Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	HOOK3 CENPF CEP135 OBSCN CKAP5 DNM3 KIF2A NEDD1 SHTN1 FMNL2 FMNL1 OPHN1	5.15e-05	1099	57	12	GO:0008092
GeneOntologyMolecularFunction	tubulin binding	HOOK3 CENPF CEP135 CKAP5 DNM3 KIF2A NEDD1	2.08e-04	428	57	7	GO:0015631
GeneOntologyMolecularFunction	microtubule binding	HOOK3 CENPF CEP135 CKAP5 DNM3 KIF2A	2.40e-04	308	57	6	GO:0008017
GeneOntologyMolecularFunction	cadherin binding	PTPRO CCNB2 OBSCN CKAP5 SHTN1 FMNL2	4.01e-04	339	57	6	GO:0045296
Domain	Cdc37_Hsp90-bd	CDC37 CDC37L1	8.83e-06	2	56	2	IPR013874
Domain	CDC37_M	CDC37 CDC37L1	8.83e-06	2	56	2	PF08565
Domain	ATPase_V1/A1-cplx_esu	ATP6V1E1 ATP6V1E2	8.83e-06	2	56	2	IPR002842
Domain	Cdc37	CDC37 CDC37L1	8.83e-06	2	56	2	IPR004918
Domain	vATP-synt_E	ATP6V1E1 ATP6V1E2	8.83e-06	2	56	2	PF01991
Domain	CDC37_M	CDC37 CDC37L1	8.83e-06	2	56	2	SM01070
Domain	DAD_dom	FMNL2 FMNL1	2.44e-04	8	56	2	IPR014767
Domain	DAD	FMNL2 FMNL1	2.44e-04	8	56	2	PS51231
Domain	Drf_GBD	FMNL2 FMNL1	3.14e-04	9	56	2	PF06371
Domain	FH3_dom	FMNL2 FMNL1	3.14e-04	9	56	2	IPR010472
Domain	GTPase-bd	FMNL2 FMNL1	3.14e-04	9	56	2	IPR010473
Domain	Drf_FH3	FMNL2 FMNL1	3.14e-04	9	56	2	PF06367
Domain	Drf_FH3	FMNL2 FMNL1	3.14e-04	9	56	2	SM01139
Domain	Drf_GBD	FMNL2 FMNL1	3.14e-04	9	56	2	SM01140
Domain	GBD/FH3_dom	FMNL2 FMNL1	4.77e-04	11	56	2	IPR014768
Domain	GBD_FH3	FMNL2 FMNL1	4.77e-04	11	56	2	PS51232
Domain	RabGAP-TBC	TBC1D1 TBC1D28 TBC1D26	5.38e-04	53	56	3	PF00566
Domain	TBC_RABGAP	TBC1D1 TBC1D28 TBC1D26	6.00e-04	55	56	3	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D1 TBC1D28 TBC1D26	6.00e-04	55	56	3	IPR000195
Domain	I-BAR_dom	ARHGAP42 OPHN1	6.74e-04	13	56	2	IPR013606
Domain	FH2	FMNL2 FMNL1	9.04e-04	15	56	2	PS51444
Domain	FH2_Formin	FMNL2 FMNL1	9.04e-04	15	56	2	IPR015425
Domain	FH2	FMNL2 FMNL1	9.04e-04	15	56	2	PF02181
Domain	FH2	FMNL2 FMNL1	9.04e-04	15	56	2	SM00498
Domain	HEAT_type_2	PPP4R1 CKAP5	1.17e-03	17	56	2	IPR021133
Domain	JmjC	KDM5D UTY	2.34e-03	24	56	2	PF02373
Domain	ARM-type_fold	PPP4R1 DNAJC13 CKAP5 FMNL2 FMNL1	3.42e-03	339	56	5	IPR016024
Domain	JMJC	KDM5D UTY	4.13e-03	32	56	2	PS51184
Domain	JmjC_dom	KDM5D UTY	4.13e-03	32	56	2	IPR003347
Domain	JmjC	KDM5D UTY	4.39e-03	33	56	2	SM00558
Domain	PH	ARHGAP42 OBSCN DNM3 OPHN1	4.91e-03	229	56	4	PF00169
Domain	PTPc	PTPRO PTPN22	5.21e-03	36	56	2	SM00194
Domain	BROMODOMAIN_1	TRIM33 BRD8	5.50e-03	37	56	2	PS00633
Domain	Bromodomain	TRIM33 BRD8	5.79e-03	38	56	2	PF00439
Domain	TYR_PHOSPHATASE_PTP	PTPRO PTPN22	6.09e-03	39	56	2	PS50055
Domain	-	ARHGAP42 TBC1D1 OBSCN DNM3 OPHN1	6.24e-03	391	56	5	2.30.29.30
Domain	PTPase_domain	PTPRO PTPN22	6.72e-03	41	56	2	IPR000242
Domain	Y_phosphatase	PTPRO PTPN22	6.72e-03	41	56	2	PF00102
Domain	BROMODOMAIN_2	TRIM33 BRD8	6.72e-03	41	56	2	PS50014
Domain	BROMO	TRIM33 BRD8	7.04e-03	42	56	2	SM00297
Domain	Bromodomain	TRIM33 BRD8	7.04e-03	42	56	2	IPR001487
Domain	-	TRIM33 BRD8	7.04e-03	42	56	2	1.20.920.10
Domain	PH_dom-like	ARHGAP42 TBC1D1 OBSCN DNM3 OPHN1	8.87e-03	426	56	5	IPR011993
Pathway	REACTOME_MITOTIC_PROMETAPHASE	CENPF CCNB2 CEP135 CKAP5 KIF2A NEDD1	3.60e-05	202	44	6	MM15362
Pathway	REACTOME_MITOTIC_PROMETAPHASE	CENPF CCNB2 CEP135 CKAP5 KIF2A NEDD1	3.81e-05	204	44	6	M4217
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	CENPF CKAP5 KIF2A FMNL2 FMNL1	7.15e-05	140	44	5	M27550
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	CENPF CKAP5 KIF2A FMNL2 FMNL1	7.40e-05	141	44	5	MM15266
Pathway	REACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION	CCNB2 CEP135 CKAP5 NEDD1	1.39e-04	85	44	4	MM14906
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	ARHGAP42 CDC37 CENPF OBSCN CKAP5 KIF2A FMNL2 FMNL1 OPHN1	1.46e-04	649	44	9	MM15690
Pathway	REACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION	CCNB2 CEP135 CKAP5 NEDD1	1.52e-04	87	44	4	M27194
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	ARHGAP42 CDC37 CENPF OBSCN CKAP5 KIF2A FMNL2 FMNL1 OPHN1	3.18e-04	720	44	9	M41838
Pathway	REACTOME_MITOTIC_G2_G2_M_PHASES	CENPF CCNB2 CEP135 CKAP5 NEDD1	3.79e-04	200	44	5	M864
Pathway	KEGG_VIBRIO_CHOLERAE_INFECTION	ATP6V1E1 ATP6V1E2 MUC2	6.30e-04	54	44	3	M17906
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	CENPF CCNB2 CKAP5 KIF2A	6.45e-04	127	44	4	M27181
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	CENPF CCNB2 CKAP5 KIF2A	6.84e-04	129	44	4	MM14894
Pathway	REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS	CENPF CCNB2	1.11e-03	16	44	2	M26971
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	CENPF CKAP5 KIF2A FMNL2 FMNL1	1.18e-03	257	44	5	MM14755
