR_ATRIAL_CARDIOMYOCYTE	EPRS1 FLNC FRAS1 RELN DSP SPTAN1 CYP51A1 AKAP1	1.86e-05	179	165	8	M39308
Coexpression	GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_DN	SLC29A3 FOSL2 RHBDL1 SHISA2 RGP1 REXO1 KMT2D	2.93e-05	139	165	7	M8948
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_DN	FNBP1 ADCY7 KMT2D CSF2RB MDC1 PCYT2 AATF SLC12A7	3.98e-05	199	165	8	M7711
Coexpression	GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN	DPYSL2 RELN PAICS PRDM1 PIK3CG HPRT1 MVP G6PD	4.12e-05	200	165	8	M4889
Coexpression	GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP	FOSL2 HSPH1 CYP51A1 PRDM1 MET CSF2RB SLC12A4 MRPL32	4.12e-05	200	165	8	M8638
Coexpression	GSE6875_WT_VS_FOXP3_KO_TREG_UP	PIK3AP1 ACACA SPTAN1 L1CAM ITGB3 STAT4 AGO1 PIK3CG	4.12e-05	200	165	8	M6803
Coexpression	NFE2L2.V2	PDE6B MTHFD2 L1CAM SHISA2 STAT4 TXNRD1 CD101 ELAPOR1 LOXL3 G6PD PCK2 CRTAP	4.48e-05	469	165	12	M2870
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 DSP HSPH1 NEDD9 ZNRF3 PRRC2C MTR MED13 ACSS3	4.59e-08	193	165	9	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC ZNF185 FKBP9 ETV4 CILP2 FKBP7 LOXL3 CDH11 CRTAP	5.97e-08	199	165	9	edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F FRAS1 RELN DNAH10 RGS22 SALL4 NEB KIF5A	4.46e-07	184	165	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F FRAS1 RELN DNAH10 RGS22 SALL4 NEB KIF5A	4.46e-07	184	165	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F FRAS1 RELN DNAH10 RGS22 SALL4 NEB KIF5A	4.46e-07	184	165	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SDK2 CHRNA5 NLRP6 MET KCNJ5 SLC12A7 IGSF21	5.98e-07	131	165	7	81efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 DSP HSPH1 NEDD9 ZNRF3 MTR MED13 ACSS3	6.15e-07	192	165	8	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2B6 ACACA ESRP1 PEBP4 MET MAST4 ELAPOR1	4.63e-06	178	165	7	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	CYP2B6 ACACA ESRP1 PEBP4 MET MAST4 ELAPOR1	5.96e-06	185	165	7	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2B6 ACACA ESRP1 PEBP4 MET MAST4 ELAPOR1	5.96e-06	185	165	7	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PIK3AP1 FOSL2 PNLDC1 ITGAM NEDD9 SLC16A3 NCR1	5.96e-06	185	165	7	25781cf68e693e97dc1885e2879ab24fa946b51e
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	CYP2B6 ACACA DSP ESRP1 MET MAST4 ELAPOR1	5.96e-06	185	165	7	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	CYP2B6 ACACA ESRP1 PEBP4 MET MAST4 ELAPOR1	6.40e-06	187	165	7	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 CYP2B6 DSP MET MAST4 ELAPOR1 KDR	7.10e-06	190	165	7	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA ESRP1 PEBP4 MET MAST4 ZNRF3 ACSS3	7.34e-06	191	165	7	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA ESRP1 PEBP4 MET MAST4 ZNRF3 ACSS3	7.34e-06	191	165	7	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	RAP1GAP ACACA PEBP4 MET MAST4 ZNRF3 ACSS3	7.60e-06	192	165	7	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	ACACA ESRP1 PEBP4 MET MAST4 ZNRF3 ACSS3	7.60e-06	192	165	7	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RAP1GAP ESRP1 PEBP4 MET MAST4 ZNRF3 ACSS3	7.60e-06	192	165	7	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 TNC PGM5 ARHGAP6 MYOF CDH11 ACSS3	7.60e-06	192	165	7	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	FOSL2 ITGAM ADCY7 STAT4 PRDM1 NCR1 G6PD	8.13e-06	194	165	7	335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell	COPD-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	MFHAS1 TNC MTHFD2 NOA1 KHDC4 MET MYOF	8.13e-06	194	165	7	8dcde77767b23e75360adb316cdccf56a00e3726
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ESRP1 MET MAST4 ZNRF3 RALBP1 MTR	8.69e-06	196	165	7	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	PIK3AP1 FOSL2 ITGAM ADCY7 PRDM1 NCR1 G6PD	8.69e-06	196	165	7	07b557b8530c19ca5b31ad2eac00c36ef1939266
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	INTU SDK2 TNC MYOF KIF5A BSN CDH11	8.98e-06	197	165	7	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 FNBP1 ITGAM ADCY7 STAT4 PIK3CG PLCB2	8.98e-06	197	165	7	61ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PIK3AP1 SALL4 PNLDC1 PLCB2 LOXL3 KIF5A IGSF21	8.98e-06	197	165	7	0a404b4494a2246d5a92299235056f0fda4d2b48
