Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endopolyphosphatase activity	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	2.08e-12	5	94	5	GO:0000298
GeneOntologyMolecularFunction	bis(5'-adenosyl)-hexaphosphatase activity	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	2.08e-12	5	94	5	GO:0034431
GeneOntologyMolecularFunction	diphosphoinositol-polyphosphate diphosphatase activity	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	2.08e-12	5	94	5	GO:0008486
GeneOntologyMolecularFunction	bis(5'-adenosyl)-pentaphosphatase activity	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.24e-11	6	94	5	GO:0034432
GeneOntologyMolecularFunction	inositol bisdiphosphate tetrakisphosphate diphosphatase activity	NUDT4 NUDT3	2.19e-05	2	94	2	GO:0052841
GeneOntologyMolecularFunction	inositol diphosphate pentakisphosphate diphosphatase activity	NUDT4 NUDT3	2.19e-05	2	94	2	GO:0052842
GeneOntologyMolecularFunction	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	NUDT4 NUDT3	2.19e-05	2	94	2	GO:0052848
GeneOntologyMolecularFunction	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity	NUDT4 NUDT3	2.19e-05	2	94	2	GO:0052845
GeneOntologyMolecularFunction	soluble NSF attachment protein activity	NAPB NAPA	6.56e-05	3	94	2	GO:0005483
GeneOntologyMolecularFunction	acyl-L-homoserine-lactone lactonohydrolase activity	PON1 PON2	6.56e-05	3	94	2	GO:0102007
GeneOntologyMolecularFunction	lactonohydrolase activity	PON1 PON2	6.56e-05	3	94	2	GO:0046573
GeneOntologyMolecularFunction	neuroligin family protein binding	NRXN1 NRXN2	2.17e-04	5	94	2	GO:0097109
GeneOntologyMolecularFunction	arylesterase activity	PON1 PON2	3.25e-04	6	94	2	GO:0004064
GeneOntologyMolecularFunction	cAMP-dependent protein kinase activity	PRKX PRKY	4.53e-04	7	94	2	GO:0004691
GeneOntologyMolecularFunction	copper ion transmembrane transporter activity	SLC11A2 ATP7B	6.03e-04	8	94	2	GO:0005375
GeneOntologyMolecularFunction	cyclic nucleotide-dependent protein kinase activity	PRKX PRKY	7.73e-04	9	94	2	GO:0004690
GeneOntologyMolecularFunction	5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity	NUDT4 NUDT3	1.17e-03	11	94	2	GO:0140933
GeneOntologyMolecularFunction	MAP-kinase scaffold activity	MAPK8IP1 MAPK8IP2	1.65e-03	13	94	2	GO:0005078
GeneOntologyMolecularFunction	pyrophosphatase activity	NUDT11 NUDT4 ATP7B NUDT3 DHX37 NUDT10 RNF213 MCM4 SLFN11 NUDT4B DNAH8	1.94e-03	839	94	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	NUDT11 NUDT4 ATP7B NUDT3 DHX37 NUDT10 RNF213 MCM4 SLFN11 NUDT4B DNAH8	1.96e-03	840	94	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	NUDT11 NUDT4 ATP7B NUDT3 DHX37 NUDT10 RNF213 MCM4 SLFN11 NUDT4B DNAH8	1.96e-03	840	94	11	GO:0016818
GeneOntologyMolecularFunction	ATP-dependent activity	ATP7B IPO8 MYO9A DHX37 MYO1H RNF213 MCM4 SLFN11 DNAH8	2.42e-03	614	94	9	GO:0140657
GeneOntologyBiologicalProcess	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.77e-12	5	94	5	GO:1901910
GeneOntologyBiologicalProcess	adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.77e-12	5	94	5	GO:1901911
GeneOntologyBiologicalProcess	diadenosine pentaphosphate catabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.77e-12	5	94	5	GO:1901907
GeneOntologyBiologicalProcess	diadenosine pentaphosphate metabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.77e-12	5	94	5	GO:1901906
GeneOntologyBiologicalProcess	diadenosine hexaphosphate catabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.77e-12	5	94	5	GO:1901909
GeneOntologyBiologicalProcess	diadenosine hexaphosphate metabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.77e-12	5	94	5	GO:1901908
GeneOntologyBiologicalProcess	diphosphoinositol polyphosphate metabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.77e-12	5	94	5	GO:0071543
GeneOntologyBiologicalProcess	diadenosine polyphosphate catabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	1.06e-11	6	94	5	GO:0015961
GeneOntologyBiologicalProcess	diadenosine polyphosphate metabolic process	NUDT11 NUDT4 NUDT3 NUDT10 NUDT4B	2.19e-10	9	94	5	GO:0015959
GeneOntologyBiologicalProcess	inositol phosphate metabolic process	NUDT11 NUDT4 NUDT3 INPP5B NUDT10 NUDT4B	1.31e-07	52	94	6	GO:0043647
GeneOntologyBiologicalProcess	polyol metabolic process	NUDT11 NUDT4 NUDT3 INPP5B NUDT10 NUDT4B	2.11e-05	123	94	6	GO:0019751
GeneOntologyBiologicalProcess	SNARE complex disassembly	NAPB NAPA	6.15e-05	3	94	2	GO:0035494
GeneOntologyBiologicalProcess	lactone catabolic process	PON1 PON2	6.15e-05	3	94	2	GO:1901335
GeneOntologyBiologicalProcess	alcohol metabolic process	TTC39B NUDT11 NUDT4 NUDT3 INPP5B NUDT10 PON1 NUDT4B AWAT2	1.10e-04	412	94	9	GO:0006066
GeneOntologyBiologicalProcess	neuroligin clustering involved in postsynaptic membrane assembly	NRXN1 NRXN2	1.23e-04	4	94	2	GO:0097118
GeneOntologyBiologicalProcess	gephyrin clustering involved in postsynaptic density assembly	NRXN1 NRXN2	2.04e-04	5	94	2	GO:0097116
GeneOntologyBiologicalProcess	neuron projection fasciculation	PTPRZ1 CASP6 SEMA5A	2.76e-04	28	94	3	GO:0106030
GeneOntologyBiologicalProcess	axonal fasciculation	PTPRZ1 CASP6 SEMA5A	2.76e-04	28	94	3	GO:0007413
GeneOntologyBiologicalProcess	organophosphate catabolic process	NUDT11 NUDT4 NUDT3 NUDT10 PON1 NUDT4B ABHD12	3.01e-04	281	94	7	GO:0046434
GeneOntologyBiologicalProcess	postsynaptic specialization organization	NRXN1 NRXN2 MYO9A DOCK7	3.11e-04	71	94	4	GO:0099084
GeneOntologyBiologicalProcess	regulation of signaling receptor activity	NRXN1 NRXN2 PPARG PHLDA2 MAPK8IP2	3.34e-04	131	94	5	GO:0010469
GeneOntologyBiologicalProcess	synaptic transmission, glutamatergic	NRXN1 NAPB NAPA GRIA3 MAPK8IP2	3.46e-04	132	94	5	GO:0035249
GeneOntologyBiologicalProcess	neuromuscular process controlling balance	HEXA ABR NRXN1 PTPRQ	3.65e-04	74	94	4	GO:0050885
GeneOntologyBiologicalProcess	cilium movement involved in cell motility	FSIP2 PFN4 SLC9C1 CATSPERE INPP5B DNAH8	4.01e-04	210	94	6	GO:0060294
GeneOntologyBiologicalProcess	vocal learning	NRXN1 NRXN2	4.25e-04	7	94	2	GO:0042297
GeneOntologyBiologicalProcess	imitative learning	NRXN1 NRXN2	4.25e-04	7	94	2	GO:0098596
GeneOntologyBiologicalProcess	cilium-dependent cell motility	FSIP2 PFN4 SLC9C1 CATSPERE INPP5B DNAH8	4.54e-04	215	94	6	GO:0060285
