Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	CUL3 RASGRP4 ERBB2 ABR PSD3 ARHGAP30 ARHGEF25 CHN2 ARHGEF40 TIMP2	4.19e-06	333	98	10	GO:0051056
GeneOntologyBiologicalProcess	regulation protein catabolic process at postsynapse	CUL3 VHL VHLL	1.22e-05	10	98	3	GO:0140252
GeneOntologyBiologicalProcess	regulation protein catabolic process at synapse	CUL3 VHL VHLL	3.64e-05	14	98	3	GO:0140250
GeneOntologyBiologicalProcess	small GTPase-mediated signal transduction	CUL3 RASGRP4 ERBB2 ABR SH2D3C PSD3 ARHGAP30 ARHGEF25 CHN2 ARHGEF40 TIMP2	4.96e-05	538	98	11	GO:0007264
GeneOntologyBiologicalProcess	negative regulation of hypoxia-inducible factor-1alpha signaling pathway	VHL VHLL	6.68e-05	3	98	2	GO:1902072
GeneOntologyBiologicalProcess	regulation of TORC1 signaling	CUL3 VHL OTUD5 CLEC16A ALG13	1.26e-04	102	98	5	GO:1903432
GeneOntologyBiologicalProcess	response to caffeine	PRSS3 RYR1 HDAC2	1.30e-04	21	98	3	GO:0031000
GeneOntologyBiologicalProcess	regulation of hypoxia-inducible factor-1alpha signaling pathway	VHL VHLL	1.33e-04	4	98	2	GO:1902071
GeneOntologyBiologicalProcess	homeostasis of number of retina cells	VHL VHLL	1.33e-04	4	98	2	GO:0048877
GeneOntologyBiologicalProcess	TORC1 signaling	CUL3 VHL OTUD5 CLEC16A ALG13	1.73e-04	109	98	5	GO:0038202
Domain	-	VHL VHLL	2.73e-05	2	98	2	2.60.40.780
Domain	VHL	VHL VHLL	2.73e-05	2	98	2	PF01847
Domain	VHL	VHL VHLL	2.73e-05	2	98	2	IPR002714
Domain	VHL_tumour_suppress_b/a_dom	VHL VHLL	2.73e-05	2	98	2	IPR022772
Domain	VHL_beta_dom	VHL VHLL	2.73e-05	2	98	2	IPR024053
Domain	IRF-3	IRF5 IRF6	5.63e-04	7	98	2	PF10401
Domain	Interferon_reg_factor-3	IRF5 IRF6	5.63e-04	7	98	2	IPR019471
Domain	IRF-3	IRF5 IRF6	5.63e-04	7	98	2	SM01243
Domain	IRF	IRF5 IRF6	9.58e-04	9	98	2	SM00348
Domain	Interferon_reg_fact_DNA-bd_dom	IRF5 IRF6	9.58e-04	9	98	2	IPR001346
Domain	IRF	IRF5 IRF6	9.58e-04	9	98	2	PF00605
Domain	IRF_1	IRF5 IRF6	9.58e-04	9	98	2	PS00601
Domain	Interferon_reg_fac_CS	IRF5 IRF6	9.58e-04	9	98	2	IPR019817
Domain	IRF_2	IRF5 IRF6	9.58e-04	9	98	2	PS51507
Domain	Rho_GTPase_activation_prot	ABR ARHGAP30 CHN2 PLXNB3	1.19e-03	88	98	4	IPR008936
Domain	OTU	OTUD5 ALG13	2.05e-03	13	98	2	PF02338
Domain	SMAD_FHA_domain	IRF5 IRF6 MDC1	2.57e-03	52	98	3	IPR008984
Domain	OTU	OTUD5 ALG13	2.74e-03	15	98	2	PS50802
Domain	OTU_dom	OTUD5 ALG13	2.74e-03	15	98	2	IPR003323
Domain	SMAD_dom-like	IRF5 IRF6	3.12e-03	16	98	2	IPR017855
Domain	-	IRF5 IRF6	3.12e-03	16	98	2	2.60.200.10
Domain	RhoGAP	ABR ARHGAP30 CHN2	4.23e-03	62	98	3	SM00324
Domain	RhoGAP	ABR ARHGAP30 CHN2	4.43e-03	63	98	3	PF00620
Domain	DH_1	ABR ARHGEF25 ARHGEF40	4.43e-03	63	98	3	PS00741
Domain	RHOGAP	ABR ARHGAP30 CHN2	4.63e-03	64	98	3	PS50238
Domain	RhoGAP_dom	ABR ARHGAP30 CHN2	4.63e-03	64	98	3	IPR000198
Domain	-	ABR ARHGAP30 CHN2	4.63e-03	64	98	3	1.10.555.10
Domain	DAG/PE-bd	RASGRP4 CHN2	5.36e-03	21	98	2	IPR020454
Domain	SAM_1	PPFIBP1 SAMD5 SCML1	5.49e-03	68	98	3	PF00536
Domain	FCH	FNBP1L FCHO2	5.88e-03	22	98	2	PF00611
Domain	FCH	FNBP1L FCHO2	5.88e-03	22	98	2	SM00055
Domain	RhoGEF	ABR ARHGEF25 ARHGEF40	5.95e-03	70	98	3	PF00621
Domain	DH_2	ABR ARHGEF25 ARHGEF40	5.95e-03	70	98	3	PS50010
Domain	DH-domain	ABR ARHGEF25 ARHGEF40	6.19e-03	71	98	3	IPR000219
Domain	-	ABR ARHGEF25 ARHGEF40	6.19e-03	71	98	3	1.20.900.10
Domain	FCH_dom	FNBP1L FCHO2	6.42e-03	23	98	2	IPR001060
Pathway	REACTOME_RHOBTB3_ATPASE_CYCLE	CUL3 VHL VHLL	2.51e-05	11	77	3	MM15681
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZSWIM8 ERBB2 ZNF609 ERCC6 TTC28 FXR2 POLR2A VPS50 RSF1 SKIL ARHGEF40 BRD8 SCML1 WDR62 HDAC2 ALG13	1.41e-07	1116	101	16	31753913
Pubmed	Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice.	VHL VHLL MMP13	2.37e-07	5	101	3	27122313
Pubmed	The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2.	VHL VHLL KLC1	4.72e-07	6	101	3	17825299
Pubmed	Mice lacking HSP90beta fail to develop a placental labyrinth.	VHL ESX1 VHLL	8.25e-07	7	101	3	10654595
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HSDL2 FXR2 PPFIBP1 TRMT112 POLR2A PSMB1 PSMC2 APEX1 FNBP1L NAMPT MDC1 EIF4G1 ATP1A1 HECTD1 G6PD HDAC2	3.18e-06	1415	101	16	28515276
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	PRSS3 MLEC POLR2A PSMB1 APEX1 RYR1 NSDHL NAMPT EIF4G1 ATP1A1 G6PD ALG13	4.05e-06	807	101	12	30575818
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ERBB2 ABR MLEC TTC28 ERCC6L PPFIBP1 PSD3 PSMC2 FCHO2 EIF4G1 ATP1A1	6.96e-06	708	101	11	39231216
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CUL3 MED30 TRMT112 POLR2A PSMB1 RSF1 APEX1 BRD8 NAMPT MDC1 EIF4G1 G6PD HDAC2	7.78e-06	1014	101	13	32416067
Pubmed	The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism.	VHL VHLL	8.35e-06	2	101	2	27422990
Pubmed	Neuroprotective effects respond to cerebral ischemia without susceptibility to HB-tumorigenesis in VHL heterozygous knockout mice.	VHL VHLL	8.35e-06	2	101	2	28574654
Pubmed	Endothelial function of von Hippel-Lindau tumor suppressor gene: control of fibroblast growth factor receptor signaling.	VHL VHLL	8.35e-06	2	101	2	18559510
Pubmed	Acute inactivation of the VHL gene contributes to protective effects of ischemic preconditioning in the mouse kidney.	VHL VHLL	8.35e-06	2	101	2	18957870
Pubmed	pVHL and GSK3beta are components of a primary cilium-maintenance signalling network.	VHL VHLL	8.35e-06	2	101	2	17450132
