Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

MET ERBB2 ERBB3 LTBP1

3.03e-0585424GO:0019199
GeneOntologyMolecularFunctionmicrofibril binding

LTBP1 LTBP2

6.44e-056422GO:0050436
GeneOntologyMolecularFunctionErbB-3 class receptor binding

ERBB2 ERBB3

6.44e-056422GO:0043125
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM2 GRM4

1.54e-049422GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM2 GRM4

1.54e-049422GO:0001640
GeneOntologyMolecularFunctionE-box binding

MYF6 OLIG3 MYOG

2.86e-0461423GO:0070888
GeneOntologyMolecularFunctiongrowth factor binding

ERBB2 ERBB3 LTBP1 LTBP2

3.18e-04156424GO:0019838
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

MET ERBB2 ERBB3

3.45e-0465423GO:0004714
GeneOntologyMolecularFunctionglutamate receptor activity

GRM2 GRM4

1.47e-0327422GO:0008066
GeneOntologyBiologicalProcesspositive regulation of muscle tissue development

MYF6 ERBB3 MYOG

2.57e-0529413GO:1901863
GeneOntologyCellularComponentERBB3:ERBB2 complex

ERBB2 ERBB3

4.13e-062432GO:0038143
MousePhenoabnormal cell differentiation

ILDR2 MET ERBB2 OLIG3 ERBB3 CSF3R MEGF8 ITGB5 MYOG JAG1

6.86e-067953210MP:0005076
MousePhenoabnormal Schwann cell precursor morphology

ERBB2 ERBB3

1.52e-053322MP:0004074
MousePhenodecreased Schwann cell precursor number

ERBB2 ERBB3

1.52e-053322MP:0004075
MousePhenoabnormal axon fasciculation

ERBB2 ERBB3 MEGF8

1.87e-0523323MP:0009450
MousePhenoabnormal oxygen level

ERBB2 OLIG3 ERBB3 MUC5B LTBP1 MYOG

2.16e-05256326MP:0001574
MousePhenoabnormal ophthalmic nerve morphology

ERBB3 MEGF8

3.04e-054322MP:0009798
MousePhenoabnormal neuron differentiation

MET ERBB2 OLIG3 ERBB3 MEGF8 JAG1

3.23e-05275326MP:0009937
MousePhenorespiratory failure

MET ERBB2 OLIG3 ERBB3 MYOG

3.36e-05165325MP:0001953
MousePhenodecreased respiration

MET ERBB2 OLIG3 ERBB3 MYOG

3.87e-05170325MP:0014274
MousePhenocyanosis

ERBB2 OLIG3 ERBB3 LTBP1 MYOG

1.49e-04226325MP:0001575
MousePhenoperinatal lethality, complete penetrance

MET MYF6 ERBB2 OLIG3 ERBB3 LTBP1 ZNRF3 MYOG

1.54e-04712328MP:0011089
MousePhenoabnormal myogenesis

MET MYF6 MYOG

2.23e-0452323MP:0000729
MousePhenoabnormal trigeminal nerve morphology

ERBB2 ERBB3 MEGF8

2.23e-0452323MP:0001065
MousePhenoabnormal respiration

MET MYF6 ERBB2 OLIG3 ERBB3 MUC5B MYOG

3.35e-04598327MP:0001943
MousePhenoabnormal petrosal ganglion morphology

ERBB2 ERBB3

4.54e-0414322MP:0001084
MousePhenomuscle hypoplasia

MET MYOG

5.23e-0415322MP:0000734
DomainGrowth_fac_rcpt_

ATRN ERBB2 ERBB3 BRINP3 LTBP1 LTBP2 MEGF8 SCARF2 JAG1

3.44e-11156409IPR009030
DomainEGF

ATRN BRINP3 LTBP1 LTBP2 MEGF8 SCARF2 ITGB5 JAG1

3.03e-08235408SM00181
DomainEGF_1

ATRN LTBP1 LTBP2 MEGF8 SSPOP SCARF2 ITGB5 JAG1

5.70e-08255408PS00022
DomainEGF_2

ATRN LTBP1 LTBP2 MEGF8 SSPOP SCARF2 ITGB5 JAG1

7.67e-08265408PS01186
DomainEGF_extracell

ATRN LTBP2 SCARF2 ITGB5 JAG1

1.74e-0760405IPR013111
DomainEGF_2

ATRN LTBP2 SCARF2 ITGB5 JAG1

1.74e-0760405PF07974
DomainEGF_3

ATRN LTBP1 LTBP2 MEGF8 SSPOP SCARF2 JAG1

5.98e-07235407PS50026
DomainEGF-like_CS

ATRN LTBP1 LTBP2 MEGF8 SCARF2 ITGB5 JAG1

1.21e-06261407IPR013032
DomainPSI

ATRN MET MEGF8 ITGB5

2.30e-0644404IPR016201
DomainPSI

ATRN MET MEGF8 ITGB5

2.76e-0646404SM00423
DomainZnf-4CXXC_R1

CDCA7 CDCA7L

4.47e-062402IPR018866
Domainzf-4CXXC_R1

CDCA7 CDCA7L

4.47e-062402PF10497
DomainEGF

ATRN LTBP1 LTBP2 ITGB5 JAG1

7.03e-06126405PF00008
DomainVWC_out

MUC5B SSPOP JAG1

8.61e-0619403SM00215
DomainEGF-like_dom

ATRN LTBP1 LTBP2 MEGF8 SCARF2 JAG1

1.39e-05249406IPR000742
DomainBasic

MYF6 MYOG

2.68e-054402IPR002546
DomainTyr_kinase_EGF/ERB/XmrK_rcpt

ERBB2 ERBB3

2.68e-054402IPR016245
DomainBASIC

MYF6 MYOG

2.68e-054402SM00520
DomainBasic

MYF6 MYOG

2.68e-054402PF01586
DomainEGF_CA

LTBP1 LTBP2 MEGF8 JAG1

3.37e-0586404PF07645
DomainPlexin_repeat

ATRN MET MEGF8

4.32e-0532403IPR002165
DomainPSI

ATRN MET MEGF8

4.32e-0532403PF01437
DomainEGF_Ca-bd_CS

LTBP1 LTBP2 MEGF8 JAG1

5.41e-0597404IPR018097
DomainLaminin_EGF

ATRN MEGF8 SCARF2

5.68e-0535403PF00053
DomainEGF_Lam

ATRN MEGF8 SCARF2

5.68e-0535403SM00180
DomainEGF_CA

LTBP1 LTBP2 MEGF8 JAG1

5.86e-0599404PS01187
DomainASX_HYDROXYL

LTBP1 LTBP2 MEGF8 JAG1

6.10e-05100404PS00010
DomainGF_recep_IV

ERBB2 ERBB3

6.67e-056402PF14843
DomainGF_recep_IV

ERBB2 ERBB3

6.67e-056402IPR032778
DomainVWC

MUC5B SSPOP JAG1

7.29e-0538403SM00214
DomainLaminin_EGF

ATRN MEGF8 SCARF2

7.29e-0538403IPR002049
DomainEGF-type_Asp/Asn_hydroxyl_site

LTBP1 LTBP2 MEGF8 JAG1

7.65e-05106404IPR000152
DomainFurin-like

ERBB2 ERBB3

9.33e-057402PF00757
DomainRcpt_L-dom

ERBB2 ERBB3

9.33e-057402IPR000494
DomainFurin-like_Cys-rich_dom

ERBB2 ERBB3

9.33e-057402IPR006211
DomainRecep_L_domain

ERBB2 ERBB3

9.33e-057402PF01030
Domain-

ERBB2 ERBB3

9.33e-0574023.80.20.20
DomainTB

LTBP1 LTBP2

9.33e-057402PF00683
DomainVWF_dom

MUC5B SSPOP JAG1

9.86e-0542403IPR001007
Domain-

LTBP1 LTBP2

1.24e-0484023.90.290.10
DomainGPCR_3_mtglu_rcpt

GRM2 GRM4

1.24e-048402IPR000162
DomainEGF_CA

LTBP1 LTBP2 MEGF8 JAG1

1.32e-04122404SM00179
DomainEGF-like_Ca-bd_dom

LTBP1 LTBP2 MEGF8 JAG1

1.41e-04124404IPR001881
DomainTB

LTBP1 LTBP2

1.59e-049402PS51364
DomainTB_dom

LTBP1 LTBP2

1.59e-049402IPR017878
DomainPSI_integrin

MEGF8 ITGB5

1.59e-049402PF17205
DomainIntegin_beta_N

MEGF8 ITGB5

1.59e-049402IPR033760
DomainTIL

MUC5B SSPOP

2.91e-0412402PF01826
DomainC8

MUC5B SSPOP

2.91e-0412402PF08742
DomainUnchr_dom_Cys-rich

MUC5B SSPOP

3.44e-0413402IPR014853
DomainNCD3G

GRM2 GRM4

3.44e-0413402PF07562
DomainC8

MUC5B SSPOP

3.44e-0413402SM00832
DomainGPCR_3_9-Cys_dom

GRM2 GRM4

3.44e-0413402IPR011500
DomainGPCR_3_CS

GRM2 GRM4

4.00e-0414402IPR017979
DomainTIL_dom

MUC5B SSPOP

4.00e-0414402IPR002919
DomainVWFD

MUC5B SSPOP

5.27e-0416402PS51233
DomainVWD

MUC5B SSPOP

5.27e-0416402SM00216
DomainVWF_type-D

MUC5B SSPOP

5.27e-0416402IPR001846
DomainVWD

MUC5B SSPOP

5.27e-0416402PF00094
DomainFurin_repeat

ERBB2 ERBB3

6.70e-0418402IPR006212
DomainCTCK_1

MUC5B SSPOP

6.70e-0418402PS01185
DomainFU

ERBB2 ERBB3

6.70e-0418402SM00261
DomainTyrKc

MET ERBB2 ERBB3

8.80e-0488403SM00219
DomainTyr_kinase_cat_dom

MET ERBB2 ERBB3

8.80e-0488403IPR020635
DomainGPCR_3

GRM2 GRM4