GeneOntologyBiologicalProcess	cilium or flagellum-dependent cell motility	FSIP2 PFN4 SLC9C1 CATSPERE INPP5B DNAH8	4.54e-04	215	94	6	GO:0001539
GeneOntologyBiologicalProcess	maintenance of location	HEXA TTC39B IBTK PFN4 ATP7B PKD2 RNF213 PPARG	4.54e-04	396	94	8	GO:0051235
GeneOntologyBiologicalProcess	regulation of pro-B cell differentiation	SOS1 SOS2	5.65e-04	8	94	2	GO:2000973
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SLC25A46 HEXA SLC11A2 NRXN1 SEMA5B PTPRZ1 PTPRQ DOCK7 SEMA5A MAPK8IP2 SOS1	5.93e-04	748	94	11	GO:0048667
GeneOntologyBiologicalProcess	response to auditory stimulus	NRXN1 NRXN2 ABHD12	6.37e-04	37	94	3	GO:0010996
GeneOntologyBiologicalProcess	observational learning	NRXN1 NRXN2	7.25e-04	9	94	2	GO:0098597
GeneOntologyBiologicalProcess	copper ion transmembrane transport	SLC11A2 ATP7B	7.25e-04	9	94	2	GO:0035434
GeneOntologyCellularComponent	presynaptic active zone membrane	NRXN1 NRXN2 NAPB NAPA GRIA3	2.69e-05	78	94	5	GO:0048787
GeneOntologyCellularComponent	synaptobrevin 2-SNAP-25-syntaxin-1a complex	NAPB NAPA	1.98e-04	5	94	2	GO:0070044
GeneOntologyCellularComponent	hippocampal mossy fiber	MAPK8IP1 SLC4A8	4.14e-04	7	94	2	GO:0097457
GeneOntologyCellularComponent	presynaptic active zone	NRXN1 NRXN2 NAPB NAPA GRIA3	4.41e-04	141	94	5	GO:0048786
Domain	NUDIX_hydrolase_CS	NUDT11 NUDT4 NUDT3 NUDT10	2.42e-07	12	90	4	IPR020084
Domain	NUDIX_BOX	NUDT11 NUDT4 NUDT3 NUDT10	4.98e-06	24	90	4	PS00893
Domain	NUDIX	NUDT11 NUDT4 NUDT3 NUDT10	4.98e-06	24	90	4	PF00293
Domain	NUDIX	NUDT11 NUDT4 NUDT3 NUDT10	6.95e-06	26	90	4	PS51462
Domain	-	NUDT11 NUDT4 NUDT3 NUDT10	9.45e-06	28	90	4	3.90.79.10
Domain	NUDIX_hydrolase_dom-like	NUDT11 NUDT4 NUDT3 NUDT10	9.45e-06	28	90	4	IPR015797
Domain	NUDIX_hydrolase_dom	NUDT11 NUDT4 NUDT3 NUDT10	1.09e-05	29	90	4	IPR000086
Domain	Arylesterase	PON1 PON2	6.87e-05	3	90	2	PF01731
Domain	Arylesterase	PON1 PON2	6.87e-05	3	90	2	IPR002640
Domain	NSF_attach	NAPB NAPA	6.87e-05	3	90	2	IPR000744
Domain	RhoGAP	ARHGAP42 ABR MYO9A INPP5B	2.27e-04	62	90	4	SM00324
Domain	RhoGAP	ARHGAP42 ABR MYO9A INPP5B	2.42e-04	63	90	4	PF00620
Domain	RHOGAP	ARHGAP42 ABR MYO9A INPP5B	2.57e-04	64	90	4	PS50238
Domain	RhoGAP_dom	ARHGAP42 ABR MYO9A INPP5B	2.57e-04	64	90	4	IPR000198
Domain	-	ARHGAP42 ABR MYO9A INPP5B	2.57e-04	64	90	4	1.10.555.10
Domain	TFR_dimer	NAALAD2 TFR2	3.40e-04	6	90	2	PF04253
Domain	-	NAALAD2 TFR2	3.40e-04	6	90	2	1.20.930.40
Domain	TFR-like_dimer_dom	NAALAD2 TFR2	4.75e-04	7	90	2	IPR007365
Domain	Syndecan	NRXN1 NRXN2	4.75e-04	7	90	2	PF01034
Domain	Syndecan/Neurexin_dom	NRXN1 NRXN2	4.75e-04	7	90	2	IPR027789
Domain	SH3_9	ARHGAP42 MAPK8IP1 BAIAP2L1 MAPK8IP2	5.48e-04	78	90	4	PF14604
Domain	LAM_G_DOMAIN	FAT1 NRXN1 NRXN2	8.08e-04	38	90	3	PS50025
Domain	Rho_GTPase_activation_prot	ARHGAP42 ABR MYO9A INPP5B	8.63e-04	88	90	4	IPR008936
Domain	GDS_CDC24_CS	ABR SOS1 SOS2	8.72e-04	39	90	3	IPR001331
Domain	Laminin_G_2	FAT1 NRXN1 NRXN2	9.40e-04	40	90	3	PF02210
Domain	LamG	FAT1 NRXN1 NRXN2	1.24e-03	44	90	3	SM00282
Domain	Peptidase_M28	NAALAD2 TFR2	1.47e-03	12	90	2	IPR007484
Domain	Peptidase_M28	NAALAD2 TFR2	1.47e-03	12	90	2	PF04389
Domain	I-BAR_dom	ARHGAP42 BAIAP2L1	1.73e-03	13	90	2	IPR013606
Domain	Neurexin-like	NRXN1 NRXN2	2.01e-03	14	90	2	IPR003585
Domain	4.1m	NRXN1 NRXN2	2.01e-03	14	90	2	SM00294
Domain	Ras_G-nucl-exch_fac_CS	SOS1 SOS2	2.01e-03	14	90	2	IPR019804
Domain	Laminin_G	FAT1 NRXN1 NRXN2	2.76e-03	58	90	3	IPR001791
Domain	-	ARHGAP42 MAPK8IP1 ABR PHLDA2 MAPK8IP2 SOS1 SOS2	2.81e-03	391	90	7	2.30.29.30
Domain	-	TTC39B TTC23 NAPB NAPA CSTF3	3.27e-03	207	90	5	1.25.40.10
Domain	DH_1	ABR SOS1 SOS2	3.49e-03	63	90	3	PS00741
Domain	PA	NAALAD2 TFR2	3.72e-03	19	90	2	PF02225
Domain	PA_domain	NAALAD2 TFR2	3.72e-03	19	90	2	IPR003137
Domain	RasGEFN	SOS1 SOS2	4.12e-03	20	90	2	SM00229
Domain	Semaphorin	SEMA5B SEMA5A	4.12e-03	20	90	2	IPR027231
Domain	MAGE_N	MAGEA9 MAGEB10	4.12e-03	20	90	2	SM01392
Domain	RhoGEF	ABR SOS1 SOS2	4.33e-03	68	90	3	SM00325
Domain	PH_dom-like	ARHGAP42 MAPK8IP1 ABR PHLDA2 MAPK8IP2 SOS1 SOS2	4.50e-03	426	90	7	IPR011993
Domain	RasGEF_N	SOS1 SOS2	4.54e-03	21	90	2	PF00618
Domain	RhoGEF	ABR SOS1 SOS2	4.69e-03	70	90	3	PF00621
Domain	DH_2	ABR SOS1 SOS2	4.69e-03	70	90	3	PS50010
Domain	DH-domain	ABR SOS1 SOS2	4.88e-03	71	90	3	IPR000219
Domain	-	ABR SOS1 SOS2	4.88e-03	71	90	3	1.20.900.10
Domain	Ras-like_Gua-exchang_fac_N	SOS1 SOS2	4.98e-03	22	90	2	IPR000651
Domain	MAGE_N	MAGEA9 MAGEB10	4.98e-03	22	90	2	PF12440
Domain	RASGEF_NTER	SOS1 SOS2	4.98e-03	22	90	2	PS50212
Domain	MAGE_N	MAGEA9 MAGEB10	4.98e-03	22	90	2	IPR021072
Domain	PH	ARHGAP42 ABR PHLDA2 SOS1 SOS2	5.01e-03	229	90	5	PF00169
Domain	TPR-like_helical_dom	TTC39B TTC23 NAPB NAPA CSTF3	5.39e-03	233	90	5	IPR011990
Domain	RASGEF	SOS1 SOS2	6.92e-03	26	90	2	PS00720
Domain	PID	MAPK8IP1 MAPK8IP2	8.00e-03	28	90	2	PF00640
Domain	Pept_cys_AS	BLMH DNAH8	8.00e-03	28	90	2	IPR000169
Domain	SH3_1	ARHGAP42 MAPK8IP1 BAIAP2L1 MAPK8IP2	8.16e-03	164	90	4	PF00018
Domain	RASGEF_CAT	SOS1 SOS2	8.57e-03	29	90	2	PS50009
Domain	RasGEF	SOS1 SOS2	9.15e-03	30	90	2	PF00617
Domain	-	SOS1 SOS2	9.15e-03	30	90	2	1.10.840.10
Domain	Ras_GEF_dom	SOS1 SOS2	9.15e-03	30	90	2	IPR023578
Domain	RASGEF_cat_dom	SOS1 SOS2	9.15e-03	30	90	2	IPR001895
Domain	RasGEF	SOS1 SOS2	9.15e-03	30	90	2	SM00147
Pathway	REACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL	NUDT11 NUDT4 NUDT3 NUDT10	1.78e-07	10	78	4	MM14709
Pathway	REACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL	NUDT11 NUDT4 NUDT3 NUDT10	1.78e-07	10	78	4	M27051
Pathway	REACTOME_INOSITOL_PHOSPHATE_METABOLISM	NUDT11 NUDT4 NUDT3 INPP5B NUDT10	6.48e-06	48	78	5	M26964
Pathway	REACTOME_INOSITOL_PHOSPHATE_METABOLISM	NUDT11 NUDT4 NUDT3 INPP5B NUDT10	6.48e-06	48	78	5	MM14589
Pubmed	Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.	NUDT11 NUDT4 NUDT3 NUDT10	5.22e-11	4	95	4	12370170
Pubmed	Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.	NUDT11 NUDT4 NUDT10	1.97e-08	3	95	3	12121577
Pubmed	Body mass, polymorphisms in obesity-related genes, and the risk of developing breast cancer among women with benign breast disease.	PON1 PON2 PPARG	3.93e-07	6	95	3	17428620
Pubmed	The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs.	NAPB NAPA GRIA3	3.93e-07	6	95	3	9697855
