Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K9me/H3K9me2 demethylase activity	KDM3B KDM3A	4.94e-05	5	45	2	GO:0140683
GeneOntologyMolecularFunction	lactate transmembrane transporter activity	SLC16A1 SLC16A7	7.41e-05	6	45	2	GO:0015129
GeneOntologyMolecularFunction	histone H3K9 demethylase activity	KDM3B KDM3A	4.44e-04	14	45	2	GO:0032454
GeneOntologyMolecularFunction	beta-1,3-galactosyltransferase activity	B3GALT2 C1GALT1	5.12e-04	15	45	2	GO:0048531
GeneOntologyMolecularFunction	chromatin DNA binding	KDM3B KDM3A HDAC2 DHX9	5.38e-04	167	45	4	GO:0031490
GeneOntologyMolecularFunction	amino acid binding	GRIK1 CAD DDC	5.96e-04	73	45	3	GO:0016597
GeneOntologyMolecularFunction	secondary active monocarboxylate transmembrane transporter activity	SLC16A1 SLC16A7	8.29e-04	19	45	2	GO:0015355
GeneOntologyMolecularFunction	promoter-specific chromatin binding	CHD7 HDAC2 DHX9	8.66e-04	83	45	3	GO:1990841
GeneOntologyMolecularFunction	single-stranded DNA helicase activity	WRNIP1 DHX9	1.22e-03	23	45	2	GO:0017116
GeneOntologyMolecularFunction	dioxygenase activity	KDM3B KDM3A PTGS1	1.40e-03	98	45	3	GO:0051213
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM3B KDM3A	1.81e-03	28	45	2	GO:0141052
GeneOntologyMolecularFunction	histone demethylase activity	KDM3B KDM3A	2.22e-03	31	45	2	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	KDM3B KDM3A	2.36e-03	32	45	2	GO:0140457
GeneOntologyMolecularFunction	galactosyltransferase activity	B3GALT2 C1GALT1	2.82e-03	35	45	2	GO:0008378
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	WRNIP1 CHD7 DHX9	2.93e-03	127	45	3	GO:0008094
GeneOntologyMolecularFunction	3'-5'-RNA exonuclease activity	ERI2 CNOT1	3.15e-03	37	45	2	GO:0000175
GeneOntologyMolecularFunction	RNA exonuclease activity, producing 5'-phosphomonoesters	ERI2 CNOT1	3.67e-03	40	45	2	GO:0016896
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	GRIK1 CHRNB3	4.23e-03	43	45	2	GO:0005231
GeneOntologyMolecularFunction	demethylase activity	KDM3B KDM3A	4.42e-03	44	45	2	GO:0032451
GeneOntologyMolecularFunction	RNA exonuclease activity	ERI2 CNOT1	4.62e-03	45	45	2	GO:0004532
GeneOntologyMolecularFunction	helicase activity	WRNIP1 CHD7 DHX9	5.41e-03	158	45	3	GO:0004386
GeneOntologyBiologicalProcess	response to organic cyclic compound	PLCB1 TXNIP KDM3A CAD SLC16A1 CTSK CNOT1 HDAC2 PENK DHX9	5.61e-05	1048	44	10	GO:0014070
GeneOntologyBiologicalProcess	plasma membrane lactate transport	SLC16A1 SLC16A7	6.64e-05	6	44	2	GO:0035879
GeneOntologyBiologicalProcess	behavior	PLCB1 GRIK1 CHD7 MYO15A OBP2B SLC16A1 PTGS1 HDAC2 PENK	9.12e-05	891	44	9	GO:0007610
GeneOntologyBiologicalProcess	pyruvate transmembrane transport	SLC16A1 SLC16A7	9.28e-05	7	44	2	GO:1901475
GeneOntologyBiologicalProcess	pyruvate transport	SLC16A1 SLC16A7	1.59e-04	9	44	2	GO:0006848
GeneOntologyBiologicalProcess	lactate transport	SLC16A1 SLC16A7	1.59e-04	9	44	2	GO:0015727
GeneOntologyBiologicalProcess	lactate transmembrane transport	SLC16A1 SLC16A7	1.59e-04	9	44	2	GO:0035873
GeneOntologyBiologicalProcess	response to nicotine	CHRNB3 HDAC2 PENK	2.57e-04	58	44	3	GO:0035094
GeneOntologyBiologicalProcess	cellular response to organic cyclic compound	PLCB1 KDM3A SLC16A1 CNOT1 HDAC2 PENK DHX9	2.69e-04	605	44	7	GO:0071407
GeneOntologyBiologicalProcess	sarcomere organization	NEB MYOZ1 HDAC2	2.71e-04	59	44	3	GO:0045214
GeneOntologyCellularComponent	axon terminus	GRIK1 CAD PRSS12 TULP1 PENK	7.70e-05	210	44	5	GO:0043679
GeneOntologyCellularComponent	neuron projection terminus	GRIK1 CAD PRSS12 TULP1 PENK	1.26e-04	233	44	5	GO:0044306
GeneOntologyCellularComponent	presynapse	GRIK1 CAD ATG9A PRSS12 DDC CHRNB3 TULP1 PENK	4.60e-04	886	44	8	GO:0098793
GeneOntologyCellularComponent	histone deacetylase complex	KDM3B KDM3A HDAC2	7.62e-04	85	44	3	GO:0000118
GeneOntologyCellularComponent	terminal bouton	GRIK1 CAD PRSS12	1.08e-03	96	44	3	GO:0043195
Domain	MCT	SLC16A1 SLC16A7	5.65e-05	5	45	2	IPR004743
Domain	JmjC	KDM3B KDM3A	1.51e-03	24	45	2	PF02373
