Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin filament binding

MYH10 ABL2 MYO1E MYO7B GAS7 VPS16 SVIL MACF1 PLEC

2.45e-052271359GO:0051015
GeneOntologyMolecularFunctionactin binding

MYH10 ABL2 MYO1E MYO7B COBLL1 LRRK2 GAS7 VPS16 SVIL ENAH MACF1 PLEC

1.02e-0447913512GO:0003779
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH10 DNAH10 MYO1E MYO7B DNAH9 DNAH11

1.51e-041181356GO:0003774
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

KALRN SLC38A9 DOCK10 ARFGEF2 ARHGEF10L RIN2 ARHGEF9 RIC1

1.78e-042311358GO:0005085
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH9 DNAH11

2.29e-04181353GO:0008569
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

CCT3 DNAH10 KRT35 ARFGEF2 GAS7 HAUS3 VPS16 RADIL SVIL CDK5RAP2 MACF1 PLEC DNAH9 KRT36 MX1 CSTPP1 DNAH11

6.33e-0589913417GO:0099513
GeneOntologyCellularComponentmicrotubule

CCT3 DNAH10 ARFGEF2 HAUS3 RADIL SVIL CDK5RAP2 MACF1 DNAH9 MX1 CSTPP1 DNAH11

1.68e-0453313412GO:0005874
GeneOntologyCellularComponentsupramolecular fiber

MYH10 CCT3 DNAH10 KRT35 ARFGEF2 GAS7 HAUS3 VPS16 RYR3 RADIL SVIL CDK5RAP2 MACF1 PLEC DNAH9 KRT36 MX1 CSTPP1 DNAH11

1.89e-04117913419GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

MYH10 CCT3 DNAH10 KRT35 ARFGEF2 GAS7 HAUS3 VPS16 RYR3 RADIL SVIL CDK5RAP2 MACF1 PLEC DNAH9 KRT36 MX1 CSTPP1 DNAH11

2.06e-04118713419GO:0099081
GeneOntologyCellularComponentdynein complex

DNAH10 DYNC2I1 DNAH9 DNAH11

3.98e-04541344GO:0030286
MousePhenodecreased effector memory CD4-positive, alpha-beta T cell number

PTPRC NEK8 PRKDC

4.49e-05101033MP:0010845
MousePhenoimpaired coordination

VIPR1 MYH10 ANKFY1 ABL2 KALRN CCR9 NPAS3 GAS7 ITPR1 RAB18 VPS35 CHD6 MUSK

4.80e-0547810313MP:0001405
DomainDHC_N1

DNAH10 DNAH9 DNAH11

1.84e-0581313PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH9 DNAH11

1.84e-0581313IPR013594
DomainARM-type_fold

LRRK2 ARFGEF2 RYR3 ITPR1 FOCAD PIK3CB PI4KA VPS35 MROH7 PRKDC UNC79

2.73e-0533913111IPR016024
DomainSPEC

AKAP6 KALRN MACF1 PLEC

7.14e-05321314SM00150
DomainSpectrin/alpha-actinin

AKAP6 KALRN MACF1 PLEC

7.14e-05321314IPR018159
DomainKinase-like_dom

ABL2 BMP2K KALRN LRRK2 TEX14 STK32A PTK2B PIK3CB PI4KA NEK8 MACF1 PRKDC MUSK

1.15e-0454213113IPR011009
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH9 DNAH11

1.16e-04141313IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH9 DNAH11

1.16e-04141313IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH9 DNAH11

1.16e-04141313IPR013602
DomainDHC_N2

DNAH10 DNAH9 DNAH11

1.16e-04141313PF08393
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH9 DNAH11