Pathway	REACTOME_M_PHASE	CENPF CCNB2 CEP135 CKAP5 KIF2A NEDD1	1.20e-03	387	44	6	MM15364
Pathway	REACTOME_CDC42_GTPASE_CYCLE	ARHGAP42 FMNL2 FMNL1 OPHN1	1.36e-03	155	44	4	M41808
Pathway	REACTOME_AURKA_ACTIVATION_BY_TPX2	CEP135 CKAP5 NEDD1	1.40e-03	71	44	3	MM15495
Pathway	REACTOME_AURKA_ACTIVATION_BY_TPX2	CEP135 CKAP5 NEDD1	1.46e-03	72	44	3	M27749
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	CCNB2 KIAA0586 CEP135 CKAP5 KIF2A NEDD1	1.85e-07	146	59	6	21399614
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ILF2 MDN1 CENPF AGL MCUR1 OBSCN CKAP5 POTEA FMNL2 SNRNP200	4.18e-07	736	59	10	29676528
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DNAJC13 ILF2 HOOK3 MDN1 CENPF CKAP5 DNM3 KIF2A SPATS2 SHTN1 TRIP11	5.76e-07	963	59	11	28671696
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CDC37 TRIM33 DNAJC13 ILF2 MDN1 CKAP5 HAT1 KIF2A SNRNP200	1.23e-06	638	59	9	33239621
Pubmed	Defective assembly of a hybrid vacuolar H(+)-ATPase containing the mouse testis-specific E1 isoform and yeast subunits.	ATP6V1E1 ATP6V1E2	2.83e-06	2	59	2	18662668
Pubmed	A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E.	ATP6V1E1 ATP6V1E2	2.83e-06	2	59	2	12036578
Pubmed	Critical roles for multiple formins during cardiac myofibril development and repair.	FMNL2 FMNL1	2.83e-06	2	59	2	24430873
Pubmed	Increased Expression of Y-Encoded Demethylases During Differentiation of Human Male Neural Stem Cells.	KDM5D UTY	2.83e-06	2	59	2	33040644
Pubmed	Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37.	CDC37 CDC37L1	8.48e-06	3	59	2	15850399
Pubmed	A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidification.	ATP6V1E1 ATP6V1E2	8.48e-06	3	59	2	11872743
Pubmed	Population genetic implications from sequence variation in four Y chromosome genes.	KDM5D UTY	8.48e-06	3	59	2	10861003
Pubmed	Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.	FMNL2 FMNL1	8.48e-06	3	59	2	12684686
Pubmed	Transposition of RhoA to the murine Y chromosome.	KDM5D UTY	1.69e-05	4	59	2	9598304
Pubmed	X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.	KDM5D UTY	1.69e-05	4	59	2	32732223
Pubmed	A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family.	ARHGAP42 OPHN1	1.69e-05	4	59	2	18954304
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	CCNB2 KIAA0586 KIF2A NEDD1	2.70e-05	101	59	4	24613305
Pubmed	The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells.	ATP6V1E1 ATP6V1E2	2.82e-05	5	59	2	10748165
Pubmed	The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules.	KDM5D UTY	2.82e-05	5	59	2	16299505
Pubmed	DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.	TRIM33 MDN1 CKAP5	2.92e-05	35	59	3	24515614
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	DNAJC13 ILF2 MDN1 CENPF CKAP5 KIF2A SPATS2 SNRNP200	4.12e-05	759	59	8	35915203
Pubmed	Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.	CDC37 TRIM33 ILF2 HAT1	4.19e-05	113	59	4	23403292
Pubmed	The mouse Y chromosome interval necessary for spermatogonial proliferation is gene dense with syntenic homology to the human AZFa region.	KDM5D UTY	5.91e-05	7	59	2	9736773
Pubmed	Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice.	KDM5D UTY	5.91e-05	7	59	2	24105479
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	CDC37 CENPF CKAP5 SHTN1 SNRNP200	7.52e-05	256	59	5	33397691
Pubmed	TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.	CKAP5 KIF2A	7.87e-05	8	59	2	26323690
Pubmed	Common genetic variants on 1p13.2 associate with risk of autism.	TRIM33 NEDD1	7.87e-05	8	59	2	24189344
Pubmed	Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity.	CKAP5 KIF2A	7.87e-05	8	59	2	19996280
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	TRIM33 ILF2 MDN1 CENPF KIF2A CAVIN2	1.19e-04	453	59	6	29656893
Pubmed	The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.	CEP135 CKAP5 NEDD1	1.21e-04	56	59	3	11076968
Pubmed	Identification and characterization of Harc, a novel Hsp90-associating relative of Cdc37.	CDC37 CDC37L1	1.26e-04	10	59	2	11413142
Pubmed	An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19.	CKAP5 SNRNP200	1.26e-04	10	59	2	23500468
Pubmed	BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia.	DTNBP1 TRIP11	1.26e-04	10	59	2	28576874
Pubmed	MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.	CKAP5 KIF2A NEDD1	1.27e-04	57	59	3	29089450
Pubmed	The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.	CEP135 CKAP5 NEDD1	1.27e-04	57	59	3	16462731