9.15e-0421402IPR000337
DomainG_PROTEIN_RECEP_F3_4

GRM2 GRM4

1.01e-0322402PS50259
Domain7tm_3

GRM2 GRM4

1.01e-0322402PF00003
DomainGPCR_3_C

GRM2 GRM4

1.01e-0322402IPR017978
DomainG_PROTEIN_RECEP_F3_2

GRM2 GRM4

1.01e-0322402PS00980
DomainG_PROTEIN_RECEP_F3_3

GRM2 GRM4

1.01e-0322402PS00981
DomainG_PROTEIN_RECEP_F3_1

GRM2 GRM4

1.01e-0322402PS00979
DomainPROTEIN_KINASE_TYR

MET ERBB2 ERBB3

1.17e-0397403PS00109
DomainTyr_kinase_AS

MET ERBB2 ERBB3

1.17e-0397403IPR008266
DomainCys_knot_C

MUC5B SSPOP

1.30e-0325402IPR006207
DomainCTCK_2

MUC5B SSPOP

1.30e-0325402PS01225
Domain-

MYF6 OLIG3 MYOG

1.63e-031094034.10.280.10
DomainHLH

MYF6 OLIG3 MYOG

1.72e-03111403PF00010
DomainEGF_LAM_2

ATRN MEGF8

1.87e-0330402PS50027
DomainEGF_LAM_1

ATRN MEGF8

1.87e-0330402PS01248
DomainHLH

MYF6 OLIG3 MYOG

1.95e-03116403SM00353
DomainBHLH

MYF6 OLIG3 MYOG

2.00e-03117403PS50888
DomainbHLH_dom

MYF6 OLIG3 MYOG

2.05e-03118403IPR011598
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

MET ERBB2 ERBB3

2.14e-0525313M47934
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

MYF6 LTBP1 LTBP2 ITGB5 MYOG

2.44e-05161315M27871
PathwayREACTOME_GRB7_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

4.66e-055312M26937
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP1 LTBP2 ITGB5

7.11e-0537313M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP1 LTBP2 ITGB5

1.20e-0444313M26969
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

MET ERBB2 ERBB3

1.37e-0446313M239
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP1 LTBP2 ITGB5

1.46e-0447313M646
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

MET ERBB2 ERBB3

2.34e-0455313M47952
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

ERBB2 ERBB3

2.54e-0411312MM15478
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

ERBB2 ERBB3

3.05e-0412312MM14550
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

ERBB2 ERBB3

3.60e-0413312M549
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

ERBB2 ERBB3

3.60e-0413312M27729
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

ERBB2 ERBB3

3.60e-0413312MM15320
PathwayWP_HYPOXIADEPENDENT_DIFFERENTIATION_OF_MYOBLASTS

MYF6 MYOG

3.60e-0413312MM15894
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

4.19e-0414312MM14761
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

4.19e-0414312MM14531
PathwayPID_ERBB_NETWORK_PATHWAY

ERBB2 ERBB3

4.83e-0415312M201
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

ERBB2 ERBB3

4.83e-0415312M27608
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM2 GRM4

4.83e-0415312M39442
PathwayREACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING

MET ERBB2

4.83e-0415312MM15037
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM2 GRM4

4.83e-0415312MM15845
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

5.51e-0416312M570
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

ERBB2 JAG1

5.51e-0416312M47424
PathwayWP_GLIOBLASTOMA_SIGNALING

MET ERBB2 ERBB3

7.85e-0483313M39637
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

MET ERBB2 ERBB3

7.85e-0483313M27163
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY

MET ERBB2 ERBB3

7.85e-0483313M47961
PathwayWP_EGFR_TYROSINE_KINASE_INHIBITOR_RESISTANCE

MET ERBB2 ERBB3

8.13e-0484313M39839
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY

MET ERBB2 ERBB3

9.62e-0489313M47963
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

ERBB2 ERBB3

1.05e-0322312M26929
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY

MET ERBB2 ERBB3

1.06e-0392313M47927
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

LTBP1 LTBP2 ITGB5

1.13e-0394313M1041
PathwayBIOCARTA_HER2_PATHWAY

ERBB2 ERBB3

1.15e-0323312MM1480
PathwayBIOCARTA_HER2_PATHWAY

ERBB2 ERBB3

1.15e-0323312M18719
PathwayREACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING

MET ERBB2

1.25e-0324312M2243
PathwayREACTOME_MYOGENESIS

MYF6 MYOG

1.25e-0324312MM15174
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

LTBP1 LTBP2

1.36e-0325312M39713
PathwayREACTOME_SIGNALING_BY_ERBB2_IN_CANCER

ERBB2 ERBB3

1.47e-0326312M29535
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING

ERBB2 ERBB3

1.47e-0326312MM15501
PathwayREACTOME_TGFBR3_EXPRESSION

MYF6 MYOG

1.71e-0328312M48253
PathwayREACTOME_PI3K_AKT_SIGNALING_IN_CANCER

MET ERBB2 ERBB3

1.77e-03110313M27162
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING

ERBB2 ERBB3

1.83e-0329312M27756
PathwayWP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS

MET ERBB2

1.83e-0329312M39516
PathwayREACTOME_MYOGENESIS

MYF6 MYOG

1.83e-0329312M853
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

MET ERBB2 ERBB3

1.91e-03113313MM14783
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

MET ERBB2 ERBB3

2.17e-03118313M713
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP1 LTBP2

2.23e-0332312MM14854
PathwayWP_MAMMARY_GLAND_DEVELOPMENT_PREGNANCY_AND_LACTATION_STAGE_3_OF_4

ERBB2 ERBB3

2.37e-0333312M39455
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

GRM2 GRM4

2.97e-0337312MM15067
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP1 LTBP2

3.13e-0338312MM14874
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

GRM2 GRM4

3.30e-0339312M793
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP1 LTBP2

3.30e-0339312MM14601
PathwayPID_ERBB2_ERBB3_PATHWAY

ERBB2 ERBB3

4.18e-0344312M175
PathwayREACTOME_SIGNALING_BY_ERBB2

ERBB2 ERBB3

4.18e-0344312MM14520
PathwayWP_ERBB_SIGNALING_PATHWAY

ERBB2 ERBB3

4.56e-0346312MM15950
PathwayREACTOME_SIGNALING_BY_PTK6

ERBB2 ERBB3

4.96e-0348312MM15479
PathwayREACTOME_SIGNALING_BY_TGFBR3

MYF6 MYOG

5.16e-0349312M48250
PathwayREACTOME_SIGNALING_BY_ERBB2

ERBB2 ERBB3

5.37e-0350312M553
PathwayWP_ID_SIGNALING_PATHWAY

MYF6 MYOG

5.37e-0350312MM15817
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

MET ERBB2

5.58e-0351312MM14967
PathwayWP_APOPTOSISRELATED_NETWORK_DUE_TO_ALTERED_NOTCH3_IN_OVARIAN_CANCER

ERBB3 TNFRSF21

6.01e-0353312M39688
PathwayPID_TAP63_PATHWAY

SSPOP JAG1

6.24e-0354312M256
PathwayREACTOME_SIGNALING_BY_PTK6

ERBB2 ERBB3

6.24e-0354312M29742
Pubmed

G-CSF influences mouse skeletal muscle development and regeneration by stimulating myoblast proliferation.