Domain	EGF_3	ADGRE4P MEGF8 TNXB PTGS1	2.43e-03	235	45	4	PS50026
Domain	EGF	ADGRE4P MEGF8 TNXB PTGS1	2.43e-03	235	45	4	SM00181
Domain	JMJC	KDM3B KDM3A	2.69e-03	32	45	2	PS51184
Domain	JmjC_dom	KDM3B KDM3A	2.69e-03	32	45	2	IPR003347
Domain	JmjC	KDM3B KDM3A	2.86e-03	33	45	2	SM00558
Domain	EGF-like_dom	ADGRE4P MEGF8 TNXB PTGS1	2.99e-03	249	45	4	IPR000742
Domain	DNA/RNA_helicase_DEAH_CS	CHD7 DHX9	3.21e-03	35	45	2	IPR002464
Domain	DEAH_ATP_HELICASE	CHD7 DHX9	3.78e-03	38	45	2	PS00690
Domain	CUB	CSMD2 MEGF8	6.21e-03	49	45	2	PF00431
Domain	CUB	CSMD2 MEGF8	6.46e-03	50	45	2	SM00042
Domain	fn3	CNTN4 MERTK TNXB	6.96e-03	162	45	3	PF00041
Domain	-	CSMD2 MEGF8	6.97e-03	52	45	2	2.60.120.290
Domain	CUB	CSMD2 MEGF8	7.23e-03	53	45	2	PS01180
Domain	CUB_dom	CSMD2 MEGF8	8.33e-03	57	45	2	IPR000859
Pathway	REACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT	SLC16A1 SLC16A7	8.93e-05	6	35	2	MM17217
Pathway	REACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT	SLC16A1 SLC16A7	8.93e-05	6	35	2	M27355
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SNRNP27 FAM120B CHD7 CAD SNRPB2 SLC16A1 CNOT1 TNXB HDAC2 DHX9	9.66e-07	1082	45	10	38697112
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	KDM3B PLCB1 CHD7 NEB CSMD2 MEGF8 CNOT1 AASS	1.45e-06	638	45	8	31182584
Pubmed	Monocarboxylate transporter expression in mouse brain.	SLC16A1 SLC16A7	1.64e-06	2	45	2	9725820
Pubmed	Polymorphisms of monocarboxylate transporter genes are associated with clinical outcomes in patients with colorectal cancer.	SLC16A1 SLC16A7	1.64e-06	2	45	2	25492048
Pubmed	Presence and localization of three lactic acid transporters (MCT1, -2, and -4) in separated human granulocytes, lymphocytes, and monocytes.	SLC16A1 SLC16A7	1.64e-06	2	45	2	15505343
Pubmed	Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis.	SLC16A1 SLC16A7	1.64e-06	2	45	2	36814318
Pubmed	Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures.	SLC16A1 SLC16A7	1.64e-06	2	45	2	12836157
Pubmed	Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain.	SLC16A1 SLC16A7	1.64e-06	2	45	2	9520480
Pubmed	Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas.	SLC16A1 SLC16A7	4.91e-06	3	45	2	18188595
Pubmed	Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis.	MERTK TULP1	4.91e-06	3	45	2	20978472
Pubmed	Basigin interacts with both MCT1 and MCT2 in murine spermatozoa.	SLC16A1 SLC16A7	4.91e-06	3	45	2	21792931
Pubmed	Genetic variations in monocarboxylate transporter genes as predictors of clinical outcomes in non-small cell lung cancer.	SLC16A1 SLC16A7	4.91e-06	3	45	2	25578492
Pubmed	Identification of the essential extracellular aspartic acids conserved in human monocarboxylate transporters 1, 2, and 4.	SLC16A1 SLC16A7	4.91e-06	3	45	2	32819565
Pubmed	Enhanced expression of three monocarboxylate transporter isoforms in the brain of obese mice.	SLC16A1 SLC16A7	4.91e-06	3	45	2	17599960
Pubmed	Cellular expression of a sodium-dependent monocarboxylate transporter (Slc5a8) and the MCT family in the mouse kidney.	SLC16A1 SLC16A7	4.91e-06	3	45	2	18751721
Pubmed	Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes.	SLC16A1 SLC16A7	4.91e-06	3	45	2	19876643
Pubmed	Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis.	KDM3B KDM3A	9.81e-06	4	45	2	29526734
Pubmed	Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation.	KDM3B KDM3A	9.81e-06	4	45	2	23593242
Pubmed	Aberrant histone modification in peripheral blood B cells from patients with systemic sclerosis.	KDM3A HDAC2	9.81e-06	4	45	2	23891737
Pubmed	JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.	KDM3B KDM3A	9.81e-06	4	45	2	16603237
Pubmed	Monocarboxylate transport in human corneal epithelium and cell lines.	SLC16A1 SLC16A7	9.81e-06	4	45	2	20035863
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM3B KDM3A HDAC2	1.07e-05	33	45	3	26864203
Pubmed	Defining the membrane proteome of NK cells.	WRNIP1 KDM3A CAD ATG9A LMBRD2 SLC16A1 CNOT1 CNTRL DHX9	1.57e-05	1168	45	9	19946888