Pubmed	Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.	CEP135 CKAP5 NEDD1	1.34e-04	58	59	3	12852856
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	ILF2 SPATS2 NEDD1 FMNL1 CAVIN2 OPHN1	1.54e-04	475	59	6	31040226
Pubmed	Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.	CEP135 CKAP5 NEDD1	1.56e-04	61	59	3	7790358
Pubmed	A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.	CDC37 SNRNP200 CDC37L1	1.56e-04	61	59	3	19875381
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	ILF2 CENPF OBSCN CKAP5 SNRNP200	1.68e-04	304	59	5	32235678
Pubmed	Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.	CENPF NEDD1 SHTN1 FMNL2	1.81e-04	165	59	4	16107646
Pubmed	The role of Dby mRNA in early development of male mouse zygotes.	KDM5D UTY	1.85e-04	12	59	2	20543856
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	CDC37 TRIM33 ILF2 CENPF AGL HAT1 SNRNP200	1.85e-04	704	59	7	29955894
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	CDC37 ILF2 CENPF AGL CKAP5 SNRNP200	1.90e-04	494	59	6	26831064
Pubmed	Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.	CEP135 CKAP5 NEDD1	1.97e-04	66	59	3	12221128
Pubmed	Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.	KDM5D UTY	2.18e-04	13	59	2	14660691
Pubmed	NCOA2 promotes lytic reactivation of Kaposi's sarcoma-associated herpesvirus by enhancing the expression of the master switch protein RTA.	ILF2 ATP6V1E2 SNRNP200	2.34e-04	70	59	3	31751430
Pubmed	Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.	ILF2 DNM3 HAT1 SNRNP200	2.53e-04	180	59	4	30110629
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	FMNL2 FMNL1	2.54e-04	14	59	2	26272686
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	CDC37 DNAJC13 VPS8 TRIP11 FMNL1	2.78e-04	339	59	5	37232246
Pubmed	Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.	MLH3 MDN1	2.93e-04	15	59	2	19762545
Pubmed	CKS proteins protect mitochondrial genome integrity by interacting with mitochondrial single-stranded DNA-binding protein.	CDC37 CCNB2	2.93e-04	15	59	2	19786724
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	BRD8 ILF2 MDN1 CENPF CCNB2 CKAP5 ELOVL1 SNRNP200 ITPR3	3.13e-04	1294	59	9	30804502
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ILF2 HOOK3 MDN1 CENPF CKAP5 KIF2A SNRNP200 ITPR3	3.22e-04	1024	59	8	24711643
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	PPP4R1 ATP6V1E1 BRD8 ILF2 MCUR1 CEP135 NEDD1 CAVIN2 FBXW7	3.76e-04	1327	59	9	32694731
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP4R1 DNAJC13 CCNB2 CEP135 PTPN22 DTNBP1 ITPR3 FBXW7	3.78e-04	1049	59	8	27880917
Pubmed	Examining post-translational modification-mediated protein-protein interactions using a chemical proteomics approach.	HAT1 KIF2A	3.79e-04	17	59	2	23281010
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	DNAJC13 CKAP5 SNRNP200 ITPR3	3.92e-04	202	59	4	33005030
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	CKAP5 ELOVL1 SHTN1 TRIP11 FMNL1 ITPR3	4.00e-04	568	59	6	37774976
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	NEDD1 TRIP11 SNRNP200	4.15e-04	85	59	3	16051665
Pubmed	PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth.	ITPR3 FBXW7	4.25e-04	18	59	2	28614300
Pubmed	M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.	BRD8 FBXW7	4.25e-04	18	59	2	15070733
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	KDM5D UTY	4.25e-04	18	59	2	12023983
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	MDN1 CKAP5 SPATS2 SNRNP200 ITPR3	4.41e-04	375	59	5	32788342
Pubmed	A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.	CDC37 TBC1D1 TRIP11	4.44e-04	87	59	3	17979178
Pubmed	Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.	ATP6V1E1 ATP6V1E2	5.27e-04	20	59	2	22982048
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TRIM33 ILF2 CKAP5 HAT1 PTPN22 KIF2A NEDD1 SNRNP200	5.27e-04	1103	59	8	34189442
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	TRIM33 MLH3 MDN1 KIF2A	5.59e-04	222	59	4	37071664
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	ATP6V1E1 ILF2 MDN1 CKAP5 DNM3 HAT1 SNRNP200	5.63e-04	847	59	7	35235311
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	CDC37 ILF2 MDN1 HAT1 KIF2A	5.90e-04	400	59	5	35013556
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	CREBRF MDN1 CKAP5 NEDD1	5.97e-04	226	59	4	25900982
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CDC37 ILF2 MDN1 CENPF KIAA0586 CKAP5 HAT1 KIF2A SNRNP200	6.28e-04	1425	59	9	30948266
Pubmed	Proton translocation driven by ATP hydrolysis in V-ATPases.	ATP6V1E1 ATP6V1E2	6.39e-04	22	59	2	12788495