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP TNC TXNRD1 SLC6A8 MET MAST4 MMP13	9.28e-06	198	165	7	77517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 CYP2B6 DSP MET MAST4 ELAPOR1 KDR	9.28e-06	198	165	7	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 CYP2B6 DSP MET MAST4 ELAPOR1 KDR	9.28e-06	198	165	7	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 CHRNA7 MET ELAPOR1 KDR MMP13 CDH11	9.91e-06	200	165	7	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPTAN1 ARHGAP6 CASKIN2 SCARB1 KDR ARRDC2 PCDH1	9.91e-06	200	165	7	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGAM ADCY7 PRDM1 SLC6A3 CLCN4 PADI2	1.98e-05	149	165	6	a464c0fd54e3c9e1d40d95b49489cb9371dd7c24
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 ADCY7 STAT4 PIK3CG NCR1 SLC12A7	2.56e-05	156	165	6	a09e3aefe78d63ad5428ad48c6f83e547eb819f6
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 ADCY7 STAT4 PIK3CG NCR1 SLC12A7	2.56e-05	156	165	6	39aa3adbee9f04cdc0055487d393edfa515e062b
ToppCell	facs-Marrow-KLS-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEX3D PNLDC1 KLHL29 CFAP74 NCR1 MUL1	2.66e-05	157	165	6	5d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCell	facs-Marrow-KLS-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEX3D PNLDC1 KLHL29 CFAP74 NCR1 MUL1	2.66e-05	157	165	6	ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCell	Club_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	CYP2B6 DSP MET ELAPOR1 KDR BSN	3.39e-05	164	165	6	4e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	TNC SHISA2 SALL4 CILP2 BSN MMP13	3.39e-05	164	165	6	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	RAP1GAP MFHAS1 SHISA2 ITGB3 KCNJ5 SMARCA1	3.63e-05	166	165	6	8d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 CYP2B6 ACACA MET MAST4 ELAPOR1	4.15e-05	170	165	6	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2B6 FREM3 MET MAST4 ELAPOR1 KDR	4.28e-05	171	165	6	fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2B6 FREM3 MET MAST4 ELAPOR1 KDR	4.28e-05	171	165	6	4347e6f62c04ea43299893ad4b79719049009a56
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2B6 FREM3 MET MAST4 ELAPOR1 KDR	4.28e-05	171	165	6	d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2B6 FREM3 MET MAST4 ELAPOR1 KDR	4.28e-05	171	165	6	d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells-mDC\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MTHFD2 CDH20 PIK3CG CD101 PLCB2 PADI2	4.43e-05	172	165	6	cc0e2a45fa74ee19e41612c3615729462474003a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN CSMD2 ITGB3 MET CDH20 MMP13	4.57e-05	173	165	6	2e35bf2b5534a289d93a09faae660f665c131062
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP95 INTU PDE6C DNAH10 DNAH2 B9D1	4.57e-05	173	165	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	droplet-Tongue-Unstain-18m-Myeloid\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S DNAH2 STAT4 CSF2RB P2RX2 PIK3CG	4.72e-05	174	165	6	f2eb0199f59e1e2f46da344c05289876bd254fa3
ToppCell	droplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S DNAH2 STAT4 CSF2RB P2RX2 PIK3CG	4.72e-05	174	165	6	9019011eb8d9b7a95804fc11434f0fd42418103a
ToppCell	Adult-Epithelial-basal_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 SDK2 DSP MET CILP2 ELAPOR1	4.72e-05	174	165	6	a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SDK2 TXNRD1 MAST4 KCNJ5 BSN	4.72e-05	174	165	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	droplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S DNAH2 STAT4 CSF2RB P2RX2 PIK3CG	4.72e-05	174	165	6	deafbd0c2523afe09cc42f8c7b33945f3f5c00b4
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4\|TCGA-Lung / Sample_Type by Project: Shred V9	ITGB3 MET MYOF CILP2 KDR CDH11	5.03e-05	176	165	6	0923b01137d6f9956ca815b41102c81e82624065
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	FRAS1 CYP2B6 SALL4 PAICS MET ELAPOR1	5.19e-05	177	165	6	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP95 SDK2 RGS22 DNAH2 NLRP6 CFAP74	5.36e-05	178	165	6	6178706db4a855d72abc156537604d575624df56