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TXNIP SNRNP27 CHD7 SLC16A1 CNOT1 HDAC2	1.59e-05	418	45	6	34709266
Pubmed	Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44.	SLC16A1 SLC16A7	1.63e-05	5	45	2	20454640
Pubmed	Genetic expression of monocarboxylate transporters during human and murine oocyte maturation and early embryonic development.	SLC16A1 SLC16A7	1.63e-05	5	45	2	12056458
Pubmed	Cysteine 159 delineates a hinge region of the alternating access monocarboxylate transporter 1 and is targeted by cysteine-modifying inhibitors.	SLC16A1 SLC16A7	1.63e-05	5	45	2	33999492
Pubmed	Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture.	SLC16A1 SLC16A7	1.63e-05	5	45	2	39013907
Pubmed	Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.	SLC16A1 SLC16A7	1.63e-05	5	45	2	21787388
Pubmed	Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70).	SLC16A1 SLC16A7	2.45e-05	6	45	2	15917240
Pubmed	H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline.	KDM3B KDM3A	2.45e-05	6	45	2	32679061
Pubmed	A transient placental source of serotonin for the fetal forebrain.	SLC16A1 DDC	3.42e-05	7	45	2	21512572
Pubmed	Localization of members of MCT monocarboxylate transporter family Slc16 in the kidney and regulation during metabolic acidosis.	SLC16A1 SLC16A7	3.42e-05	7	45	2	20392797
Pubmed	Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection.	MERTK TULP1	3.42e-05	7	45	2	22841784
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	CHD7 ZBTB2 CNOT1 DHX9	3.88e-05	146	45	4	23892456
Pubmed	Cited2 is required in trophoblasts for correct placental capillary patterning.	SLC16A1 SLC16A7	4.56e-05	8	45	2	24803182
Pubmed	Distribution of monocarboxylate transporters in the peripheral nervous system suggests putative roles in lactate shuttling and myelination.	SLC16A1 SLC16A7	4.56e-05	8	45	2	25762662
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KDM3B KDM3A CHD7 HDAC2	5.15e-05	157	45	4	30186101
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KDM3B KDM3A CAD SLC16A1 CNOT1 HDAC2	7.27e-05	549	45	6	38280479
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	WRNIP1 KDM3B KDM3A CHD7 CAD SNRPB2 CNOT1 HDAC2	7.58e-05	1103	45	8	34189442
Pubmed	Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.	CAD HDAC2 DHX9	7.98e-05	64	45	3	22865885
Pubmed	Differential patterning of genes involved in serotonin metabolism and transport in extra-embryonic tissues of the mouse.	SLC16A1 DDC	8.94e-05	11	45	2	27238716
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	WRNIP1 CHD7 CAD SLC16A1 HDAC2 DHX9	1.01e-04	583	45	6	29844126
Pubmed	The glucose-lactic acid cycle and gluconeogenesis.	SLC16A1 SLC16A7	1.07e-04	12	45	2	7273846
Pubmed	A functional interaction between the survival motor neuron complex and RNA polymerase II.	SNRPB2 DHX9	1.27e-04	13	45	2	11149922
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CAD SLC16A1 CNOT1 DHX9	1.37e-04	202	45	4	24639526
Pubmed	The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.	SLC16A1 SLC16A7	1.47e-04	14	45	2	12739169
Pubmed	Proteomic analysis of an interactome for long-form AMPA receptor subunits.	CAD DHX9	1.70e-04	15	45	2	20131911
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	WRNIP1 CAD SNRPB2 SLC16A1 CNOT1 AASS HDAC2 DHX9	1.87e-04	1257	45	8	37317656
Pubmed	Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.	B3GALT2 C1GALT1	1.94e-04	16	45	2	10580128
Pubmed	An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.	ZBTB2 CAD DHX9	2.27e-04	91	45	3	20362542
Pubmed	mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.	CAD HDAC2	2.47e-04	18	45	2	14559996
Pubmed	Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa.	MERTK TULP1	2.47e-04	18	45	2	20591486
Pubmed	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	CNTN4 CSMD2	3.38e-04	21	45	2	22449649
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	CNTN4 MERTK MEGF8 TNXB	3.42e-04	257	45	4	16335952
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	ZBTB2 CAD HDAC2	3.56e-04	106	45	3	19394292