MET MYF6 CSF3R MYOG

4.23e-101043421422169
Pubmed

Essential role of Her3 in two signaling transduction patterns: Her2/Her3 and MET/Her3 in proliferation of human gastric cancer.

MET ERBB2 ERBB3

1.76e-09343325400108
Pubmed

Persistent expression of MNF identifies myogenic stem cells in postnatal muscles.

MET MYF6 MYOG

9.82e-0884339268575
Pubmed

Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells.

MET ERBB2 ERBB3

1.47e-07943323866081
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

MYF6 LTBP1 LTBP2 CSF3R P2RX7 MYOG JAG1

4.26e-0738343719453261
Pubmed

Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo.

MET MYF6 MYOG

1.18e-061743315788460
Pubmed

H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation by heregulin production and activation of HER3.

ERBB2 ERBB3

1.49e-06243220581867
Pubmed

Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers.

ERBB2 ERBB3

1.49e-06243235108525
Pubmed

Role for HER2/neu and HER3 in fulvestrant-resistant breast cancer.

ERBB2 ERBB3

1.49e-06243217203234
Pubmed

Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling.

ERBB2 ERBB3

1.49e-06243222733765
Pubmed

Latent transforming growth factor-β binding proteins (LTBP-1 and LTBP-2) and gingiva keratinization.

LTBP1 LTBP2

1.49e-06243225858550
Pubmed

MET and ERBB2 are coexpressed in ERBB2+ breast cancer and contribute to innate resistance.

MET ERBB2

1.49e-06243223825050
Pubmed

Zinc finger transcription factors designed for bispecific coregulation of ErbB2 and ErbB3 receptors: insights into ErbB receptor biology.

ERBB2 ERBB3

1.49e-06243216199884
Pubmed

Posttranscriptional upregulation of HER3 by HER2 mRNA induces trastuzumab resistance in breast cancer.

ERBB2 ERBB3

1.49e-06243230068375
Pubmed

HER3 protein expression in relation to HER2 positivity in patients with primary colorectal cancer: clinical relevance and prognostic value.

ERBB2 ERBB3

1.49e-06243225739551
Pubmed

Targeting HER2/HER3 co-mutations in metastatic breast cancer: Case reports of exceptional responders to trastuzumab and pertuzumab therapy.

ERBB2 ERBB3

1.49e-06243238441358
Pubmed

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer.

ERBB2 ERBB3

1.49e-06243210205169
Pubmed

In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer.

ERBB2 ERBB3

1.49e-06243221638049
Pubmed

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling.

MET ERBB3

1.49e-06243217463250
Pubmed

Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu.

ERBB2 ERBB3

1.49e-06243217638894
Pubmed

The anti-HER3 antibody in combination with trastuzumab exerts synergistic antitumor activity in HER2-positive gastric cancer.

ERBB2 ERBB3

1.49e-06243227317872
Pubmed

The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation.

ERBB2 ERBB3

1.49e-06243212853564
Pubmed

Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome.

ERBB2 ERBB3

1.49e-06243221709195
Pubmed

Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors.

ERBB2 ERBB3

1.49e-06243212134143
Pubmed

HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells.

MET ERBB2

1.49e-06243229223420
Pubmed

Higher-order association states of cellular ERBB3 probed with photo-cross-linkable aptamers.

ERBB2 ERBB3

1.49e-06243218942860
Pubmed

The role of HER2 and HER3 in HER2-amplified cancers beyond breast cancers.

ERBB2 ERBB3

1.49e-06243233907275
Pubmed

Correlation of HER2, p95HER2 and HER3 expression and treatment outcome of lapatinib plus capecitabine in her2-positive metastatic breast cancer.

ERBB2 ERBB3

1.49e-06243222848366
Pubmed

A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2.

ERBB2 ERBB3

1.49e-06243218056992
Pubmed

HER-2 and HER-3 expression in liver metastases of patients with colorectal cancer.

ERBB2 ERBB3

1.49e-06243225915155
Pubmed

MET activation mediates resistance to lapatinib inhibition of HER2-amplified gastric cancer cells.

MET ERBB2

1.49e-06243222238368
Pubmed

Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients.

ERBB2 ERBB3

1.49e-06243225017122
Pubmed

Pertuzumab counteracts the inhibitory effect of ErbB2 on degradation of ErbB3.

ERBB2 ERBB3

1.49e-06243223698633
Pubmed

The significance of ErbB2/3 in the conversion of induced pluripotent stem cells into cancer stem cells.

ERBB2 ERBB3

1.49e-06243235177646
Pubmed

Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas.

ERBB2 ERBB3

1.49e-0624327538656
Pubmed

Pharmacological targeting of the pseudokinase Her3.

ERBB2 ERBB3

1.49e-06243225326665
Pubmed

Impact of HER2 codon 655 polymorphism and expression of HER2 and HER3 in non small cell lung cancer patients.

ERBB2 ERBB3

1.49e-06243226208475
Pubmed

Met-HER3 crosstalk supports proliferation via MPZL3 in MET-amplified cancer cells.

MET ERBB3

1.49e-06243235249128
Pubmed

Dual Targeting of ERBB2/ERBB3 for the Treatment of SLC3A2-NRG1-Mediated Lung Cancer.

ERBB2 ERBB3

1.49e-06243229959202
Pubmed

HER2 expression as a potential marker for response to therapy targeted to the EGFR.

ERBB2 ERBB3

1.49e-06243216622439
Pubmed

ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival.

ERBB2 ERBB3

1.49e-06243222157714
Pubmed

c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma.

MET ERBB2

1.49e-06243211895493
Pubmed

Genomic profiling of pleomorphic and florid lobular carcinoma in situ reveals highly recurrent ERBB2 and ERRB3 alterations.

ERBB2 ERBB3

1.49e-06243231932682
Pubmed

Early response to ErbB2 over-expression in polarized Caco-2 cells involves partial segregation from ErbB3 by relocalization to the apical surface and initiation of survival signaling.

ERBB2 ERBB3

1.49e-06243220589763
Pubmed

Neuregulin induces the rapid association of focal adhesion kinase with the erbB2-erbB3 receptor complex in schwann cells.

ERBB2 ERBB3

1.49e-06243210799311
Pubmed

c-MET positivity and its relationship with histopathological findings in gastric carcinomas exhibiting HER2 gene expression.

MET ERBB2

1.49e-06243236308181
Pubmed

Spontaneous and pronase-induced HER2 truncation increases the trastuzumab binding capacity of breast cancer tissues and cell lines.

ERBB2 ERBB3

1.49e-06243222806884
Pubmed

Oncogenic ERBB3 mutations in human cancers.

ERBB2 ERBB3

1.49e-06243223680147
Pubmed

Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4.

GRM2 GRM4

1.49e-06243234135510
Pubmed

Correlation analysis of mesenchymal-epithelial transition factor protein and human epidermal growth receptor 2 protein expression in 1479 cases of lung adenocarcinoma in China.

MET ERBB2

1.49e-06243229400000
Pubmed

Carboxyl group footprinting mass spectrometry and molecular dynamics identify key interactions in the HER2-HER3 receptor tyrosine kinase interface.

ERBB2 ERBB3

1.49e-06243223843458
Pubmed

Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity.

ERBB2 ERBB3

1.49e-06243234171264
Pubmed

Design, synthesis and characterization of peptidomimetic conjugate of BODIPY targeting HER2 protein extracellular domain.

ERBB2 ERBB3

1.49e-06243223688700
Pubmed

HER3 intracellular domains play a crucial role in HER3/HER2 dimerization and activation of downstream signaling pathways.

ERBB2 ERBB3

1.49e-06243222983903
Pubmed

HER3 Targeting Sensitizes HNSCC to Cetuximab by Reducing HER3 Activity and HER2/HER3 Dimerization: Evidence from Cell Line and Patient-Derived Xenograft Models.

ERBB2 ERBB3

1.49e-06243227358485
Pubmed

Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.

GRM2 GRM4

1.49e-06243224381270
Pubmed

Anticancer activity of paroxetine in human colon cancer cells: Involvement of MET and ERBB3.

MET ERBB3

1.49e-06243230421568
Pubmed

PC cell-derived growth factor stimulates proliferation and confers Trastuzumab resistance to Her-2-overexpressing breast cancer cells.

ERBB2 GRN

1.49e-06243216857791
Pubmed

Met receptor contributes to trastuzumab resistance of Her2-overexpressing breast cancer cells.

MET ERBB2

1.49e-06243218316611
Pubmed

Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase.