Pubmed	Single nucleotide polymorphisms in obesity-related genes and all-cause and cause-specific mortality: a prospective cohort study.	PON1 PON2 PPARG	1.09e-06	8	95	3	19818126
Pubmed	[Association of genetic factors with clinical peculiarities of hypertensive disease in patients with burdened familial anamnesis].	PON1 PON2 PPARG	7.03e-06	14	95	3	19254215
Pubmed	Association of paraoxonase gene polymorphisms with sperm parameters.	PON1 PON2	7.38e-06	2	95	2	21127310
Pubmed	The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability.	PRKX PRKY	7.38e-06	2	95	2	7633447
Pubmed	An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.	NUDT11 NUDT10	7.38e-06	2	95	2	12105228
Pubmed	Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear.	PTPRZ1 PTPRQ	7.38e-06	2	95	2	20715155
Pubmed	Paraoxonase genotype and carotid intima-media thickness in children with familial hypercholesterolemia.	PON1 PON2	7.38e-06	2	95	2	16926679
Pubmed	Normalization of gene expression using SYBR green qPCR: a case for paraoxonase 1 and 2 in Alzheimer's disease brains.	PON1 PON2	7.38e-06	2	95	2	21672555
Pubmed	[A search for association between the polymorphic markers of PON1 and PON2 genes and diabetic nephropathy in patients with type I diabetes mellitus].	PON1 PON2	7.38e-06	2	95	2	16080611
Pubmed	Assessment of serum paraoxonase and arylesterase activity in patients with endometrial cancer.	PON1 PON2	7.38e-06	2	95	2	20099504
Pubmed	The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study.	PON1 PON2	7.38e-06	2	95	2	19939821
Pubmed	Lack of association of PON polymorphisms with sporadic ALS in an Italian population.	PON1 PON2	7.38e-06	2	95	2	20381198
Pubmed	Four genetic polymorphisms of paraoxonase gene and risk of coronary heart disease: a meta-analysis based on 88 case-control studies.	PON1 PON2	7.38e-06	2	95	2	21146823
Pubmed	Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.	NRXN1 NRXN2	7.38e-06	2	95	2	30709877
Pubmed	Association of PON1 and PON2 polymorphisms with PON1 activity and significant coronary stenosis in a Tunisian population.	PON1 PON2	7.38e-06	2	95	2	23053877
Pubmed	Expression of PPARγ and paraoxonase 2 correlated with Pseudomonas aeruginosa infection in cystic fibrosis.	PON2 PPARG	7.38e-06	2	95	2	22860094
Pubmed	Detecting the polymorphisms of paraoxonase (PON) cluster in Chinese Han population based on a rapid method.	PON1 PON2	7.38e-06	2	95	2	16185677
Pubmed	Genetic variants of the paraoxonases (PON1 and PON2) in the Chilean population.	PON1 PON2	7.38e-06	2	95	2	15359538
Pubmed	Man to mouse--lessons learned from the distal end of the human X chromosome.	PRKX PRKY	7.38e-06	2	95	2	9414316
Pubmed	Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases.	NUDT11 NUDT10	7.38e-06	2	95	2	12689335
Pubmed	A homologue of the Drosophila Son of sevenless gene maps to mouse chromosome 17.	SOS1 SOS2	7.38e-06	2	95	2	8307589
Pubmed	Profiles of PrKX expression in developmental mouse embryo and human tissues.	PRKX PRKY	7.38e-06	2	95	2	15879576
Pubmed	Serum paraoxonase activity and paraoxonase gene polymorphism in type 2 diabetic patients with or without vascular complications.	PON1 PON2	7.38e-06	2	95	2	12442067
Pubmed	Genetic variations of the paraoxonase gene in patients with coronary artery disease.	PON1 PON2	7.38e-06	2	95	2	11676977
Pubmed	Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1.	MAPK8IP1 MAPK8IP2	7.38e-06	2	95	2	39013462
Pubmed	Association of polymorphisms of paraoxonase 1 and 2 genes, alone or in combination, with bone mineral density in community-dwelling Japanese.	PON1 PON2	7.38e-06	2	95	2	12955589
Pubmed	Oxidative stress-related genes in type 2 diabetes: association analysis and their clinical impact.	PON1 PON2	7.38e-06	2	95	2	25991559
Pubmed	Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T cells leads to PI3K pathway activation and defects in migration.	SOS1 SOS2	7.38e-06	2	95	2	25973715
Pubmed	Polymorphisms of the paraoxonase gene and risk of preterm delivery.	PON1 PON2	7.38e-06	2	95	2	15232408
Pubmed	[Relationship between paraoxonase 1 55 Met/Leu, paraoxonase 2 148 Ala/Gly genetic polymorphisms and coronary artery disease].	PON1 PON2	7.38e-06	2	95	2	16767666
Pubmed	Paraoxonase gene polymorphisms and sporadic ALS.	PON1 PON2	7.38e-06	2	95	2	16822965
Pubmed	Human tissue distribution of paraoxonases 1 and 2 mRNA.	PON1 PON2	7.38e-06	2	95	2	20503442
Pubmed	Paraoxonase gene cluster is a genetic marker for early microvascular complications in type 1 diabetes.	PON1 PON2	7.38e-06	2	95	2	11918623
Pubmed	Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence.	PON1 PON2	7.38e-06	2	95	2	9714608
Pubmed	Requirement of JIP scaffold proteins for NMDA-mediated signal transduction.	MAPK8IP1 MAPK8IP2	7.38e-06	2	95	2	17875667
Pubmed	Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies.	PON1 PON2	7.38e-06	2	95	2	15001326
Pubmed	Polymorphisms of pon1 and pon2 genes in hemodialyzed patients.	PON1 PON2	7.38e-06	2	95	2	21620813
Pubmed	Signal transduction cross talk mediated by Jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes.	MAPK8IP1 MAPK8IP2	7.38e-06	2	95	2	19564410
Pubmed	Paraoxonase, a cardioprotective enzyme: continuing issues.	PON1 PON2	7.38e-06	2	95	2	15166781
Pubmed	[Association between paraoxonase-1 and paraoxonase-2 polymorphisms and the risk of acute myocardial infarction].	PON1 PON2	7.38e-06	2	95	2	18361900
Pubmed	Associations between genetic polymorphisms of paraoxonase genes and coronary artery disease in a Taiwanese population.	PON1 PON2	7.38e-06	2	95	2	23742759
Pubmed	Interactions and associations of paraoxonase gene cluster polymorphisms with myocardial infarction in a Pakistani population.	PON1 PON2	7.38e-06	2	95	2	17309646
Pubmed	Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras.	SOS1 SOS2	7.38e-06	2	95	2	1631150
Pubmed	Paraoxonase gene polymorphisms and stroke severity.	PON1 PON2	7.38e-06	2	95	2	19930448
Pubmed	Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.	NRXN1 NRXN2	7.38e-06	2	95	2	1621094
Pubmed	SOS2 Comes to the Fore: Differential Functionalities in Physiology and Pathology.	SOS1 SOS2	7.38e-06	2	95	2	34205562
Pubmed	PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation.	PRKX PRKY	7.38e-06	2	95	2	21684272