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	CAD ATG9A SLC16A1 CNOT1 DHX9	3.95e-04	484	45	5	31995728
Pubmed	Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.	CAD SLC16A1 DHX9	4.29e-04	113	45	3	30352685
Pubmed	The functional interactome landscape of the human histone deacetylase family.	WRNIP1 ZBTB2 CAD HDAC2	5.32e-04	289	45	4	23752268
Pubmed	Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1.	DDC PENK	5.63e-04	27	45	2	20080794
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	CAD SNRPB2 SLC16A1 CNOT1 HDAC2 DHX9	5.85e-04	809	45	6	32129710
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3B PLCB1 KDM3A ERI2 CNOT1	5.91e-04	529	45	5	14621295
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	WRNIP1 PLCB1 CAD SLC16A1 SLC16A7 CNOT1 HDAC2	6.06e-04	1139	45	7	36417873
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	GRIK1 DDC CHRNB3 PENK	6.12e-04	300	45	4	19086053
Pubmed	Determination of genetic predisposition to patent ductus arteriosus in preterm infants.	CHD7 DDC PTGS1	6.31e-04	129	45	3	19336370
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	KDM3B CNTN4 MYO15A CNOT1	6.35e-04	303	45	4	25056061
Pubmed	Genetical genomic determinants of alcohol consumption in rats and humans.	GRIK1 DDC PENK	6.46e-04	130	45	3	19874574
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	KDM3B KDM3A CAD	6.46e-04	130	45	3	35545047
Pubmed	Defining the lineage of thermogenic perivascular adipose tissue.	PTGS1 PENK	6.50e-04	29	45	2	33846639
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	WRNIP1 KDM3B HDAC2	7.05e-04	134	45	3	25452129
Pubmed	FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1.	SNRNP27 CAD SLC16A1	7.68e-04	138	45	3	26752685
Pubmed	The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.	FAM120B CAD CNOT1 AASS	8.25e-04	325	45	4	36168628
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	SNRNP27 ZBTB2 HDAC2 DHX9	8.73e-04	330	45	4	33301849
Pubmed	Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.	KDM3B HDAC2	8.94e-04	34	45	2	30894540
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	WRNIP1 CHD7 SNRPB2 CNOT1 DHX9	9.07e-04	582	45	5	20467437
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	WRNIP1 KDM3B KDM3A HDAC2	9.64e-04	339	45	4	30415952
Pubmed	Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry.	CAD SNRPB2 DHX9	9.96e-04	151	45	3	18457437
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	WRNIP1 CAD DHX9	1.05e-03	154	45	3	16055720
Pubmed	Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.	SNRPB2 SLC16A1 DHX9	1.05e-03	154	45	3	36490346
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	WRNIP1 KDM3B CAD DHX9	1.17e-03	357	45	4	37059091
Pubmed	Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries.	CNTN4 C1GALT1	1.18e-03	39	45	2	24556642
Pubmed	Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.	CHD7 CAD	1.18e-03	39	45	2	25859222
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	WRNIP1 CHD7 CAD CNOT1	1.18e-03	358	45	4	32460013
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	WRNIP1 FAM120B CAD SNRPB2 DHX9	1.24e-03	624	45	5	33729478
GeneFamily	Beta 3-glycosyltransferases	B3GALT2 C1GALT1	7.67e-04	24	31	2	426
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM3B KDM3A	7.67e-04	24	31	2	485
GeneFamily	Fibronectin type III domain containing	CNTN4 MERTK TNXB	2.55e-03	160	31	3	555
Coexpression	GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_DN	TXNIP SLC16A1 AASS PTGS1 PENK	2.35e-05	200	45	5	M5153
Coexpression	GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP	B3GALT2 TXNIP SLC16A7 AASS SPSB1	2.35e-05	200	45	5	M7251
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#1_top-relative-expression-ranked_1000	TXNIP CTSK SLC16A7 TNXB PTGS1	5.63e-06	121	45	5	gudmap_developingLowerUrinaryTract_P1_ureter_1000_k1
ToppCell	droplet-Fat-SCAT-30m-Hematologic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 CNTN4 NEB MYOZ1 DDC	5.82e-07	160	45	5	67ee7a314d7d4d3ea206e0158083f36f6dd7e80b