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S CFAP95 DNAH10 RGS22 CFAP74 ACSS3	5.36e-05	178	165	6	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HSPH1 FKBP9 SHISA2 SALL4 KDR CDH11	5.36e-05	178	165	6	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP95 SDK2 RGS22 DNAH2 NLRP6 CFAP74	5.36e-05	178	165	6	f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S CFAP95 DNAH10 RGS22 CFAP74 ACSS3	5.36e-05	178	165	6	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SDK2 CHRNA7 STAT4 MET PCDH18	5.52e-05	179	165	6	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASAH2 MEX3D ITGB3 MAST4 CASKIN2 KDR	5.52e-05	179	165	6	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	18-Airway-Epithelial-Submucosal_gland_basal\|Airway / Age, Tissue, Lineage and Cell class	ETV4 SHISA2 ITGB3 SCARB1 ELAPOR1 PADI2	5.88e-05	181	165	6	33938e6521712058312879f84f4ae381c2bfc379
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CRISP2 ITGAM PIK3CG CD101 G6PD ACSS3	6.06e-05	182	165	6	52eac2f892ea7f26731e0b21c578fd2665a1657a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S CFAP95 RGS22 ZNF185 CCDC87 ACSS3	6.06e-05	182	165	6	587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S CFAP95 RGS22 ZNF185 CCDC87 ACSS3	6.06e-05	182	165	6	adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCell	droplet-Tongue-nan-24m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 DNAH2 STAT4 CSF2RB P2RX2 PIK3CG	6.06e-05	182	165	6	0f06309318c064f0ebdb12a46226b90032290137
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SDK2 L1CAM CILP2 CLCN6 LOXL3 IGSF21	6.06e-05	182	165	6	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA PEBP4 MET MAST4 ZNRF3 ACSS3	6.24e-05	183	165	6	6847c1252d6bb105524f812658112517fd351eab
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 TNC P2RX2 KCNJ5 KDR PCDH18	6.24e-05	183	165	6	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1S MTHFD2 ADCY6 STAT4 CSF2RB MVP	6.63e-05	185	165	6	19fa853f6f746ccf232a343b3c9c7a5e55800409
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CSMD2 ITGB3 MET CDH20 PIK3CG ELAPOR1	6.63e-05	185	165	6	5a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell	droplet-Bladder-nan-24m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DNAH2 ITGB3 KLHL29 SCARB1 KIF5A	6.63e-05	185	165	6	90caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Otof-Lmo2_(eccentric_SPN,_dSPN-like_markers)\|Striatum / BrainAtlas - Mouse McCarroll V32	PNLDC1 FREM3 STAT4 PEBP4	6.78e-05	59	165	4	e6cbbe1a4961066cae8f8c03a838f37e60a5391a
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Otof-Lmo2_(eccentric_SPN,_dSPN-like_markers)-\|Striatum / BrainAtlas - Mouse McCarroll V32	PNLDC1 FREM3 STAT4 PEBP4	6.78e-05	59	165	4	dbb61f03be7d2c7fa7d32c743fcff2dc91ae0d75
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 DSP MET MAST4 ELAPOR1 KDR	7.04e-05	187	165	6	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNC SALL4 CSMD2 ARHGAP6 PCDH18 CDH11	7.25e-05	188	165	6	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	RAP1GAP TNC SHISA2 PEBP4 MET MAST4	7.25e-05	188	165	6	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 TNC ARHGAP6 MYOF CDH11 ACSS3	7.46e-05	189	165	6	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	SDK2 DSP TNC MET MAST4 MMP13	7.68e-05	190	165	6	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MFHAS1 ESRP1 NEDD9 MET ARHGAP6 MYOF	7.68e-05	190	165	6	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MFHAS1 ESRP1 NEDD9 MET ARHGAP6 MYOF	7.68e-05	190	165	6	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	MFHAS1 MET MYOF MAST4 CSF2RB CDH11	7.68e-05	190	165	6	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 ITGAM ADCY7 PLCB2 LOXL3 IGSF21	7.68e-05	190	165	6	788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PIK3AP1 ITGAM PRDM1 CSF2RB PIK3CG KCNJ5	7.68e-05	190	165	6	912aa106581d1ed7e147c92f9a367e8e6b04052b
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-C1ql3_(Nucleus_of_the_lateral_olfactory_tract_(LOT))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	RHBDL1 STAT4 MET CILP2	7.73e-05	61	165	4	a9f5cbbe5683f2574130ffe8d375d693b9aa8f2d