Pubmed	Paraoxonase gene polymorphism in south-western Korean population.	PON1 PON2	7.38e-06	2	95	2	19654933
Pubmed	Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females.	PRKX PRKY	7.38e-06	2	95	2	9302280
Pubmed	The paraoxonase gene polymorphism in stroke patients and lipid profile.	PON1 PON2	7.38e-06	2	95	2	17854416
Pubmed	The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1.	SOS1 SOS2	7.38e-06	2	95	2	9372945
Pubmed	Association of paraoxonase polymorphisms with carotid artery atherosclerosis in essential hypertension patients.	PON1 PON2	7.38e-06	2	95	2	24301778
Pubmed	Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism.	MAPK8IP1 MAPK8IP2	7.38e-06	2	95	2	12023290
Pubmed	Paraoxonase 1 and 2 gene variants and the ischemic stroke risk in Gran Canaria population: an association study and meta-analysis.	PON1 PON2	7.38e-06	2	95	2	26978533
Pubmed	Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.	NRXN1 NRXN2	7.38e-06	2	95	2	26595880
Pubmed	Polymorphisms of paraoxonase 1 and 2 genes and the risk of multiple sclerosis in the Polish population.	PON1 PON2	7.38e-06	2	95	2	23487294
Pubmed	Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia.	SOS1 SOS2	7.38e-06	2	95	2	36010887
Pubmed	Chromosomal localization of two genes encoding human ras exchange factors: SOS1 maps to the 2p22-->p16 region and SOS2 to the 14q21-->q22 region of the human genome.	SOS1 SOS2	7.38e-06	2	95	2	8275713
Pubmed	Paraoxonase gene polymorphism and the risk for Alzheimer's disease in the polish population.	PON1 PON2	7.38e-06	2	95	2	21757906
Pubmed	A novel murine PKA-related protein kinase involved in neuronal differentiation.	PRKX PRKY	7.38e-06	2	95	2	10729225
Pubmed	Isolation of novel murine maternal mRNAs regulated by cytoplasmic polyadenylation.	IPO8 MCM4	7.38e-06	2	95	2	1628827
Pubmed	Risk of carotid atherosclerosis is associated with low serum paraoxonase (PON1) activity among arsenic exposed residents in Southwestern Taiwan.	PON1 PON2	7.38e-06	2	95	2	19371607
Pubmed	Association between the severity of angiographic coronary artery disease and paraoxonase gene polymorphisms in the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study.	PON1 PON2	7.38e-06	2	95	2	12454802
Pubmed	Paraoxonase (PON)1 192R allele carriage is associated with reduced risk of inflammatory bowel disease.	PON1 PON2	7.38e-06	2	95	2	17436100
Pubmed	Association of paraoxonase gene polymorphisms with diabetic nephropathy and retinopathy.	PON1 PON2	7.38e-06	2	95	2	24100645
Pubmed	A systematic meta-analysis of genetic association studies for diabetic retinopathy.	PON1 PON2 PPARG	2.18e-05	20	95	3	19587357
Pubmed	Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.	NRXN1 NRXN2	2.21e-05	3	95	2	34133920
Pubmed	SNAP family of NSF attachment proteins includes a brain-specific isoform.	NAPB NAPA	2.21e-05	3	95	2	8455721
Pubmed	Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.	NRXN1 NRXN2	2.21e-05	3	95	2	38891114
Pubmed	PON1 M/L55 mutation protects high-risk patients against coronary artery disease.	PON1 PON2	2.21e-05	3	95	2	14996478
Pubmed	Paraoxonase and atherosclerosis-related cardiovascular diseases.	PON1 PON2	2.21e-05	3	95	2	27771368
Pubmed	A new beat for the SNARE drum.	NAPB NAPA	2.21e-05	3	95	2	9695844
Pubmed	Extensive association analysis between polymorphisms of PON gene cluster with coronary heart disease in Chinese Han population.	PON1 PON2	2.21e-05	3	95	2	12588779
Pubmed	Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency.	PRKX PRKY	2.21e-05	3	95	2	17980165
Pubmed	Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia.	NRXN1 NRXN2	2.21e-05	3	95	2	21424692
Pubmed	Paraoxonase gene mutations in amyotrophic lateral sclerosis.	PON1 PON2	2.21e-05	3	95	2	20582942
Pubmed	The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.	NRXN1 NRXN2	2.21e-05	3	95	2	30858964
Pubmed	Paraoxonase 1 gene polymorphisms influence clinical features of open-angle glaucoma.	PON1 PON2	2.21e-05	3	95	2	16411107
Pubmed	FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12-->q13.	PRKX PRKY	2.21e-05	3	95	2	9154127
Pubmed	[Study of the association between paraoxonase1 55 Met/Leu, paraoxonase2 148 Ala/Gly and manganese superoxide dismutase (MnSOD) 9 Ala/Val genetic polymorphisms and coronary heart disease].	PON1 PON2	2.21e-05	3	95	2	17299970
Pubmed	Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone.	PON1 PON2	2.21e-05	3	95	2	18347034
Pubmed	Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.	SOS1 SOS2	2.21e-05	3	95	2	24043312
Pubmed	Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.	NRXN1 NRXN2	2.21e-05	3	95	2	28013231
Pubmed	[Paraoxonase: The Universal Factor of Antioxidant Defense in Human Body].	PON1 PON2	2.21e-05	3	95	2	29308836
Pubmed	alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.	NRXN1 NRXN2	2.21e-05	3	95	2	16406382
Pubmed	Inflammation, infection, cancer and all that…the role of paraoxonases.	PON1 PON2	2.21e-05	3	95	2	25038992
Pubmed	Ocular distribution of antioxidant enzyme paraoxonase & its alteration in cataractous lens & diabetic retina.	PON1 PON2	2.21e-05	3	95	2	28862184
Pubmed	Association Between Paraoxonase Gene Polymorphisms and Intracerebral Hemorrhage in a Korean Population.	PON1 PON2	2.21e-05	3	95	2	26227792
Pubmed	Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.	NRXN1 NRXN2	2.21e-05	3	95	2	31812984
Pubmed	The three-gene paraoxonase family: physiologic roles, actions and regulation.	PON1 PON2	2.21e-05	3	95	2	20934178
Pubmed	Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS.	SOS1 SOS2	2.21e-05	3	95	2	12628188
Pubmed	The N-ethylmaleimide-sensitive fusion protein (NSF) is preferentially expressed in the nervous system.	NAPB NAPA	2.21e-05	3	95	2	8013662
Pubmed	Comparative expression analysis reveals differences in the regulation of intestinal paraoxonase family members.	PON1 PON2	2.21e-05	3	95	2	19401157
Pubmed	Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients.	PON1 PON2	2.21e-05	3	95	2	19540141
Pubmed	Paraoxonase gene polymorphisms and haplotype analysis in a stroke population.	PON1 PON2	2.21e-05	3	95	2	16551349
Pubmed	Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis.	SOS1 SOS2	2.21e-05	3	95	2	29844066
Cytoband	7q21.3	DBF4 ASNS PON1 PON2	1.34e-06	39	95	4	7q21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr7q21	DBF4 ASNS PON1 PON2	5.28e-04	178	95	4	chr7q21
