Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoembryonic lethality during organogenesis, complete penetrance

SP2 EP400 RBL2 IFT172 DNM1L WNK1 F3 MET BPTF ARID2 KDR BICRAL ALAS2 TAF4 VCAM1

2.59e-067007315MP:0011098
MousePhenoembryonic lethality during organogenesis

SP2 EP400 RBL2 IFT172 DNM1L WNK1 F3 MET BPTF ARID2 KDR BICRAL ALAS2 TAF4 VCAM1

3.79e-058767315MP:0006207
DomainIg-like_fold

SEMA3C COL12A1 F3 PTK7 MET LRIG3 CD300LD IGHM CEACAM16 KDR SLAMF7 HCFC1 FCAMR VCAM1

1.13e-057069414IPR013783
DomainTAF4

TAF4 TAF4B

2.51e-052942PF05236
DomainTAF4

TAF4 TAF4B

2.51e-052942IPR007900
Domain-

SEMA3C COL12A1 F3 PTK7 MET LRIG3 CD300LD CEACAM16 KDR SLAMF7 HCFC1 FCAMR VCAM1

2.71e-0566394132.60.40.10
DomainIG_LIKE

SEMA3C PTK7 LRIG3 CD300LD IGHM CEACAM16 KDR SLAMF7 FCAMR VCAM1

1.81e-044919410PS50835
DomainIg-like_dom

SEMA3C PTK7 LRIG3 CD300LD IGHM CEACAM16 KDR SLAMF7 FCAMR VCAM1

2.19e-045039410IPR007110
DomainTAFH

TAF4 TAF4B

2.48e-045942SM00549
DomainTAFH_NHR1

TAF4 TAF4B

2.48e-045942IPR003894
DomainTAFH

TAF4 TAF4B

2.48e-045942PS51119
DomainTAFH

TAF4 TAF4B

2.48e-045942PF07531
DomainIG

SEMA3C PTK7 LRIG3 CD300LD CEACAM16 KDR SLAMF7 FCAMR VCAM1

2.70e-04421949SM00409
DomainIg_sub

SEMA3C PTK7 LRIG3 CD300LD CEACAM16 KDR SLAMF7 FCAMR VCAM1

2.70e-04421949IPR003599
DomainOSR1_C

WNK1 WNK3

3.71e-046942PF12202
DomainKinase_OSR1/WNK_CCT

WNK1 WNK3

3.71e-046942IPR024678
DomainSp1_fam

SP2 SP4

1.10e-0310942IPR030450
DomainGelsolin

VIL1 SEC24B

2.19e-0314942PF00626
DomainGelsolin-like_dom

VIL1 SEC24B

2.19e-0314942IPR007123
DomainV-set

CD300LD KDR SLAMF7 FCAMR VCAM1

2.38e-03184945PF07686
DomainIg_I-set

SEMA3C PTK7 LRIG3 KDR VCAM1

2.73e-03190945IPR013098
DomainI-set

SEMA3C PTK7 LRIG3 KDR VCAM1

2.73e-03190945PF07679
DomainLaminin_G

COL12A1 EYS FAT1

3.12e-0358943IPR001791
DomainIg_V-set

CD300LD KDR SLAMF7 FCAMR VCAM1

3.33e-03199945IPR013106
Domain-

NFYC TAF4 TAF4B

5.09e-03699431.10.20.10
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EP400 TTC28 SYNM LIN54 DNM1L ARCN1 TASOR2 MET LRIG3 FAT1 DENND6A CCDC88A USO1 SEC24B ZNF638 AKAP1 SPEN EPB41 TPI1

6.96e-13777991935844135
Pubmed

Human transcription factor protein interaction networks.

SP2 EP400 LIN54 SIX4 EMSY PHF21A BPTF FAT1 ARID2 SEC24B NFYC ZNF638 RACGAP1 PDCD11 TAF4 HERC2 R3HDM1 SPEN HCFC1 LRIF1 ILVBL

5.03e-101429992135140242
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SP2 PNKP EP400 LIN54 NOL11 SIX4 EMSY PHF21A BPTF ZNF638 RACGAP1 PDCD11 NUP188 TAF4 CDC27 SPEN HCFC1 LRIF1 ILVBL

3.87e-091294991930804502
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

EP400 TTC28 LIN54 NR3C1 ZCCHC2 WNK1 EMSY CCDC88A USO1 ARID2 MACF1 SPEN LRIF1

1.33e-08588991338580884
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

PNKP EP400 RBL2 LIN54 SIX4 NR3C1 EMSY PHF21A BPTF USO1 NFYC CDC27 SPEN HCFC1 NOVA2

2.09e-08857991525609649
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SEMA3C PNKP EP400 NOL11 SIX4 EMSY IQGAP1 AP1G1 ARID2 SEC24B PDCD11 MACF1 TAF4 HERC2 CDC27 AKAP1 SPEN ILVBL EPB41

3.97e-081497991931527615
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

EP400 LIN54 NOL11 EMSY PHF21A RACGAP1 PDCD11 SPEN HCFC1 LRIF1

4.90e-08339991030415952
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

EP400 TTC28 EMSY ARCN1 BPTF ARID2 SEC24B PDCD11 TAF4 SPEN HCFC1 EPB41

5.65e-08549991238280479
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EP400 DNM1L NR3C1 WNK1 EMSY ARCN1 PHF21A ARID2 SEC24B ZNF638 MACF1 AKAP1 HCFC1 EPB41 TPI1

6.43e-08934991533916271
Pubmed

Interaction network of human early embryonic transcription factors.

EP400 LIN54 SIX4 EMSY PHF21A BPTF ARID2 TAF4 SPEN LRIF1

6.78e-08351991038297188
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

EP400 TTC28 ADNP2 PHF21A BPTF LRIG3 FAT1 ARID2 MACF1 BICRAL NUP188 TAF4 TAF4B CDC27 ILVBL NOVA2

1.06e-071116991631753913
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

LIN54 ADNP2 EMSY BPTF ARID2 RACGAP1 TAF4 HERC2 CDC27 SPEN HCFC1 LRIF1

1.70e-07608991236089195
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

SP2 RC3H2 EP400 RBL2 ADNP2 SIX4 PHF21A ARID2 NFYC BICRAL

2.17e-07398991035016035
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RC3H2 SEMA3C TTC28 LAMB3 NR3C1 PTK7 CCDC88A AP1G1 ZNF638 RACGAP1 HCFC1 ILVBL

3.45e-07650991238777146
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

EP400 LIN54 NOL11 EMSY TASOR2 BPTF ARID2 ZNF638 RACGAP1 PDCD11 TAF4 SPEN HCFC1 EPB41

5.43e-07954991436373674
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

SP2 EP400 LIN54 NR3C1 EMSY PHF21A SEC24B TAF4 HCFC1 TPI1

5.89e-07444991034795231
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

SEMA3C COL12A1 DNM1L WNK1 MET BPTF FAT1 SEC24B RACGAP1 PDCD11 MACF1 NUP188 CDC27 AKAP1 HCFC1 ILVBL

7.83e-071297991633545068
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

TTC28 DNM1L THSD1 ARCN1 IQGAP1 CCDC88A USO1 SEC24B MACF1 CDC27 HCFC1 EPB41

8.49e-07708991239231216
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

SYNM EMSY IQGAP1 MET BPTF USO1 SEC24B ZNF638 MACF1

9.42e-0736099933111431
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EP400 NOL11 ARCN1 IQGAP1 BPTF ZNF638 CKAP2L RACGAP1 PDCD11 MACF1 NUP188 HERC2 SPEN TPI1

