Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion binding

NR2C2 MID2 RNF19A FBXO11 GRIN2A UPF1 ZSWIM6 PTCH1 TRIM27 PIAS1 TRIM22 FBXO30 PIAS4 HHIP ERAP2 MID1 UHRF1 KMT2A PRKN KPNB1

3.91e-0789112120GO:0008270
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

MKRN4P RNF19A MKRN1 TRIM27 PIAS1 TRIM22 FBXO30 RNF170 PIAS4 UHRF1 PRKN RNF138

5.52e-0639812112GO:0061659
GeneOntologyMolecularFunctiontransition metal ion binding

CYP1A1 NR2C2 MID2 RNF19A FBXO11 GRIN2A UPF1 ZSWIM6 PTCH1 TRIM27 PIAS1 TRIM22 FBXO30 PIAS4 HHIP ERAP2 MID1 UHRF1 KMT2A PRKN KPNB1

8.78e-06118912121GO:0046914
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

MKRN4P RNF19A MKRN1 FBXO11 TRIM27 PIAS1 TRIM22 FBXO30 RNF170 PIAS4 UHRF1 PRKN RNF138

1.40e-0551212113GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

MKRN4P RNF19A MKRN1 FBXO11 TRIM27 PIAS1 TRIM22 FBXO30 RNF170 PIAS4 UHRF1 PRKN RNF138

2.09e-0553212113GO:0016755
GeneOntologyMolecularFunctionubiquitin protein ligase activity

MKRN4P RNF19A MKRN1 TRIM27 TRIM22 FBXO30 RNF170 UHRF1 PRKN RNF138

9.03e-0537212110GO:0061630
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

MKRN4P RNF19A MKRN1 FBXO11 TRIM27 TRIM22 FBXO30 RNF170 UHRF1 PRKN RNF138

1.44e-0447312111GO:0004842
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A3 COL4A5 COL4A6 COL14A1

1.72e-04461214GO:0030020
GeneOntologyMolecularFunctionhedgehog family protein binding

PTCH1 HHIP

2.17e-0441212GO:0097108
GeneOntologyMolecularFunctionacyltransferase activity

MKRN4P GLYATL3 RNF19A MKRN1 FBXO11 TRIM27 PIAS1 TRIM22 FBXO30 RNF170 PIAS4 UHRF1 PRKN RNF138

2.54e-0477512114GO:0016746
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A3 COL4A5 COL4A6 COL14A1 PRG4 FBN3

1.01e-031881216GO:0005201
GeneOntologyMolecularFunctionSUMO transferase activity

TRIM27 PIAS1 PIAS4

1.34e-03361213GO:0019789
GeneOntologyBiologicalProcesspost-translational protein modification

MKRN4P MID2 RNF19A PARP8 MKRN1 FBXO11 KBTBD2 TRIM27 PIAS1 TRIM22 FBXO30 RNF170 PIAS4 USP31 KLHL7 UHRF1 PRKN RNF138 HSP90AA1

1.56e-05107412119GO:0043687
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

MKRN4P MID2 RNF19A MKRN1 FBXO11 KBTBD2 TRIM27 PIAS1 TRIM22 FBXO30 RNF170 PIAS4 KLHL7 UHRF1 PRKN RNF138 HSP90AA1

1.82e-0589312117GO:0032446
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

MKRN4P MID2 RNF19A MKRN1 FBXO11 KBTBD2 TRIM27 PIAS1 TRIM22 FBXO30 RNF170 PIAS4 USP31 KLHL7 UHRF1 PRKN RNF138 HSP90AA1

2.40e-05100912118GO:0070647
GeneOntologyBiologicalProcessregulation of catabolic process

TSPAN15 TMEM67 MID2 RNF19A TMEM59 FBXO11 GRIN2A UPF1 TRIM27 PIAS1 TRIM22 PIAS4 PPP2CA LZTS1 PLIN5 HNRNPA0 PRKN EXOC1 HSP90AA1 TRDMT1

3.92e-05125212120GO:0009894
GeneOntologyBiologicalProcesscollagen-activated tyrosine kinase receptor signaling pathway

COL4A3 COL4A5 COL4A6

4.17e-05121213GO:0038063
GeneOntologyBiologicalProcessprotein ubiquitination

MKRN4P MID2 RNF19A MKRN1 FBXO11 KBTBD2 TRIM27 TRIM22 FBXO30 RNF170 KLHL7 UHRF1 PRKN RNF138 HSP90AA1

8.14e-0581112115GO:0016567
GeneOntologyCellularComponentcollagen type IV trimer

COL4A3 COL4A5 COL4A6

3.74e-0661213GO:0005587
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A3 COL4A5 COL4A6

1.04e-0581213GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A3 COL4A5 COL4A6

1.04e-0581213GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A3 COL4A5 COL4A6

1.04e-0581213GO:0098645
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A3 COL4A5 COL4A6

2.33e-04211213GO:0098644
GeneOntologyCellularComponentbasement membrane

COL4A3 COL4A5 COL4A6 VWC2 LAMC3

7.23e-041221215GO:0005604
GeneOntologyCellularComponentendoplasmic reticulum tubular network