Pubmed	Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.	TBC1D1 ITPR3	6.39e-04	22	59	2	23850713
Pubmed	Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.	ATP6V1E1 ATP6V1E2	6.39e-04	22	59	2	14580332
Pubmed	Neurotransmitter release: the dark side of the vacuolar-H+ATPase.	ATP6V1E1 ATP6V1E2	6.39e-04	22	59	2	14597263
Pubmed	The vacuolar (H+)-ATPases--nature's most versatile proton pumps.	ATP6V1E1 ATP6V1E2	6.39e-04	22	59	2	11836511
Pubmed	Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation.	ATP6V1E1 ATP6V1E2	6.39e-04	22	59	2	17662945
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ATP6V1E1 DNAJC13 ILF2 CKAP5 KIF2A FMNL2 TRIP11 SNRNP200 OPHN1	6.48e-04	1431	59	9	37142655
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	TRIM33 ILF2 CKAP5 KDM5D SNRNP200	6.67e-04	411	59	5	35182466
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	CDC37 ILF2 MDN1 AGL CKAP5 HAT1 SHTN1 SNRNP200	6.89e-04	1149	59	8	35446349
Pubmed	A protein interaction landscape of breast cancer.	CDC37 MDN1 CCNB2 TRIP11 CAVIN2 ITPR3	7.12e-04	634	59	6	34591612
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CDC37 PPP4R1 ATP6V1E1 ILF2 AGL HAT1 SHTN1 SNRNP200 CDC37L1	7.29e-04	1455	59	9	22863883
Pubmed	Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.	VPS8 UTY	7.62e-04	24	59	2	17452356
Pubmed	Defining the membrane proteome of NK cells.	DNAJC13 ILF2 MDN1 CKAP5 ELOVL1 KIF2A FMNL1 ITPR3	7.67e-04	1168	59	8	19946888
Pubmed	Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics.	CDC37 DNAJC13 CAVIN2	7.69e-04	105	59	3	29491746
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	CDC37 TRIM33 BRD8 ILF2 KIF2A	7.75e-04	425	59	5	24999758
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ATP6V1E1 BRD8 CEP135 CKAP5 HAT1 SHTN1	7.78e-04	645	59	6	25281560
Pubmed	Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.	ATP6V1E1 ATP6V1E2	8.28e-04	25	59	2	2874839
Pubmed	Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit.	CCNB2 CEP135	8.28e-04	25	59	2	28923932
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ILF2 MDN1 CENPF CKAP5 SNRNP200 ITPR3	8.29e-04	653	59	6	22586326
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	ATP6V1E1 KIF2A FMNL2 SNRNP200 CAVIN2 ITPR3	8.76e-04	660	59	6	32780723
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	CDC37 ILF2 MDN1 CENPF MCUR1 KIF2A SPATS2 TRIP11 ITPR3	8.88e-04	1496	59	9	32877691
Pubmed	Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.	CDC37 ILF2	9.66e-04	27	59	2	36266428
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	FMNL2 FMNL1	1.12e-03	29	59	2	21834987
Pubmed	Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin.	ILF2 SNRNP200	1.19e-03	30	59	2	24140279
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CDC37 ILF2 CENPF CKAP5 KIF2A SPATS2 SNRNP200 ITPR3	1.23e-03	1257	59	8	36526897
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	CDC37 PTPRO AGL CKAP5 NEDD1 SNRNP200 ITPR3	1.27e-03	974	59	7	28675297
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	DNAJC13 CKAP5 DNM3	1.36e-03	128	59	3	30995482
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	TRIM33 ILF2 MDN1 CENPF HAT1 KIF2A SNRNP200	1.39e-03	989	59	7	36424410
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	MDN1 KIF2A FBXW7	1.39e-03	129	59	3	23022380
Cytoband	Yq11	KDM5D UTY	1.06e-04	12	59	2	Yq11
Cytoband	10q25.3	CCDC186 SHTN1	6.45e-04	29	59	2	10q25.3
GeneFamily	V-type ATPases	ATP6V1E1 ATP6V1E2	7.50e-04	23	32	2	415
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5D UTY	8.17e-04	24	32	2	485
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP42 OPHN1	3.53e-03	50	32	2	721
GeneFamily	Endogenous ligands\|Minor histocompatibility antigens	KDM5D UTY	3.67e-03	51	32	2	870
GeneFamily	WD repeat domain containing	WDR87 NEDD1 FBXW7	1.09e-02	262	32	3	362
GeneFamily	PHD finger proteins	TRIM33 KDM5D	1.10e-02	90	32	2	88
Coexpression	ZHONG_PFC_C1_OPC	BRD8 CENPF CCNB2 KIAA0586 CEP135 CKAP5 CCDC150	9.45e-07	238	58	7	M39096
Coexpression	HEVNER_Y_CHROMOSOME_EXPRESSION	KDM5D UTY	2.88e-05	4	58	2	MM451
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL	PPP4R1 BRD8 CENPF CCNB2 KIAA0586 MCUR1 CEP135 CKAP5 HAT1 NEDD1	3.63e-05	939	58	10	M45768
Coexpression	ZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_CORRELATED_WITH_CD8_T_CELL_RESPONSE_3DY_POSITIVE	HOOK3 CCDC186 PTPN22 KIF2A	3.65e-05	84	58	4	M40895
Coexpression	FISCHER_DREAM_TARGETS	BRD8 CENPF CCNB2 CEP135 CKAP5 CCDC150 HAT1 KIF2A SPATS2 NEDD1	4.74e-05	969	58	10	M149
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	TRIM33 DNAJC13 MDN1 CENPF CEP135 CKAP5 KIF2A	7.38e-05	466	58	7	M13522