1.25e-061024991424711643
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NOL11 TASOR2 IQGAP1 BPTF ZNF638 PDCD11 MACF1 NUP188 HERC2 SPEN HCFC1

2.66e-06653991122586326
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

SP4 EP400 LIN54 EMSY PHF21A IQGAP1 BPTF ARID2 BICRAL TAF4 SPEN HCFC1 LRIF1 TPI1

2.97e-061103991434189442
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

EP400 LIN54 SIX4 BPTF SPEN

4.11e-068399528794006
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

WNK1 FCGBP RAB2B HERC2 FCAMR

4.36e-068499515203218
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

EP400 ADNP2 PHF21A BPTF TAF4 HCFC1

4.69e-0615099628242625
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TTC28 DNM1L WNK1 CCDC88A USO1 SEC24B RACGAP1 MACF1 R3HDM1 AKAP1 EPB41 WNK3

6.32e-06861991236931259
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

LIN54 NR3C1 WNK1 EMSY ARCN1 IQGAP1 FCGBP AP1G1 USO1 PDCD11 CDC27 HCFC1 ILVBL EPB41 TPI1

7.43e-061367991532687490
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

VIL1 RC3H2 EP400 NOL11 ARCN1 IQGAP1 ANKRD36B USO1 RAB2B CKAP2L RACGAP1 PDCD11 HERC2 HCFC1 TPI1

7.69e-061371991536244648
Pubmed

IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.

IQGAP1 KDR

8.02e-06299215217908
Pubmed

Anlotinib, a novel small molecular tyrosine kinase inhibitor, suppresses growth and metastasis via dual blockade of VEGFR2 and MET in osteosarcoma.

MET KDR

8.02e-06299230719715
Pubmed

Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cells.

DNM1L AKAP1

8.02e-06299232312949
Pubmed

The role of c-Met and VEGFR2 in glioblastoma resistance to bevacizumab.

MET KDR

8.02e-06299233727583
Pubmed

c-Met activation in medulloblastoma induces tissue factor expression and activity: effects on cell migration.

F3 MET

8.02e-06299219359592
Pubmed

Regulation of Na+-K+-Cl- cotransporter type 2 by the with no lysine kinase-dependent signaling pathway.

WNK1 WNK3

8.02e-06299230917032
Pubmed

AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission.

DNM1L AKAP1

8.02e-06299230093535
Pubmed

Biphasic effect of PTK7 on KDR activity in endothelial cells and angiogenesis.

PTK7 KDR

8.02e-06299225986862
Pubmed

Phase II and Biomarker Study of Cabozantinib in Metastatic Triple-Negative Breast Cancer Patients.

MET KDR

8.02e-06299227789775
Pubmed

Structural changes in TAF4b-TFIID correlate with promoter selectivity.

TAF4 TAF4B

8.02e-06299218206971
Pubmed

AKAP1 Regulates Mitochondrial Dynamics during the Fatty-Acid-Promoted Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes as Indicated by Proteomics Sequencing.

DNM1L AKAP1

8.02e-06299237175819
Pubmed

FcGBP and VCAM-1 are ponderable biomarkers for differential diagnosis of alcoholic liver cirrhosis.

FCGBP VCAM1

8.02e-06299235245761
Pubmed

Protein 4.1R regulates cell migration and IQGAP1 recruitment to the leading edge.

IQGAP1 EPB41

8.02e-06299221750196
Pubmed

A novel inhibitor of c-Met and VEGF receptor tyrosine kinases with a broad spectrum of in vivo antitumor activities.

MET KDR

8.02e-06299223548264
Pubmed

Microparticle-associated vascular adhesion molecule-1 and tissue factor follow a circadian rhythm in healthy human subjects.

F3 VCAM1

8.02e-06299218449421
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RC3H2 EP400 TTC28 TASOR2 BPTF ZNF638 TTC5 SPEN HCFC1

8.09e-0646999927634302
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

EP400 SIX4 BPTF AP1G1 ARID2 CKAP2L RACGAP1 MACF1 EPB41

8.51e-0647299938943005
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

PNKP EP400 EMSY BPTF TAF4 HCFC1

8.68e-0616799620362541
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

TTC28 SYNM CCDC88A SEC24B ZNF638 MACF1 R3HDM1

1.07e-0526399734702444
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

NOL11 ARCN1 IQGAP1 BPTF ARID2 CKAP2L RACGAP1 PDCD11 MACF1 HERC2 AKAP1

1.10e-05759991135915203
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

SP2 DNM1L NR3C1 ARCN1 IQGAP1 BPTF USO1 ZNF638

1.12e-0537099822922362
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

PNKP EP400 PHF21A BPTF CDC27 HCFC1

1.21e-0517799626206133
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

EP400 NOL11 EMSY BPTF ZNF638 SPEN HCFC1

1.72e-0528399730585729
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EP400 TTC28 IFT172 TENM2 LRIG3 MACF1 R3HDM1 SPEN

2.22e-0540799812693553
Pubmed

TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3.

TAF4 TAF4B

2.40e-05399224498316
Pubmed

The P2Y2 nucleotide receptor mediates vascular cell adhesion molecule-1 expression through interaction with VEGF receptor-2 (KDR/Flk-1).

KDR VCAM1

2.40e-05399215175347
Pubmed

IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis.

IQGAP1 KDR

2.40e-05399219050761
Pubmed

SIX4 promotes hepatocellular carcinoma metastasis through upregulating YAP1 and c-MET.

SIX4 MET

2.40e-05399233046796
Pubmed

MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation.

MET KDR

2.40e-05399226137585
Pubmed

IQGAP1 causes choroidal neovascularization by sustaining VEGFR2-mediated Rac1 activation.

IQGAP1 KDR

2.40e-05399232783108
Pubmed

O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities.

SP2 SP4

2.40e-05399226431879
Pubmed

Dual inhibition using cabozantinib overcomes HGF/MET signaling mediated resistance to pan-VEGFR inhibition in orthotopic and metastatic neuroblastoma tumors.

MET KDR

2.40e-05399227922668
Pubmed

Dependence on phosphoinositide 3-kinase and RAS-RAF pathways drive the activity of RAF265, a novel RAF/VEGFR2 inhibitor, and RAD001 (Everolimus) in combination.

PIK3CG KDR

2.40e-05399220124452
Pubmed

A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis.

