Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

SPNS1 SLC36A1 ATP8B4 GJD2 TMEM241 ATP7A PSEN1 SLC39A2 GJC1 ATP9B GRIN2A GRIN2B SLC18B1 SLC22A17 SLC16A12 CALHM4 SLC3A1 SLC6A12 CLCN3 SLC16A2 SLC25A2 SLC25A15 SCNN1A ANO7 ATP12A SVOP MFSD1

1.15e-09128911027GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SPNS1 SLC36A1 GJD2 TMEM241 ATP7A PSEN1 SLC39A2 GJC1 GRIN2A GRIN2B SLC18B1 SLC22A17 SLC16A12 CALHM4 SLC3A1 SLC6A12 CLCN3 SLC16A2 SLC25A2 SLC25A15 SCNN1A ANO7 ATP12A SVOP MFSD1

4.31e-09118011025GO:0022857
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC36A1 GRIN2A GRIN2B SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15

1.17e-071051108GO:0015171
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC36A1 GRIN2A GRIN2B SLC16A12 SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15

2.18e-062071109GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC36A1 GRIN2A GRIN2B SLC16A12 SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15

2.27e-062081109GO:0005342
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC36A1 TMEM241 GRIN2A GRIN2B SLC16A12 SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15

5.11e-0629311010GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC36A1 TMEM241 SLC18B1 SLC16A12 SLC6A12 CLCN3 SLC16A2 SLC25A2 SLC25A15 MFSD1

5.59e-0629611010GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC36A1 TMEM241 ATP7A SLC18B1 SLC16A12 SLC6A12 CLCN3 SLC16A2 SLC25A2 SLC25A15 ATP12A MFSD1

1.27e-0547711012GO:0022804
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC36A1 ATP7A PSEN1 SLC39A2 GJC1 GRIN2A GRIN2B SLC18B1 CALHM4 SLC6A12 CLCN3 SCNN1A ANO7 ATP12A

1.16e-0479311014GO:0015075
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC3A1 SLC25A2 SLC25A15

1.73e-04201103GO:0015174
GeneOntologyMolecularFunctionL-ornithine transmembrane transporter activity

SLC25A2 SLC25A15

2.97e-0451102GO:0000064
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIN2A GRIN2B

6.20e-0471102GO:0005234
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC36A1 SLC3A1 SLC25A2 SLC25A15

6.38e-04711104GO:0015179
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2A GRIN2B

8.24e-0481102GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2A GRIN2B

8.24e-0481102GO:0004972
GeneOntologyMolecularFunctionaromatase activity

CYP2C8 CYP2C18 CYP4B1

9.36e-04351103GO:0070330
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC36A1 ATP7A PSEN1 SLC39A2 GRIN2A GRIN2B SLC18B1 SLC6A12 CLCN3 SCNN1A ANO7 ATP12A

9.59e-0475811012GO:0015318
GeneOntologyMolecularFunctionantiporter activity

TMEM241 SLC18B1 CLCN3 SLC25A2 SLC25A15

1.00e-031381105GO:0015297
GeneOntologyMolecularFunctionL-lysine transmembrane transporter activity

SLC25A2 SLC25A15

1.06e-0391102GO:0015189
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC36A1 ATP7A PSEN1 SLC39A2 GRIN2A GRIN2B SLC18B1 CALHM4 SLC6A12 SCNN1A ATP12A

1.09e-0366411011GO:0008324
GeneOntologyMolecularFunctionuniporter activity

SLC16A12 MFSD1

1.31e-03101102GO:0015292
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC25A2 SLC25A15

2.25e-03131102GO:0061459
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC36A1 ATP7A PSEN1 SLC39A2 GRIN2A GRIN2B SLC18B1 SLC6A12 SCNN1A ATP12A

2.44e-0362711010GO:0022890
GeneOntologyMolecularFunctionchannel activity

GJD2 PSEN1 GJC1 GRIN2A GRIN2B CALHM4 CLCN3 SCNN1A ANO7

2.49e-035251109GO:0015267
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP2C8 CYP2C18 CYP4B1

2.49e-03491103GO:0016712
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GJD2 PSEN1 GJC1 GRIN2A GRIN2B CALHM4 CLCN3 SCNN1A ANO7

2.52e-035261109GO:0022803
GeneOntologyMolecularFunctionglutamate binding

GRIN2A GRIN2B

2.62e-03141102GO:0016595
GeneOntologyMolecularFunctionretinoic acid 4-hydroxylase activity

CYP2C8 CYP2C18

2.62e-03141102GO:0008401
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ATP8B4 ATP9B ANO7

2.80e-03511103GO:0140303
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC36A1 PSEN1 SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15

3.67e-061201107GO:0003333
GeneOntologyBiologicalProcessamino acid transport

SLC36A1 PSEN1 GRIN2B SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15

9.94e-061951108GO:0006865
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC36A1 ATP7A CHERP PSEN1 HECW1 SLC39A2 GJC1 SPG11 GRIN2A GRIN2B TRDN SLC18B1 SLC22A17 CALHM4 TG HPCA SLC6A12 CLCN3 SCNN1A ANO7 ATP12A

1.05e-05137411021GO:0006811
GeneOntologyBiologicalProcessorganic anion transport

SLC36A1 CYB5RL TMEM241 PSEN1 GRIN2B SLC16A12 SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15 PLA2G4F

1.98e-0551511012GO:0015711
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC36A1 ATP7A CHERP PSEN1 HECW1 SLC39A2 GJC1 GRIN2A GRIN2B TRDN SLC18B1 CALHM4 HPCA SLC6A12 CLCN3 SCNN1A ANO7 ATP12A

2.40e-05111511018GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC36A1 ATP7A CHERP PSEN1 HECW1 SLC39A2 SPG11 GRIN2A GRIN2B TRDN SLC18B1 SLC22A17 CALHM4 HPCA SLC6A12 CLCN3 SCNN1A ATP12A

3.90e-05115711018GO:0006812
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC36A1 ATP7A CHERP PSEN1 HECW1 SLC39A2 GRIN2A GRIN2B TRDN SLC18B1 CALHM4 HPCA SLC6A12 CLCN3 SCNN1A ATP12A

3.91e-0594211016GO:0098655
GeneOntologyBiologicalProcessimport into cell

SLC36A1 PSEN1 ATP9B SPG11 LRP1B SLC18B1 GSN HPCA SLC6A12 CLCN3 RHOBTB1 SLC16A2 WASHC5 SCNN1A ROCK1 CTBP1 ATP12A

5.30e-05107411017GO:0098657
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC36A1 PSEN1 GRIN2B SLC16A12 SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15 PLA2G4F

6.91e-0541011010GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC36A1 PSEN1 GRIN2B SLC16A12 SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15 PLA2G4F

7.19e-0541211010GO:0015849
GeneOntologyBiologicalProcessmitochondrial L-ornithine transmembrane transport

SLC25A2 SLC25A15

8.43e-0531102GO:1990575
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC36A1 ATP7A CHERP PSEN1 HECW1 SLC39A2 GRIN2A GRIN2B TRDN SLC18B1 HPCA SLC6A12 CLCN3 SCNN1A ANO7 ATP12A

9.66e-05101711016GO:0098660
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC36A1 PSEN1 SLC3A1 SLC25A2 SLC25A15

1.03e-04871105GO:1902475
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC36A1 ATP7A CHERP PSEN1 HECW1 SLC39A2 GRIN2A GRIN2B TRDN SLC18B1 HPCA SLC6A12 CLCN3 SCNN1A ATP12A