ToppCell	droplet-Fat-SCAT-30m-Hematologic-erythroblast\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 CNTN4 NEB MYOZ1 DDC	5.82e-07	160	45	5	fc76337ad766c859db390ef8b6fb9caeaace3a56
ToppCell	droplet-Fat-SCAT-30m-Hematologic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 CNTN4 NEB MYOZ1 DDC	5.82e-07	160	45	5	759749f708c3a2b36692d42499f19aff937e592f
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD2 OBP2B CTSK PRSS12	1.14e-05	138	45	4	321070b6900887b27da0f2b25808a05a8ab89ee7
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD2 OBP2B CTSK PRSS12	1.14e-05	138	45	4	19ffd66256fa94d728138d37d0a5a3bac7722dbb
ToppCell	BL-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PLCB1 LMBRD2 AASS PTGS1	2.15e-05	162	45	4	25ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WSCD2 CTSK TNXB PENK	2.31e-05	165	45	4	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TXNIP OBP2B SLC16A1 PRSS12	2.60e-05	170	45	4	8e9b5f7bfb61f8d84d0b17fb0c191da4dabad63d
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ATG9A NEB MEGF8 PTGS1	2.72e-05	172	45	4	f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TXNIP OBP2B SLC16A1 PRSS12	2.91e-05	175	45	4	f949613ee45f5d950578c512d197716855118d18
ToppCell	wk_15-18-Epithelial-PNS-COL20A1+_Schwann\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CNTN4 GRIK1 CSMD2 MYOZ1	3.04e-05	177	45	4	b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCell	droplet-Bladder-nan-24m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 WSCD2 TNXB PENK	3.18e-05	179	45	4	dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TXNIP GRIK1 CHD7 AASS	3.39e-05	182	45	4	3cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TXNIP GRIK1 CHD7 AASS	3.39e-05	182	45	4	5d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TXNIP GRIK1 CHD7 AASS	3.61e-05	185	45	4	efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TXNIP GRIK1 CHD7 AASS	3.61e-05	185	45	4	fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTSK TNXB CHRNB3 PENK	3.61e-05	185	45	4	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTSK TNXB CHRNB3 PENK	3.61e-05	185	45	4	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTSK TNXB CHRNB3 PENK	3.69e-05	186	45	4	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	Severe-MAIT\|World / Disease group and Cell class	B3GALT2 PLCB1 TXNIP CHD7	4.01e-05	190	45	4	7a92e0d6a021be23125495927b8571e25c83204a
ToppCell	Severe-MAIT\|Severe / Disease group and Cell class	B3GALT2 PLCB1 TXNIP CHD7	4.01e-05	190	45	4	1c063dc1b62d9f9912aaf8d0297555a6545f5550
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CNTN4 CTSK TNXB PENK	4.18e-05	192	45	4	cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CNTN4 CTSK TNXB PENK	4.18e-05	192	45	4	29bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTSK TNXB PRSS12 SPSB1	4.26e-05	193	45	4	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTSK TNXB PRSS12 PENK	4.26e-05	193	45	4	160691b671710be10220803d788c2c961c236af1
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CTSK TNXB SPSB1 PENK	4.35e-05	194	45	4	c9e589fe7df6a9b377654581a2aebb607cbb03b9
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PLCB1 TNXB AASS SPSB1	4.44e-05	195	45	4	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	facs-Trachea\|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTSK TNXB SPSB1 PENK	4.53e-05	196	45	4	34020d6553309daa269dff05de0a8567211ea4d2
ToppCell	facs-Trachea\|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CTSK TNXB SPSB1 PENK	4.53e-05	196	45	4	8209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCell	COVID-19-Lymphoid-CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	B3GALT2 PLCB1 TXNIP CHD7	4.53e-05	196	45	4	28515d8e2f02366fa0ac1bea251a7a3f659c98c7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLCB1 MYO15A CSMD2 PENK	4.62e-05	197	45	4	2a90422ba400b951517603a916f34221056d0f3d