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-C1ql3_(Nucleus_of_the_lateral_olfactory_tract_(LOT))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	RHBDL1 STAT4 MET CILP2	7.73e-05	61	165	4	3797e1e122818211664847bb54730034af61430e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RAP1GAP ESRP1 MET MAST4 ZNRF3 ACSS3	7.91e-05	191	165	6	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 ITGAM ADCY7 PLCB2 LOXL3 IGSF21	7.91e-05	191	165	6	baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN PGM5 CASKIN2 SCARB1 KDR CA7	7.91e-05	191	165	6	79b399496bd7322a1d53c43378f48695fd09a5d9
ToppCell	facs-Trachea-24m-Endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN PGM5 CASKIN2 SCARB1 KDR CA7	7.91e-05	191	165	6	9c6d5d045781c6506ae80e318427ef1e0d87f45c
ToppCell	facs-Thymus-Epithelium-3m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP9 CSF2RB SCARB1 KDR PCDH1 CA7	7.91e-05	191	165	6	d2311a5b0cf186839000f9f272b6fbc2270ddb44
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP ESRP1 ETV4 ZNRF3 ELAPOR1 AKAP1	7.91e-05	191	165	6	a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCell	facs-Thymus-Epithelium-3m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP9 CSF2RB SCARB1 KDR PCDH1 CA7	7.91e-05	191	165	6	6676ef9aeb890668cb69e67865404061b8467c25
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN PGM5 CASKIN2 SCARB1 KDR CA7	7.91e-05	191	165	6	1b1e943709d0c3283a980c7c965ef1f110506a29
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	ACACA ESRP1 PEBP4 MET MAST4 ZNRF3	7.91e-05	191	165	6	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	wk_15-18-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FLNC RELN DSP PGM5 MET KDR	7.91e-05	191	165	6	d25ac3206fe205a100cfee26431ff32c14c1938f
ToppCell	facs-Thymus-Epithelium-3m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKBP9 CSF2RB SCARB1 KDR PCDH1 CA7	7.91e-05	191	165	6	a157cee0fbc9dce64308128c3578e7327fa178b7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 ITGAM ADCY7 PIK3CG PLCB2 IGSF21	8.14e-05	192	165	6	86d792682ba51696f503c79625dd20f87bcf651f
ToppCell	normal_Lung-Epithelial_cells-Ciliated\|normal_Lung / Location, Cell class and cell subclass	CFAP95 DNAH10 RGS22 DNAH2 B9D1 CFAP74	8.14e-05	192	165	6	097a13121820ab4e5cd2365600efccf5ea4ce8c3
Drug	ethanol	CACNA1F CYP2B6 SLC29A3 SPTAN1 L1CAM PFKL ITGAM ADCY6 ADCY7 CHRNA7 SLC6A3 CSF2RB PIK3CG MTR KDR PLCB2 PLD1 MAPK7 G6PD ACSS3 CA7	6.15e-07	837	163	21	CID000000702
Drug	serotonin	FOSL2 PFKL ITGB3 ADCY6 ADCY7 CHRNA7 BUD23 SLC6A3 CLCN4 CLCN6 P2RX2 KCNJ5 PLCB2 LOXL3 PLD1 MAPK7	2.50e-06	554	163	16	CID000005202
Drug	H2O2	EPRS1 CRISP2 PARK7 CYP51A1 ITGAM ADCY6 ADCY7 SLC6A3 MSRB2 MET CLCN4 SLC12A4 CLCN6 CLPB PIK3CG HPRT1 SCARB1 KDR PLCB2 LOXL3 PLD1 MAPK7 G6PD CDH11	3.89e-06	1183	163	24	CID000000784
Drug	noradrealine	CACNA1F CACNA1S ACACA HSPH1 ADCY6 ADCY7 SLC6A3 SLC16A3 P2RX2 PIK3CG PLCB2 LOXL3 PLD1 MAPK7 BSN MMP13	4.02e-06	575	163	16	CID000000951
Drug	furosemide	PAICS ADCY6 ADCY7 NLRP6 SLC6A3 CLCN4 SLC12A4 CLCN6 MTR SLC12A7 CA7	4.46e-06	272	163	11	CID000003440
Drug	meperidine	CACNA1S RELN CYP2B6 PARK7 SLC6A3 LOXL3	5.95e-06	63	163	6	CID000004058
Drug	Chelidonine monohydrate (+) [476-32-4]; Down 200; 10.8uM; HL60; HG-U133A	EPRS1 DPYSL2 ACACA HNRNPD TUBB4B SCARB1 CD101 AKAP1 PCK2	6.50e-06	181	163	9	1786_DN
Drug	amifostine	TP53I3 ADCY6 ADCY7 RALBP1 HPRT1 ALPG	7.15e-06	65	163	6	CID000002141
Drug	quinoline	MTHFD2 OLA1 ITGB3 PAICS HNRNPD MET	9.31e-06	68	163	6	ctd:C037219
Drug	Bepridil hydrochloride [74764-40-2]; Up 200; 10uM; MCF7; HT_HG-U133A	CRISP2 FOSL2 SPTAN1 PRDM1 KMT2D SLC16A3 SYNJ1 KCNJ5 PLD1	9.62e-06	190	163	9	5674_UP
Drug	Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A	CRISP2 ACACA FOSL2 KLHL29 MYOF CLCN6 CLPB MAPK7 MMP13	1.34e-05	198	163	9	2057_UP
Drug	PHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A	PDE6B CPEB3 STAT4 KLHL29 MET CSF2RB KCNJ5 KIF5A MAPK7	1.34e-05	198	163	9	4333_UP
Drug	MK-886; Up 200; 1uM; MCF7; HG-U133A	FRAS1 CYP2B6 FOSL2 L1CAM CLCN4 SLC12A4 CASKIN2 KCNJ5 CCDC87	1.34e-05	198	163	9	264_UP
Drug	6-OHDA	PARK7 ADCY6 ADCY7 SLC6A3 HPRT1 LOXL3 PLD1 MAPK7 BSN MUL1	1.60e-05	255	163	10	CID000004624
Drug	glutamate	CACNA1F EPRS1 CACNA1S RELN TNC PFKL PAICS ADCY6 ADCY7 CHRNA7 SLC6A3 CLCN4 CLCN6 P2RX2 MTR PLCB2 PLD1 BSN G6PD PCK2	1.90e-05	962	163	20	CID000000611
Drug	manganese-ATP	PFKL ADCY6 ADCY7 PCK2	2.85e-05	25	163	4	CID000124341