Coexpression	HALLMARK_MITOTIC_SPINDLE	HOOK3 CENPF CCNB2 CKAP5 OPHN1	7.93e-05	199	58	5	M5893
Coexpression	GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN	PPP4R1 MLH3 MDN1 CDC37L1 FBXW7	8.12e-05	200	58	5	M9486
Coexpression	BENPORATH_CYCLING_GENES	BRD8 ILF2 CENPF CCNB2 KIAA0586 CKAP5 SHTN1 ITPR3	8.62e-05	648	58	8	M8156
Coexpression	WHITEFORD_PEDIATRIC_CANCER_MARKERS	ILF2 CENPF CCNB2 SNRNP200	1.33e-04	117	58	4	M7854
Coexpression	HE_LIM_SUN_FETAL_LUNG_C2_MEGAKARYOCYTE	MLH3 CKAP5 DNM3 SPATS2 UTY CDC37L1 CAVIN2 OPHN1	1.38e-04	694	58	8	M45731
Coexpression	FAN_EMBRYONIC_CTX_NSC_2	ILF2 CENPF CCNB2 CEP135 CKAP5	1.66e-04	233	58	5	M39036
Coexpression	RUNNE_GENDER_EFFECT_UP	KDM5D UTY	1.72e-04	9	58	2	M17072
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CENPF CCNB2 KIAA0586 CEP135 CKAP5 CCDC150	2.02e-07	191	59	6	0ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell	PND01-03-samps-Mesenchymal-Pericyte-pericyte_E\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ARHGAP42 AXDND1 AGL OBSCN KDM5D	9.92e-07	135	59	5	35928195cf34f055b353562c96f451aef2344d64
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ARHGAP42 CENPF CCNB2 CEP135 CKAP5	3.55e-06	175	59	5	0b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 HAT1 SHTN1 FBXW7	3.96e-06	179	59	5	d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CENPF CCNB2 KIAA0586 CKAP5 CCDC150	5.58e-06	192	59	5	026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BRD8 CENPF CCNB2 CKAP5 CAVIN2	6.32e-06	197	59	5	1c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BRD8 ILF2 CENPF CCNB2 CKAP5	6.48e-06	198	59	5	c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	TRIM33 CENPF CCDC186 KIF2A TRIP11	6.48e-06	198	59	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 KIAA0586 CEP135 CKAP5	6.48e-06	198	59	5	5f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 KIAA0586 CEP135 CKAP5	6.48e-06	198	59	5	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	Sepsis-ICU-SEP-Lymphocyte-B-Plasmablast\|ICU-SEP / Disease, condition lineage and cell class	ARHGAP42 CENPF CCNB2 MCUR1 SPATS2	6.64e-06	199	59	5	09f02aaedf19f895a7b6f8eb939fd346b1df75f1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 KIAA0586 CEP135 CKAP5	6.64e-06	199	59	5	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BRD8 ILF2 CENPF CCNB2 CCDC150	6.64e-06	199	59	5	c7c501ad144ac5488d0b0496554d46616f2e01a6
ToppCell	Endothelial-H_(cycle)\|World / shred on cell class and cell subclass (v4)	ILF2 CENPF CCNB2 CKAP5	2.93e-05	133	59	4	8e3005114761feee028c496cc739e607b35d7831
ToppCell	Endothelial-Endothelial-H_(cycle)\|Endothelial / shred on cell class and cell subclass (v4)	CENPF CCNB2 CKAP5 SLC36A3	3.38e-05	138	59	4	a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF PTPRO CCNB2 CKAP5	3.78e-05	142	59	4	be63c48794a227ea55978524c0f5935342fc455e
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF PTPRO CCNB2 NEDD1	4.22e-05	146	59	4	45d7cb73776e60d22f335a651845e21e16948fcc
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CASP10 SPATS2 KDM5D FBXW7	7.27e-05	168	59	4	f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF CCNB2 WDR87 CKAP5	7.44e-05	169	59	4	563c267edaade0e5df192ad953801ef9768d4270
ToppCell	normal-na-Lymphocytic_B-B_plasma-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CCNB2 CASP10 SPATS2 KDM5D	7.61e-05	170	59	4	c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAJC13 CENPF CCNB2 SHTN1	7.79e-05	171	59	4	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ILF2 CENPF CCNB2 CKAP5	7.97e-05	172	59	4	7f3d0ef18f5df1ed80498d435b0378ca398c0b88
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF CCNB2 TBC1D1 CKAP5	8.52e-05	175	59	4	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ILF2 CENPF CCNB2 CKAP5	9.29e-05	179	59	4	6718cadcc2d3b64717ed84244ef1242d392662dc
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ILF2 CENPF CCNB2 CKAP5	9.50e-05	180	59	4	ed4966765a6b25456f68185cf0648c4a3a21d7fe
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Cplx3-Hs6st2_(Entorhinal_cortex)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TRPA1 STRC MUC2	1.01e-04	68	59	3	01ba0ccc5732189a5c0c32cb7819289102711b93
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Cplx3-Hs6st2_(Entorhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TRPA1 STRC MUC2	1.01e-04	68	59	3	75e81b353ef313d5e98d5c98d584335f1d1fa658
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPF CCNB2 CASP10 CAVIN2	1.01e-04	183	59	4	52af3c943116073c8ddd207b664342960b88929b