1.16e-04141313IPR011704
DomainMT

DNAH10 DNAH9 DNAH11

1.16e-04141313PF12777
DomainAAA_8

DNAH10 DNAH9 DNAH11

1.16e-04141313PF12780
DomainAAA_5

DNAH10 DNAH9 DNAH11

1.16e-04141313PF07728
DomainDHC_fam

DNAH10 DNAH9 DNAH11

1.44e-04151313IPR026983
DomainDynein_heavy

DNAH10 DNAH9 DNAH11

1.44e-04151313PF03028
DomainPI3/4_kinase_CS

PIK3CB PI4KA PRKDC

1.44e-04151313IPR018936
DomainDynein_heavy_dom

DNAH10 DNAH9 DNAH11

1.44e-04151313IPR004273
Domain-

PIK3CB PI4KA PRKDC

1.77e-041613131.10.1070.11
DomainPI3Kc

PIK3CB PI4KA PRKDC

1.77e-04161313SM00146
DomainPI3_PI4_kinase

PIK3CB PI4KA PRKDC

2.55e-04181313PF00454
DomainPI3_4_KINASE_1

PIK3CB PI4KA PRKDC

2.55e-04181313PS00915
DomainPI3_4_KINASE_2

PIK3CB PI4KA PRKDC

2.55e-04181313PS00916
DomainPI3/4_kinase_cat_dom

PIK3CB PI4KA PRKDC

2.55e-04181313IPR000403
DomainPI3_4_KINASE_3

PIK3CB PI4KA PRKDC

2.55e-04181313PS50290
DomainBRK

CHD8 CHD6

7.19e-0461312SM00592
DomainRIH_assoc-dom

RYR3 ITPR1

7.19e-0461312IPR013662
Domain-

MACF1 PLEC

7.19e-04613123.90.1290.10
DomainBRK_domain

CHD8 CHD6

7.19e-0461312IPR006576
DomainIns145_P3_rec

RYR3 ITPR1

7.19e-0461312PF08709
DomainRIH_assoc

RYR3 ITPR1

7.19e-0461312PF08454
DomainRIH_dom

RYR3 ITPR1

7.19e-0461312IPR000699
DomainIns145_P3_rcpt

RYR3 ITPR1

7.19e-0461312IPR014821
DomainRyanodine_recept-rel

RYR3 ITPR1

7.19e-0461312IPR015925
Domain-

RYR3 ITPR1

7.19e-04613121.25.10.30
DomainRYDR_ITPR

RYR3 ITPR1

7.19e-0461312PF01365
DomainBRK

CHD8 CHD6

7.19e-0461312PF07533
DomainSH3

ABL2 MYO1E KALRN MYO7B GAS7 ARHGEF9 MACF1

8.35e-042161317PS50002
DomainSH3_domain

ABL2 MYO1E KALRN MYO7B GAS7 ARHGEF9 MACF1

9.29e-042201317IPR001452
DomainPlectin

MACF1 PLEC

1.00e-0371312PF00681
DomainPlectin_repeat

MACF1 PLEC

1.00e-0371312IPR001101
DomainPLEC

MACF1 PLEC

1.00e-0371312SM00250
DomainSpectrin_repeat

KALRN MACF1 PLEC

1.08e-03291313IPR002017
DomainCyclin_L/T

CCNL2 CCNL1

1.33e-0381312IPR015429
DomainPI3Ka

PIK3CB PI4KA

1.70e-0391312PF00613
DomainPI3Ka

PIK3CB PI4KA

1.70e-0391312SM00145
Domain-

PIK3CB PI4KA

1.70e-03913121.25.40.70
DomainUbiquitin-rel_dom

MYO7B FRMD1 PTK2B RADIL PIK3CB RIN2

1.91e-031841316IPR029071
DomainMIR

RYR3 ITPR1

2.12e-03101312PF02815
DomainMIR_motif

RYR3 ITPR1

2.12e-03101312IPR016093
DomainPI_Kinase

PIK3CB PI4KA

2.12e-03101312IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3CB PI4KA

2.12e-03101312IPR001263
DomainMIR

RYR3 ITPR1

2.12e-03101312PS50919
DomainMIR

RYR3 ITPR1

2.12e-03101312SM00472
DomainPIK_HELICAL

PIK3CB PI4KA

2.12e-03101312PS51545
DomainMyosin_head_motor_dom

MYH10 MYO1E MYO7B

2.38e-03381313IPR001609
DomainMYOSIN_MOTOR

MYH10 MYO1E MYO7B

2.38e-03381313PS51456
DomainMyosin_head

MYH10 MYO1E MYO7B

2.38e-03381313PF00063
DomainMYSc

MYH10 MYO1E MYO7B

2.38e-03381313SM00242
