Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein tyrosine kinase activity	ABL2 EPHA6 NTRK1 TEC ZAP70 MST1R EPHA2 EPHA5	5.49e-06	145	132	8	GO:0004713
GeneOntologyMolecularFunction	ephrin receptor activity	EPHA6 NTRK1 EPHA2 EPHA5	6.55e-06	19	132	4	GO:0005003
GeneOntologyMolecularFunction	nerve growth factor receptor activity	NTRK1 SORT1	4.34e-05	2	132	2	GO:0010465
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	EPHA6 NTRK1 MST1R EPHA2 EPHA5	7.03e-05	65	132	5	GO:0004714
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	EPHA6 NTRK1 MST1R EPHA2 EPHA5	2.51e-04	85	132	5	GO:0019199
GeneOntologyMolecularFunction	neurotrophin receptor activity	NTRK1 SORT1	4.28e-04	5	132	2	GO:0005030
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	TMEM67 SYNRG ATP8B4 ATP6AP1 SLC11A2 MAP6 NTRK1 SLC6A17 KIF1B TMEM59 SLC44A2 LAMP2 ITGA2B OLR1 SORT1 PTPRB ABCA5 VNN1 DISP3 APPL1 MFSD10 RAB5C SORL1 TMEM63A	2.05e-06	1307	132	24	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	TMEM67 SYNRG ATP8B4 ATP6AP1 SLC11A2 MAP6 NTRK1 SLC6A17 KIF1B TMEM59 SLC44A2 LAMP2 ITGA2B OLR1 SORT1 PTPRB ABCA5 VNN1 DISP3 APPL1 MFSD10 RAB5C SORL1 TMEM63A	2.60e-06	1325	132	24	GO:0012506
GeneOntologyCellularComponent	lysosomal membrane	ATP6AP1 SLC11A2 ENPP1 TMEM59 SLC44A2 LAMP2 SORT1 ABCA5 VNN1 RAB5C TMEM63A	1.71e-04	462	132	11	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	ATP6AP1 SLC11A2 ENPP1 TMEM59 SLC44A2 LAMP2 SORT1 ABCA5 VNN1 RAB5C TMEM63A	1.71e-04	462	132	11	GO:0098852
GeneOntologyCellularComponent	cell surface	SLC11A2 ENPP1 NTRK1 SLITRK3 ITGA2B DCC F2 SORT1 MST1R LIFR FCGR3A EPHA2 TNN CLEC2D ABCC2 IGSF3 EPHA5 SORL1	2.19e-04	1111	132	18	GO:0009986
GeneOntologyCellularComponent	secretory granule membrane	ATP8B4 SLC44A2 LAMP2 ITGA2B OLR1 PTPRB VNN1 RAB5C TMEM63A	2.47e-04	329	132	9	GO:0030667
GeneOntologyCellularComponent	specific granule membrane	ATP8B4 SLC44A2 OLR1 PTPRB TMEM63A	2.80e-04	91	132	5	GO:0035579
GeneOntologyCellularComponent	receptor complex	NTRK1 KCTD8 ITGA2B OLR1 ZAP70 MST1R LIFR PTPRB EPHA2 KCTD16 EPHA5 TRAV13-2	3.20e-04	581	132	12	GO:0043235
GeneOntologyCellularComponent	vacuolar membrane	ATP6AP1 SLC11A2 ENPP1 TMEM59 SLC44A2 LAMP2 SORT1 ABCA5 VNN1 RAB5C TMEM63A	3.79e-04	507	132	11	GO:0005774
GeneOntologyCellularComponent	Golgi-associated vesicle	SYNRG MAP6 SORT1 PACS1 CLRN1	7.88e-04	114	132	5	GO:0005798
GeneOntologyCellularComponent	late endosome membrane	SLC11A2 NTRK1 TMEM59 LAMP2 ABCA5 SORL1	9.74e-04	179	132	6	GO:0031902
GeneOntologyCellularComponent	tertiary granule membrane	ATP8B4 OLR1 PTPRB TMEM63A	1.18e-03	73	132	4	GO:0070821
GeneOntologyCellularComponent	endosome membrane	ATP6AP1 SLC11A2 NTRK1 TMEM59 LAMP2 SORT1 ABCA5 APPL1 RAB5C SORL1 TMEM63A	1.54e-03	602	132	11	GO:0010008
GeneOntologyCellularComponent	nuclear membrane	ZC3HC1 SORT1 SYNE2 NUP133 DISP3 UGT2B15 UGT2B17 MFSD10	1.71e-03	349	132	8	GO:0031965
GeneOntologyCellularComponent	brush border membrane	TRPM6 SLC11A2 ABCC2 MFSD10	1.90e-03	83	132	4	GO:0031526
GeneOntologyCellularComponent	trans-Golgi network transport vesicle	SYNRG SORT1 CLRN1	2.05e-03	40	132	3	GO:0030140
GeneOntologyCellularComponent	nuclear outer membrane	SYNE2 UGT2B15 UGT2B17	2.05e-03	40	132	3	GO:0005640
GeneOntologyCellularComponent	early endosome membrane	SLC11A2 NTRK1 APPL1 RAB5C SORL1 TMEM63A	2.30e-03	212	132	6	GO:0031901
Domain	Tyr_kinase_cat_dom	ABL2 EPHA6 NTRK1 TEC ZAP70 MST1R EPHA2 EPHA5	1.79e-07	88	130	8	IPR020635
Domain	TyrKc	ABL2 EPHA6 NTRK1 TEC ZAP70 MST1R EPHA2 EPHA5	1.79e-07	88	130	8	SM00219
Domain	Pkinase_Tyr	ABL2 EPHA6 NTRK1 TEX14 TEC ZAP70 MST1R EPHA2 EPHA5	2.94e-07	129	130	9	PF07714
Domain	PROTEIN_KINASE_TYR	ABL2 EPHA6 NTRK1 TEC ZAP70 MST1R EPHA2 EPHA5	3.81e-07	97	130	8	PS00109
Domain	Tyr_kinase_AS	ABL2 EPHA6 NTRK1 TEC ZAP70 MST1R EPHA2 EPHA5	3.81e-07	97	130	8	IPR008266
Domain	Ser-Thr/Tyr_kinase_cat_dom	ABL2 EPHA6 NTRK1 TEX14 TEC ZAP70 MST1R EPHA2 EPHA5	5.22e-07	138	130	9	IPR001245
Domain	fn3	EPHA6 DCC LIFR FNDC1 PTPRB EPHA2 TNN EPHA5 SORL1	2.00e-06	162	130	9	PF00041
Domain	FN3	EPHA6 DCC LIFR FNDC1 PTPRB EPHA2 TNN EPHA5 SORL1	5.94e-06	185	130	9	SM00060
Domain	FN3	EPHA6 DCC LIFR FNDC1 PTPRB EPHA2 TNN EPHA5 SORL1	1.07e-05	199	130	9	PS50853
Domain	-	EPHA6 TRIO NTRK1 DCC PKHD1L1 MST1R LIFR FNDC1 PTPRB FCGR3A EPHA2 TNN EXOC2 IGSF3 EPHA5 SORL1	1.50e-05	663	130	16	2.60.40.10
Domain	FN3_dom	EPHA6 DCC LIFR FNDC1 PTPRB EPHA2 TNN EPHA5 SORL1	1.58e-05	209	130	9	IPR003961
Domain	Ig-like_fold	EPHA6 TRIO NTRK1 DCC PKHD1L1 MST1R LIFR FNDC1 PTPRB FCGR3A EPHA2 TNN EXOC2 IGSF3 EPHA5 SORL1	3.23e-05	706	130	16	IPR013783
Domain	RECEPTOR_TYR_KIN_V_2	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	PS00790
Domain	Tyr_kinase_rcpt_V_CS	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	IPR001426
Domain	EphA2_TM	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	IPR001090
Domain	Eph_TM	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	IPR027936
Domain	EPH_lbd	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	SM00615
Domain	Ephrin_lbd	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	IPR016257
Domain	EPH_LBD	EPHA6 EPHA2 EPHA5	1.13e-04	14	130	3	PS51550
Domain	Glyco_transf_64	EXTL1 EXTL3	4.74e-04	5	130	2	PF09258
Domain	Sortilin_C	SORT1 SORL1	4.74e-04	5	130	2	PF15901
Domain	Sortilin-Vps10	SORT1 SORL1	4.74e-04	5	130	2	PF15902
Domain	VPS10	SORT1 SORL1	4.74e-04	5	130	2	IPR006581
Domain	Sortilin_N	SORT1 SORL1	4.74e-04	5	130	2	IPR031778
Domain	Sortilin_C	SORT1 SORL1	4.74e-04	5	130	2	IPR031777
Domain	Exostosin	EXTL1 EXTL3	4.74e-04	5	130	2	PF03016
Domain	VPS10	SORT1 SORL1	4.74e-04	5	130	2	SM00602
Domain	Exostosin	EXTL1 EXTL3	4.74e-04	5	130	2	IPR004263
Domain	EXT_C	EXTL1 EXTL3	4.74e-04	5	130	2	IPR015338
Domain	Ephrin_rec_like	EPHA6 EPHA2 EPHA5	6.78e-04	25	130	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHA6 EPHA2 EPHA5	6.78e-04	25	130	3	IPR011641
Domain	Kinesin-like	KIF1B RABGAP1L	7.08e-04	6	130	2	IPR022164
Domain	DUF3694	KIF1B RABGAP1L	7.08e-04	6	130	2	PF12473
Domain	TIG	PKHD1L1 MST1R EXOC2	1.28e-03	31	130	3	PF01833
Domain	IPT	PKHD1L1 MST1R EXOC2	1.41e-03	32	130	3	IPR002909
Domain	Kinase-like_dom	TRPM6 ABL2 EPHA6 TRIO NTRK1 TEX14 TEC ZAP70 MST1R EPHA2 EPHA5	1.44e-03	542	130	11	IPR011009
Domain	-	TRIO SH3BP2 DOCK9 KIF1B ECT2L TEC RABGAP1L APPL1 MTMR9	1.68e-03	391	130	9	2.30.29.30