Pubmed	Osteocytic HIF-1α Pathway Manipulates Bone Micro-structure and Remodeling via Regulating Osteocyte Terminal Differentiation.	VHL VHLL	8.35e-06	2	101	2	35118061
Pubmed	Cloning of the rat homologue of the von Hippel-Lindau tumor suppressor gene and its non-somatic mutation in rat renal cell carcinomas.	VHL VHLL	8.35e-06	2	101	2	7493907
Pubmed	Expression of interstitial collagenase is restricted to skeletal tissue during mouse embryogenesis.	TIMP2 MMP13	8.35e-06	2	101	2	7768998
Pubmed	CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma.	VHL VHLL	8.35e-06	2	101	2	27358011
Pubmed	Cancer. Many vessels, faulty gene.	VHL VHLL	8.35e-06	2	101	2	10353237
Pubmed	The VHL tumor suppressor in development and disease: functional studies in mice by conditional gene targeting.	VHL VHLL	8.35e-06	2	101	2	15908240
Pubmed	Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis.	VHL VHLL	8.35e-06	2	101	2	21925138
Pubmed	VHL Inactivation in Precancerous Kidney Cells Induces an Inflammatory Response via ER Stress-Activated IRE1α Signaling.	VHL VHLL	8.35e-06	2	101	2	28533271
Pubmed	Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma.	VHL VHLL	8.35e-06	2	101	2	8603073
Pubmed	Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular disease.	VHL VHLL	8.35e-06	2	101	2	17609290
Pubmed	Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis.	VHL VHLL	8.35e-06	2	101	2	24999110
Pubmed	Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice.	VHL VHLL	8.35e-06	2	101	2	21242957
Pubmed	Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.	VHL VHLL	8.35e-06	2	101	2	15899860
Pubmed	Genetic and functional analysis of the von Hippel-Lindau (VHL) tumour suppressor gene promoter.	VHL VHLL	8.35e-06	2	101	2	12114475
Pubmed	Expression of the Von Hippel-Lindau tumor suppressor gene, VHL, in human fetal kidney and during mouse embryogenesis.	VHL VHLL	8.35e-06	2	101	2	8521303
Pubmed	Aberrant Expression of TIMP-2 and PBEF Genes in the Placentae of Cloned Mice Due to Epigenetic Reprogramming Error.	NAMPT TIMP2	8.35e-06	2	101	2	27855185
Pubmed	Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney.	VHL VHLL	8.35e-06	2	101	2	38502859
Pubmed	Drosophila von Hippel-Lindau tumor suppressor gene function in epithelial tubule morphogenesis.	VHL VHLL	8.35e-06	2	101	2	20516215
Pubmed	Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates.	ERCC6 APEX1	8.35e-06	2	101	2	17567611
Pubmed	Deletion of Vhl in Dmp1-Expressing Cells Causes Microenvironmental Impairment of B Cell Lymphopoiesis.	VHL VHLL	8.35e-06	2	101	2	35250971
Pubmed	Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis.	VHL VHLL	8.35e-06	2	101	2	26488390
Pubmed	Comparative sequence analysis of the VHL tumor suppressor gene.	VHL VHLL	8.35e-06	2	101	2	10857749
Pubmed	Cloning and characterization of a mouse gene with homology to the human von Hippel-Lindau disease tumor suppressor gene: implications for the potential organization of the human von Hippel-Lindau disease gene.	VHL VHLL	8.35e-06	2	101	2	7850784
Pubmed	Tumor suppressor VHL functions in the control of mitotic fidelity.	VHL VHLL	8.35e-06	2	101	2	24362914
Pubmed	A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome.	VHL VHLL	8.35e-06	2	101	2	22977222
Pubmed	Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.	VHL VHLL	8.35e-06	2	101	2	21652636
Pubmed	Matrix metalloprotease activity is an essential link between mechanical stimulus and mesenchymal stem cell behavior.	TIMP2 MMP13	8.35e-06	2	101	2	17495113
Pubmed	Vascular defects and liver damage by the acute inactivation of the VHL gene during mouse embryogenesis.	VHL VHLL	8.35e-06	2	101	2	16652107
Pubmed	E3 Ubiquitin Ligase Von Hippel-Lindau Protein Promotes Th17 Differentiation.	VHL VHLL	8.35e-06	2	101	2	32690659
Pubmed	Genetic deletion of the long isoform of the von Hippel-Lindau tumour suppressor gene product alters microtubule dynamics.	VHL VHLL	8.35e-06	2	101	2	23541568
Pubmed	A role for von Hippel-Lindau protein in pancreatic beta-cell function.	VHL VHLL	8.35e-06	2	101	2	19033400
Pubmed	Inactivation of Vhl in osteochondral progenitor cells causes high bone mass phenotype and protects against age-related bone loss in adult mice.	VHL VHLL	8.35e-06	2	101	2	23999831
Pubmed	ErbB2-driven downregulation of the transcription factor Irf6 in breast epithelial cells is required for their 3D growth.	ERBB2 IRF6	8.35e-06	2	101	2	30545388
Pubmed	Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations.	VHL VHLL	8.35e-06	2	101	2	19340311
Pubmed	Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.	VHL VHLL	8.35e-06	2	101	2	11171994
Pubmed	VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis.	VHL VHLL	8.35e-06	2	101	2	38618956
Pubmed	Podocytes contribute to the formation of glomerular crescents.	VHL VHLL	8.35e-06	2	101	2	18199804
Pubmed	Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice.	VHL VHLL	8.35e-06	2	101	2	14604887
Pubmed	The VHL tumor suppressor and HIF: insights from genetic studies in mice.	VHL VHLL	8.35e-06	2	101	2	18219317
Pubmed	Epigenetic characterization of the PBEF and TIMP-2 genes in the developing placentae of normal mice.	NAMPT TIMP2	8.35e-06	2	101	2	21871178
Pubmed	Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease.	VHL VHLL	8.35e-06	2	101	2	37833251
Pubmed	Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes.	ERCC6 POLR2A	8.35e-06	2	101	2	9372911