ERBB2 ERBB3

1.49e-06243221385943
Pubmed

CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes.

ERBB2 ERBB3

1.49e-06243228805349
Pubmed

Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association.

ERBB2 ERBB3

1.49e-06243212000754
Pubmed

Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.

ERBB2 ERBB3

1.49e-06243222248472
Pubmed

[Expression of c-erbB-2 and c-met proteins in gastric adenoma and adenocarcinoma].

MET ERBB2

1.49e-06243218172343
Pubmed

Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea.

ERBB2 ERBB3

1.49e-06243212483526
Pubmed

Inhibition of ErbB-2 and ErbB-3 expression by quercetin prevents transforming growth factor alpha (TGF-alpha)- and epidermal growth factor (EGF)-induced human PC-3 prostate cancer cell proliferation.

ERBB2 ERBB3

1.49e-06243212888923
Pubmed

Overexpression and gene amplification of EGFR, HER2, and HER3 in biliary tract carcinomas, and the possibility for therapy with the HER2-targeting antibody pertuzumab.

ERBB2 ERBB3

1.49e-06243225112701
Pubmed

Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016.

ERBB2 ERBB3

1.49e-06243214737100
Pubmed

Expression of mutant human epidermal receptor 3 attenuates lung fibrosis and improves survival in mice.

ERBB2 ERBB3

1.49e-06243215731393
Pubmed

Overexpression of ErbB2 and ErbB3 receptors in Schwann cells of patients with Charcot-Marie-tooth disease type 1A.

ERBB2 ERBB3

1.49e-06243216307437
Pubmed

Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.

ERBB2 ERBB3

1.49e-06243216168116
Pubmed

Increased erbB3 promotes erbB2/neu-driven mammary tumor proliferation and co-targeting of erbB2/erbB3 receptors exhibits potent inhibitory effects on breast cancer cells.

ERBB2 ERBB3

1.49e-06243226261492
Pubmed

Mechanistic Investigations of Diarrhea Toxicity Induced by Anti-HER2/3 Combination Therapy.

ERBB2 ERBB3

1.49e-06243229654069
Pubmed

Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.

ERBB2 ERBB3

1.49e-06243229338072
Pubmed

Engineering of a bispecific affibody molecule towards HER2 and HER3 by addition of an albumin-binding domain allows for affinity purification and in vivo half-life extension.

ERBB2 ERBB3

1.49e-06243224678002
Pubmed

HER family receptor abnormalities in lung cancer brain metastases and corresponding primary tumors.

ERBB2 ERBB3

1.49e-06243219622585
Pubmed

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies.

ERBB2 ERBB3

1.49e-06243226138066
Pubmed

Identification of patients with transitional cell carcinoma of the bladder overexpressing ErbB2, ErbB3, or specific ErbB4 isoforms: real-time reverse transcription-PCR analysis in estimation of ErbB receptor status from cancer patients.

ERBB2 ERBB3

1.49e-06243214614020
Pubmed

NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies.

ERBB2 ERBB3

4.48e-06343226770651
Pubmed

EGFR, HER2, and HER3 protein expression in paired primary tumor and lymph node metastasis of colorectal cancer.

ERBB2 ERBB3

4.48e-06343235902718
Pubmed

[Correlation of epidermal growth factor receptor mutations and HER2/3 protein expression with clinical outcome in advanced non-small cell lung cancer patients treated with gefitinib].

ERBB2 ERBB3

4.48e-06343220038315
Pubmed

Relation between transforming growth factor-β1 expression, its receptor and clinicopathological factors and survival in HER2-negative gastric cancers.

ERBB2 LTBP1

4.48e-06343222015652
Pubmed

Growth stimulation of non-small cell lung cancer cell lines by antibody against epidermal growth factor receptor promoting formation of ErbB2/ErbB3 heterodimers.

ERBB2 ERBB3

4.48e-06343217426253
Pubmed

Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1, 2 and 3 in Periampullary Adenocarcinoma.

ERBB2 ERBB3

4.48e-06343227070783
Pubmed

HER2 regulates cancer stem-like cell phenotype in ALK translocated NSCLC.

ERBB2 ERBB3

4.48e-06343228656214
Pubmed

Specific antibodies and sensitive immunoassays for the human epidermal growth factor receptors (HER2, HER3, and HER4).

ERBB2 ERBB3

4.48e-06343228653892
Pubmed

FOXO1 Suppression is a Determinant of Acquired Lapatinib-Resistance in HER2-Positive Gastric Cancer Cells Through MET Upregulation.

MET ERBB2

4.48e-06343228343375
Pubmed

Role of HER3 expression and PTEN loss in patients with HER2-overexpressing metastatic breast cancer (MBC) who received taxane plus trastuzumab treatment.

ERBB2 ERBB3

4.48e-06343224346286
Pubmed

A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy.

ERBB2 ERBB3

4.48e-06343218632642
Pubmed

Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer.

ERBB2 ERBB3

4.48e-06343225471734
Pubmed

EGFR/ERBB receptors differentially modulate sebaceous lipogenesis.

ERBB2 ERBB3

4.48e-06343225889637
Pubmed

The immunoexpression of EGFR, HER2 and HER3 in malignant serous ovarian tumors.

ERBB2 ERBB3

4.48e-06343229556616
Pubmed

FGFR2, HER2 and cMet in gastric adenocarcinoma: detection, prognostic significance and assessment of downstream pathway activation.

MET ERBB2

4.48e-06343224306956
Pubmed

WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling.

ERBB2 ERBB3

4.48e-06343226804171
Pubmed

Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein.

ERBB2 TREML4

4.48e-06343222210914
Pubmed

Mechanisms of resistance to third-generation EGFR tyrosine kinase inhibitors.

MET ERBB2

4.48e-06343227770386
Pubmed

Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers.

MET ERBB2

4.48e-06343223470965
Pubmed

The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination.

ERBB2 ERBB3

4.48e-06343222262199
Pubmed

Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3.

ERBB2 ERBB3

4.48e-0634327592681
Pubmed

Neuregulin-1-mediated ErbB2-ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiation.