Drug	Curcumin	RELN ACACA TNC FOSL2 ITGAM ITGB3 HNRNPD STAT4 TXNRD1 CSF2RB CLCN6 HPRT1 SCARB1 AATF KDR MMP13 G6PD CDH11	4.02e-05	850	163	18	ctd:D003474
Drug	papaverine	CACNA1F CACNA1S PDE6C PDE6B ADCY6 ADCY7 PLCB2 PLD1	4.08e-05	176	163	8	CID000004680
Drug	INT-formazan	INTU G6PD	5.09e-05	2	163	2	CID000111334
Drug	spiromesifen	ACACA BSN	5.09e-05	2	163	2	CID009907412
Drug	((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy)acetic acid	SLC12A4 SLC12A7	5.09e-05	2	163	2	ctd:C095651
Drug	2,3-bis(3'-hydroxybenzyl)butyrolactone	FNBP1 L1CAM SHISA2 SALL4 PFKL PAICS NEDD9 TUBB4B MAST4 OSBPL2 SLC12A4 PRRC2C HPRT1 SCARB1 MDC1 NUP210 KDR MVP PCK2	6.11e-05	961	163	19	ctd:C029497
Drug	magnesium	CACNA1S DPYSL2 DNAH10 TNC MTHFD2 PFKL ITGAM ITGB3 PAICS ADCY6 ADCY7 TUBB4B CLPB KCNJ5 HPRT1 MTR AATF PLCB2 PLD1 MMP13 G6PD PCK2 ALPG	7.32e-05	1325	163	23	CID000000888
Drug	butein; Up 200; 10uM; MCF7; HG-U133A	CACNA1S FOSL2 RGP1 PRRC2C B9D1 CFAP74 PLD1 PADI2	8.10e-05	194	163	8	607_UP
Drug	muscarine	ADCY6 ADCY7 CHRNA7 KCNJ5 PLCB2 PLD1 BSN	8.19e-05	144	163	7	CID000009308
Drug	1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one	FLNC TNC FKBP9 TXNRD1 MYOF SLC12A4 CASKIN2 KIF5A SLC12A7 PCK2 CRTAP	8.20e-05	373	163	11	ctd:C540355
Drug	Isoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A	FNBP1 SLC29A3 MEX3D MKS1 MAST4 NUP210 MAPK7 SLC12A7	8.70e-05	196	163	8	2056_DN
Drug	Hesperetin [520-33-2]; Down 200; 13.2uM; HL60; HG-U133A	MFHAS1 ITGAM NUP205 MYOF CLPB PLD1 AKAP1 MUL1	8.70e-05	196	163	8	2031_DN
Drug	PHA-00745360 [351320-33-7]; Up 200; 10uM; MCF7; HT_HG-U133A	FRAS1 L1CAM PAICS SLC6A3 SMARCA1 PLD1 MAPK7 MMP13	8.70e-05	196	163	8	3907_UP
Drug	Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	ITGB3 ADCY6 CLCN4 SLC16A3 KCNJ5 PLCB2 MMP13 PCDH1	8.70e-05	196	163	8	4415_UP
Drug	Nicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A	RAP1GAP ADCY6 MYOF OSBPL2 DCUN1D2 CASKIN2 B9D1 G6PD	8.70e-05	196	163	8	2058_DN
Drug	Maprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; PC3; HT_HG-U133A	ADCY6 CDH20 CLCN4 CLCN6 SYNJ1 KCNJ5 SCARB1 PLD1	8.70e-05	196	163	8	6676_UP
Drug	prinomastat	TNC ITGAM KDR MMP13	8.81e-05	33	163	4	CID000466151
Drug	Moroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; PC3; HG-U133A	SLC29A3 ACACA MET CLPB SLC16A3 SMARCA1 B9D1 CFAP74	9.01e-05	197	163	8	1944_DN
Drug	Benfotiamine [22457-89-2]; Up 200; 8.6uM; HL60; HT_HG-U133A	FRAS1 CPEB3 ADCY6 MET MYOF CLCN4 KCNJ5 PLD1	9.01e-05	197	163	8	2177_UP
Drug	Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A	FOSL2 SPTAN1 NEDD9 SLC6A8 MET CASKIN2 B9D1 MVP	9.01e-05	197	163	8	4974_DN
Drug	L-adrenaline	CACNA1S ACACA ITGB3 ADCY6 ADCY7 CLCN4 CLCN6 PLCB2 LOXL3 MAPK7 G6PD PCK2	9.30e-05	446	163	12	CID000000838
Drug	(S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	RELN PDE6B ITGB3 ADCY6 BTN3A3 SYNJ1 KCNJ5 CDH11	9.34e-05	198	163	8	3523_UP
Drug	aspartate	MTHFD2 FKBP9 PFKL PAICS CLCN4 SLC12A4 CLCN6 KCNJ5 FKBP7 SLC12A7 G6PD PCK2 CRTAP	9.54e-05	518	163	13	CID000000424
Drug	Leucomisine [17946-87-1]; Up 200; 16.2uM; PC3; HT_HG-U133A	SLC29A3 RAP1GAP SLC6A8 ARHGAP6 BTN3A3 MAST4 CLCN6 MAPK7	9.67e-05	199	163	8	7125_UP
Drug	Chlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	TNC SPTAN1 PFKL ITGB3 BTN3A3 CASKIN2 PHF14 MAPK7	9.67e-05	199	163	8	3198_UP
Drug	Prednicarbate [73771-04-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A	CYP2B6 PDE6C FOSL2 PAICS ADCY7 CLCN4 CLCN6 NUP210	9.67e-05	199	163	8	5544_UP
Drug	FK-506; Down 200; 1uM; MCF7; HG-U133A	CYP2B6 RGP1 RALBP1 KCNJ5 ELAPOR1 SMARCA1 B9D1 NCR1	9.67e-05	199	163	8	284_DN
Drug	didodecyldimethylammonium bromide	INTU CYP2B6 CYP51A1	9.77e-05	13	163	3	CID000018669
Drug	Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A	FLNC PDE6B TNC FOSL2 ITGB3 MYOF BTN3A3 KCNJ5	1.00e-04	200	163	8	3167_UP
Drug	Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	CPEB3 STAT4 PRDM1 SLC6A3 MYOF KCNJ5 CD101 PLD1	1.00e-04	200	163	8	3840_UP
Drug	Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; HL60; HT_HG-U133A	TP53I3 ITGB3 ADCY6 MET SYNJ1 KCNJ5 B9D1 KIF5A	1.00e-04	200	163	8	2434_UP
Drug	Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A	PDE6B CPEB3 STAT4 KCNJ5 SMARCA1 B9D1 PHF14 MMP13	1.00e-04	200	163	8	3833_UP
Drug	AC1Q4Y39	SLC29A3 ADCY6 ADCY7 KCNJ5 PLD1	1.03e-04	65	163	5	CID000004402