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPF CCNB2 CKAP5 SLC36A3	1.01e-04	183	59	4	29b62dd542bc3f8df843998f577724f3818d4271
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF CCNB2 CKAP5 CCDC150	1.06e-04	185	59	4	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ILF2 CENPF CCNB2 CKAP5	1.06e-04	185	59	4	6aeae77a087d695b1e58c5f63265e7113aa2e343
ToppCell	mild_COVID-19-Plasmablast\|World / disease group, cell group and cell class (v2)	ARHGAP42 CCNB2 WDR87 SPATS2	1.12e-04	188	59	4	9a5ba6abdc307402301dae25db2a5f3e0d576417
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MLH3 MCUR1 KIF2A CAVIN2	1.15e-04	189	59	4	d357fa946b9d6af46c15402f68758fb9c747bcaf
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MLH3 MCUR1 KIF2A CAVIN2	1.15e-04	189	59	4	8b4a9434d7b7ca8cf74712227407ed7c96ce02f8
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BRD8 CENPF CCNB2 CKAP5	1.15e-04	189	59	4	d049f33115610bda4489968759f754730698b9cd
ToppCell	Healthy-Platelet\|World / disease group, cell group and cell class	MLH3 DNM3 KIF2A CAVIN2	1.15e-04	189	59	4	c3d8e3682cb489bca887039cbea6c4cfc264de2f
ToppCell	NS-critical-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CENPF CCNB2 SPATS2 ITPR3	1.17e-04	190	59	4	7be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell	mild_COVID-19_(asymptomatic)-Platelet\|World / disease group, cell group and cell class (v2)	MLH3 DNM3 KIF2A CAVIN2	1.17e-04	190	59	4	7aaf82f0c235363afb95cf1fa51c2a5b070b1af8
ToppCell	severe-Platelet\|severe / disease stage, cell group and cell class	MLH3 DNM3 KIF2A CAVIN2	1.17e-04	190	59	4	497ec3fe4dd6f1b4fa6e76d9ac07df497efce7a2
ToppCell	Healthy_donor-Platelet\|World / disease group, cell group and cell class (v2)	MLH3 DNM3 KIF2A CAVIN2	1.19e-04	191	59	4	defae87313d6345e3f451250fd66fe8831bb441c
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MCUR1 DNM3 KIF2A CAVIN2	1.22e-04	192	59	4	f48202c271c9233c78de255a2fa131b219f688d7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CENPF CCNB2 CKAP5 CCDC150	1.22e-04	192	59	4	27723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCell	PBMC-Severe-Hematopoietic-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MCUR1 DNM3 KIF2A CAVIN2	1.22e-04	192	59	4	35ae787e90e7e5e333978125e19de1590316c769
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CENPF CCNB2 CKAP5 CCDC150	1.22e-04	192	59	4	0a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MCUR1 DNM3 KIF2A CAVIN2	1.22e-04	192	59	4	3276bd4f1023a020ebb26ec33424b6e9897d31c9
ToppCell	PBMC-Severe-Hematopoietic-Platelet\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MCUR1 DNM3 KIF2A CAVIN2	1.22e-04	192	59	4	9ae14279e9b91e04ea2c5bbbeadb111a1b966bd1
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ARHGAP42 CENPF CCNB2 SPATS2	1.24e-04	193	59	4	7b4b0271e4fbece703876acb053ae236afb7cdba
ToppCell	mild_COVID-19_(asymptomatic)-Platelet\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	MLH3 DNM3 KIF2A CAVIN2	1.24e-04	193	59	4	9b97a7e9b5c1cc5db353070af0b9c5059714724b
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRPA1 CENPF CCNB2 CKAP5	1.27e-04	194	59	4	7a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-thrombocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MCUR1 DNM3 KIF2A CAVIN2	1.27e-04	194	59	4	7c38ead538695db1fb1c329ff67d2874aa83c8d2
ToppCell	10x5'-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|blood / Manually curated celltypes from each tissue	MCUR1 DNM3 KIF2A CAVIN2	1.27e-04	194	59	4	63dea7d630962761a70aa88e720ee35c22cbc81a
ToppCell	10x5'-blood-Hematopoietic_Erythro-Mega\|blood / Manually curated celltypes from each tissue	MCUR1 DNM3 KIF2A CAVIN2	1.27e-04	194	59	4	d0e7d35b5086834929c4bd39d4c6719b2d5fc71e
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-thrombocytic-platelet\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MCUR1 DNM3 KIF2A CAVIN2	1.27e-04	194	59	4	4531639974e363a6ff7ea688325a11407c3efd87
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	CENPF CCNB2 CKAP5 CCDC150	1.29e-04	195	59	4	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BRD8 CENPF CCNB2 CKAP5	1.29e-04	195	59	4	742c82c86487314cdb3178012004adb1164bcbdb
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF CCNB2 CKAP5 CAVIN2	1.32e-04	196	59	4	0644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF CCNB2 CKAP5 CAVIN2	1.32e-04	196	59	4	20383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BRD8 CENPF CCNB2 CKAP5	1.34e-04	197	59	4	29b0a5927f80455eef7b793feabef69fba1a3df1
