Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpolyol transmembrane transporter activity

AQP9 SLC5A3

5.29e-0513172GO:0015166
GeneOntologyMolecularFunctionWnt-protein binding

FZD5 SFRP1

3.77e-0434172GO:0017147
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

AQP9 SLC5A3

5.76e-0442172GO:0015144
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

AQP9 SLC5A3

1.59e-0370172GO:1901618
GeneOntologyMolecularFunctionsymporter activity

SLC6A17 SLC5A3

7.08e-03150172GO:0015293
GeneOntologyBiologicalProcesspolyol transmembrane transport

AQP9 SLC5A3

3.71e-0512162GO:0015791
GeneOntologyBiologicalProcessendoplasmic reticulum membrane organization

REEP5 LPCAT3

4.38e-0513162GO:0090158
DomainFrizzled/SFRP

FZD5 SFRP1

9.29e-0516172IPR015526
DomainFRI

FZD5 SFRP1

1.47e-0420172SM00063
Domain-

FZD5 SFRP1

1.62e-04211721.10.2000.10
DomainFrizzled_dom

FZD5 SFRP1

2.13e-0424172IPR020067
DomainFZ

FZD5 SFRP1

2.13e-0424172PS50038
DomainFz

FZD5 SFRP1

2.13e-0424172PF01392
DomainPH

DOCK10 PLEKHG5

2.59e-02278172SM00233
DomainPH_DOMAIN

DOCK10 PLEKHG5

2.61e-02279172PS50003
DomainPH_domain

DOCK10 PLEKHG5

2.63e-02280172IPR001849
Pubmed

Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling.

FZD5 SFRP1

6.74e-07317224080158
Pubmed

Expression profile of WNT molecules in prostate cancer and its regulation by aminobisphosphonates.

FZD5 SFRP1

2.25e-06517221344486
Pubmed

Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon.

FZD5 SFRP1

4.72e-06717211335128
Pubmed

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.

FZD5 SFRP1

4.72e-0671729192640
Pubmed

Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate.

FZD5 SFRP1

3.83e-051917220890044
Pubmed

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

FZD5 SFRP1

6.17e-05241729096311
Pubmed

A role for Wnt/beta-catenin signaling in lens epithelial differentiation.

FZD5 SFRP1

6.70e-052517212812787
Pubmed

Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus.

FZD5 SFRP1

1.11e-043217220308569
Pubmed

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

FZD5 SFRP1

1.40e-043617212412008
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

FZD5 SFRP1

1.48e-043717235831952
Pubmed

Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.

FZD5 SFRP1

1.56e-043817221041481
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

FZD5 SFRP1

2.61e-044917219562671
Pubmed

Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation.

FZD5 SFRP1

3.79e-045917226450967
GeneFamilySolute carriers

SLC25A27 SLC6A17 SLC5A3

2.51e-03395133752
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK10 PLEKHG5

9.28e-03206132682
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG5 SLC5A3 ZNF44

2.68e-0515617314e2f693a75f1075f40cc7b16ee430262a5de016
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A17 SFRP1 SLC5A3

4.83e-051901735cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A17 SFRP1 SLC5A3

4.83e-05190173c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A17 SFRP1 SLC5A3

4.90e-05191173e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A17 SFRP1 SLC5A3

4.90e-05191173297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A17 SFRP1 SLC5A3

4.98e-0519217361c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

FZD5 SFRP1 SLC5A3

4.98e-051921737a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A17 SFRP1 SLC5A3

4.98e-05192173e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|World / Stress and Cell class

FZD5 SFRP1 SLC5A3

5.06e-05193173f31398dad5321a7bcb27e208bd73630e9756e897
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A17 SFRP1 SLC5A3

5.21e-0519517360d08fb27469d1e247bc47b651d7023ba82cf92f
ToppCell(2)_5-FU|World / Stress and Cell class

FZD5 SFRP1 SLC5A3

5.21e-05195173e5b1d96fafeb2f3b1f4cdf6b2c9eddef36bca7ff
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|(2)_5-FU / Stress and Cell class

FZD5 SFRP1 SLC5A3

5.29e-05196173cc0a172de71d9a1a882c9e78652dae70e007d012
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-37|World / Primary Cells by Cluster

REEP5 SLC6A17 TSPAN7

5.37e-0519717300d756bc0231e1b3b88430214338c1059cb11106
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

FZD5 SFRP1 SLC5A3

5.37e-05197173434ae0231972acba12d06279908cf407e70511ac
DiseaseHbA1c measurement

LPCAT3 DPY19L3 SFRP1

6.38e-03675173EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
MCLFGRMKWFKLPFY

AQP9

91

O43315
ILLYLCYKFWPGMMD

DPY19L3

531

Q6ZPD9
TPFKWFMEMCVRGYL

PI4KA

2011

P42356
FWFRCMYMLIWGKFV

LPCAT3

266

Q6P1A2
FFMTPKFYVFMWLLA

GDPD4

461

Q6W3E5
AKPEYWVLMLKYFMC

FZD5

496

Q13467
FCSKLGKYRMPFAWA

DOCK10

546

Q96BY6
MSVFPVVMYFWKRFC

RGSL1

966

A5PLK6
YFILVMCIGFFAMWK

SLC5A3

16

P53794
PFYYMLKCGFLLWCM

REEP5

111

Q00765
FFGFYWPEMLKCDKF

SFRP1

146

Q8N474
KMFGSLFKPYIRYCM

PLEKHG5

426

O94827
FMSLYKGFLPSWLRM

SLC25A27

286

O95847
FFYPWFRKALKMMLF

TAAR1

306

Q96RJ0
RFYFYMWKFVSPLCM

SLC6A17

566

Q9H1V8
CRGSPWMLKLYAMFL

TSPAN7

81

P41732
MALCYGTFWGYPKML

ZNF44

1

P15621