Pubmed	Von Hippel-Lindau mutations disrupt vascular patterning and maturation via Notch.	VHL VHLL	8.35e-06	2	101	2	29467323
Pubmed	Targeted deletion of von-Hippel-Lindau in the proximal tubule conditions the kidney against early diabetic kidney disease.	VHL VHLL	8.35e-06	2	101	2	37626062
Pubmed	Necrotizing crescentic glomerulonephritis--a conditional knockout model discloses new therapeutic challenges.	VHL VHLL	8.35e-06	2	101	2	17210602
Pubmed	Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism.	VHL VHLL	8.35e-06	2	101	2	29431735
Pubmed	Tubular von Hippel-Lindau knockout protects against rhabdomyolysis-induced AKI.	VHL VHLL	8.35e-06	2	101	2	23970125
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ZNF609 TTC28 ERCC6L FXR2 POLR2A VPS50 NSDHL MDC1 ARNT2 HECTD1 WDR62	9.63e-06	733	101	11	34672954
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	CUL3 PSMB1 PSMC2 BRD8 EIF4G1 ATP1A1 CLEC16A KLC1 HDAC2	1.46e-05	495	101	9	28581483
Pubmed	Armc5 deletion causes developmental defects and compromises T-cell immune responses.	CUL3 ERCC6L POLR2A	1.57e-05	17	101	3	28169274
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZSWIM8 ERBB2 ABR BTBD10 RSF1 APEX1 BRD8 EIF4G1 CLEC16A JAM3 KLC1 ALG13	1.59e-05	925	101	12	28986522
Pubmed	WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.	ERBB2 ABR TTC28 HECTD1	1.63e-05	52	101	4	30655611
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZSWIM8 FXR2 POLR2A RSF1 PSMC2 MDC1 EIF4G1 ATP1A1 HECTD1 HDAC2	2.11e-05	653	101	10	22586326
Pubmed	Inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) in granulocytes contributes to development of liver hemangiomas in a mouse model.	VHL VHLL	2.50e-05	3	101	2	27733136
Pubmed	Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice.	VHL VHLL	2.50e-05	3	101	2	9256442
Pubmed	The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia.	VHL VHLL	2.50e-05	3	101	2	27068470
Pubmed	Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis.	VHL VHLL	2.50e-05	3	101	2	18667485
Pubmed	Activation of HIFa pathway in mature osteoblasts disrupts the integrity of the osteocyte/canalicular network.	VHL VHLL	2.50e-05	3	101	2	25806791
Pubmed	Biomarker triplet NAMPT/VEGF/HER2 as a de novo detection panel for the diagnosis and prognosis of human breast cancer.	ERBB2 NAMPT	2.50e-05	3	101	2	26531769
Pubmed	Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth.	VHL VHLL	2.50e-05	3	101	2	14691554
Pubmed	Phospholamban Is Downregulated by pVHL-Mediated Degradation through Oxidative Stress in Failing Heart.	VHL VHLL	2.50e-05	3	101	2	29068413
Pubmed	Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.	VHL VHLL	2.50e-05	3	101	2	20804974
Pubmed	Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription.	VHL VHLL	2.50e-05	3	101	2	11859074
Pubmed	Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice.	VHL VHLL	2.50e-05	3	101	2	23606570
Pubmed	VHL loss causes spindle misorientation and chromosome instability.	VHL VHLL	2.50e-05	3	101	2	19620968
Pubmed	HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore.	VHL VHLL	2.50e-05	3	101	2	25063991
Pubmed	Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis.	VHL VHLL	2.50e-05	3	101	2	16407833
Pubmed	Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency.	VHL VHLL	2.50e-05	3	101	2	19147412
Pubmed	Tumor suppression by the von Hippel-Lindau protein requires phosphorylation of the acidic domain.	VHL VHLL	2.50e-05	3	101	2	15824109
Pubmed	Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.	VHL VHLL	2.50e-05	3	101	2	18096761
Pubmed	Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases.	VHL VHLL	2.50e-05	3	101	2	33512384
Pubmed	Expression of the von Hippel-Lindau-binding protein-1 (Vbp1) in fetal and adult mouse tissues.	VHL VHLL	2.50e-05	3	101	2	9931330
Pubmed	Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor.	VHL VHLL	2.50e-05	3	101	2	19419968
Pubmed	The von Hippel-Lindau Tumor Suppressor Gene Mutations Modulate Lipocalin-2 Expression in Ferroptotic-Inflammatory Pathways.	VHL VHLL	2.50e-05	3	101	2	36718277
Pubmed	Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.	VHL VHLL	2.50e-05	3	101	2	14500363
Pubmed	Role of compartmentalization on HiF-1α degradation dynamics during changing oxygen conditions: a computational approach.	VHL VHLL	2.50e-05	3	101	2	25338163
Pubmed	Hypoxia inducible factor 1 alpha regulates T cell receptor signal transduction.	VHL VHLL	2.50e-05	3	101	2	16286658
Pubmed	The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma.	VHL VHLL	2.50e-05	3	101	2	28329682
Pubmed	Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.	VHL VHLL	2.50e-05	3	101	2	15128677
Pubmed	The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.	VHL VHLL	2.50e-05	3	101	2	17549257
Pubmed	Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency.	VHL VHLL	2.50e-05	3	101	2	16061637
Pubmed	Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons.	POLR2A PIEZO2	2.50e-05	3	101	2	38743566
Pubmed	The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control.	VHL VHLL	2.50e-05	3	101	2	31123085
Pubmed	Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF-1α.	VHL VHLL	2.50e-05	3	101	2	36987917
Pubmed	Pancreatic cyst development: insights from von Hippel-Lindau disease.	VHL VHLL	2.50e-05	3	101	2	23384121
Pubmed	Clinical implications of HER-2/neu overexpression and proteolytic activity imbalance in breast cancer.	ERBB2 TIMP2	2.50e-05	3	101	2	17613170