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_DC1\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CENPF CCNB2 MCUR1 SHTN1	1.34e-04	197	59	4	9a3d0b7f4788487d024d56bc776a2fd1149f50d5
ToppCell	ILEUM-inflamed-(5)_Plasmablasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CENPF CCNB2 MCUR1 SPATS2	1.34e-04	197	59	4	8710a586fc91cf664032a12e4d2a0399b370cbcb
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF CCNB2 CKAP5 CAVIN2	1.34e-04	197	59	4	a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCell	Sepsis-Bac-SEP-Lymphocyte-B-Plasmablast\|Bac-SEP / Disease, condition lineage and cell class	CENPF CCNB2 MCUR1 SPATS2	1.37e-04	198	59	4	614055c11d1dd2f3f2b8783ec35a8f4570cad161
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	ILF2 CENPF CCNB2 SPATS2	1.40e-04	199	59	4	6748d4f76703360071d5f2026d9d06bf30ccfb6d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	FMNL2 UTY OPHN1 FBXW7	1.40e-04	199	59	4	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	TCGA-Lung-Primary_Tumor\|TCGA-Lung / Sample_Type by Project: Shred V9	ILF2 CENPF CCNB2 SPATS2	1.40e-04	199	59	4	d1d035e987280607266171094db5d6362efe1ad5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 CEP135 CKAP5	1.40e-04	199	59	4	d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CENPF CCNB2 CKAP5 CCDC150	1.40e-04	199	59	4	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CENPF CCNB2 CKAP5 CCDC150	1.40e-04	199	59	4	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 SPATS2 NEDD1	1.42e-04	200	59	4	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CCNB2 DNM3 KIF2A CAVIN2	1.42e-04	200	59	4	e4be88bcef2738915f711b32c95e9c613e7edf96
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CENPF CCNB2 CKAP5 CCDC150	1.42e-04	200	59	4	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 CCDC150 NEDD1	1.42e-04	200	59	4	a854e19703dc920e48304541e2b06ed013292f3e
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 CEP135 CKAP5	1.42e-04	200	59	4	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	CENPF CCNB2 CKAP5 CCDC150	1.42e-04	200	59	4	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CENPF CCNB2 CKAP5 HAT1	1.42e-04	200	59	4	548a0f486ab8745da107f2815914dbf873a6e3c8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 CEP135 CKAP5	1.42e-04	200	59	4	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	mLN-Dendritic_cell-Lymphoid_DC\|Dendritic_cell / Region, Cell class and subclass	BRD8 CEP135 KIF2A FMNL2	1.42e-04	200	59	4	3813fa1ee1462ba83fd8b6253070f46f0b063084
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 SPATS2 NEDD1	1.42e-04	200	59	4	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	CENPF CCNB2 CCDC150 NEDD1	1.42e-04	200	59	4	203b9a5de4430713da01b3331e69381db449a3a0
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP6V1E1 CENPF DTNBP1	2.89e-04	97	59	3	332b4daf5106872dd891d9f9b5a891192d5d9aa8
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	CCDC186 TRIP11 CAVIN2	8.09e-04	138	59	3	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Papillary_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	TRPA1 MUC2 CDC37L1	8.61e-04	141	59	3	330f944b38c3170dfc79ab033fae7b9ab71e840d
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SHTN1 FMNL2 OPHN1	9.34e-04	145	59	3	f6ba6cf0c8d0ee87a7904485b27eb9261fcb6edd
ToppCell	Control-Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CASP10 SPATS2 MUC2	9.34e-04	145	59	3	fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MDN1 CEP135 PTPN22	1.01e-03	149	59	3	65778f19599b4955c0a16f0121237656449431fb
ToppCell	PND01-03-samps-Mesenchymal-Pericyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ARHGAP42 OBSCN KDM5D	1.07e-03	152	59	3	fc9472bc19f997103da535b035105f01429cb08e
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CENPF CCNB2 WDR87	1.09e-03	153	59	3	d7635f3d4831c02a94f53afc674847d5b51453be
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CENPF CCNB2 WDR87	1.09e-03	153	59	3	e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CENPF CCNB2 WDR87	1.09e-03	153	59	3	54a941950bbb848077c7bd5726da9e4b3244bd38
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CENPF CCNB2 WDR87	1.09e-03	153	59	3	69a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCell	Control-PLT_4\|World / Disease Group and Platelet Clusters	CREBRF DNM3 SPATS2	1.11e-03	154	59	3	a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ELOVL1 MUC2 CAVIN2	1.11e-03	154	59	3	e65e4636646164610f33f7bbac0d879a3ea55986