Domain	-	EPHA6 EPHA2 CPXM1 EPHA5	1.68e-03	73	130	4	2.60.120.260
Domain	Phosphodiest/P_Trfase	PIGN ENPP1	2.09e-03	10	130	2	IPR002591
Domain	Phosphodiest	PIGN ENPP1	2.09e-03	10	130	2	PF01663
Domain	Prot_kinase_dom	ABL2 EPHA6 TRIO NTRK1 TEX14 TEC ZAP70 MST1R EPHA2 EPHA5	2.24e-03	489	130	10	IPR000719
Domain	PROTEIN_KINASE_DOM	ABL2 EPHA6 TRIO NTRK1 TEX14 TEC ZAP70 MST1R EPHA2 EPHA5	2.37e-03	493	130	10	PS50011
Domain	DHR-1_domain	DOCK3 DOCK9	2.54e-03	11	130	2	IPR027007
Domain	DHR_2	DOCK3 DOCK9	2.54e-03	11	130	2	PS51651
Domain	DHR_1	DOCK3 DOCK9	2.54e-03	11	130	2	PS51650
Domain	DHR-2	DOCK3 DOCK9	2.54e-03	11	130	2	PF06920
Domain	DOCK	DOCK3 DOCK9	2.54e-03	11	130	2	IPR026791
Domain	DOCK_C	DOCK3 DOCK9	2.54e-03	11	130	2	IPR010703
Domain	DOCK-C2	DOCK3 DOCK9	2.54e-03	11	130	2	PF14429
Domain	DHR-2	DOCK3 DOCK9	2.54e-03	11	130	2	IPR027357
Domain	Kinesin_motor_CS	KIF21B KIF1B KIF20B	2.90e-03	41	130	3	IPR019821
Domain	PH_dom-like	TRIO SH3BP2 DOCK9 KIF1B ECT2L TEC RABGAP1L APPL1 MTMR9	2.98e-03	426	130	9	IPR011993
Domain	Kinesin-like_fam	KIF21B KIF1B KIF20B	3.32e-03	43	130	3	IPR027640
Domain	-	KIF21B KIF1B KIF20B	3.54e-03	44	130	3	3.40.850.10
Domain	Kinesin	KIF21B KIF1B KIF20B	3.54e-03	44	130	3	PF00225
Domain	KISc	KIF21B KIF1B KIF20B	3.54e-03	44	130	3	SM00129
Domain	KINESIN_MOTOR_1	KIF21B KIF1B KIF20B	3.54e-03	44	130	3	PS00411
Domain	Kinesin_motor_dom	KIF21B KIF1B KIF20B	3.54e-03	44	130	3	IPR001752
Domain	KINESIN_MOTOR_2	KIF21B KIF1B KIF20B	3.54e-03	44	130	3	PS50067
Domain	Galactose-bd-like	EPHA6 EPHA2 CPXM1 EPHA5	4.22e-03	94	130	4	IPR008979
Domain	Growth_fac_rcpt_	TMEM67 EPHA6 EPHA2 TNN EPHA5	4.73e-03	156	130	5	IPR009030
Domain	PROTEIN_KINASE_ATP	ABL2 EPHA6 TRIO NTRK1 TEC ZAP70 MST1R EPHA2 EPHA5	4.85e-03	459	130	9	PS00107
Domain	Protein_kinase_ATP_BS	ABL2 EPHA6 NTRK1 TEC ZAP70 MST1R EPHA2 EPHA5	5.07e-03	379	130	8	IPR017441
Domain	PH	TRIO SH3BP2 DOCK9 KIF1B TEC APPL1	5.38e-03	229	130	6	PF00169
Domain	SH2	ABL2 SH3BP2 TEC ZAP70	5.44e-03	101	130	4	PF00017
Domain	BTB_2	KCTD8 KCTD16 KCNS1	5.99e-03	53	130	3	PF02214
Domain	T1-type_BTB	KCTD8 KCTD16 KCNS1	5.99e-03	53	130	3	IPR003131
Pubmed	Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer.	KRT5 AKR1C3 UGT2B15 UGT2B17	3.14e-09	6	134	4	21365123
Pubmed	The protein tyrosine kinase family of the human genome.	EPHA6 NTRK1 TEC ZAP70 MST1R EPHA2 EPHA5	3.50e-08	83	134	7	11114734
Pubmed	Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families.	APOA5 SORT1 SORL1	5.59e-08	3	134	3	18603531
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	PIGN TMEM67 ATP6AP1 SPOCK1 ENPP1 TMEM59 LAMP2 EXTL3 MBOAT2 FANCA SORT1 MST1R LIFR EPHA2 PRKCSH TMEM258 RAB5C IGSF3 SORL1	1.91e-07	1201	134	19	35696571
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	KRT5 NTRK1 SLITRK3 MST1R PTPRB EPHA2 ADAM5 HERC1 MTMR9 EPHA5	5.71e-06	420	134	10	28065597
Pubmed	Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate.	EPHA6 EPHA2 EPHA5	6.58e-06	10	134	3	25073978
Pubmed	EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes.	EPHA6 EPHA2 EPHA5	6.58e-06	10	134	3	16547242
Pubmed	HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.	EPHA6 EPHA2 EPHA5	6.58e-06	10	134	3	17304517
Pubmed	Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice.	EPHA6 EPHA2 EPHA5	9.02e-06	11	134	3	24550361
Pubmed	Integral and associated lysosomal membrane proteins.	SLC11A2 ENPP1 SLC44A2 LAMP2 RAB5C TMEM63A	9.86e-06	126	134	6	17897319
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	KRT5 ATP6AP1 TRIO WDR55 SORT1 BLMH PACS1 ARL2 PTPRB SYNE2 NUP133 PRKCSH HERC1 ADGRL2 MTMR9	1.36e-05	1049	134	15	27880917
Pubmed	Regulation of coenzyme A levels by degradation: the 'Ins and Outs'.	ENPP1 VNN1	1.47e-05	2	134	2	32234503
Pubmed	Thrombin-anti-thrombin levels and patency of arterio-venous fistula in patients undergoing haemodialysis compared to healthy volunteers: a prospective analysis.	F2 SERPINC1	1.47e-05	2	134	2	23844096
Pubmed	A fragment of antithrombin that binds both heparin and thrombin.	F2 SERPINC1	1.47e-05	2	134	2	3800906
Pubmed	Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.	UGT2B15 UGT2B17	1.47e-05	2	134	2	32660355
Pubmed	The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.	UGT2B15 UGT2B17	1.47e-05	2	134	2	1909870
Pubmed	Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.	UGT2B15 UGT2B17	1.47e-05	2	134	2	24121496
Pubmed	The site in human antithrombin for functional proteolytic cleavage by human thrombin.	F2 SERPINC1	1.47e-05	2	134	2	7238875
Pubmed	Disease-causing mutations in the serpin antithrombin reveal a key domain critical for inhibiting protease activities.	F2 SERPINC1	1.47e-05	2	134	2	28743742
Pubmed	Interpreting coronary artery disease GWAS results: A functional genomics approach assessing biological significance.	SORT1 LIPA	1.47e-05	2	134	2	35192625
Pubmed	Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.	UGT2B15 UGT2B17	1.47e-05	2	134	2	24267955
Pubmed	Heparin-induced substrate behavior of antithrombin Cambridge II.	F2 SERPINC1	1.47e-05	2	134	2	12907439
Pubmed	Site-directed mutagenesis of alanine-382 of human antithrombin III.	F2 SERPINC1	1.47e-05	2	134	2	2013320
Pubmed	Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.	UGT2B15 UGT2B17	1.47e-05	2	134	2	22170718
Pubmed	Germline FOXJ2 overexpression causes male infertility via aberrant autophagy activation by LAMP2A upregulation.	FOXJ2 LAMP2	1.47e-05	2	134	2	35908066
Pubmed	Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.	UGT2B15 UGT2B17	1.47e-05	2	134	2	3105095
Pubmed	UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.	UGT2B15 UGT2B17	1.47e-05	2	134	2	17848572
Pubmed	Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.	UGT2B15 UGT2B17	1.47e-05	2	134	2	27496708
Pubmed	Markers of hemostatic system activation during treatment of deep vein thrombosis with subcutaneous unfractionated or low-molecular weight heparin.	F2 SERPINC1	1.47e-05	2	134	2	11927130
Pubmed	AlphaIIbbeta3 and its antagonism at the new millennium.	ITGA2B F2	1.47e-05	2	134	2	11487023
Pubmed	The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.	UGT2B15 UGT2B17	1.47e-05	2	134	2	17698910
Pubmed	Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein.	NTRK1 SORT1	1.47e-05	2	134	2	22128158
Pubmed	Specificity of signal transduction through CD16, TCR-CD3 and BCR receptor chains containing the tyrosine-associated activation motif.	ZAP70 FCGR3A	1.47e-05	2	134	2	7819147