ToppCell	Mesenchymal_cells-Arteriolar_fibro.\|Mesenchymal_cells / Lineage and Cell class	CTSK TNXB PRSS12 PENK	4.62e-05	197	45	4	cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Mesothelial-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ATG9A TNXB SPSB1 TULP1	4.71e-05	198	45	4	eb7e674d08a7aeb554c1e4797338280581b79989
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Mesothelial-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATG9A TNXB SPSB1 TULP1	4.71e-05	198	45	4	364de83e30d842123fb92367f54b4bea57a47c84
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Mesothelial-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATG9A TNXB SPSB1 TULP1	4.71e-05	198	45	4	2dc0510846cbc296a300b8465e7be9b39f479852
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CNTN4 GRIK1 CTSK PENK	4.80e-05	199	45	4	6e8a44e46b46e87b81dbfc56fcbbcde166fd00fe
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTN4 GRIK1 CTSK TNXB	4.89e-05	200	45	4	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	Biopsy_IPF-Mesenchymal-HAS1_High_Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	CNTN4 SLC16A1 CTSK TNXB	4.89e-05	200	45	4	d02e256b5d65a5c982ba5696bc7e077281ca3e24
ToppCell	Biopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SLC16A1 CTSK TNXB SPSB1	4.89e-05	200	45	4	0aa316b71f195ecf17ee897e307f8928a755a637
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS12 SPSB1 CHRNB3	2.42e-04	120	45	3	2b7596946f9268c4202348adf3069decd8313bb0
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GRIK1 PTGS1 CHRNB3	2.48e-04	121	45	3	2ae870f822488799cd0ad85e7f72af64e33a867f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nts\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GRIK1 PTGS1 PENK	2.86e-04	127	45	3	ace2944328529fa029ee56c7ad3b0f283511d3bb
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	WSCD2 CNTN4 MYOZ1	3.42e-04	135	45	3	5b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells-Mast-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	B3GALT2 DDC PTGS1	3.49e-04	136	45	3	82d7f90ef2a63a3137c331efd68c036cd0db3ac1
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GALT2 OBP2B DDC	4.56e-04	149	45	3	efa30fcd9370f98eb7445f295eb4d0305ff455c3
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GRIK1 PTGS1 CHRNB3	4.74e-04	151	45	3	090b067873740c282865e2d02cf47d5cb3dd7607
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	B3GALT2 PRSS12 SPSB1	5.02e-04	154	45	3	12cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZBTB2 MERTK NEB	5.31e-04	157	45	3	432b8719a8afd289cf48068e12c26a349d753fcc
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1GALT1 MERTK AASS	5.31e-04	157	45	3	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	B3GALT2 TNXB CNTRL	5.31e-04	157	45	3	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 AASS CHRNB3	5.61e-04	160	45	3	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ERI2 CSMD2 PRSS12	5.61e-04	160	45	3	636127753e3a22831f39d4c8170df40901e4329d
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ERI2 CSMD2 PRSS12	5.61e-04	160	45	3	cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 AASS CHRNB3	5.61e-04	160	45	3	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE4P LMBRD2 MYO15A	5.61e-04	160	45	3	0544bc465af208da448858d6e174ff56f2e08a46
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE4P KDM3A CTSK	5.72e-04	161	45	3	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTSK TNXB PENK	6.14e-04	165	45	3	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	Healthy_Control-Lymphoid-T-innate_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	B3GALT2 PLCB1 SLC16A7	6.14e-04	165	45	3	1ade67229b50fe20eb392262a3e1ee4306b73290
ToppCell	367C-Fibroblasts-Fibroblast-F-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CNTN4 GRIK1 TNXB	6.25e-04	166	45	3	1cc291a04f4144abba4aca7badeb7776db05d903
ToppCell	367C-Fibroblasts-Fibroblast-F\|367C / Donor, Lineage, Cell class and subclass (all cells)	CNTN4 GRIK1 TNXB	6.25e-04	166	45	3	2887f4f0c218cbcbcc82eef27aa4ee714b35cddb
