Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCB7 SLC2A8 SLC6A16 SLC2A7 TTYH2 TMEM63C ABCB6 GRIN2B AQP2 SLC40A1 SLC52A3 CLCN1 SLC45A3 SLC5A6 ATP2C2 SCN10A CACNA1G SLC49A3 LRRC8B SEC63 SLC14A2 SLC22A20P CNGA1 KCNAB3 TRPV5

8.63e-05118018425GO:0022857
GeneOntologyMolecularFunctiontransporter activity

ABCB7 SLC2A8 SLC6A16 SLC2A7 TTYH2 TMEM63C ABCB6 GRIN2B AQP2 SLC40A1 ATP10D SLC52A3 CLCN1 SLC45A3 SLC5A6 ATP2C2 SCN10A CACNA1G SLC49A3 LRRC8B SEC63 SLC14A2 SLC22A20P CNGA1 KCNAB3 TRPV5

1.37e-04128918426GO:0005215
DomainLaminin_G

FAT3 LAMA1 LAMA5 NELL2 FAT2 CNTNAP2 COL14A1

1.47e-06581827IPR001791
Domain-

RAP1GDS1 SARM1 CKAP5 COPG2 ZYG11B PPP4R4 PIK3R4 IPO9 XPO6 HECTD1 TNPO3 ARMC8

1.91e-06222182121.25.10.10
DomainLaminin_G_2

FAT3 LAMA1 LAMA5 NELL2 FAT2 CNTNAP2

2.30e-06401826PF02210
DomainARM-like

RAP1GDS1 SETX SARM1 CKAP5 COPG2 ZYG11B PPP4R4 PIK3R4 IPO9 XPO6 HECTD1 TNPO3 ARMC8

2.56e-0627018213IPR011989
DomainLamG

FAT3 LAMA1 LAMA5 NELL2 FAT2 CNTNAP2

4.09e-06441826SM00282
DomainARM-type_fold

RAP1GDS1 UBR4 SARM1 CKAP5 COPG2 ZYG11B PPP4R4 PIK3R4 IPO9 PIK3C2G XPO6 HECTD1 TNPO3 ARMC8

6.22e-0633918214IPR016024
DomainLAM_G_DOMAIN

FAT3 LAMA1 LAMA5 FAT2 CNTNAP2

3.22e-05381825PS50025
Domain-

FAT3 LAMA1 LAMA5 ADGRV1 NELL2 FAT2 CNTNAP2

3.99e-059518272.60.120.200
DomainTMEM183

TMEM183A TMEM183BP

9.44e-0521822IPR026509
Pubmed

Activation of the oxidative stress pathway by HIV-1 Vpr leads to induction of hypoxia-inducible factor 1alpha expression.

SP1 RELA ROS1

6.19e-074188319204000
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 UXS1 ABCB7 DPY19L1 GNPTAB LAMA1 LGR4 LAMA5 POMGNT1 RELA ITGA7 ITGB5 PDIA4 NELL2 TENM3 FKTN XPO6 SLC5A6 ADGRE5 SEC63 HECTD1 MTCH2

6.56e-0712011882235696571
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

ZHX3 PLBD1 RAP1GDS1 ARHGAP10 TMEM233 POU2F1 RSRC2 PKHD1L1 GARIN2 SLC52A3 NLRP9 NPHP3 NCOA1 HERC6 CTSE XKRX

1.16e-066861881629987050
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

SP1 ABCB7 HTRA2 INPP4A GNPTAB UBR4 POU2F1 ZNF236 ITGB5 PPP4R4 ARHGAP1 ARNT IPO9 FBXL18 INTS2 MTF1 USP7 NCOA1 ALG8 SEC63 HECTD1 ZMYM4

3.33e-0613271882232694731
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

RPLP0 HTRA2 FAT3 LAMA1 TEX15 FAT2 FAM186A USP7 TNPO3

5.68e-06234188936243803
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RAP1GDS1 KDM4C ZCCHC8 GNPTAB UBR4 HECTD4 CKAP5 GRIN2B PIK3R4 ARHGAP1 NELL2 PSMG2 TMEM168 ARHGEF10 GLS USP7 PKNOX1 TNKS HECTD1 ZMYM4 ARMC8

7.03e-0612851882135914814
Pubmed

In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor.

SP1 POU2F1 RELA

8.53e-06818837690421
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

FAT3 CBLN4 GPC3 TENM3 CDH4 EPHA1

1.05e-0591188628558017
Pubmed

Lipid starvation and hypoxia synergistically activate ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer.

SP1 RELA ARNT

1.27e-059188325879517
Pubmed

Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro.

LAMA1 LAMA5 ITGA7

1.81e-0510188318590826
Pubmed

Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.

LAMA1 LAMA5 ITGA7

1.81e-0510188311784026
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

FKBP15 SETX HECTD4 ADGRV1 RBM19 ATP2C2

2.02e-0510218869734811
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

LAMA1 LAMA5 GLI2

2.48e-0511188312051813
Pubmed

The transcription factors Sp1 and Oct-1 interact physically to regulate human U2 snRNA gene expression.

SP1 POU2F1

2.91e-05218828668525
Pubmed

The laminin response in inflammatory bowel disease: protection or malignancy?

LAMA1 LAMA5

2.91e-052188225347196
Pubmed

Identification of two new members, XPLAC and XTES, of the XK family.

XKR3 XKRX

2.91e-052188216431037
Pubmed

Direct downregulation of CNTNAP2 by STOX1A is associated with Alzheimer's disease.

STOX1 CNTNAP2

2.91e-052188222728895
Pubmed

[Correlation between ultrastructural changes of glomerular basement membrane and abnormal distribution of laminins in patients with Alport's syndrome].

LAMA1 LAMA5

2.91e-052188220019771
Pubmed

Effects of hyperosmolality on expression of urea transporter A2 and aquaporin 2 in mouse medullary collecting duct cells.

AQP2 SLC14A2

2.91e-052188222282246
Pubmed

Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene.

SP1 CTSE

2.91e-052188222134960
Pubmed

Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.

RELA SIRT2

2.91e-052188238360128
Pubmed

Molecular interaction between fukutin and POMGnT1 in the glycosylation pathway of alpha-dystroglycan.

POMGNT1 FKTN

2.91e-052188217034757
Pubmed

Transcription factor Sp1 regulates T-type Ca(2+) channel CaV 3.1 gene expression.

SP1 CACNA1G

2.91e-052188223868804
Pubmed

Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux.

SLC40A1 MTF1

2.91e-052188220688958
Pubmed

O-GlcNAc modification of Sp1 inhibits the functional interaction between Sp1 and Oct1.

SP1 POU2F1

2.91e-052188219070619
Pubmed

Presynaptic congenital myasthenic syndrome with a homozygous sequence variant in LAMA5 combines myopia, facial tics, and failure of neuromuscular transmission.

LAMA1 LAMA5

2.91e-052188228544784
Pubmed

Identification of ZCCHC8 as fusion partner of ROS1 in a case of congenital glioblastoma multiforme with a t(6;12)(q21;q24.3).

ZCCHC8 ROS1

2.91e-052188227121553
Pubmed

Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup.

TMEM183A TMEM183BP

2.91e-052188216644869
Pubmed

Integrin alpha 7 interacts with high temperature requirement A2 (HtrA2) to induce prostate cancer cell death.

HTRA2 ITGA7

2.91e-052188220651226
Pubmed

NF-kappaB induced by IL-1beta inhibits elastin transcription and myofibroblast phenotype.

SP1 RELA

2.91e-052188212055073
Pubmed

Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling.