MET KDR

2.40e-05399219773544
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

XIRP1 COL12A1 ADNP2 DNM1L TUT1 FAT1 CKAP2L TAF4 TAF4B LRIF1

2.79e-05689991036543142
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

LIN54 EMSY PHF21A CCDC88A HCFC1

2.80e-0512399526912792
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

EMSY BPTF TAF4 TAF4B LRIF1

2.91e-0512499520850016
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

TTC28 TUT1 KRT79 ARCN1 IQGAP1 PIK3CG IGHM NUP188 HERC2 CDC27 AKAP1 HCFC1

2.92e-051005991219615732
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EP400 ADNP2 NOL11 ARCN1 IQGAP1 AP1G1 SEC24B ZNF638 RACGAP1 PDCD11 MACF1 HERC2 CDC27 TPI1

2.95e-051353991429467282
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

EP400 EMSY RACGAP1 PDCD11 HCFC1 LRIF1

4.32e-0522299637071664
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

EP400 TTC28 WNK1 CCDC88A USO1 ZNF638 RACGAP1 R3HDM1 AKAP1 HCFC1

4.69e-05733991034672954
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

EP400 DNM1L IQGAP1 BPTF ARID2 ZNF638 HCFC1

4.76e-0533299732786267
Pubmed

Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia.

DNM1L AKAP1

4.79e-05499222099302
Pubmed

Human urotensin II induces tissue factor and cellular adhesion molecules expression in human coronary endothelial cells: an emerging role for urotensin II in cardiovascular disease.

F3 VCAM1

4.79e-05499218284603
Pubmed

WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.

WNK1 WNK3

4.79e-05499211571656
Pubmed

Localization of alpha 4m integrin at sites of mesenchyme condensation during embryonic mouse development.

VCAM1 TPI1

4.79e-0549928522070
Pubmed

Human hypertension caused by mutations in WNK kinases.

WNK1 WNK3

4.79e-05499211498583
Pubmed

Vascular endothelial growth factor receptor-2 expression is induced by 17beta-estradiol in ZR-75 breast cancer cells by estrogen receptor alpha/Sp proteins.

SP4 KDR

4.79e-05499216574784
Pubmed

TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.

TAF4 TAF4B

4.79e-05499219635797
Pubmed

Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion.

KDR VCAM1

4.79e-05499211784053
Pubmed

SLC26A9 is a Cl(-) channel regulated by the WNK kinases.

WNK1 WNK3

4.79e-05499217673510
Pubmed

Coordinated deregulation of cellular receptors, proangiogenic factors and intracellular pathways in acute myeloid leukaemia.

F3 KDR

4.79e-05499217577783
Pubmed

sIgM-FcμR Interactions Regulate Early B Cell Activation and Plasma Cell Development after Influenza Virus Infection.

IGHM FCAMR

4.79e-05499228747342
Pubmed

Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.

WNK1 WNK3

4.79e-05499234384519
Pubmed

p110δ phosphoinositide 3-kinase represses IgE switch by potentiating BCL6 expression.

PIK3CG IGHM

4.79e-05499222422878
Pubmed

Regulation of expression of the chorionic gonadotropin/luteinizing hormone receptor gene in the human myometrium: involvement of specificity protein-1 (Sp1), Sp3, Sp4, Sp-like proteins, and histone deacetylases.

SP2 SP4

4.79e-05499215788387
Pubmed

Regulation of glucocorticoid receptor activity by a stress responsive transcriptional cofactor.

NR3C1 TTC5

4.79e-05499221147850
Pubmed

Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer.

MET KDR

4.79e-05499228973887
Pubmed

VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex.

MET KDR

4.79e-05499222789536
Pubmed

Sp2 is the only glutamine-rich specificity protein with minor impact on development and differentiation in myelinating glia.

SP2 SP4

4.79e-05499227889927
Pubmed

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2.

PTK7 KDR

4.79e-05499214977921
Pubmed

LIN54 is an essential core subunit of the DREAM/LINC complex that binds to the cdc2 promoter in a sequence-specific manner.

RBL2 LIN54

4.79e-05499219725879
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

EP400 EMSY BPTF ZNF638 NUP188 SPEN HCFC1

5.63e-0534199732971831
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SEMA3C SYNM NOL11 LAMB3 KRT79 ARCN1 TASOR2 IQGAP1 ZNF638 RACGAP1 PDCD11 SPEN TPI1

5.85e-051257991336526897
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

VIL1 LIN54 KRT79 TASOR2 IQGAP1 PTK7 BPTF FAM186A MACF1 KDR ALAS2 TAF4 CDC27 SPEN

5.87e-051442991435575683
Pubmed

A human MAP kinase interactome.

ADNP2 WNK1 CCDC88A ARID2 NFYC MACF1 BICRAL HERC2

7.73e-0548699820936779
Pubmed

Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter.

SP2 SP4

7.98e-05599210547281
Pubmed

Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.

WNK1 WNK3

7.98e-05599224641320
Pubmed

Systematic molecular genetic analysis of congenital sideroblastic anemia: evidence for genetic heterogeneity and identification of novel mutations.

SLC19A2 ALAS2

7.98e-05599219731322
Pubmed

The Allantoic Core Domain: new insights into development of the murine allantois and its relation to the primitive streak.

VIL1 KDR

7.98e-05599219191225
Pubmed

Brachyury is required for elongation and vasculogenesis in the murine allantois.

KDR VCAM1

7.98e-05599216835439
Pubmed

Targeted disruption of heparan sulfate interaction with hepatocyte and vascular endothelial growth factors blocks normal and oncogenic signaling.