Pubmed	TXNIP interaction with the Her-1/2 pathway contributes to overall survival in breast cancer.	ERBB2 TXNIP	2.50e-05	3	101	2	25605021
Interaction	SDF4 interactions	CUL3 TTC28 VPS50 SH2D3C SMG8 BRD8 TIMP2 CLEC16A	7.34e-07	151	98	8	int:SDF4
Interaction	BTBD10 interactions	CUL3 BTBD10 APEX1 HECTD1	3.60e-06	22	98	4	int:BTBD10
Interaction	ZC3H7B interactions	OARD1 CUL3 FXR2 EIF4G1 HECTD1	5.32e-06	52	98	5	int:ZC3H7B
Interaction	HERC2 interactions	MED30 ABR MLEC HSDL2 PSMC2 TXNIP MDC1 EIF4G1 HECTD1 CLEC16A WDR62 HDAC2	5.95e-06	503	98	12	int:HERC2
Interaction	RASGRP1 interactions	VHL APEX1 TIMP2	1.79e-05	11	98	3	int:RASGRP1
Interaction	NEURL4 interactions	HSDL2 POLR2A PSMC2 APEX1 TXNIP HECTD1	2.18e-05	116	98	6	int:NEURL4
Interaction	CAMK2G interactions	CUL3 ERBB2 FXR2 PSMB1 APEX1 RYR1 CALML4 CLEC16A	2.25e-05	240	98	8	int:CAMK2G
Interaction	POLR2C interactions	CUL3 MED30 ERCC6 OTUD5 POLR2A PSMC2 MDC1 CLEC16A KLC1	4.01e-05	338	98	9	int:POLR2C
Interaction	PSMC3 interactions	CUL3 VHL ERBB2 PSMB1 PSMC2 SCML1 EIF4G1 ATP1A1 KLC1 CCDC40	4.20e-05	425	98	10	int:PSMC3
Interaction	PSMC4 interactions	CUL3 PSMB1 PSMC2 APEX1 CMYA5 TIMP2 EIF4G1 ATP1A1 KLC1	4.59e-05	344	98	9	int:PSMC4
Interaction	MED18 interactions	MED30 POLR2A AFMID G6PD HDAC2	4.69e-05	81	98	5	int:MED18
Interaction	UHRF1 interactions	CUL3 SH2D3C RSF1 APEX1 GLDC HECTD1 HDAC2	7.05e-05	208	98	7	int:UHRF1
Interaction	TXNIP interactions	VHL ZSWIM8 POLR2A PSMC2 TXNIP ATP1A1 HDAC2	7.95e-05	212	98	7	int:TXNIP
Interaction	POLR2B interactions	CUL3 MED30 ERCC6 OTUD5 POLR2A GLDC MDC1 HECTD1 CLEC16A	8.20e-05	371	98	9	int:POLR2B
Interaction	PRRC2C interactions	FXR2 PPFIBP1 HECTD1 CLEC16A G6PD KLC1 HDAC2 ALG13	8.57e-05	290	98	8	int:PRRC2C
Interaction	STC2 interactions	CARHSP1 AFMID ARHGEF40 TIMP2	8.68e-05	48	98	4	int:STC2
Interaction	RADX interactions	APEX1 MDC1 HECTD1 CLEC16A	9.42e-05	49	98	4	int:RADX
Interaction	NAPRT interactions	TRMT112 APEX1 NAMPT NENF	1.02e-04	50	98	4	int:NAPRT
Interaction	RIF1 interactions	CUL3 ERCC6 SH2D3C APEX1 MDC1 HECTD1 CLEC16A	1.15e-04	225	98	7	int:RIF1
Interaction	PSMD3 interactions	CUL3 ERBB2 ERCC6 PSMB1 PSMC2 EIF4G1 ATP1A1 HECTD1 KLC1	1.20e-04	390	98	9	int:PSMD3
Interaction	PSMC5 interactions	CUL3 ERCC6 PSMB1 PSMC2 APEX1 BRD8 TIMP2 EIF4G1 ATP1A1 KLC1	1.23e-04	484	98	10	int:PSMC5
Interaction	PSMC2 interactions	CUL3 PSMB1 PSMC2 SKIL TXNIP TIMP2 EIF4G1 ATP1A1 KLC1	1.27e-04	393	98	9	int:PSMC2
Interaction	SPOCD1 interactions	VHL APEX1	1.40e-04	4	98	2	int:SPOCD1
Interaction	ATXN2 interactions	CUL3 VHL FXR2 CHGB GLDC MDC1 EIF4G1 ALG13	1.42e-04	312	98	8	int:ATXN2
Interaction	PABPC1 interactions	CUL3 ERBB2 CTTNBP2 PSMC2 APEX1 TIMP2 GLDC EIF4G1 ATP1A1 KLC1 HDAC2 ALG13	1.46e-04	699	98	12	int:PABPC1
Interaction	CIITA interactions	CUL3 POLR2A PSMC2 HDAC2	1.48e-04	55	98	4	int:CIITA
Interaction	EXOC2 interactions	CUL3 ESX1 HECTD1 CLEC16A HDAC2	1.69e-04	106	98	5	int:EXOC2
Interaction	NELFCD interactions	PRSS3 PSMB1 APEX1 EIF4G1 ATP1A1	1.69e-04	106	98	5	int:NELFCD
Interaction	LARP4B interactions	CUL3 FXR2 GLDC HECTD1 CLEC16A HDAC2 ALG13	1.72e-04	240	98	7	int:LARP4B
Interaction	ZC3H14 interactions	CUL3 APEX1 AK7 GLDC HECTD1 HDAC2	1.77e-04	169	98	6	int:ZC3H14
Interaction	ELOA interactions	CUL3 VHL ERCC6 POLR2A APEX1 HECTD1 HDAC2	1.81e-04	242	98	7	int:ELOA
Interaction	OGG1 interactions	ERCC6 CHGB HDAC2	1.84e-04	23	98	3	int:OGG1
Interaction	PLK1 interactions	CUL3 ZSWIM8 ERCC6L PSMB1 RSF1 APEX1 SCML1 PITPNA HECTD1 HDAC2	1.88e-04	510	98	10	int:PLK1
Interaction	GTPBP2 interactions	CUL3 VHL PSMB1 IRF5	1.95e-04	59	98	4	int:GTPBP2
Interaction	CPSF2 interactions	CUL3 POLR2A GLDC MDC1 HECTD1 HDAC2	2.01e-04	173	98	6	int:CPSF2
Interaction	HRAS interactions	CUL3 RASGRP4 ERBB2 ABR TTC28 PPFIBP1 FCHO2 C1orf21 SCML1 ATP1A1 HECTD1 JAM3	2.05e-04	725	98	12	int:HRAS
Interaction	PAPSS2 interactions	VHL APEX1 HECTD1 HDAC2	2.08e-04	60	98	4	int:PAPSS2
Interaction	HSPA4L interactions	CUL3 ERBB2 ZNF609 TXNIP GLDC HECTD1 CLEC16A	2.20e-04	250	98	7	int:HSPA4L
Interaction	PSMD9 interactions	CUL3 PSMB1 VPS50 PSMC2 CLEC16A CCDC40	2.21e-04	176	98	6	int:PSMD9
Interaction	CCAR2 interactions	CUL3 FXR2 OTUD5 SH2D3C PSMC2 GLDC EIF4G1 HECTD1	2.40e-04	337	98	8	int:CCAR2
Coexpression	DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN	ERBB2 ABR MLEC POLR2A ITGA7 TXNIP GLDC VCAN PITPNA CLEC16A	1.18e-07	276	101	10	M3063
Coexpression	BENPORATH_SOX2_TARGETS	OARD1 ERBB2 COL12A1 PSMB1 RSF1 PSMC2 APEX1 LHPP PPP1R15A SKIL C1orf21 VCAN MDC1 HDAC2	8.72e-07	734	101	14	M3835
Coexpression	GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN	ABR LILRB2 TIMP2 VCAN EIF4G1 ATP1A1 G6PD	1.27e-05	200	101	7	M4486
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 SAMD5 PSD3 TMEM132C PIEZO2 VCAN PCDH15	2.64e-07	190	101	7	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CTTNBP2 TTC28 SAMD5 TMEM132C PIEZO2 VCAN PCDH15	3.04e-07	194	101	7	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TTC28 PPFIBP1 PSD3 TMEM132C PIEZO2 VCAN ARNT2	3.04e-07	194	101	7	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABR LAT2 LILRB2 ARHGAP30 ZNF710 NAMPT VCAN	3.37e-07	197	101	7	1eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCell	facs-MAT-Fat-18m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LAT2 IRF5 ARHGAP30 CHN2 RYR1	2.26e-06	167	101	6	c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCell	facs-Lung-EPCAM-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LAT2 IRF5 ARHGAP30 RYR1 C1orf21	3.17e-06	177	101	6	7bc92314b22a876296a4e2db51e7fb0fdfd69379