1.13e-0492211015GO:0098662
GeneOntologyBiologicalProcessserotonin metabolic process

ATP7A SRD5A1 GRIN2A

1.14e-04181103GO:0042428
GeneOntologyBiologicalProcessphenol-containing compound metabolic process

ATP7A SRD5A1 DBH GRIN2A TG SLC16A2

1.14e-041421106GO:0018958
GeneOntologyBiologicalProcessorganic cation transport

SLC36A1 PSEN1 SLC18B1 SLC6A12 SLC25A2 SLC25A15

1.28e-041451106GO:0015695
GeneOntologyBiologicalProcessbasic amino acid transmembrane transport

SLC3A1 SLC25A2 SLC25A15

1.34e-04191103GO:1990822
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

CYP2C8 ATP7A CYP2C18 PNLIP SRD5A1 DBH GRIN2A H6PD TG SLC16A2 LPCAT3 MOGAT3

1.60e-0464111012GO:1901615
GeneOntologyBiologicalProcessbasic amino acid transport

SLC3A1 SLC25A2 SLC25A15

2.11e-04221103GO:0015802
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC36A1 PSEN1 SLC16A12 SLC3A1 SLC25A2 SLC25A15

2.42e-041631106GO:1905039
GeneOntologyBiologicalProcessprimary amino compound metabolic process

ATP7A SRD5A1 GRIN2A

2.42e-04231103GO:1901160
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC36A1 PSEN1 SLC16A12 SLC3A1 SLC25A2 SLC25A15

2.75e-041671106GO:1903825
GeneOntologyBiologicalProcessL-amino acid transport

SLC36A1 PSEN1 SLC3A1 SLC25A2 SLC25A15

2.84e-041081105GO:0015807
GeneOntologyBiologicalProcessL-ornithine transmembrane transport

SLC25A2 SLC25A15

4.17e-0461102GO:1903352
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

SPNS1 ATP7A CHERP PSEN1 GRIN2B TRDN SLC22A17 ADCY8 CLCN3 SCNN1A ATP12A

4.23e-0461111011GO:0030003
GeneOntologyBiologicalProcessmemory

PSEN1 SPG11 DBH GRIN2A GRIN2B ADCY8

4.49e-041831106GO:0007613
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

SPNS1 ATP7A CHERP PSEN1 GRIN2B TRDN SLC22A17 ADCY8 CLCN3 SCNN1A ATP12A

4.92e-0462211011GO:0006873
GeneOntologyCellularComponentcell projection membrane

ATP7A GRIN2A SSTR3 SLC3A1 B4GALT1 HPCA CLCN3 ENTPD2 SCNN1A PLA2G4F TCTN2

2.04e-0543111211GO:0031253
GeneOntologyCellularComponentendoplasmic reticulum membrane

CYP2C8 CYB5RL TMED6 CYP2C18 CHERP PSEN1 CYP4B1 SRD5A1 GJC1 GRIN2A GRIN2B TRDN LMF2 LPCAT3 ENTPD2 VPS13A MOGAT3 ALOX5AP CERS4

5.42e-05129311219GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

CYP2C8 CYB5RL TMED6 CYP2C18 CHERP PSEN1 CYP4B1 SRD5A1 GJC1 GRIN2A GRIN2B TRDN LMF2 LPCAT3 ENTPD2 VPS13A MOGAT3 ALOX5AP CERS4

5.76e-05129911219GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

CYP2C8 CYB5RL TMED6 CYP2C18 CHERP PSEN1 CYP4B1 SRD5A1 GJC1 GRIN2A GRIN2B TRDN LMF2 LPCAT3 ENTPD2 VPS13A MOGAT3 ALOX5AP CERS4

7.66e-05132711219GO:0042175
GeneOntologyCellularComponentpresynapse

PSEN1 ROR1 DBH GRIN2A GRIN2B SLC18B1 ADCY8 PPP1CA PPP1CC SLC6A12 CLCN3 CTBP1 CTBP2 SVOP

2.76e-0488611214GO:0098793
GeneOntologyCellularComponentvacuolar membrane

SPNS1 SLC36A1 PSEN1 SPG11 SLC22A17 SLC3A1 B4GALT1 CLCN3 VPS13A MFSD1

4.00e-0450711210GO:0005774
GeneOntologyCellularComponentPTW/PP1 phosphatase complex

PPP1CA PPP1CC

5.87e-0471122GO:0072357
GeneOntologyCellularComponentsecretory vesicle

ATP8B4 ATP7A PSEN1 KCMF1 DBH GRIN2A GRIN2B SLC18B1 GSN B4GALT1 CLCN3 VPS13A CUZD1 SCNN1A ROCK1 SVOP

9.78e-04124611216GO:0099503
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2A GRIN2B

9.99e-0491122GO:0017146
GeneOntologyCellularComponentvacuole

SPNS1 SLC36A1 PSEN1 SPG11 GRIN2B SLC22A17 SLC3A1 B4GALT1 CLCN3 TAX1BP1 VPS13A MFSD1 CTSO

1.21e-0391311213GO:0005773
GeneOntologyCellularComponentapical plasma membrane

SLC36A1 ATP7A F2RL2 ADCY8 SLC3A1 CLCN3 SLC16A2 SCNN1A ATP12A

1.24e-034871129GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC36A1 ATP7A DBH F2RL2 ADCY8 SLC3A1 CLCN3 SLC16A2 SCNN1A ATP12A

1.31e-0359211210GO:0045177
GeneOntologyCellularComponentcytoplasmic vesicle membrane