MET KDR

7.98e-05599222897854
InteractionNFYC interactions

SP2 SP4 EP400 LIN54 ADNP2 EMSY ARID2 NFYC BICRAL TAF4

1.38e-081779710int:NFYC
InteractionELF4 interactions

SP2 EP400 LIN54 EMSY BPTF ARID2 TAF4 LRIF1

8.33e-08115978int:ELF4
InteractionELF1 interactions

EP400 LIN54 EMSY BPTF ARID2 NFYC TAF4 LRIF1

1.69e-07126978int:ELF1
InteractionFHL2 interactions

SP2 SP4 EP400 WNK1 EMSY PHF21A IQGAP1 NFYC ZNF638 SPEN LRIF1 WNK3

4.45e-073969712int:FHL2
InteractionFEV interactions

SP2 EP400 LIN54 SIX4 EMSY PHF21A ARID2 TAF4

6.20e-06203978int:FEV
InteractionNUP43 interactions

EP400 LIN54 NOL11 EMSY PHF21A TASOR2 BPTF CCDC88A ARID2 PDCD11 TAF4 SPEN HCFC1

9.26e-066259713int:NUP43
InteractionTERF2IP interactions

EP400 LIN54 NOL11 EMSY TASOR2 BPTF ZNF638 RACGAP1 TAF4 SPEN HCFC1 LRIF1

1.36e-055529712int:TERF2IP
InteractionNFIX interactions

EP400 LIN54 SIX4 EMSY BPTF ARID2 TAF4 SPEN

1.40e-05227978int:NFIX
InteractionKLF3 interactions

EP400 LIN54 EMSY PHF21A BPTF ARID2 TAF4 LRIF1

1.44e-05228978int:KLF3
InteractionELK3 interactions

SP2 SP4 EP400 LIN54 EMSY TAF4

2.50e-05120976int:ELK3
InteractionASF1A interactions

EP400 LIN54 EMSY TASOR2 ARID2 SPEN HCFC1 LRIF1

2.72e-05249978int:ASF1A
InteractionMAD2L1 interactions

LIN54 ADNP2 NOL11 BPTF FAT1 CCDC88A MACF1 CDC27

2.96e-05252978int:MAD2L1
InteractionKLF8 interactions

EP400 LIN54 EMSY PHF21A BPTF ARID2 ZNF638 TAF4 SPEN

2.99e-05329979int:KLF8
InteractionFBXO42 interactions

EP400 TTC28 NR3C1 WNK1 CCDC88A USO1 ARID2 MACF1

3.60e-05259978int:FBXO42
InteractionWWTR1 interactions

EP400 TTC28 EMSY ARCN1 BPTF ARID2 SEC24B PDCD11 HCFC1 EPB41

3.62e-054229710int:WWTR1
InteractionBRD2 interactions

RBL2 ADNP2 BPTF ARID2 RAB2B BICRAL TAF4 TAF4B CDC27 NOVA2

4.15e-054299710int:BRD2
InteractionFOXP3 interactions

SP2 DNM1L NR3C1 ARCN1 IQGAP1 BPTF USO1 ZNF638 CDC27 NOVA2

4.41e-054329710int:FOXP3
InteractionCLTA interactions

NR3C1 WNK1 IQGAP1 AP1G1 USO1 SEC24B HERC2 WNK3 VCAM1

4.95e-05351979int:CLTA
InteractionEED interactions

PNKP EP400 NOL11 DNM1L ARCN1 TASOR2 IQGAP1 BPTF AP1G1 USO1 SEC24B ZNF638 PDCD11 MACF1 NUP188 HERC2 SPEN HCFC1 TPI1

5.10e-0514459719int:EED
InteractionSRF interactions

SP2 ADNP2 SIX4 BPTF ARID2 NFYC

5.71e-05139976int:SRF
InteractionNAA40 interactions

EP400 DNM1L NR3C1 WNK1 EMSY ARCN1 PHF21A ARID2 SEC24B ZNF638 MACF1 AKAP1 HCFC1 EPB41 TPI1

6.50e-059789715int:NAA40
InteractionSP1 interactions

SP2 SP4 NR3C1 FAT1 NFYC TAF4 SPEN HCFC1 TPI1

6.68e-05365979int:SP1
InteractionKLF15 interactions

SP2 EP400 LIN54 EMSY ARID2 NFYC ZNF638 TAF4

7.97e-05290978int:KLF15
InteractionCEBPA interactions

SP4 EP400 LIN54 NR3C1 EMSY PHF21A IQGAP1 BPTF ARID2 PDCD11 MACF1 BICRAL TAF4 SPEN HCFC1 LRIF1 TPI1

8.52e-0512459717int:CEBPA
InteractionPPIA interactions

EP400 DNM1L SIX4 ANKRD36C BPTF AP1G1 ARID2 CKAP2L RACGAP1 MACF1 ANKRD36 HCFC1 EPB41 VCAM1

8.73e-058889714int:PPIA
InteractionSQSTM1 interactions

SEMA3C PNKP TTC28 IFT172 DNM1L ZCCHC2 WNK1 PHF21A IQGAP1 BPTF SEC24B RAB2B RACGAP1 KDR NUP188 CDC27 TPI1

9.58e-0512579717int:SQSTM1
InteractionTAF4 interactions

PNKP NFYC TAF4 HERC2 CDC27 HCFC1

1.08e-04156976int:TAF4
InteractionVCL interactions

RC3H2 HTRA4 WNK1 USO1 MACF1 KDR VCAM1 TPI1

1.13e-04305978int:VCL
InteractionTFCP2L1 interactions

PNKP EP400 EMSY BPTF HCFC1

1.16e-0499975int:TFCP2L1
InteractionSOX2 interactions

SP2 SEMA3C EP400 LIN54 NOL11 DNM1L TUT1 SIX4 IQGAP1 BPTF ARID2 IGHM ZNF638 CKAP2L PDCD11 MACF1 SPEN TPI1

1.35e-0414229718int:SOX2
InteractionXRCC6 interactions

RC3H2 PNKP EP400 LIN54 NOL11 DNM1L EMSY BPTF NFYC ZNF638 SPEN HCFC1 ILVBL VCAM1

1.39e-049289714int:XRCC6
InteractionGTF2A1 interactions

SP2 SP4 HTRA4 TAF4 TAF4B

1.47e-04104975int:GTF2A1
InteractionTTC28 interactions

TTC28 NR3C1 HTRA4 PHF21A PDCD11

1.75e-04108975int:TTC28
InteractionEGR2 interactions

EP400 SIX4 EMSY PHF21A ARID2 HCFC1

1.78e-04171976int:EGR2
InteractionPHF12 interactions

NR3C1 EMSY PHF21A BPTF NFYC

1.91e-04110975int:PHF12
InteractionBAG2 interactions

RC3H2 LAMB3 NR3C1 WNK1 PTK7 BPTF NFYC R3HDM1 AKAP1 SPEN WNK3

1.99e-046229711int:BAG2
InteractionANKRD36B interactions

ANKRD36C NR3C1 ANKRD36B SPEN

2.00e-0460974int:ANKRD36B
InteractionRAD51AP2 interactions

NR3C1 ZNF638

2.27e-045972int:RAD51AP2
InteractionSNRNP40 interactions

RC3H2 EP400 ADNP2 NOL11 EMSY PHF21A TASOR2 ARID2 PDCD11 TAF4 SPEN

2.44e-046379711int:SNRNP40
InteractionH3-3A interactions

LIN54 ADNP2 EMSY BPTF ARID2 RACGAP1 TAF4 HERC2 CDC27 SPEN HCFC1 LRIF1

2.51e-047499712int:H3-3A
InteractionKCNA3 interactions

TTC28 DNM1L THSD1 ARCN1 IQGAP1 CCDC88A USO1 SEC24B MACF1 CDC27 SPEN HCFC1 EPB41

2.72e-048719713int:KCNA3
InteractionYWHAQ interactions

PNKP TTC28 DNM1L TUT1 WNK1 IQGAP1 CCDC88A USO1 IGHM ZNF638 RACGAP1 MACF1 R3HDM1 EPB41 TPI1

2.83e-0411189715int:YWHAQ
InteractionLBX1 interactions

RBL2 IQGAP1 WNK3

2.91e-0427973int:LBX1
InteractionPOGZ interactions

SP4 ADNP2 NR3C1 ANKRD36B NFYC KDR LRIF1

2.95e-04265977int:POGZ
InteractionETS1 interactions

EP400 NR3C1 EMSY BPTF ARID2

2.98e-04121975int:ETS1
InteractionSMC5 interactions

EP400 LIN54 NOL11 EMSY TASOR2 BPTF ARID2 ZNF638 RACGAP1 PDCD11 TAF4 SPEN HCFC1 EPB41

3.00e-0410009714int:SMC5
InteractionYY1 interactions

EP400 LIN54 EMSY BPTF ARID2 ZNF638 TAF4 HCFC1 LRIF1

3.42e-04454979int:YY1
InteractionHNF4A interactions

EP400 LIN54 EMSY BPTF ARID2 TAF4 SPEN

3.68e-04275977int:HNF4A
InteractionBANP interactions

SP2 SP4 LIN54 PHF21A BICRAL ALAS2 LRIF1

3.85e-04277977int:BANP
InteractionCIC interactions

EP400 LIN54 SIX4 NR3C1 PHF21A ARHGAP22 NFYC PDCD11 TAF4 HCFC1 EPB41

3.90e-046739711int:CIC
InteractionR3HDM2 interactions

RC3H2 ZCCHC2 SEC24B R3HDM1 AKAP1

4.00e-04129975int:R3HDM2
InteractionTNRC6A interactions

RC3H2 SYNM WNK1 PHF21A SEC24B CDC27 AKAP1

4.10e-04280977int:TNRC6A
InteractionE2F1 interactions

SP2 SP4 RBL2 EMSY CDC27 HCFC1

4.14e-04200976int:E2F1
InteractionH2AZ1 interactions