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	CTTNBP2 SAMD5 ARHGAP30 RYR1 GLDC CALML4	3.38e-06	179	101	6	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	RV\|World / Chamber and Cluster_Paper	HSDL2 PPFIBP1 CMYA5 CHN2 TMEM132C TXNIP	3.60e-06	181	101	6	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PRSS3 HSDL2 PCDHGA4 CHN2 ABCB4 C1orf21	3.96e-06	184	101	6	667846c422cfa27e949a24844a305df859cb6760
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRSS3 HSDL2 PCDHGA4 CHN2 ABCB4 C1orf21	3.96e-06	184	101	6	a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	LILRB2 LHPP IRF5 FCHO2 ITGA7 VCAN	4.21e-06	186	101	6	a16ecf70271894a842925f232009e2623d16947e
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CTTNBP2 SAMD5 CMYA5 TMEM132C PIEZO2 PCDH15	4.62e-06	189	101	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAT2 LILRB2 ARHGAP30 ZNF710 NAMPT VCAN	4.91e-06	191	101	6	47a2afc4102199b4bc76bd01b2967c8016186462
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CTTNBP2 PPFIBP1 CMYA5 PIEZO2 TIMP2 ACKR2	5.06e-06	192	101	6	d43caf42ec744e895137f31ef65a990e250669d2
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 SAMD5 PSD3 TMEM132C PIEZO2 PCDH15	5.21e-06	193	101	6	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	CTTNBP2 TTC28 SAMD5 TMEM132C PIEZO2 PCDH15	5.21e-06	193	101	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	control-Lymphocytic-CD4_T_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RASGRP4 LILRB2 PPP1R15A ARHGEF40 NAMPT TIMP2	5.36e-06	194	101	6	c2ae2ea848d78725455dcb6be9f1d8933745fa80
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TTC28 PPFIBP1 PSD3 TMEM132C PIEZO2 VCAN	5.52e-06	195	101	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABR LILRB2 ARHGAP30 ZNF710 NAMPT VCAN	5.52e-06	195	101	6	10ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABR LAT2 RYR1 ZNF710 NAMPT VCAN	5.86e-06	197	101	6	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	10x5'-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes\|lymph-node_spleen / Manually curated celltypes from each tissue	RASGRP4 LILRB2 NAMPT TIMP2 VCAN CALML4	5.86e-06	197	101	6	67f19dd30adb03300f04219d0295bc1c1788f626
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LILRB2 PPP1R15A ARHGEF40 NAMPT TIMP2 VCAN	6.03e-06	198	101	6	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTN4 COL12A1 ITGA7 TMEM132C TIMP2 JAM3	6.21e-06	199	101	6	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CARHSP1 PPFIBP1 SH2D3C FNBP1L AFMID JAM3	6.21e-06	199	101	6	14a7c4cf4bb3d43fd32ec9cc74f6625b225ffaa1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial\|6m / Sample Type, Dataset, Time_group, and Cell type.	COL12A1 PPFIBP1 PPP1R15A TXNIP PIEZO2 VCAN	6.39e-06	200	101	6	2cc98abf11f5b58707de45a2282f03d47f00f035
ToppCell	mild-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LILRB2 PPP1R15A ARHGEF40 NAMPT TIMP2 VCAN	6.39e-06	200	101	6	934c2efc780318c66d667ca75be0de350361d351
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial-Proteoglycan-expressing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	COL12A1 PPFIBP1 PPP1R15A TXNIP PIEZO2 VCAN	6.39e-06	200	101	6	0f7431f670f3a175377cefae3479403a881bb8fb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	CTTNBP2 FNBP1L VCAN KLC1 HDAC2	2.21e-05	148	101	5	a1269312903fc27830c1835dabf660c659a711be
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CNTN4 CMYA5 TMEM132C VCAN PCDH15	2.76e-05	155	101	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LAT2 IRF5 RYR1 MMP13	3.31e-05	161	101	5	787f91f906756ef570c0d02936c3cdfafb3f7454
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LAT2 IRF5 RYR1 MMP13	3.31e-05	161	101	5	3db97af49520dc8cbafb4454d8afd9d588160e89
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LAT2 IRF5 RYR1 MMP13	3.31e-05	161	101	5	f1d258c81bcf0f3c52bd20aa58faa9a5fd888168
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 IRF5 ARHGAP30 VCAN G6PD	3.62e-05	164	101	5	45a6d809d92fd4eee906da3c812282bacffc9f2f
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 IRF5 ARHGAP30 VCAN G6PD	3.62e-05	164	101	5	aa4358311fc767c292897e3328309d1bcda392d4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LILRB2 IRF5 CHN2 TIMP2 VCAN	3.83e-05	166	101	5	28a44448a0b0d72459e8fe84ce5d666f16f514b3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LILRB2 IRF5 CHN2 TIMP2 VCAN	3.83e-05	166	101	5	2a04915d534a83e65aa168435d6856125b5bdd78
ToppCell	Endothelial-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	PPFIBP1 PIEZO2 ACKR2 JAM3 PDZD4	3.94e-05	167	101	5	6a03d16165e0b003092c39972928981abd4a75aa
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 LAT2 IRF5 CHN2 C1orf21	3.94e-05	167	101	5	9526e2c7673d569d04e0728a2526318e67432e0a
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 IRF5 ARHGAP30 RYR1 ZNF710	4.17e-05	169	101	5	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAT2 IRF5 CHN2 RYR1 C1orf21	4.17e-05	169	101	5	735655e75511c5c41aca667909e8bb52a0ad7fc6
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 IRF5 ARHGAP30 RYR1 ZNF710	4.17e-05	169	101	5	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 IRF5 ARHGAP30 RYR1 ZNF710	4.17e-05	169	101	5	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LAT2 IRF5 RYR1 C1orf21	4.41e-05	171	101	5	a3e3fe0cbab21abb178c482f5951e576529f7e30