GLI2 NCOA1

2.91e-052188235418691
Pubmed

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle.

CDC14B SIRT2

2.91e-052188212697818
Pubmed

The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.

SP1 ARNT

2.91e-052188216410262
Pubmed

T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro.

POU2F1 LCT

2.91e-052188216301215
Pubmed

Characterization of rhoGAP. A GTPase-activating protein for rho-related small GTPases.

ARHGAP10 ARHGAP1

2.91e-05218828288572
Pubmed

The stability of epigenetic factor ASXL1 is regulated through ubiquitination and USP7-mediated deubiquitination.

ASXL1 USP7

2.91e-052188225836587
Pubmed

Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.

SP1 RPLP0 MTF1

3.30e-051218839582278
Pubmed

Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.

LAMA1 LAMA5 ITGA7

3.30e-0512188311381080
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLXNA3 ZNF384 UBR4 HECTD4 PSMB10 LAMA5 POMGNT1 ZNF236 CDC14B ITGB5 SLC52A3 SIRT2 SLC45A3 XPO6 RBM19 USP7 HECTD1 TNPO3

3.43e-0511051881835748872
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA1 LAMA5 ROS1

5.42e-051418839151674
Pubmed

Genome-wide association study of biochemical traits in Korcula Island, Croatia.

RAP1GDS1 PKNOX1 SLC14A2

5.42e-0514188319260141
Pubmed

Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.

LAMA1 LAMA5 GLI2

5.42e-0514188319783738
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PHYKPL POU6F2 UXS1 CDH26 ARHGAP10 INPP4A TM7SF3 HECTD4 TMEM63C TMEM183BP ADGRV1 ZNF236 CDC14B ITGB5 JMJD1C PPP4R4 PKNOX2 INTS2 GLI2 HECTD1 ZMYM4

6.10e-0514891882128611215
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ASXL1 ABCB7 SETX ARHGAP10 UBR4 CKAP5 POU2F1 RELA CPS1 RSRC2 JMJD1C ARNT L3MBTL3 ZMYM4 ARMC8

7.17e-058571881525609649
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MIER2 KDM4C GNPTAB SARM1 JMJD1C PPP4R4 FAT2 NPHP3 IPO9 GLS HECTD1

8.46e-054931881115368895
Pubmed

Adenovirus preterminal protein binds to the CAD enzyme at active sites of viral DNA replication on the nuclear matrix.

SP1 POU2F1

8.69e-05318829525610
Pubmed

Targeted deletion of CASK-interacting nucleosome assembly protein causes higher locomotor and exploratory activities.

GRIN2B TAF9B

8.69e-053188221576927
Pubmed

Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice.

SP1 USP7

8.69e-053188236759621
Pubmed

In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer's Disease, Major Depressive Disorder, and Type 2 Diabetes.

CPS1 GLS

8.69e-053188229441491
Pubmed

Levels of [(3)H]pirenzepine binding in Brodmann's area 6 from subjects with schizophrenia is not associated with changes in the transcription factor SP1 or BACE1.

SP1 CHRM1

8.69e-053188218790604
Pubmed

RelA-associated inhibitor blocks transcription of human immunodeficiency virus type 1 by inhibiting NF-kappaB and Sp1 actions.

SP1 RELA

8.69e-053188212134007
Pubmed

Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.

FAT3 FAT2

8.69e-053188215744052
Pubmed

Transcriptional regulation of the human CD97 promoter by Sp1/Sp3 in smooth muscle cells.

SP1 ADGRE5

8.69e-053188218329191
Pubmed

The human minor histocompatibility antigen 1 is a RhoGAP.

ARHGAP1 ARHGAP45

8.69e-053188224086303
Pubmed

Deubiquitination of NF-κB by Ubiquitin-Specific Protease-7 promotes transcription.

RELA USP7

8.69e-053188223267096
Pubmed

Overexpression of Sirtuin2 prevents high glucose-induced vascular endothelial cell injury by regulating the p53 and NF-κB signaling pathways.

RELA SIRT2

8.69e-053188229189925
Pubmed

The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis.

ABCB7 ABCB6

8.69e-053188216467350
Pubmed

SLC52A3 expression is activated by NF-κB p65/Rel-B and serves as a prognostic biomarker in esophageal cancer.

RELA SLC52A3

8.69e-053188229428966
Pubmed

Heterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitro.

LAMA1 LAMA5

8.69e-053188210620696
Pubmed

Transcriptional repression of E-cadherin in nickel-exposed lung epithelial cells mediated by loss of Sp1 binding at the promoter.

SP1 ZEB1

8.69e-053188234727382
Pubmed

Prep2: cloning and expression of a new prep family member.

PKNOX2 PKNOX1

8.69e-053188212412021
Pubmed

Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity.

ROPN1B ROPN1

8.69e-053188223303679
Pubmed

Endothelin-1 induces glut1 transcription through enhanced interaction between Sp1 and NF-kappaB transcription factors.

SP1 RELA

8.69e-053188218249093
Pubmed

GLI2 cooperates with ZEB1 for transcriptional repression of CDH1 expression in human melanoma cells.

ZEB1 GLI2

8.69e-053188223890107
Pubmed

GLI2 promotes cell proliferation and migration through transcriptional activation of ARHGEF16 in human glioma cells.

CKAP5 GLI2

8.69e-053188230305138
Pubmed

Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences.

LAMA1 LAMA5

8.69e-05318829006922
Pubmed

Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel.

GRB14 CNGA1

8.69e-053188220890309
Pubmed

Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells.

LAMA1 LAMA5

8.69e-053188212393739
Pubmed

Oncogenic HBXIP enhances ZEB1 through Sp1 to accelerate breast cancer growth.

SP1 ZEB1

8.69e-053188230273966
Pubmed

α1- and α5-containing laminins regulate the development of bile ducts via β1 integrin signals.

LAMA1 LAMA5

8.69e-053188222761447
Pubmed

SP1-activated USP27X-AS1 promotes hepatocellular carcinoma progression via USP7-mediated AKT stabilisation.

SP1 USP7

8.69e-053188238279869
Pubmed

The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination.

HECTD4 GRIN2B

8.69e-053188236527595
Pubmed

NLRC3 deficiency promotes hypoxia-induced pulmonary hypertension development via IKK/NF-κB p65/HIF-1α pathway.

RELA NLRC3

8.69e-053188237586455
Pubmed

Communication between NF-kappa B and Sp1 controls histone acetylation within the proximal promoter of the monocyte chemoattractant protein 1 gene.

SP1 RELA

8.69e-053188212682245
Pubmed

STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide.

SP1 MTF1

8.69e-053188216886906
Pubmed

Regulation of constitutive gene expression through interactions of Sp1 protein with the nuclear aryl hydrocarbon receptor complex.

SP1 ARNT

8.69e-053188210471301
Pubmed

Loss of ASP but not ROPN1 reduces mammalian ciliary motility.

ROPN1B ROPN1

8.69e-053188222021175
Pubmed

Bcl2-associated athanogene 4 promotes the invasion and metastasis of gastric cancer cells by activating the PI3K/AKT/NF-κB/ZEB1 axis.

ZEB1 RELA

8.69e-053188234419501
Pubmed

Involvement of aryl hydrocarbon receptor nuclear translocator in EGF-induced c-Jun/Sp1-mediated gene expression.

SP1 ARNT

8.69e-053188220508969
Pubmed

Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1.

SP1 MTF1

8.69e-053188218990686
Pubmed

Ependymoma-like tumor with mesenchymal differentiation harboring C11orf95-NCOA1/2 or -RELA fusion: A hitherto unclassified tumor related to ependymoma.