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	BAIAP2L1 EFCAB10 COPS6 TFR2	1.14e-03	219	95	4	chr7q22
Cytoband	Xp21.3	MAGEB10 PPP4R3C	1.66e-03	29	95	2	Xp21.3
Cytoband	6p21.2	NUDT3 DNAH8	2.55e-03	36	95	2	6p21.2
GeneFamily	Nudix hydrolase family	NUDT11 NUDT4 NUDT3 NUDT10	1.53e-06	24	65	4	667
GeneFamily	Paraoxonases	PON1 PON2	3.81e-05	3	65	2	463
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ABR SOS1 SOS2	1.73e-03	66	65	3	722
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA5B SEMA5A	2.32e-03	20	65	2	736
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRZ1 PTPRQ	2.56e-03	21	65	2	813
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	TDRD7 RLF UBR2 IBTK FAT1 SLC11A2 DBF4 BUB1B PKD2 SEMA5A TRAM2 PHF21A SOS1 SOS2	1.91e-06	856	93	14	M4500
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	SLC25A46 BLMH UBR2 IBTK SLC11A2 NUDT3 DBF4 ASNS NAPA MCM4 PRPF38B TRAM2 COPS6 LRRC8D TFCP2 SOS2	5.40e-06	1215	93	16	M41122
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	TDRD7 UBR2 IBTK FAT1 BUB1B PKD2 SEMA5A TRAM2 PHF21A SOS1	6.20e-06	466	93	10	M13522
Coexpression	GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN	IBTK ATG10 NUDT4 VKORC1L1 BUB1B PON2 MCM4	7.38e-06	200	93	7	M3067
Coexpression	MATSUDA_NATURAL_KILLER_DIFFERENTIATION	HEXA SOCS2 TTC39B ASNS SYTL2 BUB1B DOCK7 SLC6A15 DNAH8 PHF21A	8.95e-06	486	93	10	M18517
Coexpression	MATSUDA_NATURAL_KILLER_DIFFERENTIATION	HEXA SOCS2 TTC39B ASNS SYTL2 BUB1B DOCK7 SLC6A15 DNAH8 PHF21A	1.60e-05	520	93	10	MM1008
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HSERT	CD2 SLC4A8 ABR NRXN1 NRXN2 NAPB SYTL2 SLC6A15 MAPK8IP2	3.22e-05	450	93	9	M39072
Coexpression	TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP	NUDT11 NUDT10 PHLDA2	5.49e-05	21	93	3	MM915
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA	CD2 SLC4A8 NRXN1 NRXN2 ASNS GRIA3 SLC6A15 PRKX TFR2	7.94e-05	506	93	9	M39067
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_UP	ADAD1 MAPK8IP1 TTC39B PTPRZ1 SEMA5A PRPF38B	8.04e-05	200	93	6	M4024
Coexpression	GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_UP	SOCS2 S1PR5 NAALAD2 NUDT4 SYTL2 USP48	8.04e-05	200	93	6	M9284
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 NRXN2 SEMA5B PTPRZ1 GRIA3 SEMA5A FLRT1	1.39e-07	184	95	7	278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 NRXN2 SEMA5B PTPRZ1 GRIA3 SEMA5A FLRT1	1.39e-07	184	95	7	8d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 SEMA5B PTPRZ1 GRIA3 SEMA5A FLRT1	3.33e-06	190	95	6	9b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 SEMA5B PTPRZ1 GRIA3 SEMA5A FLRT1	3.33e-06	190	95	6	d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCell	10x5'v1-week_14-16-Lymphocytic_NK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	S1PR5 TTC39B CD2 SYTL2 PRKX IL23R	3.76e-06	194	95	6	5a859885c0f9b8554b0d203e371c70928ad4418f
ToppCell	10x5'v1-week_14-16-Lymphocytic_NK-T_NK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	S1PR5 TTC39B CD2 SYTL2 PRKX IL23R	3.76e-06	194	95	6	7d35ac70ba966eb1fee4197f7de6d6116326a442
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FSIP2 SEMA5B PTPRZ1 GRIA3 SEMA5A	2.05e-05	155	95	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	S1PR5 CD2 DBF4 SYTL2 TRAM2	2.39e-05	160	95	5	6b0faaa371650563f585722f5b2fb319e124ec38
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP42 NAALAD2 SLC4A8 NRXN1 MCM4	2.94e-05	167	95	5	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEXA MCM4 PPARG LRRC8D ABHD12	3.02e-05	168	95	5	a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP42 NAALAD2 SLC4A8 NRXN1 SEMA5B	3.20e-05	170	95	5	1f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP42 FAT1 SEMA5B SYTL2 SEMA5A	3.57e-05	174	95	5	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP42 SEMA5B SYTL2 SEMA5A AWAT2	3.98e-05	178	95	5	066dbc4cc2083c549d98122ed44707127f34d582
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	ARHGAP42 SEMA5B SYTL2 SEMA5A PPARG	4.31e-05	181	95	5	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	ARHGAP42 SEMA5B SYTL2 SEMA5A PPARG	4.42e-05	182	95	5	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	ARHGAP42 FAT1 PTPRZ1 PTPRQ SEMA5A	4.42e-05	182	95	5	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	BLMH S1PR5 NUDT11 PTPRZ1 PRKX	4.66e-05	184	95	5	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 SYTL2 PKD2 SEMA5A PRKX	4.66e-05	184	95	5	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	Mesenchymal_cells-Ng2+_MSCs\|Mesenchymal_cells / Lineage and Cell class	FAT1 NUDT4 PTPRZ1 SEMA5A TFR2	5.03e-05	187	95	5	e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5B PTPRZ1 GRIA3 SEMA5A FLRT1	5.16e-05	188	95	5	a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 NRXN2 SEMA5B PTPRZ1 FLRT1	5.16e-05	188	95	5	006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5B PTPRZ1 GRIA3 SEMA5A FLRT1	5.16e-05	188	95	5	c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 NRXN2 SEMA5B PTPRZ1 FLRT1	5.16e-05	188	95	5	d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ARHGAP42 S1PR5 SEMA5B SYTL2 SEMA5A	5.29e-05	189	95	5	9c2492c38f27e4c699b40680652e4c64911cce52
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	S1PR5 NUDT4 SEMA5B SYTL2 SEMA5A	5.29e-05	189	95	5	d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 MYO9A SYTL2 PON2 PRKX	5.43e-05	190	95	5	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRXN1 NRXN2 PTPRZ1 PON1 SEMA5A	5.43e-05	190	95	5	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP42 FAT1 SEMA5B SYTL2 SEMA5A	5.43e-05	190	95	5	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 MYO9A SYTL2 PON2 PRKX	5.56e-05	191	95	5	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5B PTPRZ1 GRIA3 SEMA5A FLRT1	5.56e-05	191	95	5	ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA5B PTPRZ1 GRIA3 SEMA5A FLRT1	5.56e-05	191	95	5	478e8341ee03b05501e2233e02cef5f97492c95d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 MYO9A SYTL2 PON2 PRKX	5.56e-05	191	95	5	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	ARHGAP42 FAT1 SEMA5B SYTL2 SEMA5A	5.56e-05	191	95	5	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	P15-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NUDT4 SEMA5B PTPRZ1 SYTL2 SEMA5A	5.70e-05	192	95	5	a476895b7b252c388d6346eacbc72f0115b1443e
