Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TLK2 STK32C PDPK2P PAK6 NEK9 ARAF AATK MAST4 MYLK3 CDK13 MARK4 SRPK3 WNK4 DYRK2

3.57e-0544617314GO:0004674
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

SHANK1 NLRP12 MYBBP1A MAPT DVL2 BLNK TRIM31 MED1 CBFA2T3 ARID1A RETREG3 LPIN3 GAS2L1 WTIP TRIM28 RPTOR MARK4 TONSL FGA SYN1 IRS2 NR0B2 MED13 HR

6.53e-05116017324GO:0030674
GeneOntologyMolecularFunctionprotein kinase activity

TLK2 TNK1 STK32C PDPK2P PAK6 NEK9 ARAF AATK MAST4 MYLK3 TRIM28 CDK13 MARK4 SRPK3 WNK4 DYRK2

6.97e-0560017316GO:0004672
GeneOntologyMolecularFunctionprotein serine kinase activity

TLK2 STK32C PAK6 NEK9 ARAF AATK MAST4 CDK13 MARK4 SRPK3 WNK4 DYRK2

8.03e-0536317312GO:0106310
GeneOntologyMolecularFunctionmicrotubule binding

SGIP1 KIF26A MAPT KIF26B CAMSAP3 KIF12 EML3 GAS2L1 RMDN1 MARK4 MTCL1

8.09e-0530817311GO:0008017
GeneOntologyMolecularFunctiontubulin binding

SGIP1 KIF26A MAPT KIF26B BCAS3 CAMSAP3 KIF12 AGBL5 EML3 GAS2L1 RMDN1 MARK4 MTCL1

9.51e-0542817313GO:0015631
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TLK2 TNK1 STK32C PDPK2P PAK6 NEK9 ARAF AATK MAST4 MYLK3 TRIM28 CDK13 MARK4 ETNK1 SRPK3 WNK4 DYRK2

1.50e-0470917317GO:0016773
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

MED1 NR0B2 MED13 HR

2.06e-04341734GO:0046966
GeneOntologyMolecularFunctionprotein kinase binding

PITPNM2 MAPT DVL2 BLNK TNS2 SRCIN1 PDPK2P NEK9 INKA2 CRY2 LIME1 LMNB1 CADPS CDK13 RPTOR PKD1 SYN1 IRS2 GPRC5B

2.11e-0487317319GO:0019901
GeneOntologyMolecularFunctionmolecular adaptor activity

SHANK1 NLRP12 MYBBP1A MAPT DVL2 BLNK TRIM31 MED1 CBFA2T3 ARID1A RETREG3 LPIN3 GAS2L1 WTIP TRIM28 RPTOR MARK4 TONSL EIF4G1 FGA SYN1 IRS2 NR0B2 MED13 HR

2.76e-04135617325GO:0060090
GeneOntologyMolecularFunctionkinase binding

MYCN PITPNM2 MAPT DVL2 BLNK TNS2 SRCIN1 PDPK2P NEK9 INKA2 CRY2 LIME1 LMNB1 CADPS CDK13 RPTOR PKD1 SYN1 IRS2 GPRC5B

2.87e-0496917320GO:0019900
GeneOntologyMolecularFunctionkinase activity

TLK2 TNK1 STK32C PDPK2P PAK6 NEK9 ARAF AATK MAST4 MYLK3 TRIM28 CDK13 MARK4 ETNK1 SRPK3 WNK4 DYRK2

3.58e-0476417317GO:0016301
GeneOntologyMolecularFunctionnuclear vitamin D receptor binding

MED1 MED13 HR

4.74e-04181733GO:0042809
GeneOntologyMolecularFunctioncytoskeletal anchor activity

GAS2L1 MARK4 SYN1

1.13e-03241733GO:0008093
GeneOntologyMolecularFunctionnuclear receptor binding

BCAS3 MED1 ARID1A CRY2 NR0B2 MED13 HR

1.25e-031871737GO:0016922
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TLK2 TNK1 SGIP1 STK32C PDPK2P PAK6 NEK9 ARAF AATK MAST4 MYLK3 TRIM28 CDK13 MARK4 ETNK1 SRPK3 WNK4 DYRK2

1.34e-0393817318GO:0016772
GeneOntologyMolecularFunctionenzyme activator activity

NLRP12 BCAS3 TBC1D5 SIPA1L3 PDPK2P GMIP NEK9 RGS12 RIN1 TBC1D10B GTF2F1 RPTOR DMWD GPRC5B

1.76e-0365617314GO:0008047
GeneOntologyMolecularFunctionchromatin binding

BCAS3 MLLT10 MED1 CBFA2T3 MBD6 ARID1A REPIN1 SCML4 ZNF750 YBX2 GTF2F1 TRIM28 ATOH1 KDM6A HR

1.98e-0373917315GO:0003682
GeneOntologyMolecularFunctionleukotriene C4 gamma-glutamyl transferase activity

GGT6 GGT5

2.02e-0381732GO:0103068
GeneOntologyCellularComponentmicrotubule

SLAIN2 KIF26A MAPT KIF26B BCAS3 CAMSAP3 KIF12 RUSC1 NCKAP5L BOD1L2 EML3 GAS2L1 RADIL RMDN1 MTCL1 DYNC1LI2

8.96e-0653317216GO:0005874
GeneOntologyCellularComponentmicrotubule end

SLAIN2 CAMSAP3 NCKAP5L GAS2L1

2.63e-04381724GO:1990752
DomainPROTEIN_KINASE_ATP

TLK2 TNK1 STK32C PAK6 NEK9 ARAF AATK MAST4 MYLK3 CDK13 MARK4 SRPK3 WNK4 DYRK2

8.18e-0545917014PS00107
DomainSer/Thr_kinase_AS

TLK2 STK32C PAK6 NEK9 ARAF MAST4 MYLK3 CDK13 MARK4 SRPK3 WNK4 DYRK2

1.08e-0435717012IPR008271
DomainS_TKc

TLK2 STK32C PAK6 NEK9 ARAF MAST4 MYLK3 CDK13 MARK4 SRPK3 WNK4 DYRK2

1.14e-0435917012SM00220
DomainPROTEIN_KINASE_ST

TLK2 STK32C PAK6 NEK9 ARAF MAST4 MYLK3 CDK13 MARK4 SRPK3 WNK4 DYRK2

1.23e-0436217012PS00108
DomainKinase-like_dom

TLK2 TNK1 STK32C PAK6 NEK9 ARAF AATK MAST4 MYLK3 CDK13 MARK4 ETNK1 SRPK3 WNK4 DYRK2

1.34e-0454217015IPR011009
DomainProt_kinase_dom

TLK2 TNK1 STK32C PAK6 NEK9 ARAF AATK MAST4 MYLK3 CDK13 MARK4 SRPK3 WNK4 DYRK2

1.59e-0448917014IPR000719
DomainPROTEIN_KINASE_DOM

TLK2 TNK1 STK32C PAK6 NEK9 ARAF AATK MAST4 MYLK3 CDK13 MARK4 SRPK3 WNK4 DYRK2

1.73e-0449317014PS50011
DomainPkinase

TLK2 STK32C PAK6 NEK9 ARAF MAST4 MYLK3 CDK13 MARK4 SRPK3 WNK4 DYRK2

1.98e-0438117012PF00069
DomainPDZ

SHANK1 SIPA1L3 DVL2 PARD6G RGS12 RADIL MAST4

3.11e-041411707PF00595
DomainPDZ

SHANK1 SIPA1L3 DVL2 PARD6G RGS12 RADIL MAST4

4.17e-041481707SM00228
Domain-

SHANK1 SIPA1L3 DVL2 PARD6G RGS12 RADIL MAST4

4.52e-0415017072.30.42.10
DomainPDZ

SHANK1 SIPA1L3 DVL2 PARD6G RGS12 RADIL MAST4

4.71e-041511707PS50106
DomainDEK_C

SSH1 SSH3

4.88e-0441702PF08766
DomainDEK_C

SSH1 SSH3

4.88e-0441702IPR014876
DomainPDZ

SHANK1 SIPA1L3 DVL2 PARD6G RGS12 RADIL MAST4

4.90e-041521707IPR001478
DomainProtein_kinase_ATP_BS

TLK2 TNK1 STK32C PAK6 ARAF AATK MYLK3 CDK13 MARK4 SRPK3 DYRK2

7.23e-0437917011IPR017441
DomainNUT

NUTM2G NUTM2F

8.09e-0451702IPR024310
DomainNUT_N

NUTM2G NUTM2F

8.09e-0451702IPR024309
DomainNUT

NUTM2G NUTM2F

8.09e-0451702PF12881
DomainLNS2

PITPNM2 LPIN3

1.21e-0361702IPR013209
DomainIRO

IRX5 IRX1

1.21e-0361702SM00548
DomainLNS2

PITPNM2 LPIN3

1.21e-0361702SM00775
DomainRBD

ARAF RGS12

1.21e-0361702PF02196
DomainIroquois_homeo

IRX5 IRX1

1.21e-0361702IPR003893
DomainLNS2

PITPNM2 LPIN3

1.21e-0361702PF08235
DomainLNS2/PITP

PITPNM2 LPIN3

1.21e-0361702IPR031315
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PITPNM2 RNF223 DGCR2 CRYBG2 HIVEP2 KIF26A BCAS3 INPP5E SIPA1L3 RTTN PPP6R1 STK32C MLLT10 MBD6 ARID1A HES2 REPIN1 EML3 REXO1 MICALL1 LPIN3 GAS2L1 LIME1 RADIL AATK SCAP CELSR2 GAREM2 SSH1 TRIM28 CDK13 RPTOR KANK3 ZNF516 MARK4 EIF4G1 PKD1 IRS2 DMWD MED13 ELL ATPAF2 HR

8.65e-2611051774335748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SLAIN2 TNK1 HIVEP2 MAPT KIF26B BCAS3 INPP5E TBC1D5 SIPA1L3 CAMSAP3 STK32C PAK6 NCKAP5L NEK9 GLCCI1 ARAF RGS12 PPM1H MICALL1 LPIN3 TBC1D10B RADIL MAST4 MYLK3 RPTOR MARK4 EIF4G1 FAM53B SRPK3 IRS2 MTCL1 TSC22D4 MEX3B WNK4 DYRK2

1.38e-218611773536931259
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 TLK2 CACNA1A MYBBP1A NYAP2 SGIP1 HCN4 PRR36 TBC1D5 SIPA1L3 CAMSAP3 DVL2 TRIOBP PPP6R1 NEK9 PPM1H CELSR2 LMNB1 SSH1 WTIP TRIM28 RPTOR ZNF516 EIF4G1 SYN1 MTCL1 PRRC2A

6.68e-139631772728671696
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TLK2 MYCN MYBBP1A MAPT CAMSAP3 MED1 REXO1 MICALL1 TBC1D10B RBMXL2 SSH1 TRIM28 CDK13 RPTOR ZNF516 EIF4G1 IRS2 DMWD KLHDC4 KDM6A PRRC2A MED13 DYNC1LI2