ZFYVE27 PARP8 KPNB1

7.55e-04311213GO:0071782
HumanPhenoLenticonus

COL4A3 COL4A5 COL4A6

6.92e-0510443HP:0001142
HumanPhenoTracheobronchial leiomyomatosis

COL4A5 COL4A6

7.29e-052442HP:0006524
HumanPhenoDyspepsia

COL4A5 COL4A6

7.29e-052442HP:0410281
HumanPhenoDiffuse leiomyomatosis

COL4A5 COL4A6

7.29e-052442HP:0006756
HumanPhenoEsophageal neoplasm

COL4A5 COL4A6 LZTS1 COL14A1

9.83e-0529444HP:0100751
DomainZF_RING_1

MKRN4P MID2 RNF19A MKRN1 TRIM27 TRIM22 RNF170 MID1 UHRF1 PRKN RNF138

2.18e-0629111711PS00518
DomainZF_RING_2

MKRN4P MID2 RNF19A MKRN1 TRIM27 TRIM22 RNF170 MID1 UHRF1 PRKN RNF138

2.75e-0629811711PS50089
DomainC4

COL4A3 COL4A5 COL4A6

4.73e-0661173SM00111
DomainCollagen_VI_NC

COL4A3 COL4A5 COL4A6

4.73e-0661173IPR001442
DomainNC1_IV

COL4A3 COL4A5 COL4A6

4.73e-0661173PS51403
Domain-

COL4A3 COL4A5 COL4A6

4.73e-06611732.170.240.10
DomainC4

COL4A3 COL4A5 COL4A6

4.73e-0661173PF01413
Domainzf-MIZ

PIAS1 PIAS4 RNF138

8.23e-0671173PF02891
DomainZnf_MIZ

PIAS1 PIAS4 RNF138

1.31e-0581173IPR004181
DomainRING

MKRN4P MID2 RNF19A MKRN1 TRIM27 TRIM22 RNF170 MID1 UHRF1 RNF138

2.22e-0530511710SM00184
Domain-

ZFYVE27 MID2 RNF19A MKRN1 TRIM27 TRIM22 RNF170 PIAS4 MID1 UHRF1 KMT2A RNF138

2.52e-05449117123.30.40.10
DomainZnf_RING/FYVE/PHD

ZFYVE27 MID2 RNF19A MKRN1 TRIM27 TRIM22 RNF170 PIAS4 MID1 UHRF1 KMT2A RNF138

3.13e-0545911712IPR013083
DomainZnf_RING

MKRN4P MID2 RNF19A MKRN1 TRIM27 TRIM22 RNF170 MID1 UHRF1 RNF138

3.92e-0532611710IPR001841
DomainZnf_RING_CS

MID2 MKRN1 TRIM27 TRIM22 RNF170 MID1 UHRF1

7.52e-051631177IPR017907
Domainzf-C3HC4

MKRN4P MID2 MKRN1 TRIM27 TRIM22 RNF170 MID1 RNF138

8.14e-052231178PF00097
DomainPINIT

PIAS1 PIAS4

2.32e-0441172PS51466
DomainPINIT

PIAS1 PIAS4

2.32e-0441172PF14324
DomainPINIT

PIAS1 PIAS4

2.32e-0441172IPR023321
DomainZF_SP_RING

PIAS1 PIAS4

8.00e-0471172PS51044
DomainBBOX

MID2 TRIM27 TRIM22 MID1

9.24e-04691174SM00336
DomainButyrophylin

MID2 TRIM27 TRIM22 MID1

9.75e-04701174IPR003879
Domain-

MID2 TRIM27 TRIM22 MID1

1.03e-037111744.10.45.10
DomainCyclin_L/T

CCNL2 CCNL1

1.06e-0381172IPR015429
DomainPH-BEACH_dom

WDFY4 LYST

1.06e-0381172IPR023362
Domain-

WDFY4 LYST

1.06e-03811722.30.29.40
DomainPH_BEACH

WDFY4 LYST

1.06e-0381172PS51783
Domainzf-B_box

MID2 TRIM27 TRIM22 MID1

1.08e-03721174PF00643
Domainzf-RING_UBOX

MID2 TRIM22 MID1

1.24e-03341173PF13445
DomainZnf-RING_LisH

MID2 TRIM22 MID1

1.24e-03341173IPR027370
DomainARM-type_fold

NCAPD3 WAPL VEPH1 ARID1A WDFY4 LYST SF3B1 KPNB1

1.33e-033391178IPR016024
DomainBEACH

WDFY4 LYST

1.36e-0391172PS50197
DomainBeach

WDFY4 LYST

1.36e-0391172PF02138
Domain-

WDFY4 LYST

1.36e-03911721.10.1540.10
DomainBeach

WDFY4 LYST

1.36e-0391172SM01026
DomainBEACH_dom

WDFY4 LYST

1.36e-0391172IPR000409
DomainZF_BBOX

MID2 TRIM27 TRIM22 MID1

1.60e-03801174PS50119
DomainZnf_B-box

MID2 TRIM27 TRIM22 MID1

1.68e-03811174IPR000315
DomainE3_UB_ligase_RBR

RNF19A PRKN

1.69e-03101172IPR031127
DomainCollagen

COL4A3 COL4A5 COL4A6 COL14A1

2.00e-03851174IPR008160
DomainCollagen

COL4A3 COL4A5 COL4A6 COL14A1

2.00e-03851174PF01391
DomainSPRY

MID2 TRIM27 TRIM22 MID1

2.18e-03871174SM00449
DomainCOS

MID2 MID1

2.46e-03121172PS51262
DomainCOS_domain

MID2 MID1

2.46e-03121172IPR017903
DomainConA-like_dom

MID2 TRIM27 TRIM22 MID1 SEL1L3 COL14A1

2.58e-032191176IPR013320
DomainSPRY

MID2 TRIM27 TRIM22 MID1

2.89e-03941174PF00622
DomainSPRY_dom

MID2 TRIM27 TRIM22 MID1

2.89e-03941174IPR003877
DomainPP2Ac

PPP2CA PPP2CB

2.90e-03131172SM00156
DomainSer/Thr-sp_prot-phosphatase

PPP2CA PPP2CB

2.90e-03131172IPR006186
DomainSER_THR_PHOSPHATASE

PPP2CA PPP2CB

2.90e-03131172PS00125
DomainB30.2/SPRY

MID2 TRIM27 TRIM22 MID1

3.00e-03951174IPR001870
DomainB302_SPRY

MID2 TRIM27 TRIM22 MID1

3.00e-03951174PS50188
DomainIBR

RNF19A PRKN

3.37e-03141172PF01485
DomainIBR

RNF19A PRKN

3.37e-03141172SM00647
DomainHEAT

NCAPD3 SF3B1 KPNB1

3.38e-03481173PF02985
DomainBbox_C

MID2 MID1

3.87e-03151172IPR003649
DomainBBC

MID2 MID1

3.87e-03151172SM00502
DomainIBR_dom

RNF19A PRKN

3.87e-03151172IPR002867
DomainIRK

KCNJ4 KCNJ14

4.41e-03161172PF01007
DomainK_chnl_inward-rec_Kir_cyto

KCNJ4 KCNJ14

4.41e-03161172IPR013518
Domain-

KCNJ4 KCNJ14

4.41e-031611722.60.40.1400
DomainK_chnl_inward-rec_Kir

KCNJ4 KCNJ14

4.41e-03161172IPR016449
DomainZnf_C3HC4_RING-type

MID2 MKRN1 TRIM27 TRIM22 RNF170

4.57e-031721175IPR018957
DomainCTDL_fold

COL4A3 COL4A5 COL4A6 CLEC2L

4.60e-031071174IPR016187
DomainMFS

SLC22A23 SLC16A12 SLCO5A1 SV2C

4.75e-031081174PS50850
DomainCyclin_C-dom

CCNL2 CCNL1

4.98e-03171172IPR004367
DomainCyclin_C

CCNL2 CCNL1

4.98e-03171172PF02984
DomainCyclin_C

CCNL2 CCNL1

4.98e-03171172SM01332
DomainHEAT

NCAPD3 SF3B1 KPNB1

5.75e-03581173IPR000357
DomainGuanylate_cyc

ADCY1 GUCY1B2

6.21e-03191172PF00211
DomainGUANYLATE_CYCLASE_2

ADCY1 GUCY1B2

6.21e-03191172PS50125
DomainA/G_cyclase

ADCY1 GUCY1B2

6.21e-03191172IPR001054
DomainGUANYLATE_CYCLASE_1

ADCY1 GUCY1B2

6.21e-03191172PS00452
DomainCYCc

ADCY1 GUCY1B2

6.21e-03191172SM00044
PathwayBIOCARTA_NPP1_PATHWAY

COL4A3 COL4A5 COL4A6

2.46e-0510853M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A3 COL4A5 COL4A6

2.46e-0510853MM1560
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A3 COL4A5 COL4A6 LAMC3

2.99e-0530854M27216
PathwayBIOCARTA_VITCB_PATHWAY

COL4A3 COL4A5 COL4A6

3.37e-0511853M15422
PathwayBIOCARTA_VITCB_PATHWAY

COL4A3 COL4A5 COL4A6

4.48e-0512853MM1526
PathwayBIOCARTA_ACE2_PATHWAY

COL4A3 COL4A5 COL4A6

5.79e-0513853MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A3 COL4A5 COL4A6

5.79e-0513853M12950
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A3 COL4A5 COL4A6

7.34e-0514853MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A3 COL4A5 COL4A6

7.34e-0514853M6487
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL4A3 COL4A5 COL4A6 COL14A1 HSP90AA1

8.22e-0574855M160
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A3 COL4A5 COL4A6

9.14e-0515853M27161
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A3 COL4A5 COL4A6

9.14e-0515853MM14922
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A3 COL4A5 COL4A6 COL14A1

1.05e-0441854MM15538
PathwayPID_INTEGRIN3_PATHWAY

COL4A3 COL4A5 COL4A6 CD47

1.27e-0443854M53
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A3 COL4A5 COL4A6 COL14A1

1.39e-0444854M27812
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A3 COL4A5 COL4A6

1.62e-0418853M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A3 COL4A5 COL4A6

1.62e-0418853MM14882
PathwayPID_SYNDECAN_1_PATHWAY

COL4A3 COL4A5 COL4A6 COL14A1

1.66e-0446854M198
PathwayBIOCARTA_AMI_PATHWAY

COL4A3 COL4A5 COL4A6

2.24e-0420853M15394
PathwayKEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING

NCAPD3 PPP2CA PPP2CB

2.24e-0420853M47876
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A3 COL4A5 COL4A6 COL14A1

2.29e-0450854MM14796
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A3 COL4A5 COL4A6

3.43e-0423853M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A3 COL4A5 COL4A6

3.43e-0423853MM1427
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A3 COL4A5 COL4A6 LAMC3

4.35e-0459854M27218
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A3 COL4A5 COL4A6 COL14A1

4.95e-0461854M27103
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A3 COL4A5 COL4A6 COL14A1

4.95e-0461854MM14637
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A3 COL4A5 COL4A6 COL14A1

5.94e-0464854M26953
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A3 COL4A5 COL4A6 COL14A1

7.07e-0467854M26999
PathwayREACTOME_GLI_PROTEINS_BIND_PROMOTERS_OF_HH_RESPONSIVE_GENES_TO_PROMOTE_TRANSCRIPTION

PTCH1 HHIP

7.40e-047852M27501
PathwayREACTOME_PP2A_MEDIATED_DEPHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS