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAT2 IRF5 CHN2 RYR1 C1orf21	4.41e-05	171	101	5	38a05b5ec8ef8f09a2399994c6b4b9a707918ec1
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAT2 IRF5 ARHGAP30 RYR1 PITPNA	4.54e-05	172	101	5	6b01448443cf8392ed8248ff452b80c31240b85d
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIBP1 RYR1 C1orf21 CLEC16A WDR62	4.54e-05	172	101	5	7fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	CNTN4 CTTNBP2 TTC28 VCAN ARNT2	4.54e-05	172	101	5	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAT2 IRF5 ARHGAP30 RYR1 PITPNA	4.54e-05	172	101	5	0c0ae2da3cba6022403434567800f16e61a34a2b
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAT2 IRF5 ARHGAP30 RYR1 PITPNA	4.54e-05	172	101	5	d80c207f3489be2da2f40f47a7835cb73c949c3e
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 IRF5 ARHGAP30 RYR1 C1orf21	4.54e-05	172	101	5	e680abead2da75e50774da02384eb2729c839c01
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIBP1 RYR1 C1orf21 CLEC16A WDR62	4.54e-05	172	101	5	2a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAT2 IGHV1-69-2 LILRB2 SH2D3C ARHGAP30	4.66e-05	173	101	5	b367b62309389e8b6a65de83c2434dc8ec905985
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAT2 PPP1R15A ARHGEF25 CHN2 PDZD4	4.79e-05	174	101	5	009e88a6c79689a5d88b0af50aa89aa03b33f800
ToppCell	facs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 LAT2 IRF5 CHN2 RYR1	4.79e-05	174	101	5	c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 LAT2 IRF5 ARHGAP30 RYR1	5.06e-05	176	101	5	7b5e50eb144bf43ca0cf354a466eb58b976a79f1
ToppCell	Monocytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	LILRB2 CHN2 BRD8 NAMPT VCAN	5.06e-05	176	101	5	5b5f8655b0c6c56f98f70bce13e71f017d4b75a5
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 IRF5 ARHGAP30 RYR1 C1orf21	5.20e-05	177	101	5	3cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAT2 IRF5 ARHGAP30 RYR1 C1orf21	5.48e-05	179	101	5	33ed9270d257895ff3b40df2c1af878119c9f492
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 SH2D3C PCDH15 ACKR2 PDZD4	5.48e-05	179	101	5	9fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAT2 IRF5 ARHGAP30 RYR1 C1orf21	5.48e-05	179	101	5	b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RASGRP4 LILRB2 NAMPT GLDC VCAN	5.78e-05	181	101	5	71e55acd1d8e4307e56534c74a50e7be4d1dda0d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CTTNBP2 SAMD5 TMEM132C PIEZO2 PCDH15	5.78e-05	181	101	5	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-5\|TCGA-Breast / Sample_Type by Project: Shred V9	ERBB2 ERCC6L MPHOSPH6 MMP13 G6PD	5.93e-05	182	101	5	9e48d5b634603bc7a8d29290202a311457678328
ToppCell	facs-Lung-EPCAM-24m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LAT2 IRF5 ARHGAP30 RYR1	6.09e-05	183	101	5	f524501dec1dccbf44100a61395116e4525bdc89
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	CTTNBP2 SAMD5 PSD3 TXNIP ARNT2	6.09e-05	183	101	5	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LAT2 IRF5 ARHGAP30 RYR1	6.09e-05	183	101	5	107cc756c45d6e92181659868d91188814dae66d
ToppCell	ILEUM-inflamed-(7)_Lymphatics\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPFIBP1 CMYA5 PIEZO2 TIMP2 ACKR2	6.41e-05	185	101	5	d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 LAT2 IRF5 ARHGAP30 RYR1	6.41e-05	185	101	5	ed7b26bdebfd0df2b4f5020a855a052d94ae7219
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SAMD5 TMEM132C PIEZO2 GLDC PCDH15	6.41e-05	185	101	5	f4ac62009c0ad3346e71b809e17727303c4df153
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	CNTN4 COL12A1 PIEZO2 C1orf21 JAM3	6.57e-05	186	101	5	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	facs-Brain_Myeloid-Hippocampus_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS3 IRF5 ZNF710 TIMP2 EIF4G1	6.57e-05	186	101	5	28699e3574d3a183190bdb6c5db2219167d41579
ToppCell	facs-Brain_Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS3 IRF5 ZNF710 TIMP2 EIF4G1	6.57e-05	186	101	5	f3345fad9559ec222062a6f516b9d3f815d98acf
ToppCell	facs-Brain_Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS3 IRF5 ZNF710 TIMP2 EIF4G1	6.57e-05	186	101	5	77baa0075e53ccb654a561e3289eba41deab8561
ToppCell	facs-Brain_Myeloid-Hippocampus_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS3 IRF5 ZNF710 TIMP2 EIF4G1	6.57e-05	186	101	5	eb1d1941cd6e4d9f0655aff3ba8df3c29c06b3a2
ToppCell	facs-Brain_Myeloid-Hippocampus_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS3 IRF5 ZNF710 TIMP2 EIF4G1	6.57e-05	186	101	5	06e6e805f90d92c870f36b79fa0749988a4595bb
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	CNTN4 COL12A1 TTC28 ITGA7 VCAN	6.74e-05	187	101	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPFIBP1 SAMD5 TMEM132C PIEZO2 VCAN	6.74e-05	187	101	5	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LAT2 LILRB2 IRF5 ARHGAP30 RYR1	6.91e-05	188	101	5	8fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RASGRP4 CTTNBP2 LILRB2 CHN2 VCAN	7.09e-05	189	101	5	2aebea7a6c2f83112d7c504b742f2c04b92e459a
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	HSDL2 PPFIBP1 CMYA5 CHN2 TXNIP	7.09e-05	189	101	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTTNBP2 LAT2 PPP1R15A SKIL CHN2	7.09e-05	189	101	5	f01158bb15df3117fae1271bf8cf8c2501422671