1.24e-117741772315302935
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

MYBBP1A PDE4D CAMSAP3 MED1 GLCCI1 ARAF RIN1 GTF2F1 TRIM28 CDK13 RPTOR SSH3 EIF4G1 MPLKIP IRS2 MTCL1 PRRC2A DYNC1LI2

1.27e-105031771816964243
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A SGIP1 MAPT BCAS3 CAMSAP3 SRCIN1 PDPK2P GLCCI1 RIN1 RADIL AMER2 RPTOR SYN1 PRRC2A DYNC1LI2

3.62e-103471771517114649
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PITPNM2 SLAIN2 DGCR2 NYAP2 KIF26A INPP5E RNF44 TRIOBP SRCIN1 KIAA1614 MICALL1 MAST4 RPTOR ZNF516 FAM53B MED13

1.53e-085291771614621295
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SHANK1 CACNA1A PITPNM2 MYBBP1A PDE4D SGIP1 PRR36 MAPT BCAS3 SIPA1L3 RBP3 CAMSAP3 GJC2 SRCIN1 ARID1A GAS2L1 RIN1 CADPS TRIM28 RPTOR EIF4G1 FGA SYN1 TSC22D4 PRRC2A

7.87e-0814311772537142655
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

PITPNM2 SLAIN2 BCAS3 TBC1D5 DVL2 PPP6R1 GMIP NCKAP5L NEK9 GLCCI1 ARAF CRY2 LPIN3 GTF2F1 RPTOR MPLKIP FAM53B IRS2 DMWD

1.64e-0610381771926673895
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SGIP1 MAPT GJC2 SRCIN1 AMER2 LMNB1 FGA SYN1 PRRC2A

3.13e-06231177916452087
Pubmed

A genome-wide association study of early menopause and the combined impact of identified variants.

NYAP2 SGIP1 PRRC2A

4.47e-067177323307926
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SLAIN2 MAPT DVL2 PPP6R1 MSI1 ARID1A NCKAP5L BOD1L2 ZC3H3 REPIN1 ARAF TBC1D10B ZNF469 CADPS TRIM28 RPTOR MARK4 IRS2 SIGLEC1

4.67e-0611161771931753913
Pubmed

Sidekick 2 directs formation of a retinal circuit that detects differential motion.

HCN4 TH SYN1 SDK1

5.32e-0623177426287463
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SHANK1 CACNA1A PITPNM2 NYAP2 SGIP1 HCN4 MAPT BCAS3 CAMLG CAMSAP3 DVL2 TRIOBP SRCIN1 PPP6R1 AMER2 CELSR2 CADPS TRIM28 RPTOR

6.23e-0611391771936417873
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

TLK2 SLAIN2 MYBBP1A PDE4D SIPA1L3 TRIOBP ARID1A NEK9 GLCCI1 EML3 CRY2 GTF2F1 LMNB1 TRIM28 EIF4G1 FGA MTCL1 COG5 DYNC1LI2

7.59e-0611551771920360068
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

MYCN MYBBP1A HIVEP2 TRIM31 MLLT10 MED1 TBX18 GTF2F1 VENTX TRIM28 TONSL ATOH1 TSC22D4 NR0B2 ELL HR

1.18e-058771771620211142
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

BCAS3 TNS2 CPT2 RIN1 SSH3 IRS2 KDM6A SDK1

1.51e-05214177822199357
Pubmed

Dbh+ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart.

HCN4 TBX18 TH

1.51e-0510177338016975
Pubmed

Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons.

MAPT TH ATOH1

1.51e-0510177319940179
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXE1 MYCN HIVEP2 IRX5 FOSB KLF15 IRX1 HES2 ZC3H3 TBX18 VENTX NKX6-3 DBX1 ATOH1 TSC22D4 FOXL1

1.80e-059081771619274049
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

FOXE1 CRYBG2 PDE4D TMC2 BCAS3 PAK6 PMEPA1 PPM1H RADIL AATK FAM53B SDK1 GPRC5B FOXL1 HR

1.99e-058141771523251661
Pubmed

Math1 is essential for the development of hindbrain neurons critical for perinatal breathing.

MAPT TH ATOH1

2.08e-0511177319914183
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

TNK1 DNAAF9 STK32C PAK6 NEK9 ARAF MYLK3 SRPK3 WNK4 DYRK2

2.30e-053721771022939624
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

SGIP1 CAMSAP3 SRCIN1 AMER2 TRIM28

2.41e-0567177529254152
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

FOXE1 MYCN MEF2B IRX5 FOSB KLF15 IRX1 HES2 TBX18 VENTX NKX6-3 ATOH1

2.48e-055441771228473536
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PITPNM2 PDE4D HIVEP2 MAPT BCAS3 TBC1D5 SIPA1L3 CAMSAP3 BLNK TRIOBP SRCIN1 STK32C ARID1A NEK9 PPM1H INKA2 CDK13 RPTOR SCNN1A TSC22D4 KDM6A

2.49e-0514891772128611215
Pubmed

Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse.

RBMXL3 RBMXL2

2.58e-052177218562473
Pubmed

Synapsin-1 and tau reciprocal O-GlcNAcylation and phosphorylation sites in mouse brain synaptosomes.

MAPT SYN1

2.58e-052177223807304
Pubmed

Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.

CACNA1A MAPT

2.58e-052177224849348
Pubmed

An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning.

RBMXL3 RBMXL2

2.58e-052177230674417
Pubmed

AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease.

INPP5E PKD1

2.58e-052177231625572
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYBBP1A TBC1D5 SIPA1L3 CAMSAP3 TRIOBP TNS2 PPP6R1 ARID1A NCKAP5L PPM1H TBC1D10B GTF2F1 SSH1 SSH3 DMWD KDM6A PRRC2A

2.83e-0510491771727880917
Pubmed

Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization.

PRR36 DVL2 NEK9

4.53e-0514177334674267
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

INPP5E SRCIN1 TRIM28 MARK4 SYN1 DMWD

6.15e-05132177616944949
Pubmed

KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m6A reader YTHDC1 protein degradation.

MYCN TRIM28

7.70e-053177238745192
Pubmed

Regionally restricted expression of the transcription factor c-myc intron 1 binding protein during brain development.

MYCN HIVEP2

7.70e-053177214624490
Pubmed

Neuroblastoma patient-derived cultures are enriched for a mesenchymal gene signature and reflect individual drug response.

MYCN TH

7.70e-053177232777141
Pubmed

Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin.

SSH1 SSH3

7.70e-053177214531860
Pubmed

Deletion of Aurora kinase A prevents the development of polycystic kidney disease in mice.

INPP5E PKD1

7.70e-053177238191531
Pubmed

Downregulation of Foxe1 by HR suppresses Msx1 expression in the hair follicles of Hr(Hp) mice.

FOXE1 HR

7.70e-053177221777520
Pubmed

Claudin-7 Modulates Cl- and Na+ Homeostasis and WNK4 Expression in Renal Collecting Duct Cells.

SCNN1A WNK4

7.70e-053177231382627
Pubmed

Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease.

MAPT MSI1

7.70e-053177230367664
Pubmed

Loss of polarity protein AF6 promotes pancreatic cancer metastasis by inducing Snail expression.

FOXE1 DVL2

7.70e-053177226013125
Pubmed

Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.

ARAF SYN1

7.70e-05317727568108
Pubmed

Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk.

ZNF750 RPTOR

7.70e-053177224005976
Pubmed

TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy.

TRIM28 KDM6A

7.70e-053177236935008
Pubmed

Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.

CACNA1A TH

7.70e-053177232154672
Pubmed

Tau oligomers mediate aggregation of RNA-binding proteins Musashi1 and Musashi2 inducing Lamin alteration.

MSI1 LMNB1

7.70e-053177231532069
Pubmed

Abnormal expression of tyrosine hydroxylase immunoreactivity in cerebellar cortex of ataxic mutant mice.

CACNA1A TH

7.70e-053177210350535
Pubmed

Alternating array of tyrosine hydroxylase and heat shock protein 25 immunopositive Purkinje cell stripes in zebrin II-defined transverse zone of the cerebellum of rolling mouse Nagoya.

CACNA1A TH

7.70e-053177220462503
Pubmed

RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction.

MAPT MSI1

7.70e-053177232855391
Pubmed

The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia.

IRX5 IRX1

7.70e-053177235328612
Pubmed

TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.

MAPT TRIM28

7.70e-053177227779468
Pubmed

Conserved role of ATP synthase in mammalian cilia.

PKD1 ATPAF2

7.70e-053177233639177
Pubmed

Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly.

MED1 GTF2F1

7.70e-053177222343046
Pubmed

Phosphoproteomic analysis of synaptosomes from human cerebral cortex.

MAPT SRCIN1 SYN1

8.36e-0517177315822905
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TBC1D5 SIPA1L3 PPP6R1 ARID1A NCKAP5L ARAF PPM1H RADIL IRS2 MTCL1

1.04e-044461771024255178
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

NYAP2 SIPA1L3 DVL2 SRCIN1 PPP6R1 NCKAP5L NEK9

1.34e-04218177733378226
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TLK2 MYBBP1A INPP5E CAMSAP3 MED1 NCKAP5L NEK9 GLCCI1 ARAF PPM1H MICALL1 DNAAF2 LPIN3 RIN1 RPTOR FAM53B DYNC1LI2 DYRK2

1.50e-0413211771827173435
Pubmed

ATP release into ADPKD cysts via pannexin-1/P2X7 channels decreases ENaC activity.

PKD1 SCNN1A

1.53e-044177230952430
Pubmed

PDK1-AKT signaling pathway regulates the expression and function of cardiac hyperpolarization-activated cyclic nucleotide-modulated channels.

HCN4 PDPK2P

1.53e-044177232184125
Pubmed

Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/β-catenin signaling through blocking autophagic degradation of dishevelled2.

DVL2 IRS2

1.53e-044177224616100
Pubmed

Differential timing of granule cell production during cerebellum development underlies generation of the foliation pattern.

MAPT ATOH1

1.53e-044177227609139
Pubmed

Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.

MAPT TRIM28

1.53e-044177229863470
Pubmed

Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.

MSI1 EIF4G1

1.53e-044177218490513
Pubmed

ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4PHAII mice.

SCNN1A WNK4

1.53e-044177228365586
Pubmed

The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes.

SSH1 SSH3

1.53e-044177217848544
Pubmed

14-3-3zeta/tau heterodimers regulate Slingshot activity in migrating keratinocytes.

MAPT SSH1

1.53e-044177219371722
Pubmed

SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation.

MAPT SSH1

1.53e-044177233044112
Pubmed

Atoh1-dependent rhombic lip neurons are required for temporal delay between independent respiratory oscillators in embryonic mice.

DBX1 ATOH1

1.53e-044177224842997
Pubmed

Beyond conventional chemotherapy: Emerging molecular targeted and immunotherapy strategies in urothelial carcinoma.

ARID1A KDM6A

1.53e-044177226138514
Pubmed

Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia.