Pubmed	Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.	UGT2B15 UGT2B17	1.47e-05	2	134	2	3117546
Pubmed	Activated αIIbβ3 on platelets mediates flow-dependent NETosis via SLC44A2.	SLC44A2 ITGA2B	1.47e-05	2	134	2	32314961
Pubmed	Mediation of the DCC apoptotic signal by DIP13 alpha.	DCC APPL1	1.47e-05	2	134	2	12011067
Pubmed	Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis.	EXTL1 EXTL3	1.47e-05	2	134	2	11390981
Pubmed	Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.	UGT2B15 UGT2B17	1.47e-05	2	134	2	28228532
Pubmed	Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.	UGT2B15 UGT2B17	1.47e-05	2	134	2	15666817
Pubmed	Eph-ephrin A system regulates murine blastocyst attachment and spreading.	EPHA6 EPHA2 EPHA5	1.55e-05	13	134	3	17039519
Pubmed	EphA family gene expression in the developing mouse neocortex: regional patterns reveal intrinsic programs and extrinsic influence.	EPHA6 EPHA2 EPHA5	1.55e-05	13	134	3	12528186
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	NTRK1 MST1R EPHA2 EPHA5	1.73e-05	40	134	4	30898150
Pubmed	Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue.	EPHA6 EPHA2 EPHA5	1.97e-05	14	134	3	26941654
Pubmed	A role for the EphA family in the topographic targeting of vomeronasal axons.	EPHA6 EPHA2 EPHA5	1.97e-05	14	134	3	11222144
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PIGN ABL2 SLC6A17 FANCA SORT1 C18orf21 RARS2 PRKCSH ABCC2 HERC1 TMEM258 IGSF3	2.36e-05	719	134	12	35337019
Pubmed	A quantitative protein interaction network for the ErbB receptors using protein microarrays.	ABL2 SH3BP2 TEC ZAP70 APPL1	2.66e-05	90	134	5	16273093
Pubmed	Quantitative proteomics identifies a Dab2/integrin module regulating cell migration.	MST1R EPHA2 ABCC2 IGSF3	2.78e-05	45	134	4	19581412
Pubmed	Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.	EPHA6 EPHA2 EPHA5	3.02e-05	16	134	3	8755474
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHA6 EPHA2 EPHA5	3.66e-05	17	134	3	12217323
Pubmed	Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.	UGT2B15 UGT2B17	4.41e-05	3	134	2	19572376
Pubmed	Association Between LOX-1, LAL, and ACAT1 Gene Single Nucleotide Polymorphisms and Carotid Plaque in a Northern Chinese Population.	OLR1 LIPA	4.41e-05	3	134	2	32101051
Pubmed	Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.	UGT2B15 UGT2B17	4.41e-05	3	134	2	26385605
Pubmed	Targeted next-generation sequencing panel screening of 668 Chinese patients with non-obstructive azoospermia.	TEX14 TEX11	4.41e-05	3	134	2	33728612
Pubmed	Expression of two novel eph-related receptor protein tyrosine kinases in mammary gland development and carcinogenesis.	EPHA2 EPHA5	4.41e-05	3	134	2	8152808
Pubmed	SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes.	PACS1 SORL1	4.41e-05	3	134	2	24001769
Pubmed	Distribution of the auxiliary GABAB receptor subunits KCTD8, 12, 12b, and 16 in the mouse brain.	KCTD8 KCTD16	4.41e-05	3	134	2	21452234
Pubmed	Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.	EPHA6 EPHA5	4.41e-05	3	134	2	27582484
Pubmed	Aldo-keto reductase 1C3 is expressed in differentiated human epidermis, affects keratinocyte differentiation, and is upregulated in atopic dermatitis.	KRT5 AKR1C3	4.41e-05	3	134	2	22170488
Pubmed	KCTD8 and KCTD12 Facilitate Axonal Expression of GABAB Receptors in Habenula Cholinergic Neurons.	KCTD8 KCTD16	4.41e-05	3	134	2	35017224
Pubmed	Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.	UGT2B15 UGT2B17	4.41e-05	3	134	2	26163549
Pubmed	Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.	UGT2B15 UGT2B17	4.41e-05	3	134	2	20736324
Pubmed	Neurotrophin Receptors TrkA, p75NTR, and Sortilin Are Increased and Targetable in Thyroid Cancer.	NTRK1 SORT1	4.41e-05	3	134	2	29037860
Pubmed	A genetic risk score is significantly associated with statin therapy response in the elderly population.	SORT1 ABCC2	4.41e-05	3	134	2	27943270
Pubmed	Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis.	SORT1 SORL1	4.41e-05	3	134	2	32712736
Pubmed	Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival.	EPHA2 EPHA5	4.41e-05	3	134	2	16737551
Pubmed	Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.	UGT2B15 UGT2B17	4.41e-05	3	134	2	28882566
Pubmed	ProNGF increases breast tumor aggressiveness through functional association of TrkA with EphA2.	NTRK1 EPHA2	4.41e-05	3	134	2	30771434
Pubmed	Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer.	SORT1 APPL1	4.41e-05	3	134	2	36089417
Pubmed	Sortilin and SorLA regulate neuronal sorting of trophic and dementia-linked proteins.	SORT1 SORL1	4.41e-05	3	134	2	22297619
Pubmed	Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.	UGT2B15 UGT2B17	4.41e-05	3	134	2	17988216
Pubmed	Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.	UGT2B15 UGT2B17	4.41e-05	3	134	2	23223495
Pubmed	GGA autoinhibition revisited.	SORT1 SORL1	4.41e-05	3	134	2	20015111
Pubmed	Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.	UGT2B15 UGT2B17	4.41e-05	3	134	2	18302198
Pubmed	The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.	UGT2B15 UGT2B17	4.41e-05	3	134	2	30689982
Pubmed	Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein.	SORT1 SORL1	4.41e-05	3	134	2	23283322
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHA6 EPHA2 EPHA5	5.18e-05	19	134	3	12684176
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	LAMP2 ITGA2B F2 FGL2 VNN1 TNN SERPINC1	6.56e-05	257	134	7	16335952
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	KIF21B RABGAP1L IGSF3 TMEM63A	6.62e-05	56	134	4	9455484
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHA6 EPHA2 EPHA5	7.07e-05	21	134	3	9267020
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHA6 EPHA2 EPHA5	7.07e-05	21	134	3	11128993
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHA6 EPHA2 EPHA5	7.07e-05	21	134	3	10495276
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHA6 EPHA2 EPHA5	7.07e-05	21	134	3	20112066
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHA6 EPHA2 EPHA5	7.07e-05	21	134	3	10730216
Pubmed	Enhanced plasticity of retinothalamic projections in an ephrin-A2/A5 double mutant.	EPHA2 EPHA5	8.80e-05	4	134	2	11567058
Pubmed	Exploring the human genome with functional maps.	ATP6AP1 LAMP2	8.80e-05	4	134	2	19246570