PPP2CA PPP2CB

7.40e-047852M26992
PathwayREACTOME_LIGAND_RECEPTOR_INTERACTIONS

PTCH1 HHIP

7.40e-047852MM15224
PathwayREACTOME_BACTERIAL_INFECTION_PATHWAYS

TRIM27 SV2C HSP90AA1 KPNB1

8.80e-0471854M48033
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A3 COL4A5 COL4A6

9.25e-0432853MM14924
PathwayREACTOME_LIGAND_RECEPTOR_INTERACTIONS

PTCH1 HHIP

9.83e-048852M27496
PathwayWP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME

WAPL PPP2CA PPP2CB

1.11e-0334853M42555
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A3 COL4A5 COL4A6 CD47

1.14e-0376854MM14867
PathwayREACTOME_COLLAGEN_FORMATION

COL4A3 COL4A5 COL4A6 COL14A1

1.14e-0376854MM14573
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A3 COL4A5 COL4A6 COL14A1 FBN3

1.56e-03140855M587
PathwayBIOCARTA_CHREBP_PATHWAY

ADCY1 PPP2CA

1.57e-0310852MM1530
PathwayREACTOME_MASTL_FACILITATES_MITOTIC_PROGRESSION

PPP2CA PPP2CB

1.57e-0310852M27176
PathwayREACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1

PPP2CA PPP2CB

1.57e-0310852MM14509
PathwayKEGG_SMALL_CELL_LUNG_CANCER

COL4A6 LAMC3 PIAS1 PIAS4

1.65e-0384854M3228
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL4A6 LAMC3 CD47 SV2C

1.65e-0384854M7098
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

TRIM27 PIAS1 PIAS4

1.65e-0339853M27238
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A3 COL4A5 COL4A6 CD47

1.72e-0385854M16441
Pubmed

COL4A6 is dispensable for autosomal recessive Alport syndrome.

COL4A3 COL4A5 COL4A6

4.32e-083123327377778
Pubmed

The E3 ubiquitin ligase- and protein phosphatase 2A (PP2A)-binding domains of the Alpha4 protein are both required for Alpha4 to inhibit PP2A degradation.

PPP2CA PPP2CB MID1

1.72e-074123321454489
Pubmed

Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4.

PPP2CA PPP2CB MID1

1.72e-074123311371618
Pubmed

The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic.

PACS1 PPP2CA PPP2CB

1.72e-074123314633983
Pubmed

PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.

TRIM27 PIAS1 PIAS4

4.29e-075123315907835
Pubmed

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.

COL4A3 COL4A5 COL4A6 PTCH1

5.54e-0719123415689378
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GABRB3 YTHDC2 GRIN2A UPF1 ARID1A ALG2 USP31 PACS1 PPP2CB SF3B1 LZTS1 HNRNPA0 KMT2A EXOC1 PCBP1 SNRNP200 CACNA2D3 HSP90AA1 KPNB1

6.91e-0714311231937142655
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A3 COL4A5 COL4A6

8.57e-07612332426947
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A3 COL4A5 COL4A6

8.57e-076123310534397
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A3 COL4A5 COL4A6

8.57e-076123319275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A3 COL4A5 COL4A6

8.57e-07612336988303
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A3 COL4A5 COL4A6

8.57e-07612339506531
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A3 COL4A5 COL4A6

8.57e-076123323551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A3 COL4A5 COL4A6

8.57e-07612336811420
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A3 COL4A5 COL4A6

8.57e-07612336389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A3 COL4A5 COL4A6

8.57e-076123312225806
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A3 COL4A5 COL4A6

8.57e-07612339673377
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A3 COL4A5 COL4A6

8.57e-076123311732842
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

WAPL YTHDC2 UPF1 ARID1A SF3B1 CPNE3 HNRNPA0 EXOC1 PCBP1 SNRNP200 HSP90AA1 KPNB1

1.15e-065821231220467437
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

ARID1A PIAS1 SF3B1 CPNE3 HNRNPA0 PCBP1 SNRNP200 HSP90AA1

1.25e-06220123835785414
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A3 COL4A5 COL4A6

1.50e-06712338006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A3 COL4A5 COL4A6

1.50e-067123310416788
Pubmed

X-linked microtubule-associated protein, Mid1, regulates axon development.

PPP2CA PPP2CB MID1

1.50e-067123324194544
Pubmed

Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals.

COL4A3 COL4A5 COL4A6

1.50e-067123317418794
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A3 COL4A5 COL4A6

1.50e-067123311711546
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A3 COL4A5 COL4A6

1.50e-06712331724753
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

COL4A3 COL4A5 COL4A6 LAMC3

2.10e-0626123424742657
Pubmed

Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.

COL4A3 COL4A5 COL4A6

2.39e-06812331377218
Pubmed

Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.

COL4A3 COL4A5 COL4A6

2.39e-068123310970885
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL4A3 COL4A5 COL4A6

2.39e-06812333997552
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A3 COL4A5 COL4A6

2.39e-068123329422532
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL4A3 COL4A5 COL4A6

2.39e-068123310382266
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

DIP2B NCAPD3 WAPL UPF1 PIAS4 SF3B1 HNRNPA0 SNRNP200 HSP90AA1

3.00e-06332123932786267
Pubmed

Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital.

PPP2CA PPP2CB HSP90AA1

3.57e-069123312885400
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A3 COL4A5 COL4A6

3.57e-069123312101409
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A3 COL4A5 COL4A6

3.57e-06912339878537
Pubmed

Dissection of behavior and psychiatric disorders using the mouse as a model.

GABRB3 GRIN2A ADCY1 CD47

4.35e-0631123410767319
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A3 COL4A5 COL4A6

5.09e-061012339136074
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A3 COL4A5 COL4A6

6.98e-061112337500359
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A3 COL4A5 COL4A6

6.98e-0611123314998921
Pubmed

HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells.

CXCL10 TRIM22 CCL8 KPNB1

8.99e-0637123424742347
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A3 COL4A5 COL4A6

9.28e-0612123315837576
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A3 COL4A5 COL4A6

9.28e-0612123316024816
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A3 COL4A5 COL4A6

9.28e-0612123312180907
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

COL4A3 COL4A5 COL4A6 VWC2 LAMC3

9.32e-0679123518757743
Pubmed

Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.

MID2 FBXO11 TRIM27 PPP2CA MID1

9.32e-0679123529121065
Pubmed

Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A.

PPP2CA PPP2CB

1.24e-05212322555176
Pubmed

Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis.

PPP2CA PPP2CB

1.24e-052123211751260
Pubmed

Deletion of the paired alpha 5(IV) and alpha 6(IV) collagen genes in inherited smooth muscle tumors.

COL4A5 COL4A6

1.24e-05212328356449
Pubmed

Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation.

MKRN4P MKRN1

1.24e-052123230143610
Pubmed

The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain.

EI24 KPNB1

1.24e-052123224821838
Pubmed

Mutation detection of COL4An gene based on mRNA of peripheral blood lymphocytes and prenatal diagnosis of Alport syndrome in China.

COL4A3 COL4A5

1.24e-052123221143337
Pubmed

Evaluating the potential of IP-10 and MCP-2 as biomarkers for the diagnosis of tuberculosis.

CXCL10 CCL8

1.24e-052123218684849
Pubmed

TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release.

CXCL10 CCL8

1.24e-052123215644410
Pubmed

Differential expression of mouse alpha5(IV) and alpha6(IV) collagen genes in epithelial basement membranes.

COL4A5 COL4A6

1.24e-052123210965041
Pubmed

Immunohistochemical localization of type IV collagen alpha chains in the basement membrane of the pancreatic duct in human normal pancreas and pancreatic diseases.

COL4A5 COL4A6

1.24e-052123215211113
Pubmed

Clonal overgrowth of esophageal smooth muscle cells in diffuse leiomyomatosis-Alport syndrome caused by partial deletion in COL4A5 and COL4A6 genes.

COL4A5 COL4A6

1.24e-052123220951201
Pubmed

MID1-PP2A complex functions as new insights in human lung adenocarcinoma.

PPP2CA MID1

1.24e-052123229450633
Pubmed

Regional expression of protein phosphatase type 1 and 2A catalytic subunit isoforms in the human heart.

PPP2CA PPP2CB

1.24e-052123211113010
Pubmed

Origin and evolution of processed pseudogenes that stabilize functional Makorin1 mRNAs in mice, primates and other mammals.