RELA NCOA1

8.69e-053188233576087
Pubmed

SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310.

RELA SIRT2

8.69e-053188221081649
Pubmed

Expression of laminin alpha 1, alpha 5 and beta 2 chains during embryogenesis of the kidney and vasculature.

LAMA1 LAMA5

8.69e-05318829049978
Pubmed

Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy.

POMGNT1 FKTN

8.69e-053188219017726
Pubmed

Distinct acidic clusters and hydrophobic residues in the alternative splice domains X1 and X2 of alpha7 integrins define specificity for laminin isoforms.

LAMA1 ITGA7

8.69e-053188217618648
Pubmed

NF-kappaB activation limits airway branching through inhibition of Sp1-mediated fibroblast growth factor-10 expression.

SP1 RELA

8.69e-053188220861353
Pubmed

Compound variants of FKTN, POMGNT1, and LAMB1 gene identified by prenatal whole-exome sequencing in three fetuses with congenital hydrocephalus.

POMGNT1 FKTN

8.69e-053188235843586
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ZNF384 SP1 POU6F2 KDM4C POU2F1 RELA ZNF236 PKNOX2 ARNT SIRT2 TAF9B MTF1 PKNOX1 POLR1B L3MBTL3

9.26e-058771881520211142
Pubmed

Beta1-integrins are critical for cerebellar granule cell precursor proliferation.

LAMA1 LAMA5 ITGA7

1.00e-0417188315056720
Pubmed

Congenital Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

POMGNT1 ITGA7 FKTN

1.00e-0417188320301468
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZEB1 ZCCHC8 INPP4A UBR4 CKAP5 COPG2 JMJD1C GLS L3MBTL3 ZMYM4

1.01e-044181881034709266
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF384 ABCB7 ZEB1 DPY19L1 CKAP5 ITGB5 JMJD1C PDIA4 IPO9 INTS2 GLI2 SLC5A6 TNKS SEC63 HERC4 MTCH2 TNPO3 ZMYM4

1.01e-0412031881829180619
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

RPLP0 SEC24A UBR4 CKAP5 CPS1 PDIA4 IPO9 USP7 HECTD1

1.15e-04344188930333137
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

LAMA1 LAMA5 FREM1

1.19e-0418188314730302
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

HTRA2 UBR4 COQ8B CPS1 PDIA4 SIRT2 GLS HECTD1 QRSL1 ZMYM4 ARMC8

1.24e-045151881131617661
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MIER2 PLXNA3 ZHX3 SP1 ZEB1 KDM4C POU2F1 RELA ZNF236 PKHD1L1 ARNT MTF1 PKNOX1 NCOA1

1.39e-048081881420412781
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

ZNF384 ZCCHC8 UBR4 ARHGAP1 INTS2 USP7 TNPO3 ARMC8

1.60e-04282188823667531
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

UBR4 HECTD4 HERC6 HECTD1 HERC4

1.71e-0495188529643511
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

RAP1GDS1 ARHGAP10 HECTD4 LGR4 LAMA5 ITGA7 CDC14B CACNA1G HERC4

1.73e-04363188914691545
Pubmed

Binding of the ERα and ARNT1 AF2 domains to exon 21 of the SRC1 isoform SRC1e is essential for estrogen- and dioxin-related transcription.

ARNT NCOA1

1.73e-044188222328528
Cytoband12p12

ZNF384 GRIN2B PIK3C2G

1.88e-0513188312p12
Cytoband7q35

PDIA4 CLCN1 CNTNAP2 TRPV5

7.89e-055518847q35
GeneFamilySolute carriers

SLC2A8 SLC6A16 SLC2A7 SLC40A1 SLC52A3 SLC45A3 SLC5A6 SLC49A3 SLC14A2 SLC22A20P MTCH2

1.17e-0439512811752
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP10 ARHGAP1 ARHGAP29 ARHGAP45

4.29e-04501284721
CoexpressionGSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN

AMPD1 DPY19L1 EVI2A ITGB5 INTS2 RBM19 ARHGAP29 XKRX CNGA1 RASGRP2

1.70e-0619918610M9170
CoexpressionNAKAYA_B_CELL_FLUMIST_AGE_18_50YO_7DY_UP

UXS1 INPP4A SEC24A TM7SF3 SARM1 PDIA4 ARHGAP1 ARNT GVINP1 CNTNAP2 PKNOX1 TNKS HERC4 ARMC8

8.23e-0647518614M40979
CoexpressionGSE13762_CTRL_VS_125_VITAMIND_DAY12_DC_UP

UXS1 NIPSNAP3B SEC24A COQ8B STOX1 VIT PKHD1L1 ALG8

1.12e-051481868M1892
CoexpressionGSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN

AMPD1 EVI2A ATP10D ARHGEF10 ADGRE5 CTSE XKRX CNGA1 RASGRP2

1.38e-052001869M7432
CoexpressionGSE7460_TCONV_VS_TREG_LN_UP

ZHX3 SELENOP AMPD1 SETX ARHGAP29 XKRX L3MBTL3 CNGA1 RASGRP2

1.38e-052001869M5673
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ZHX3 ASXL1 ZEB1 SETX KDM4C SEC24A DUSP1 CKAP5 LSM5 PIK3R4 ARHGEF10 XPO6 USP7 ARHGAP29 NCOA1 TNKS HERC4 ZMYM4

4.16e-0585618618M4500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

BOC ZEB1 FAT3 LAMA1 LGR4 GRB14 CDC14B SLC40A1 ITGB5 FREM1 PPP4R4 PKNOX2 CBLN4 GPC3 TENM3 GLI2 COL14A1 CACNA1G CNGA1 MTSS2

1.78e-0579318320gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

BOC DPY19L1 FAT3 LAMA1 LGR4 GRB14 CDC14B ITGB5 FREM1 PPP4R4 PDIA4 PKNOX2 CBLN4 GPC3 TENM3 GLI2 COL14A1 CACNA1G CNGA1

3.78e-0576818319gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

BOC DPY19L1 FAT3 LAMA1 LGR4 GRB14 CDC14B SLC40A1 ITGB5 FREM1 PKNOX2 CBLN4 ARNT GPC3 TENM3 GLI2 COL14A1 CACNA1G RASGRP2

4.13e-0577318319gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasMyeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3

PLBD1 SLC40A1 ITGB5 TREML4 SLC45A3 COL14A1

5.80e-05781836GSM605853_100
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000

BOC PLBD1 DUSP1 FAT3 LAMA1 LGR4 TEX15 CDC14B FREM1 ATP10D PPP4R4 SMPX PKNOX2 GPC3 TENM3 GLI2 ARHGAP29 CACNA1G MTSS2

6.21e-0579718319gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

BOC ZEB1 FAT3 LAMA1 LGR4 TEX15 CDC14B FREM1 ATP10D PPP4R4 SMPX PKNOX2 NELL2 TENM3 GLI2 ARHGAP29 CC2D2A CACNA1G MTSS2

6.21e-0579718319gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

FAT3 LAMA1 LGR4 GRB14 CDC14B ITGB5 FREM1 CBLN4 GPC3 GLI2 COL14A1 CNGA1

7.94e-0536418312gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

FAT3 LAMA1 LGR4 ITGB5 FREM1 PPP4R4 PKNOX2 CBLN4 GPC3 GLI2 COL14A1 CACNA1G

1.00e-0437318312gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500

PLBD1 DUSP1 LGR4 TEX15 FREM1 PPP4R4 PKNOX2 CBLN4 GPC3 GLI2 COL14A1 CNGA1 MTSS2

1.00e-0443218313gudmap_dev gonad_e11.5_M_GonMes_Sma_500
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