NCALD ATP8B4 ATP7A PSEN1 DBH GRIN2A GRIN2B SLC18B1 ADCY8 B4GALT1 CLCN3 RHOBTB1 WASHC5 VPS13A CUZD1 SVOP

1.61e-03130711216GO:0030659
GeneOntologyCellularComponentvesicle membrane

NCALD ATP8B4 ATP7A PSEN1 DBH GRIN2A GRIN2B SLC18B1 ADCY8 B4GALT1 CLCN3 RHOBTB1 WASHC5 VPS13A CUZD1 SVOP

1.85e-03132511216GO:0012506
GeneOntologyCellularComponenttransport vesicle

NCALD ATP7A PSEN1 DBH GRIN2A GRIN2B SLC18B1 CLCN3 SVOP

1.92e-035191129GO:0030133
DomainMFS_1

SPNS1 SLC18B1 SLC22A17 SLC16A12 SLC16A2 SVOP MFSD1

3.26e-07771097PF07690
DomainMFS

SPNS1 SLC18B1 SLC22A17 SLC16A12 SLC16A2 SVOP MFSD1

3.26e-07771097IPR011701
DomainMFS

SPNS1 SLC18B1 SLC22A17 SLC16A12 SLC16A2 SVOP MFSD1

3.26e-061081097PS50850
DomainMFS_dom

SPNS1 SLC18B1 SLC22A17 SLC16A12 SLC16A2 SVOP MFSD1

1.36e-051341097IPR020846
Domain-

ATP8B4 ATP7A ATP9B ATP12A

3.48e-053210943.40.1110.10
Domain-

ATP8B4 ATP7A ATP9B ATP12A

3.48e-053210942.70.150.10
DomainATPase_P-typ_cyto_domN

ATP8B4 ATP7A ATP9B ATP12A

5.00e-05351094IPR023299
DomainRecoverin

NCALD HPCA HPCAL1

5.30e-05131093IPR028846
DomainP_typ_ATPase

ATP8B4 ATP7A ATP9B ATP12A

5.60e-05361094IPR001757
DomainATPase_P-typ_P_site

ATP8B4 ATP7A ATP9B ATP12A

5.60e-05361094IPR018303
DomainATPASE_E1_E2

ATP8B4 ATP7A ATP9B ATP12A

5.60e-05361094PS00154
DomainATPase_P-typ_transduc_dom_A

ATP8B4 ATP7A ATP9B ATP12A

6.25e-05371094IPR008250
DomainE1-E2_ATPase

ATP8B4 ATP7A ATP9B ATP12A

6.25e-05371094PF00122
DomainNMDAR2_C

GRIN2A GRIN2B

1.01e-0431092PF10565
DomainSTPPase_N

PPP1CA PPP1CC

1.01e-0431092IPR031675
DomainSTPPase_N

PPP1CA PPP1CC

1.01e-0431092PF16891
DomainNMDAR2_C

GRIN2A GRIN2B

1.01e-0431092IPR018884
DomainD_2_HYDROXYACID_DH_2

CTBP1 CTBP2

2.01e-0441092PS00670
DomainD_2_HYDROXYACID_DH_3

CTBP1 CTBP2

2.01e-0441092PS00671
Domain2-Hacid_dh_C

CTBP1 CTBP2

2.01e-0441092PF02826
DomainD-isomer_2_OHA_DH_cat_dom

CTBP1 CTBP2

2.01e-0441092IPR006139
DomainD-isomer_DH_CS

CTBP1 CTBP2

2.01e-0441092IPR029753
Domain2-Hacid_dh

CTBP1 CTBP2

2.01e-0441092PF00389
DomainD_2_HYDROXYACID_DH_1

CTBP1 CTBP2

2.01e-0441092PS00065
DomainD-isomer_DH_NAD-bd

CTBP1 CTBP2

3.34e-0451092IPR006140
DomainHAD-like_dom

ATP8B4 ATP7A ATP9B ATP12A

1.18e-03791094IPR023214
DomainCyt_P450_E_grp-I

CYP2C8 CYP2C18 CYP4B1

2.30e-03451093IPR002401
DomainSer/Thr-sp_prot-phosphatase

PPP1CA PPP1CC

2.52e-03131092IPR006186
DomainSER_THR_PHOSPHATASE

PPP1CA PPP1CC

2.52e-03131092PS00125
DomainPP2Ac

PPP1CA PPP1CC

2.52e-03131092SM00156
DomainP_typ_ATPase_c

ATP8B4 ATP9B

2.93e-03141092IPR032630
DomainP-type_ATPase_N

ATP8B4 ATP9B

2.93e-03141092IPR032631
DomainP-type_ATPase_IV

ATP8B4 ATP9B

2.93e-03141092IPR006539
DomainPhoLip_ATPase_C

ATP8B4 ATP9B

2.93e-03141092PF16212
DomainPhoLip_ATPase_N

ATP8B4 ATP9B

2.93e-03141092PF16209
DomainCyt_P450_CS

CYP2C8 CYP2C18 CYP4B1

3.66e-03531093IPR017972
DomainCYTOCHROME_P450

CYP2C8 CYP2C18 CYP4B1

4.50e-03571093PS00086
Domain-

CYP2C8 CYP2C18 CYP4B1

4.73e-035810931.10.630.10
Domainp450

CYP2C8 CYP2C18 CYP4B1

4.73e-03581093PF00067
DomainIontro_rcpt

GRIN2A GRIN2B

4.86e-03181092IPR001320
DomainLig_chan-Glu_bd

GRIN2A GRIN2B

4.86e-03181092PF10613
DomainIono_rcpt_met

GRIN2A GRIN2B

4.86e-03181092IPR001508
DomainGlu/Gly-bd

GRIN2A GRIN2B

4.86e-03181092IPR019594
DomainLig_chan-Glu_bd

GRIN2A GRIN2B

4.86e-03181092SM00918
DomainLig_chan

GRIN2A GRIN2B

4.86e-03181092PF00060
DomainPBPe

GRIN2A GRIN2B

4.86e-03181092SM00079
DomainCyt_P450

CYP2C8 CYP2C18 CYP4B1

5.20e-03601093IPR001128
DomainCONNEXINS_1

GJD2 GJC1

5.41e-03191092PS00407
DomainCONNEXINS_2

GJD2 GJC1

5.99e-03201092PS00408
DomainConnexin

GJD2 GJC1

5.99e-03201092IPR000500
DomainConnexin_CCC

GJD2 GJC1

5.99e-03201092IPR019570
DomainConnexin_N

GJD2 GJC1

5.99e-03201092IPR013092
DomainConnexin

GJD2 GJC1

5.99e-03201092PF00029
DomainConnexin_CCC

GJD2 GJC1

5.99e-03201092SM01089
DomainConnexin_CS

GJD2 GJC1

5.99e-03201092IPR017990
DomainCNX

GJD2 GJC1

5.99e-03201092SM00037
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC36A1 ATP8B4 CYB5RL ATP7A SLC39A2 ATP9B TRDN SLC22A17 ADCY8 SLC3A1 SLC6A12 LMF2 CLCN3 SLC16A2 SCNN1A ANO7 ATP12A

4.01e-067369117M27287
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP8B4 ATP7A ATP9B TRDN CLCN3 SCNN1A ANO7 ATP12A

2.35e-05183918M997
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC36A1 ATP8B4 CYB5RL ATP7A SLC39A2 ATP9B TRDN SLC22A17 SLC3A1 SLC6A12 LMF2 SLC16A2 SCNN1A ANO7 ATP12A

2.80e-056819115MM14985
PathwayKEGG_LONG_TERM_POTENTIATION

GRIN2A GRIN2B ADCY8 PPP1CA PPP1CC

8.72e-0570915M3115
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

GRIN2A ADCY8 PPP1CA PPP1CC

1.37e-0441914M39655
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP8B4 ATP7A ATP9B TRDN SCNN1A ANO7 ATP12A

1.41e-04176917MM15718
PathwayREACTOME_ELECTRIC_TRANSMISSION_ACROSS_GAP_JUNCTIONS

GJD2 GJC1

4.07e-045912M29532
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

4.07e-045912M47667
PathwayREACTOME_ELECTRIC_TRANSMISSION_ACROSS_GAP_JUNCTIONS

GJD2 GJC1

4.07e-045912MM14497
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP8B4 ATP7A ATP9B ATP12A

4.31e-0455914M971
Pubmed

Gene expression in distinct regions of the heart.

CYP2C8 CYP2C18 CYP4B1

1.30e-074112310768437
Pubmed

Identification of Ca2+-dependent binding partners for the neuronal calcium sensor protein neurocalcin delta: interaction with actin, clathrin and tubulin.

NCALD HPCA HPCAL1

3.84e-0610112311964161
Pubmed

ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development.

GSN CTBP1 CTBP2

7.00e-0612112331116980
Pubmed

Cloning and characterization of human ORNT2: a second mitochondrial ornithine transporter that can rescue a defective ORNT1 in patients with the hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, a urea cycle disorder.

SLC25A2 SLC25A15

1.03e-052112212948741
Pubmed

The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain.

GRIN2A GRIN2B

1.03e-052112225131300
Pubmed

Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system.

HPCA HPCAL1

1.03e-05211228387172
Pubmed

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

GRIN2A GRIN2B

1.03e-052112237657442
Pubmed

CTBP1 and CTBP2 mutations underpinning neurological disorders: a systematic review.

CTBP1 CTBP2

1.03e-052112236331689
Pubmed

Individual NMDA receptor GluN2 subunit signaling domains differentially regulate the postnatal maturation of hippocampal excitatory synaptic transmission and plasticity but not dendritic morphology.