ERBB2 ERBB3

4.48e-06343226490994
InteractionLYPD1 interactions

ATRN GBF1 MEGF8 ITGB5

5.22e-0658404int:LYPD1
InteractionSHD interactions

MET ERBB2 ERBB3

5.79e-0618403int:SHD
InteractionSHC4 interactions

MET ERBB2 ERBB3

1.09e-0522403int:SHC4
InteractionSLA2 interactions

MET ERBB2 ERBB3

1.42e-0524403int:SLA2
InteractionSOCS5 interactions

MET ERBB2 ERBB3

1.42e-0524403int:SOCS5
InteractionSH2B3 interactions

MET ERBB2 ERBB3

1.62e-0525403int:SH2B3
InteractionHSH2D interactions

MET ERBB2 ERBB3

1.62e-0525403int:HSH2D
InteractionSTAP1 interactions

MET ERBB2 ERBB3

2.05e-0527403int:STAP1
InteractionATN1 interactions

GRN OLIG3 LTBP1 MEGF8 SSPOP

3.30e-05187405int:ATN1
InteractionSH2D1B interactions

MET ERBB2 ERBB3

3.45e-0532403int:SH2D1B
InteractionSH2B1 interactions

MET ERBB2 ERBB3

3.45e-0532403int:SH2B1
InteractionSOCS3 interactions

MET ERBB2 ERBB3 CSF3R

6.60e-05110404int:SOCS3
InteractionTNS1 interactions

MET ERBB2 ERBB3

7.33e-0541403int:TNS1
InteractionSHC1 interactions

MET ERBB2 GRN ERBB3 GBF1 CSF3R

7.38e-05362406int:SHC1
InteractionSOS1 interactions

PRICKLE2 MET ERBB2 ERBB3

8.39e-05117404int:SOS1
InteractionMATK interactions

MET ERBB2 ERBB3

8.46e-0543403int:MATK
InteractionSHC2 interactions

MET ERBB2 ERBB3

9.07e-0544403int:SHC2
InteractionSH2D1A interactions

MET ERBB2 ERBB3

9.70e-0545403int:SH2D1A
InteractionTMA7 interactions

ERBB2 ERBB3 GVINP1

1.04e-0446403int:TMA7
InteractionSH3BP2 interactions

MET ERBB2 ERBB3

1.18e-0448403int:SH3BP2
InteractionMUC4 interactions

ERBB2 ERBB3

1.37e-049402int:MUC4
InteractionFBXO2 interactions

ATRN MET GRN MEGF8 ITGB5 JAG1

1.48e-04411406int:FBXO2
InteractionSH2D2A interactions

MET ERBB2 ERBB3

1.50e-0452403int:SH2D2A
InteractionVAV3 interactions

MET ERBB2 ERBB3

1.77e-0455403int:VAV3
InteractionSLURP1 interactions

ATRN MET GRN MEGF8

1.87e-04144404int:SLURP1
InteractionZNF408 interactions

ATRN GRN LTBP1 LTBP2

1.92e-04145404int:ZNF408
InteractionTXK interactions

MET ERBB2 ERBB3

1.97e-0457403int:TXK
InteractionCDCA7 interactions

CDCA7 CDCA7L

2.09e-0411402int:CDCA7
InteractionFES interactions

MET ERBB2 ERBB3

2.41e-0461403int:FES
InteractionBTNL2 interactions

ATRN MET MEGF8 ITGB5

2.48e-04155404int:BTNL2
InteractionITK interactions

MET ERBB2 ERBB3

2.53e-0462403int:ITK
InteractionLRIG1 interactions

MET ERBB2 ERBB3

2.65e-0463403int:LRIG1
InteractionBCAR3 interactions

MET ERBB2 ERBB3

3.04e-0466403int:BCAR3
InteractionJAK2 interactions

ERBB2 ERBB3 MUC5B CSF3R

3.15e-04165404int:JAK2
InteractionSMIM20 interactions

ERBB2 ERBB3

3.44e-0414402int:SMIM20
InteractionSHC3 interactions

MET ERBB2 ERBB3

3.93e-0472403int:SHC3
InteractionASIP interactions

ATRN GRN

4.53e-0416402int:ASIP
InteractionFBXO6 interactions

ATRN MET GRN MUC5B LTBP1 MEGF8 ITGB5

4.69e-04717407int:FBXO6
InteractionLGALS1 interactions

ATRN MET GRN ITGB5 JAG1

4.83e-04332405int:LGALS1
InteractionTMEM134 interactions

ERBB2 ERBB3

5.13e-0417402int:TMEM134
InteractionCALM3 interactions

MET MYF6 ERBB2 ERBB3 MYOG

5.60e-04343405int:CALM3
InteractionHCK interactions

MET ERBB2 ERBB3 CSF3R

5.69e-04193404int:HCK
InteractionSHB interactions

MET ERBB2 ERBB3

6.17e-0484403int:SHB
InteractionNAALADL2 interactions

ERBB2 GRM2

6.43e-0419402int:NAALADL2
InteractionHOXA1 interactions

GRN LTBP1 MEGF8 ZNRF3 RGS19

6.62e-04356405int:HOXA1
InteractionTNS3 interactions

MET ERBB2 ERBB3

6.84e-0487403int:TNS3
InteractionTXN interactions

MET ERBB2 GRN ERBB3 GRM2

6.96e-04360405int:TXN
InteractionTEC interactions

MET ERBB2 ERBB3

7.55e-0490403int:TEC
InteractionPTPN11 interactions

MET ERBB2 ERBB3 GBF1 CSF3R

7.69e-04368405int:PTPN11
InteractionZAP70 interactions

MET ERBB2 ERBB3

8.05e-0492403int:ZAP70
InteractionFGR interactions

MET ERBB2 ERBB3

8.31e-0493403int:FGR
InteractionHSD17B12 interactions

ILDR2 MET ERBB2 GRM2

9.28e-04220404int:HSD17B12
InteractionID4 interactions

MYF6 MYOG

9.47e-0423402int:ID4
InteractionSFTPC interactions

ATRN MET MEGF8 SCARF2

9.60e-04222404int:SFTPC
InteractionSEC61A1 interactions

MET ERBB2 GBF1 GRM2

9.76e-04223404int:SEC61A1
InteractionVAV2 interactions

MET ERBB2 ERBB3

9.96e-0499403int:VAV2
InteractionPLCG2 interactions

MET ERBB2 ERBB3

1.03e-03100403int:PLCG2
InteractionDUSP18 interactions

ERBB2 ERBB3

1.03e-0324402int:DUSP18
InteractionCSRP3 interactions

MYF6 MYOG

1.03e-0324402int:CSRP3
InteractionCRKL interactions

ERBB2 GRN ERBB3 GBF1

1.04e-03227404int:CRKL
InteractionVAV1 interactions

PRICKLE2 MET ERBB2 ERBB3

1.06e-03228404int:VAV1
InteractionPIK3R2 interactions

MET ERBB2 GRN ERBB3

1.09e-03230404int:PIK3R2
InteractionRNF133 interactions

GBF1 RNF133

1.12e-0325402int:RNF133
InteractionPTK6 interactions

MET ERBB2 ERBB3

1.15e-03104403int:PTK6
InteractionKDELR2 interactions

MET ERBB2 GBF1

1.15e-03104403int:KDELR2
InteractionTNS2 interactions

MET ERBB2 ERBB3 ITGB5

1.18e-03235404int:TNS2
InteractionCLGN interactions

MET ERBB2 ERBB3 GRM2

1.18e-03235404int:CLGN
InteractionGNA15 interactions

GRM2 GRM4

1.21e-0326402int:GNA15
InteractionDAB1 interactions

ERBB2 ERBB3 ITGB5

1.25e-03107403int:DAB1
InteractionABL2 interactions

MET ERBB2 ERBB3

1.25e-03107403int:ABL2
InteractionZNF532 interactions

ERBB2 ERBB3

1.31e-0327402int:ZNF532
InteractionNCK1 interactions

MET ERBB2 ERBB3 SCARF2

1.36e-03244404int:NCK1
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP1 LTBP2

1.59e-054302628
GeneFamilyErb-b2 receptor tyrosine kinases

ERBB2 ERBB3

1.59e-0543021096
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM2 GRM4

7.41e-058302281
GeneFamilyBasic helix-loop-helix proteins

MYF6 OLIG3 MYOG

7.89e-04110303420
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ERBB2 CSF3R TNFRSF21 JAG1

3.89e-03394304471
CoexpressionGSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN

ATRN GRN GBF1 MEGF8 RGS19

1.87e-05200435M5977
CoexpressionGSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_UP

GRN ZNFX1 ERBB3 CSF3R ITGB5

1.87e-05200435M8209
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL

GOLGA8B MET ERBB2 LTBP2 ITGB5 JAG1

2.36e-05355436M45758
CoexpressionPEDRIOLI_MIR31_TARGETS_DN

KIAA0040 ARSD CSF3R GVINP1 P2RX7 SCARF2

5.49e-05413436M2494
CoexpressionAtlasMyeloid Cells, Mo.6C+II-.BM, B220neg CD3neg CD115+ Ly-6C+, Bone marrow, avg-3

MET GRN TREML4 CSF3R CDCA7 TNFRSF21 ITGB5

1.24e-05391437GSM854329_500
CoexpressionAtlasMyeloid Cells, MF.Lv, CD45+ F4/80+ CD11b+, Liver, avg-2

MET GRN TREML4 CSF3R TNFRSF21 ITGB5

1.50e-04402436GSM854320_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

MET KIAA0040 LTBP1 ZNRF3 CDCA7 TNFRSF21 CDCA7L JAG1

1.52e-04783438gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlasB cells, MLP.BM, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R- CD, Bone marrow, avg-2

MET CSF3R CDCA7 TNFRSF21 ITGB5 CDCA7L

1.54e-04404436GSM791129_500
CoexpressionAtlasMyeloid Cells, Mo.6C+II+.Bl, CD115+ B220- CD43+ Ly6C+ MHCIIint, Blood, avg-4

MET GRN TREML4 CSF3R TNFRSF21 ITGB5

1.62e-04408436GSM605868_500
CoexpressionAtlasMyeloid Cells, Mo.6C-II-.BM, B220neg CD3neg CD115+ Ly-6C/Glo CD43+, Bone marrow, avg-3

GRN TREML4 CSF3R CDCA7 TNFRSF21 ITGB5

1.64e-04409436GSM854332_500
CoexpressionAtlasMyeloid Cells, Mo.6C+II-.Bl, Cd115+ B220- CD43+ Ly6C+ MHCII-, Blood, avg-3

MET GRN TREML4 CSF3R TNFRSF21 ITGB5

1.69e-04411436GSM605872_500
CoexpressionAtlasMyeloid Cells, Mo.6C-II+.Bl, CD115+ B220- CD43+ Ly6C- MHCIIhi, Blood, avg-2

MET GRN TREML4 CSF3R TNFRSF21 ITGB5

1.73e-04413436GSM605878_500
CoexpressionAtlasB cells, MLP.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R- CD117+ IL7R-, Bone marrow, avg-2

MET CSF3R CDCA7 TNFRSF21 ITGB5 CDCA7L

1.95e-04422436GSM791124_500
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MET ERBB2 ERBB3 MUC5B GRM4