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	PPFIBP1 TMEM132C NAMPT VCAN PCDH15	7.09e-05	189	101	5	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTTNBP2 SAMD5 RYR1 GLDC CALML4	7.27e-05	190	101	5	8a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 TMEM132C PIEZO2 VCAN PCDH15	7.45e-05	191	101	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RASGRP4 LILRB2 ARHGEF40 NAMPT VCAN	7.45e-05	191	101	5	5d6ef70cc15ec5e983a953e547e40f9c06e355fb
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	CNTN4 COL12A1 PIEZO2 C1orf21 JAM3	7.45e-05	191	101	5	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TMEM132C PIEZO2 TIMP2 GLDC PCDH15	7.45e-05	191	101	5	782bc7946417549ffd39e5b596db659436fa01ba
ToppCell	(11)_FOXN4+-(0)_Reference\|(11)_FOXN4+ / shred by cell type by condition	MED30 ITGA7 MDC1 CLEC16A NENF	7.64e-05	192	101	5	ef06f96b934dd05b40025f8215b6d919d3a17045
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 SAMD5 TMEM132C PIEZO2 PCDH15	7.64e-05	192	101	5	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RASGRP4 LAT2 LILRB2 IRF5 RYR1	7.64e-05	192	101	5	b204ef6e05170855259b902829a1700094eb9159
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LILRB2 SKIL NAMPT TIMP2 VCAN	7.64e-05	192	101	5	f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 TTC28 TMEM132C PIEZO2 PCDH15	7.64e-05	192	101	5	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	mild-Lymphocytic-CD4_T_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RASGRP4 LILRB2 ARHGEF40 NAMPT TIMP2	7.64e-05	192	101	5	4cd8f572e067bf5fe22f62fa868d7d332f097a8c
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 SAMD5 TMEM132C PIEZO2 PCDH15	7.64e-05	192	101	5	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	18-Distal-Immune-Hematopoietic,_Macrophage\|Distal / Age, Tissue, Lineage and Cell class	LAT2 LILRB2 IRF5 ARHGAP30 RYR1	7.64e-05	192	101	5	e54577183b09599a3b2bdd532a18ea8f4a6e3524
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LILRB2 SKIL NAMPT TIMP2 VCAN	7.64e-05	192	101	5	0219093e7921a0db78053aee13ec480b520f5662
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 SAMD5 TMEM132C PIEZO2 PCDH15	7.64e-05	192	101	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	BAL-Control-Myeloid-MoAM-MoAM3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LILRB2 PPP1R15A ITGA7 NAMPT VCAN	7.82e-05	193	101	5	837c61408462c519912ecf3b83fdc72cd85fe88f
ToppCell	Control-Myeloid-MoAM3\|Control / Disease group,lineage and cell class （2021.01.30）	LILRB2 PPP1R15A ITGA7 NAMPT VCAN	7.82e-05	193	101	5	97d2f12be43fc26efa84ac4c6119132928a123de
ToppCell	BAL-Control-Myeloid-MoAM-MoAM3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	LILRB2 PPP1R15A ITGA7 NAMPT VCAN	7.82e-05	193	101	5	d81840e1322507552b7726bf7828309375162324
Disease	von Hippel-Lindau disease (implicated_via_orthology)	VHL VHLL	1.07e-05	2	97	2	DOID:14175 (implicated_via_orthology)
Disease	familial erythrocytosis 2 (implicated_via_orthology)	VHL VHLL	1.07e-05	2	97	2	DOID:0060474 (implicated_via_orthology)
Disease	sudden infant death syndrome (implicated_via_orthology)	VHL VHLL	3.20e-05	3	97	2	DOID:9007 (implicated_via_orthology)
Disease	nephroblastoma (biomarker_via_orthology)	VHL VHLL	6.39e-05	4	97	2	DOID:2154 (biomarker_via_orthology)
Disease	Infection	POMC G6PD	2.22e-04	7	97	2	C3714514
Disease	cervical cancer (is_marker_for)	APEX1 MDC1 MMP13	2.27e-04	36	97	3	DOID:4362 (is_marker_for)
Disease	gallbladder neoplasm	CNTN4 ABCB4	3.79e-04	9	97	2	EFO_0004606
Disease	subiculum volume	SAMD5 LHPP VCAN	3.86e-04	43	97	3	EFO_0009399
Disease	alcohol use disorder (implicated_via_orthology)	ERBB2 PSD3 RYR1 ATP1A1 HDAC2	4.72e-04	195	97	5	DOID:1574 (implicated_via_orthology)
Disease	Kunitz-type protease inhibitor 2 measurement	RASGRP4 RYR1	4.73e-04	10	97	2	EFO_0008200
Disease	Ciliopathies	VHL ARL13B PCDH15 CCDC40	4.85e-04	110	97	4	C4277690
Disease	Primary biliary cirrhosis	IRF5 ABCB4 CLEC16A	5.03e-04	47	97	3	C0008312
Disease	hyperhomocysteinemia (biomarker_via_orthology)	ATP1A1 G6PD	6.91e-04	12	97	2	DOID:9279 (biomarker_via_orthology)
Disease	Congenital muscular dystrophy	ITGA7 RYR1	6.91e-04	12	97	2	cv:C0699743
Disease	smoking cessation	CUL3 ZSWIM8 CTTNBP2 C1orf21 PCDH15 KLC1	7.27e-04	325	97	6	EFO_0004319
Disease	Sarcomatoid Renal Cell Carcinoma	VHL ERBB2 POMC RYR1	8.57e-04	128	97	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	VHL ERBB2 POMC RYR1	8.57e-04	128	97	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	VHL ERBB2 POMC RYR1	8.57e-04	128	97	4	C1266044
Disease	Papillary Renal Cell Carcinoma	VHL ERBB2 POMC RYR1	8.57e-04	128	97	4	C1306837
Disease	Renal Cell Carcinoma	VHL ERBB2 POMC RYR1	8.57e-04	128	97	4	C0007134
Disease	Neoplasm of lung	ERBB2 ERCC6	9.49e-04	14	97	2	cv:C0024121
Disease	1-methylurate measurement	CNTN4 PSD3	9.49e-04	14	97	2	EFO_0021173
Disease	Lung cancer	ERBB2 ERCC6	9.49e-04	14	97	2	cv:C0242379
Disease	LUNG CANCER	ERBB2 ERCC6	9.49e-04	14	97	2	211980
Disease	urinary bladder cancer (biomarker_via_orthology)	VHL VHLL	9.49e-04	14	97	2	DOID:11054 (biomarker_via_orthology)
Disease	response to bronchodilator, FEV/FEC ratio	CNTN4 HSDL2 LILRB2 FNBP1L ITGA7 TMEM132C ARNT2 PCDH15 MMP13	9.55e-04	766	97	9	EFO_0004713, GO_0097366
Disease	response to platinum based chemotherapy, magnesium measurement	PSD3 PCDH15	1.09e-03	15	97	2	EFO_0004647, EFO_0004845