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	S1PR5 NUDT4 SEMA5B SYTL2 SEMA5A	5.84e-05	193	95	5	47d189bac0ef4df2f5c6dd987e46aca85bd7e2af
ToppCell	10x5'v1-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	S1PR5 CD2 SYTL2 PRKX IL23R	5.84e-05	193	95	5	46f94a1062b098205e8ce3ed380c0202a4d97678
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP42 NAALAD2 NRXN1 SEMA5B PTPRZ1	5.84e-05	193	95	5	7386fadc13a437f3b0c99b5d116cd3c5f893529c
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRXN1 NRXN2 PTPRZ1 DBF4 BUB1B	5.99e-05	194	95	5	7a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP42 NAALAD2 NRXN1 SEMA5B PTPRZ1	5.99e-05	194	95	5	6a4e7f1bf67bad94cd8c472e7c66798b0c25ba01
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP42 S1PR5 SEMA5B SYTL2 SEMA5A	5.99e-05	194	95	5	7a7406c3b021aeafde423d20290c681c3e8ea0a6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 MYO9A SYTL2 RNF213 PRKX	5.99e-05	194	95	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP42 NAALAD2 SLC4A8 NRXN1 NRXN2	6.14e-05	195	95	5	4a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP42 NAALAD2 SLC4A8 NRXN1 NRXN2	6.14e-05	195	95	5	7a32a8535c29b819dacba901d0658280a2631c94
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP42 S1PR5 SEMA5B SYTL2 PHLDA2	6.29e-05	196	95	5	624f700daea48d9bad4cc554f4776bd809ae1e54
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRXN1 NRXN2 PTPRZ1 GRIA3 SEMA5A	6.29e-05	196	95	5	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRXN1 NRXN2 PTPRZ1 GRIA3 SEMA5A	6.29e-05	196	95	5	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 BAIAP2L1 AP1S3 MYO9A SYTL2	6.44e-05	197	95	5	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	FAT1 PON2 RNF213 SEMA5A TRAM2	6.60e-05	198	95	5	bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	FAT1 PON2 RNF213 SEMA5A TRAM2	6.60e-05	198	95	5	6372e65242236c497d9b3be147092897c1609d22
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CATSPERE NRXN2 PTPRZ1 GRIA3 SEMA5A	6.60e-05	198	95	5	02d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S1PR5 CD2 NUDT11 SYTL2 RNF213	6.75e-05	199	95	5	63e632b06e13d2bcde5a00a51962bafdf60fd6c6
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRXN1 PTPRZ1 PON2 NAPA COPS6	6.75e-05	199	95	5	a900ef002e1ae583b70be0253d8c44dae6754916
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGAP42 FAT1 NRXN2 SYTL2 GRIA3	6.75e-05	199	95	5	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	severe-gd_T\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	S1PR5 CD2 SYTL2 RNF213 IL23R	6.75e-05	199	95	5	e5a17a9f8f3be05d6abe1116607d17633df3c7ef
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGAP42 FAT1 SYTL2 PKD2 GRIA3	6.92e-05	200	95	5	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FAT1 ABR SEMA5B SYTL2 NUDT10	6.92e-05	200	95	5	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 FAT1 SYTL2 PKD2 GRIA3	6.92e-05	200	95	5	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 FAT1 SYTL2 PKD2 GRIA3	6.92e-05	200	95	5	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	CD2 ABR NRXN1 PTPRZ1 ASNS	6.92e-05	200	95	5	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN1 NRXN2 PTPRZ1 FLRT1 MAPK8IP2	6.92e-05	200	95	5	553e9612874480f4d2a45671462e266cd0a09321
ToppCell	tumor_Lung-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	NUDT11 CATSPERE EFCAB10 CASP6	2.69e-04	146	95	4	8b2d104fdb0fdb09410450c6c651e1edb00cae44
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOCS2 S1PR5 CD2 SYTL2	2.99e-04	150	95	4	a3a4710820a244116a26204f40e7113a1e7236c5
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOCS2 S1PR5 CD2 SYTL2	2.99e-04	150	95	4	13dcd519dacf08d5852aa3e029e0a3308de07321
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOCS2 PFN4 PKD2 PON1	3.14e-04	152	95	4	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOCS2 PFN4 PKD2 PON1	3.14e-04	152	95	4	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	Children_(3_yrs)-Immune-mast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OR1L8 ASNS SYTL2 IL23R	3.22e-04	153	95	4	d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	FSIP2 MYO1H TRAM2 NUDT4B	3.90e-04	161	95	4	048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	S1PR5 NUDT11 PTPRZ1 NUDT10	3.90e-04	161	95	4	da9eecf919866a9c579d7a707a996cf335213134
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	S1PR5 NUDT11 PTPRZ1 NUDT10	3.90e-04	161	95	4	d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCell	PND07-28-samps-Myeloid-Macrophage\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	HEXA CD2 PPARG ABHD12	4.00e-04	162	95	4	7c73fe8388af370461e04097cf145cbc9847285b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S1PR5 CD2 MAGEB10 SYTL2	4.00e-04	162	95	4	3b89c3758835b7b9f9d4fb0bc8ed06da382fe48b
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A8 NUDT4 MYO9A PRKX	4.09e-04	163	95	4	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S1PR5 ABR LRRC8D ABHD12	4.19e-04	164	95	4	b77995958c938e10a526118f75d78cee72e0b207
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	S1PR5 EFCAB10 SEMA5B SYTL2	4.28e-04	165	95	4	369d77a80d6401e85ea3121ab5a252f67d5f157e
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	CPPED1 NRXN1 PTPRZ1 MAPK8IP2	4.28e-04	165	95	4	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRXN1 PTPRQ SEMA5A TFR2	4.38e-04	166	95	4	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRXN1 PTPRQ SEMA5A TFR2	4.38e-04	166	95	4	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	BLMH S1PR5 CD2 NRXN1	4.48e-04	167	95	4	ded4d6cccd3660662f12cf5a512de31d26325f1b
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN1 NRXN2 PTPRZ1 FLRT1	4.69e-04	169	95	4	2456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	CPPED1 NRXN1 PTPRZ1 MAPK8IP2	4.69e-04	169	95	4	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEXA S1PR5 ABR BUB1B	4.79e-04	170	95	4	7534ac69ca3a378df78d61c284e89bc96a71a4a8
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP42 S1PR5 SEMA5B SYTL2	4.79e-04	170	95	4	d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DBF4 BUB1B PPARG ABHD12	4.90e-04	171	95	4	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	S1PR5 SLC9C1 SEMA5B SYTL2	4.90e-04	171	95	4	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	BAIAP2L1 AP1S3 DOCK7 SOS1	5.12e-04	173	95	4	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	IIH-CD8-naive_CD4\|IIH / Condition, Cell_class and T cell subcluster	TTC39B SYTL2 GRIA3 USP48	5.12e-04	173	95	4	4f2843371d18af766c1892529ce286f56c956fde