RC3H2 EP400 EMSY BPTF ARID2 TAF4 CDC27 HCFC1

4.25e-04371978int:H2AZ1
InteractionPLXND1 interactions

SEMA3C MACF1 KDR

4.41e-0431973int:PLXND1
InteractionNHLRC2 interactions

DNM1L KRT79 ARCN1 IQGAP1 AP1G1 MACF1 HERC2 TPI1

4.56e-04375978int:NHLRC2
Cytoband1p32-p31

MACF1 VCAM1

1.64e-0499921p32-p31
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SEMA3C PTK7 LRIG3 KDR VCAM1

2.26e-04161625593
GeneFamilyAdenosine receptors|V-set domain containing

CD300LD CEACAM16 KDR SLAMF7 FCAMR

2.39e-04163625590
GeneFamilyReceptor Tyrosine Kinases|CD molecules

PTK7 MET KDR

3.47e-0440623321
GeneFamilyZinc fingers C2H2-type|Sp transcription factors

SP2 SP4

4.10e-049622755
GeneFamilyImmunoglobulin like domain containing

PTK7 CEACAM16 KDR VCAM1

4.33e-03193624594
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

SYNM AKAP1

4.43e-0329622396
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

SEMA3C NR3C1 F3 PHF21A BPTF FAT1 SEC24B NFYC ZNF638 TAF4 R3HDM1 CDC27 SPEN

2.05e-084669813M13522
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SEMA3C TTC28 NR3C1 F3 PHF21A BPTF FAT1 SEC24B NFYC ZNF638 MACF1 BICRAL TAF4 R3HDM1 CDC27 SPEN

1.13e-078569816M4500
CoexpressionGSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_DN

GPM6B LIN54 SLC19A2 CCDC88A ARID2 R3HDM1 LRIF1

1.04e-05200987M9777
CoexpressionGSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN

DNM1L TUT1 F3 USO1 SEC24B CDC27 VCAM1

1.04e-05200987M9848
CoexpressionCARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_HYPOMETHYLATED_AND_UP

SEMA3C COL12A1 PTK7 CKAP2L RACGAP1 R3HDM1

3.34e-05162986M45037
CoexpressionPLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP

GPM6B SEMA3C F3 VCAM1

6.23e-0557984MM948
CoexpressionPLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP

GPM6B SEMA3C F3 VCAM1

6.68e-0558984M2452
CoexpressionGSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN

RC3H2 ZNF407 BPTF DENND6A SEC24B RAB2B

9.90e-05197986M8464
CoexpressionGSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN

GPM6B ANKRD36B CCDC88A PIK3CG IGHM ANKRD36

1.05e-04199986M4964
CoexpressionGSE20715_WT_VS_TLR4_KO_LUNG_DN

EMSY CCDC88A IGHM NFYC SPEN VCAM1

1.05e-04199986M4350
CoexpressionGSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP

LIN54 TCEANC2 CKAP2L RACGAP1 SPEN VCAM1

1.08e-04200986M8085
CoexpressionGSE19512_NAUTRAL_VS_INDUCED_TREG_DN

NR3C1 F3 MET ALAS2 R3HDM1 NOVA2

1.08e-04200986M8359
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ZNF407 ANKRD36C TASOR2 AP1G1 ARID2 MACF1 ANKRD36 SPEN

9.90e-09188998ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

ANKRD36C KRT79 ANKRD36B IGHM MACF1 ANKRD36

1.35e-06156996afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PNKP FAM78B TAF4B HERC2 VCAM1 NOVA2

2.01e-06167996774f3264318b002d0df5d06d41d645366038d0bf
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ANKRD36C ANKRD36B AP1G1 ARID2 MACF1 ANKRD36

3.21e-06181996f2315414e714ac86211546a935660c4be6e85f1b
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR3C1 IQGAP1 CCDC88A ZNF638 MACF1 SLAMF7

3.31e-06182996f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR3C1 IQGAP1 CCDC88A ZNF638 MACF1 SLAMF7

3.64e-061859967adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM63C LAMB3 F3 FAT1 FCGBP VCAM1

4.11e-06189996319e42f6e2322208de78bc666fb2c074707eb4da
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

THSD1 MET EYS PIK3CG KDR NOVA2

4.24e-061909961307688255a1250fa300edf2c41f1affe31dcc98
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

TTC28 WNK1 BPTF LRIG3 ARID2 ZNF638

4.50e-06192996916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ANKRD36C ANKRD36B BPTF ZNF638 ANKRD36 EPB41

4.92e-06195996d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RBL2 ANKRD36C IGHM MACF1 ANKRD36 EPB41

5.22e-06197996c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

SEMA3C TTC28 ANKRD36C BPTF CCDC88A ANKRD36

5.37e-06198996de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF407 ANKRD36C BPTF MACF1 ANKRD36 EPB41

5.53e-06199996f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3|TCGA-Brain / Sample_Type by Project: Shred V9

RC3H2 TASOR2 EYS SPEN EPB41

1.29e-05135995b128596653a5e3b64ed7f657bbfeda35438e2e48
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8|TCGA-Bladder / Sample_Type by Project: Shred V9

SLC19A2 ZNF799 TAF4 ZNF443 EPB41

2.14e-051509951aa9320d97ff10994ea024751790524fe133aba9
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

ANKRD36C ANKRD36B MACF1 ANKRD36 EPB41

2.21e-05151995999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C FAM78B FAT1 CEACAM16 RAB2B

2.43e-0515499537765512dfae557b9f6eb30a29463b93682a4404
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B DENND6A CD300LD PIK3CG TTC5

2.43e-0515499566c93733116e31b65dfb4b0b00de5c39d19cdb84
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RBL2 FCGBP IGHM MACF1 BICRAL

2.83e-051599952881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC19A2 ZNF407 ZNF441 ZNF799 HERC2

3.01e-051619955fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIN54 SIX4 SEC24B TAF4B SLAMF7

3.48e-05166995de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCellCOVID-19-Heart-Adipocyte|Heart / Disease (COVID-19 only), tissue and cell type

GPM6B SEMA3C SLC19A2 LAMB3 F3

3.79e-05169995bd39f85b48207955f80ca120a11e15a0124117b9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

GPM6B SIX4 MET LRIG3 FAT1

3.90e-05170995269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

VIL1 SEMA3C HTRA4 ARHGAP22 CCDC88A

3.90e-051709953a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMB3 WNK1 F3 ARHGAP22 MACF1

4.60e-05176995f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B WNK1 CD300LD TCEANC2 VCAM1

4.60e-051769958e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

THSD1 EYS PIK3CG KDR NOVA2

4.85e-05178995c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTRA4 F3 FAT1 CEACAM16 VCAM1