FAT3 LAMA1 LGR4 IGSF5 MPDZ TEX15 ITGB5 FREM1 PPP4R4 PKNOX2 CBLN4 GPC3 TENM3 GLI2 ARHGAP29 COL14A1 CACNA1G CNGA1 MTSS2

1.01e-0482718319gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 LAMA1 GRIN2B ADGRV1 CPS1 CHRM1 PKHD1L1 FREM1 PIK3C2G ROS1 SPAG17

4.08e-10184188112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 LAMA1 GRIN2B ADGRV1 CPS1 CHRM1 PKHD1L1 FREM1 PIK3C2G ROS1 SPAG17

4.08e-10184188112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 LAMA1 GRIN2B ADGRV1 CPS1 CHRM1 PKHD1L1 FREM1 PIK3C2G ROS1 SPAG17

4.08e-1018418811ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT3 RSPH6A TOP6BL GRIN2B ADGRV1 CPS1 PKHD1L1 SCN10A ROS1 CNGA1

1.90e-0916218810bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 IGSF5 EVI2A TOP6BL AQP2 SMPX TENM3 SLC14A2 CNGA1

9.33e-091411889091b5b72811db5fca2314f4a79d467566920e257
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 LAMA1 GRIN2B ADGRV1 CPS1 PKHD1L1 FREM1 PIK3C2G CNTNAP2

2.81e-081601889c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 LAMA1 GRIN2B ADGRV1 CPS1 PKHD1L1 FREM1 PIK3C2G CNTNAP2

2.81e-08160188925c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL GRIN2B AQP2 FREM1 PIK3C2G GLS CNGA1 VWA5B1 INPP5J

1.07e-0718718892d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TM7SF3 TOP6BL AQP2 FREM1 TENM3 PIK3C2G SLC14A2 CNGA1 VWA5B1

1.47e-07194188904bfc555743f7d8821439d05ae442d15e9886c59
ToppCell3'_v3-Lung-Myeloid_Mac-Erythrophagocytic_macrophages|Lung / Manually curated celltypes from each tissue

SELENOP MS4A6E TTYH2 TTC36 LCT SLC40A1 B4GALT6 CTSE

9.31e-071781888b63cee443cc1b7416112bf610d7c9d41e4fa37ed
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL GRIN2B AQP2 FREM1 PIK3C2G GLS SPAG17 CNGA1

1.15e-061831888b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

MPDZ ZYG11B FREM1 ATP10D CBLN4 TENM3 COL14A1 SEC63

1.19e-06184188867164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FREM1 SLC52A3 PIK3C2G CNGA1 TRPV5 VWA5B1

1.24e-0618518883d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL FREM1 SLC52A3 PIK3C2G GLS SLC14A2 CNGA1 TRPV5

1.46e-0618918888ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL GRIN2B AQP2 SLC52A3 PIK3C2G GLS CNGA1 INPP5J

1.71e-061931888e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 SLC52A3 PIK3C2G GLS SLC14A2 CNGA1 INPP5J

1.78e-0619418884d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SELENOP TEX15 SLC40A1 FREM1 SMPX GPC3 CNTNAP2 COL14A1

1.78e-06194188899577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FREM1 TENM3 PIK3C2G SLC14A2 CNGA1 VWA5B1

1.78e-06194188869bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGSF5 TOP6BL AQP2 SLC52A3 PIK3C2G SLC14A2 CNGA1 INPP5J

1.78e-061941888be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SELENOP TEX15 SLC40A1 FREM1 SMPX GPC3 CNTNAP2 COL14A1

1.84e-06195188870387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1 CDH4

1.84e-0619518881cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellmild-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AMPD1 SEC24A LAMA5 TOP6BL PKHD1L1 PDIA4 AIFM2 B9D1

1.99e-06197188821085d5e27b5a23a241a933058bb89f8a1fcf198
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1 CDH4

1.99e-06197188831a1852911bda38543916585fda34255fd62a134
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 GLI2 CNTNAP2 COL14A1

1.99e-06197188873a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1 CDH4

1.99e-06197188811a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BOC FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

2.07e-06198188821cf4d81386761d09d0f6829c01c198e5524176d
ToppCellmild-Plasmablast|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AMPD1 SEC24A LAMA5 TOP6BL PKHD1L1 PDIA4 AIFM2 B9D1

2.07e-061981888b14b9e67815f93fac7bd8e5e6f1aa100951b4ac1
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

SELENOP FAT3 SLC40A1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

2.07e-0619818883ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

BOC FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

2.15e-0619918884bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 GLI2 CNTNAP2 COL14A1

2.15e-061991888a09292de4c4447b8eee55d401808e43b817321cc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL FREM1 SLC52A3 PIK3C2G GLS ARHGAP29 TRPV5 INPP5J

2.15e-0619918883cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BOC FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

2.23e-062001888389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRB14 TOP6BL FREM1 PIK3C2G SLC49A3 TRPV5 VWA5B1

3.54e-06150188787968ce885a4959616f0321f58517fe8029ba1b1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL SLC52A3 PIK3C2G GLS SLC14A2 CNGA1 TRPV5

4.03e-06153188779c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM63C TOP6BL SLC52A3 PIK3C2G GLS SLC14A2 TRPV5

5.19e-06159188750d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

INPP4A GRB14 TOP6BL PIK3C2G ATP2C2 VWA5B1 INPP5J

5.41e-061601887174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 GRB14 SLC52A3 PIK3C2G GLS TRPV5 INPP5J

5.87e-06162188736ddebe3bb172c992739353b7b049b2dde98b559
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 FREM1 ATP10D GPC3 COL14A1 VWA5B1

6.89e-06166188765dafed953b01a9830b54309af75c7a561e88336
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

INPP4A GRB14 TOP6BL PIK3C2G ATP2C2 VWA5B1 INPP5J

1.05e-0517718878e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 TMEM233 COQ8B LAMA5 GPC3 SLC45A3 CNGA1

1.17e-05180188741e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FREM1 SLC52A3 PIK3C2G CNGA1 INPP5J

1.30e-051831887d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL FREM1 SLC52A3 PIK3C2G SLC14A2 TRPV5 INPP5J

1.44e-051861887d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL FREM1 SLC52A3 PIK3C2G SLC14A2 TRPV5 INPP5J

1.44e-05186188708632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

TOP6BL AQP2 FREM1 PIK3C2G SPAG17 CNGA1 TRPV5

1.55e-0518818878f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SELENOP FAT3 SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1

1.60e-051891887203c80030df08ae112f9ae4043709f455d87ce89
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FREM1 PIK3C2G CNGA1 VWA5B1 INPP5J

1.60e-051891887a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FREM1 PIK3C2G GLS CNGA1 VWA5B1

1.60e-051891887532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL FREM1 PIK3C2G GLS SLC14A2 CNGA1 TRPV5

1.66e-0519018874836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ARHGAP10 FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2

1.66e-0519018873a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SELENOP FAT3 SLC40A1 NELL2 CBLN4 GPC3 COL14A1

1.66e-05190188771e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

1.71e-051911887b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC PLXNA3 AQP2 ITGB5 GPC3 TENM3 COL14A1

1.71e-0519118874b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SELENOP SLC40A1 CBLN4 GPC3 CNTNAP2 COL14A1 CDH4

1.71e-051911887fa380a8752de158974b2ae5e741573439719cc0d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL FREM1 TENM3 PIK3C2G SLC14A2 CNGA1 VWA5B1