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	S1PR5 CD2 SYTL2 SOS1	5.12e-04	173	95	4	36a471576a9d2325066bb14c2f2cd89c67b92915
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGAP42 NRXN2 NUDT10 PPARG	5.23e-04	174	95	4	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN1 PTPRZ1 TMEM145 FLRT1	5.23e-04	174	95	4	412ccc099028a372b9d953363984c2da54b2187f
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S1PR5 PPARG LRRC8D ABHD12	5.34e-04	175	95	4	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	S1PR5 CD2 SYTL2 IL23R	5.34e-04	175	95	4	cc2428150987911d0d382e8177918724aa69f85c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 PTPRZ1 TMEM145 SEMA5A	5.34e-04	175	95	4	d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP42 NAALAD2 NRXN1 SEMA5B	5.34e-04	175	95	4	15c69dd5635c9251c535f1e22467712e9667ae92
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CD2 BAIAP2L1 PPARG PHLDA2	5.34e-04	175	95	4	6374ab186d7ccf7f6dfb858267edba8962789e15
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 PTPRZ1 TMEM145 SEMA5A	5.34e-04	175	95	4	1d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	S1PR5 CD2 SYTL2 RNF213	5.46e-04	176	95	4	5914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	S1PR5 CD2 SYTL2 IL23R	5.46e-04	176	95	4	003076f1a983409ddf31b9c19e61c1facdd72566
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC11A2 RNF213 PPARG SOS2	5.58e-04	177	95	4	8dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC11A2 RNF213 PPARG SOS2	5.58e-04	177	95	4	767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC11A2 RNF213 PPARG SOS2	5.58e-04	177	95	4	5ef2527e9b41e62f1724cdabaad9d8979266bb7d
Drug	AC1Q6SGD	HEXA PON1 PON2	6.99e-07	5	95	3	CID000016775
Drug	vamidothion	HEXA PON1 PON2	6.99e-07	5	95	3	CID000560193
Drug	1,5,9-triazacyclododecane	BLMH PON1 PON2	6.99e-07	5	95	3	CID000470778
Drug	diethyl 4-methylbenzylphosphonate	HEXA PON1 PON2	1.39e-06	6	95	3	CID000003050
Drug	PP-IP(5	NUDT11 NUDT4 NUDT3 NUDT10	1.96e-06	22	95	4	CID000127296
Drug	5-nitro-2-furaldehyde	SOCS2 MAPK8IP1 MAPK8IP2	1.51e-05	12	95	3	CID000012774
Drug	Ap6A	NUDT11 NUDT4 NUDT3 NUDT10	1.51e-05	36	95	4	CID000123694
Drug	diadenosine 5',5''''-P1,P6-hexaphosphate	NUDT11 NUDT10	1.72e-05	2	95	2	ctd:C070070
Drug	NSC 2885	PON1 PON2	1.72e-05	2	95	2	CID000070425
Drug	adenosine 5'-tetraphosphate	NUDT11 NUDT10	1.72e-05	2	95	2	ctd:C017991
Drug	methyl phenyl phosphate	PON1 PON2	1.72e-05	2	95	2	CID000301276
Drug	BcdA	PON1 PON2	1.72e-05	2	95	2	CID000065116
Drug	adenosine 5'-pentaphosphate	NUDT11 NUDT10	1.72e-05	2	95	2	ctd:C048567
Drug	5,6,7,8-tetrahydroxy-4-oxooctanal	PON1 PON2	1.72e-05	2	95	2	ctd:C550995
Drug	Picrotoxinin [17617-45-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A	INPP5B PKD2 PSMD1 TRAM2 PRKX PHF21A SOS2	1.96e-05	198	95	7	2816_DN
Drug	Fp-O	HEXA MAPK8IP1 PON1 PON2 MAPK8IP2	3.21e-05	87	95	5	CID000024267
Drug	d22-29	PON1 PON2	5.15e-05	3	95	2	CID000077709
Drug	p-bromobenzoyl chloride	MAPK8IP1 MAPK8IP2	5.15e-05	3	95	2	CID000068515
Drug	2bq6	MAPK8IP1 MAPK8IP2	5.15e-05	3	95	2	CID006540266
Drug	O,O-diethyl O-(4-carbamoylphenyl)phosphate	PON1 PON2	5.15e-05	3	95	2	CID000151413
Drug	AC1L1DKE	NUDT11 NUDT4 NUDT3 NUDT10	8.24e-05	55	95	4	CID000002388
Drug	pralidoxime	SLC11A2 PON1 PON2 TFR2	8.24e-05	55	95	4	CID005353894
Drug	5-hydroxyeicosatetraenoic acid lactone	PON1 PON2	1.03e-04	4	95	2	ctd:C047651
Drug	o-nitrophenylbutyrate	PON1 PON2	1.03e-04	4	95	2	CID000075600
Drug	phenyl acetate	PON1 PON2	1.03e-04	4	95	2	ctd:C570634
Drug	P(1),P(5)-di(adenosine-5'-)pentaphosphate	NUDT11 NUDT10	1.03e-04	4	95	2	ctd:C012275
Drug	4-hydroxyphenyl acetate	PON1 PON2	1.03e-04	4	95	2	CID000096009
Drug	Tetriso	PON1 PON2	1.03e-04	4	95	2	CID000161384
Drug	coroxon	PON1 PON2	1.03e-04	4	95	2	CID000009453
Drug	methyl phenylphosphonate	PON1 PON2	1.03e-04	4	95	2	CID000024913
Drug	dalcetrapib	PON1 PON2 PPARG	1.17e-04	23	95	3	CID006918540
Drug	phenylacetic acid	NAPB PON1 PON2 NAPA PPARG	1.27e-04	116	95	5	CID000000999
Disease	high density lipoprotein particle size measurement	TTC39B NUDT3 BAIAP2L1 MYO1H PON1 PPARG	1.58e-05	170	92	6	EFO_0008592
Disease	level of serum paraoxonase/arylesterase 1 in blood serum	PON1 PON2	2.88e-05	3	92	2	OBA_2044998
Disease	free cholesterol in very large HDL measurement	TTC39B DOCK7 PON1 PPARG	4.30e-05	62	92	4	EFO_0022273
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	TTC39B NUDT3 BAIAP2L1 MYO1H DOCK7 PON1 PON2	5.07e-05	307	92	7	EFO_0004612, EFO_0020946
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	TTC39B CPPED1 NUDT3 MYO1H DOCK7 PON1 PPARG	5.96e-05	315	92	7	EFO_0004612, EFO_0008591
Disease	lipid measurement, high density lipoprotein cholesterol measurement	TTC39B CPPED1 NUDT3 BAIAP2L1 MYO1H DOCK7 PON1	7.98e-05	330	92	7	EFO_0004529, EFO_0004612
Disease	free cholesterol in large HDL measurement	TTC39B MYO1H PON1 PPARG	1.11e-04	79	92	4	EFO_0022157
Disease	renal system measurement, uric acid measurement	NRXN2 PKD2	1.43e-04	6	92	2	EFO_0004742, EFO_0004761
Disease	Polycystic kidney disease, type 2	PKD2 PPARG	2.00e-04	7	92	2	C2751306
Disease	Polycystic Kidney, Type 1 Autosomal Dominant Disease	PKD2 PPARG	2.66e-04	8	92	2	C0887850
Disease	Polycystic Kidney, Autosomal Dominant	PKD2 PPARG	3.41e-04	9	92	2	C0085413
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	TTC39B SLC4A8 MYO1H DOCK7 PON1 PPARG	3.80e-04	303	92	6	EFO_0004612, EFO_0020945
Disease	Metabolic Diseases	PON1 PPARG	4.26e-04	10	92	2	C0025517
Disease	Optic Atrophy	SLC25A46 ABHD12	4.26e-04	10	92	2	C0029124
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	TTC39B CPPED1 NUDT3 MYO1H DOCK7 PON1	4.66e-04	315	92	6	EFO_0004574, EFO_0004612
Disease	phospholipid measurement, high density lipoprotein cholesterol measurement	TTC39B CPPED1 BAIAP2L1 MYO1H DOCK7 PON1	5.15e-04	321	92	6	EFO_0004612, EFO_0004639
Disease	Dental enamel hypoplasia	SEMA5B DHX37	6.22e-04	12	92	2	EFO_1001304
Disease	Hereditary hemochromatosis	SLC11A2 TFR2	6.22e-04	12	92	2	C0392514