HCN4 TBX18

1.53e-044177223455426
Pubmed

Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma.

ATOH1 KDM6A

1.53e-044177233253789
Pubmed

Increased hippocampal excitability and impaired spatial memory function in mice lacking VGLUT2 selectively in neurons defined by tyrosine hydroxylase promoter activity.

MAPT TH

1.53e-044177224802380
Pubmed

SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1.

SCAP RPTOR

1.53e-044177230530672
Pubmed

TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells.

PKD1 ATOH1

1.53e-044177215483558
Pubmed

Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes.

IRX5 IRX1

1.53e-044177211435706
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

TNK1 SIPA1L3 ARAF FAM53B IRS2

1.80e-04102177515778465
Pubmed

Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.

DVL2 PDPK2P PKD1

1.86e-0422177327582005
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

TLK2 CACNA1A MYBBP1A KIF26A BCAS3 PERM1 NEK9

2.02e-04233177737704626
Pubmed

A human MAP kinase interactome.

SHANK1 HIVEP2 KIF26A KIF26B STK32C PAK6 NCKAP5L ARAF TRIM28 COG5

2.09e-044861771020936779
Pubmed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

TNK1 PARD6G NEK9 ARAF AATK LMNB1 TRIM28 CDK13 MTCL1

2.30e-04401177925852190
Pubmed

Iroquois genes influence proximo-distal morphogenesis during rat lung development.

IRX5 IRX1

2.55e-045177216299054
Pubmed

A draft map of the human proteome.

PERM1 LIME1

2.55e-045177224870542
Pubmed

Targeted insertion of the Cre-recombinase gene at the phenylethanolamine n-methyltransferase locus: a new model for studying the developmental distribution of adrenergic cells.

HCN4 TH

2.55e-045177215517585
Pubmed

Expression of two novel mouse Iroquois homeobox genes during neurogenesis.

IRX5 IRX1

2.55e-045177210704856
Pubmed

The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis.

PDPK2P RPTOR

2.55e-045177234646383
Pubmed

Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss.

RPTOR ATOH1

2.55e-045177230247156
Pubmed

Detailed genetic mapping of the A-raf proto-oncogene on the mouse X chromosome.

ARAF SYN1

2.55e-04517722011396
Pubmed

WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination.

SCNN1A WNK4

2.55e-045177223594824
Pubmed

Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR.

RPTOR IRS2

2.55e-045177219561084
Pubmed

Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1.

IRS2 NR0B2

2.55e-045177221081708
Pubmed

Misexpression of Gbx2 throughout the mesencephalon by a conditional gain-of-function transgene leads to deletion of the midbrain and cerebellum in mice.

TH ATOH1

2.55e-045177219603509
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

MYBBP1A MAPT SRCIN1 GMIP AMER2 SYN1 KDM6A

2.81e-04246177715345747
Pubmed

Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network.

MYCN MED1 MED13

3.09e-0426177334506481
Pubmed

Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1.

MAPT TH ATOH1

3.46e-0427177320080794
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

INPP5E EML3 ARAF RGS12 MICALL1 RADIL IRS2

3.49e-04255177715324660
Pubmed

Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.

MAPT MARK4

3.81e-046177223666762
Pubmed

Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis.

TRIOBP DYRK2

3.81e-046177231815665
Pubmed

hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation.

GTF2F1 ELL

3.81e-046177210490622
InteractionTOP3B interactions

MYCN PITPNM2 RNF223 DGCR2 CRYBG2 HIVEP2 KIF26A BCAS3 INPP5E SIPA1L3 RTTN DVL2 PPP6R1 STK32C MLLT10 MBD6 ARID1A HES2 REPIN1 EML3 REXO1 MICALL1 LPIN3 GAS2L1 LIME1 RADIL AATK SCAP CELSR2 GAREM2 SSH1 TRIM28 RMDN1 CDK13 RPTOR KANK3 ZNF516 MARK4 EIF4G1 PKD1 IRS2 DMWD PRRC2A MEX3B MED13 ELL FOXL1 ATPAF2 HR

6.43e-17147017449int:TOP3B
InteractionYWHAH interactions

SLAIN2 TNK1 EVC2 HIVEP2 MAPT KIF26B BCAS3 INPP5E TBC1D5 SIPA1L3 CAMSAP3 KLF15 PARD6G TNS2 PAK6 MED1 NCKAP5L GLCCI1 EML3 ARAF RGS12 PPM1H MICALL1 LPIN3 RIN1 TBC1D10B RADIL MAST4 SSH1 RPTOR MARK4 EIF4G1 FAM53B IRS2 MTCL1 TSC22D4 DMWD MEX3B

1.49e-13110217438int:YWHAH
InteractionYWHAE interactions

MYCN TNK1 HIVEP2 MAPT KIF26B INPP5E TBC1D5 SIPA1L3 CAMSAP3 DVL2 PARD6G TNS2 SRCIN1 PAK6 MBD6 NCKAP5L GLCCI1 ARAF RGS12 PPM1H MICALL1 CRY2 LPIN3 ZNF750 RIN1 RADIL MAST4 LMNB1 SSH1 TRIM28 CDK13 RPTOR MARK4 SYN1 FAM53B IRS2 DMWD PRRC2A MEX3B

1.78e-12125617439int:YWHAE
InteractionYWHAB interactions

MYCN SLAIN2 TNK1 MAPT KIF26B INPP5E TBC1D5 SIPA1L3 CAMSAP3 DVL2 TNS2 PAK6 NCKAP5L GLCCI1 EML3 ARAF RGS12 PPM1H MICALL1 LPIN3 RIN1 TH TBC1D10B RADIL MAST4 LMNB1 SSH1 MARK4 EIF4G1 FAM53B IRS2 MTCL1 DMWD MEX3B

7.72e-12101417434int:YWHAB
InteractionYWHAG interactions

MYCN SLAIN2 TNK1 HIVEP2 MAPT KIF26B BCAS3 INPP5E TBC1D5 SIPA1L3 CAMSAP3 DVL2 TNS2 PAK6 NCKAP5L GLCCI1 EML3 ARAF RGS12 PPM1H MICALL1 LPIN3 RIN1 TBC1D10B RADIL MAST4 SSH1 RPTOR MARK4 EIF4G1 FAM53B IRS2 MTCL1 TSC22D4 DMWD MEX3B

1.20e-10124817436int:YWHAG
InteractionYWHAZ interactions

TLK2 MYCN TNK1 PDE4D HIVEP2 MAPT KIF26B INPP5E TBC1D5 SIPA1L3 CAMSAP3 PARD6G PAK6 ARID1A NCKAP5L GLCCI1 EML3 ARAF RGS12 PPM1H MICALL1 LPIN3 RIN1 TH RADIL MAST4 SSH1 RPTOR SSH3 MARK4 SYN1 FAM53B IRS2 TSC22D4 DMWD PRRC2A MEX3B

1.38e-10131917437int:YWHAZ
InteractionYWHAQ interactions

MYCN TNK1 HIVEP2 MAPT KIF26B TBC1D5 SIPA1L3 CAMSAP3 DVL2 TRIM31 PAK6 MED1 NCKAP5L GLCCI1 EML3 ARAF RGS12 PPM1H CRY2 LPIN3 TH MAST4 LMNB1 SSH1 TRIM28 RPTOR EIF4G1 FGA FAM53B IRS2 DMWD WNK4

1.87e-09111817432int:YWHAQ
Cytoband16q24

CBFA2T3 ZNF469 FOXL1

3.62e-0517176316q24
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CACNA1A MEF2B PRR36 CAMSAP3 GMIP ZNF414 REXO1 CCDC194 GTF2F1 ZNF358 KANK3 ELL

6.50e-0579717612chr19p13
GeneFamilyPDZ domain containing

SHANK1 SIPA1L3 DVL2 PARD6G RGS12 RADIL MAST4

3.76e-0515210971220
GeneFamilySlingshot protein phosphatases

SSH1 SSH3

1.08e-0431092898
ToppCell5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYCN CACNA1A SGIP1 SRCIN1 CADPS SRPK3 MEX3B NR0B2

2.76e-071621768478cf560ef33c5c324142c76417447d4a571a2c9
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NYAP2 ARPP21 TMC2 MAPT SCML4 AMER2 CADPS GPR149

7.27e-071841768571136c832cb8c08457744152231537aa8e8abd7
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 NCKAP5L PMEPA1 CELSR2 CDK13 IRS2 PRRC2A HR

7.89e-071861768bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 NCKAP5L PMEPA1 CELSR2 CDK13 IRS2 PRRC2A HR

8.90e-071891768965e0e388251e7318f8b463816dc96ccb4658677
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYCN ARPP21 SGIP1 KIF26A MAPT SRCIN1 AMER2 TMEM108

1.00e-061921768fe9297cb65234d9f511bab1a5dbf2679d5a4cd15
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26B SRCIN1 PMEPA1 MICALL1 YBX2 SCNN1A WNK4 GPRC5B

1.04e-061931768536b277d90070c4571c592a3c6323b4bf4819f67
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYCN ARPP21 SGIP1 KIF26A MAPT SRCIN1 AMER2 TMEM108

1.04e-061931768a189d46c39067b717509cd144e0225cc93d7731d
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

PDE4D BCAS3 TBC1D5 SIPA1L3 GLCCI1 COG5 KDM6A SDK1

1.26e-0619817681996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

PITPNM2 PDE4D CAMSAP3 GLCCI1 MAST4 SCNN1A NR0B2

3.96e-061631767e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRYBG2 IRX1 STK32C SCNN1A FAM53B TMEM108 ELL

4.13e-061641767fe11fcce4ba7f44ba2989ea3705916b67e75f8e7
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRYBG2 IRX1 STK32C SCNN1A FAM53B TMEM108 ELL

4.13e-061641767b6beb8548ac0dd07e8a580a938e5ee4bf25a3c1f
ToppCellEndothelial-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

MYCN KIF26A PARD6G GJC2 GGT5 KANK3 GPRC5B

4.30e-061651767b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCellEndothelial-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MYCN SGIP1 PARD6G GJC2 RADIL KANK3 GPRC5B

5.03e-06169176795c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PITPNM2 PDE4D SRCIN1 GLCCI1 MAST4 SCNN1A TMEM108

5.23e-061701767a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 NYAP2 SGIP1 MAPT CBFA2T3 CCDC194

6.50e-061151766ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 NYAP2 SGIP1 MAPT CBFA2T3 CCDC194

6.50e-0611517667a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 NYAP2 SGIP1 MAPT CBFA2T3 CCDC194

6.50e-061151766c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

KIF26B TBC1D5 SIPA1L3 ARID1A PPM1H SDK1 MED13

9.41e-061861767de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

KIF26B TBC1D5 SIPA1L3 ARID1A PPM1H SDK1 MED13

9.41e-0618617670b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A PITPNM2 ARPP21 HIVEP2 STK32C PAK6 LIME1

9.41e-0618617677278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellEndothelial-B|World / lung cells shred on cell class, cell subclass, sample id