1.71e-0519118873e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC PLXNA3 AQP2 ITGB5 GPC3 TENM3 COL14A1

1.71e-05191188775d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 PIK3C2G GLS ARHGAP29 HECTD1 CNGA1

1.77e-0519218872510f22197502f60fd266b7f42eff040f25b8ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 PIK3C2G GLS ARHGAP29 HECTD1 CNGA1

1.77e-051921887e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 SLC52A3 PIK3C2G GLS SLC14A2 CNGA1

1.77e-0519218870bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 SLC52A3 PIK3C2G SLC14A2 CNGA1 INPP5J

1.77e-05192188740f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

1.77e-0519218874e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

1.77e-051921887deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellCOVID-19_Severe-Plasmablast|COVID-19_Severe / disease group, cell group and cell class

SEC24A TOP6BL PKHD1L1 PDIA4 AIFM2 B9D1 POLQ

1.83e-0519318878074bcede261b85f9ae03ee372bd6d4b40384537
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

CKAP5 POU2F1 ADGRV1 POLR1B LRRC8B HECTD1 ZMYM4

1.83e-051931887abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

FAT3 SLC40A1 FREM1 PKNOX2 GPC3 TENM3 GLI2

1.83e-051931887ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SELENOP SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1 CDH4

1.89e-0519418875f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

1.89e-0519418876e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

1.89e-05194188789b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SELENOP FAT3 FREM1 PKNOX2 GPC3 GLI2 CNTNAP2

1.89e-051941887011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FREM1 PIK3C2G SLC14A2 CNGA1 VWA5B1

1.89e-0519418874579b4a44f7c731553a284843c296866027d7c0e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

1.89e-05194188760622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FREM1 PIK3C2G SLC14A2 CNGA1 VWA5B1

1.96e-0519518873d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1

2.02e-0519618871450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

BOC FAT3 FREM1 PKNOX2 GPC3 GLI2 COL14A1

2.02e-051961887bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-GMP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CDH26 RPLP0 GNPTAB TM7SF3 B4GALT6 PDIA4 RASGRP2

2.09e-051971887462e91dc51e363d64e1e02d7444a733838e032a5
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1

2.09e-0519718870034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1

2.16e-05198188717dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC ADGRV1 PPP4R4 ARHGAP29 CDH4 SLC14A2

2.17e-051331886f303ab771482281d8793974f9f5279cee09431fe
ToppCellwk_08-11-Mesenchymal-Fibroblast-intermediate_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SELENOP FAT3 SLC40A1 FREM1 GPC3 CNTNAP2 COL14A1

2.23e-051991887f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LAMA1 TTYH2 SLC40A1 FREM1 GPC3 TENM3 COL14A1

2.23e-051991887a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CERKL ARHGAP10 FAT3 GRB14 PPP4R4 PIK3C2G ROS1

2.30e-0520018878821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

2.30e-052001887cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3|Neuronal / cells hierarchy compared to all cells using T-Statistic

CERKL ARHGAP10 FAT3 GRB14 PPP4R4 PIK3C2G ROS1

2.30e-052001887ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

CERKL ARHGAP10 FAT3 GRB14 PPP4R4 PIK3C2G ROS1

2.30e-0520018879c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCellwk_20-22-Mesenchymal-Fibroblast-intermediate_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SELENOP SLC40A1 SMPX CBLN4 GPC3 CNTNAP2 COL14A1

2.30e-052001887d769723f8fcb37d9b86589e0c41c1d7f16393cfe
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

2.30e-052001887cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--|Neuronal / cells hierarchy compared to all cells using T-Statistic

CERKL ARHGAP10 FAT3 GRB14 PPP4R4 PIK3C2G ROS1

2.30e-05200188796b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT3 FREM1 PKNOX2 GPC3 TENM3 GLI2 COL14A1

2.30e-052001887311fab076f2ceb258e3970eb21e39344b894042a
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOP6BL GRIN2B ADGRV1 CPS1 SCN10A ROS1

3.53e-05145188696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FREM1 PIK3C2G ROS1 CNGA1

4.43e-051511886f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPH6A PPP4R4 SMPX ATP2C2 CNTNAP2 SCN10A

6.11e-051601886c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPH6A PPP4R4 SMPX ATP2C2 CNTNAP2 SCN10A

6.11e-05160188641d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRB14 TOP6BL FREM1 PIK3C2G TRPV5 VWA5B1

7.25e-0516518869bd332e5ede759a00a47728ea5558c215efdd77a
ToppCellremission-HSPC|World / disease stage, cell group and cell class

NIPSNAP3B TM7SF3 LGR4 SLC40A1 SLC45A3 MTSS2

7.49e-051661886d269ee6f7adb55b05dcb5eaea96629ccb0b2d6e3
ToppCellICU-NoSEP-Lymphocyte-T_NK-MAIT|ICU-NoSEP / Disease, Lineage and Cell Type

SLC6A16 ARHGAP10 TMEM63C POMGNT1 MAGEE1 B4GALT6

7.49e-051661886d3fa2e42497201f1ca57f4f977fbaa0def950033
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLBD1 EVI2A CDC14B B4GALT6 ALG8 HERC6

8.00e-05168188693b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLBD1 EVI2A CDC14B B4GALT6 ALG8 HERC6

8.00e-051681886e393553208617a023f1646169c892a87c95db3f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

INPP4A GRB14 TOP6BL PIK3C2G ATP2C2 VWA5B1

8.27e-0516918862a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCellCOVID-19_Convalescent-Hematopoietic_SC|COVID-19_Convalescent / Disease group, lineage and cell class

SELENOP NIPSNAP3B LGR4 SLC40A1 SLC45A3 MTSS2

8.54e-0517018868a73d5334eed1cd9fdcc3ebeae0bdf9f945c228a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOP6BL AQP2 FAT2 PIK3C2G GLS SPAG17

8.54e-051701886928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM233 VIT ITGA7 PPP4R4 TENM3 CACNA1G

8.82e-051711886fdd96c6fe850bd10e1e0d0f18c4401f8348b7d2c
DrugPinacidil [85371-64-8]; Up 200; 16.4uM; HL60; HT_HG-U133A

KDM4C LCT TLR8 SMPX NELL2 ARNT FBXL18 HERC4 KCNAB3 ZMYM4 MTSS2

8.66e-07199188112406_UP
DrugMeptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; HL60; HT_HG-U133A

GNPTAB UBR4 MPDZ ITGB5 PPP4R4 FBXL18 GPC3 B9D1 KCNAB3 EPHA1

5.37e-06195188102906_UP
DrugReserpinic acid hydrochloride; Up 200; 9.2uM; MCF7; HT_HG-U133A

ZHX3 ZEB1 TEX15 ARNT RBM19 GLS SCN10A HERC4 INPP5J RASGRP2

5.88e-06197188104948_UP
DiseaseMeckel-Gruber syndrome

NPHP3 B9D1 CC2D2A

2.68e-05101823cv:C0265215
DiseaseDown syndrome (biomarker_via_orthology)

RPLP0 RPLP0P6

3.78e-0521822DOID:14250 (biomarker_via_orthology)
DiseaseCongenital muscular dystrophy

POMGNT1 ITGA7 FKTN

4.87e-05121823cv:C0699743
DiseasePolydactyly

NPHP3 GPC3 GLI2 B9D1 CC2D2A ARMC8

9.00e-051171826C0152427
Diseasecysteine-rich hydrophobic domain-containing protein 2 measurement

SARM1 PPP4R4

1.13e-0431822EFO_0801510
Diseaseretinitis pigmentosa (is_implicated_in)