1.22e-06195435b9e8f405f6d837bb39b615836d3e2df349737c0e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Astrocyte|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ERBB3 BRINP3 LTBP1 P2RX7 CDCA7L

1.39e-062004354fe3b2d80c567c18621bff3341f9a73578c81621
ToppCelldroplet-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MT4 ERBB3 TREML4 TNFRSF21

1.10e-051434344d11d53330a9197275a8851e1bbf55a113715a09
ToppCelldroplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MT4 ERBB3 TREML4 TNFRSF21

1.10e-051434348b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MET ERBB3 MUC5B NALF2

1.22e-05147434aba44c7057096483c4293a7ebcf8ccc8baed0231
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 TREML4 CSF3R TNFRSF21

1.62e-05158434b0508a600994090c6aafd8d779437190a33ad821
ToppCellfacs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 TREML4 CSF3R TNFRSF21

1.62e-05158434a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 CSF3R TNFRSF21 ITGB5

2.07e-05168434f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 CSF3R TNFRSF21 ITGB5

2.16e-051704347cb7ad9ab064b6ea452545d145e5b1d4090cd4c1
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 CSF3R TNFRSF21 ITGB5

2.16e-05170434db7cee7e518debb2cbe9eeae05d47e14b69cb8e3
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ERBB3 MUC5B GRM4 NALF2

2.32e-05173434d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-new-cluster|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 TREML4 CSF3R RGS19

2.37e-05174434718e14d9a4264456459bec4c062c94c3a848d43a
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 TREML4 CSF3R RGS19

2.42e-0517543461fdafba120fbda063d4dc05263d6f8d1dcab1e1
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 TREML4 CSF3R RGS19

2.42e-051754348de8031fdf2af187642833feb80caa64932897cf
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ILDR2 BRINP3 LTBP1 LTBP2

2.77e-05181434b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCelldroplet-Thymus-nan-18m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET ERBB2 GRN MEGF8

2.83e-05182434f6717e97e87513384149800c9fd8dea821ab9393
ToppCelldroplet-Thymus-nan-18m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET ERBB2 GRN MEGF8

2.83e-05182434c33b0d532822186a1e8e645500347972468718c0
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ILDR2 MET BRINP3 GRM4

3.01e-051854345a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast|bone_marrow / Manually curated celltypes from each tissue

PRICKLE2 LTBP1 WDR90 CDCA7

3.01e-05185434a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP2 SCARF2 ITGB5 JAG1

3.08e-051864344e983de6d2515082f9e555f4f949cec84281c140
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

PRICKLE2 LTBP1 TNFRSF21 ITGB5

3.21e-051884348231e635706a296db6b6da1029a33bbc1b52478e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BRINP3 LTBP1 LTBP2 JAG1

3.21e-051884343004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellNon-neuronal-Non-dividing-OPC-OPC|World / Primary Cells by Cluster

ERBB3 BRINP3 P2RX7 CDCA7L

3.27e-05189434ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCellNon-neuronal-Non-dividing-OPC|World / Primary Cells by Cluster

ERBB3 BRINP3 P2RX7 CDCA7L

3.27e-0518943413848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCellNon-neuronal-Non-dividing-OPC-OPC-30|World / Primary Cells by Cluster

ERBB3 BRINP3 P2RX7 CDCA7L

3.27e-05189434313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCellBL-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MET ERBB2 ERBB3 MUC5B

3.34e-05190434f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ILDR2 MET BRINP3 GRM4

3.34e-051904341bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 BRINP3 ZNRF3 CDCA7

3.41e-05191434a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZNRF3 CDCA7 ITGB5 JAG1

3.48e-05192434c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ILDR2 MET BRINP3 GRM4

3.48e-0519243425460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

PRICKLE2 BRINP3 LTBP1 LTBP2

3.55e-05193434e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellClub_cells|World / lung cells shred on cell class, cell subclass, sample id

MET ERBB2 ERBB3 MUC5B

3.55e-051934349d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRN CSF3R TNFRSF21 ITGB5

3.63e-051944348e2819a9d0529f7b2de1a7c1190575175d6173ee
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIAA0040 ZNFX1 TREML4 CSF3R

3.63e-05194434267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

GRN LTBP2 CSF3R ITGB5

3.70e-0519543410fa47bdcf6c9784ea930b75a5861e139421feed
ToppCellNS-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MET ERBB2 ERBB3 MUC5B

3.70e-05195434b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MET ERBB2 ERBB3 MUC5B

3.85e-05197434a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCelltumor_Lung-Fibroblasts-Myofibroblasts|tumor_Lung / Location, Cell class and cell subclass

LTBP1 LTBP2 SCARF2 ITGB5

3.93e-0519843431f9181dab689aabe9c6182c2ef7de65ba3f0ff6
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+_SCGB1A1+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MET ERBB2 ERBB3 MUC5B

3.93e-05198434a3d4b6e4259ded2193d94d2ff6d48cf67214fc35
ToppCellNon-neuronal-Dividing-IPC-IPC-new|World / Primary Cells by Cluster

LTBP1 CDCA7 CDCA7L JAG1

3.93e-0519843411d2d4d179bc31ef2897d7ceeaf9bed1b20cbdc0
ToppCellNon-neuronal-Dividing-IPC-IPC-new-9|World / Primary Cells by Cluster

LTBP1 CDCA7 CDCA7L JAG1

3.93e-05198434c724ef958e14e17a7d8c02b9f842510c0780f635
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB2 ERBB3 ZNRF3 CDCA7

3.93e-05198434e8bfae3888b2406b5629b576cb02913b3297337e
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MET ERBB2 ERBB3 MUC5B

4.00e-05199434a8bfc0b93ad9968cf52a25be86995ffe436bd636
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRN TREML4 CSF3R P2RX7

4.00e-0519943498c0d57c247d39bc771d81f4387f8dd01222628e
ToppCellmedial-2-mesenchymal-Myofibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRINP3 LTBP1 LTBP2 SCARF2

4.00e-0519943495aae608fa35a9c82b12c6f18937ce636750ca44
ToppCelltumor_Lung-Epithelial_cells-tS2|tumor_Lung / Location, Cell class and cell subclass

MET ERBB2 ERBB3 TNFRSF21

4.00e-0519943428ec59e01061287fb0892491790b316e2b93e232
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GRN TREML4 CSF3R P2RX7

4.00e-05199434b818d46a39c8782188d82dc8931b8eec9d549dd1
ToppCellmedial-mesenchymal-Myofibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRINP3 LTBP1 LTBP2 SCARF2

4.00e-05199434e25acdb5809aaff631cb06dbe4c7e59549a0bdb9
ToppCellmedial-mesenchymal-Myofibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRINP3 LTBP1 LTBP2 SCARF2

4.00e-051994349ebf4822ff9fa08574edec5dbf4f2a1488f34b1d
ToppCellSigmoid-Macrophage-Macrophage|Sigmoid / Region, Cell class and subclass

GRN CSF3R TNFRSF21 ITGB5

4.08e-052004349ee3a799de7bade1bfe94b6827461633f02bc1dc
ToppCellSigmoid-Macrophage|Sigmoid / Region, Cell class and subclass

GRN CSF3R TNFRSF21 ITGB5

4.08e-05200434b07ac0ff3b8530e99094678fed80f35949cafac8
ToppCellSigmoid-(6)_Macrophage-(60)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

GRN CSF3R TNFRSF21 ITGB5

4.08e-05200434ad84a83a5a1893f7b053d39eddeca851463a8ff0
ToppCellSigmoid-(6)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

GRN CSF3R TNFRSF21 ITGB5

4.08e-052004349e10cca4429de2c4c8c3c6cf2c9e28637a095be9
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Ctps_(Ctps)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ERBB3 SSPOP TSPAN10

9.01e-05904334d75217fd6b376bfda3300962cbe4875b31ffdaf
ToppCellEndothelial-Endothelial-F|Endothelial / shred on cell class and cell subclass (v4)

ERBB2 ZNFX1 GVINP1

2.22e-041224332cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf|Hippocampus / BrainAtlas - Mouse McCarroll V32

ERBB3 SSPOP TSPAN10

2.80e-04132433dc6edfa821a1cdc645668b0af5ba5ff80dee10bd
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2|Hippocampus / BrainAtlas - Mouse McCarroll V32

ERBB3 SSPOP TSPAN10

2.80e-0413243360ced08bda5efc95a6f116cd0c6d1a779d99ed38
ToppCellCOVID-19_Moderate-B_cell|World / disease group, cell group and cell class