GRIN2A GRIN2B

1.03e-052112238813758
Pubmed

Differential spatial expression and subcellular localization of CtBP family members in rodent brain.

CTBP1 CTBP2

1.03e-052112222745816
Pubmed

Dual Role of NMDAR Containing NR2A and NR2B Subunits in Alzheimer's Disease.

GRIN2A GRIN2B

1.03e-052112238731978
Pubmed

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

GRIN2A GRIN2B

1.03e-052112220921396
Pubmed

Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances.

LRP1B VPS13A

1.03e-052112233159041
Pubmed

Cryo-EM structure of CtBP2 confirms tetrameric architecture.

CTBP1 CTBP2

1.03e-052112233264605
Pubmed

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses.

GRIN2A GRIN2B

1.03e-052112230269991
Pubmed

The GRIN2B and GRIN2A Gene Variants Are Associated With Continuous Performance Test Variables in ADHD.

GRIN2A GRIN2B

1.03e-052112227199241
Pubmed

The role of NMDAR subtypes and charge transfer during hippocampal LTP induction.

GRIN2A GRIN2B

1.03e-052112216901514
Pubmed

Downregulation of hippocampal NR2A/2B subunits related to cognitive impairment in a pristane-induced lupus BALB/c mice.

GRIN2A GRIN2B

1.03e-052112231498792
Pubmed

C-Terminal Binding Protein is Involved in Promoting to the Carcinogenesis of Human Glioma.

CTBP1 CTBP2

1.03e-052112227699603
Pubmed

Selective regulation of NR2B by protein phosphatase-1 for the control of the NMDA receptor in neuroprotection.

GRIN2B PPP1CA

1.03e-052112222479519
Pubmed

Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons.

GRIN2A GRIN2B

1.03e-052112232191258
Pubmed

Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses.

GRIN2A GRIN2B

1.03e-052112220696923
Pubmed

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions.

GRIN2A GRIN2B

1.03e-052112231807283
Pubmed

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

GRIN2A GRIN2B

1.03e-052112223618906
Pubmed

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis.

GRIN2A GRIN2B

1.03e-052112226500840
Pubmed

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice.

GRIN2A GRIN2B

1.03e-052112219474217
Pubmed

Chronic early postnatal scream sound stress induces learning deficits and NMDA receptor changes in the hippocampus of adult mice.

GRIN2A GRIN2B

1.03e-052112227015584
Pubmed

Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.

GRIN2A GRIN2B

1.03e-052112219806658
Pubmed

Importance of the GluN2B carboxy-terminal domain for enhancement of social memories.

GRIN2A GRIN2B

1.03e-052112226179233
Pubmed

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.

GRIN2A GRIN2B

1.03e-052112222142193
Pubmed

Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation.

GRIN2A GRIN2B

1.03e-052112233976221
Pubmed

PP-1α and PP-1γ display antagonism and differential roles in tumorigenicity of lung cancer cells.

PPP1CA PPP1CC

1.03e-052112223176181
Pubmed

Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation.

GRIN2A GRIN2B

1.03e-052112216033900
Pubmed

Directional gating of synaptic plasticity by GPCRs and their distinct downstream signalling pathways.

GRIN2A GRIN2B

1.03e-052112222334046
Pubmed

Different functional types of bipolar cells use different gap-junctional proteins.

GJD2 GJC1

1.03e-052112216014731
Pubmed

The role of neuronal connexins 36 and 45 in shaping spontaneous firing patterns in the developing retina.

GJD2 GJC1

1.03e-052112221734291
Pubmed

Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.

CTBP1 CTBP2

1.03e-05211227479821
Pubmed

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.

GRIN2A GRIN2B

1.03e-052112238214768
Pubmed

[Different distribution of NMDA receptor subunits in cortex contributes to selective vulnerability of motor neurons in amyotrophic lateral sclerosis].

GRIN2A GRIN2B

1.03e-052112221503117
Pubmed

Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.

GRIN2A GRIN2B

1.03e-052112218372311
Pubmed

Role of N-methyl-d-aspartate receptor subunits GluN2A and GluN2B in auditory thalamocortical long-term potentiation in adult mice.

GRIN2A GRIN2B

1.03e-052112234197904
Pubmed

Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory.

GRIN2A GRIN2B

1.03e-052112216157280
Pubmed

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors.

GRIN2A GRIN2B

1.03e-052112232247039
Pubmed

N-Methyl-d-aspartic Acid (NMDA) Receptor Is Involved in the Inhibitory Effect of Ketamine on Human Sperm Functions.

GRIN2A GRIN2B

1.03e-052112234830255
Pubmed

Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.

CTBP1 CTBP2

1.03e-052112224657618
Pubmed

Connexins and steroidogenesis in mouse Leydig cells.

GJD2 GJC1

1.03e-052112223458200
Pubmed

NMDA Receptor C-Terminal Domain Signalling in Development, Maturity, and Disease.

GRIN2A GRIN2B

1.03e-052112236232696
Pubmed

Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs.

CYP2C8 CYP2C18

1.03e-052112210487415
Pubmed

CtBPs promote cell survival through the maintenance of mitotic fidelity.

CTBP1 CTBP2

1.03e-052112219506021
Pubmed

Separate functional properties of NMDARs regulate distinct aspects of spatial cognition.

GRIN2A GRIN2B

1.03e-052112229764972
Pubmed

Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

GRIN2A GRIN2B

1.03e-052112227605622
Pubmed

Assembly of human C-terminal binding protein (CtBP) into tetramers.

CTBP1 CTBP2

1.03e-052112229700119
Pubmed

Targeting neuronal gap junctions in mouse retina offers neuroprotection in glaucoma.

GJD2 GJC1

1.03e-052112228604388
Pubmed

Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function.

GRIN2A GRIN2B

1.03e-052112233043365
Pubmed

Opposing action of conantokin-G on synaptically and extrasynaptically-activated NMDA receptors.

GRIN2A GRIN2B

1.03e-052112222306487
Pubmed

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.

GRIN2A GRIN2B

1.03e-052112230355491
Pubmed

Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy.

FAT3 LRP1B

1.03e-052112235069585
Pubmed

N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease.

GRIN2A GRIN2B

1.03e-052112212127670
Pubmed

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

GRIN2A GRIN2B

1.03e-052112220890276
Pubmed

Presenilin-1/γ-secretase controls glutamate release, tyrosine phosphorylation, and surface expression of N-methyl-D-aspartate receptor (NMDAR) subunit GluN2B.

PSEN1 GRIN2B

1.03e-052112224025330
Pubmed

Localization of heterotypic gap junctions composed of connexin45 and connexin36 in the rod pathway of the mouse retina.

GJD2 GJC1

1.03e-052112217004931
Pubmed

Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain.

GRIN2A GRIN2B

1.03e-052112236038077
Pubmed

Neuronal connexin-36 can functionally replace connexin-45 in mouse retina but not in the developing heart.

GJD2 GJC1

1.03e-052112220930146
Pubmed

Roles of NMDA receptor NR2A and NR2B subtypes for long-term depression in the anterior cingulate cortex.

GRIN2A GRIN2B

1.03e-052112216045501
Pubmed

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior.

GRIN2A GRIN2B

1.03e-052112223201971
Pubmed

Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition.

GRIN2A GRIN2B

1.03e-052112211719203
Pubmed

NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).

CTBP1 CTBP2

1.03e-052112233524397
Pubmed

Analysis of correlation between serum D-serine levels and functional promoter polymorphisms of GRIN2A and GRIN2B genes.

GRIN2A GRIN2B

1.03e-052112216266783
Pubmed

NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise.