Drug	endrine	CYP2B6 ADCY6 ADCY7 CLCN4 CLCN6 AATF	1.16e-04	106	163	6	CID000003048
Disease	Severe dermatitis, multiple allergies, metabolic wasting syndrome	DSG1 DSP	2.96e-05	2	161	2	C3809719
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	CYP2B6 CHRNA5 SLC6A3	3.38e-05	12	161	3	C1861063
Disease	high grade glioma (biomarker_via_orthology)	TNC SLC6A3 MET	6.91e-05	15	161	3	DOID:3070 (biomarker_via_orthology)
Disease	autistic disorder (is_implicated_in)	RELN MET PIK3CG MTR	8.13e-05	42	161	4	DOID:12849 (is_implicated_in)
Disease	Striate palmoplantar keratoderma	DSG1 DSP	8.84e-05	3	161	2	C4707237
Disease	bipolar disorder (is_marker_for)	RELN RAP1GAP L1CAM	1.45e-04	19	161	3	DOID:3312 (is_marker_for)
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1F CACNA1S	1.76e-04	4	161	2	DOID:0060173 (implicated_via_orthology)
Disease	Gilles de la Tourette syndrome (implicated_via_orthology)	SLC6A3 MET	1.76e-04	4	161	2	DOID:11119 (implicated_via_orthology)
Disease	sarcoma (is_marker_for)	MET KDR	2.93e-04	5	161	2	DOID:1115 (is_marker_for)
Disease	hepatocellular carcinoma (biomarker_via_orthology)	MTHFD2 HNRNPD MET HPRT1 G6PD	3.22e-04	108	161	5	DOID:684 (biomarker_via_orthology)
Disease	nicotine dependence (is_implicated_in)	CHRNA5 SLC6A3	4.37e-04	6	161	2	DOID:0050742 (is_implicated_in)
Disease	early-onset Parkinson's disease (implicated_via_orthology)	PARK7 SYNJ1	4.37e-04	6	161	2	DOID:0060894 (implicated_via_orthology)
Disease	Epilepsy, Generalized	CHRNA7 CLPB	4.37e-04	6	161	2	C0014548
Disease	Mental Depression	DPYSL2 RELN SLC29A3 CSMD2 ADCY7 SLC6A3 MTR	5.11e-04	254	161	7	C0011570
Disease	Autistic Disorder	RELN ITGB3 CHRNA7 SLC6A8 MET AGO1 PIK3CG	6.00e-04	261	161	7	C0004352
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	MYOF FER1L4	6.10e-04	7	161	2	DOID:11724 (implicated_via_orthology)
Disease	Alcoholic Intoxication, Chronic	DPYSL2 CYP2B6 ADCY7 CHRNA5 SLC6A3 AGO1 CDH11	7.01e-04	268	161	7	C0001973
Disease	hypokalemic periodic paralysis (implicated_via_orthology)	CACNA1S TUBB4B	8.11e-04	8	161	2	DOID:14452 (implicated_via_orthology)
Disease	Meckel syndrome (implicated_via_orthology)	MKS1 B9D1	8.11e-04	8	161	2	DOID:0050778 (implicated_via_orthology)
Disease	Nonsyndromic Deafness	TNC MET OSBPL2 P2RX2	1.02e-03	81	161	4	C3711374
Disease	Depressive disorder	DPYSL2 RELN SLC29A3 CSMD2 ADCY7 SLC6A3 MTR	1.09e-03	289	161	7	C0011581
Disease	Schizophrenia	CACNA1F RELN CSMD2 ITGAM ITGB3 ADCY7 CHRNA5 CHRNA7 SLC6A3 MET CSF2RB MTR KDR	1.16e-03	883	161	13	C0036341
Disease	obesity (implicated_via_orthology)	SDK2 DNAH10 ETV4 STAT4 PLCB2 MED13	1.20e-03	215	161	6	DOID:9970 (implicated_via_orthology)
Disease	Meckel-Gruber syndrome	MKS1 B9D1	1.29e-03	10	161	2	cv:C0265215
Disease	Microphthalmos	PRSS56 KMT2D	1.58e-03	11	161	2	C0026010
Disease	pars orbitalis volume measurement	CFAP95 ACSS3	1.58e-03	11	161	2	EFO_0010320
Disease	Night blindness, congenital stationary, type 1	CACNA1F PDE6B	1.88e-03	12	161	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	CACNA1F PDE6B	1.88e-03	12	161	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	CACNA1F PDE6B	1.88e-03	12	161	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	CACNA1F PDE6B	1.88e-03	12	161	2	C1850362
Disease	X-Linked Csnb	CACNA1F PDE6B	1.88e-03	12	161	2	C3711543
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	CACNA1F PDE6B	1.88e-03	12	161	2	C1848172
Disease	Congenital myopathy (disorder)	CACNA1S NEB	1.88e-03	12	161	2	C0270960
Disease	esophagus squamous cell carcinoma (is_implicated_in)	CHRNA5 CHRNA7 KMT2D	1.91e-03	45	161	3	DOID:3748 (is_implicated_in)
Disease	cholangiocarcinoma (biomarker_via_orthology)	TNC MET	2.22e-03	13	161	2	DOID:4947 (biomarker_via_orthology)
Disease	Cone-rod synaptic disorder, congenital nonprogressive	CACNA1F PDE6B	2.22e-03	13	161	2	C4041558
Disease	Sjogren's Syndrome	STAT4 PRDM1	2.22e-03	13	161	2	C1527336
Disease	Sicca Syndrome	STAT4 PRDM1	2.22e-03	13	161	2	C0086981
Disease	status epilepticus (biomarker_via_orthology)	DPYSL2 RELN SLC6A8 OSBPL2	2.23e-03	100	161	4	DOID:1824 (biomarker_via_orthology)
Disease	Malignant neoplasm of breast	RAP1GAP NOA1 SPTAN1 TP53I3 ETV4 OLA1 STAT4 SLC6A3 KMT2D CDH20 SLC16A3 ELAPOR1 MTR KDR	2.34e-03	1074	161	14	C0006142