Pubmed	A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.	FNDC1 LIPA	8.80e-05	4	134	2	21606135
Pubmed	The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function.	NTRK1 KIF1B	8.80e-05	4	134	2	27263974
Pubmed	The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding.	SORT1 SORL1	8.80e-05	4	134	2	11821067
Pubmed	A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes.	EPHA6 EPHA2	8.80e-05	4	134	2	10607706
Pubmed	Impaired "outside-in" integrin alphaIIbbeta3 signaling and thrombus stability in TSSC6-deficient mice.	ITGA2B F2	8.80e-05	4	134	2	16720835
Pubmed	Mapping of Abll within a conserved linkage group on distal mouse chromosome 1 syntenic with human chromosome 1 using an interspecific cross.	ABL2 SERPINC1	8.80e-05	4	134	2	2567701
Pubmed	Expression analysis of genes encoding TEX11, TEX12, TEX14 and TEX15 in testis tissues of men with non-obstructive azoospermia.	TEX14 TEX11	8.80e-05	4	134	2	29932616
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE2 TMEM258	8.80e-05	4	134	2	28716842
Pubmed	Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation.	SORT1 SORL1	8.80e-05	4	134	2	18480253
Pubmed	Ephrin-A2 and ephrin-A5 guide contralateral targeting but not topographic mapping of ventral cochlear nucleus axons.	EPHA2 EPHA5	8.80e-05	4	134	2	26666565
Pubmed	Sortilin is essential for proNGF-induced neuronal cell death.	NTRK1 SORT1	8.80e-05	4	134	2	14985763
Pubmed	Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits.	KCTD8 KCTD16	8.80e-05	4	134	2	20400944
Pubmed	SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1.	PACS1 SORL1	8.80e-05	4	134	2	17855360
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	TMEM67 SYNE2	8.80e-05	4	134	2	19596800
Pubmed	Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.	UGT2B15 UGT2B17	8.80e-05	4	134	2	18281521
GeneFamily	Fibronectin type III domain containing	EPHA6 DCC LIFR FNDC1 PTPRB EPHA2 TNN EPHA5 SORL1	1.95e-07	160	97	9	555
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA6 EPHA2 EPHA5	5.22e-05	14	97	3	1095
GeneFamily	Exostosin glycosyltransferase family	EXTL1 EXTL3	2.82e-04	5	97	2	431
GeneFamily	Maestro heat like repeat containing	MROH5 MROH1	1.52e-03	11	97	2	636
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF1B KIF20B	1.92e-03	46	97	3	622
GeneFamily	C-type lectin domain family	OLR1 CLEC2D CLEC2A	2.05e-03	47	97	3	494
GeneFamily	SH2 domain containing	ABL2 SH3BP2 TEC ZAP70	2.14e-03	101	97	4	741
Coexpression	ASTON_MAJOR_DEPRESSIVE_DISORDER_DN	TRIO SPOCK1 KIF1B MCM7 LAMP2 LIPA EPHA5 TMEM63A	1.57e-06	160	132	8	M11011
Coexpression	GSE40493_BCL6_KO_VS_WT_TREG_UP	TRIO EXTL3 SORT1 SETDB1 GUF1 UBA6 APPL1 USP47	3.33e-06	177	132	8	M9401
Coexpression	GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN	SLC11A2 DOCK9 F2 MBOAT2 ZAP70 LIPA HERC1	3.67e-05	180	132	7	M6878
Coexpression	MEK_UP.V1_UP	ST6GALNAC2 PACS1 EPHA2 AKR1C3 ADGRL2 RAB5C SORL1	6.09e-05	195	132	7	M2725
Coexpression	GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP	ENPP1 SH3BP2 KIF1B RFTN2 MBOAT2 ST6GALNAC2 SYNE2	6.71e-05	198	132	7	M9778
Coexpression	GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP	KIF21B SYNRG DOCK9 ZAP70 SYNE2 CLEC2D TMEM63A	6.71e-05	198	132	7	M4478
Coexpression	GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP	EXTL1 LIFR PACS1 PLA2G4C TNN SERPINC1 TMEM63A	6.92e-05	199	132	7	M6079
Coexpression	GSE3982_MAST_CELL_VS_DC_UP	FOXJ2 TRMT9B KIF21B TRIO NTRK1 PRKCSH TMEM258	6.92e-05	199	132	7	M5426
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN	TRPM6 OLR1 ZAP70 ST6GALNAC2 ARL2 PDE5A SORL1	6.92e-05	199	132	7	M4348
Coexpression	GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	KIF21B ATP8B4 LIPA SYNE2 PDE5A SORL1 TMEM63A	7.15e-05	200	132	7	M7432
Coexpression	GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN	EXTL1 SORT1 LIPA SYNE2 UGT2B17 ADGRL2 RAB5C	7.15e-05	200	132	7	M6610
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY10 DOCK3 EPHA6 PKHD1L1 ABCA5 ABCC2 EPHA5	6.16e-07	162	134	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 ZAP70 FANCA LIFR FCGR3A SYNE2 AKR1C3	9.21e-07	172	134	7	86f52f486d67217fc1b8443ab362c975df2974a4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 ZAP70 FANCA LIFR FCGR3A SYNE2 AKR1C3	9.21e-07	172	134	7	fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP8B4 ZAP70 FANCA LIFR FCGR3A SYNE2 AKR1C3	9.21e-07	172	134	7	e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KRT5 EPHA6 SPOCK1 KCTD8 PKHD1L1 FNDC1 EPHA5	1.67e-06	188	134	7	9655a4c47b644a870017d349b99063e17dbae572
ToppCell	368C-Myeloid-Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ATP6AP1 DNAAF4 LAMP2 SORT1 LIPA FCGR3A AKR1C3	1.99e-06	193	134	7	c8883731567d0def96e4105dc34b995d1275ddf4
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ATP8B4 KIF1B OLR1 SORT1 SYNE2 SORL1 TMEM63A	2.35e-06	198	134	7	3bc05b8d97a7219af40db7a11aa271f02e74fca5
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	DOCK9 RFTN2 TEX14 PTPRB SYNE2 AKAP11 SORL1	2.35e-06	198	134	7	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|367C / Donor, Lineage, Cell class and subclass (all cells)	TTC16 ZAP70 FCGR3A SYNE2 CLEC2D TRAV13-2	7.30e-06	154	134	6	a39877cdf7b441b5c953f744ed30f1d5acf4ea19
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FANCA PLA2G4C RABGAP1L KCTD16 SYNE2 SORL1	7.86e-06	156	134	6	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FANCA USP38 FAM83G PDE5A AKAP11 HERC1	1.46e-05	174	134	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	KCTD8 RFTN2 PKHD1L1 LIFR PTPRB ADGRL2	1.46e-05	174	134	6	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ATP8B4 FGL2 PTPRB FCGR3A AKR1C3	1.65e-05	105	134	5	8f31edf4183587f5b53941475453c5aa49f10bbd
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP8B4 SH3BP2 FGL2 GUF1 LIPA FCGR3A	1.66e-05	178	134	6	aa9f68a66e292f331faef881bbd0d028f0f2b0c5
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK1 TEC ZAP70 FCGR3A CLEC2D SORL1	1.72e-05	179	134	6	de3ddc1264e43727be50d69b81cc84a3c91812a2
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK1 TEC ZAP70 FCGR3A CLEC2D SORL1	1.72e-05	179	134	6	def981e97e3ff9019910c9af3861ca0d08eb0d0f
ToppCell	Control-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP8B4 TEC ZAP70 FCGR3A CLEC2D SORL1	1.95e-05	183	134	6	2c5707ada3442eb7100a2a5f9438d5a2ac53a9e1