GRIN2A GRIN2B

1.03e-052112227915379
Pubmed

Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance.

CTBP1 CTBP2

1.03e-052112220964627
Pubmed

Substrate specificity of the two mitochondrial ornithine carriers can be swapped by single mutation in substrate binding site.

SLC25A2 SLC25A15

1.03e-052112222262851
Pubmed

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.

GRIN2A GRIN2B

1.03e-052112227839871
Pubmed

Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer.

FAT3 LRP1B

1.03e-052112238696842
Pubmed

NADH/NAD+ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2.

CTBP1 CTBP2

1.03e-052112234997967
Pubmed

Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases.

GRIN2A GRIN2B

1.03e-052112222187052
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease in a sex-specific manner.

GRIN2A GRIN2B

1.03e-052112217569088
Pubmed

Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory.

GRIN2A GRIN2B

1.03e-052112232179753
Pubmed

Altered effects of ethanol in NR2A(DeltaC/DeltaC) mice expressing C-terminally truncated NR2A subunit of NMDA receptor.

GRIN2A GRIN2B

1.03e-052112211530236
Pubmed

Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.

PPP1CA PPP1CC

1.03e-05211229882500
Pubmed

Virally mediated knock-down of NR2 subunits ipsilateral to the deprived eye blocks ocular dominance plasticity.

GRIN2A GRIN2B

1.03e-052112216944113
Pubmed

A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3.

CTBP1 CTBP2

1.03e-05211229479502
Pubmed

The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.

SLC25A2 SLC25A15

1.03e-052112212807890
Pubmed

Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes.

GRIN2A GRIN2B

1.03e-052112218197970
Pubmed

Gap junction-mediated death of retinal neurons is connexin and insult specific: a potential target for neuroprotection.

GJD2 GJC1

1.03e-052112225100592
Pubmed

Deletion of connexin45 in mouse retinal neurons disrupts the rod/cone signaling pathway between AII amacrine and ON cone bipolar cells and leads to impaired visual transmission.

GJD2 GJC1

1.03e-052112215659592
Pubmed

Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure.

CTBP1 CTBP2

1.03e-052112210364211
Pubmed

CtBP, an unconventional transcriptional corepressor in development and oncogenesis.

CTBP1 CTBP2

1.03e-052112211864595
Pubmed

Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor.

GRIN2A GRIN2B

1.03e-05211229822733
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease.

GRIN2A GRIN2B

1.03e-052112215742215
Pubmed

Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells.

CTBP1 CTBP2

3.08e-053112226871283
Pubmed

Studies on the subtype selectivity of CP-101,606: evidence for two classes of NR2B-selective NMDA receptor antagonists.

GRIN2A GRIN2B

3.08e-053112211897110
Pubmed

Biochemical evidence for the co-association of three N-methyl-D-aspartate (NMDA) R2 subunits in recombinant NMDA receptors.

GRIN2A GRIN2B

3.08e-053112210480938
Pubmed

Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A down-regulation and motor deficits.

GRIN2A GRIN2B

3.08e-053112215519237
Pubmed

MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP.

CTBP1 CTBP2

3.08e-053112225728771
Pubmed

NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice.

GRIN2A GRIN2B

3.08e-053112230352630
Pubmed

Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology.

GRIN2A GRIN2B

3.08e-053112238836461
Pubmed

D4 dopamine receptors modulate NR2B NMDA receptors and LTP in stratum oriens of hippocampal CA1.

GRIN2A GRIN2B

3.08e-053112221955919
Pubmed

Differential use of myristoyl groups on neuronal calcium sensor proteins as a determinant of spatio-temporal aspects of Ca2+ signal transduction.

NCALD HPCA

3.08e-053112211836243
Pubmed

Expression of connexins 36, 43, and 45 during postnatal development of the mouse retina.

GJD2 GJC1

3.08e-053112217029293
Pubmed

Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening.

GRIN2A GRIN2B

3.08e-053112237000222
InteractionPLCL2 interactions

SSTR3 PPP1CA PPP1CC PLCL2

2.64e-06191064int:PLCL2
GeneFamilySolute carriers

SLC36A1 SLC39A2 SLC18B1 SLC22A17 SLC16A12 SLC3A1 SLC6A12 SLC16A2 SLC25A2 SLC25A15

1.17e-053958210752
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B

4.20e-0478221201
GeneFamilyProtein phosphatase catalytic subunits|EF-hand domain containing

PPP1CA PPP1CC

1.53e-0313822693
GeneFamilyATPase phospholipid transporting

ATP8B4 ATP9B

2.05e-03158221210
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCL2 PLA2G4F

3.30e-0319822832
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 FAT3 GRIN2B CSMD3 LRP1B TRDN TENM4 ZFHX4

2.22e-0818411282cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 FAT3 GRIN2B CSMD3 LRP1B TRDN TENM4 ZFHX4

2.22e-081841128ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 FAT3 GRIN2B CSMD3 LRP1B TRDN TENM4 ZFHX4

2.22e-0818411282b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 FAT3 GRIN2A GRIN2B HPCA TENM4 PLCL2 SVOP

3.49e-081951128ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 ROR1 LAMA4 GSN UBE2O TENM4 ENTPD2

2.42e-071691127849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 SLC16A12 SLC3A1 SLC6A12 TENM4 RHOBTB1 MOGAT3

4.30e-0718411279434731f651820b05335085582960f08fbf895de
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCALD HECW1 RALYL GRIN2A GRIN2B CSMD3 TENM4

7.05e-0719811278ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HECW1 FAT3 GRIN2B CSMD3 LRP1B ATP12A

3.47e-061621126bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNLIP GRIN2B CSMD3 LRP1B ADCY8 ZFHX4

5.40e-061751126887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 HECW1 SLC16A12 SLC6A12 RHOBTB1 MOGAT3

5.77e-0617711262f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

NCALD SLC18B1 EFNA4 CEP120 FARS2 CUZD1

6.56e-061811126b193f3606554adc55c5906219d114288bb1f978a
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

ATP8B4 HECW1 ROR1 SLC3A1 RHOBTB1 IL17RB

7.20e-061841126dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

SLC36A1 ATP8B4 HECW1 ROR1 RHOBTB1 IL17RB

7.90e-061871126acd305475f3609800af0d7bc68d83ef41228080b
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H6PD GSN HPCA SLC16A2 ENTPD2 C1QTNF7

8.91e-0619111266cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H6PD GSN HPCA SLC16A2 ENTPD2 C1QTNF7

8.91e-061911126850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H6PD GSN HPCA SLC16A2 ENTPD2 C1QTNF7

8.91e-0619111268b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL8A1 LAMA4 CSMD3 TENM4 ZFHX4 ENTPD2

9.46e-061931126549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 FAT3 GRIN2A GRIN2B TENM4 PLCL2

9.46e-061931126461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 FAT3 GRIN2A GRIN2B TENM4 PLCL2

9.46e-0619311260dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCALD HECW1 FAT3 RALYL GRIN2A HPCA

1.00e-051951126787e95fb59c40bba784544b662fac37606ae1427
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 FAT3 RALYL GRIN2A CSMD3 VPS13A

1.00e-0519511262e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL8A1 HECW1 LAMA4 F2RL2 GSN C1QTNF7

1.03e-051961126e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL8A1 HECW1 LAMA4 F2RL2 GSN C1QTNF7

1.03e-05196112682fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL8A1 HECW1 LAMA4 F2RL2 GSN C1QTNF7

1.03e-05196112685e5046f774537684e1443c0fc147d562b7068d0
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCALD ROR1 GSN TENM4 ZFHX4 ENTPD2