CERKL POMGNT1 CC2D2A CNGA1

1.19e-04411824DOID:10584 (is_implicated_in)
DiseaseMeckel syndrome type 1

NPHP3 B9D1 CC2D2A

1.76e-04181823C3714506
DiseaseGastrointestinal Stromal Sarcoma

BOC GLI2 B9D1 CC2D2A

2.03e-04471824C3179349
DiseaseGastrointestinal Stromal Tumors

BOC GLI2 B9D1 CC2D2A

2.58e-04501824C0238198
DiseaseWalker-Warburg syndrome (is_implicated_in)

POMGNT1 FKTN

3.74e-0451822DOID:0050560 (is_implicated_in)
Diseasepolycystic liver disease (is_implicated_in)

ALG8 SEC63

3.74e-0451822DOID:0050770 (is_implicated_in)
DiseasePolycystic liver disease

ALG8 SEC63

3.74e-0451822C0158683
DiseaseLimb-girdle muscular dystrophy

POMGNT1 FKTN TNPO3

5.41e-04261823cv:C0686353
Diseasetorsin-1A-interacting protein 1 measurement

SELENOP SARM1

5.58e-0461822EFO_0802137
DiseaseFailure to Thrive

TCN2 SLC5A6

5.58e-0461822C0015544
DiseaseNephroblastoma

POU6F2 GPC3

1.03e-0381822cv:C0027708
DiseaseHereditary Wilms tumor

POU6F2 GPC3

1.03e-0381822cv:C0677779
DiseaseKidney Wilms tumor

POU6F2 GPC3

1.03e-0381822cv:CN305775
Diseasemuscular dystrophy-dystroglycanopathy type B1 (implicated_via_orthology)

POMGNT1 FKTN

1.03e-0381822DOID:0050588 (implicated_via_orthology)
Diseasearteriosclerosis (biomarker_via_orthology)

RELA ITGA7

1.03e-0381822DOID:2349 (biomarker_via_orthology)
Diseasedynein light chain roadblock-type 1 measurement

SARM1 CDC14B

1.03e-0381822EFO_0008114
Diseasebreast cancer anti-estrogen resistance protein 3 measurement

SARM1 JMJD1C

1.03e-0381822EFO_0008040
Diseasecathepsin S measurement

GNPTAB ARNT

1.03e-0381822EFO_0008073
Diseaseacid sphingomyelinase-like phosphodiesterase 3a measurement

GNPTAB SARM1

1.03e-0381822EFO_0008013
DiseaseMicrophthalmia associated with colobomatous cyst

ABCB6 TENM3

1.03e-0381822C2931501
DiseaseAlcohol withdrawal syndrome

KDM4C MPDZ

1.03e-0381822C0236663
DiseaseMeckel syndrome (implicated_via_orthology)

B9D1 CC2D2A

1.03e-0381822DOID:0050778 (implicated_via_orthology)
DiseaseAutistic Disorder

POU6F2 TCN2 GRIN2B SLC40A1 JMJD1C MTF1 CNTNAP2

1.23e-032611827C0004352
Diseaseglycosyl-N-stearoyl-sphingosine (d18:1/18:0) measurement

ATP10D CNGA1

1.32e-0391822EFO_0800275
DiseaseNephroblastoma

ASXL1 POU6F2 GPC3

1.42e-03361823C0027708
Diseasevesicular integral-membrane protein VIP36 measurement

SARM1 ITGB5

1.65e-03101822EFO_0022012
DiseaseColorectal Neoplasms

BOC SELENOP TCN2 LAMA1 ABCB6 ARNT EPHA1

1.73e-032771827C0009404
DiseaseProfound Mental Retardation

ZCCHC8 INPP4A LAMA1 GRIN2B CACNA1G

1.75e-031391825C0020796
DiseaseMental Retardation, Psychosocial

ZCCHC8 INPP4A LAMA1 GRIN2B CACNA1G

1.75e-031391825C0025363
DiseaseMental deficiency

ZCCHC8 INPP4A LAMA1 GRIN2B CACNA1G

1.75e-031391825C0917816
Diseasegastrin-releasing peptide measurement

SARM1 JMJD1C

2.01e-03111822EFO_0022000
DiseaseDisorder of eye

CERKL ADGRV1 FREM1 NPHP3 CC2D2A CNGA1

2.09e-032121826C0015397
Diseasecomplement factor D measurement

KDM4C SARM1 XKR3 CNTNAP2

2.67e-03931824EFO_0020283
Diseasefibrinogen measurement, tissue plasminogen activator measurement

HECTD4 CPS1 JMJD1C

2.71e-03451823EFO_0004623, EFO_0004791
Diseasefibrinogen measurement, plasminogen activator inhibitor 1 measurement

HECTD4 CPS1 JMJD1C

2.71e-03451823EFO_0004623, EFO_0004792
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

SELENOP SARM1

2.82e-03131822EFO_0802114
DiseaseSquamous cell carcinoma of esophagus

TCN2 FAT3 SLC52A3 FAT2

2.88e-03951824C0279626
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

MPDZ ARHGAP45 VWA5B1

3.26e-03481823EFO_0009268, MONDO_0001627, MONDO_0004975
DiseaseMUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K

POMGNT1 FKTN

3.28e-03141822C1836373
Diseasenephroblastoma (is_implicated_in)

POU6F2 GPC3

3.28e-03141822DOID:2154 (is_implicated_in)
Diseasealpha-Dystroglycanopathies

POMGNT1 FKTN

3.28e-03141822C2936406
DiseaseFukuyama Type Congenital Muscular Dystrophy

POMGNT1 FKTN

3.28e-03141822C0410174
DiseaseMuscle eye brain disease

POMGNT1 FKTN

3.28e-03141822C0457133
DiseaseAutosomal recessive limb-girdle muscular dystrophy

POMGNT1 FKTN

3.28e-03141822cv:C2931907
DiseaseMuscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1

POMGNT1 FKTN

3.28e-03141822C4284790
DiseaseEndometrioma

SELENOP DUSP1 SLC40A1 ARNT NCOA1

3.30e-031611825C0269102
DiseaseEndometriosis

SELENOP DUSP1 SLC40A1 ARNT NCOA1

3.30e-031611825C0014175
DiseaseWalker-Warburg congenital muscular dystrophy

POMGNT1 FKTN

3.77e-03151822C0265221
DiseaseMeckel-Gruber syndrome

B9D1 CC2D2A

3.77e-03151822C0265215
Diseasecortical thickness

ZHX3 SP1 FAT3 TM7SF3 LAMA1 LGR4 ADGRV1 STOX1 VIT ITGB5 JMJD1C NELL2 GLS B9D1 MTCH2

3.90e-03111318215EFO_0004840
DiseasePre-Eclampsia

STOX1 ARHGAP45

4.29e-03161822C0032914
DiseaseColorectal Carcinoma

BOC SELENOP AMPD1 TCN2 LAMA1 ABCB6 ARNT PKNOX1 SPAG17 ZMYM4 EPHA1

4.38e-0370218211C0009402
DiseaseEpilepsy

GRIN2B CHRM1 SLC5A6 CNTNAP2

4.71e-031091824C0014544
DiseaseIschemic stroke, fibrinogen measurement

HECTD4 CPS1 JMJD1C

4.79e-03551823EFO_0004623, HP_0002140
Diseasemuscular dystrophy (is_implicated_in)