MKRN4P MKRN1

1.24e-052123216415359
Pubmed

Differential promoter usages of PTCH1 and down regulation of HHIP are associated with HNSCC progression.

PTCH1 HHIP

1.24e-052123235276608
Pubmed

Bifunctional promoter of type IV collagen COL4A5 and COL4A6 genes regulates the expression of alpha5 and alpha6 chains in a distinct cell-specific fashion.

COL4A5 COL4A6

1.24e-052123215598179
Pubmed

Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome.

MID2 MID1

1.24e-052123226788540
Pubmed

The role of protein phosphatase 2A catalytic subunit Calpha in embryogenesis: evidence from sequence analysis and localization studies.

PPP2CA PPP2CB

1.24e-052123210543450
Pubmed

An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene.

MKRN4P MKRN1

1.24e-052123212721631
Pubmed

Genotype-phenotype correlations for COL4A3-COL4A5 variants resulting in Gly substitutions in Alport syndrome.

COL4A3 COL4A5

1.24e-052123235177655
Pubmed

Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities.

PPP2CA PPP2CB

1.24e-052123234902541
Pubmed

Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes.

PPP2CA PPP2CB

1.24e-05212322837763
Pubmed

Role for O-glycosylation of RFP in the interaction with enhancer of polycomb.

TRIM27 EPC1

1.24e-052123211779184
Pubmed

Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes.

PPP2CA PPP2CB

1.24e-05212321846293
Pubmed

Alport syndrome and leiomyomatosis: the first deletion extending beyond COL4A6 intron 2.

COL4A5 COL4A6

1.24e-052123221380622
Pubmed

Prevalence Estimates of Predicted Pathogenic COL4A3-COL4A5 Variants in a Population Sequencing Database and Their Implications for Alport Syndrome.

COL4A3 COL4A5

1.24e-052123234400539
Pubmed

Possible Digenic Disease in a Caucasian Family with COL4A3 and COL4A5 Mutations.

COL4A3 COL4A5

1.24e-052123230661074
Pubmed

Tissue- and developmental stage-specific activation of alpha 5 and alpha 6(IV) collagen expression in the upper gastrointestinal tract of transgenic mice.

COL4A5 COL4A6

1.24e-052123214592452
Pubmed

PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte.

PPP2CA PPP2CB

1.24e-052123227096707
Pubmed

Identification of Makorin 1 as a novel SEREX antigen of esophageal squamous cell carcinoma.

MKRN4P MKRN1

1.24e-052123219604354
Pubmed

Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism.

COL4A5 COL4A6

1.24e-052123226179878
Pubmed

The putatively functional Mkrn1-p1 pseudogene is neither expressed nor imprinted, nor does it regulate its source gene in trans.

MKRN4P MKRN1

1.24e-052123216882727
Pubmed

Spectrum of clinical features and type IV collagen alpha-chain distribution in Chinese patients with Alport syndrome.

COL4A3 COL4A5

1.24e-052123216940319
Pubmed

Guidelines for Genetic Testing and Management of Alport Syndrome.

COL4A3 COL4A5

1.24e-052123234930753
Pubmed

Altered expression of PTCH and HHIP in gastric cancer through their gene promoter methylation: novel targets for gastric cancer.

PTCH1 HHIP

1.24e-052123223440386
Pubmed

Characterization of contiguous gene deletions in COL4A6 and COL4A5 in Alport syndrome-diffuse leiomyomatosis.

COL4A5 COL4A6

1.24e-052123228275241
Pubmed

Discordance between skin biopsy and kidney biopsy in an X-linked carrier of Alport syndrome.

COL4A3 COL4A5

1.24e-052123217294221
Pubmed

Loss of expression of type IV collagen alpha5 and alpha6 chains in colorectal cancer associated with the hypermethylation of their promoter region.

COL4A5 COL4A6

1.24e-052123216507901
Pubmed

The tripartite motif family identifies cell compartments.

MID2 TRIM27 TRIM22 MID1

1.36e-0541123411331580
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A3 COL4A5 COL4A6

1.53e-0514123312878203
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

ARID1A PIAS1 SF3B1 HNRNPA0 UHRF1 KMT2A PCBP1 SNRNP200 HSP90AA1

1.65e-05411123935182466
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

HIPK1 YTHDC2 TRIM22 RGS3 FBXO30 SF3B1 EXOC1

2.03e-05233123737704626
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DIP2B NCAPD3 WAPL YTHDC2 PASK PACS1 SF3B1 CCNL1 KMT2A PCBP1 PRG4 SNRNP200

2.05e-057741231215302935
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DIP2B NCAPD3 WAPL EI24 YTHDC2 PIAS1 RGS3 PACS1 MID1 CPNE3 KMT2A

2.08e-056501231138777146
Pubmed

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

UPF1 PPP2CA PPP2CB SF3B1 HNRNPA0 PCBP1 SNRNP200 HSP90AA1 KPNB1

2.15e-05425123921081503
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

RNF19A TRIM27 PIAS1 RNF170 PRKN

2.29e-0595123529643511
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A3 COL4A5 COL4A6

2.34e-0516123315878328
Pubmed

The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.

UPF1 SF3B1 HNRNPA0 PCBP1 SNRNP200 HSP90AA1 KPNB1

2.39e-05239123726641092
Pubmed

Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.

UPF1 SF3B1 CPNE3 HNRNPA0 PCBP1 SNRNP200 KPNB1

2.52e-05241123723125841
Pubmed

TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.

MID2 TRIM27 TRIM22

3.39e-0518123323077300
Pubmed

Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.

PPP2CA PPP2CB HSP90AA1

3.39e-0518123323287597
Pubmed

An integrated workflow for charting the human interaction proteome: insights into the PP2A system.

GLYATL3 PPP2CA PPP2CB CCT6B KPNB1

3.71e-05105123519156129
Pubmed

Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome.

COL4A3 COL4A5

3.71e-053123227576055
Pubmed

The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.