1.06e-0519711262744cc94883c5d0424677cf5093bbab622933e9b
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TDRD9 FAT3 ROR1 LAMA4 LRP1B SVOP

1.09e-051981126cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCellSigmoid-(1)_T_cell-(17)_gd_T|Sigmoid / shred on region, Cell_type, and subtype

NCALD ATP8B4 TRDV3 SLC25A15 PLCL2 ALOX5AP

1.16e-052001126a02e5a69f7101accd8f1394ab1c8007e211187f7
ToppCellSigmoid-T_cell-gd_T|Sigmoid / Region, Cell class and subclass

NCALD ATP8B4 TRDV3 SLC25A15 PLCL2 ALOX5AP

1.16e-052001126eef4df008cccdf6297b1c90c986c68793afd8b78
ToppCell(17)_gd_T|World / shred on Cell_type and subtype

NCALD ATP8B4 TRDV3 DOCK5 SLC25A15 ALOX5AP

1.19e-0520111267fcfe48758acf07cb3dda939ce589ae1518e41c9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MMP20 CSMD3 TG PLCL2 CERS4

2.43e-0513611257cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

HECW1 PMIS2 GRIN2A CSMD3 LRP1B

2.69e-051391125a1945b07f177cde40e7eea03a19236ce76165857
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 GRIN2B CSMD3 LRP1B ATP12A

3.30e-05145112596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK_CD56bright|Leuk-UTI / Disease, Lineage and Cell Type

ATP8B4 TMEM241 ROR1 GSN TENM4

4.82e-051571125db0057741d06e212a9543cb4b011659b79efeafc
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 GRIN2B LRP1B ADCY8 ZFHX4

5.27e-051601125c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 GRIN2B LRP1B ADCY8 ZFHX4

5.27e-05160112525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2C18 CYP4B1 GSN TG ATP12A

5.76e-05163112522fa5d017ff796394394d952ec151e2d1beb8248
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 GRIN2A F2RL2 HPCA SVOP

6.46e-0516711253dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 GRIN2A F2RL2 HPCA SVOP

6.46e-05167112595b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 GRIN2A F2RL2 HPCA SVOP

6.46e-0516711259480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC36A1 B4GALT1 SCNN1A PLA2G4F ATP12A

6.65e-05168112503896466698a79f7f1ad862cb7e05585260e2a5a
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCALD ATP8B4 CYB5RL CEP120 PLCL2

6.83e-0516911258caf7996796a2e2716e3855de855c903d6126bf2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 HECW1 RALYL SLC16A12 RHOBTB1

7.63e-0517311258888434641ea554a9b62c436e87920378eef29cd
ToppCellILEUM-inflamed-(1)_T_cell-(1)_T_(gd)|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ATP8B4 RALYL DOCK5 SLC25A15 CTBP2

7.63e-05173112562f2f42f54c9c6941bf888956be40230f92c883e
ToppCellfacs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMED6 FAXC TG RHOBTB1 CUZD1

7.84e-0517411253b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCellCF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

TG DOCK5 HPCAL1 VNN2 ALOX5AP

8.06e-0517511258020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT3 H6PD ADCY8 SCNN1A ATP12A

8.06e-051751125dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 LAMA4 GSN TENM4 ENTPD2

8.28e-051761125fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 LAMA4 GSN TENM4 ENTPD2

8.28e-051761125f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

ROR1 LRP1B SLC3A1 SCNN1A IL17RB

8.28e-05176112536f77d878a53b30465b0dea8333a3865dba75613
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

COL8A1 CYP4B1 ROR1 SCNN1A C1QTNF7

8.50e-0517711253128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIN2A CSMD3 PLCL2 SCNN1A CERS4

8.73e-05178112551d2188406f04329311b2efd1108fc36617a860e
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABO PNLIP GSN HPCAL1 SCNN1A

8.73e-05178112507d6d5275a4d17f8024fde74e92ab2505b4adfbf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH3 FAT3 GRIN2A C1QTNF7 CERS4

9.44e-051811125c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 HECW1 ADCY8 RHOBTB1 IL17RB

9.69e-051821125e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL8A1 NCALD GSN ZFHX4 C1QTNF7

9.69e-0518211253dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 HECW1 ADCY8 RHOBTB1 IL17RB

9.69e-05182112557bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 ROR1 DOCK5 TENM4 C1QTNF7

9.94e-0518311257eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

TG DOCK5 HPCAL1 VNN2 ALOX5AP

9.94e-051831125da43827952e6fdee2ce94648c316182f272b321c
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

SLC16A12 SLC3A1 RHOBTB1 VPS13A IL17RB

1.02e-04184112551ed1ebfdef45149541917c66cbacad87072e51f
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A12 SLC3A1 RHOBTB1 SLC16A2 SLC25A15

1.02e-041841125c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A12 SLC3A1 RHOBTB1 SLC16A2 SLC25A15

1.02e-0418411257c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL8A1 LAMA4 FAXC EFNA4 ENTPD2

1.05e-0418511251b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 ABO GSN CSRNP1 ATP12A

1.05e-041851125fd1911b57927c03470f9387962ca9581e5643fb3
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CYP4B1 GRIN2A GRIN2B SSTR3 ENTPD2

1.05e-041851125492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCellfacs-Large_Intestine-Distal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 ABO GSN CSRNP1 ATP12A

1.05e-0418511257a18d525de6f874924bfc61b9666b307da86421a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 SSTR3 SLC6A12 ZFHX4 MRPS6

1.05e-041851125a6874dd3030d04380cc3c01de1069461aad4ef45
ToppCellMild-NK|World / Disease group and Cell class

ATP8B4 ROR1 GSN RHOBTB1 CTBP2

1.05e-0418511250565b7c464e1a09e596f5a0b363d2dc9b55c3c50
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM241 HECW1 FAT3 RALYL VPS13A

1.07e-04186112584ba666237c18189d7e7556bd92dd953af733c00
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GRIN2B CSMD3 LRP1B TENM4 ROCK1

1.07e-04186112523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B4 HECW1 SLC6A12 RHOBTB1 MOGAT3

1.07e-041861125a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCALD ATP8B4 GSN DOCK5 VWA5A

1.07e-041861125855c2e5a8a6cf94c7de31982e0e2416f924439d3
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

NCALD SLC18B1 CEP120 FARS2 CUZD1

1.10e-041871125689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NCALD SLC18B1 CEP120 FARS2 CUZD1

1.10e-0418711254527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

ROR1 SLC3A1 RHOBTB1 VPS13A IL17RB

1.10e-041871125d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCelldroplet-Pancreas|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJD2 TMED6 PNLIP SSTR3 CUZD1

1.10e-0418711255f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

HECW1 FAT3 LAMA4 TENM4 C1QTNF7

1.10e-041871125bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

GRIN2A CSMD3 PLCL2 SCNN1A CERS4

1.10e-041871125ce05b89860573fe0356102e2998d1ef6d1968034
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 LAMA4 H6PD GSN C1QTNF7

1.10e-041871125976b74d081b7fba8620768613cc26f9262cd7b16
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CYP4B1 GRIN2A GRIN2B SSTR3 ENTPD2

1.13e-0418811259655a4c47b644a870017d349b99063e17dbae572
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL8A1 NCALD TRDV3 GSN CERS4

1.16e-041891125f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM241 HECW1 FAT3 RALYL VPS13A

1.16e-041891125a75226616340045b581d08429d2e123e041dee55
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B SLC16A12 TENM4 SCNN1A MRPS6

1.19e-0419011253dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM241 HECW1 FAT3 RALYL VPS13A