MYCN PARD6G GJC2 GGT5 RADIL KANK3 GPRC5B

1.01e-0518817675959a88728812a5f4cbfa54eddc7a73ccbaa2f68
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 IRX1 PAK6 YBX2 SCNN1A ETNK1 WNK4

1.12e-051911767297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 IRX1 PAK6 YBX2 SCNN1A ETNK1 WNK4

1.12e-051911767e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX1 PAK6 PMEPA1 SCNN1A ETNK1 MTCL1 WNK4

1.16e-051921767e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX1 PAK6 PMEPA1 SCNN1A ETNK1 MTCL1 WNK4

1.16e-05192176761c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A ARPP21 HIVEP2 SRCIN1 STK32C PAK6 CELSR2

1.20e-051931767be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A ARPP21 HIVEP2 SRCIN1 STK32C PAK6 CELSR2

1.20e-0519317670c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A ARPP21 HIVEP2 SRCIN1 STK32C PAK6 CELSR2

1.20e-0519317678689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D SIPA1L3 DNAAF9 PPM1H MAST4 SCNN1A SDK1

1.28e-0519517676477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

PDE4D BCAS3 TBC1D5 SIPA1L3 GLCCI1 COG5 SDK1

1.32e-051961767ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCelldistal-3-Endothelial-Lymphatic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYCN PARD6G GJC2 GGT5 RADIL KANK3 GPRC5B

1.37e-0519717679ea0e2ed9c3f97591a06e70570640996580417d5
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNK1 IRX5 IRX1 PMEPA1 MAST4 CELSR2 TRMT61A

1.37e-051971767b1c6a15bf6c0645952a7247182dc71baf4736869
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TNK1 IRX5 GGT6 KLRG2 HES2 LIME1 CELSR2

1.46e-051991767fe22833e69928a1478df265e1c356c463611dedd
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

RNF44 SIPA1L3 TBC1D10B GTF2F1 TRIM28 TSC22D4 DMWD

1.51e-052001767ad2a6da0b1ae7a9212a3c91e5eec4baa7481d8dc
ToppCellTCGA-Bile_Duct-Primary_Tumor|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

RNF44 SIPA1L3 TBC1D10B GTF2F1 TRIM28 TSC22D4 DMWD

1.51e-0520017670350e5ffd36033099b7e32a1fdd790fff99790dc
ToppCellLPS_only-Myeloid-Dendritic_cells-pDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYCN BLNK CBFA2T3 PMEPA1 SRPK3 SIGLEC1

1.63e-0513517660afe232aa1a1e6c37a5b3183b67d7fa07e0ea791
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TNK1 IRX1 PAK6 REPIN1 REXO1 SCAP

3.81e-0515717664766f7d545bf2d775390589460677519cb92f4d5
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

PITPNM2 PDE4D CAMSAP3 GLCCI1 SCNN1A NR0B2

3.81e-05157176631d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAIN2 NLRP12 TBC1D5 GLCCI1 ZNF516 FAM53B

4.70e-0516317667a04192710f55acf5a4681d5f09942358fdb02ff
ToppCelldroplet-Lung-nan-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM NLRP12 GGT5 AMER2 LMNB1 SCNN1A

4.86e-0516417660e424a69999eee13d27c4ff4f4ba3df64d3c2bda
ToppCelldroplet-Lung-nan-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM NLRP12 GGT5 AMER2 LMNB1 SCNN1A

4.86e-051641766fe9ecdd7a6cbaf910f42654eba75f79bea740a00
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM NLRP12 FOSB AMER2 LMNB1 SCNN1A

5.03e-05165176684eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM NLRP12 FOSB AMER2 LMNB1 SCNN1A

5.03e-051651766af59a095ecc6758abc13d763c00e44447c488167
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MYCN IRX5 RADIL SCNN1A TMEM108 MTCL1

5.03e-051651766b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A FOSB KIF12 PAK6 CELSR2 WNK4

5.38e-051671766b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCelldroplet-Lung-18m-Hematologic-myeloid-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MGAM NLRP12 GGT5 AMER2 LMNB1 SCNN1A

5.56e-051681766937332580a522826b820e0b09080013f19f58479
ToppCelldroplet-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MGAM NLRP12 GGT5 AMER2 LMNB1 SCNN1A

5.56e-051681766b0376e3687fa85f091654196403eecedc219d0cd
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

MYCN SGIP1 PARD6G GJC2 KANK3 GPRC5B

5.56e-0516817664977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF223 FOSB HES2 SCNN1A ATOH1 WNK4

6.13e-05171176648125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

KIF26A PARD6G GJC2 RADIL KANK3 GPRC5B

6.13e-05171176607ff7059071da83da1d8f266a586573920d75b58
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A KIF12 NUTM2G CADPS NR0B2 WNK4

6.54e-05173176646ed379571385684145b5cb6dd4ae340ac546e64
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 HIVEP2 BLNK SCAP RPTOR FAM53B

6.75e-051741766268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ARPP21 BLNK GJC2 CBFA2T3 PMEPA1 MTCL1

6.75e-051741766ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARPP21 BLNK GJC2 CBFA2T3 PMEPA1 MTCL1

6.75e-051741766d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 HIVEP2 BLNK SCAP RPTOR FAM53B

6.75e-0517417664cdf2eedc28d88d18241ee390092426fdf849e79
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARPP21 BLNK GJC2 CBFA2T3 PMEPA1 MTCL1

6.75e-0517417662453419842fd22d066631615403393bfe4449bb8
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARPP21 BLNK GJC2 CBFA2T3 PMEPA1 MTCL1

6.97e-0517517666d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARPP21 BLNK GJC2 CBFA2T3 PMEPA1 MTCL1

6.97e-0517517666839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARPP21 BLNK GJC2 CBFA2T3 PMEPA1 MTCL1

6.97e-0517517669d6135e183179968555670abec39dff9da2c3219
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 BLNK GJC2 RPTOR FAM53B TMEM108

7.19e-05176176629cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 BLNK GJC2 RPTOR FAM53B TMEM108

7.19e-05176176601774a86d7d92f31a056b753f9844f923038003e
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5|TCGA-Lung / Sample_Type by Project: Shred V9

CRYBG2 PARD6G HES2 MICALL1 CELSR2 HR

7.42e-051771766a0c7d08469c513cecf87777c19876884f1511570
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

DGCR2 ARPP21 MAPT DNAAF9 CRY2 AMER2

7.42e-051771766e8ab340b20cd41554c3841fe980e078e878af35f
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITPNM2 MAPT CBFA2T3 INKA2 AATK KANK3

7.66e-0517817666bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A PMEPA1 LPIN3 GAS2L1 MAST4 ZFTA

7.90e-051791766025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A HCN4 VENTX RBMXL2 CADPS WNK4

8.14e-051801766d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD6G GAREM2 SSH3 ZNF516 TMEM108 MEX3B

8.39e-0518117664e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD6G GAREM2 SSH3 ZNF516 TMEM108 MEX3B

8.39e-051811766ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD6G GAREM2 SSH3 ZNF516 TMEM108 MEX3B

8.39e-0518117663a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CRYBG2 NYAP2 CBFA2T3 CADPS SCNN1A NR0B2

8.65e-051821766dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF26B TNS2 GAS2L1 PKD1 ZFTA MED13

8.92e-0518317663ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX1 SCNN1A ETNK1 MTCL1 NR0B2 WNK4

8.92e-05183176603c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYCN PARD6G GJC2 GGT5 RADIL KANK3

9.19e-05184176615cbddea9efb2346a2028d77edfe9ba32923568f
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYCN PARD6G GJC2 GGT5 RADIL KANK3

9.19e-0518417660087c605c161fd8a39aa394f51994a04e8353bf1
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

HIVEP2 SIPA1L3 MAST4 CDK13 ZNF358 PRRC2A

9.19e-051841766e6bf826be31e1723e24c366fc5a1cee9b15589bc
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYCN PARD6G GJC2 GGT5 RADIL KANK3

9.19e-051841766968afa6b5ba84169377a24c150bb68749fa674d9
ToppCell3'-Broncho-tracheal-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYCN PARD6G GJC2 GGT5 RADIL KANK3

9.19e-051841766920f95625978132c2b6c76654ef6298244103e2d
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYCN PARD6G GJC2 RADIL KANK3 GPRC5B

9.47e-051851766f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX1 PAK6 YBX2 SCNN1A ETNK1 WNK4

9.47e-051851766af86e75096c1812ae27a78405355957ee8043d84
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

PRR36 KIF26B PARD6G ZNF750 SCNN1A GPRC5B

9.47e-051851766c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D KIF26B SIPA1L3 MAST4 MTCL1 SDK1

9.75e-051861766b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYCN TNK1 IRX5 CAMSAP3 KIF12 IRX1

1.00e-041871766baff4edc1bf64e3e03864a434fa47075ff7372fd
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-pDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MEF2B BLNK CBFA2T3 PMEPA1 LIME1 SRPK3

1.00e-041871766bf64a6ef5062ec9a0f7095e8c97ce66bfc3bf179
ToppCellwk_20-22-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PARD6G NUTM2G RADIL KANK3 GPRC5B HR

1.00e-04187176655aad84b992412e487a32f4970620189a7380ba6
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SIPA1L3 ASTL CBFA2T3 PPM1H ZNF516 SDK1

1.03e-041881766d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26B KLRG2 PMEPA1 YBX2 SCNN1A GPRC5B

1.03e-041881766315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX1 PAK6 YBX2 SCNN1A ETNK1 WNK4

1.03e-04188176614e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IRX5 PRR36 BLNK IRX1 SCNN1A NR0B2

1.03e-0418817663cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 SGIP1 CBFA2T3 ETNK1 TMEM108 WNK4

1.06e-0418917668e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

CRYBG2 PARD6G HES2 MICALL1 ZNF750 MAST4

1.06e-041891766533c302df467d13ab639232daf4f8cafb808260b
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX1 PAK6 YBX2 SCNN1A ETNK1 WNK4

1.06e-041891766443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

TLK2 ARPP21 CBFA2T3 DNAAF2 AMER2 TSC22D4

1.06e-0418917663717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 SGIP1 CBFA2T3 ETNK1 TMEM108 WNK4

1.06e-041891766fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SGIP1 PARD6G GGT5 RADIL KANK3 GPRC5B

1.10e-0419017668d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 SGIP1 PARD6G CBFA2T3 TMEM108 WNK4

1.10e-0419017667068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX1 PAK6 PMEPA1 SCNN1A ETNK1 WNK4

1.10e-041901766c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX1 PAK6 PMEPA1 SCNN1A ETNK1 WNK4

1.10e-0419017665cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MGAM PDE4D BCAS3 SIPA1L3 BLNK SDK1

1.13e-0419117663e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLNK GLCCI1 MAST4 SRPK3 IRS2 MED13

1.16e-0419217662de242d81dc085ae734eb7d1f091af9a542e0866
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLNK GLCCI1 MAST4 SRPK3 IRS2 MED13