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 DCC TEX11 PKHD1L1 DISP3 EPHA5	2.01e-05	184	134	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 DCC TEX11 PKHD1L1 DISP3 EPHA5	2.01e-05	184	134	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 DCC TEX11 PKHD1L1 DISP3 EPHA5	2.01e-05	184	134	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 SPOCK1 KCTD8 DCC FNDC1 PDE5A	2.07e-05	185	134	6	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT5 SPOCK1 KCTD8 PKHD1L1 FNDC1 EPHA5	2.07e-05	185	134	6	492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TRMT9B EPHA6 MROH5 PKHD1L1 SORL1	2.16e-05	111	134	5	1847dde68d349114286bc3317be6339666df4aa2
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	DOCK9 KCTD8 PKHD1L1 LIFR PTPRB ADGRL2	2.20e-05	187	134	6	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	ZAP70 PACS1 RABGAP1L SYNE2 CLEC2D SORL1	2.20e-05	187	134	6	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRPM6 ATP8B4 KIF1B MBOAT2 OLR1 SORT1	2.33e-05	189	134	6	3b35022c0619df6db234613aa53a076899ca9562
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRPM6 ATP8B4 KIF1B MBOAT2 OLR1 SORT1	2.33e-05	189	134	6	358ff514f1c8aa46067208ddf1b68396d789c130
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRMT9B DOCK9 ITGA2B PKHD1L1 PLA2G4C AKR1C3	2.40e-05	190	134	6	32400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRMT9B DOCK9 ITGA2B PKHD1L1 PLA2G4C AKR1C3	2.40e-05	190	134	6	b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell	Caecum-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	ABL2 LAMP2 OLR1 KIF20B SORT1 AKAP11	2.40e-05	190	134	6	54463f6f1718f22704175bd034f134de3b55d2eb
ToppCell	COVID-19-T_cells-CD4+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	DOCK9 ZAP70 RABGAP1L SYNE2 CLEC2D SORL1	2.47e-05	191	134	6	0646cca78e24aeb6baa9934d3c439b797c567997
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	DOCK9 ZAP70 SYNE2 CLEC2D HERC1 SORL1	2.55e-05	192	134	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 SLC6A17 OLR1 ABCA5 ADGRL2 IGSF3	2.55e-05	192	134	6	46ea8f4f292db70420b378c6fa3e55e99413679c
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRMT9B DOCK9 ITGA2B PKHD1L1 PLA2G4C AKR1C3	2.62e-05	193	134	6	ef007b736da56529ec628fc3df86a335e7ec3f18
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage\|367C / Donor, Lineage, Cell class and subclass (all cells)	ATP6AP1 LAMP2 OLR1 SORT1 LIPA FCGR3A	2.70e-05	194	134	6	40c91ed945bd5990a0dbf2090d37a660b19aaab2
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC44A2 PKHD1L1 FGL2 PTPRB SYNE2 ADGRL2	2.70e-05	194	134	6	660535b492445063d965095a50e1e299ce04c50a
ToppCell	COVID-19-lung-NK_cells\|lung / Disease (COVID-19 only), tissue and cell type	TTC16 ZAP70 RABGAP1L SYNE2 CLEC2D SORL1	2.78e-05	195	134	6	3b716ec7acc9a37af6bf40e711a539ce58d74aa4
ToppCell	COVID_vent-Myeloid-Monocytic-Developing_Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TRPM6 ATP8B4 KIF1B MBOAT2 OLR1 SORT1	2.78e-05	195	134	6	de23409b1b4146b8ae286850b829ec8dceed0117
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 SLC6A17 OLR1 ABCA5 ADGRL2 IGSF3	2.78e-05	195	134	6	60d08fb27469d1e247bc47b651d7023ba82cf92f
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DNAAF4 LAMP2 SORT1 LIPA FCGR3A AKR1C3	2.78e-05	195	134	6	f664fe18856065baaa2837fc82ea946e45f6fcc3
ToppCell	10x5'-Liver-Lymphocytic_NK-NK_CD16\|Liver / Manually curated celltypes from each tissue	SLC44A2 ZAP70 FCGR3A SYNE2 AKR1C3 SORL1	2.86e-05	196	134	6	e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 TMEM67 DNAAF4 ECT2L SYNE2 WDR90	2.94e-05	197	134	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	DOCK9 MBOAT2 LIFR PTPRB SYNE2 ADGRL2	2.94e-05	197	134	6	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	Transplant_Alveoli_and_parenchyma-Immune-Luminal_Macrophages\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ATP6AP1 LAMP2 OLR1 LIPA FCGR3A AKR1C3	2.94e-05	197	134	6	523a7f363c7ba8c196ea6e4f7544c29c18c10b51
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ATP8B4 LAMP2 OLR1 FCGR3A SYNE2 SORL1	3.03e-05	198	134	6	82f6ac18c3a6487f03579b5c247844f1c115c2be
ToppCell	mild_COVID-19_(asymptomatic)-NK\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	ZAP70 FCGR3A SYNE2 AKR1C3 KLHDC4 SORL1	3.03e-05	198	134	6	1e43181c13e054570046c7a973ddc1c586e259b0
ToppCell	(0)_NK_cells-(0)_NK_FCGR3Apos\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ZAP70 FGL2 FCGR3A SYNE2 AKR1C3 SORL1	3.03e-05	198	134	6	eba39656c6f699ab297b652ded8cb9727b49593c
ToppCell	cellseq-Immune-Immune_Myeloid-AM-AM\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ATP6AP1 LAMP2 OLR1 LIPA FCGR3A AKR1C3	3.11e-05	199	134	6	255cf629351f35e516a5271d8758c29168ebd0cf
ToppCell	cellseq-Immune-Immune_Myeloid-AM\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ATP6AP1 LAMP2 OLR1 LIPA FCGR3A AKR1C3	3.11e-05	199	134	6	298302123a2b3815ed98130fa1a229e56e8ab77b
ToppCell	Control-Control-Others-HSPC\|Control / Disease, condition lineage and cell class	ATP8B4 NTRK1 MBOAT2 AKR1C3 CPXM1 TEC	3.11e-05	199	134	6	b71169be0d916b2ed139a3122d78bb154c71edb4
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ATP8B4 OLR1 VNN1 SYNE2 SORL1 TMEM63A	3.11e-05	199	134	6	a1635a52318be0423f8e4fc03d971c28cd22b57e
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ATP8B4 KIF1B LAMP2 SORT1 VNN1 SORL1	3.11e-05	199	134	6	b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MCM7 OLR1 FANCA FCGR3A AKR1C3 UGT2B17	3.11e-05	199	134	6	e1190b1c2d21fed313bb58e24d0e6365de6e6599
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ATP6AP1 LAMP2 OLR1 SORT1 LIPA FCGR3A	3.20e-05	200	134	6	980cb0390586d8312890e8d0f3cf58e3309d16c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TRIO DOCK9 LIFR PTPRB SYNE2 ADGRL2	3.20e-05	200	134	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Lung_Parenchyma-Control-Myeloid-TRAM\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATP6AP1 LAMP2 OLR1 LIPA FCGR3A AKR1C3	3.20e-05	200	134	6	ecd2b9a7d464792b77381d0a0bc7030e77ad3581
ToppCell	Lung_Parenchyma-Control-Myeloid-TRAM-TRAM\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATP6AP1 LAMP2 OLR1 LIPA FCGR3A AKR1C3	3.20e-05	200	134	6	b303553aca8fc021f932b52e88e9ef270d5a4f03
ToppCell	Lung_Parenchyma-Control-Myeloid-TRAM-TRAM-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATP6AP1 LAMP2 OLR1 LIPA FCGR3A AKR1C3	3.20e-05	200	134	6	ec39df7fb4454af629a4a4f6755bd02c9581a2ca