DomainSer-Thr/Tyr_kinase_cat_dom

ABL2 TEX14 PTK2B NEK8 MUSK

2.90e-031381315IPR001245
DomainPH_dom-like

KALRN MYO7B DOCK10 FRMD1 ARHGEF10L PTK2B ENAH ARHGEF9 ACAP2

3.14e-034261319IPR011993
DomainKRAB

ZNF586 ZFP57 ZNF557 ZNF792 ZNF587 ZNF641 ZNF558 ZNF417

3.78e-033581318PS50805
DomainKRAB

ZNF586 ZFP57 ZNF557 ZNF792 ZNF587 ZNF641 ZNF558 ZNF417

3.78e-033581318PF01352
DomainFERM_M

MYO7B FRMD1 PTK2B

4.11e-03461313PF00373
DomainSH3

ABL2 MYO1E KALRN MYO7B GAS7 ARHGEF9

4.21e-032161316SM00326
DomainKRAB

ZNF586 ZFP57 ZNF557 ZNF792 ZNF587 ZNF641 ZNF558 ZNF417

4.53e-033691318SM00349
DomainKRAB

ZNF586 ZFP57 ZNF557 ZNF792 ZNF587 ZNF641 ZNF558 ZNF417

4.61e-033701318IPR001909
Domain-

MYO7B FRMD1 PTK2B

4.91e-034913131.20.80.10
DomainFERM_central

MYO7B FRMD1 PTK2B

4.91e-03491313IPR019748
DomainFERM_domain

MYO7B FRMD1 PTK2B

4.91e-03491313IPR000299
DomainFERM/acyl-CoA-bd_prot_3-hlx

MYO7B FRMD1 PTK2B

5.20e-03501313IPR014352
DomainFERM_1

MYO7B FRMD1 PTK2B

5.20e-03501313PS00660
DomainFERM_2

MYO7B FRMD1 PTK2B

5.20e-03501313PS00661
DomainFERM_3

MYO7B FRMD1 PTK2B

5.20e-03501313PS50057
DomainBand_41_domain

MYO7B FRMD1 PTK2B

5.20e-03501313IPR019749
DomainB41

MYO7B FRMD1 PTK2B

5.20e-03501313SM00295
DomainCyclin_C-dom

CCNL2 CCNL1

6.20e-03171312IPR004367
DomainCyclin_C

CCNL2 CCNL1

6.20e-03171312PF02984
DomainCyclin_C

CCNL2 CCNL1

6.20e-03171312SM01332
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

AKAP6 PRUNE2 ANKFY1 DOCK10 CHD8 BIRC6 UBR5 MACF1 CHD6 KLHL8

2.36e-082251371012168954
Pubmed

A human MAP kinase interactome.

MYH10 ABL2 CCT3 COBLL1 GAS7 CHD8 EXTL3 ARHGEF9 MACF1 CHD6 PRKDC PLEC PIBF1

7.33e-084861371320936779
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYH10 ANKFY1 NAA15 NUP107 CCT3 GNE DOCK10 CHD8 VPS16 BIRC6 TOE1 NUP205 UBR5 PI4KA VPS35 MACF1 PRKDC PLEC RPL5 PCID2

3.74e-0713531372029467282
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYH10 NUP107 CCT3 ARFGEF2 PI4KA MROH7 PRKDC PLEC

1.48e-06202137833005030
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYO1E KALRN HECTD4 ARFGEF2 CHD8 EXTL3 BIRC6 C8orf58 ARHGEF10L FOCAD RADIL PI4KA NEK8 PRKDC PLEC RIC1 BAHCC1

1.78e-0611051371735748872
Pubmed

A cohesin-RAD21 interactome.

CUL4A AMPD3 NAA15 CCT3 FOCAD UBE2O PRKDC RPL5

1.85e-06208137822145905
Pubmed

Biological, clinical and population relevance of 95 loci for blood lipids.

AMPD3 COBLL1 GPAM MACF1 PLEC KLHL8 DNAH11

1.94e-06146137720686565
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYH10 NAA15 NUP107 CCT3 CHD8 BIRC6 NUP205 UBE2O UBR5 MACF1 PRKDC PLEC RPL5

2.04e-066531371322586326
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

CUL4A ITGA11 MYH10 CCT3 KRT35 CCR9 ARFGEF2 NUP205 PI4KA NEK8 PRKDC PLEC

2.61e-065641371221565611
Pubmed

Functional proteomics mapping of a human signaling pathway.