ERBB3 LTBP2 GRM2

3.25e-04139433b93e1da87d44e55d75e8cc1b87c2970645679c01
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ILDR2 MUC5B CSF3R

3.99e-04149433c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ILDR2 MUC5B CSF3R

3.99e-04149433a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TREML4 CSF3R TNFRSF21

4.06e-04150433b37f538ca5f976b509efe35dc81115b72b227084
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TREML4 CSF3R TNFRSF21

4.06e-041504332c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ERBB3 MUC5B NALF2

4.23e-0415243300d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 LTBP1 JAG1

4.31e-041534330ef7c45cdd854c79e527006034029767f8e108b2
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ILDR2 ERBB3 BRINP3

4.47e-041554335fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ILDR2 BRINP3 LTBP1

4.47e-04155433cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 GOLGA8B MET

4.64e-041574336ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellfacs-Marrow-B-cells-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 TREML4 TSPAN10

4.64e-041574330966e347f8d32b13f8a3b3afba3f64637c69cdf9
ToppCellfacs-Marrow-B-cells-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 TREML4 TSPAN10

4.64e-041574336ebfedd91d62c6d4aa8f046657a899a279f82ba2
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma|TCGA-Bladder / Sample_Type by Project: Shred V9

ERBB3 TNFRSF21 FER1L4

4.73e-04158433dc559503bab3ec1b9ea54ef2e896d1be33e5344c
ToppCellClub_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MET ERBB2 ERBB3

4.82e-04159433a7bcff268b1962a561fd2848e01ae16565bce895
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GVINP1 CDCA7 CDCA7L

4.82e-0415943395128a2367ff2a639b21913c0350924c174faef8
ToppCelldroplet-Limb_Muscle-nan-24m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF3R CDCA7 CDCA7L

4.82e-0415943339033d49501a4ecc00af6c256e7a569c903ad332
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

MET WDR90 FER1L4

4.82e-04159433655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellfacs-Lung-Endomucin-24m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 CSF3R TSPAN10

4.82e-04159433886cbaef39a3517514a3896b6b960d01a3af043d
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC5B ZNRF3 CDCA7

4.91e-041604336005948e400e781cdb876ba350b3ec8991e3945f
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MET ERBB3 MUC5B

5.00e-041614332d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MET GRM2 NALF2

5.00e-04161433ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellMyeloid|World / shred on cell class and cell subclass (v4)

GRN CSF3R GVINP1

5.00e-04161433aee407d3739dba2d5216dcdb1579e7e4f483123d
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Club_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ERBB2 MUC5B FER1L4

5.09e-04162433aed15eef32419b8a4e2afdb9776c2bf2802e96f1
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ERBB2 LTBP2 ITGB5

5.27e-04164433d7053de88ef8e42cac6726a40e72f212659ee034
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BRINP3 LTBP1 LTBP2

5.27e-04164433e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP1 CDCA7 JAG1

5.37e-041654334f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellfacs-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 CSF3R TNFRSF21

5.37e-04165433720649f330382ea2a68c64a5344160a048afb8f1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP1 CDCA7 JAG1

5.37e-04165433cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 MET ERBB3

5.46e-04166433c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCelldroplet-Lung-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TREML4 CSF3R TNFRSF21

5.56e-041674336f6f654d10cff83203415685f7707409626990ab
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

LTBP1 LTBP2 ITGB5

5.56e-04167433d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCelldroplet-Lung-nan-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF3R TNFRSF21 RGS19

5.66e-04168433da1eee804456d910c17f145a5ce79c74a808a2c2
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET GVINP1 P2RX7

5.66e-041684332e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MET GRN TNFRSF21

5.75e-04169433a0681317867e31319210a23e56660a53f4529efe
ToppCelldroplet-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 TNFRSF21 ITGB5

5.75e-0416943391cfff1ad559cc327c6bb71c98aa29f0b3642568
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRN TREML4 ITGB5

5.75e-0416943344d841fd997a6f26104f16cd00223ecce8352f43
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MET BRINP3 MUC5B

5.75e-04169433a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRN TREML4 ITGB5

5.75e-041694330f5e737b265ba333275a0cd289dab029a1542075
ToppCelldroplet-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 TNFRSF21 ITGB5

5.75e-041694338e5e513090e86ca29fb61dfd388014774c506914
ToppCelldroplet-Thymus-nan-18m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET ERBB2 MEGF8

5.75e-041694334ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MET ERBB2 MUC5B

5.75e-04169433aec97583b23112060437b619cb429dc32f29285f
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRN TREML4 ITGB5

5.75e-04169433aec1b4c7e973a31c53aaea47c2c05d24ce16aa4f
ToppCelldroplet-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 TNFRSF21 ITGB5

5.75e-04169433972618e684321060c7af2429f853a6d639e8aae8
ComputationalPlacenta genes.

ERBB2 GRN ERBB3 LTBP1 LTBP2 CSF3R ITGB5 JAG1

3.66e-05463318MODULE_38
ComputationalPorins / transporters.

ERBB2 CSF3R P2RX7 TNFRSF21 ITGB5

3.12e-04211315MODULE_63
ComputationalMembranal receptors.

GRN GRM2 CSF3R P2RX7 TNFRSF21 ITGB5 JAG1

5.48e-04517317MODULE_64
DrugNVP-TAE684

MET ERBB2 ERBB3

2.81e-0615433ctd:C516714
Drugenzacamene

MET ERBB2 ERBB3 ITGB5 JAG1

4.37e-06129435ctd:C038939
Drugoctylmethoxycinnamate

MET ERBB2 ERBB3 ITGB5 JAG1

6.30e-06139435ctd:C118580
Drug2-acetamidoethanethiol

ERBB2 ERBB3

1.04e-053432ctd:C023704
DrugPHA665752

MET ERBB2 ERBB3

1.08e-0523433CID010461815
Drugbenzylidenemalononitrile

ERBB2 GRN ERBB3

1.78e-0527433CID000017608
DrugCbpg

GRM2 GRM4

2.09e-054432CID005311040
DrugpM47

MT4 NALF2

2.09e-054432CID006334622
Drugaurintricarboxylic acid

MT4 GRM2 GRM4 RGS19

2.62e-0591434CID000002259
DrugN-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; HL60; HT_HG-U133A

ATRN GBF1 CSF3R TNFRSF21 ITGB5

3.32e-051964353085_DN
DrugGlimepiride [93479-97-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A

ERBB2 GRN TNFRSF21 RGS19 JAG1

3.48e-051984352809_DN
DrugAC1MBZ3L

GRM2 GRM4

5.20e-056432CID002733524
DrugZD-6

ERBB2 ERBB3

5.20e-056432CID010062753
Drugcyclizine

OLIG3 ERBB3 GRM2 GRM4

6.77e-05116434CID000006726
DrugAC1L1JJ0

ERBB2 JAG1

7.27e-057432CID000005061
DrugEGFR inhibitor

MET ERBB2 ERBB3 JAG1

7.73e-05120434CID009549299
DrugLSOs

GRN GRM2 GRM4 RSF1

8.78e-05124434CID000164701
Drugcis-MCG-I

GRM2 GRM4

9.69e-058432CID003035584
DrugFolfox protocol

ERBB2 ERBB3

9.69e-058432ctd:C410216
DrugAC1MPLNZ

ERBB2 MT4

9.69e-058432CID003387239
DrugPKI166

MET ERBB2 ERBB3

1.02e-0448433CID006918403
Drugphorbol 12,13-diacetate

MT4 GRM2 GRM4

1.02e-0448433CID000072293
DrugAC1LD7MJ

MT4 GRM2 GRM4

1.09e-0449433CID000643628
DrugAC1N21PP

GRM2 GRM4

1.24e-049432CID004014619
DrugAC1L18E1

MYF6 MYOG

1.24e-049432CID000000060
Drug1,3-cyclopentanedicarboxylic acid

GRM2 GRM4

1.24e-049432CID000107216
DrugmM PEP

GRM2 GRM4

1.24e-049432CID005311462
DrugSu-M

ERBB2 GRN ERBB3

1.30e-0452433CID000446388
Drugsakyomicin A

MYF6 MT4 MYOG

1.46e-0454433CID000124041
Drug6-(methylamino)pyrido(3,4-d)pyrimidine

ERBB2 ERBB3

1.55e-0410432ctd:C107875
DrugNS-105

GRM2 GRM4

1.55e-0410432CID000198695
Drug2-[amino-[(2R,3R)-4-(benzylamino)-3-hydroxy-4-oxo-2-sulfanylbutanoyl]amino]acetic acid