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ATP6AP1 LAMP2 OLR1 SORT1 LIPA FCGR3A	3.20e-05	200	134	6	d7d971586c01152b3d21956fd98280588cb8f08b
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ATP6AP1 LAMP2 OLR1 FGL2 LIPA FCGR3A	3.20e-05	200	134	6	bbe9597f8656f9652ba0c810fd962eaa434b3200
ToppCell	Parenchyma_Control_(B.)-Immune-TX-TRAM-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ATP6AP1 LAMP2 OLR1 LIPA FCGR3A AKR1C3	3.20e-05	200	134	6	b92804f15586e1802fdd931d6dfe742be8466944
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MROH5 MST1R KCNQ4 CLRN1	4.16e-05	64	134	4	0f13fbeda23ab9df3488cfae98cb6cd7a3c1b332
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MROH5 MST1R KCNQ4 CLRN1	5.60e-05	69	134	4	3074ec10315fb21048215125ec08b0d7922da3d9
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MROH5 MST1R KCNQ4 CLRN1	5.60e-05	69	134	4	f731d4500b139a8bef5c9185368509bf5a3791db
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MROH5 MST1R KCNQ4 CLRN1	5.60e-05	69	134	4	40eb84fe36da5a4a82bd9b2d962b829e2c97a059
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 PNLIP KCTD8 ABCA5 ADGRL2	7.03e-05	142	134	5	5b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY10 DOCK3 EPHA6 ABCC2 EPHA5	7.76e-05	145	134	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	KIF21B ZAP70 SYNE2 CLEC2D TRAV13-2	8.27e-05	147	134	5	743767abdb3b5ecad870b617f515b037ce280818
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_C\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FGL2 FCGR3A KCTD16 SYNE2 AKR1C3	8.82e-05	149	134	5	95b21d67d6c335330a508f78d5cc074fdaf92275
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRPM6 ENPP1 BLMH CLRN1 SORL1	9.69e-05	152	134	5	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 MAP6 ALMS1 ABCA5 TMEM63A	1.06e-04	155	134	5	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM7 TEC PLA2G4C FAM83G SERPINC1	1.09e-04	156	134	5	6f8622716bad4e505f241a2a4ef953bf3fc6dbfa
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	TTC16 ENPP1 ZAP70 SYNE2 CLEC2D	1.09e-04	156	134	5	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Mgp)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	APOA5 ZAP70 KIF20B FAM83G	1.15e-04	83	134	4	21d4b74b48a4377e81f1e00bba9c654f2a0d714b
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Mgp)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	APOA5 ZAP70 KIF20B FAM83G	1.15e-04	83	134	4	148171cf2cd253e502185848512b7c17096d701f
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Mgp)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	APOA5 ZAP70 KIF20B FAM83G	1.15e-04	83	134	4	fd7fd3d781b096dea51a5e5d5f516699f6e7bd57
ToppCell	COVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TRPM6 NTRK1 ITGA2B TNN CPXM1	1.16e-04	158	134	5	0d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ABL2 FGL2 SLC13A4 CPXM1 TEC	1.20e-04	159	134	5	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_D\|356C / Donor, Lineage, Cell class and subclass (all cells)	TTC16 ZAP70 FCGR3A SYNE2 AKR1C3	1.27e-04	161	134	5	8fe9fde47e691c443d13d8616c654fbae2d5675c
ToppCell	severe_influenza-cDC\|World / disease group, cell group and cell class (v2)	MAP6 ENPP1 KCNQ4 EPHA2 KCTD16	1.27e-04	161	134	5	802f8cafb5f499e3b2ec0193d6eb1ac9320b9287
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIGN SYNRG WDR55 IGSF3 SORL1	1.27e-04	161	134	5	9f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCell	severe_influenza-cDC\|severe_influenza / disease group, cell group and cell class (v2)	MAP6 ENPP1 KCNQ4 EPHA2 KCTD16	1.27e-04	161	134	5	7716315b8bda904b346cea47edc2c0b507a345c2
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SH3BP2 OLR1 LIPA FCGR3A KLHDC4	1.31e-04	162	134	5	16d625ac6702f79a83af444d2b3bf6759fd17cf6
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|367C / Donor, Lineage, Cell class and subclass (all cells)	TTC16 ZAP70 FCGR3A KCTD16 SYNE2	1.38e-04	164	134	5	4a834a7908d8aa643a2096c52430dad795898474
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 SLC6A17 ITGA2B OLR1 POLR3F	1.42e-04	165	134	5	50f1fa7434ebb777e15d5273d1ff41070cff6db3
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 SH3BP2 OLR1 KIF20B KLHDC4	1.42e-04	165	134	5	1dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 LIFR PTPRB MANSC4 GRAMD1C	1.51e-04	167	134	5	774f3264318b002d0df5d06d41d645366038d0bf
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B SH3BP2 MST1R FNDC1 ALMS1	1.51e-04	167	134	5	f5bffa77061baec0ba87bd688a047595f32534db
ToppCell	facs-Aorta-Heart-24m-Endothelial-endocardial_endothelial_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B EPHA6 OLR1 FGL2 RARS2	1.55e-04	168	134	5	edbab94f14e16a1a76546a18fe777a183080d1de
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAAF4 ZAP70 KIF20B FGL2 WDR90	1.55e-04	168	134	5	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF21B ATP8B4 TEC KIF20B FANCA	1.68e-04	171	134	5	6e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|390C / Donor, Lineage, Cell class and subclass (all cells)	TTC16 ZAP70 FCGR3A SYNE2 CLEC2D	1.68e-04	171	134	5	d6d8ea45b443d95f64720c9bc07d324148f5b239
ToppCell	droplet-Liver\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOA5 LAMP2 F2 LIPA SERPINC1	1.73e-04	172	134	5	cd0e8f48836a16026b47ade06abadf26b53f581f
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 SH3BP2 OLR1 FCGR3A KLHDC4	1.73e-04	172	134	5	584af6537685cb459bf0fc298e6f46872016c116
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 ITGA2B TEC FCGR3A HERC1	1.73e-04	172	134	5	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	3'_v3-blood-Mast\|blood / Manually curated celltypes from each tissue	TRPM6 TRIO NTRK1 ITGA2B MBOAT2	1.73e-04	172	134	5	e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 ITGA2B TEC FCGR3A HERC1	1.73e-04	172	134	5	953b05f776348cff784e79c93df65841939d880f
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 SH3BP2 OLR1 FCGR3A KLHDC4	1.77e-04	173	134	5	279efbab7810fa60ab12ea5d09a84800df4adef0
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK1 TEC ZAP70 FCGR3A CLEC2D	1.77e-04	173	134	5	fde1fabb8d13d05998ac3f21ecb1fde6a7a2f337
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 TRMT9B OLR1 ABCA5 IGSF3	1.77e-04	173	134	5	0c74bdb40e635d906fd180412c23bf7fed61621e