POMGNT1 FKTN

4.84e-03171822DOID:9884 (is_implicated_in)
DiseaseCiliopathies

ADGRV1 NPHP3 B9D1 CC2D2A

4.86e-031101824C4277690
Diseasedisease free survival

CHRM1 CNTNAP2

5.42e-03181822EFO_0000409
Diseasefibrinogen measurement, factor VII measurement

HECTD4 CPS1 JMJD1C

5.55e-03581823EFO_0004619, EFO_0004623
Diseaseadverse effect, response to xenobiotic stimulus

TMEM233 LAMA1 COL14A1

5.82e-03591823EFO_0009658, GO_0009410
DiseaseMalignant neoplasm of skin

SP1 RELA GLI2

5.82e-03591823C0007114
DiseaseSkin Neoplasms

SP1 RELA GLI2

5.82e-03591823C0037286
DiseaseSjogren syndrome

C3orf20 NCOA1 TNPO3

6.10e-03601823EFO_0000699

Protein segments in the cluster

PeptideGeneStartEntry
VNGLVALMNSNVSSP

UXS1

306

Q8NBZ7
IVQPSASAGQMLAQI

ARNT

611

P27540
LVPGQLVAMLQGIAS

EPHA1

721

P21709
QMGQIAIVSFQNSTP

ARHGEF10

931

O15013
QALPSVLQIAMAFGL

AQP2

36

P41181
QVATQLGMFSPIALQ

CELF3

186

Q5SZQ8
SVIGPQQQFLVMKQT

CDC14B

351

O60729
NLTLINIFGENPSEM

GVINP1

1571

Q7Z2Y8
PAVAGILSIQNMTTL

ADGRE5

396

P48960
LAETNLQVTVMVPFN

ADGRV1

1221

Q8WXG9
LQDVSFTVMPGQTLA

ABCB6

606

Q9NP58
SPQLLVAAAQQTLGM

C1orf74

11

Q96LT6
NIFMPVFEATINPQA

AMPD1

481

P23109
TVFNLPSPLNAMQIL

ATP2C2

751

O75185
ATSVGSFLMQLLGQQ

PHYKPL

336

Q8IUZ5
VEATNPLVMQLLQGS

ASXL1

1101

Q8IXJ9
QVMVDFAALGPLTFQ

ATP10D

751

Q9P241
PFVLVSNLMAVNNCG

MTCH2

236

Q9Y6C9
TLFMGPNAVADAIAQ

RBM19

516

Q9Y4C8
FINANPMGKNISIIF

PIK3C2G

906

O75747
NPMVNAGAIVVTSLI

GLS

331

O94925
IQSGMLLRVQPVLFN

INPP4A

786

Q96PE3
NQNITVIPSGFRVGM

L3MBTL3

361

Q96JM7
QNLMTVANLGVVFGP

ARHGAP10

526

A1A4S6
QAVGTLQTQTFMQPL

ARHGAP45

356

Q92619
NRPGNNFLMQVLSFI

MAGEE1

831

Q9HCI5
QDVQLLVMPQGFIAQ

NELL2

206

Q99435
TNQFQDPVMELLGSV

NLRC3

646

Q7RTR2
LMSAVQPLNISQVFD

GNPTAB

1001

Q3T906
QLQNFNTLMAVVGGL

RASGRP2

236

Q7LDG7
NNIFAIIPAILMGVS

SLC2A7

111

Q6PXP3
VVAMLLSLDFPGQAQ

GPC3

11

P51654
FPTMNGVSQVLQNVL

JMJD1C

1946

Q15652
NLNVMPDVTFTINGV

CTSE

316

P14091
LQNPIVTQFFPSVML

TMEM63C

446

Q9P1W3
INTPMQINGNFCGLV

PLXNA3

376

P51805
SINQDTGMIQTLAPL

FAT2

1081

Q9NYQ8
ITFLQPVVNGELTML

MTSS2

201

Q765P7
QLTGPNLVMQSTGVL

EVI2A

201

P22794
LFQPNELQAMVIGNT

HERC4

931

Q5GLZ8
VTGLQAPSAALMQVS

FKBP15

431

Q5T1M5
PITNFSQMDVVGQTV

FREM1

1451

Q5H8C1
FSAVPVNNTQVMQII

INTS2

761

Q9H0H0
VAINNNRGFVSPMLT

HERC6

1006

Q8IVU3
VSQQNMLLIPASFSP

NIPSNAP3B

231

Q9BS92
PGAIVFAILAAMSIQ

DPY19L1

501

Q2PZI1
NGMVQVSFSGVPAQL

PLK5

271

Q496M5
APIQQMVTGQSGLFT

KDM4C

71

Q9H3R0
NRLINGLVASNIFPM

LCT

1001

P09848
LVIRGASMVQQFPNL

LGR4

301

Q9BXB1
PTFLAQQPMALTSIN

GLI2

321

P10070
VLQGNQMSITFLEPA

LAMA5

1736

O15230
MQQNNSVPEFILLGL

OR4C11

1

Q6IEV9
ITQLSFQLISEPMFG

OVOS2

166

Q6IE36
QAVQSMLLPQEGSLS

HECTD4

1821

Q9Y4D8
NMLNISPFSFGLVIQ

RPLP0

176

P05388
NTPNAMTILLAVVGS

ITGB5

716

P18084
VAILNTSVAPMLNPF

OR6C76

271

A6NM76
KPMTLFQIQFLNSVG

PLBD1

186

Q6P4A8
VLPEQLSTMQLEGFQ

LRRC8B

521

Q6P9F7
QILLNGNNITMLVPG

LSM5

71

Q9Y4Y9
AIPQTQLMLAGGQIT

POU2F1

96

P14859
FILSQPQLGQAVVIM

MOGAT3

176

Q86VF5
ATVSGMNLLNTVLPV

PROSER1

301

Q86XN7
IGIQEFMPLQSLFTN

ARHGAP29

251

Q52LW3
AFENPQVSMTLVNVL

ARMC8

216

Q8IUR7
LNILQQLAVAMGPNI

CKAP5

921

Q14008
PLFVNVNDQTNEGIM

CPS1

351

P31327
ATLMLPTQTISQGAI

CPS1

1206

P31327
PVFAQTFQQTMLPSI

HECTD1

526

Q9ULT8
FVVAMGSPFALQNTI

HTRA2

256

O43464
GTMPATNVSIFINNT

IGSF11

96

Q5DX21
LTVQVMGELFIPSVN

IGSF5

136

Q9NSI5
NYLIMPSGNLQIVNA

BOC

176

Q9BWV1
NNAPLMQLISVATSG

CC2D2A

866

Q9P2K1
QTGTQPFNRAMLFNV

B4GALT6

196

Q9UBX8
ALLDTVMQALPQVGN

CACNA1G

1731

O43497
FMGQLLQFESQVLAP

DUSP1

301

P28562
DIFTQAVNMAGLPAV

QRSL1

446

Q9H0R6
IGTVMVPGSQNNLLL

COL14A1

781

Q05707
LANMSAIGVNSPYQL

C3orf20

211

Q8ND61
SNAVQIVGMSATLPN

POLQ

256

O75417
QPVAGTNQLDMLFAV

FAT3

3691

Q8TDW7
SLQAQLINMGVIPTL

RAP1GDS1

171

P52306
QVNLMLNGKPVISAF

CBLN4

136

Q9NTU7
TVMVSNQAPLASGIQ

CDH4

471

P55283