MYH10 OTUB1 ARFGEF2 RFX1 ZNF557 PTPRC UBR5 ZNF587 VPS35 MACF1 CHD6 PLEC

4.20e-065911371215231748
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

MYH10 NUP107 CCT3 MYO1E GNE OTUB1 VPS16 VPS35 MACF1 PRKDC PLEC RPL5

4.98e-066011371233658012
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MXRA5 CCT3 GPAM PIWIL2 BIRC6 NUP205 FOCAD TMCO4 PI4KA PKHD1 SNX31 CHD6 PRKDC

7.42e-067361371329676528
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

MYH10 ABL2 BMP2K JADE3 DYNC2I1 HAUS3 CCDC77 NUP205 UBR5 SVIL ENAH PLEC PIBF1 PCID2

7.49e-068531371428718761
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

ANKFY1 NAA15 NUP107 GNE CHD8 BIRC6 NUP205 UBR5 VPS35 PRKDC RPL5

9.37e-065341371135032548
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

MYH10 ABL2 CCT3 BMP2K KRT35 PIK3CB PRKDC KRT36

1.13e-05266137819380743
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

MYH10 CCT3 MYO1E BMP2K POR NUP205 PRKDC PLEC

1.19e-05268137833024031
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 MYO1E KALRN HECTD4 ARFGEF2 DYNC2I1 GAS7 EXTL3 RYR3 FOCAD UBE2O ZNF558 CCDC15 MACF1 CHD6 PRKDC PLEC

1.29e-0512851371735914814
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

UBR5 ENAH MACF1 PRKDC PLEC

1.30e-0576137527542412
Pubmed

The role and molecular mechanism of metabolic reprogramming of colorectal cancer by UBR5 through PYK2 regulation of OXPHOS expression study.

PTK2B UBR5

1.54e-052137237098808
Pubmed

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.

AKAP6 ARHGEF10L

1.54e-052137229979793
Pubmed

Stromal Integrin α11β1 Affects RM11 Prostate and 4T1 Breast Xenograft Tumors Differently.

ITGA11 PRKDC

1.54e-052137226990302
Pubmed

CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis.

CUL4A PCID2

1.54e-052137219481525
Pubmed

CUL-4A is critical for early embryonic development.

CUL4A PCID2

1.54e-052137212077329
Pubmed

Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle.

CUL4A PCID2

1.54e-052137212393421
Pubmed

Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis.

CUL4A PCID2

1.54e-052137218339895
Pubmed

Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.

LRRK2 VPS35

1.54e-052137232631998
Pubmed

Cul4A is required for hematopoietic stem-cell engraftment and self-renewal.

CUL4A PCID2

1.54e-052137217616641
Pubmed

Complement Factor H-Related Proteins FHR1 and FHR5 Interact With Extracellular Matrix Ligands, Reduce Factor H Regulatory Activity and Enhance Complement Activation.

CFHR1 CFHR5

1.54e-052137235392081
Pubmed

VPS35 and retromer dysfunction in Parkinson's disease.

LRRK2 VPS35

1.54e-052137238368930
Pubmed

Circulating complement factor H-related proteins 1 and 5 correlate with disease activity in IgA nephropathy.

CFHR1 CFHR5

1.54e-052137228673452
Pubmed

Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.

PKHD1 PRKDC

1.54e-052137224984783
Pubmed

A novel CFHR1-CFHR5 hybrid leads to a familial dominant C3 glomerulopathy.

CFHR1 CFHR5

1.54e-052137228729035
Pubmed

What lysosomes actually tell us about Parkinson's disease?

LRRK2 VPS35

1.54e-052137226947123
Pubmed

Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells.

PTPRC PRKDC

1.54e-052137221135032
Pubmed

Defining the membrane proteome of NK cells.