5.25e-0518199535eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTRA4 F3 FAT1 CEACAM16 VCAM1

5.25e-05181995e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

LAMB3 F3 MET LRIG3 FAT1

5.53e-051839950f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR3C1 IQGAP1 CCDC88A ZNF638 MACF1

5.68e-051849951154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88A PIK3CG IGHM ANKRD36 SLAMF7

5.82e-05185995ff598af88c7f9d7224cc4ed96b1c3463ef76b550
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88A PIK3CG IGHM ANKRD36 SLAMF7

5.98e-05186995b9fb7210f615faff0633a1c82dd3be38cb72a00b
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ANKRD36C ARID2 MACF1 SPEN VCAM1

5.98e-051869958571956890fc9894d766ba294a28e376b4aba428
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PNKP LAMB3 MET RACGAP1 SLAMF7

6.13e-05187995a6a112689d1c9049f57935ad9d2f4955538427de
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB3 SIX4 F3 MET FAT1

6.44e-05189995783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB3 SIX4 F3 MET FAT1

6.44e-0518999588b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB3 SIX4 F3 MET FAT1

6.61e-0519099547e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB3 SIX4 F3 MET FAT1

6.61e-05190995261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

LAMB3 F3 MET LRIG3 FAT1

6.61e-05190995ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ANKRD36C IQGAP1 ARID2 MACF1 SPEN

6.77e-051919959454f642c3621370fa23640b631301346b300950
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB3 THSD1 TENM2 LRIG3 FCGBP

6.77e-05191995ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

THSD1 EYS PIK3CG KDR NOVA2

6.77e-05191995e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

ANKRD36C BPTF CCDC88A PDCD11 ANKRD36

6.94e-051929959cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ANKRD36C ANKRD36B AP1G1 MACF1 ANKRD36

6.94e-0519299547646d7e4990be85072987f92bf18d52f8da752e
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

LAMB3 F3 MET LRIG3 FAT1

6.94e-051929959b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

TTC28 WNK1 BPTF ARID2 ZNF638

7.11e-05193995e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

WNK1 FCGBP SLAMF7 EPB41 VCAM1

7.29e-05194995b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNM DENND6A KDR VCAM1 NOVA2

7.47e-051959956a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3C ZCCHC2 HTRA4 ARHGAP22 CCDC88A

7.47e-051959959d649ac7d2af313481069c95349efc0c68449e2b
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RBL2 ANKRD36C MACF1 ANKRD36 EPB41

7.47e-051959954bdedd924564a260841a9153604026b57487c83d
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB3 F3 TENM2 MET FAT1

7.65e-05196995c5adab88140a465698abcbedc6505a43cae7bfd1
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB3 NR3C1 THSD1 TENM2 MACF1

7.65e-05196995c936014125b2ed5f796221b74acb77b8f8359875
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

RC3H2 WNK1 PTK7 PIK3CG SLAMF7

7.65e-0519699509d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA3C SYNM LAMB3 MET FAT1

7.84e-05197995f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell(2)_Fibroblasts-(24)_Fibro-5|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

GPM6B SEMA3C COL12A1 SYNM WNK1

7.84e-0519799583a4b79fbfa1cf63441dee4424c3b87c988287bf
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB3 ANKRD36C F3 MET FAT1

8.03e-0519899577517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARHGAP22 CCDC88A CD300LD PIK3CG SLAMF7

8.03e-05198995b2c8d5956f8449df4b69fb1b30632253440f815e
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C LAMB3 ARCN1 IQGAP1 PTK7

8.22e-051999958d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellhealthy_donor-Lymphocytic|healthy_donor / Disease condition, Lineage, Cell class and subclass

RBL2 MACF1 ANKRD36 SLAMF7 EPB41

8.22e-051999952841e16d54acd344ba454f024e285c28abc37319
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

ADNP2 WNK1 BPTF FAT1 HCFC1

8.22e-05199995358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ANKRD36C ANKRD36B FCGBP KDR ANKRD36

8.41e-05200995292c63693eb7f435335a8cfba07aa35b72139393
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

GPM6B TENM2 ZNF441 ANKRD36 WNK3

8.41e-05200995ac0e023dbb383bbc46c5cc525431778be8f7ef46
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

GPM6B TTC28 PHF21A PTK7 MACF1

8.41e-05200995a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellCOVID-19|World / Disease, condition lineage and cell class

ZCCHC2 IQGAP1 BPTF MACF1 EPB41

8.41e-052009957dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Astrocyte|GW23 / Sample Type, Dataset, Time_group, and Cell type.

GPM6B THSD1 F3 FAT1 VCAM1

8.41e-052009954fe3b2d80c567c18621bff3341f9a73578c81621
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB3 F3 MET LRIG3 FAT1

8.41e-052009950594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

ANKRD36C MACF1 ANKRD36 EPB41

1.54e-0412199419333a660800b583fa27b495c1f7828e6636a257
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3C KRT79 F3 FAT1

1.69e-0412499436dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3C KRT79 F3 FAT1

2.62e-041399949e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellLPS_only-Myeloid-Dendritic_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP22 CCDC88A PIK3CG SLAMF7

3.32e-04148994cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

SIX4 TASOR2 SPEN EPB41

3.41e-04149994768877bade04ca0321593b8470b5011ad8270431
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

MET LRIG3 FAT1 TAF4B

3.49e-04150994b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

SIX4 ZCCHC2 LRIG3 NOVA2

3.67e-041529942ff0980dfd8d430cca14649151d856edef115720
ToppCellBronchial_Biopsy-Epithelial-Goblet_2|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ANKRD36C ANKRD36B PIK3CG KDR

3.77e-04153994b25629953ff79aff645845376132b12023067b01
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RBL2 LIN54 AP1G1 SPEN

3.77e-04153994553dff9688a1996d8f4ba16e60c683593d781389
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RBL2 LIN54 AP1G1 SPEN

3.77e-0415399488ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM78B IQGAP1 CD300LD SLAMF7

3.86e-041549941e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C RBL2 FAM78B RAB2B

3.96e-04155994c58a5fb8d853f12204e961d633e83452eb12a659
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C RBL2 FAM78B RAB2B

3.96e-041559949cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

GPM6B MET FAT1 FCGBP

4.15e-0415799431d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HTRA4 ARHGAP22 ZNF799 BICRAL

4.15e-04157994a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP2 SLC19A2 CD300LD ALAS2

4.25e-04158994b0508a600994090c6aafd8d779437190a33ad821
ToppCellfacs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP2 SLC19A2 CD300LD ALAS2

4.25e-04158994a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM63C PIK3CG FAM186A SLAMF7

4.25e-041589946b51e5ee08e23924f5edbaf0a845a9232fb7ff7a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM63C PIK3CG FAM186A SLAMF7

4.25e-041589948dd83a2a4c2ec9cdc3a03df8b51ee22bee1c2888
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

GPM6B PTK7 ALAS2 VCAM1

4.35e-04159994b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ANKRD36C F3 FCGBP KDR

4.57e-04161994bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellfacs-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 CCDC88A CD300LD VCAM1

4.57e-0416199445591addc765760db6029ac19e80573373d1d917
ToppCellfacs-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 CCDC88A CD300LD VCAM1