ToppCell	facs-Heart-LV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNXB DDC PENK	6.25e-04	166	45	3	c02c2a68d61dbd7ed086d9b02cfcb1778b8a8656
ToppCell	facs-Heart-LV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNXB DDC PENK	6.25e-04	166	45	3	20c24a9d2eb67a20e5154d25656da14186034f02
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NEB DDC CHRNB3	6.25e-04	166	45	3	6a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZBTB2 MERTK NEB	6.36e-04	167	45	3	b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ZBTB2 NEB AASS	6.58e-04	169	45	3	b1611e61f635f8f9b87250e026ad30999cbee041
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	CNTN4 CTSK TNXB	6.58e-04	169	45	3	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ZBTB2 NEB AASS	6.58e-04	169	45	3	29db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERI2 CNOT1 PTGS1	6.69e-04	170	45	3	12203d4410f38cc933d9f160b5fb76828df94119
ToppCell	facs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERI2 CNOT1 PTGS1	6.69e-04	170	45	3	f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO15A PTGS1 CHRNB3	6.81e-04	171	45	3	e780e63510ca47036bc36ca40ecff4098596ee9e
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 ERI2 DDC	6.81e-04	171	45	3	246fc7edcefc47437d1df6029f295aca3b34b2b2
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 ERI2 DDC	6.81e-04	171	45	3	1fb4e11f92b48dc2d6e553c22e2571bbd8c223c6
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TXNIP MERTK CTSK	6.92e-04	172	45	3	584af6537685cb459bf0fc298e6f46872016c116
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRIK1 SLC16A1 TNXB	7.04e-04	173	45	3	3725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE4P C1GALT1 PENK	7.04e-04	173	45	3	c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRIK1 SLC16A1 TNXB	7.04e-04	173	45	3	ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC16A1 TNXB PRSS12	7.04e-04	173	45	3	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC16A1 TNXB PRSS12	7.16e-04	174	45	3	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	B3GALT2 PRSS12 PTGS1	7.28e-04	175	45	3	f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L6_SST_NPY_(Sst_Chodl)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK1 DDC PENK	7.52e-04	177	45	3	0979e3a9150b3ebc64fe045792a7740a82f7bc2e
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	PLCB1 MERTK CTSK	7.52e-04	177	45	3	470f54fe2b21c7350ea471e02039461a3808f700
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PLCB1 WSCD2 PENK	7.65e-04	178	45	3	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	NEB CTSK TNXB	7.65e-04	178	45	3	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE4P MERTK PTGS1	7.65e-04	178	45	3	6c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE4P B3GALT2 PRSS12	7.65e-04	178	45	3	408e41c853f608965cef9111fb87fdc311cdc7a8
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP OBP2B SLC16A1	7.65e-04	178	45	3	4112ac058e18dedb60e248ca43352fd43f54e77a
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	NEB CTSK TNXB	7.65e-04	178	45	3	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNIP OBP2B SLC16A1	7.65e-04	178	45	3	b2bd45f2fee0b4f7cb9fb7c74109f948d0581785
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRIK1 CTSK TNXB	7.77e-04	179	45	3	dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	B3GALT2 GRIK1 PENK	7.77e-04	179	45	3	ec1d7017da325647b629de703135a404bbdc627d
ToppCell	(3)_Chondrocytes-(32)_Chondro-prehyper-2\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	TXNIP WSCD2 PTGS1	7.90e-04	180	45	3	708a5c89b9337e281fce4f482892a1c1766c7812
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTGS1 SPSB1 PENK	7.90e-04	180	45	3	c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCell	facs-Kidney-nan-24m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTSK TNXB PENK	7.90e-04	180	45	3	f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CTSK TNXB PENK	7.90e-04	180	45	3	c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CTSK TNXB PENK	7.90e-04	180	45	3	32c6a3886428d82fb4355d987c6d2645f333447b