PTCH1 HHIP

3.71e-053123219561609
InteractionPPP4C interactions

GLYATL3 MID2 PPP2CA PPP2CB SF3B1 MID1 CCT6B PRKN

1.78e-061421178int:PPP4C
InteractionCCL26 interactions

WAPL CXCL10 VWDE PASK CCL8

2.27e-06371175int:CCL26
InteractionTRIM32 interactions

MID2 TMEM59 TRIM27 PIAS1 PIAS4 PRKN EXOC1 HSP90AA1

1.71e-051931178int:TRIM32
InteractionWRAP53 interactions

NR2C2 WAPL CCT6B UHRF1 PRKN PCBP1

1.81e-05941176int:WRAP53
InteractionETF1 interactions

CYP1A1 NR2C2 UPF1 ARID1A PPP2CA PRKN KPNB1

1.93e-051421177int:ETF1
InteractionPKN1 interactions

MID2 TRIM27 MID1 KMT2A PRKN PCBP1 HSP90AA1

2.21e-051451177int:PKN1
InteractionPPP2CA interactions

GABRB3 NR2C2 NCAPD3 GRIN2A PACS1 PPP2CA PPP2CB MID1 INTS15 EPC1 PRKN KPNB1

2.51e-0548411712int:PPP2CA
InteractionGATA4 interactions

UPF1 ARID1A PIAS1 SF3B1 HNRNPA0 UHRF1 KMT2A PRKN PCBP1 SNRNP200 HSP90AA1

2.78e-0541111711int:GATA4
InteractionERG interactions

HIPK1 ARID1A PIAS1 ZBTB44 SF3B1 UHRF1 PCBP1 SNRNP200

4.81e-052231178int:ERG
InteractionCHUK interactions

NR2C2 TRIM27 PIAS1 TRIM22 PPP2CA PPP2CB PRKN HSP90AA1

4.96e-052241178int:CHUK
InteractionFAM50B interactions

CCNL2 MID2 LZTS1 MID1 CCNL1

5.06e-05691175int:FAM50B
InteractionAXIN1 interactions

MID2 MKRN1 TRIM27 PIAS1 PIAS4 PPP2CA PPP2CB

5.26e-051661177int:AXIN1
InteractionUBE2L6 interactions

RNF19A TRIM27 MID1 PRKN PCBP1 KPNB1

5.94e-051161176int:UBE2L6
InteractionUBE2D4 interactions

MID2 MKRN1 TRIM27 MID1 PRKN RNF138

6.85e-051191176int:UBE2D4
InteractionMAP7 interactions

FBXO11 YTHDC2 UPF1 TRIM27 PIAS1 MMADHC PASK PPP2CB

7.81e-052391178int:MAP7
InteractionSKIC8 interactions

NR2C2 PPP2CA PPP2CB SF3B1 CCT6B KMT2A PRKN SNRNP200

7.81e-052391178int:SKIC8
InteractionBRCA2 interactions

UPF1 ARID1A PIAS1 AARSD1 PIAS4 PPP2CA CT55 KMT2A PRG4 HSP90AA1

8.20e-0538411710int:BRCA2
InteractionCDK11A interactions

CCNL2 CCNL1 CCT6B PRKN HSP90AA1 KPNB1 HSP90AB3P

8.76e-051801177int:CDK11A
InteractionSMAD1 interactions

VEPH1 ARID1A PIAS1 FBXO30 PIAS4 ZBTB44 SF3B1 CPNE3

8.77e-052431178int:SMAD1
InteractionBRCA1 interactions

CCNL2 NCAPD3 WAPL MID2 UPF1 ARID1A TRIM27 PIAS1 PIAS4 PPP2CA SF3B1 HNRNPA0 SLX4IP UHRF1 PRKN PCBP1 SNRNP200 HSP90AA1 KPNB1

1.02e-04124911719int:BRCA1
InteractionSNW1 interactions

NR2C2 WAPL YTHDC2 UPF1 ARID1A SF3B1 CPNE3 HNRNPA0 KMT2A EXOC1 PCBP1 SNRNP200 HSP90AA1 KPNB1

1.10e-0474711714int:SNW1
InteractionDCN interactions

COL4A3 COL4A5 COL4A6 COL14A1

1.12e-04431174int:DCN
InteractionCRY2 interactions

VWC2 PPP2CB MID1 PCBP1 SNRNP200 HSP90AA1 HSP90AB3P

1.40e-041941177int:CRY2
InteractionHABP2 interactions

COL4A3 COL4A5 COL4A6

1.46e-04181173int:HABP2
GeneFamilyRing finger proteins

MKRN4P MID2 RNF19A MKRN1 TRIM27 TRIM22 RNF170 MID1 UHRF1 RNF138

4.09e-07275811058
GeneFamilyCollagens

COL4A3 COL4A5 COL4A6 COL14A1

5.29e-0546814490
GeneFamilyZinc fingers MIZ-type

PIAS1 PIAS4

4.10e-04781285
GeneFamilyWD repeat domain containing|BEACH domain containing

WDFY4 LYST

6.99e-0498121230
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

MID2 TRIM27 TRIM22 MID1

8.73e-049581459
GeneFamilyProtein phosphatase catalytic subunits|EF-hand domain containing

PPP2CA PPP2CB

1.50e-0313812693
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ4 KCNJ14

2.28e-0316812276
GeneFamilyProtein phosphatase catalytic subunits|STRIPAK complex

PPP2CA PPP2CB

3.57e-03208121371
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

WAPL RNF19A HIPK1 PARP8 FBXO11 YTHDC2 KBTBD2 ARID1A LYST TRIM22 FCRL6 PACS1 ZBTB44 SF3B1 ERAP2 CCNL1 EPC1 SEL1L3 CD47 KMT2A PCBP1 SNRNP200 VPS13B KPNB1

8.55e-08149212224M40023
CoexpressionNABA_CORE_MATRISOME

COL4A3 COL4A5 COL4A6 LAMC3 VWDE OTOGL COL14A1 PRG4 CRISPLD1

5.06e-062701229MM17057
CoexpressionNABA_CORE_MATRISOME

COL4A3 COL4A5 COL4A6 LAMC3 VWDE COL14A1 PRG4 CRISPLD1 FBN3

5.86e-062751229M5884
CoexpressionGSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_UP

CCNL2 TMEM67 ZSWIM6 USP31 CCNL1 EPC1 SV2C

1.41e-051681227M6704
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A3 COL4A5 COL4A6 LAMC3

3.59e-05401224M5887
CoexpressionGSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN

CXCL10 S1PR2 TRIM22 ATP10D CCNL1 APOL3 CD47

4.33e-052001227M9593
CoexpressionNABA_COLLAGENS

COL4A3 COL4A5 COL4A6 COL14A1

4.79e-05431224MM17060
CoexpressionNABA_COLLAGENS

COL4A3 COL4A5 COL4A6 COL14A1

5.25e-05441224M3005
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 COL4A6 SLC22A23 VEPH1 HHIP CACNA2D3

8.57e-071871227201ff693e4756ee3e44762885b3a303a77eb535b
ToppCell368C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL VEPH1 WDFY4 FCRL6 CPNE3 PADI6

5.49e-0616112261011094c54381d52566e24c92f89f2efc2aa3eea
ToppCell368C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL VEPH1 WDFY4 FCRL6 CPNE3 PADI6

5.89e-061631226299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCellnormal_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RUBCNL WDFY4 CLEC2L KCNJ14 CPNE3 APOL3

6.54e-0616612266210a136efb99d70c2026b6454363f1bd2723558
ToppCell3'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUBCNL EI24 ZBTB44 UHRF1 PCBP1 HSP90AA1

7.00e-061681226b08458164d270d625b8ee390122d1c2ce8c653db
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RUBCNL WDFY4 FCRL6 SLCO5A1 CPNE3 APOL3

7.25e-061691226a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WDFY4 ADCY1 SLCO5A1 CPNE3 APOL3 PADI6

8.56e-061741226991f7eab69ea3ee1045a4e44ce60a96db13df6d1
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

WDFY4 ADCY1 SLCO5A1 CPNE3 APOL3 PADI6

8.56e-061741226c8cec89369cf3896c5626e447051e76a142cb6df
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RUBCNL WDFY4 FCRL6 SLCO5A1 CPNE3 APOL3

8.56e-0617412265ec8a48a390379d6c422120dce46437a77da67cc
ToppCellBAL-Control-cDC_11|Control / Compartment, Disease Groups and Clusters

RUBCNL WDFY4 ADCY1 CPNE3 APOL3 PADI6

8.84e-061751226daf014e15a354956e9149c83fd89d0af0d07eb00
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

CXCL10 MKRN1 TRIM22 VWDE ERAP2 HSP90AA1

9.43e-061771226a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCD S1PR2 PTCH1 HHIP KCNJ4 COL14A1

9.74e-06178122627497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCD S1PR2 PTCH1 HHIP KCNJ4 COL14A1

9.74e-061781226d348a9550db940d204706529759dc51e30506b5f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A5 COL4A6 GRIN2A SEL1L3 CACNA2D3

1.07e-0518112269d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A5 COL4A6 GRIN2A SEL1L3 CACNA2D3

1.11e-051821226eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 COL4A6 SLC22A23 VEPH1 CACNA2D3

1.18e-0518412267cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL4A6 VWC2 GRIN2A HHIP PRG4 CACNA2D3

1.21e-051851226492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell367C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL WDFY4 FCRL6 SLCO5A1 CPNE3 PADI6

1.29e-0518712263748203b62abf51b74dfcfc4f18b3ba831b63a96
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 COL4A6 SLC22A23 VEPH1 CACNA2D3

1.29e-05187122658d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL4A3 VWC2 THSD7B SLCO5A1 SV2C COL14A1

1.33e-0518812268268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellLPS-IL1RA-Epithelial_alveolar|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 COL4A6 VEPH1 HHIP CACNA2D3

1.33e-0518812266164d467b612767ceba15de34176bcc8e8c36ab8
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 COL4A6 SLC22A23 VEPH1 CACNA2D3

1.33e-05188122643a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FBXO11 ZSWIM6 PPP2CB CCNL1 COL14A1 HSP90AA1

1.50e-0519212266bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RNF19A HIPK1 SLC22A23 MEIKIN FBXO30 STRADB

1.54e-051931226be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TSPAN15 GRIN2A THSD7B USP31 SEL1L3 APOL3

1.59e-05194122632ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HIPK1 MEIKIN MKRN1 FBXO30 STRADB SV2C

1.83e-051991226565404c155dfac57c020a8f2d09cbf756da20ffd
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HIPK1 MEIKIN MKRN1 FBXO30 STRADB SV2C