Disease	brain ischemia (biomarker_via_orthology)	DPYSL2 ITGAM CSF2RB AKAP1	2.40e-03	102	161	4	DOID:2316 (biomarker_via_orthology)
Disease	lung non-small cell carcinoma (is_marker_for)	FOSL2 L1CAM ITGB3 MET KDR	2.40e-03	169	161	5	DOID:3908 (is_marker_for)
Disease	ulcerative colitis	PARK7 ITLN2 ADCY7 STAT4 PRDM1 NUP210 BSN	2.51e-03	335	161	7	EFO_0000729
Disease	Tobacco Dependence	CHRNA5 CHRNA7	2.58e-03	14	161	2	C0040332
Disease	Spastic Paraplegia, Hereditary	L1CAM KIF5A	2.58e-03	14	161	2	C0037773
Disease	Nicotine Dependence	CHRNA5 CHRNA7	2.58e-03	14	161	2	C0028043
Disease	Nicotine Use Disorder	CHRNA5 CHRNA7	2.58e-03	14	161	2	C0376384
Disease	Meckel-Gruber syndrome	MKS1 B9D1	2.97e-03	15	161	2	C0265215
Disease	ovarian carcinoma (is_implicated_in)	L1CAM MMP13	2.97e-03	15	161	2	DOID:4001 (is_implicated_in)
Disease	Lymphoma, Follicular, Grade 2	KMT2D MTR	2.97e-03	15	161	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	KMT2D MTR	2.97e-03	15	161	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	KMT2D MTR	2.97e-03	15	161	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	KMT2D MTR	2.97e-03	15	161	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	KMT2D MTR	2.97e-03	15	161	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	KMT2D MTR	2.97e-03	15	161	2	C0079758
Disease	inflammatory bowel disease	FOSL2 PARK7 ITLN2 ADCY7 STAT4 PRDM1 CSF2RB BSN	3.36e-03	449	161	8	EFO_0003767
Disease	Diffuse Large B-Cell Lymphoma	PRDM1 KMT2D PIK3CG	3.40e-03	55	161	3	C0079744
Disease	Night blindness, congenital stationary	CACNA1F PDE6B	3.81e-03	17	161	2	C0339535
Disease	Polydactyly	FRAS1 SALL4 MKS1 B9D1	3.93e-03	117	161	4	C0152427
Disease	Libman-Sacks Disease	ITGAM STAT4 PRDM1	3.95e-03	58	161	3	C0242380
Disease	aspartate aminotransferase measurement	PIK3AP1 CACNA1S MFHAS1 FOSL2 DNAH2 CILP2 CDH20 CLCN4 SCARB1 FKBP7 IGSF21 GCN1	4.12e-03	904	161	12	EFO_0004736
Disease	Child Behaviour Checklist assessment	PDE6C PEBP4	4.27e-03	18	161	2	EFO_0005661
Disease	Meckel syndrome type 1	MKS1 B9D1	4.27e-03	18	161	2	C3714506
Disease	Bipolar Disorder	DPYSL2 RELN PFKL ITGAM CHRNA7 SLC6A3 MTR G6PD	4.82e-03	477	161	8	C0005586
Disease	oral squamous cell carcinoma (is_marker_for)	FOSL2 MET KMT2D	4.98e-03	63	161	3	DOID:0050866 (is_marker_for)
Disease	sucrose liking measurement	RELN CDH20	5.27e-03	20	161	2	EFO_0010157
Disease	myelodysplastic syndrome (is_marker_for)	RAP1GAP ITGB3	5.27e-03	20	161	2	DOID:0050908 (is_marker_for)
Disease	Lymphoma, Follicular	KMT2D MTR	5.27e-03	20	161	2	C0024301

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGPPELFYDETEARK	BUD23	11	O43709
GYPVVPAEKRSSGER	AKAP1	181	Q92667
KYGDVFTVHLGPRPV	CYP2B6	61	P20813
EPPRKVGIFLDYETG	BTN3A3	456	O00478
EPAVPSNGVKTGERY	CSMD2	1911	Q7Z408
FSVPVGEIKPQGVYD	NEDD9	201	Q14511
FDIYREVGGEPVPVT	CASTOR1	141	Q8WTX7
PVVAGVIGARKPQYD	ADCY6	1091	O43306
GDVLQPAKPEYRVGE	ASAH2B	41	P0C7U1
PGKTPVYAEVKRVGD	AGO1	521	Q9UL18
FKSPEYPEGRDIIVI	ACACA	1666	Q13085
VDDIPDRPAGVGVYT	CLCN4	426	P51793
IFGPDGSRIPYIEQV	DPPA5	36	A6NC42
PVIAGVIGARKPQYD	ADCY7	996	P51828
ELIFGEPVIFKGRPY	CCDC87	791	Q9NVE4
PAKVEFGVYESGPRK	PIK3AP1	686	Q6ZUJ8
FGVYESGPRKSVIPP	PIK3AP1	691	Q6ZUJ8
DEILDFVYGVGPKSP	CRISP2	116	P16562
DRKGYTPGEVIPVFA	ARRDC2	191	Q8TBH0
VSEYPGVKTVRFPDG	CHRNA7	91	P36544
KEGILFVTYPDGRPT	ESRP1	356	Q6NXG1
IKQEGVGAFREGPPY	ETV4	321	P43268
EEISPTKFPGLYRTG	RALBP1	31	Q15311
YVKEVAKPSPGEGEV	TP53I3	16	Q53FA7
GEATKGYLDDPTVPR	G6PD	316	P11413
VDKYDPGALVIPFSG	OLA1	251	Q9NTK5
QGEEIIAYKPPGFSL	NUP205	791	Q92621
PGKEEISYIFEGDPI	PCDH18	361	Q9HCL0
GYGFRVITEKCPEGI	KCNJ5	151	P48544
FPVLVIYKDSERPSG	IGLV3-16	61	A0A075B6K0
GGPAPDVVSDKIYQI	PGM5	141	Q15124
EAFPKGYDIEGPEKV	CFAP95	56	Q5VTT2
VTVAFVVDRRGPGPY	NUP210	1781	Q8TEM1
KGSFLVYPDGDVSRP	CACNA1F	1041	O60840
AIKDILRPTVPYGEF	MAPK7	116	Q13164
LAGFPRKPYEGRVEI	LOXL3	46	P58215
VDYVPSSRKVEFGPG	FRAS1	2846	Q86XX4
SRKAGFFLPPDEYVV	MDC1	1956	Q14676
RGYGKVQAEFPLGPV	NCR1	166	O76036
GKVPVVVSYRPARGV	MFHAS1	921	Q9Y4C4
PVFVVSYAKDLGVPD	SLC16A3	246	O15427
VTEGSGRYIPRKPFP	DPYSL2	461	Q16555
GDVLQPAKPEYRVGE	ASAH2	656	Q9NR71
AVIIPPEVTGYKAGV	ELAPOR1	741	Q6UXG2
PNGKADPYVVVSAGR	FER1L4	1266	A9Z1Z3
GVPYPEAKIGRFVVQ	HSPH1	451	Q92598
SSGYEQGKVPEVPRA	BSN	3186	Q9UPA5