1.19e-04190112549e09cdb843b3d889a06a811aa5affae68b25a75
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 RALYL SLC16A12 SLC3A1 RHOBTB1

1.22e-0419111253c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 RALYL SLC16A12 SLC3A1 RHOBTB1

1.22e-0419111251c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJD2 PNLIP SSTR3 SLC22A17 SLC16A12

1.22e-041911125d48e5f67d384226add7d7fb2a124954136e09a82
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 NCALD ROR1 LAMA4 GRIN2A

1.22e-04191112539092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA4 H6PD GSN ENTPD2 C1QTNF7

1.22e-041911125997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 NCALD ROR1 LAMA4 GRIN2A

1.22e-041911125ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-TRGV4_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCALD ATP8B4 TRDV3 CSRNP1 ALOX5AP

1.25e-041921125f4b5a55a648e366234079411b6fdd2da75a4740e
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 LAMA4 GSN ENTPD2 C1QTNF7

1.25e-041921125671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 NCALD LAMA4 GRIN2A ZFHX4

1.25e-0419211255105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 NCALD LAMA4 GRIN2A ZFHX4

1.25e-041921125d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL8A1 HECW1 LAMA4 TENM4 ZFHX4

1.25e-04192112567e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HECW1 RALYL GRIN2A GRIN2B SVOP

1.25e-0419211254c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL8A1 LAMA4 TRDN ADCY8 C1QTNF7

1.25e-0419211252cc712186e37fb21a964c032765c36a8b4a852cf
ToppCellfacs-Lung-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA4 H6PD GSN ENTPD2 C1QTNF7

1.25e-0419211258df15085b35b86f39debd933284cb703c5dd63c2
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 LAMA4 GSN ENTPD2 C1QTNF7

1.25e-041921125840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM241 HECW1 FAT3 RALYL VPS13A

1.25e-0419211255c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 ABO GSN CSRNP1 ANO7

1.28e-0419311254aee372ba2c0351b0221d0d468707d1ad21526d6
ComputationalCytochrome P450.

CYP2C8 CYP2C18 CYP4B1

9.15e-0514703MODULE_106
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A

COL8A1 HECW1 CYP4B1 GSN SLC3A1 CUZD1 CTSO CERS4

5.21e-0619511183844_UP
Drugbutanol

ABO PNLIP PSEN1 GRIN2A GRIN2B ADCY8 TG

6.26e-061421117CID000000263
Diseaseornithine translocase deficiency (implicated_via_orthology)

SLC25A2 SLC25A15

1.33e-0521082DOID:0050720 (implicated_via_orthology)
DiseaseMood Disorders

ABO DBH GRIN2A SSTR3 ADCY8 VPS13A

3.69e-051681086C0525045
DiseaseDepressive disorder

PSEN1 SRD5A1 DBH GRIN2A GRIN2B ADCY8 TG

9.64e-052891087C0011581
Diseasebeta-1,4-galactosyltransferase 1 measurement

ABO B4GALT1

1.32e-0451082EFO_0801409
Diseasemacrophage colony-stimulating factor 1 receptor measurement

ABO B4GALT1

1.97e-0461082EFO_0020547
DiseaseMental Depression

PSEN1 SRD5A1 DBH GRIN2A GRIN2B ADCY8

3.53e-042541086C0011570
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B

3.66e-0481082DOID:3891 (biomarker_via_orthology)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B

3.66e-0481082DOID:1561 (biomarker_via_orthology)
Diseaseneuroblastoma (is_marker_for)

SCNN1A ALOX5AP

3.66e-0481082DOID:769 (is_marker_for)
Diseasesemaphorin-3G measurement

ABO MOGAT3

3.66e-0481082EFO_0802049
DiseaseInherited neuropathies

ATP7A SPG11 WASHC5

4.27e-04401083C0598589
Diseaset-cell surface glycoprotein CD5 measurement

ABO B4GALT1

4.70e-0491082EFO_0803134
DiseaseIgG fucosylation measurement

B4GALT1 MOGAT3

5.86e-04101082EFO_0008427
DiseaseAmyloidosis

PSEN1 GSN

5.86e-04101082C0002726
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A GRIN2B

7.14e-04111082DOID:9279 (implicated_via_orthology)
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

7.14e-04111082DOID:8725 (is_marker_for)
Diseasecampesterol measurement

ABO SLC3A1

7.14e-04111082EFO_0020008
DiseaseIgG galactosylation measurement

B4GALT1 MOGAT3

8.55e-04121082EFO_0008425
Diseaseecosanoids measurement

CYP2C8 CYP2C18 CYP4B1

1.09e-03551083EFO_0020044
Diseaseoptic cup area measurement

COL8A1 ABO FAT3

1.15e-03561083EFO_0006940
Diseaserefractive error

GJD2 TDRD9 GRIN2A GRIN2B CTBP2 CERS4

1.29e-033261086MONDO_0004892
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ABO SPG11 PIK3R2

1.47e-03611083EFO_0008317, EFO_0008596, EFO_0020946
Diseasealcohol use disorder (is_implicated_in)

DBH GRIN2B

1.54e-03161082DOID:1574 (is_implicated_in)
Diseaserespiratory symptom change measurement, response to placebo

ADCY8 FARS2

1.74e-03171082EFO_0008344, EFO_0010068
Diseasealpha-L-iduronidase measurement

NKX1-1 CTBP1

1.74e-03171082EFO_0020139
Diseasefacial asymmetry measurement

ROR1 KCMF1

2.18e-03191082EFO_0009751
DiseaseJoubert syndrome 1

CEP120 TCTN2

2.66e-03211082C4551568
Diseasegastric ulcer

ABO PLCL2

2.66e-03211082EFO_0009454
DiseaseNephritis, Tubulointerstitial

SLC16A12 SLC3A1

2.66e-03211082C0041349
DiseaseN-glycan measurement

B4GALT1 MOGAT3

2.92e-03221082EFO_0004999
Diseaseepilepsy (implicated_via_orthology)

GRIN2A GRIN2B LRP1B ATP12A

3.08e-031631084DOID:1826 (implicated_via_orthology)
DiseaseAlcoholic Intoxication, Chronic

ABO SRD5A1 DBH GRIN2A GRIN2B

3.10e-032681085C0001973
DiseaseHuntington's disease (is_implicated_in)