1.83e-0519912266c174dbcc25b980f10a3d1dfe39e613acac73bb6
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HIPK1 MEIKIN MKRN1 FBXO30 STRADB SV2C

1.83e-051991226284ee9632413f6404fc0b0c7c393ad813db834f2
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

COL4A5 COL4A6 ARID1A ZBTB44 PPP2CB KMT2A

1.83e-051991226358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellVE|World / Condition, Cell_class and T cell subcluster

RNF19A PARP8 TRIM22 SF3B1 KMT2A HSP90AA1

1.89e-0520012268ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellCOVID-19|World / Disease, condition lineage and cell class

RNF19A SF3B1 CCNL1 EPC1 KMT2A HSP90AA1

1.89e-0520012267dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF19A PARP8 LYST TRIM22 PCBP1 RNF138

1.89e-05200122648d79c7a9a2d3c10b41e152baf28fb00a4729e48
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

CYP1A1 LAMC3 THSD7B CSMD3 FBN3

2.84e-05129122557b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

CXCL10 GUCY1B2 CCT6B ZPBP2

3.88e-0569122454e5ede00ce2920158d1cc0ac8e718aa24a4342e
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CXCL10 GUCY1B2 CCT6B ZPBP2

3.88e-05691224c93a47ee777b560f69b705d5d597f3cb3a3f558a
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

CXCL10 GUCY1B2 CCT6B ZPBP2

3.88e-056912248946d7e433c232c56563a6c464152c0a8cdbdf92
ToppCell343B-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL WDFY4 SLCO5A1 CPNE3 APOL3

6.61e-05154122571d33b5dbfab5820e3daddb01806a69116ba8008
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A5 COL4A6 VWDE SLC16A12 MID1

7.24e-0515712256ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

COL4A5 COL4A6 LAMC3 SLC16A12 PASK

8.40e-05162122591cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A5 COL4A6 THSD7B HHIP GPR156

8.64e-0516312251e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

RNF19A VWDE PASK ZBTB44 LINC00173

8.64e-0516312254104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RNF19A RUBCNL SLCO5A1 KCNJ14 PRG4

8.90e-0516412251aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RUBCNL WDFY4 SLCO5A1 OTOGL CPNE3

8.90e-05164122543045879505774ac0d9b7f760557955564f06d00
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

GABRB3 SGCD PTCH1 FCRL6 PADI6

8.90e-05164122560fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_2|Striatum / BrainAtlas - Mouse McCarroll V32

PASK GUCY1B2 UHRF1 PCBP1

9.20e-058612242df674969383d93509ea9e201452cfda702fae40
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4|Striatum / BrainAtlas - Mouse McCarroll V32

PASK GUCY1B2 UHRF1 PCBP1

9.20e-058612248ead39a100fa5aedf93a2206edd9828538f990a5
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

RUBCNL WDFY4 SLCO5A1 CPNE3 APOL3

9.42e-0516612259f14e3ef19d5903278c040be1c477501237173fa
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

NCAPD3 RUBCNL WDFY4 SLCO5A1 CPNE3

9.42e-0516612250590e404f45afce90e20f93f90a3def83949c66b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMC3 PTCH1 CSMD3 HHIP CACNA2D3

9.42e-0516612253b67064a5149e72f895344d938c64b8ff65247f5
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 VWC2 COL14A1 PRKN PRG4

9.69e-051671225c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 VWC2 COL14A1 PRKN PRG4

9.69e-051671225351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

COL4A3 RUBCNL WDFY4 LINC00173 SEL1L3

9.96e-0516812258e025bb0541746e232b77ac0e31412ae71420c47
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

COL4A3 RUBCNL WDFY4 LINC00173 SEL1L3

9.96e-0516812255535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMC3 PTCH1 CSMD3 HHIP HSP90AA1

1.05e-041701225a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC1|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

WDFY4 KCNJ14 CPNE3 SEL1L3 APOL3

1.08e-04171122504346d4eb726875e3537e215ea081a0318ca4ddd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RUBCNL GRIN2A HHIP LZTS1 KCNJ14

1.08e-0417112252a34685f7d83d1cf9a88d304173cbca868c5f9fd
ToppCell356C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL WDFY4 FCRL6 SLCO5A1 CPNE3

1.08e-0417112253d60e7ecf25e4b781ba2387671b2aad247fb75ff
ToppCellsevere_influenza-B_memory|World / disease group, cell group and cell class (v2)

COL4A3 RUBCNL HHIP SEL1L3 GPR156

1.11e-0417212250ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 RUBCNL WDFY4 CCT6B UHRF1

1.14e-04173122520a20429aa898097d5ec4880ed64846558b5890f
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A5 COL4A6 CXCL10 LAMC3 SLC16A12

1.17e-0417412252891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A5 COL4A6 CXCL10 LAMC3 SLC16A12

1.17e-041741225eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 GRIN2A CSMD3 ADCY1 FBN3

1.24e-0417612256c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|metastatic_Brain / Location, Cell class and cell subclass

RUBCNL WDFY4 TRIM22 CPNE3 APOL3

1.24e-041761225b9ba7026dee2272c0b483dc0cfa39f74b75f1634
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A5 TMEM67 PTCH1 HHIP PRKN

1.27e-041771225e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 SLC22A23 VEPH1 CACNA2D3

1.27e-0417712259af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD141+_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

MEIKIN RUBCNL WDFY4 CPNE3 APOL3

1.34e-04179122599894067e2c2a3ed53abdc5434410c3172693496
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 SLC22A23 VEPH1 CACNA2D3

1.34e-04179122504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RUBCNL WDFY4 SLCO5A1 ERAP2 SEL1L3

1.38e-04180122565c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A5 COL4A6 THSD7B PTCH1 HHIP

1.41e-04181122525915e2500430a902db37d79a749ce2990b69810
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-cDC1|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUBCNL WDFY4 SLCO5A1 CPNE3 APOL3

1.41e-04181122584ca8c9c036478a6d3a2071919d09065455d417c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 SLC22A23 VEPH1 CACNA2D3

1.41e-041811225b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

COL4A5 COL4A6 SLC22A23 USP31 PLIN5

1.45e-041821225759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCellControl-Epithelial_alveolar-AT_2-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 COL4A6 VEPH1 HHIP CACNA2D3

1.45e-041821225e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A3 RUBCNL WDFY4 ATP10D SEL1L3

1.45e-041821225ccd729388d997cc45071175cb0c3db6d0790eaf8
ToppCell367C-Myeloid-Dendritic-cDC1|367C / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL WDFY4 SLCO5A1 CPNE3 PADI6

1.45e-0418212256f5228ac47f9ab46d165740cf2655b5ba217acbe
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-cDC1|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUBCNL WDFY4 LHB SLCO5A1 CPNE3

1.49e-041831225661bfc8f5f683b0f4c12bdd359e67c513b181678
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC22A23 PLIN5 APOL3 CD47 SV2C

1.49e-041831225a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC22A23 PLIN5 APOL3 CD47 SV2C

1.49e-04183122513ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 SLC22A23 VEPH1 CACNA2D3

1.53e-04184122542ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A3 RUBCNL WDFY4 ATP10D SEL1L3

1.53e-041841225d18e94839a62fca536ae1630c154e5d0aafc44c5
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 COL4A6 VEPH1 HHIP CACNA2D3

1.53e-04184122551e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RUBCNL WDFY4 FCRL6 SLCO5A1 CPNE3

1.53e-041841225667846c422cfa27e949a24844a305df859cb6760
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GABRB3 COL4A3 VWC2 COL14A1 CACNA2D3

1.53e-0418412258fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

RNF19A PARP8 ADCY1 SEL1L3 VPS13B

1.53e-0418412259c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RUBCNL WDFY4 FCRL6 SLCO5A1 CPNE3

1.53e-041841225a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 SLC22A23 VEPH1 CACNA2D3

1.53e-041841225cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 COL4A6 SLC22A23 HHIP CACNA2D3

1.53e-041841225ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 COL4A6 VEPH1 HHIP CACNA2D3

1.56e-0418512250d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A3 RUBCNL WDFY4 SLCO5A1 SEL1L3

1.56e-04185122505e6eb78ead81268c1656e7ffe34f9cb7329b908
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 COL4A6 VEPH1 HHIP CACNA2D3

1.56e-0418512258ca1374501eca01d8468130b74d50abfd4329fbe
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 COL4A6 VEPH1 CACNA2D3