1.16e-041921766ba2a683472a8b785dbf666dc6e94356d879486c3
DrugAcetazolamide [59-66-5]; Down 200; 18uM; PC3; HT_HG-U133A

HIVEP2 BCAS3 INPP5E GMIP RIN1 LMNB1 SSH3 PNRC1 FAM53B IRS2 TSC22D4 ELL

4.24e-08199173121808_DN
Drugbeta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; MCF7; HT_HG-U133A

SIPA1L3 TNS2 CPT2 ARID1A EML3 RIN1 MAST4 ZNF516 MARK4 PNRC1 KDM6A

3.78e-07199173112819_DN
DrugMethapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A

TNK1 MAPT MED1 EML3 GTF2F1 MAST4 LMNB1 SSH1 MARK4 EIF4G1

2.12e-06191173106644_DN
DrugSertaconazole nitrate [99592-39-9]; Down 200; 8uM; MCF7; HT_HG-U133A

TNK1 DGCR2 SIPA1L3 GMIP MED1 EML3 ARAF MAST4 ZNF516 MARK4

2.44e-06194173106811_DN
DrugHydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A

DGCR2 INPP5E SIPA1L3 AGBL5 ZC3H3 RGS12 MICALL1 MAST4 SSH3 MARK4

2.68e-06196173102889_DN
DrugFlecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A

DGCR2 HIVEP2 PRR36 ZC3H3 LMNB1 ZNF358 MARK4 FAM53B IRS2 ELL

2.93e-06198173103843_DN
DrugFurosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A

DGCR2 HIVEP2 NEK9 EML3 MAST4 MARK4 IRS2 TSC22D4 HR

1.76e-0519317393197_DN
Drug5140203; Down 200; 15uM; MCF7; HT_HG-U133A_EA

TNK1 DGCR2 PRR36 EFCAB2 EML3 TBC1D10B SSH1 SSH3 MARK4

1.91e-051951739908_DN
DrugLY294002; Down 200; 10uM; PC3; HT_HG-U133A

MAPT GJC2 MLLT10 PAK6 CRY2 MARK4 EIF4G1 TRMT61A ATPAF2

1.99e-0519617395942_DN
DrugAcacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A

SHANK1 TNS2 MLLT10 INKA2 SCNN1A IRS2 PRRC2A ATPAF2 HR

1.99e-0519617393849_UP
DrugMethantheline bromide [53-46-3]; Down 200; 9.6uM; PC3; HT_HG-U133A

GMIP MLLT10 HES2 RIN1 CELSR2 SSH3 ZNF358 FAM53B TSC22D4

2.07e-0519717395780_DN
DrugCyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

DGCR2 CRYBG2 SIPA1L3 TNS2 RGS12 MAST4 CDK13 TSC22D4 ELL

2.15e-0519817393882_DN
DrugEthaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A

MAPT DVL2 EML3 RGS12 INKA2 MAST4 SSH1 MARK4 HR

2.24e-0519917395337_UP
DrugPiperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A

DGCR2 ARID1A HES2 RIN1 MAST4 CDK13 ZNF358 MARK4 ATPAF2

2.24e-0519917393845_DN
DrugLynestrenol [52-76-6]; Down 200; 14uM; PC3; HG-U133A

TNK1 DGCR2 SIPA1L3 ARID1A HES2 TBC1D10B PNRC1 FAM53B DYRK2

2.33e-0520017391953_DN
Drugselenolanthionine

GGT5 SIGLEC1

5.74e-0521732CID000193608
DrugMethamphetamine

FOXE1 EVC2 PDE4D HCN4 MAPT PARD6G TNS2 PPP6R1 MLLT10 AGBL5 ARID1A PMEPA1 ZNF414 REXO1 MICALL1 DNAAF2 LIME1 TH KANK3 RNF225 SRPK3 DMWD KDM6A SPTY2D1 HR

6.00e-05140117325ctd:D008694
DrugICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A

DGCR2 MAPT TBC1D5 EFCAB2 CBFA2T3 LMNB1 ZNF516 IRS2

7.87e-0518217381663_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

DVL2 BLNK ARID1A ZNF750 CDK13 PNRC1 IRS2 KDM6A

8.82e-0518517381022_UP
DrugPyrantel tartrate [33401-94-4]; Down 200; 11.2uM; HL60; HG-U133A

TRIOBP PPP6R1 ARID1A REPIN1 EML3 TRIM28 MARK4 PRRC2A

1.14e-0419217381413_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

IRX5 INPP5E SIPA1L3 TRIOBP EML3 DNAAF2 GAS2L1 PRRC2A

1.14e-0419217386986_DN
DrugMuramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A

CACNA1A DGCR2 TBC1D10B SCAP MARK4 DMWD PRRC2A ELL

1.18e-0419317383262_UP
DrugMexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A

CACNA1A DGCR2 PRR36 RGS12 MICALL1 TH MAST4 ATPAF2

1.18e-0419317383973_DN
DrugDapsone [80-08-0]; Down 200; 16.2uM; PC3; HT_HG-U133A

CRYBG2 GMIP RIN1 SSH1 MARK4 FAM53B TSC22D4 ELL

1.27e-0419517381827_DN
DrugHomosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A

SIPA1L3 RIN1 MAST4 SSH3 ZNF358 MARK4 FAM53B IRS2

1.27e-0419517384533_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

MAPT EFCAB2 ARID1A ZC3H3 EML3 DMWD GPRC5B TRMT61A

1.27e-0419517386927_DN
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A

TNK1 PRR36 MAPT EML3 CRY2 FAM53B KLHDC4 TRMT61A

1.27e-0419517381700_DN
DrugAntimycin A [1397-94-0]; Down 200; 7.2uM; PC3; HT_HG-U133A

TNK1 BCAS3 TBC1D5 MLLT10 HES2 PMEPA1 MAST4 MARK4

1.27e-0419517385053_DN
DrugRisperidone [106266-06-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A

DVL2 NEK9 ZNF750 MAST4 SSH3 MARK4 TSC22D4 HR

1.27e-0419517383508_DN
DrugSulfacetamide sodic hydrate [6209-17-2]; Down 200; 15.8uM; HL60; HT_HG-U133A

TBC1D5 SIPA1L3 EML3 RIN1 FAM53B ELL TRMT61A DYRK2

1.27e-0419517381859_DN
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; MCF7; HT_HG-U133A

PRR36 EML3 YBX2 GTF2F1 MAST4 FAM53B IRS2 GPRC5B

1.27e-0419517385283_UP
DrugBenzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; MCF7; HT_HG-U133A

TBC1D5 RGS12 RIN1 CDK13 ZNF516 SRPK3 ATPAF2 HR

1.27e-0419517387359_UP
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Down 200; 16.2uM; PC3; HT_HG-U133A

MAPT EML3 CRY2 AATK CELSR2 SSH3 TSC22D4 DYRK2

1.27e-0419517384495_DN
Drugmonastrol; Up 200; 100uM; MCF7; HG-U133A

DGCR2 SIPA1L3 PMEPA1 EML3 RETREG3 RMDN1 SSH3 TRMT61A

1.32e-041961738627_UP
DrugAllantoin [97-59-6]; Down 200; 25.2uM; MCF7; HT_HG-U133A

MAPT EFCAB2 TNS2 EML3 MAST4 SSH3 IRS2 GPRC5B

1.32e-0419617381678_DN
DrugPralidoxime chloride [51-15-0]; Down 200; 23.2uM; HL60; HT_HG-U133A

FOSB DVL2 EML3 SSH3 MARK4 FAM53B DMWD TRMT61A

1.32e-0419617383066_DN
DrugEpivincamine [6835-99-0]; Down 200; 11.2uM; PC3; HT_HG-U133A

MAPT TBC1D5 DVL2 NEK9 CRY2 TH LMNB1 ZNF358

1.32e-0419617384500_DN
DrugDoxepin hydrochloride [1229-29-4]; Up 200; 12.6uM; HL60; HT_HG-U133A

TNK1 DGCR2 PDE4D MAPT GAS2L1 SSH3 ZNF358 TSC22D4

1.36e-0419717382384_UP
Drug(-)-Eseroline fumarate salt [104015-29-4]; Up 200; 12uM; PC3; HT_HG-U133A

PDE4D PAK6 ARID1A HES2 ZC3H3 MARK4 IRS2 ELL

1.36e-0419717387267_UP
DrugSpiramycin [8025-81-8]; Down 200; 4.8uM; HL60; HT_HG-U133A

INPP5E SIPA1L3 EFCAB2 DNAAF2 CDK13 SSH3 TSC22D4 PRRC2A

1.36e-0419717382558_DN
DrugPyrithyldione [77-04-3]; Up 200; 24uM; PC3; HT_HG-U133A

MAPT TRIOBP HES2 TH MAST4 SSH3 ELL DYRK2

1.36e-0419717387153_UP
DrugDapsone [80-08-0]; Down 200; 16.2uM; MCF7; HT_HG-U133A

TNK1 DGCR2 MAPT CRY2 RIN1 MAST4 SSH3 FAM53B

1.36e-0419717381705_DN
DrugAmoxicillin [26787-78-0]; Up 200; 11uM; MCF7; HT_HG-U133A

DGCR2 CRYBG2 KIF26B PAK6 MAST4 SCNN1A ELL HR

1.36e-0419717382620_UP
Drugalpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A

DGCR2 PRR36 MAPT TBC1D5 TRIOBP EML3 IRS2 TRMT61A

1.36e-0419717381635_DN
DrugLysergol [602-85-7]; Down 200; 15.8uM; MCF7; HT_HG-U133A

INPP5E TBC1D5 DVL2 NEK9 EML3 RGS12 CRY2 TRMT61A

1.41e-0419817383261_DN
DrugTremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A

GMIP NEK9 RGS12 CRY2 SSH3 MARK4 TSC22D4 HR

1.41e-0419817383196_DN
DrugOrphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A

DGCR2 CRYBG2 PRR36 MLLT10 NEK9 EML3 MAST4 CDK13

1.41e-0419817383883_DN
DrugChlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A

HIVEP2 DVL2 NEK9 MICALL1 TH MAST4 CDK13 DYRK2

1.41e-0419817383869_DN
DrugErgocryptine-alpha [511-09-1]; Down 200; 7uM; MCF7; HT_HG-U133A

TNK1 DGCR2 SIPA1L3 GMIP REPIN1 EML3 FAM53B GPRC5B

1.41e-0419817383434_DN
DrugSulfamethoxazole [723-46-6]; Down 200; 15.8uM; PC3; HT_HG-U133A

DGCR2 MYBBP1A MLLT10 RIN1 MAST4 TSC22D4 DMWD TRMT61A

1.41e-0419817387366_DN
DrugPropranolol hydrochloride [318-98-9]; Down 200; 13.6uM; MCF7; HT_HG-U133A

MLLT10 ARID1A NEK9 INKA2 GAS2L1 CDK13 MARK4 ATPAF2

1.41e-0419817383396_DN
Drugvinblastine sulfate; Down 200; 0.1uM; PC3; HT_HG-U133A