DDFVEYARPVVTGGK	DCUN1D2	241	Q6PH85
GKEPQPGETVIYVAG	PCYT2	206	Q99447
FGGRRPKGVPLVYEA	PCK2	451	Q16822
YPRLIEEDFPGIGDK	MMP13	416	P45452
YTFQLKAVDGGVPPR	PCDH1	681	Q08174
KAVDGGVPPRSAYVG	PCDH1	686	Q08174
AKKEGPYDVVVLPGG	PARK7	61	Q99497
APTPFDRNYGTKLGV	PFKL	666	P17858
SGPRTPDGREIVFYK	PDE6B	301	P35913
GPKTPDGREVNFYKI	PDE6C	306	P51160
EPIVKFPGAVDGATY	PEBP4	76	Q96S96
GSHPERVKVYGPGVE	FLNC	761	Q14315
YIVTPGRDKEPVFAV	MEX3D	306	Q86XN8
SEAPGKCVPYAVIEG	MUL1	56	Q969V5
TFRVTAINKYGPGEP	L1CAM	686	P32004
DAGEVTEAGKAYVPP	GCN1	626	Q92616
PGSRKAVDGVVAVFY	OR10G8	261	Q8NGN5
PVKELLGPDFGYVTR	PADI2	381	Q9Y2J8
YVPGVAFGDIDKLRP	PHF14	411	O94880
TDRIGYFPPGIVEVV	CASKIN2	331	Q8WXE0
YFPPGIVEVVSKRVG	CASKIN2	336	Q8WXE0
EGPVFRPGSKTYVVT	DSG1	381	Q02413
EGPGTYIPRKEVEVV	MVP	146	Q14764
GQYIRLVEPGSPAEK	SLC9A3R1	36	O14745
YGFVVEKTAAARLPP	MVB12A	256	Q96EY5
KNVPPFGLDGVYISE	RELN	1396	P78509
KRTPRSVGYKPDFVG	HPRT1	166	P00492
VFPEPEGRYFLLVVG	INTU	581	Q9ULD6
EDAAPGGSEKLYRVP	ARHGAP6	686	O43182
PGYVLKDGARPDVTE	ALPG	416	P10696
EEYVKPPEGGSVFSI	P2RX2	96	Q9UBL9
GEKRIITIPPFLAYG	FKBP9	216	O95302
NPDDYGGIKVIRVPS	CHRNA5	111	P30532
GAKLPSEYGVIPFES	CSGALNACT2	136	Q8N6G5
EPVAAGSGIPEVKCY	CLCN6	151	P51797
GEKRKVVIPPSFAYG	FKBP7	106	Q9Y680
VYFKRDGEPIDAVPL	IGSF21	181	Q96ID5
SGFEGYVELPPIEGR	CSF2RB	761	P32927
VQKGPLFRAEGYPVS	CD101	26	Q93033
VERYSRKVFVGGLPP	CPEB3	436	Q8NE35
QLVIEAYKSGFEPPG	FNBP1	266	Q96RU3
PPIGDDEVTVGKFYA	CACNA1S	1511	Q13698
PGFYFVEVPEDVAIG	CDH20	391	Q9HBT6
LTPVIGGYPVEKFVA	CRTAP	281	O75718
PVEEAYKRGLVGIEF	DSP	2311	P15924
GKGVAYDVPNPVFLE	CYP51A1	146	Q16850
FVIEEYTGPDPVLVG	CDH11	61	P55287
IKPISIAGGFYGEEP	FOSL2	246	P15408
APEVILRQGYGKPVD	MAST4	751	O15021
GPAIPVVYDFGDAKK	ITLN2	216	Q8WWU7
LAPPYVKGVDESGDV	CEP192	2311	Q8TEP8
GVLYEGKERPKPGFQ	DENND4B	106	O75064
RIGFGAFVDKPVSPY	ITGB3	176	P05106
VIGGKPYVFDRVFPP	KIF5A	41	Q12840
TEEKAKVGPGDRPLY	KHDC4	146	Q7Z7F0
VTGGPLEGPYRLKQF	CA7	81	P43166
ERHEVAKFIGSPPGY	CLPB	416	Q9H078
RPEYTDPKVVAQGEG	B9D1	141	Q9UPM9
PGYAGRTELPESVKA	DNAH10	1936	Q8IVF4
GEIKSYGRPPAQVEI	DNAH2	3111	Q9P225
IYAGVIKSAFDPPDI	SLC12A7	291	Q9Y666
SGDPGKGPITRYVIE	SDK2	1846	Q58EX2
RAPPTYVKVEVPGTF	SALL4	831	Q9UJQ4
YVKVEVPGTFVGPST	SALL4	836	Q9UJQ4
YQVPKEDVDRKPVGG	CFAP74	466	Q9C0B2
FYGPEPALEVARKTL	NLRP6	71	P59044
QDAGVPGYLPREKFL	NOA1	151	Q8NC60
PGKPGVYTRVAVFKD	PRSS56	316	P0CW18
IDIFTPGKPGEYDLE	UPF2	441	Q9HAU5
PDTPEEKIREYFGGF	HNRNPD	191	Q14103
EDGPLPKYGRLVDAV	FREM3	216	P0C091
YKVFPNSAPLEGGTR	MET	566	P08581
GGALEYVPKAVSQPR	REXO1	196	Q8N1G1
YGPKIVPRELAEATG	SLC29A3	436	Q9BZD2
GKVTVRFPPEASGYL	EPRS1	196	P07814
GGPFKAPTIETVVLY	MRPL32	146	Q9BYC8
FEVSPSYVKGGPLRD	SMARCA1	171	P28370
YEAGTKPRDSGVVPV	TMEM126B	6	Q8IUX1
IYKEVIAVQGPPDGT	SYNJ1	881	O43426
EGVRQKAGYITPVPG	MTHFD2	296	P13995
RVYVVIPLLPGFEGD	PLD1	816	Q13393
IEGPPSFRGQSVKYV	RGP1	121	Q92546
IVGKPVGETPDYINF	RGS22	331	Q8NE09
TGAKVERADGYEPPV	RPS3A	246	P61247
IRAGVPKINFSGPDY	PNLDC1	401	Q8NA58
KYAPRPIFISGTIVD	MTR	216	Q99707
GFIRSSEGPKPEKVY	PRRC2C	971	Q9Y520
GPDGPLYKVSVTARD	RAP1GAP	326	P47736
RADKDGPDGSAVPIY	SHISA2	101	Q6UWI4
GVFEGIPTYRFVAPK	SCARB1	291	Q8WTV0
YIPKGTRFGPLIGEI	PRDM1	106	O75626
KVAESGPGLAFIAYP	SLC6A8	376	P48029
NIKGADVGVYIPDPT	MED13	1101	Q9UHV7
KFGDPLGYEDVIPEA	ITGAM	261	P11215
GPLDEPGLGVYKRFV	RHBDL1	156	O75783
ERTGKPFNPLLGETY	OSBPL2	146	Q9H1P3
IYAGGIKSIFDPPVF	SLC12A4	291	Q9UP95
PDTRYLVDGTKPNAG	AATF	301	Q9NY61
EGKPVGTPDAGAYFR	ACSS3	366	Q9H6R3
GKPYSGPVEARVTFV	CILP2	596	Q8IUL8
ESFRVPYDPGLKAGA	PIK3CG	781	P48736
RVFFVYVGGESPLKE	TMX3	151	Q96JJ7
RIKAEYEGDGIPTVF	PAICS	311	P22234
TGERPRYLGIPGDKE	TXNRD1	311	Q16881
ITVKPDFTGLKGPYR	MKS1	236	Q9NXB0
TREKGTEPPFSGIYL	MSRB2	66	Q9Y3D2
EVSRPTERGDKGYVP	STAT4	681	Q14765
TERGDKGYVPSVFIP	STAT4	686	Q14765
KPYVDGKGRELPTAF	SPTAN1	2446	Q13813
GGKYVPRAVLVDLEP	TUBB4B	56	P68371
DVAKDGPGLIFIIYP	SLC6A3	381	Q01959
VGKPYRGVKPVFSIG	TBC1D23	541	Q9NUY8
ARVATYLPAPEGLKF	TNC	706	P24821
TYVEVELFGLPGDPK	PLCB2	701	Q00722
GPGLKADVVLPARYF	POGLUT2	36	Q6UW63
GSEDPLKRPVVYVKG	ZNRF3	171	Q9ULT6
LGASPYPGVKIDEEF	KDR	1101	P35968
KDEDFSPDGGYIPRI	TXNDC12	101	O95881
APTGYIIRGVFTKPI	ZNF185	81	O15231
VLGDGVPPKVAEVIY	USP32	51	Q8NFA0
VPPKVAEVIYCSFGG	USP32	56	Q8NFA0
LRTIGVGKYEFTDPG	KLHL29	296	Q96CT2
VFPDTKPYGALGLEV	KMT2D	4751	O14686
VVGEFKGSFRIYPLP	MYOF	1516	Q9NZM1
GYTLGPKDVPFVHVR	NEB	4996	P20929