1.56e-0418512253937e026add96a396122139daf8011cfbc60e75c
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGCD LAMC3 ADCY1 HHIP CCL8

1.56e-041851225e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGCD LAMC3 ADCY1 HHIP CCL8

1.56e-0418512259d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 SLC22A23 VEPH1 CACNA2D3

1.60e-0418612254e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 SLC22A23 VEPH1 CACNA2D3

1.60e-0418612253aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell10x5'-Liver-Myeloid_Dendritic-DC1|Liver / Manually curated celltypes from each tissue

RUBCNL WDFY4 SLCO5A1 CLEC2L CPNE3

1.60e-041861225e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL4A6 GRIN2A HHIP OTOGL CACNA2D3

1.64e-0418712258e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCell(1)_B_CD27pos|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

COL4A3 RUBCNL WDFY4 KLHL7 SEL1L3

1.64e-041871225bb189942123eb03dd6505f1af8771dd7285bb8b9
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SLC22A23 THSD7B LYST MID1 TBCK

1.64e-041871225f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A5 SLC16A12 SEL1L3 CACNA2D3

1.64e-041871225c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
Diseasecollagen disease (implicated_via_orthology)

COL4A3 COL4A5 COL4A6

1.27e-05121163DOID:854 (implicated_via_orthology)
DiseaseLeiomyomatosis, esophageal and vulval, with nephropathy

COL4A5 COL4A6

1.53e-0521162C1839884
DiseaseLeiomyoma, Epithelioid

COL4A5 COL4A6

1.53e-0521162C0086533
DiseaseAlport syndrome (is_implicated_in)

COL4A3 COL4A5

4.58e-0531162DOID:10983 (is_implicated_in)
DiseaseAlport syndrome

COL4A3 COL4A5

4.58e-0531162cv:C1567741
DiseaseCollagen IV-related nephropathies

COL4A3 COL4A5

4.58e-0531162cv:CN076135
DiseaseChediak-Higashi syndrome (implicated_via_orthology)

WDFY4 LYST

9.15e-0541162DOID:2935 (implicated_via_orthology)
DiseaseHematuria, Benign Familial

COL4A3 COL4A5

9.15e-0541162C0241908
DiseaseAlport Syndrome

COL4A3 COL4A5

9.15e-0541162C1567741
DiseaseAlport Syndrome, X-Linked

COL4A3 COL4A5

1.52e-0451162C1567742
DiseaseAlport Syndrome, Autosomal Dominant

COL4A3 COL4A5

1.52e-0451162C1567743
DiseaseAlport Syndrome, Autosomal Recessive

COL4A3 COL4A5

1.52e-0451162C1567744
DiseaseOpitz GBBB syndrome (implicated_via_orthology)

MID2 MID1

2.27e-0461162DOID:0080697 (implicated_via_orthology)
DiseaseBurkitt Lymphoma

ARID1A CCT6B KMT2A

3.85e-04361163C0006413
DiseaseAutistic Disorder

GABRB3 GRIN2A CSMD3 WDFY4 PASK PRKN

5.96e-042611166C0004352
Diseaseserum alanine aminotransferase measurement

DIP2B EI24 S1PR2 PTCH1 ARID1A ATP10D PRUNE1 HHIP LZTS1 APOL3 PRKN

6.43e-0486911611EFO_0004735
Diseasecervical carcinoma

SLCO5A1 LZTS1 ZPBP2 EXOC1 TRDMT1

7.80e-041821165EFO_0001061
Diseasequality of life during menstruation measurement, dysmenorrheic pain measurement

GRIN2A VPS13B

8.23e-04111162EFO_0007889, EFO_0009366
DiseaseGastrointestinal Stromal Sarcoma

HIPK1 PTCH1 HHIP

8.46e-04471163C3179349
Diseaserisk-taking behaviour

PARP8 MKRN1 FBXO11 GRIN2A THSD7B PTCH1 TRIM27 RGS3 KCNJ4 CD47

8.85e-0476411610EFO_0008579
Diseasemyopathy (implicated_via_orthology)

COL4A3 COL4A5 COL4A6

9.00e-04481163DOID:423 (implicated_via_orthology)
Diseaseacute myeloid leukemia (implicated_via_orthology)

SF3B1 KMT2A

9.86e-04121162DOID:9119 (implicated_via_orthology)
DiseaseGastrointestinal Stromal Tumors

HIPK1 PTCH1 HHIP

1.01e-03501163C0238198
DiseaseInfluenza

CXCL10 TRIM22 CCL8

1.14e-03521163C0021400
Diseaseesophageal cancer (is_implicated_in)

CYP1A1 LZTS1

1.16e-03131162DOID:5041 (is_implicated_in)
Diseasehematologic cancer (implicated_via_orthology)

PIAS1 PIAS4

1.16e-03131162DOID:2531 (implicated_via_orthology)
Diseasecomplement component C6 measurement

CXCL10 PARP8

1.16e-03131162EFO_0020281
Diseasesmoking status measurement, ulcerative colitis

WDFY4 CCL8

1.16e-03131162EFO_0000729, EFO_0006527
Diseaselifestyle measurement, maximum cigarettes per day measurement

LZTS1 EPC1 CD47 RNF138

1.39e-031221164EFO_0009264, EFO_0010724
DiseaseAfrican Burkitt's lymphoma

ARID1A CCT6B

1.56e-03151162C0343640
DiseaseBurkitt Leukemia

ARID1A CCT6B

1.56e-03151162C4721444
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

VWC2 SGCD CSMD3 PRKN PRG4

1.67e-032161165EFO_0007925, EFO_0007927
Diseaseneuroticism measurement, cognitive function measurement

SGCD SLC22A23 GRIN2A THSD7B PTCH1 ARID1A UHRF1 PRKN

1.81e-035661168EFO_0007660, EFO_0008354
Diseaseintrahepatic cholangiocarcinoma (is_marker_for)

ARID1A HSP90AA1

2.51e-03191162DOID:4928 (is_marker_for)
DiseaseHereditary hearing loss and deafness

COL4A3 COL4A5 S1PR2 ADCY1

2.68e-031461164cv:C0236038
DiseaseManic Disorder

GRIN2A PACS1 CD47

2.79e-03711163C0024713
DiseaseCleft palate

SGCD PTCH1 PRKN

2.79e-03711163HP_0000175
Diseasestomach cancer (is_implicated_in)