GRIN2A GRIN2B

3.19e-03231082DOID:12858 (is_implicated_in)
DiseaseNephritis, Interstitial

SLC16A12 SLC3A1

3.48e-03241082C0027707

Protein segments in the cluster

PeptideGeneStartEntry
SVAGIFNYYLIFFFG

ALOX5AP

126

P20292
FFLNGGYSYRGVIFP

ADCY8

141

P40145
FGFSLPYVQYFGGVS

B4GALT1

276

P15291
GFHYFYGVPFGLLSD

ARSH

136

Q5FYA8
PNNAYYFIGFLGDEL

ATG4A

261

Q8WYN0
ESISNRGPFFGYYFF

CERS4

291

Q9HA82
IPKDEGDFYYLGGFF

ABO

256

P16442
GQYFLYGFSVPGLYE

GJD2

216

Q9UKL4
GTVVFYDCNPGYFLF

CSMD3

2956

Q7Z407
YDCNPGYFLFGSSVL

CSMD3

2961

Q7Z407
FGFNVLFYDPYLSDG

CTBP1

196

Q13363
AFGFSVIFYDPYLQD

CTBP2

201

P56545
NFSKVYGPVFTVYFG

CYP2C8

56

P10632
SLVLFFIPYGAFYNV

ATP8B4

966

Q8TF62
FIPYGAFYNVAGEDG

ATP8B4

971

Q8TF62
FLNFEIVETYFPGYN

ATP7A

961

Q04656
FGIAAAALGYFVPYV

SLC16A2

326

P36021
EPFLSVGGYVFDYDY

RALYL

116

Q86SE5
IYANFFPYGDASKFA

HPCA

51

P84074
IAFFKGRFVGYPGNY

ANO7

606

Q6IWH7
FSFYGDIIAFPLQDY

FAXC

36

Q5TGI0
FPYVYGFSDGLFQAI

OR5M11

146

Q96RB7
TDILGFIYPFNYSGD

LRP1B

3896

Q9NZR2
YYTDSIVNPDGFAGF

PNLIP

286

P16233
FDGITVFYFPRCQGF

CSRNP1

86

Q96S65
ELFNPYYGLFEYSAN

HECW1

1306

Q76N89
FLVYFTVYAQEGFLP

ATP12A

881

P54707
SVFYFASVPLYQGFL

ATP9B

951

O43861
FSYIGFPVELNTVYF

IL17RB

121

Q9NRM6
PPVAGNFVAFSAFFY

ENTPD2

336

Q9Y5L3
YVPALFSVFAYRFGG

OR52B6

271

Q8NGF0
TFAFPYFEGSFQPFI

DBX1

136

A6NMT0
GFEFLPGETYYYISV

EFNA4

121

P52798
KYAGESFPGIYDALF

FOLH1B

391

Q9HBA9
IYANFFPYGDASKFA

HPCAL1

51

P37235
FGDFFYKPNQYGELL

CYB5RL

171

Q6IPT4
VPSLLEVAGFSYFYG

LPCAT3

181

Q6P1A2
FLGFGSYFCYDNPAA

MFSD1

51

Q9H3U5
YYVAVFPFIGLGKVF

MFSD1

276

Q9H3U5
YGAYVPTELFGSELF

PLA2G4F

526

Q68DD2
GSYGNFIVFLSFFDP

GPR75

56

O95800
AYQYVLTFLFMGPFF

MOGAT3

26

Q86VF5
ALLFYGTTVGVYFFP

OR1S2

261

Q8NGQ3
SPFQLYYFISLAFFG

F2RL2

256

O00254
VYFCERPGSFYGTLF

FANCB

691

Q8NB91
FEYGGFPPESNYLFL

PPP1CA

76

P62136
DYSLKLFFENPYNGG

PARP14

241

Q460N5
YRTATGFGFAEPYNL

PIK3R2

671

O00459
FGDEYDFYRSFPGFQ

EXOSC10

56

Q01780
EYFAVGYYGQGFPSF

DOCK5

1361

Q9H7D0
NPKFSFLFGGEFYSY

CHERP

41

Q8IWX8
NNIFPERGSIYDFYF

DNAH3

2001

Q8TD57
QPEFFFYYSLLGNDV

CEP120

216

Q8N960
FLIGQYFLYGFQVHP

GJC1

191

P36383
AKAFYYPEEAGLAFG

DBH

306

P09172
GFLDFYSINRQGPYF

FAT3

711

Q8TDW7
GKNFYYGSAFLVIPA

CALHM4

46

Q5JW98
GIFTCEVPGVYYFAY

COL8A1

651

P27658
FDLYYGGEAFSVEQP

KCMF1

61

Q9P0J7
NFSKVYGPVFTVYFG

CYP2C18

56

P33260
GQFIGFLNIYEPDYA

CYP4B1

86

P13584
VPTNLYGDFFTGDAY

GSN

81

P06396
YPLFGHYGRFQFNAF

CUZD1

471

Q86UP6
AGRIFYFSVPPFAYE

H6PD

136

O95479
QFGLLFGEYFSYPVS

SCNN1A

101

P37088
IYGNFFPYGDASKFA

NCALD

51

P61601
ATGKFICAFPGIYYF

C1QTNF7

181

Q9BXJ2
YLHVFYDFGFSGGPV

LAMA4

1106

Q16363
AVELNGYIYFFSGPK

MMP20

446

O60882
FISGGFQAAYVYTPE

SVOP

436

Q8N4V2
AFQGYYLPNDDGEFY

TAX1BP1

86

Q86VP1
GGYFLVDFYAPTAAV

MRPS6

61

P82932
FGLVFYFATDYLVQP

PSEN1

441

P49768
FFGLYFLVVALPYAN

SSTR3

291

P32745
FASGYLFLGYPADRF

SLC22A17

111

Q8WUG5
QVVLAGAFYPNYFTF

TDRD9

741

Q8NDG6
GFLYQSFGYEVPFIV

SLC18B1

186

Q6NT16
FAFASLYTQIPGLYG

LMF2

21

Q9BU23
FVLGSQTYGAPAFYA

NKX1-1

431

Q15270
LVPFSCTFGYFDGAY

SLC16A12

376

Q6ZSM3
VYAFYEAVAGFVAPV

GPR150

231

Q8NGU9
YIGDEFIGQYTIPFE

PLCL2

836

Q9UPR0
CYKNGGGAFFIPYFI

SLC6A12

66

P48065
YYGLPFIQEADFPFN

SLC3A1

396

Q07837
LGLPYYETSVFDQFG

RHOBTB1

181

O94844
FPPFGLAALYFSYEG

PMIS2

81

A0A1W2PS18
VPGYFFFFGGYELSR

SLC25A15

181

Q9Y619
TLLQEVPGYFFFFGG

SLC25A2

176

Q9BXI2
VPGYFFFFGGYELSR

SLC25A2

181

Q9BXI2
EYPYGELIISLGFFF

SLC39A2

101

Q9NP94
FYGINQFSYLFPEEF

CTSO

66

P43234
GGVLFSLEEVSYYFP

CLCN3

331

P51790
FSFGLQPYYGFSNQE

ROR1

686

Q01973
YYLHNGRPSFAFGTF

SPG11

1201

Q96JI7
FGIFTCFDIFFYDPG

VNN2

206

O95498
GQFLPYFIPGFASYF

ZFHX4

3211

Q86UP3
YGDIIFDFSYFKGPE

WASHC5

51

Q12768
FSEGVEAFFYEPYQG

VPS13A

2876

Q96RL7
IGIFFTYALQFYVPA

SLC36A1

341

Q7Z2H8
FNAFVLDKTYFGPYD

PWP2

131

Q15269
FYFAIPVGSGLGYIA

SPNS1

191

Q9H2V7
GLFFDDSYGFYPGQV

UBE2O

251

Q9C0C9
QVYLNFGVFYEGPET

TMED6

131

Q8WW62
GYDGFFVISVEQYPE

TENM4

2736

Q6N022
FNIYGFGSSYEACFP

VWA5A

326

O00534
FEYGGFPPESNYLFL

PPP1CC

76

P36873
AFVGNQLPFVGFTYY

ROCK1

386

Q13464
IRPDYSFQFVFYGDN

TRDV3

56

A0JD37
GDLFSVLDFPFLYFY

TMEM241

201

Q24JQ0
CVYLDGYNGYGFQFP

TRDN

691

Q13061
PRGGLFEYVTAANYF

SRD5A1

186

P18405
YVGRFGTPLFSVYDN

FARS2

101

O95363
ALGLPFYPAYEGQFS

TG

2631

P01266
LANTPFLGYFYHGAV

TCTN2

241

Q96GX1
IAVFVFEYFSPVGYN

GRIN2A

571

Q12879
AVAVFVFEYFSPVGY

GRIN2B

571

Q13224