Disease	Hemochromatosis	SLC11A2 TFR2	6.22e-04	12	92	2	C0018995
Disease	uric acid measurement	NAALAD2 NRXN2 MYO9A SYTL2 PKD2 FLRT1 PPARG SOS2	6.47e-04	610	92	8	EFO_0004761
Disease	Hyperlipoproteinemia Type IIb	PON1 PON2	7.33e-04	13	92	2	C1704417
Disease	Psoriasis	AP1S3 PPARG IL23R	7.60e-04	57	92	3	C0033860
Disease	Pustulosis of Palms and Soles	AP1S3 PPARG IL23R	7.60e-04	57	92	3	C0030246
Disease	anemia (is_implicated_in)	SLC11A2 PON1	8.54e-04	14	92	2	DOID:2355 (is_implicated_in)
Disease	polycystic kidney disease (implicated_via_orthology)	PKD2 PPARG	8.54e-04	14	92	2	DOID:0080322 (implicated_via_orthology)
Disease	ovarian carcinoma (is_implicated_in)	SOCS2 CASP6	9.83e-04	15	92	2	DOID:4001 (is_implicated_in)
Disease	Malignant neoplasm of liver	SLC11A2 ATP7B ASNS PPARG	1.03e-03	142	92	4	C0345904
Disease	Liver neoplasms	SLC11A2 ATP7B ASNS PPARG	1.03e-03	142	92	4	C0023903
Disease	Headache	MYO1H RNF213 SOS1	1.06e-03	64	92	3	HP_0002315
Disease	neurodegenerative disease (implicated_via_orthology)	UBR2 PON1 PON2 GRIA3	1.12e-03	145	92	4	DOID:1289 (implicated_via_orthology)
Disease	Hyperlipoproteinemia Type IIa	PON1 PON2	1.12e-03	16	92	2	C0745103
Disease	total lipids in very large HDL measurement	TTC39B PON1 PPARG	1.16e-03	66	92	3	EFO_0022312
Disease	phospholipids in very large HDL measurement	TTC39B PON1 PPARG	1.16e-03	66	92	3	EFO_0022298
Disease	cholesterol in very large HDL measurement	TTC39B PON1 PPARG	1.32e-03	69	92	3	EFO_0022229
Disease	Hypercholesterolemia, Familial	PON1 PON2	1.42e-03	18	92	2	C0020445
Disease	Lipoidosis	ASNS PPARG	1.59e-03	19	92	2	C0023794
Disease	Noonan-Like Syndrome With Loose Anagen Hair	SOS1 SOS2	1.59e-03	19	92	2	C3501846
Disease	Noonan syndrome-like disorder with loose anagen hair	SOS1 SOS2	1.59e-03	19	92	2	C1843181
Disease	Cardio-facio-cutaneous syndrome	SOS1 SOS2	1.59e-03	19	92	2	C1275081
Disease	Systemic Scleroderma	S1PR5 PHF21A	1.59e-03	19	92	2	C0036421
Disease	Costello syndrome (disorder)	SOS1 SOS2	1.59e-03	19	92	2	C0587248
Disease	total lipids in large HDL	TTC39B MYO1H PPARG	1.62e-03	74	92	3	EFO_0022189
Disease	type 2 diabetes mellitus (is_implicated_in)	MAPK8IP1 PON1 PON2 PPARG	2.05e-03	171	92	4	DOID:9352 (is_implicated_in)
Disease	LEOPARD Syndrome	SOS1 SOS2	2.13e-03	22	92	2	C0175704
Disease	lipoprotein measurement, phospholipid measurement	TTC39B MYO1H DOCK7	2.41e-03	85	92	3	EFO_0004639, EFO_0004732
Disease	fatty acid measurement	UBR2 TTC39B MYO1H DOCK7 SLC6A15 PHF21A	2.46e-03	436	92	6	EFO_0005110
Disease	Sjogren's syndrome (is_marker_for)	PON1 IL23R	2.54e-03	24	92	2	DOID:12894 (is_marker_for)
Disease	Dyslipidemias	ATP7B PPARG	2.54e-03	24	92	2	C0242339
Disease	Dyslipoproteinemias	ATP7B PPARG	2.54e-03	24	92	2	C0598784
Disease	Noonan Syndrome	SOS1 SOS2	2.54e-03	24	92	2	C0028326
Disease	cholesteryl ester measurement, high density lipoprotein cholesterol measurement	TTC39B CPPED1 NUDT3 DOCK7 PON1	2.97e-03	312	92	5	EFO_0004612, EFO_0010351

Protein segments in the cluster

Peptide	Gene	Start	Entry
IETIFYKIQDIYEIH	ABR	136	Q12979
SEYITHEITVLIIYN	BUB1B	851	O60566
EYQTKVDGEIILHLY	ASNS	91	P08243
IIHEVFIDYYGDILV	CATSPERE	496	Q5SY80
SHTVEEKIIIDKEYY	COPS6	91	Q7L5N1
YVYSLVILVVAVAEK	ATP7B	741	P35670
HLKTDDQDIYKVSIY	CD2	96	P06729
TALHYAVYSEILSVV	ANKRD30A	141	Q9BXX3
VVLSELAYVSKVHYE	ADAD1	186	Q96M93
ETAAASEVIKYEYHV	ATG10	86	Q9H0Y0
GVKILHIDDIRYYIE	DBF4	166	Q9UBU7
HRTYVYVLTVTELLE	NUDT10	91	Q8NFP7
RVELYKVLSSLGYHV	ABHD12	186	Q8N2K0
LEIVHRYVELLDKYF	AP1S3	81	Q96PC3
YYAVVKVDTEVGHVI	FAT1	2086	Q14517
IAVKEYVLVYFHTLT	GDAP2	381	Q9NXN4
VYKTHIDVIHYRKTD	MCM4	411	P33991
AHAETSYEKVINYLV	MAGEA9	276	P43362
VDEKVIILVHYLLYK	MAGEB10	111	Q96LZ2
KHRTYVYVLTVTEIL	NUDT4B	91	A0A024RBG1
KVILDYLYTDEAVVI	IBTK	821	Q9P2D0
YDSVKYTLVVDEHAQ	MAPK8IP1	376	Q9UQF2
DASLVYDAVKYTLVV	MAPK8IP2	501	Q13387
YDAVKYTLVVDEHTQ	MAPK8IP2	506	Q13387
HIYAYDAKIEIQTLT	CASP6	126	P55212
VIHVLSKEIEVDYHF	FSIP2	3611	Q5CZC0
VDLAYEIAKHVRIKY	GRIA3	456	P42263
HRTYVYVLIVTEVLE	NUDT3	91	O95989
HRTYVYVLTVTEILE	NUDT4	91	Q9NZJ9
YEKVHSIYNRLLAIE	CSTF3	356	Q12996
KISYVLVEFEVVYHT	DNAH8	556	Q96JB1
IVIELVKGYIHYVFD	NRXN2	966	Q9P2S2
IVHSYIAYKAAKEEE	PHF21A	551	Q96BD5
VVYVRDLGHVALYVV	SLC11A2	496	P49281
VVAQVLHYLYTSEIA	KLHL40	81	Q2TBA0
HRTYVYVLTVTELLE	NUDT11	91	Q96G61
DFIVVELVKGYLHYV	NRXN1	951	Q9ULB1
YINIVAYDHSRVKLA	PTPRZ1	1756	P23471
KIHEHETDTIYYKNI	PTPRQ	1321	Q9UMZ3
HIVEKFYNTLESIEY	PPP4R3C	621	Q6ZMV5
AVLTEYKLKAIEYVH	PROSER1	16	Q86XN7
DKYIYVADILAHEIH	PON2	231	Q15165
VVVKTHLYLLVATYT	PFN4	91	Q8NHR9
SQEIVAKYHTLYIDA	AWAT2	296	Q6E213
YEHKEIEYVETVTSR	BAIAP2L1	156	Q9UHR4
YEAVNEVYKVLIPIH	DOCK7	1791	Q96N67
AEYLEKHQIKEVVSY	EFCAB10	11	A6NFE3
QVHAAIKAFIAVYYL	CCNDBP1	91	O95273
LTYIDTKYVVHVKSL	IL23R	151	Q5VWK5
VVVTAEKIVHRYYSL	CPPED1	281	Q9BRF8
SEYVYEVVVDRKHVP	BLMH	416	Q13867
LYVKQEHAAYISEVE	INPP5B	431	P32019
INPYRAKEEYVVHTI	FLRT1	596	Q9NZU1
YKVVIIDEAHERSVY	DHX37	366	Q8IY37
VSEVIVLHYNYTGKL	S1PR5	11	Q9H228
AHVEDSDLIYKLYVV	LRRC8D	296	Q7L1W4
KHVIEFYEEILSLAY	IPO8	646	O15397
TYAVKDHVATIVYTV	OR1L8	266	Q8NGR8
THIYTAQDVKEVIEY	HEXA	231	P06865
IEYVESLKELHVFVA	SYTL2	636	Q9HCH5
EDYHLVYDIIQKVKE	SLC6A15	401	Q9H2J7
KVDYHVSLYIVAVLE	SOS2	121	Q07890
YIAELLAHKIHVYEK	PON1	236	P27169
TDIYDENLIYVILIH	SLC9C1	1041	Q4G0N8
VEILIEHYEKIFHTA	ARHGAP42	561	A6NI28
IICAIEYLHSKEIVY	PRKY	156	O43930
DQVTLLKYGVHEIIY	PPARG	341	P37231
YVETIIAKCIDHYTK	PSMD1	96	Q99460
LKQFDSVVHLIDYYV	SOCS2	116	O14508
VLVSTAKEVEHYKYE	SLFN11	811	Q7Z7L1
YETELVDIEKAIAHY	NAPA	131	P54920
IYEAIEKLIHLAETY	SLC4A8	606	Q2Y0W8
LVSVYELDYGKHELV	TDRD7	986	Q8NHU6
EVLGYKIDHQVSVYI	SOS1	116	Q07889
LVHIIYLATDYGTIK	SEMA5A	416	Q13591
YLIRLHNEIVYAVEK	RNF213	4886	Q63HN8
VVESEKLLKYDHYLV	TTC39B	611	Q5VTQ0
SEHIVYLLEVYRLAI	RLF	91	Q13129
VYHAIYLEELTAVEL	TFCP2	426	Q12800
YTLHAAVLQITKIIY	SLC25A46	396	Q96AG3
YIFITIILHAVVQEY	TRAM2	81	Q15035
TYHEVVDEIYFKVTH	PRPF38B	81	Q5VTL8
YETELVDIEKAIAHY	NAPB	131	Q9H115
VDLVQAKDTLYHVLY	SEMA5B	476	Q9P283
YYVVEEILEIRIHKL	PKD2	486	Q13563
IICAIEYLHSKEIVY	PRKX	156	P51817
GILLSIYAYHVEREK	VKORC1L1	26	Q8N0U8
KYVYFTIVTTDHKEI	PHLDA2	66	Q53GA4
LSHYQAALEYVEISK	TTC23	206	Q5W5X9
VHTYEQVIYTLQKAV	UBR2	236	Q8IWV8
LREYTQATIYVHKVV	USP48	856	Q86UV5
EGYLSVLHLKAVVYV	TFR2	491	Q9UP52
LYTLTHVVLLIYEAE	TMEM145	286	Q8NBT3
VYHTIYETFELVEKF	NAALAD2	541	Q9Y3Q0
HIISYLIEKSRVVYQ	MYO1H	181	Q8N1T3
KHEKIYTYVGSILIV	MYO9A	171	B2RTY4