CYP1A1 PTCH1 ARID1A

2.90e-03721163DOID:10534 (is_implicated_in)
Diseasepeak expiratory flow

CYP1A1 ZSWIM6 PACS1 HHIP TBCK FBN3 CACNA2D3

3.60e-034981167EFO_0009718
DiseaseManic

GRIN2A PACS1 CD47

3.63e-03781163C0338831
DiseaseRenal glomerular disease

COL4A3 COL4A5

3.67e-03231162C0268731
DiseaseGlomerulopathy Assessment

COL4A3 COL4A5

3.67e-03231162C4521256
Diseasegeneralized anxiety disorder

LAMC3 VWDE

3.67e-03231162EFO_1001892
Diseaseinfant body height

PTCH1 HHIP

3.67e-03231162EFO_0006785
DiseaseDepression, Bipolar

GRIN2A PACS1 CD47

3.77e-03791163C0005587

Protein segments in the cluster

PeptideGeneStartEntry
CLTTLTVPQRCIGFA

EPC1

441

Q9H2F5
SRCSVCEAPSQAIAV

COL4A6

1566

Q14031
TPRCVVVTCPSINSF

CSMD3

2686

Q7Z407
SRCTVCEGPAIAIAV

COL4A3

1546

Q01955
VISVKQCEITVECTF

CPNE3

266

O75131
AREFTTTVVSCCPAE

AARSD1

11

Q9BTE6
DIVSQLPETCIVSCE

AADACL3

331

Q5VUY0
VFVRFQPETIACACI

CCNL1

236

Q9UK58
TPTRQACVDVDECIV

FBN3

481

Q75N90
VVCCRATPLQKSEVV

ATP10D

1026

Q9P241
CPQCRITSNFVIPSE

MKRN4P

366

Q13434
TDVQRPQVVEYCVVC

NR2C2

106

P49116
TVIFPFQTATCRRCS

RUBCNL

611

Q9H714
FTICCDSPVRVQAVD

RGS3

311

P49796
VVSVTNVICAICFGR

CYP1A1

191

P04798
AVAVCRIPVLECAAS

INTS15

121

Q96N11
ITQVVRIACANTFPE

OR4M2B

181

A0A0X1KG70
CVTEECPLAVIAVVV

KCNJ4

141

P48050
CVCVSNTIRSLSFVP

ARID1A

1981

O14497
IFCPHVALQTTICEV

PRUNE1

301

Q86TP1
FESARVECAIQTCPE

MMADHC

141

Q9H3L0
DTVVFRVAPCVFIPC

PADI6

296

Q6TGC4
CSYVQIICTVLRIPS

OR6N1

216

Q8NGY5
PIRCIHTEEVCITSV

CT55

171

Q8WUE5
PTVCERELCVFAFQT

PARP8

526

Q8N3A8
LCCVVVLEPVERVST

PASK

226

Q96RG2
VPQSVTECVKQICLV

PCBP1

151

Q15365
CVRSPISTDECSIQE

LZTS1

251

Q9Y250
ICTQTDPFQQTFIVC

HIPK1

641

Q86Z02
VTISNRLVSSPCCIV

HSP90AB3P

451

Q58FF7
VDPVVSFPVALSCRC

LHB

96

P01229
SIICAEVRCLQPSEV

FCRL6

396

Q6DN72
ITQVVRIACANTFPE

OR4M1

181

Q8NGD0
ITQVVRIACANTFPE

OR4M2

181

Q8NGB6
VPDQCTIEDTVRSCV

VEPH1

571

Q14D04
TRGINLSCVRTCVVV

DIP2B

1271

Q9P265
LSCVRTCVVVAEERP

DIP2B

1276

Q9P265
SDPCVRAVVISNSLC

KBTBD2

521

Q8IY47
FPANASEICCIIRTS

MEIKIN

326

A0A087WXM9
PVLVAVVCCAQSVND

GABRB3

16

P28472
VRAFPVTSCLICVVD

KLHL7

561

Q8IXQ5
VVTSTACVVILPLIC

LRIT3

586

Q3SXY7
KESNVQEVRCPVTVC

PPP2CB

41

P62714
KESNVQEVRCPVTVC

PPP2CA

41

P67775
QRKPVVCTCSTVEVQ

PACS1

586

Q6VY07
TEECPAAVAAVVLQC

KCNJ14

156

Q9UNX9
IANLISCFPSVCVRD

GLYATL3

181

Q5SZD4
ADSVVVLLCRQPCAS

UPF1

201

Q92900
QCFPGCLTIQIRTVL

ADCY1

661

Q08828
VVVDSSCLCESVAPI

CACNA2D3

1011

Q8IZS8
SPIIDHCIIRSTCTV

FBXO11

371

Q86XK2
VFVRFQPESIACACI

CCNL2

231

Q96S94
ITFVCETASATCPVV

COL14A1

1206

Q05707
VQAVTCETTVEQLCP

CRISPLD1

391

Q9H336
QESEPRIVSRIFQCC

EI24

61

O14681
RTVRCTCISISNQPV

CXCL10

26

P02778
SIQPFISRCAVCEAP

COL4A5

1556

P29400
ISRCAVCEAPAVVIA

COL4A5

1561

P29400
DSVSIPITCCFNVIN

CCL8

26

P80075
CLIRSCCQVVTFTFP

APOL3

16

O95236
CREIICSVAFSNQPE

LYST

3701

Q99698
CCRQFENVAVIPTVF

MS4A18

281

Q3C1V0
VVCEATQCPDTRVRV

KPNB1

221

Q14974
TAILPQICICSQFSV

ERAP2

26

Q6P179
IFVCTTTINCFIFIP

GPR156

296

Q8NFN8
VPITPRVVCFLCASS

KMT2A

1426

Q03164
CFLCATVTTERPVQV

EXOC1

36

Q9NV70
VVVSNRLVTSPCCIV

HSP90AA1

586

P07900
TFCNDTVVIPCFVTN

CD47

31

Q08722
PCVSTVLVEPARNCV

FBXO30

591

Q8TB52
TSRQVASAFIVILCC

S1PR2

31

O95136
SSSCELPLVAVCQVT

NIT1

41

Q86X76
PIDFRTQISFCAVVC

OTOGL

731

Q3ZCN5
CPECRITSNFVIPSE

MKRN1

331

Q9UHC7
VRCEPTFVNTSRSCA

TMEM67

171

Q5HYA8
TAETNVSCPQCRETF

TRIM27

46

P14373
TFIEECVNPCSVTLL

CCT6B

361

Q92526
DIVQPTCRRSVCFTK

TRDMT1

281

O14717
VSEVSVEYLCSQPCV

SEL1L3

96

Q68CR1
VFVIVCALPCVSSVV

SV2C

321

Q496J9
ITCITCTDVRSPVLV

PRKN

236

O60260
CTDVRSPVLVFQCNS

PRKN

241

O60260
CTRAVTRCISIFFVE

SLC16A12

61

Q6ZSM3
VFFCAEITPTVIRCG

SLC22A23

556

A1A5C7
DVVTFTNICTACEPI

GUCY1B2

396

O75343
FCCFTSPCVSRVIQV

PTCH1

611

Q13635
CQEVLKTPVRTTACQ

RNF138

21

Q8WVD3
CTCVQSRQVITPPTV

SLCO5A1

601

Q9H2Y9
CPICRQTVTLLLTVF

RNF170

126

Q96K19
VQVQLRFCLSETSCP

PIAS1

196

O75925
CFCIQEVVSGLRQPV

HHIP

216

Q96QV1
IPSPIDTVFTRCNCE

PRG4

1191

Q92954
ELCVFPDRFVVCVSQ

SLX4IP

106

Q5VYV7
VVVCDQVSACIPVFR

ALG2

111

Q9H553
ECVFVEPTRLVSTEC

CLEC2L

186

P0C7M8
PQCVQNCIEVFVSLT

NCAPD3

236

P42695
STTKDCCLFQIPVSV

VWDE

121

Q8N2E2
TVCVCFNSRVQLTVP

LINC00173

11

Q6ZV60
ICCATVATAVEQYVP

TMEM59

256

Q9BXS4
QTLEEFVVSPCERCR

VWC2

226

Q2TAL6
EISESRVNISCPECT

RNF19A

166

Q9NV58
CVVVVNPQTKRSRCF

HNRNPA0

36

Q13151
CTTVAIAIVAETCSP

SF3B1

1111

O75533
TPTGTRQKVFEICVC

SGCD

251

Q92629
ESVESITAFQCPTCR

MID1

46

O15344
ITAFQCPTCRHVITL

MID1

51

O15344
VPYTCCIRNTTEVVN

TSPAN15

181

O95858
ECSVVERTIPVCRES

ZBTB44

166

Q8NCP5
RTEQPFVCFSVSLCP

WDFY4

1101

Q6ZS81
CLCQESPINVTTVRE

WAPL

1131

Q7Z5K2
KPVSCSTVLCIAFEV

TBCK

86

Q8TEA7
VVLRICYSDTSCPQE

PIAS4

191

Q8N2W9
CKEEISATQIIVCTP

SNRNP200

576

O75643
CCQELVFRPITTVCQ

UHRF1

726

Q96T88
IANIRCCSAVTPVTI

YTHDC2

1046

Q9H6S0
EPETVCNVAISFDRC

ZSWIM6

241

Q9HCJ5
APEAQRETVFVCASC

ZFYVE27

391

Q5T4F4
VTPTALAACTRVDSC

VPS13B

2456

Q7Z7G8
CFCTSRTQVESLRPE

STRADB

6

Q9C0K7
VVALPLVRATCTAVC

PLIN5

26

Q00G26
VCIQVCPFSLRVVSV

USP31

506

Q70CQ4
VQECTVPCREDCTFT

THSD7B

861

Q9C0I4
ESIEPITAFQCPTCR

MID2

66

Q9UJV3
SVIISRGESSCPVCQ

TRIM22

46

Q8IYM9
PDVNVTCQTCVSVLT

ZPBP2

306

Q6X784
VCRIPLSAEFTAQCT

PRO3102

26

Q9H379
SACTTIPESREVVCT

LAMC3

761

Q9Y6N6
TETCVRNTVPCRKFV

GRIN2A

426

Q12879