QFLSQPIITFGTAMA

CHRM1

181

P11229
IQGQFLNVSIMAIPC

CERKL

421

Q49MI3
VGQMLSIQDNSFISP

COQ8B

156

Q96D53
EAVNNIITFLGMQPC

COPG2

796

Q9UBF2
FIMLTSNQNVPVFLI

FKTN

61

O75072
IIMLPSNVINFSQAE

MS4A6E

11

Q96DS6
ENQSAGQPIFQMLAV

CDH26

176

Q8IXH8
TVAMSPELIQQFLQA

IPO9

506

Q96P70
NGEISPTQILQMFLS

GRB14

216

Q14449
SVLQPSFQGCMQLIQ

CNTNAP2

511

Q9UHC6
LSIAGMAIPQQLFFS

ITGA7

851

Q13683
LGMPLTTQQAQELGI

FAM186A

1371

A6NE01
PSVFLLMVNGQVESA

B9D1

6

Q9UPM9
LVQALFGIINTPAML

SLC22A20P

371

A6NK97
IVVPASALQQGNIAM

PKNOX2

216

Q96KN3
EIMVGPQFQADLSNL

MIER2

196

Q8N344
GALQVLSQLTPQTVM

KCNAB3

376

O43448
FVSPPMLESNFIQVN

GARIN2

41

Q8N9W8
AITQLLTQMPALVGA

RTL1

1141

A6NKG5
GSLSQQENLLMPQVF

RSPH6A

61

Q9H0K4
TTAVQNVLINPSMIG

TAF9B

201

Q9HBM6
TMAAGPNSILFAINI

SNX29P2

11

Q8IUI4
NMLNISPFSFGLVIQ

RPLP0P6

176

Q8NHW5
VVNLPTDLFNSVMNV

ROPN1B

96

Q9BZX4
ALLASGTQVTPQIAM

RSRC2

281

Q7L4I2
PINIVALVFSIMSLN

TMEM233

51

B4DJY2
IMQGIITPLQDTFSF

SLC6A16

516

Q9GZN6
LVAFVNALTNGMLPS

SLC52A3

306

Q9NQ40
GTSVIANLPFLMRQN

PPP4R4

71

Q6NUP7
QTMDPQGQTLLLFLF

TOP6BL

316

Q8N6T0
AASQLQALNVPFMLV

AIFM2

26

Q9BRQ8
PSIGSMIQLQQSFRG

NPHP3

241

Q7Z494
VPASALQQGNVAMAT

PKNOX1

191

P55347
QVTTLNFIFIPIVMG

TMEM183BP

296

Q1AE95
YGLQESLSQPQMLIV

SEC24A

556

O95486
ISSQMGPVLQAAISI

SLC5A6

416

Q9Y289
AMVQTLPLGANSVLT

MTF1

531

Q14872
ILNQFAATAPVGINM

NCOA1

1076

Q15788
SLLSAQGVSPQMITV

POMGNT1

321

Q8WZA1
AAAGGIMTLPLQNLQ

POU6F2

156

P78424
AILSGQLMVGQSNVP

FBXL18

211

Q96ME1
PFIIGVSLMAFQQLS

SLC2A8

256

Q9NY64
VTQIIMLFNTFSPNG

LAMA1

2326

P25391
KMTNTNLAVVFGPNL

ARHGAP1

386

Q07960
GQLMDPIVAFQTIIN

SETX

306

Q7Z333
LLLVMGTSLQVQPFA

SIRT2

256

Q8IXJ6
DQLTNILAPMAVGQI

SLC40A1

181

Q9NP59
SQGQLVVMQPEKFQS

PDIA4

351

P13667
FQPNMTLEAAQGLLV

PSMB10

181

P40306
VTVNAAQLSSMPGLQ

SP1

516

P08047
PMLNSNGSVTVVALL

SELENOP

41

P49908
LSQVAPSLFMGSIVQ

SLC45A3

501

Q96JT2
PSLFMGSIVQLSQSV

SLC45A3

506

Q96JT2
VGFNNPQLLAIMAEL

SPAG17

226

Q6Q759
GAFQNALMISQLLPV

TCN2

281

P20062
VMVNGLLFQLSLPLN

ABCB7

411

O75027
MTSGLVQQFQHTVLP

ALG8

316

Q9BVK2
LQQIADFMTTNVPNV

ADD1

91

P35611
INTQQSFVTMPNVIV

CNGA1

6

P29973
VAVILANMVAQSLQP

CLCN1

561

P35523
VVQPQTLLTQVGIFM

NLRP9

481

Q7RTR0
LGPFNFVLVSSVRMQ

INPP5J

491

Q15735
MGNQLAGIAPSQILS

PIK3R4

1

Q99570
LATMSNPLGVLVANV

SLC49A3

166

Q6UXD7
MQLPNLSTINLGINF

TLR8

391

Q9NR97
AFIQQRPSMQFVGLL

ZYG11B

286

Q9C0D3
IPTVSGQIENTMFIN

ZNF384

16

Q8TF68
DGPILQILFMNNAIS

ZCCHC8

91

Q6NZY4
KPNAGFFNITMIQLT

TREML4

86

Q6UXN2
QVTTLNFIFIPIVMG

TMEM183A

296

Q8IXX5
AGNPVVFMVQSIINR

MPDZ

1231

O75970
QVLPEDMQAVLTFNG

SARM1

666

Q6SZW1
PTFEAMLQIGNIVFT

SCN10A

691

Q9Y5Y9
TMQIQVAGLLQFAVP

TTYH2

321

Q9BSA4
VFPVQMNPITQSQFV

STOX1

106

Q6ZVD7
VVNLPTDLFNSVMNV

ROPN1

96

Q9HAT0
VRAIQANINIPMGAF

SMPX

11

Q9UHP9
DPSIISLQGFTAAQM

TNKS

616

O95271
GTTAQPVTLMQLLAV

VIT

176

Q6UXI7
QMAVQGLQQFKSPLL

SEC63

371

Q9UGP8
NQFISQQPPVVSSIM

TENM3

1136

Q9P273
FLNISGTMLNVPELQ

ROS1

626

P08922
QPTNGIFLSMFLIVL

TMEM168

376

Q9H0V1
PIQFISNGTTGQMQL

PKHD1L1

4001

Q86WI1
LQATSSPQGMVQAVV

ZEB1

381

P37275
TNLPLAMQLFQGVLT

TNPO3

261

Q9Y5L0
GSAALLQPLVTQMVN

TNPO3

676

Q9Y5L0
MGTPNDQAVLQAIFN

TTC36

1

A6NLP5
MSVIQAFLGSVPQLI

XKR3

166

Q5GH77
PNVFIMNNSVLTGQF

ZNF236

1306

Q9UL36
TLLMPAVSVGNVGQL

PSMG2

16

Q969U7
NIITGNFLMGPLNLT

TEX15

1311

Q9BXT5
VQMGVPFTEQIIQTF

XPO6

851

Q96QU8
NQEVLTPGQLFLMFL

POLR1B

371

Q9H9Y6
MSQIQAFLGSVPQLT

XKRX

171

Q6PP77
FLSTMKQNALQGVVP

UBR4

786

Q5T4S7
MVFPSGQISQASALA

RELA

366

Q04206
LVTQPLMANGLQATS

ZHX3

426

Q9H4I2
TAQVMFINNPLSGLI

SLC14A2

126

Q15849
VQSLSQTMGFPQDQI

USP7

606

Q93009
MNSSVVPLSQGQVIV

ZMYM4

621

Q5VZL5
NTNGEVVPMSFALVL

TRPV5

446

Q9NQA5
ILFVANLGTIAPMEN

VWA5B1

126

Q5TIE3
NLGTIAPMENVTIFI

VWA5B1

131

Q5TIE3
GIQPVQNMAILLSYS

TM7SF3

116

Q9NS93
FGPSIEQQASVMLNI

GRIN2B

146

Q13224