NAA15 NUP107 DOCK10 ARFGEF2 POR CCDC77 BIRC6 ITPR1 NUP205 PTPRC UBR5 PI4KA PRKDC MED17 ACAP2 RPL5

1.55e-0511681371619946888
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

ANKFY1 NUP107 CCT3 BIRC6 NUP205 UBE2O UBR5 PI4KA VPS35 KCTD2 PRKDC

1.74e-055711371137167062
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYH10 NUP107 CCT3 POR USP46 CCDC77 BIRC6 ITPR1 PTPRC FDFT1 PI4KA SVIL ENAH CDK5RAP2 PIBF1

1.78e-0510491371527880917
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

MYH10 NAA15 CCT3 BMP2K NUP205 FDFT1 PI4KA VPS35 MACF1 PRKDC PLEC RPL5

2.50e-057071371219738201
Pubmed

A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.

KALRN COBLL1 CCDC149 FDFT1

2.52e-0543137425130324
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYH10 ANKFY1 CCT3 KALRN HECTD4 CHD8 UBE2O UBR5 PI4KA SVIL ENAH CDK5RAP2 MACF1 UNC79

2.87e-059631371428671696
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP6 ANKFY1 KALRN GAS7 BIRC6 FDFT1 CDK5RAP2 MACF1 PLEC ZNF417

2.95e-054971371023414517
Pubmed

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.

MYH10 MYO1E MYO7B PLEC

3.03e-0545137422114352
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

MYH10 CCT3 MYO1E ARFGEF2 PLEC ACAP2

3.75e-05156137630409884
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ANKFY1 NUP107 CHD8 RFX1 BIRC6 UBR5 CHD6 PLEC CSTPP1

4.44e-05418137934709266
Pubmed

Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis.

CUL4A PCID2

4.61e-053137216467204
Pubmed

Altered homeostasis and development of regulatory T cell subsets represent an IL-2R-dependent risk for diabetes in NOD mice.

PTPRC PRKDC

4.61e-053137229259102
Pubmed

Supervillin binding to myosin II and synergism with anillin are required for cytokinesis.

MYH10 SVIL

4.61e-053137224088567
Pubmed

CDK13/CDC2L5 interacts with L-type cyclins and regulates alternative splicing.

CCNL2 CCNL1

4.61e-053137217261272
Pubmed

Genome-wide analysis of copy-number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes.

COBLL1 RIC1

4.61e-053137236493769
Pubmed

The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.

CHD8 CHD6

4.61e-053137228533432
Pubmed

Characterization of cyclin L1 as an immobile component of the splicing factor compartment.

CCNL2 CCNL1

4.61e-053137217494991
Pubmed

Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection.

CCNL2 CCNL1

4.61e-053137218216018
Pubmed

Relaxin confers cytotrophoblast protection from hypoxia-reoxygenation injury through the phosphatidylinositol 3-kinase-Akt/protein kinase B cell survival pathway.

PTK2B PIK3CB

4.61e-053137228122716
Pubmed

Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer.

ITGA11 PRKDC

4.61e-053137226148229
Pubmed

RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk.

LRRK2 VPS35

4.61e-053137223395371
Pubmed

Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling.

PTK2B PIK3CB

4.61e-053137222106345
Pubmed

Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation.

LRRK2 VPS35

4.61e-053137238862989
Pubmed

Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties.

PRKDC MX1

4.61e-053137224307589
Pubmed

The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.

LRRK2 VPS35

4.61e-053137229743203
Pubmed

Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity.

LRRK2 VPS35

4.61e-053137233135724
Pubmed

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation.

CFHR1 CFHR5

4.61e-053137223728178
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

MYH10 ANKFY1 NAA15 NUP107 CCT3 NUP205 UBE2O VPS35 PRKDC PLEC RPL5

4.78e-056381371133239621
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 JADE3 HECTD4 CHD8 SLC7A6 ARHGEF10L NUP205 UBE2O CDK5RAP2 ACAP2

4.98e-055291371014621295
Pubmed

Tagging genes with cassette-exchange sites.

NAA15 OTUB1 ARFGEF2 CHD8 BIRC6 ENAH MACF1 PLEC

5.80e-05335137815741177
Pubmed

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.