4.57e-041619948741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCellfacs-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 CCDC88A CD300LD VCAM1

4.57e-041619949cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

VIL1 SYNM RACGAP1 ZNF443

4.67e-04162994a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

ANKRD36C ANKRD36B MACF1 EPB41

4.67e-04162994b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRMT10B IGHM BICRAL SLAMF7

5.01e-0416599466f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 SLC19A2 KDR VCAM1

5.01e-041659946d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 SLC19A2 KDR VCAM1

5.01e-0416599484f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

PTK7 ARHGAP22 FAT1 CKAP2L

5.12e-041669949788486582cc2c5f28b9ea015e235732f9fefb1e
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Liver / Manually curated celltypes from each tissue

EMSY ARCN1 TAF4B R3HDM1

5.12e-041669949afa33b5ad27dc33576be592f9b22d8161366838
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 CD300LD PIK3CG SLAMF7

5.24e-04167994991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCellfacs-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 CD300LD PIK3CG SLAMF7

5.24e-04167994f22d1471c785b30d096ec5cdc68974e850ed7de0
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

COL12A1 ANKRD36C BPTF FAT1 ZNF638 MACF1 SPEN

6.75e-0950577GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

TASOR2 ZNF638 MACF1 SPEN

1.36e-0450574GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
DrugEtifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A

RC3H2 RBL2 WNK1 IQGAP1 MET BPTF CCDC88A USO1 CDC27 SPEN

4.63e-0917897103998_DN
DrugNeostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

RC3H2 RBL2 IQGAP1 MET BPTF USO1 CDC27 SPEN

1.44e-061889786735_DN
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A

ADNP2 IQGAP1 MET BPTF CDC27 AKAP1 SPEN

1.17e-051799774585_DN
DrugCloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A

RBL2 WNK1 EMSY MET CCDC88A CDC27 SPEN

1.66e-051899774271_DN
DrugPempidine tartrate [546-48-5]; Down 200; 13uM; PC3; HT_HG-U133A

RBL2 WNK1 IQGAP1 MET CCDC88A R3HDM1 SPEN

1.72e-051909774307_DN
DrugAC1L2I2N

NR3C1 MET

1.80e-052972CID000021320
DrugAC1O3HPM

F3 SLAMF7

1.80e-052972CID006328862
DrugBenfotiamine [22457-89-2]; Down 200; 8.6uM; PC3; HT_HG-U133A

RC3H2 RBL2 WNK1 IQGAP1 MET CCDC88A SPEN

1.97e-051949774312_DN
DrugBambuterol hydrochloride [81732-46-9]; Down 200; 10uM; HL60; HG-U133A

SP2 WNK1 CCDC88A AP1G1 PDCD11 CDC27 AKAP1

2.03e-051959771582_DN
DrugMometasone Furoate

NR3C1 F3 VCAM1

2.08e-0513973ctd:D000068656
Diseasechronic kidney disease (biomarker_via_orthology)

SLC19A2 DNM1L VCAM1

1.03e-0428963DOID:784 (biomarker_via_orthology)
Diseasesarcoma (is_marker_for)

MET KDR

1.04e-045962DOID:1115 (is_marker_for)
Diseasepseudohypoaldosteronism (implicated_via_orthology)

WNK1 WNK3

1.56e-046962DOID:4479 (implicated_via_orthology)
Diseaseobsolete_red blood cell distribution width

SEMA3C EP400 TTC28 LIN54 ZNF407 ZCCHC2 WNK1 F3 IQGAP1 ALAS2 R3HDM1 ZNF443 WNK3

4.20e-0413479613EFO_0005192
DiseaseMalignant neoplasm of breast

XIRP1 SIX4 WNK1 F3 EMSY NFYC MACF1 KDR HERC2 CDC27 SPEN

7.39e-0410749611C0006142
Diseasemean corpuscular hemoglobin concentration

VIL1 SEMA3C EP400 TTC28 LIN54 F3 ZNF638 MACF1 ALAS2 LRIF1 EPB41

9.31e-0411059611EFO_0004528
DiseaseMicrocephaly

PNKP DNM1L CCDC88A

1.37e-0367963C0025958
Diseasesmoking status measurement

TMEM63C ZNF407 TMEM225B ACYP2 F3 TENM2 PHF21A MET BPTF RAB2B BICRAL

1.38e-0311609611EFO_0006527
DiseaseUremia

KDR VCAM1

1.38e-0317962C0041948
Diseaselupus nephritis (is_marker_for)

NR3C1 VCAM1

1.38e-0317962DOID:0080162 (is_marker_for)
DiseaseManic Disorder

SP4 NR3C1 ZCCHC2

1.63e-0371963C0024713
DiseaseDeep Vein Thrombosis

F3 KDR

2.11e-0321962C0149871
Diseaseperiodontitis (biomarker_via_orthology)

MET VCAM1

2.11e-0321962DOID:824 (biomarker_via_orthology)
DiseaseVenous Thrombosis

F3 KDR

2.11e-0321962C0042487
DiseaseManic

SP4 NR3C1 ZCCHC2

2.13e-0378963C0338831
DiseaseDepression, Bipolar

SP4 NR3C1 ZCCHC2

2.21e-0379963C0005587
Diseaselung non-small cell carcinoma (is_marker_for)

LAMB3 NR3C1 MET KDR

2.29e-03169964DOID:3908 (is_marker_for)
Diseasered blood cell density measurement

VIL1 SP4 SEMA3C EP400 LIN54 WNK1 F3 ARID2 TAF4B

2.30e-03880969EFO_0007978
Diseasedepressive disorder (implicated_via_orthology)