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 FAM120B LMBRD2	8.02e-04	181	45	3	d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT2 FAM120B LMBRD2	8.02e-04	181	45	3	e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCell	(00)_Basal-(0)_uninjured\|(00)_Basal / shred by cell type and Timepoint	TXNIP PTGS1 PENK	8.15e-04	182	45	3	c02c9cab4389d80f318f4bb8d703c1e719672624
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	B3GALT2 CNTN4 PTGS1	8.15e-04	182	45	3	205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CTSK TNXB PENK	8.15e-04	182	45	3	e9fcae9d03a6faf85b91882c5da699037bc61aeb
Disease	hepatitis C virus infection, cirrhosis of liver	MERTK TULP1	4.54e-05	7	44	2	EFO_0001422, EFO_0003047
Disease	cocaine use	GRIK1 CHRNB3	1.19e-04	11	44	2	C3496069
Disease	renal cell carcinoma (biomarker_via_orthology)	CAD PTGS1	1.96e-04	14	44	2	DOID:4450 (biomarker_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	KDM3B KDM3A CHRNB3 HDAC2	2.04e-04	195	44	4	DOID:1574 (implicated_via_orthology)
Disease	Schizophrenia	PLCB1 GRIK1 CSMD2 CTSK TNXB PTGS1 HDAC2	3.06e-04	883	44	7	C0036341
Disease	Leber Congenital Amaurosis	MERTK TULP1	4.93e-04	22	44	2	C0339527
Disease	anxiety disorder (implicated_via_orthology)	KDM3B HDAC2	4.93e-04	22	44	2	DOID:2030 (implicated_via_orthology)
Disease	triacylglycerol 54:8 measurement	PLCB1 CNTN4	5.39e-04	23	44	2	EFO_0010426
Disease	Mental Depression	CSMD2 CHRNB3 HDAC2 PENK	5.55e-04	254	44	4	C0011570
Disease	Alcoholic Intoxication, Chronic	CNTN4 GRIK1 CHRNB3 HDAC2	6.79e-04	268	44	4	C0001973
Disease	Bipolar Disorder	PLCB1 CNTN4 GRIK1 DDC CHRNB3	6.98e-04	477	44	5	C0005586
Disease	Parkinson's disease (biomarker_via_orthology)	DDC PENK	9.21e-04	30	44	2	DOID:14330 (biomarker_via_orthology)
Disease	daytime rest measurement	PLCB1 WSCD2 CNTN4 FAM120B	9.70e-04	295	44	4	EFO_0007828
Disease	Global developmental delay	KDM3B CNOT1 DDC	1.04e-03	133	44	3	C0557874
Disease	lifestyle measurement, anxiety disorder measurement	CSMD2 OBP2B PENK	1.13e-03	137	44	3	EFO_0007795, EFO_0010724
Disease	acute lymphoblastic leukemia (is_marker_for)	KDM3B HDAC2	1.18e-03	34	44	2	DOID:9952 (is_marker_for)
Disease	photoreceptor cell layer thickness measurement	CHD7 SLC16A1 TULP1	1.41e-03	148	44	3	EFO_0803370
Disease	autism spectrum disorder, schizophrenia	KDM3B CNTN4 CNOT1 TNXB	1.42e-03	327	44	4	EFO_0003756, MONDO_0005090

Protein segments in the cluster

Peptide	Gene	Start	Entry
MYNPTGKAAKCRGYR	CTSK	211	P43235
YKLFYRRKPKGLSGA	ERI2	186	A8K979
AKGMKGNRRDGVYSY	CHRNB3	206	Q05901
PYIGKSRYKRNMFAT	CNTRL	386	Q7Z7A1
GAYEYQGKKQPAMLR	CSMD2	3281	Q7Z408
MYRKSDKPLYGNDRF	GRIK1	461	P39086
LRGTLRYKGYMKALN	AASS	721	Q9UDR5
FKKRFMYPVGYGIPA	ADGRE4P	296	Q86SQ3
RGFGYVVAFRPYGKM	CNTN4	731	Q8IWV2
FRMYGVKGLQAYIRK	DDC	366	P20711
MYFKDPQGRVIKGSY	CHD7	1061	Q9P2D1
LAKRYGGFMKRYGGF	PENK	96	P01210
GMFLNYRKIFVGRFK	PABPC1L2A	151	Q5JQF8
GKYFYKRRPLANGLA	SLC16A1	136	P53985
LGYKGPARARTMAYF	PRSS12	541	P56730
GDYYRQGRIAKMPVK	MERTK	751	Q12866
AYKRFGYKLAGMDPE	MYO15A	606	Q9UKN7
GYSGRPRGDLMAYKV	MEGF8	531	Q7Z7M0
FVRPDLGPKMYNAYG	KDM3B	1531	Q7LBC6
GKYFYRKRPMANGLA	SLC16A7	136	O60669
PFNEYRKRFGMKPYT	PTGS1	461	P23219
EPGKYSAYGGRKLMY	OBP2B	86	Q9NPH6
YLMRGYAPNRNKDSK	B3GALT2	281	O43825
FVRPDLGPKMYNAYG	KDM3A	1091	Q9Y4C1
QSRLNRGYKPASKYM	ATG9A	351	Q7Z3C6
GAFYRYKNSMGKSLP	MANEAL	251	Q5VSG8
RRFKPYVKQGYMSGG	C1GALT1	196	Q9NS00
GAGKGKYYAVNFPMR	HDAC2	216	Q92769
GFPFYGKPMRIQYAK	SNRPB2	71	P08579
PPKMARYDNGSGYRR	DHX9	1161	Q08211
GPNKALFYKGMASYL	FAM120B	291	Q96EK7
GAKRGYLLMKTYFKA	LMBRD2	216	Q68DH5
KYRQYMNRKGGFNRP	SNRNP27	136	Q8WVK2
ALRKPFGSKMYYFGI	CNOT1	941	A5YKK6
RDKKGMDRGMYPSYF	TULP1	311	O00294
YMGVAFRGLKGKKLY	SPSB1	196	Q96BD6
PDRKYKMNLYGLRGR	TNXB	1321	P22105
EYNGKSGYRLKPEFM	PLCB1	641	Q9NQ66
AIGAKTYKMRYGNRG	CAD	261	P27708
APTRLMKDLGYGKGY	WRNIP1	621	Q96S55
PSIMKRNGSFPKYYA	ZBTB2	241	Q8N680
PYKALMAEFNRKYGG	WSCD2	421	Q2TBF2
MRPGNKYEYKFGFEL	TXNIP	91	Q9H3M7
PKYKSFNRTAMPYGG	MYOZ1	216	Q9NP98
YNYEKGKGKMVGFRS	NEB	2066	P20929