CRYBG2 HIVEP2 DVL2 TRIOBP GMIP RIN1 MARK4 KDM6A

1.41e-0419817387556_DN
DrugTropine [120-29-6]; Down 200; 28.4uM; MCF7; HT_HG-U133A

MLLT10 CPT2 ZC3H3 MICALL1 DMWD KDM6A TRMT61A ATPAF2

1.41e-0419817386264_DN
DrugHexestrol [84-16-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A

INPP5E EFCAB2 MLLT10 AGBL5 EML3 MICALL1 LMNB1 ATPAF2

1.41e-0419817386252_DN
DrugAcemetacin [53164-05-9]; Down 200; 9.6uM; PC3; HT_HG-U133A

TNK1 DGCR2 MYBBP1A MAPT ARID1A RIN1 ZNF358 ATPAF2

1.46e-0419917386361_DN
DrugPHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A

CRYBG2 MLLT10 ARID1A RGS12 CDK13 MARK4 IRS2 ELL

1.51e-0420017383907_DN
DrugBenzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; HL60; HT_HG-U133A

INPP5E ZC3H3 EML3 PPM1H CRY2 MARK4 TSC22D4 TRMT61A

1.51e-0420017382939_DN
DrugN6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt; Up 200; 20uM; MCF7; HG-U133A

MAPT TBC1D5 ARID1A LMNB1 SSH3 ETNK1 PRRC2A DYRK2

1.51e-042001738591_UP
Diseasecortical thickness

PITPNM2 NYAP2 MAPT INPP5E TBC1D5 TRIOBP DNAAF9 MLLT10 MBD6 KIAA1614 MICALL1 ZNF469 MAST4 CADPS PKD1 FAM53B TMEM108 MTCL1 ATOH1 ELL FOXL1

1.58e-06111316821EFO_0004840
Diseasecortical surface area measurement

CACNA1A PITPNM2 NYAP2 MAPT KIF26B INPP5E TBC1D5 TRIOBP PERM1 DNAAF9 AGBL5 MBD6 PMEPA1 KIAA1614 ZNF469 MAST4 CADPS RMDN1 PKD1 MTCL1 PRRC2A FOXL1 TRMT61A

2.54e-06134516823EFO_0010736
Diseaseserum gamma-glutamyl transferase measurement

NYAP2 ARPP21 SGIP1 SIPA1L3 TRIOBP KLF15 PERM1 ARID1A PMEPA1 CELSR2 SSH1 PKD1 FAM53B SIGLEC1 PRRC2A MED13

7.22e-0591416816EFO_0004532
Diseaseallograft inflammatory factor 1 measurement

NLRP12 PRRC2A

9.63e-0531682EFO_0020135
DiseaseMedulloblastoma

MYCN IRS2 ATOH1 KDM6A

1.90e-04501684C0025149
DiseaseColorectal Carcinoma

SHANK1 EVC2 RBP3 STK32C PAK6 CBFA2T3 ARID1A AMER2 MYLK3 TRIM28 EIF4G1 KDM6A HR

2.04e-0470216813C0009402
Diseaseneurotic disorder

PDE4D ARPP21 MAPT PMEPA1 AATK

2.87e-041011685EFO_0004257
Diseasedaytime rest measurement

CACNA1A HIVEP2 MAPT KIF26B AATK CADPS TMEM108 COG5

3.04e-042951688EFO_0007828
Diseaseregulator of microtubule dynamics protein 1 measurement

NLRP12 RMDN1

3.19e-0451682EFO_0801998
Diseaselifestyle measurement

HIVEP2 SGIP1 MLLT10 GLCCI1 RGS12 CADPS PRRC2A

4.15e-042351687EFO_0010724
Diseaseneuroimaging measurement

MAPT KIF26B TBC1D5 MLLT10 PAK6 MBD6 PMEPA1 GLCCI1 RETREG3 ZNF469 AMER2 MAST4 CADPS PKD1 FAM53B FOXL1

4.22e-04106916816EFO_0004346
Diseasefactor VIII measurement, coronary artery disease

PMEPA1 CELSR2 GPR149 PRRC2A ELL

4.82e-041131685EFO_0001645, EFO_0004630
Diseasebrain connectivity measurement

MAPT KIF26B TBC1D5 TRIOBP MLLT10 KIAA1614 SSH1 FAM53B FOXL1

5.03e-044001689EFO_0005210
Diseasefactor XI measurement, coronary artery disease

BCAS3 PMEPA1 CELSR2 GPR149 ELL

5.22e-041151685EFO_0001645, EFO_0004694
Diseasetriglycerides in small LDL measurement

NYAP2 ARID1A CELSR2 KANK3

5.24e-04651684EFO_0022323
Diseasebrain volume measurement

CACNA1A NYAP2 MAPT TRIOBP MSI1 MLLT10 ZNF469 MAST4 CADPS FAM53B FOXL1

6.39e-0459516811EFO_0006930
Diseasewellbeing measurement

CACNA1A SLAIN2 NYAP2 HIVEP2 SIPA1L3 STIMATE MUC19 PMEPA1 AATK FAM53B SDK1 TRMT61A

6.40e-0469216812EFO_0007869
Diseaseobsessive-compulsive symptom measurement

MGAM MEF2B CADPS

7.25e-04311683EFO_0007802
Diseasemacula measurement

PITPNM2 BCAS3 RBP3 GLCCI1 COG5 MEX3B

7.72e-041891686EFO_0008375
Diseaseneutrophil percentage of leukocytes

NYAP2 MAPT GMIP ARID1A GLCCI1 SCML4 AATK CDK13 ZNF516 MARK4 FAM53B

7.83e-0461016811EFO_0007990
Diseasehair colour measurement

FOXE1 PDE4D NYAP2 KLF15 CBFA2T3 ARID1A ZNF750 ZNF469 ZNF358 KLHDC4 ELL

8.37e-0461516811EFO_0007822
Diseaseswitch-associated protein 70 measurement

FOXE1 NLRP12

8.82e-0481682EFO_0802107
Diseasepseudohypoaldosteronism (is_implicated_in)

SCNN1A WNK4

8.82e-0481682DOID:4479 (is_implicated_in)
Diseaseintellectual disability (implicated_via_orthology)

MEF2B HIVEP2 BOD1L2 IRS2

9.00e-04751684DOID:1059 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

PDPK2P ARID1A SSH1 SSH3 KDM6A HR

9.08e-041951686DOID:1574 (implicated_via_orthology)
Diseasesusceptibility to strep throat measurement

KLRG2 CDK13 MPLKIP ATPAF2

9.46e-04761684EFO_0008408
DiseaseLung diseases

IRX5 IRX1 DNAAF2 SCNN1A

1.04e-03781684C0024115
DiseaseNephroblastoma

MYCN ARID1A TRIM28

1.13e-03361683C0027708
Diseaseamnestic disorder (implicated_via_orthology)

MAPT IRS2

1.13e-0391682DOID:10914 (implicated_via_orthology)
Diseasetotal blood protein measurement

MEF2B NYAP2 INPP5E CBFA2T3 PMEPA1 RGS12 MARK4 PKD1 SIGLEC1

1.14e-034491689EFO_0004536
DiseaseCognition Disorders

MAPT FOSB NR0B2

1.32e-03381683C0009241
Diseasecoronary artery disease

NYAP2 HIVEP2 HCN4 BCAS3 IRX1 PMEPA1 NEK9 SCML4 MAST4 CELSR2 RPTOR GPR149 MARK4 COG5 ELL FOXL1

1.36e-03119416816EFO_0001645
DiseasePseudohypoaldosteronism, Type I

SCNN1A WNK4

1.41e-03101682C0268436
DiseasePseudohypoaldosteronism

SCNN1A WNK4

1.41e-03101682C0033805
DiseaseHyperpotassemia and Hypertension, Familial

SCNN1A WNK4

1.41e-03101682C2713447
DiseasePseudohypoaldosteronism, Type I, Autosomal Recessive

SCNN1A WNK4

1.41e-03101682C1449843
DiseasePseudohypoaldosteronism, Type II

SCNN1A WNK4

1.41e-03101682C1449844
DiseasePseudohypoaldosteronism, Type I, Autosomal Dominant

SCNN1A WNK4

1.41e-03101682C1449842
Diseaseneurodegenerative disease (implicated_via_orthology)

MAPT DVL2 YBX2 MARK4 SCNN1A

1.48e-031451685DOID:1289 (implicated_via_orthology)
Diseaselymphocyte percentage of leukocytes

NYAP2 GMIP CBFA2T3 ARID1A GLCCI1 SCML4 AATK CDK13 MARK4 FAM53B ELL

1.56e-0366516811EFO_0007993
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

SHANK1 NLRP12 MLLT10 ARID1A KDM6A

1.62e-031481685C0279702
Diseasehippocampal CA4 volume

GMIP MAST4 FAM53B

1.65e-03411683EFO_0009396
Diseaselate onset Parkinson's disease (is_implicated_in)

MAPT EIF4G1

1.71e-03111682DOID:0060892 (is_implicated_in)
Diseaselignoceroylcarnitine (C24) measurement