Drug	T-NK	ITGA2B F2 ZAP70 FGL2 SERPINC1	1.71e-06	35	132	5	CID000446515
Drug	elarofiban	ITGA2B F2 FGL2	3.76e-06	6	132	3	CID000216230
Drug	clobazam	F2 SERPINC1 ABCC2	1.04e-05	8	132	3	ctd:C012255
Drug	F XV	ITGA2B F2 SERPINC1	1.56e-05	9	132	3	CID004631609
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A	SYNRG SORT1 ALMS1 SYNE2 UBA6 AKAP11 HERC1 SORL1	1.61e-05	191	132	8	4168_DN
Drug	Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	NTRK1 DOCK9 WDR55 EXTL3 FANCA SORT1 ABCC2 TMEM63A	2.08e-05	198	132	8	3415_UP
Drug	Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A	TRMT9B TRIO ENPP1 FGL2 LIFR RABGAP1L KCNS1 TMEM63A	2.16e-05	199	132	8	3603_UP
Drug	phenolphthalein glucuronide	UGT2B15 ABCC2	3.34e-05	2	132	2	ctd:C016651
Drug	Bz-leu-ala-arg-ne	F2 SERPINC1	3.34e-05	2	132	2	CID000133691
Drug	Ioxaglic Acid	F2 SERPINC1	3.34e-05	2	132	2	ctd:D007485
Drug	P 8714	F2 SERPINC1	3.34e-05	2	132	2	CID000130138
Drug	Rgh 2958	F2 FGL2 SERPINC1	4.03e-05	12	132	3	CID000124710
Drug	C12063	PIGN ATP6AP1 LAMP2 F2 FGL2 SORT1 PTPRB PRKCSH EXOC2 ADGRL2 SORL1	4.20e-05	429	132	11	CID005282055
Drug	triethylene glycol	ITGA2B F2 FGL2 SORT1 SERPINC1	4.39e-05	67	132	5	CID000008172
Disease	DNA repair protein RAD51 homolog 4 measurement	TEX14 UGT2B15 UGT2B17	1.41e-05	11	132	3	EFO_0801531
Disease	metabolite measurement	ATP8B4 SPOCK1 DCC ALMS1 SYNE2 AKR1C3 UGT2B15 UGT2B17 ABCC2 TMEM258 SORL1	4.56e-05	560	132	11	EFO_0004725
Disease	cholic acid glucuronide measurement	UGT2B15 UGT2B17	5.94e-05	3	132	2	EFO_0800574
Disease	cystathionine measurement	TEC AKR1C3 TEC	8.05e-05	19	132	3	EFO_0010474
Disease	colorectal cancer, inflammatory bowel disease	ATP8B4 ALMS1 KCNQ4	8.05e-05	19	132	3	EFO_0003767, MONDO_0005575
Disease	Sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1) measurement	SYNE2 TMEM258	1.18e-04	4	132	2	EFO_0022112
Disease	X-25937 measurement	UGT2B15 UGT2B17	1.18e-04	4	132	2	EFO_0800937
Disease	hereditary multiple exostoses (implicated_via_orthology)	EXTL1 EXTL3	1.18e-04	4	132	2	DOID:206 (implicated_via_orthology)
Disease	lysophosphatidylcholine 22:1 measurement	MBOAT2 TMEM258	1.18e-04	4	132	2	EFO_0021460
Disease	tyrosine-protein kinase TEC measurement	TEC TEC	1.18e-04	4	132	2	EFO_0020830
Disease	Cholestasis	SORT1 LIPA DGUOK ABCC2 SORL1	1.40e-04	110	132	5	C0008370
Disease	HDL cholesterol change measurement	APOA5 MBOAT2 SYNE2	1.65e-04	24	132	3	EFO_0007805
Disease	diacylglycerol 44:6 measurement	APOA5 SYNE2	1.97e-04	5	132	2	EFO_0020070
Disease	Coronary Arteriosclerosis	APOA5 ZC3HC1 SORT1 LIPA	2.10e-04	65	132	4	C0010054
Disease	Coronary Artery Disease	APOA5 ZC3HC1 SORT1 LIPA	2.10e-04	65	132	4	C1956346
Disease	cortolone glucuronide (1) measurement	AKR1C3 UGT2B15	2.94e-04	6	132	2	EFO_0800552
Disease	disseminated intravascular coagulation (implicated_via_orthology)	F2 SERPINC1	2.94e-04	6	132	2	DOID:11247 (implicated_via_orthology)
Disease	birth measurement, spontaneous preterm birth	ADGRL2 SORL1	4.11e-04	7	132	2	EFO_0006917, EFO_0006921
Disease	Disseminated Intravascular Coagulation	F2 SERPINC1	4.11e-04	7	132	2	C0012739
Disease	X-24574 measurement	UGT2B15 UGT2B17	4.11e-04	7	132	2	EFO_0800897
Disease	androsterone sulfate measurement	DCC UGT2B15 UGT2B17	4.33e-04	33	132	3	EFO_0021117
Disease	Thrombophilia due to thrombin defect	F2 SERPINC1	5.46e-04	8	132	2	cv:C3160733
Disease	deoxycholic acid glucuronide measurement	UGT2B15 UGT2B17	5.46e-04	8	132	2	EFO_0800575
Disease	Venous Thromboembolism	F2 SERPINC1	5.46e-04	8	132	2	C1861172
Disease	cholestasis (implicated_via_orthology)	LAMP2 ABCC2	7.00e-04	9	132	2	DOID:13580 (implicated_via_orthology)
Disease	4-androsten-3alpha,17alpha-diol monosulfate (3) measurement	UGT2B15 UGT2B17	8.73e-04	10	132	2	EFO_0022090
Disease	thrombosis (implicated_via_orthology)	F2 SERPINC1	8.73e-04	10	132	2	DOID:0060903 (implicated_via_orthology)
Disease	venous thromboembolism, von Willebrand factor measurement	SLC44A2 F2 TMEM258	8.84e-04	42	132	3	EFO_0004286, EFO_0004629
Disease	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	TEC FCGR3A EXOC2 TMEM258 TEC	1.03e-03	170	132	5	EFO_0000685, EFO_0007791, EFO_0007837
Disease	glomerulonephritis (is_implicated_in)	F2 FCGR3A	1.06e-03	11	132	2	DOID:2921 (is_implicated_in)
Disease	coronary artery disease (is_implicated_in)	APOA5 F2 OLR1 FCGR3A	1.08e-03	100	132	4	DOID:3393 (is_implicated_in)
Disease	serum metabolite measurement	EPHA6 TRIO APOA5 MROH1 ALMS1 RABGAP1L SYNE2 AKR1C3 UGT2B15 PRKCSH ABCC2 TMEM258	1.13e-03	945	132	12	EFO_0005653
Disease	N-delta-acetylornithine measurement	ALMS1 DGUOK	1.27e-03	12	132	2	EFO_0800067
Disease	5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement	UGT2B15 UGT2B17	1.27e-03	12	132	2	EFO_0800291
Disease	cholesteryl ester 20:3 measurement	TRMT9B APOA5 TMEM258	1.39e-03	49	132	3	EFO_0010347
Disease	omega-6:omega-3 polyunsaturated fatty acid ratio	UGT2B15 UGT2B17 TMEM258	1.47e-03	50	132	3	EFO_0010732
Disease	Bardet-Biedl Syndrome	TMEM67 ALMS1	1.50e-03	13	132	2	C0752166
Disease	androstenediol (3alpha, 17alpha) monosulfate (3) measurement	UGT2B15 UGT2B17	1.50e-03	13	132	2	EFO_0800293
Disease	X-19141 measurement	UGT2B15 UGT2B17	1.50e-03	13	132	2	EFO_0800799
Disease	5alpha-androstan-3alpha,17alpha-diol monosulfate measurement	UGT2B15 UGT2B17	1.74e-03	14	132	2	EFO_0800283
Disease	Acute Cerebrovascular Accidents	ITGA2B PRPF8 F2	1.84e-03	54	132	3	C0751956
Disease	omega-3 polyunsaturated fatty acid measurement	APOA5 UGT2B15 UGT2B17 TMEM258	1.98e-03	118	132	4	EFO_0010119
Disease	N-acetylmethionine measurement	DOCK3 ALMS1	2.01e-03	15	132	2	EFO_0021427
Disease	thrombosis (is_implicated_in)	F2 SERPINC1	2.01e-03	15	132	2	DOID:0060903 (is_implicated_in)
Disease	diacylglycerol 36:2 measurement	APOA5 TMEM258	2.29e-03	16	132	2	EFO_0010355
Disease	Blood Coagulation Disorders	F2 SERPINC1	2.29e-03	16	132	2	C0005779
Disease	Liver Cirrhosis, Experimental	SYNRG SLC44A2 EXTL1 ITGA2B FGL2 FCGR3A RABGAP1L AKR1C3 APPL1 ABCC2	2.58e-03	774	132	10	C0023893
Disease	Ischemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism	SLC44A2 F2	2.58e-03	17	132	2	EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Disease	Cerebrovascular accident	ITGA2B PRPF8 F2	2.73e-03	62	132	3	C0038454
Disease	diacylglycerol 36:3 measurement	APOA5 TMEM258	2.90e-03	18	132	2	EFO_0020062