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	VHL ERBB2 POMC RYR1	1.47e-03	148	97	4	C0279702
Disease	Congenital Fiber Type Disproportion	ITGA7 RYR1	1.58e-03	18	97	2	C0546264
Disease	cardiomyopathy (implicated_via_orthology)	ERBB2 ITGA7 MYH15	1.67e-03	71	97	3	DOID:0050700 (implicated_via_orthology)
Disease	asthma, response to diisocyanate	COL12A1 CMYA5 RYR1 VCAN MMP13	1.73e-03	261	97	5	EFO_0006995, MONDO_0004979
Disease	stomach cancer (is_implicated_in)	ERBB2 ERCC6 HDAC2	1.74e-03	72	97	3	DOID:10534 (is_implicated_in)
Disease	type 1 diabetes mellitus (is_marker_for)	TIMP2 G6PD HDAC2	1.74e-03	72	97	3	DOID:9744 (is_marker_for)
Disease	Craniofacial Abnormalities	CNTN4 ERCC6 IRF6 MMP13	1.78e-03	156	97	4	C0376634
Disease	Endometrioma	TXNIP BRD8 VCAN HDAC2	2.00e-03	161	97	4	C0269102
Disease	Endometriosis	TXNIP BRD8 VCAN HDAC2	2.00e-03	161	97	4	C0014175
Disease	periodontitis (biomarker_via_orthology)	NAMPT MMP13	2.16e-03	21	97	2	DOID:824 (biomarker_via_orthology)
Disease	Disease Exacerbation	ERBB2 APEX1 ABCB4 TXNIP	2.18e-03	165	97	4	C0235874
Disease	sex interaction measurement, bilirubin measurement	COL12A1 PSD3	2.37e-03	22	97	2	EFO_0004570, EFO_0008343
Disease	Carcinoma of lung	ERBB2 ERCC6	2.59e-03	23	97	2	C0684249
Disease	airway responsiveness measurement	PCDH15 MYH15	2.82e-03	24	97	2	EFO_0006897
Disease	stomach carcinoma (is_marker_for)	ERBB2 MDC1	2.82e-03	24	97	2	DOID:5517 (is_marker_for)
Disease	blood tin measurement	SH2D3C PSD3	3.05e-03	25	97	2	EFO_0021530
Disease	heel bone mineral density, urate measurement	CNTN4 PSD3 CHN2 GLDC	3.11e-03	182	97	4	EFO_0004531, EFO_0009270
Disease	childhood aggressive behaviour measurement	CNTN4 FCHO2 HECTD1	3.19e-03	89	97	3	EFO_0007663

Protein segments in the cluster

Peptide	Gene	Start	Entry
TDEYDGEGNEEQKGP	ABR	26	Q12979
GERQSENYPNKEDVG	ACKR2	366	O00590
DIDETEYHADGGKVP	ERBB2	871	P04626
GEDEENTRSKPEYGT	ESX1	41	Q8N693
TRPNEKGEYEVAEGI	BTBD10	206	Q9BSF8
NAENIPEGYNKGTEE	ALG13	426	Q9NP73
EGQGPATLYQEVDEA	ARHGEF40	751	Q8TER5
VETEADSGQAGPYEN	ARHGEF25	91	Q86VW2
YEPSGEGSGEVDIVD	VCAN	2426	P13611
EADIEPNGKVKYDEF	CALML4	171	Q96GE6
SLEEPKEEDQGEGYL	BRD8	641	Q9H0E9
PDVDEEGYSIKPETN	FCHO2	316	Q0JRZ9
EDYIIEIKPFSDGGD	CNTN4	966	Q8IWV2
ATAKGIQGEYPEDVA	ARL13B	36	Q3SXY8
KVSYGIGDEEHDQEG	APEX1	141	P27695
IKQESGGDGEVEEYL	ERCC6	31	Q03468
IPEEDADVGQGSKYC	ARNT2	296	Q9HBZ2
GGEGVEVLVNEPYEK	PITPNA	36	Q00169
NPDGEGEATKGYLDD	G6PD	311	P11413
GEGEKVDIYFPDESS	AFMID	71	Q63HM1
LGGDYAPDEITDEVQ	KBTBD3	556	Q8NAB2
IKQESGGDGEVEEYL	ERCC6	31	P0DP91
NEDPEGSRITYVKGD	OARD1	6	Q9Y530
KATDPDEGANGDVTY	PCDHGA4	296	Q9Y5G9
DEYVVTDPEQEKNFG	MDC1	1966	Q14676
PPADYNKEITEGDEV	FXR2	61	P51116
DTVVLAQGKDGEYEE	PPFIBP1	341	Q86W92
EETFGYEVPIKEEGD	MLEC	106	Q14165
GRDKYEPAAVSEQGD	ATP1A1	6	P05023
DPEDGETIYAQKFQG	IGHV1-24	71	A0A0C4DH33
GDVAEVLYQAEDPGD	PLXNB3	146	Q9ULL4
EEDFPGIGDKVDAVY	MMP13	421	P45452
DDEEDLGIYVGEVNP	PDZD4	151	Q76G19
KNYDPEGRGTISQED	RASGRP4	476	Q8TDF6
PVKVYPNGAEDESAE	POMC	156	P01189
GGEEEDQPIYLAVKG	NENF	56	Q9UMX5
LYAAVKDTQPEDGVE	LILRB2	531	Q8N423
EEGIENFDVYAIKPG	HSDL2	251	Q6YN16
PEVKADGYVDNLAEA	LHPP	246	Q9H008
TGKYTEGVDEADPAK	IRF5	71	Q13568
GKPDGVNYIRTDEEG	JAM3	286	Q9BX67
DPEDGETIYAEKFQG	IGHV1-69-2	71	A0A0G2JMI3
PYVEEDGSKNDDRAG	MED30	116	Q96HR3
YDPDEGTINIDGQDI	ABCB4	446	P21439
ATDIDDGPNGQIEYV	PCDH15	176	Q96QU1
DGEKADISANVYPDI	CHN2	331	P52757
RPIGEQEEEEYETKG	HECTD1	1741	Q9ULT8
EGEVLYIIEEDKGDG	FNBP1L	561	Q5T0N5
YKEAAGDDEVTVVEP	COL12A1	666	Q99715
VGEIEPSNYGSDDLE	CTTNBP2	976	Q8WZ74
EEGEGKNPVDYIQGL	CUL3	331	Q13618
EEQKGVYGEGESVDH	CMYA5	3296	Q8N3K9
QELPGEEAYDSVSGE	CCDC40	121	Q4G0X9
NGDVFGDEYRIKPVE	C1orf21	26	Q9H246
KVEYTLGEESEAPGQ	EIF4G1	1421	Q04637
LDDGPYEAGGEKEQD	ITGA7	241	Q13683
QQGEYGEFVIKDPDE	ETV3L	61	Q6ZN32
DGIDDESYGQIFKPI	HDAC2	231	Q92769
DEEEDFENVGKVGSP	RSF1	1346	Q96T23
YGEESEEERGLEPGK	CHGB	401	P05060
GLYITEQPEDDDVKG	RYR1	4686	P21817
LDEEGKGAVYSFDPV	PSMB1	141	P20618
KGPEDYPEEGVEESS	ERCC6L	1121	Q2NKX8
YPEEGVEESSGEASK	ERCC6L	1126	Q2NKX8
NVDVVKYESGPDGGE	KLC1	526	Q07866
EGVAEEEGVNKFSYP	PPP1R15A	166	O75807
PEREEVGAGYNSEDE	OTUD5	166	Q96G74
AKGVEEPGGDEYTDE	ARHGAP30	731	Q7Z6I6
AVETGKYQEGVDDPD	IRF6	61	O14896
EEDGEPDYVNGEVAA	LAT2	226	Q9GZY6
YEVAIDGKEEDLGSP	SMG8	456	Q8ND04
VEEKPDVTYSDVGGC	PSMC2	166	P35998
ENDGYIEEGSITKHP	SCML1	241	Q9UN30
DYGEAPVETDGEHVK	SKIL	56	P12757
SSPGGDYEEDEIKNH	TMEM132C	806	Q8N3T6
GYDDLEVCKQIGDPD	SAMD5	26	Q5TGI4
ANYEEDENGDITPIK	MPHOSPH6	136	Q99547
IPDGENAYIEAEVKG	MYH15	56	Q9Y2K3
VTLEEGKGDLEEYGQ	NAMPT	441	P43490
EGVDIKNGTEDLPYA	NSDHL	151	Q15738
LEAQAGTQEAGPEEY	VHLL	11	Q6RSH7
EGEYVPVEGDEVTYK	CARHSP1	96	Q9Y2V2
PNYKNVGEEEDEEKG	CLEC16A	391	Q2KHT3
ELKRDYVDEQTGDGP	VPS50	566	Q96JG6
VPKGPVEGYEENEEF	TRMT112	66	Q9UI30
DNKFGVEQPEGDEDL	POLR2A	161	P24928
IKDDYGPESRGFVEN	POLR2A	811	P24928
SEKEVDSGNDIYGNP	TIMP2	51	P16035
EPGEEKLEGYSEKAQ	PIEZO2	861	Q9H5I5
AEVGAEEAGVEEYGP	VHL	11	P40337
KGVDANPVETYDSGD	ZNF609	11	O15014
KPEADGDSEYGEEPI	ZNF609	526	O15014
VYEVSVPGDDKDAGP	ZNF710	121	Q8N1W2
VAVPFDDDDKIVGGY	PRSS3	71	P35030
KEVEAGPGDQQGDSY	WDR62	961	O43379
GYKEETVCEVGPDGV	TMEM81	56	Q6P7N7
KEAAPAVGEEDDDYQ	ZSWIM8	716	A7E2V4
RPAGNKDEEEYEGFS	TTC28	2046	Q96AY4
ERAAGEPEAGSDYVK	SH2D3C	171	Q8N5H7
ADITDKGEVPDGYVV	TRBV10-2	71	A0A0K0K1G8
GEPEDYGRTSETQEK	TCHHL1	351	Q5QJ38
EVVFNDPEKVYGSGE	TXNIP	11	Q9H3M7
VKGEDEDILGPGYTE	PSD3	421	Q9NYI0
GVLFQYPDTEGKVED	GLDC	261	P23378
GEPRNYGLTDEEKAE	AK7	606	Q96M32