CPT2 RMDN1

1.71e-03111682EFO_0800541
Diseasecreatinine measurement

NYAP2 KIF26B BCAS3 SIPA1L3 MED1 ARID1A PMEPA1 KIAA1614 RGS12 TH TBC1D10B CELSR2 FAM53B ELL

1.73e-0399516814EFO_0004518
Diseaseosteoarthritis

PITPNM2 MAPT KIF26B KIF12 PARD6G COG5

1.76e-032221686MONDO_0005178
Diseaseage at menopause

PITPNM2 MGAM NYAP2 SGIP1 RNF44 MYLK3 PRRC2A

1.79e-033021687EFO_0004704
Diseaseobsolete_red blood cell distribution width

NYAP2 BCAS3 INPP5E TBC1D5 IRX1 CBFA2T3 REXO1 PPM1H MAST4 GAREM2 ZNF516 MARK4 IRS2 TSC22D4 NUTM2F COG5 ELL

1.82e-03134716817EFO_0005192
Diseasebasophil count

TRIOBP GMIP ZNF414 GLCCI1 GGT5 ZNF469 MARK4 FAM53B MEX3B

1.87e-034831689EFO_0005090
DiseaseChildhood Medulloblastoma

MYCN IRS2 ATOH1

1.89e-03431683C0278510
DiseaseMelanotic medulloblastoma

MYCN IRS2 ATOH1

1.89e-03431683C1275668
DiseaseMedullomyoblastoma

MYCN IRS2 ATOH1

1.89e-03431683C0205833
DiseaseDesmoplastic Medulloblastoma

MYCN IRS2 ATOH1

1.89e-03431683C0751291
DiseaseAdult Medulloblastoma

MYCN IRS2 ATOH1

1.89e-03431683C0278876
Diseaseworry measurement

ARPP21 MAPT STIMATE PMEPA1 RGS12

1.93e-031541685EFO_0009589
Diseasebody fat percentage

NYAP2 MLLT10 ZC3H3 PMEPA1 EML3 LMNB1 RPTOR PRRC2A HR

2.01e-034881689EFO_0007800
Diseasealcohol consumption measurement

CACNA1A MGAM NYAP2 SGIP1 KIF26A MAPT MED1 RGS12 MICALL1 MAST4 CADPS RPTOR ZNF516 EIF4G1 SDK1 GPRC5B

2.02e-03124216816EFO_0007878
Diseasemultisite chronic pain

MLLT10 PMEPA1 INKA2 SDK1

2.16e-03951684EFO_0010100
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

NYAP2 ARPP21 SGIP1 KIF26A MAPT TBC1D5 STIMATE BLNK STK32C AATK SDK1 ELL

2.21e-0380116812EFO_0003888, EFO_0007052, MONDO_0002491
Diseasedyslexia

PDE4D MAPT TBC1D5 LMNB1 COG5

2.40e-031621685EFO_0005424
DiseaseConnective Tissue Diseases

ZNF469 PKD1

2.41e-03131682C0009782
DiseaseNeuroblastoma

MYCN ARID1A TH

2.45e-03471683C0027819
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

GMIP ARID1A CELSR2 SPTY2D1

2.51e-03991684EFO_0004611, EFO_0007878
DiseaseLiver carcinoma

MAPT FOSB MED1 ARID1A TH SCAP TONSL IRS2 NR0B2

2.59e-035071689C2239176
Diseasethyroid stimulating hormone measurement

PDE4D NYAP2 BCAS3 PPP6R1 MARK4 SDK1 FCAMR

2.60e-033231687EFO_0004748
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

GMIP ARID1A CELSR2 SPTY2D1

2.79e-031021684EFO_0004329, EFO_0004611
DiseaseDyskinesia, Medication-Induced

FOSB TH

3.22e-03151682C0751088
DiseaseDyskinesia, Drug-Induced

FOSB TH

3.22e-03151682C0013386
Diseasemonocyte percentage of leukocytes

NLRP12 CRYBG2 NYAP2 INPP5E ARID1A GLCCI1 GGT5 ZNF516 MARK4 FAM53B COG5

3.24e-0373116811EFO_0007989
Diseaseplatelet crit

NYAP2 KIF26A BCAS3 TBC1D5 RTTN ARID1A PMEPA1 KIAA1614 LPIN3 MAST4 CDK13 MARK4 IRS2

3.25e-0395216813EFO_0007985
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

MYCN MLLT10 KDM6A

3.45e-03531683C1961099
Diseaseapolipoprotein A 1 measurement

PITPNM2 MGAM NYAP2 STIMATE PERM1 ARID1A PMEPA1 CELSR2 GPR149 FAM53B COG5 ELL

3.50e-0384816812EFO_0004614
Diseasefatty acid measurement

MEF2B NYAP2 TRIM31 GMIP PMEPA1 RGS12 CELSR2 KANK3

3.64e-034361688EFO_0005110
DiseaseQT interval

SGIP1 IRX1 YBX2 SCAP CDK13 ZNF358 MPLKIP ATOH1 TSC22D4

3.65e-035341689EFO_0004682
Diseasecoronary artery disease, factor VII measurement

PMEPA1 CELSR2 GPR149 ELL

3.79e-031111684EFO_0001645, EFO_0004619
Diseasetriglycerides in medium VLDL measurement

NYAP2 ARID1A CELSR2

3.83e-03551683EFO_0022155
Diseasevascular endothelial growth factor measurement

EVC2 TMEM108 MTCL1

4.03e-03561683EFO_0004762
Diseasegrip strength measurement

ARPP21 MLLT10 PAK6 CADPS PKD1 ATOH1 PRRC2A

4.04e-033501687EFO_0006941
Diseaseimmature granulocyte count

NLRP12 MARK4

4.14e-03171682EFO_0803542
Diseasesphingomyelin 14:0 measurement

PDE4D PAK6

4.14e-03171682EFO_0010390
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TLK2 MED13

4.14e-03171682DOID:0060307 (is_implicated_in)
DiseaseR-warfarin measurement

HIVEP2 CPT2 PMEPA1 TBX18 TMEM108 MEX3B

4.22e-032651686EFO_0803324
Diseasefree cholesterol to total lipids in medium VLDL percentage

NYAP2 RGS12 CELSR2

4.23e-03571683EFO_0022284
Diseasebreast cancer (is_marker_for)

MAPT BCAS3 PMEPA1 CDK13 KDM6A

4.24e-031851685DOID:1612 (is_marker_for)
Diseasebrain measurement, neuroimaging measurement

KIF26B TBC1D5 TRIOBP MLLT10 MBD6 MAST4 CADPS FAM53B ATOH1

4.42e-035501689EFO_0004346, EFO_0004464
Diseasegranulocyte percentage of myeloid white cells

NLRP12 NYAP2 ARID1A GLCCI1 GGT5 ZNF516

4.46e-032681686EFO_0007997
Diseaselymphocyte measurement

NLRP12 BCAS3 LMNB1 FAM53B

4.56e-031171684EFO_0803546
DiseaseHMG CoA reductase inhibitor use measurement

NYAP2 ARID1A PMEPA1 RGS12 CELSR2

4.63e-031891685EFO_0009932
DiseaseTourette syndrome, schizophrenia

PITPNM2 TBC1D5

4.64e-03181682EFO_0004895, MONDO_0005090
Diseaseinfant grey matter volume measurement

CDK13 MPLKIP

4.64e-03181682EFO_0008368
Diseasecholesterol in medium HDL measurement

NYAP2 ARID1A CELSR2

4.67e-03591683EFO_0021903
Diseasefree cholesterol to total lipids in very large VLDL percentage

NYAP2 RGS12 CELSR2

4.67e-03591683EFO_0022289
Diseasevon Willebrand factor measurement, coronary artery disease

PMEPA1 CELSR2 GPR149 ELL

4.70e-031181684EFO_0001645, EFO_0004629
Diseasetriglycerides to total lipids in large HDL percentage

NYAP2 ARID1A RGS12

4.89e-03601683EFO_0022330
Diseasetotal lipids in VLDL measurement

NYAP2 ARID1A CELSR2

4.89e-03601683EFO_0022314
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

NYAP2 MLLT10 PMEPA1 EML3 RPTOR PRRC2A HR

4.99e-033641687EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasetriglycerides in small VLDL measurement

NYAP2 ARID1A KANK3

5.12e-03611683EFO_0022145
Diseasephospholipids in HDL measurement

NYAP2 ARID1A CELSR2

5.12e-03611683EFO_0022293
Diseaseperipheral neuropathy, response to docetaxel trihydrate