Disease	5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement	UGT2B15 UGT2B17	2.90e-03	18	132	2	EFO_0800288
Disease	blood metabolite measurement	ALMS1 EXOC2	3.23e-03	19	132	2	EFO_0005664
Disease	etiocholanolone glucuronide measurement	UGT2B15 UGT2B17	3.23e-03	19	132	2	EFO_0800362
Disease	end stage renal disease (implicated_via_orthology)	F2 ABCC2	3.58e-03	20	132	2	DOID:783 (implicated_via_orthology)
Disease	freckles	FANCA EXOC2	3.58e-03	20	132	2	EFO_0003963
Disease	androsterone glucuronide measurement	UGT2B15 UGT2B17	3.58e-03	20	132	2	EFO_0800317
Disease	neutrophil count	FOXJ2 NTRK1 SLC6A17 KIF1B ZC3HC1 TEX14 FANCA MST1R LIPA RABGAP1L AKAP11 ADGRL2 TMEM258 USP47	3.63e-03	1382	132	14	EFO_0004833
Disease	skin pigmentation	ATP8B4 FANCA EXOC2	3.70e-03	69	132	3	EFO_0003784
Disease	alcohol consumption measurement	PIGN DCC MBOAT2 MST1R PTPRB PLA2G4C ALMS1 RABGAP1L AKAP11 WDR90 SETD3 ADGRL2 SORL1	3.84e-03	1242	132	13	EFO_0007878
Disease	Deep Vein Thrombosis	F2 SERPINC1	3.94e-03	21	132	2	C0149871
Disease	Venous Thrombosis	F2 SERPINC1	3.94e-03	21	132	2	C0042487
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	DCC TMEM258	3.94e-03	21	132	2	OBA_2045104
Disease	metabolite measurement, diet measurement	APOA5 MST1R TMEM258	4.01e-03	71	132	3	EFO_0004725, EFO_0008111
Disease	X-24947 measurement	UGT2B15 UGT2B17	4.33e-03	22	132	2	EFO_0800910
Disease	nucleotide measurement	ATP8B4 PTPRB SYNE2	4.33e-03	73	132	3	EFO_0010513

Protein segments in the cluster

Peptide	Gene	Start	Entry
LNTKEFWSFIYSVAA	ABCA5	1131	Q8WWZ7
YTWFNSEYQVRKSSE	ADAM5	126	Q6NVV9
SFWISSSTYKDRNEE	GRAMD1C	56	Q8IYS0
KSSFQTYSDYLRWES	DISP3	1131	Q9P2K9
SLAYNTFSIKSDVWA	ABL2	456	P42684
REDIFYTSKLWSTFH	AKR1C3	76	P42330
SFSSENYWRKSYESS	ALKBH5	361	Q6P6C2
AFRKFTSASDVWSYG	EPHA5	851	P54756
RTWFFSASSEEERKS	SH3BP2	106	P78314
ARSYGQYWTQEDSSK	ALMS1	391	Q8TCU4
VTSYKVQFSNDSRTW	CPXM1	201	Q96SM3
WSYTFQTFSFLSRLK	DGUOK	106	Q16854
TWETVYDKRAASNAF	ADGRL2	301	O95490
WTQRSFYRSSNASDK	AKAP11	276	Q9UKA4
SAFSATQARKGFWDY	APOA5	16	Q6Q788
TQARKGFWDYFSQTS	APOA5	21	Q6Q788
SIYFCESKLQTWSSF	ECT2L	446	Q008S8
EKSSVFSGFLTFWSY	ATP8B4	316	Q8TF62
DKSWSQTFESATFYS	ADCY10	1121	Q96PN6
WELSKANSRFATTFY	SERPINC1	81	P01008
YDITNTDTFARAKNW	RAB5C	101	P51148
YTVFNAFDDDSTSWA	RFTN2	246	Q52LD8
ESWATDRLYSSAEFK	GUF1	41	Q8N442
FFKYNATTDQWSELV	KBTBD3	476	Q8NAB2
KSLRSYWRNYFESTD	ARL2	71	P36404
YAVWATSRSFAAFLA	MFSD10	131	Q14728
FYSLTSSNISKWELD	NUP133	286	Q8WUM0
YTVRWRTSFSASAKY	DCC	881	P43146
YRKFTTESDVWSFGV	NTRK1	701	P04629
ESTSWNEYTFFNLTA	PTPRB	161	P23467
SWFSDTNGAVKYFTV	PTPRB	1476	P23467
FVNQYRDDKIWSSYT	KCTD8	301	Q6ZWB6
AVSSSYRNEFRAWTD	MAP6	296	Q96JE9
IWAYFDKEFSITEFS	MAIP1	131	Q8WWC4
WFRTYLHSSKTSSFI	MBOAT2	41	Q6ZWT7
ASFINQYTDDKIWSS	KCTD16	256	Q68DU8
QSKEFREYVSSTHFW	MPC1L	16	P0DKB6
YSSATSEWRLSYVNK	MTMR9	136	Q96QG7
TGDASNFARWRYKVS	PNLIP	346	P16233
TQTDATSFYDRVWAA	PRKCSH	261	P14314
SRTFYRFEAVWDSSL	KIF1B	1351	O60333
NRSRTEAESWYQTKY	KRT5	351	P13647
GLVSSTWDRQFYFTQ	APPL1	291	Q9UKG1
RDWLCNSSYSFESDF	HERC1	1566	Q15751
KDANSDFSSYADSLW	KCNQ4	261	P56696
SSFQSGRDDTWRYKT	EXOC2	431	Q96KP1
DHWDFTFSYFVRKAT	PDE5A	36	O76074
KAFTYDFVFDLDTWQ	KIF21B	46	O75037
SIKFSVWVSFFEIYN	KIF20B	266	Q96Q89
YSKELTTDFWARFTS	MANSC4	191	A6NHS7
FSWIANFTKAASTYS	LAMP2	96	P13473
EYSCFSFRKLWAFTG	SLC11A2	61	P49281
EYFCIAWFSFEVSSR	KCNS1	276	Q96KK3
SAWTSDSKIFNSTDY	ABCC2	1001	Q92887
LWTSYTVDRNDSFST	ENPP1	691	P22413
FSYSEINFQDLSWSF	FOXJ2	241	Q9P0K8
DFFFRWLFDKTSSEA	TMEM63A	526	O94886
TCLFYFKSSWENVRA	MROH1	1571	Q8NDA8
YLFSSGSFNWEKSQE	OLR1	156	P78380
EAWASKDATYTSART	MCM7	591	P33993
VDSKYSSSFLDSGWR	PACS1	676	Q6VY07
ERFWYFSRKTFTETF	RABGAP1L	421	Q5R372
AWSDTYDTFKLADTY	PLA2G4C	481	Q9UP65
DRYFAVSWAFNSSLI	IGSF3	311	O75054
SQDSRFAVAWYSLRT	IGSF3	981	O75054
TDFDFKVWNSYFSLA	DOCK3	1026	Q8IZD9
DDALFTYWNKASTSE	DOCK9	1316	Q9BZ29
SYEDFIRNKWSTQAS	FNDC1	1696	Q4ZHG4
YRKFTSASDVWSFGI	EPHA2	791	P29317
QGRFLWETYFSTADS	EXTL3	511	O43909
WETYFSTADSIFNTV	EXTL3	516	O43909
LSYADWFKASFGSTR	FANCA	446	O15360
EFSQSYLFFWDKVER	BLMH	96	Q13867
SDYSWQQTKTAVFLS	DNAAF4	6	Q8WXU2
STNFTRTWQDYKAGF	FGL2	261	Q14314
NDVYAFNLDTFTWSK	KLHDC4	206	Q8TBB5
AYWASTAVFLSTSNE	SLC44A2	376	Q8IWA5
YFSVKTNIRSSTRDW	FCGR3A	226	P08637
WDSFFEKKGYRTDAT	SLC13A4	401	Q9UKG4
YFFEKVVNAAQTWFS	CFAP47	1531	Q6ZTR5
LWAYTSSHDDKSTFE	C18orf21	26	Q32NC0
ADFSTSTLYLKWNDR	LIFR	146	P42702
EAIAYRKFSSASDAW	EPHA6	846	Q9UF33
LTSEWFAKYLQSSAA	TMEM67	221	Q5HYA8
YSSWDETLKQSFLTA	MROH5	411	Q6ZUA9
WRSSESKPEFFYSEE	FAM83G	16	A6ND36
LLSDYKFSWDRVFQS	RARS2	441	Q5T160
SFLTSQWVSYTIDFK	SORT1	591	Q99523
DDWSQLSIFRASKYS	SORL1	976	Q92673
SLWATSREFTNAYKL	TEX14	776	Q8IWB6
ATYESVNVTDFKSSW	SYNE2	196	Q8WXH0
FAVSTLTSYDWSDRD	SYNRG	886	Q9UMZ2
VFNYSRFSSKSDVWS	TEC	536	P42680
SFKAQWQETTYNLFT	GNRHR2	106	Q96P88
QKIYRSDFWNFSSLD	SLITRK3	421	O94933
KDSFTYEDYRWAVSS	SETD3	236	Q86TU7
SFEAFFQSKASNSWT	ST6GALNAC2	46	Q9UJ37
TASFRTSKYLLEEWF	TEKT4	31	Q8WW24
RNSSFASSHEVWKYI	POLR3F	206	Q9H1D9
FSWDKRYCEAGFSSV	ITGA2B	191	P08514
QTQFLWDAYFSSVEK	EXTL1	346	Q92935
CKDEDFSTSSVWRSY	SETDB1	911	Q15047
RDKCFYFSDDTRNWT	CLEC2A	66	Q6UVW9
YFSDDTRNWTASKIF	CLEC2A	71	Q6UVW9
CFYFSDDTKNWTSSQ	CLEC2D	86	Q9UHP7
QSEKYTTSFWVIFFC	CLRN1	181	P58418
DDWLKTISSYTAFSR	PRPF8	1921	Q6P2Q9
EAFFSRVETFSSLKW	ZC3HC1	76	Q86WB0
FNKFWQTYSSAEEVL	UBA6	656	A0AVT1
KTSAATDVWAVYFSQ	UHRF1BP1L	686	A0JNW5
DSAQSFITSSWTFYL	TMEM59	156	Q9BXS4
FITSSWTFYLQADDG	TMEM59	161	Q9BXS4
INFRKFSSRSDVWSY	ZAP70	511	P43403
SFSNLFKEFKSTATW	WDR90	101	Q96KV7
FGRLYEKDWASNASS	VNN1	476	O95497
EYSKNWFTVSKFSHT	TRPM6	1621	Q9BX84
ALTYHNGWKFTTFDR	TNN	1201	Q9UQP3
ACIKSFSDEQWYSFN	USP47	506	Q96K76
STVSQYDRDKYWNRF	SPOCK1	46	Q08629
NKYEESSFWLSQSYD	TEX11	236	Q8IYF3
IKTTSFSDYYQTWSR	UBE2U	171	Q5VVX9
FSDYYQTWSRIATSK	UBE2U	176	Q5VVX9
FWNDSFARLSLTYER	ATP6AP1	301	Q15904
NADFLYVDAWSSNFS	PKHD1L1	2171	Q86WI1
ALTAAVFVATDSWYF	PIGZ	266	Q86VD9
VEFDSLFNESKYTWS	PIGN	121	O95427
KEWFLFNDSRVTFTS	USP38	911	Q8NB14
GTRAKTSAVWNFFYT	ZBED6	261	P86452
RALSSKTWSTDDFFA	WDR55	346	Q9H6Y2
EEYSDTLSNFESFKW	ZGRF1	636	Q86YA3
TLSNFESFKWTDAVY	ZGRF1	641	Q86YA3
SFRSWFFSRSLDEST	TRMT9B	246	Q9P272
SSTATDVFWAKYTAC	F2	76	P00734
CEKSSATTYFWYREA	SLC6A17	196	Q9H1V8
SSTKTEAFYDSNWSL	TTC16	801	Q8NEE8
EAFYDSNWSLSKTEY	TTC16	806	Q8NEE8
FFTAWFFVYEVTSTK	TMEM258	31	P61165
VSKNTFWSYFSQLQE	UGT2B15	101	P54855
TYRFTTKSDVWSFGV	MST1R	1261	Q04912
ISKNTFWSYFSQLQE	UGT2B17	101	O75795
VTWKDNFDSFYSEVA	TRIO	2786	O75962
SNSASDYFIWYKQES	TRAV13-2	46	A0A0B4J235
TLSVSQDEFWAFSYD	LIPA	131	P38571