GPM6B NR3C1

2.32e-0322962DOID:1596 (implicated_via_orthology)
DiseaseMyocardial Ischemia

DNM1L F3 KDR VCAM1

2.65e-03176964C0151744
Diseaseage at menopause

TTC28 ZCCHC2 TASOR2 PIK3CG LRIF1

3.11e-03302965EFO_0004704
Diseaseblood rubidium measurement

TAF4B LRIF1

3.24e-0326962EFO_0021529

Protein segments in the cluster

PeptideGeneStartEntry
KNTSKGTVTGQVQGP

ACYP2

41

P14621
VQQKITAQQITTPGA

EP400

2991

Q96L91
IEVTVPTSNGDQTQK

EPB41

621

P11171
GKSSSSQVVGPVQEE

AKAP1

246

Q92667
LGVKVQVTINPGTQT

CD300LD

116

Q6UXZ3
PQIVVVGTQSSGKSS

DNM1L

26

O00429
TKPTEGQDVTLTVQG

CEACAM16

326

Q2WEN9
GNTTETVTLVGPTNK

FAM78B

116

Q5VT40
GTSGNQVTITVVPNT

ARID2

1166

Q68CP9
NVTIPIIGLNNSGKT

ARL13A

21

Q5H913
SNIPTEIKDGQQSGT

ANKRD36

1176

A6QL64
ATEIKEGQQSGTVSP

ANKRD36B

311

Q8N2N9
NIPTEIKDGQQSGTV

ANKRD36B

581

Q8N2N9
QQKVLGIIPSSTGTS

BPTF

2131

Q12830
VNKSVGTSVLPINQT

ADNP2

381

Q6IQ32
SKVDQIQEIVTGNPT

IQGAP1

1036

P46940
GIVGVQQPQSQSLVS

R3HDM1

696

Q15032
TGKIVPSTNGISNAE

RC3H2

486

Q9HBD1
EANGIKIGPQQSIST

RAB2B

181

Q8WUD1
TLQTSKELPQGTSGQ

NOL11

296

Q9H8H0
SQQVTGTTLQVPGQV

RBL2

791

Q08999
TTNGPTEIVQTNGET

AP1G1

591

O43747
TEIKEGQQSGTVSPQ

ANKRD36C

636

Q5JPF3
SNIPTEIKDGQQSGT

ANKRD36C

1006

Q5JPF3
PTGIQVKENQPVGSS

FAT1

721

Q14517
VVQTKPVQTSAVTGQ

HCFC1

686

P51610
INSKAVTGQTTQVSP

LIN54

251

Q6MZP7
GVNTKIDTSGNQAVP

EYS

61

Q5T1H1
NTGKPVQVTFQTQIS

LRIF1

71

Q5T3J3
ITVQPETQSAIKGSN

LRIG3

501

Q6UXM1
NGTTTVNRKPTLVQG

HERC2

3291

O95714
PGGIQEVTVNQSLLT

KRT79

111

Q5XKE5
GVQPQQSSVTTIVKS

TMEM63C

366

Q9P1W3
IKTGSPGSEVVTLQQ

CCDC88A

1671

Q3V6T2
QTSSKVTGPGAEAVQ

PHF21A

181

Q96BD5
SEPVGTQTAKIQQQI

MACF1

1606

O94854
GVSQETSENPGNKTI

NR3C1

506

P04150
GGQTIVQLQKETGAT

NOVA2

51

Q9UNW9
IKSPQTNGTTGVEQI

GPM6B

171

Q13491
FSGPQEQEQISGKVT

ALAS2

116

P22557
PVSGTQVVQGQIQTL

NFYC

256

Q13952
TGPGDVSLSTSQVQK

MACF1

4646

Q9UPN3
VGPSQVIVKNLSSGT

IFT172

331

Q9UG01
PVSKQQSQGSIGETT

FCAMR

351

Q8WWV6
VIVNINGKPITTTTD

HTRA4

431

P83105
TAGPGLTNTVTAVKN

ILVBL

121

A1L0T0
IILKGSGQQAPSNVS

BICRAL

236

Q6AI39
LGTAQPQQEKVVGSS

BICRAL

661

Q6AI39
EGKQVGSGVTTDQVQ

IGHM

151

P01871
VIGQLTIQTGSSTKP

COL12A1

106

Q99715
TQGLTPFTVTTKNQN

FCGBP

4111

Q9Y6R7
SLEKQGIPSQQVGSQ

CPHXL2

171

A0A1W2PPK0
DKPGTTQIVQLTQQV

DENND6A

241

Q8IWF6
LVSGIPATQSQKIQE

LAMB3

196

Q13751
PATQSQKIQEVGEIT

LAMB3

201

Q13751
PNVIVVQKTTGKGTT

EMSY

576

Q7Z589
KQTASQVEQPIITQG

EMSY

1086

Q7Z589
QVEQPIITQGSSVTK

EMSY

1091

Q7Z589
GISLTTQQAQKLGIP

FAM186A

1156

A6NE01
TSVTQPSELLQQKGV

SEC24B

341

O95487
KVQNGGIVTDTPASN

SLC19A2

231

O60779
PLGTGTSILSKQVQN

CDC27

246

P30260
IQVTKVTQVDGNSPV

ARCN1

481

P48444
SSTVLGKVIVQPDQN

MET

916

P08581
VVQQPSGGNEKQVTT

TAF4B

531

Q92750
VLSLTQPTQVGVGKQ

TAF4

721

O00268
NQKGQGEIVSTLLPS

USO1

396

O60763
VPVTITSVAGQQQGQ

SP4

551

Q02446
TVISVNPSTKLQEGG

VCAM1

226

P19320
QVKSGSLPVGTFVQT

TCEANC2

191

Q96MN5
VQKVVVLPTNNSVSG

SEMA3C

456

Q99985
SLGGEPSSVQKETQV

TMEM225B

201

P0DP42
VGTQTSVRQLQLGPK

SYNM

1256

O15061
GGSVVTFTTPVQINQ

SIX4

466

Q9UIU6
TVPNTGQTIGSVKQE

SIX4

556

Q9UIU6
KVLESGVNVTVSQPT

TENM2

2641

Q9NT68
GVNVTVSQPTLLVNG

TENM2

2646

Q9NT68
TVAVKQLGVNPSTTG

PNKP

61

Q96T60
QLGVNPSTTGTQELK

PNKP

66

Q96T60
GNESIVAKTTVTVPN

RACGAP1

211

Q9H0H5
KPQGFISLQGTQVTE

ARHGAP22

76

Q7Z5H3
APKTQADVTTVNGTQ

CKAP2L

436

Q8IYA6
EGNTGTVPQPTNVKV

ZCCHC2

886

Q9C0B9
TTIAKIQQSTVGNTG

PIK3CG

886

P48736
QVGQGVSLTLKTTEP

PDCD11

971

Q14690
AQVKGSLNITTPGLQ

VIL1

6

P09327
TQTQDSIVNEKIPGV

ZNF441

86

Q8N8Z8
TPVTQGGTVKVLTQG

SPEN

2921

Q96T58
PQVSQEAKGTQTGVE

SPEN

3386

Q96T58
PTVSQLTQKAGEGEQ

TUT1

451

Q9H6E5
TTPVQSGANVVKLTG

SP2

191

Q02086
VQGVPVTITNTGGQQ

SP2

446

Q02086
QGPVKSNNIVTVTGI

THSD1

406

Q9NS62
LVVNGKPQGSSSQAV

TTC5

416

Q8N0Z6
IGTGKTATPQQAQEV

TPI1

171

P60174
QIQDSIVTKNTLPGV

ZNF799

86

Q96GE5
VKGQLGSTQSQGLVP

NUP188

691

Q5SRE5
VTIQPEGGTIIVTQN

SLAMF7

61

Q9NQ25
GQPTIQSFEQVGTKV

F3

141

P13726
TSQQSVENKVGGIPG

TTC28

1766

Q96AY4
GTSSNSVKQTGQITV

TRAV40

16

A0A0B4J280
QIQDSIVTKNTLPGV

ZNF443

86

Q9Y2A4
APSGIVNVSVKQQTS

TASOR2

1596

Q5VWN6
EIGVQTGSTAQILQP

KDR

1331

P35968
SLSPGGAVIQQVTKQ

ZNF407

1956

Q9C0G0
ITEAGTQPQKGVSQV

WNK1

1826

Q9H4A3
DTGQPTKVGRFQVTT

WNK1

1936

Q9H4A3
EGSTQKVESPVLQGQ

TRMT10B

6

Q6PF06
GGTQTAIVFIKQPSS

PTK7

26

Q13308
QKSVLELQTGPGSSQ

XIRP1

1746

Q702N8
GQSVLEPIKSVNQSI

ZNF638

301

Q14966
GISGTTQQSVVIPAQ

WNK3

1756

Q9BYP7