NYAP2 IRX1

5.17e-03191682EFO_0003100, GO_1902519
Diseasehematocrit

SLAIN2 NYAP2 HIVEP2 MAPT BCAS3 STIMATE KLF15 DNAAF9 IRX1 TH MARK4 IRS2 ELL

5.35e-03101116813EFO_0004348

Protein segments in the cluster

PeptideGeneStartEntry
GSRPAGLPGLGSSTQ

AGBL5

671

Q8NDL9
GATGRSPRTPRASGP

CACNA1A

2446

O00555
GERPGVPAGSGLSAS

CAMLG

11

P49069
PPRAAGPGGGSLASS

AMER2

141

Q8N7J2
AASSPPGERGRSASP

ELL

306

P55199
STRASGGGGPINPAS

BOD1L2

16

Q8IYS8
SLGSLPGPGAARGPS

GLCCI1

91

Q86VQ1
RGSSASEGSRGGPPP

CELSR2

2866

Q9HCU4
GGRCSPVPGLSSSPS

BCAS3

476

Q9H6U6
LSSGGPQSPLRGSTG

CAMSAP3

361

Q9P1Y5
PGTTPPAASSSRGGE

DMWD

466

Q09019
SPARSSGNDAPPGGS

CCER1

226

Q8TC90
RSRKSPSPAGGGSSP

CDK13

336

Q14004
PPSRGSTGGAPNLRA

DVL2

646

O14641
LPTGGFSGSGPPISQ

ARPP21

601

Q9UBL0
RSPDPSGSSAGGQPV

ASTL

321

Q6HA08
LASSPRSRPGAGAPG

ASTL

366

Q6HA08
VGPGAPSRPLSAGSG

CPT2

16

P23786
LGGSRASPAPAPSRS

IRX5

371

P78411
SGTGSSDREPPRGAP

MTCL1

236

Q9Y4B5
GPFPTSRARGSPGDT

MTCL1

1531

Q9Y4B5
RSRASPGSPGRPGSG

RADIL

811

Q96JH8
LSSPRGGTPGSGAAA

ARID1A

231

O14497
SSRAGGGRPSSPSPS

CADPS

81

Q9ULU8
PRPAQGSSSPGIQSG

EFCAB2

51

Q5VUJ9
GSSSPGIQSGPSSRP

EFCAB2

56

Q5VUJ9
GIQSGPSSRPGSPRG

EFCAB2

61

Q5VUJ9
PSSRPGSPRGAEQAG

EFCAB2

66

Q5VUJ9
PRGGPSTPSTSVAGG

LPIN3

276

Q9BQK8
GGSSSPRFLPRGNAP

MBD6

196

Q96DN6
APATGQLPGRSSPAG

PAK6

336

Q9NQU5
HPQGSPRTSTPFGSG

MPLKIP

111

Q8TAP9
LNRPAGGPSASMSPG

ATPAF2

16

Q8N5M1
GDSSPGPSASQGPRA

NEK9

26

Q8TD19
SQGSGRRPGDPGSTP

NCKAP5L

646

Q9HCH0
GGRGPARPTVCSPSS

INKA2

81

Q9NTI7
RGSPSSGGNPLSGVA

INPP5E

151

Q9NRR6
ALVGAPSSRPGSGGD

DNAAF2

96

Q9NVR5
SRGPPRAGAPASRTG

GJC2

381

Q5T442
GSLRGRGPSPAAASP

GMIP

906

Q9P107
GRAGDSSGPSAPAPA

HES2

131

Q9Y543
GRSQPPCSEGARSPG

KIF12

626

Q96FN5
GTTHARTTGPPDPGT

MGAM

66

O43451
GSRPTPEGAGSALGS

KIF26B

51

Q2KJY2
SAGPNGERPLSSTGP

KDM6A

651

O15550
LSRASAGAGTGPGSP

KIAA1614

971

Q5VZ46
MGSRAGGPTTPLSPT

LMNB1

11

P20700
SPRTQGRGGPASVPS

DYNC1LI2

391

O43237
GRGGPASVPSSSPGT

DYNC1LI2

396

O43237
PSPRSRSRSGPSGGC

CCDC194

211

A0A1B0GVG4
GPGSGPDSRLSTGLA

HR

541

O43593
SASGPGGRTPAGTPV

FAM53B

341

Q14153
RPSLEGGRSPATGPS

PNRC1

121

Q12796
TRPSPGSPGHFSGGT

MUC19

1866

Q7Z5P9
TTRPSAVGSGKTGPP

MUC19

2856

Q7Z5P9
APGAGQGASSSRPDP

MYLK3

281

Q32MK0
AGRSPLDPMTSPGSG

PDE4D

161

Q08499
GPGSRRGGSPPTAFS

DBX1

86

A6NMT0
RIPPGRSGAGPESST

EVC2

61

Q86UK5
GTPMAASTPRGSSGP

KIF26A

891

Q9ULI4
LGPGTRSGTRPGPFS

MICALL1

221

Q8N3F8
TESSTPPGIPGGSRQ

PDPK2P

6

Q6A1A2
GAAPGGSRSRTPTSP

NYAP2

496

Q9P242
GAPSSPGTAPASRGF

PITPNM2

816

Q9BZ72
ASPSEAGSAGPSRPG

CBFA2T3

626

O75081
PSSSGGSGQLPDRPQ

NR0B2

126

Q15466
PPGSTPSRTGGFLGT

MSI1

296

O43347
PSRTGGFLGTTSPGP

MSI1

301

O43347
RATSSGGPPLTAGPQ

HCN4

1171

Q9Y3Q4
GRRSPGGTSPERSPG

MEF2B

331

Q02080
TPAATGGSQPPSMGR

MYBBP1A

1196

Q9BQG0
RALGSSGPPSDGTAG

PARD6G

261

Q9BYG4
RLGGPCPPSSNSGIS

PMEPA1

201

Q969W9
SGTTSGPGPARPARA

FOSB

126

P53539
NGGTIPTAPPSHTGR

GPRC5B

386

Q9NZH0
APGPSLRRSGGCSPS

GPR149

256

Q86SP6
GPAGPAPTSAAGRTF

IRS2

706

Q9Y4H2
GPGRSTMPTPGNTAA

COG5

311

Q9UP83
SRGGSDGTPRGSPSP

ARAF

246

P10398
RRTPGATRPAAPGTG

FCAMR

236

Q8WWV6
KPVGAAGGSSTPSPR

KLRG2

131

A4D1S0
TPASPPGTASGRNSG

BLNK

216

Q8WV28
AGSMSSAGPRPLPSG

CRY2

541

Q49AN0
GDSGRTANGLPGPRS

GAS2L1

581

Q99501
QGRSTGSLGSVAPPP

GGT6

81

Q6P531
SHLPRPTAGGPRSTG

CRYBG2

251

Q8N1P7
GGSQRPTPPGSCRTR

ATOH1

261

Q92858
LPRARSPGGSSRGSP

DNAAF9

11

Q5TEA3
PRGSGTTPSPVSGDR

GGT5

436

P36269
RTASTPTPPQTGGGL

EIF4G1

201

Q04637
SGSTPAAEALPGGGR

DGCR2

526

P98153
GSFRPDSPGSGNARP

FGA

391

P02671
TAGSGSRGLPPSSPM

MARK4

461

Q96L34
GGAVPPAPRGSSASQ

MAST4

101

O15021
TGDGPGSPLRPASRS

FOXL1

236

Q12952
GVPRSPRGSGRSSPA

KANK3

156

Q6NY19
LSPSGTGPTPRSGCQ

KLHDC4

221

Q8TBB5
SSGRERCSPPPGGAS

KLF15

186

Q9UIH9
GAGGAGPAPATPSRT

EML3

871

Q32P44
PALPRGRPGTEGSTS

ETNK1

51

Q9HBU6
GCGPSPGARTTLGSP

SDIM1

26

Q6ZPB5
TPAGPGARTPLTGFS

SDK1

2196

Q7Z5N4
TLGPRPSPGGSAGAS

SCNN1A

646

P37088
SPLQFRGTPGRGSSP

SCAP

1041

Q12770
GATRSGVGTGPPSPI

DYRK2

36

Q92630
GHSTGSQRPPDSPGA

PERM1

161

Q5SV97
KSPGSAGRSQTPPGV

MED1

1041

Q15648
SSRAPAGSSRGPSPG

PKD1

4251

P98161
ERSPGGGPAAPVSSS

MEX3B

381

Q6ZN04
QSPVPSSGLLSPGGR

NUTM2F

656

A1L443
QSPVPSSGLLSPGGR

NUTM2G

641

Q5VZR2
PRGGNGSGRLSSSPP

GAREM2

491

Q75VX8
GSPGGSSAPPREVTT

RUSC1

356

Q9BVN2
PGSSSPRPSVVGRTG

RTTN

306

Q86VV8
PSGGSSRGNSRPGTP

GTF2F1

376

P35269
ASPGRGSHGQTPSPG

SYN1

426

P17600
TSGDSRPAAGRGPPR

REXO1

461

Q8N1G1
PGSSSAGGRTTSGPP

TRIM31

336

Q9BZY9
GVPGSRGSPATSPHL

RIN1

326

Q13671
AGSLGPGSPVRAGAS

SLAIN2

41

Q9P270
PGSPVRAGASIPSSG

SLAIN2

46

Q9P270
PTSPGPQARSFTGGL

TSC22D4

156

Q9Y3Q8
GRLAGPASPPAGGSS

FOXE1

301

O00358
SPSATGPSGGQPRAL

AATK

921

Q6ZMQ8
EPSSSTPRAPGGAGA

NKX6-3

201

A6NJ46
PGSTRLLSPGAAAGG

IRX1

291

P78414
PGPVSSPGRASGTTR

PRR36

111

Q9H6K5
SPGRASGTTRPGPLG

PRR36

116

Q9H6K5
SNLGGPGSSRTPPTG

PRRC2A

2066

P48634
PGSSRTPPTGRSFSG

PRRC2A

2071

P48634
STPTGLAGGSRDPPR

SIPA1L3

1386

O60292
RTPRTPRGAGGPASA

MED13

1016

Q9UHV7
PGVRQPGSSSSSAPG

SPTY2D1

366

Q68D10
GQPASSSGGPGRPIS

SPTY2D1

436

Q68D10
PKRAAPSGPARSSGG

RBMXL2

161

O75526
APSPSPGSSGGSRGS

TRIOBP

1241

Q9H2D6
LPSGRPGTTGPAGAQ

RPTOR

901

Q8N122
RSEGSAQAAPGPGSP

REPIN1

316

Q9BWE0
RPSSSGTPREGPAGG

SHANK1

516

Q9Y566
SSGRLTPSPRGGPFN

SHANK1

941

Q9Y566
PPAGSRRADTSGPGA

SSH1

716

Q8WYL5
VSRSPPGSGASTPVG

SSH3

6

Q8TE77
ERRGSSAAASPGSPP

STK32C

6

Q86UX6
HPGGARAGPSPASSS

SRPK3

321

Q9UPE1
PASSSPAPGGGRSLS

SRPK3

331

Q9UPE1
PAPGGGRSLSAGSQT

SRPK3

336

Q9UPE1
AGGSAPGTSPGRSVP

TLK2

91

Q86UE8
GRGSSPRGSLSPRSP

MLLT10

676

P55197
AGSPRSPGTPGSERV

RNF223

31

E7ERA6
GVPTTPGPASGSTFR

RETREG3

6

Q86VR2
SPRAGSAATGSPGRP

ZNF750

401

Q32MQ0
PVPAPGGGGFSRSAT

ZNF516

916

Q92618
SGPAAGTPSAPGSRT

YBX2

51

Q9Y2T7
PGSRTPGNPATAVSG

YBX2

61

Q9Y2T7
SPRRPQGGSDAPSGA

ZNF414

296

Q96IQ9
SGSVGGPARPASGPR

ZC3H3

276

Q8IXZ2
GRSQASGGPPTSDLP

RGS12

1411

O14924
PVSRSLGPLGGGSQT

RBP3

281

P10745
HGRGPPTAGSTAQSP

MYCN

136

P04198
TRGGGSSPQRPPSQG

RBMXL3

111

Q8N7X1
HSRAPQGSGPSSPGS

RNF225

11

M0QZC1
QGSGPSSPGSLSAPR

RNF225

16

M0QZC1
SGGRSSGATPVSGPP

SRCIN1

616

Q9C0H9
SLRGGVGAPGSPSTP

PPM1H

211

Q9ULR3
GAAPGSRLPAGTSGS

RMDN1

16

Q96DB5
LASPGGSPKGSPARS

TBX18

111

O95935
GPGPGTTSGASSPAR

SGIP1

431

Q9BQI5
SAQSRLGPGPPRGHS

TONSL

801

Q96HA7
PVGQRRFSAGPGSTP

RNF44

16

Q7L0R7
SRSALRPSTAGPGPG

SYT15B

36

X6R8R1
GPAGSDTSPFRSGTP

TRMT61A

256

Q96FX7
LRASNPGPSGAPGTR

nan

6

A6NN06
PGPSGAPGTRRHFST

nan

11

A6NN06
KSRGSRAAGGAPSPP

TBC1D10B

666

Q4KMP7
SPGSPGTPGSRSRTP

MAPT

516

P10636
STLQGVGGPEGSSPR

SIGLEC1

1026

Q9BZZ2
GNASRGLPGGPPSTV

STIMATE

6

Q86TL2
LRASNPGPSGAPGTR

nan

6

Q5XG85
PGPSGAPGTRRHFST

nan

11

Q5XG85
LGQPPGVRSGGSTDS

PPP6R1

656

Q9UPN7
GPSSQGSGSPRPGTK

ZNF469

3701

Q96JG9
LRASNPGPSGAPGTR

nan

6

Q5VV11
PGPSGAPGTRQHFST

nan

11

Q5VV11
VLSLGPRPTGGGSSP

TNK1

506

Q13470
LRPTAGSGPDTRTPG

TP53TG3

21

Q9ULZ0
GPGPPSVGSARSSVS

WTIP

131

A6NIX2
PGGREFTGSPPSSAT

TBC1D5

546

Q92609
GGSPSPGSPRRKQTG

TMC2

61

Q8TDI7
GSRAPLPGQKSSGPS

HIVEP2

1546

P31629
SIPRSGPGSDFSPGD

WNK4

626

Q96J92
TAGGPRTSPMSSGGP

SCML4

286

Q8N228
RTSPMSSGGPSAPGL

SCML4

291

Q8N228
PGAHSPRAGSISPGS

TNS2

821

Q63HR2
SPGGHSDGASPRSPV

TNS2

991

Q63HR2
SLGSLPGPGQTSGAR

VENTX

41

O95231
GSAPLPSSRARGPAS

ZFTA

61

C9JLR9
PRAPGPLSKQGSGSS

TRIM28

426

Q13263
GLSPGTSSGRNPDPG

ZNF358

451

Q9NW07
TSSGRNPDPGSGPGT

ZNF358

456

Q9NW07
PRPPGSSRKGAGNSS

TMEM108

166

Q6UXF1
VRGQGAPGPSLTGSP

TH

31

P07101
GAGTPPASSCPSLGR

LIME1

271

Q9H400
RDTPPGGPSSLGNQS

NLRP12

96

P59046