ToppCell	normal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	KDM5D UTY CAVIN2	1.13e-03	155	59	3	08295584395e8d9cfc1b1648f98754b3ac53e587
ToppCell	PND07-28-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PTPRO PTPN22 FMNL1	1.15e-03	156	59	3	166f7b1220eaf8e1149dde260dd85a094855c54f
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP42 TRPA1 ITPR3	1.15e-03	156	59	3	60f1ce38e34b582f589db1e0d6139282c1902b2b
ToppCell	PND07-28-samps-Myeloid-Granulocyte\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PTPRO PTPN22 FMNL1	1.15e-03	156	59	3	5e1c5a7c9293b886920739cf766521df7f69726c
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXDND1 WDR87 SHTN1	1.20e-03	158	59	3	6811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCell	COVID-19-kidney-Plasma\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CASP10 SPATS2 FBXW7	1.24e-03	160	59	3	f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNM3 PTPN22 KDM5D	1.26e-03	161	59	3	d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CENPF CCNB2 CKAP5	1.31e-03	163	59	3	5285318c52aa31c9b22dc2ffff078e32e408604d
Disease	X-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance (implicated_via_orthology)	ARHGAP42 OPHN1	2.27e-05	4	58	2	DOID:0080311 (implicated_via_orthology)
Disease	Diabetes mellitus type 1	PTPN22 ITPR3	2.27e-05	4	58	2	cv:C0011854
Disease	TYPE 1 DIABETES MELLITUS	PTPN22 ITPR3	2.27e-05	4	58	2	222100
Disease	autism	TRIM33 KDM5D UTY	1.17e-04	48	58	3	EFO_0003758
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5D OPHN1	4.48e-04	16	58	2	DOID:0050888 (implicated_via_orthology)
Disease	platelet-to-lymphocyte ratio	CDC37 TBC1D1 DNM3 CDC37L1 ITPR3	7.36e-04	363	58	5	EFO_0008446
Disease	immature platelet count	PPP4R1 DNM3 CAVIN2	1.20e-03	106	58	3	EFO_0803544
Disease	immature platelet fraction	PPP4R1 DNM3 CAVIN2	1.48e-03	114	58	3	EFO_0009187
Disease	immature platelet measurement	PPP4R1 DNM3 CAVIN2	1.68e-03	119	58	3	EFO_0803541
Disease	Colorectal Carcinoma	ATP6V1E1 MLH3 OBSCN HAT1 SNRNP200 FBXW7	2.51e-03	702	58	6	C0009402
Disease	Moyamoya disease	DNM3 FMNL2	2.82e-03	40	58	2	MONDO_0016820
Disease	Diabetes Mellitus, Sudden-Onset	PTPN22 ITPR3	3.41e-03	44	58	2	C4554117
Disease	Diabetes Mellitus, Ketosis-Prone	PTPN22 ITPR3	3.41e-03	44	58	2	C3837958
Disease	Diabetes, Autoimmune	PTPN22 ITPR3	3.41e-03	44	58	2	C0205734

Protein segments in the cluster

Peptide	Gene	Start	Entry
HSVEVQVNMMSENIL	ACOT7L	56	Q6ZUV0
NAVQQLHKEMAQRME	CCDC186	281	Q7Z3E2
HMAVEMRQEVLEQIQ	BRD8	1191	Q9H0E9
TQIMVKTNMYHNEKV	CREBRF	211	Q8IUR6
AAMMNIKFQNIVVEI	OPHN1	541	O60890
FVEMQAQKVMHVSSA	PTPN22	481	Q9Y2R2
QEHIAKQFGMMQSQI	ITPR3	571	Q14573
FQKAQAISVLHEMMQ	IFNA14	71	P01570
IYQMLEKHMQEQTEE	MDN1	3841	Q9NU22
DMVTKMQQEITFQQV	MCUR1	206	Q96AQ8
IVNLQVEMIKQFHMQ	NEDD1	611	Q8NHV4
NLAVAVHKEMFIMVQ	KDM5D	651	Q9BY66
MHLMINNVKDFINSE	DNM3	686	Q9UQ16
FTKGMIHSMQVLQQV	MLH3	1181	Q9UHC1
KTVHMMPMQVQVQVN	MUC2	4551	Q02817
EHAQKVLEMEHTQQM	DTNBP1	176	Q96EV8
KMSVDEFQKVMIEQN	LRRC74A	441	Q0VAA2
VQHVVMTAIQELMSK	HOOK3	146	Q86VS8
MSMVQTEEQYIFIHQ	PTPRO	1176	Q16827
KMMFAKEQSVHNEVQ	OBSCN	1071	Q5VST9
HEAVSQMVEMEEQVV	KIF2A	611	O00139
QEVHQLQEKLAMMES	CEP135	211	Q66GS9
KETNFQVMQMKLHIV	CKAP5	651	Q14008
MNQIEISMQHEQLEE	HAT1	386	O14929
IADHQAILQVEQKMM	CCDC150	371	Q8NCX0
NLMKAEQMHQSFVAE	CENPF	866	P49454
TENEVLEVMQHMAKN	CCNB2	336	O95067
LEVMQHMAKNVVKVN	CCNB2	341	O95067
MEQVAHQTIVMQFIL	CDC37	206	Q16543
TIMHLMINNNKEFIF	DNM1P34	61	Q6PK57
QKYLEAMAVIEHMQE	AXDND1	916	Q5T1B0
KHMMQVIEPQFQRDF	FBXW7	266	Q969H0
FRVHTVMTLEQQDMV	ILF2	296	Q12905
MEAVVNLYQEVMKHA	ELOVL1	1	Q9BW60
MQFINIVVHSVEDMN	FMNL2	321	Q96PY5
TVREMMLEHFKNQQD	DNAJC13	1941	O75165
CMQFINIVVHSVENM	FMNL1	326	O95466
VHIHNNVTKVEMEMV	CASP10	321	Q92851
VNMLDAVQENQHKME	CAVIN2	66	O95810
ALMEQIAHQAVVMQF	CDC37L1	211	Q7L3B6
IAHQAVVMQFIMEMA	CDC37L1	216	Q7L3B6
QLTVEVEQMENMVHV	POTEA	481	Q6S8J7
SQFVLMQQMRHKEVA	UTY	451	O14607
MMKVVQVYADTQEIN	TRIM33	1041	Q9UPN9
HQEAVEQTIMALQMD	PPP4R1	906	Q8TF05
ETVAAMMNIKFQNIV	ARHGAP42	546	A6NI28
QKISHMVIEEVNFMQ	SHTN1	56	A0MZ66
MVIEEVNFMQNHLEI	SHTN1	61	A0MZ66
DQGKIQVMEQHFQDM	VPS8	566	Q8N3P4
HMMFIQRFGVKQQEL	TBC1D26	156	Q86UD7
QQINSMVDFLEVVHM	STRC	1201	Q7RTU9
FMADNLQQMVEKAHV	SLC36A3	156	Q495N2
MTHVAVQMSEQQLVE	SPATS2	316	Q86XZ4
HIAVQGMNNEVMKVL	TRPA1	136	O75762
VQMEKTINQVFEMDI	TBC1D1	1036	Q86TI0
FQIMNEIVYEKIMEH	SNRNP200	701	O75643
LQMVLEHFQQEEKAM	TRIP11	1676	Q15643
NMSKHMIVIHDSVIQ	TTC30A	596	Q86WT1
HMMFIQRFGVKQQEL	TBC1D28	156	Q2M2D7
QIKHMMAFIEQEANE	ATP6V1E1	11	P36543
AQQISIAHKEMEMQY	WDR87	2651	Q6ZQQ6
QMNVFMEQHIRHLEK	KIAA0586	231	Q9BVV6
QIKHMMAFIEQEANE	ATP6V1E2	11	Q96A05
FEVIQEAMQKHMQGI	AGL	1201	P35573