MYF6 MYOG

1.90e-0411432CID016122531
DrugBE-23372M

ERBB2 ERBB3

1.90e-0411432CID005311105
Drugcyclobutylene AP5

GRM2 GRM4

1.90e-0411432CID000126582
Drugbutylparaben

MET ERBB2 ERBB3 JAG1

2.18e-04157434ctd:C038091
Drug2-[amino-[(2R,3R)-4-benzoxy-3-hydroxy-4-keto-2-mercapto-butanoyl]amino]acetic acid

MYF6 MYOG

2.27e-0412432CID016122530
Drugpyridone

MT4 P2RX7

2.27e-0412432CID000008871
Drughomocysteic acid

GRN GRM2 GRM4

2.64e-0466433CID000092117
DrugAC1NSKBB

GRM2 GRM4

2.68e-0413432CID005311256
DrugCMF regimen

ERBB2 ERBB3

2.68e-0413432ctd:C034456
DrugCpd1g-0

MYF6 MYOG

2.68e-0413432CID000000577
DrugMspg

GRM2 GRM4

2.68e-0413432CID003964410
DrugMSOPPE

GRM2 GRM4

2.68e-0413432CID005311463
DiseaseBenign neoplasm of stomach

MET ERBB2 ERBB3

1.80e-0617423C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

MET ERBB2 ERBB3

1.80e-0617423C0496905
DiseaseCarcinoma in situ of stomach

MET ERBB2 ERBB3

1.80e-0617423C0154060
DiseaseStomach Carcinoma

MET ERBB2 ERBB3

3.50e-0621423C0699791
DiseaseEpilepsy, Benign Psychomotor, Childhood

GRM2 GRM4 P2RX7

4.66e-0623423C0393672
DiseaseEpilepsy, Lateral Temporal

GRM2 GRM4 P2RX7

4.66e-0623423C0393682
DiseaseUncinate Epilepsy

GRM2 GRM4 P2RX7

4.66e-0623423C0014558
DiseaseEpilepsy, Temporal Lobe

GRM2 GRM4 P2RX7

4.66e-0623423C0014556
Diseasetongue squamous cell carcinoma (is_marker_for)

MET ERBB3 BRINP3

2.01e-0537423DOID:0050865 (is_marker_for)
DiseaseHead and Neck Carcinoma

ERBB2 ERBB3

8.84e-0510422C3887461
Diseasegallbladder neoplasm

ERBB2 ERBB3

1.08e-0411422C0016978
DiseaseMalignant neoplasm of gallbladder

ERBB2 ERBB3

1.08e-0411422C0153452
Diseasepulse pressure measurement

MET LTBP1 LTBP2 MEGF8 GRM4 CDCA7 SSPOP ITGB5 JAG1

1.23e-041392429EFO_0005763
Diseasemedian neuropathy (biomarker_via_orthology)

ERBB2 ERBB3

1.78e-0414422DOID:571 (biomarker_via_orthology)
Diseasedilated cardiomyopathy (implicated_via_orthology)

ERBB2 LTBP2 JAG1

2.04e-0480423DOID:12930 (implicated_via_orthology)
DiseaseNerve Degeneration

ATRN GRN GRM4

2.28e-0483423C0027746
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB2 ERBB3

3.33e-0419422DOID:2876 (is_marker_for)
DiseaseAdenocarcinoma of large intestine

MET ERBB2 ZNRF3

3.49e-0496423C1319315
Diseaseanti-Mullerian hormone measurement

ZNRF3 CDCA7

3.70e-0420422EFO_0004769
DiseaseNasopharyngeal carcinoma

ERBB2 ERBB3

4.49e-0422422C2931822
DiseaseNeoplasm of the genitourinary tract

MET ERBB2

5.35e-0424422cv:C0042065
Diseasestomach carcinoma (is_marker_for)

ERBB2 ERBB3

5.35e-0424422DOID:5517 (is_marker_for)
DiseaseLung Neoplasms

MET ERBB2 ERBB3 JAG1

5.44e-04265424C0024121
DiseaseMalignant neoplasm of lung

MET ERBB2 ERBB3 JAG1

5.52e-04266424C0242379
Diseasemigraine disorder, diastolic blood pressure

KIAA0040 ITGB5

5.81e-0425422EFO_0006336, MONDO_0005277
DiseaseLymphatic Metastasis

MET ERBB2

6.29e-0426422C0024232
Diseasecerebral white matter volume change measurement, age at assessment

PRICKLE2 TNFRSF21

7.30e-0428422EFO_0008007, EFO_0021499
Diseaseintraocular pressure measurement

LTBP1 LTBP2 ZNRF3 NALF2 TSPAN10

7.53e-04509425EFO_0004695
DiseaseMalignant Neoplasms

MET ERBB2 ERBB3

8.09e-04128423C0006826
Diseaseintestinal cancer (implicated_via_orthology)

ERBB2 ERBB3

9.55e-0432422DOID:10155 (implicated_via_orthology)
DiseaseHead and Neck Neoplasms

ERBB2 ERBB3

1.02e-0333422C0018671
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

MYF6 MYOG

1.21e-0336422DOID:11723 (implicated_via_orthology)
Diseaseductal carcinoma in situ (is_marker_for)

ERBB2 ERBB3

1.42e-0339422DOID:0060074 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
ACHPCSPMCKGSRCW

ERBB2

191

P04626
RSCPPCHEVCKGRCW

ERBB3

181

P21860
NDCWCHCGPKFPECN

BRINP3

276

Q76B58
PWLQPCCGHFPFCSC

ARSD

571

P51689
SVQPGEVCCWLCIPC

GRM2

511

Q14416
KTVKGMPCCWHCEPC

GRM4

531

Q14833
HLCGCWKQCPSCGAI

GVINP1

2281

Q7Z2Y8
WGCCPIPEAVCCSDH

GRN

386

P28799
GGSWACCQLPHAVCC

GRN

461

P28799
WHYQPCGAPCLKTCR

MUC5B

1166

Q9HC84
CTCSHCLEQPGCGWC

ATRN

991

O75882
ITLLFICCHCCWSPP

KIAA0040

41

Q15053
ICCHCCWSPPGKRGQ

KIAA0040

46

Q15053
CLPLCHCKPCMHVWS

FER1L4

516

A9Z1Z3
LCCCSVGKAWGPHCE

LTBP1

701

Q14766
PHCPGQCLIWACKTC

MYF6

71

P23409
TPRCKWCTNCPEGAC

MEGF8

1951

Q7Z7M0
CCCCWAPRPSDKPCA

NALF2

21

O75949
WVCPPCRGICNCSYC

CDCA7L

401

Q96GN5
CEECLLIHPKCAWCS

ITGB5

36

P18084
NCKTYWKSCCPCCPP

MT4

26

P47944
FQHWAGLPCPCTICQ

OLIG3

231

Q7RTU3
HGVCWHPPCFVCTVC

PRICKLE2

151

Q7Z3G6
HIYPWCKCCQPCVVN

P2RX7

366

Q99572
CLCGTAWLCCSPNRK

CSF3R

641

Q99062
CWCPANSTGKFCHLP

LTBP2

416

Q14767
CWCPLLQGIACLCCD

GBF1

1541

Q92538
HPGLGSNCCVPCFCW

GOLGA8B

581

A8MQT2
GEWFCPPCQHKLLCE

RSF1

931

Q96T23
CVHGICNEPWQCLCE

JAG1

271

P78504
ACSKVWCGPRPCLLH

JAG1

891

P78504
SAPPFVQCGWCHDKC

MET

531

P08581
PAAPSRNPCCLCWCC

RGS19

31

P49795
WILPHGTCPICKCDI

RNF133

286

Q8WVZ7
CDDLVHCVWRCQPGC

SSPOP

3331

A2VEC9
ATSCPCLCWHLQPGA

SSPOP

4831

A2VEC9
NGIEKCHDCSQPCPW

TNFRSF21

101

O75509
PNWHCPPCRGICNCS

CDCA7

316

Q9BWT1
WLACCCCLSLPGQLP

C11orf21

86

Q9P2W6
LNQSCLCLAWSPPCC

WDR90

1476

Q96KV7
FHLCCCCSWPQGAVP

TREML4

11

Q6UXN2
FVLVGICWCQCCPHS

ILDR2

201

Q71H61
QFWGPDCKELCSCHP

SCARF2

116

Q96GP6
LCSPCVEPCVWRCQH

ZNFX1

1506

Q9P2E3
EAWGCSCCPPETKHQ

TSPAN10

41

Q9H1Z9
WKGGHELPSCACCCE

ZNRF3

701

Q9ULT6
QCPHHCPVLGCWSGC

PRO3102

61

Q9H379
CPGQCLPWACKVCKR

MYOG

61

P15173