CCNL2 UBR5 CCNL1 PRKDC PCID2

5.93e-05104137531365120
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CUL4A PRUNE2 VIPR1 MYH10 SLC38A9 HECTD4 DYNC2I1 MSH5 TMCO4 ZNF587 RIN2 ENAH ARHGEF9 MACF1 CHD6 RIC1 KLHL26

8.16e-0514891371728611215
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

NUP107 BMP2K POR CHD8 RFX1 NUP205 RAB18 FDFT1 VPS35 CCNL1 PRKDC PLEC ZNF417 RPL5 PCID2

8.40e-0512031371529180619
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

NUP107 CCDC77 UBE2O SVIL TENM1 MACF1 CSTPP1

8.71e-05263137734702444
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

CUL4A MYH10 CCT3 VPS35 PLEC PIBF1

8.81e-05182137631067453
Pubmed

CDK11(p58) kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis.

CCNL2 CCNL1

9.19e-054137224436071
Pubmed

Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.

PTK2B PIK3CB

9.19e-054137219416922
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR3 ITPR1

9.19e-054137223413940
Pubmed

Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle.

CCNL2 CCNL1

9.19e-05413722217177
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR3 ITPR1

9.19e-05413729607712
Pubmed

Mapping of Abll within a conserved linkage group on distal mouse chromosome 1 syntenic with human chromosome 1 using an interspecific cross.

ABL2 PTPRC

9.19e-05413722567701
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH10 DNAH9

9.19e-054137211175280
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

9.19e-054137236140829
Pubmed

Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate.

LRRK2 PIK3CB

9.19e-054137225854701
Pubmed

Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia.

PTPRC PRKDC

9.19e-054137236848231
Pubmed

Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl.

PTK2B PIK3CB

9.19e-054137225960397
Pubmed

Autosomal dominant Parkinson's disease: Incidence of mutations in LRRK2, SNCA, VPS35 and GBA genes in Brazil.

LRRK2 VPS35

9.19e-054137227777137
Pubmed

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.

CUL4A OTUB1 UBR5

1.00e-0423137322038470
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

CCT3 GNE BIRC6 UBR5 CCNL1 PLEC MED17

1.00e-04269137729511261
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

NAA15 NUP107 CCT3 OTUB1 UBR5 PRKDC RPL5

1.07e-04272137725315684
Pubmed

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

BIRC6 CDK5RAP2 PRKDC PLEC

1.15e-0463137429162697
Pubmed

DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.

MYO1E SVIL PRKDC PLEC

1.15e-0463137437052853
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

MYH10 CCT3 MYO1E SVIL MACF1 PLEC

1.15e-04191137633762435
Pubmed

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair.

MXRA5 SFXN5 UBE2O PKHD1 PRKDC

1.21e-04121137531900314
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

NAA15 CCT3 MYO1E NUP205 UBE2O FDFT1 MACF1 PRKDC PLEC RPL5 PCID2

1.25e-047111371133022573
Pubmed

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.

AKAP6 VIPR1 CCT3 RYR3 SVIL PRKDC

1.29e-04195137617110338
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

ABL2 KALRN PTK2B UBR5 PI4KA ENAH MACF1

1.31e-04281137728706196
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

MYH10 PTK2B SVIL ENAH

1.46e-0467137429254152
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

CUL4A MYH10 NAA15 CCT3 MYO1E BIRC6 TOE1 RAB18 UBE2O UBR5 VPS35 ENAH MACF1 PRKDC PLEC RPL5

1.49e-0414151371628515276
Pubmed

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.

MYH10 NAA15 CCT3 NUP205 PI4KA VPS35 PRKDC PLEC RPL5

1.51e-04491137922623428
Pubmed

Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin.

CCNL2 CCNL1

1.53e-045137211683997
Pubmed

Factor H-related proteins determine complement-activating surfaces.

CFHR1 CFHR5

1.53e-045137225979655
Pubmed

SCFFBXW7 regulates G2-M progression through control of CCNL1 ubiquitination.

CUL4A CCNL1

1.53e-045137236278408
Pubmed

Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance.

CUL4A CCNL2

1.53e-045137225532805
Pubmed

Proteomic and biochemical studies of calcium- and phosphorylation-dependent calmodulin complexes in Mammalian cells.

ITPR1 UBR5

1.53e-045137217696464
Pubmed

CDK11(p58) protein kinase activity is associated with Bcl-2 down-regulation in pro-apoptosis pathway.

CCNL2 CCNL1

1.53e-045137217516030
GeneFamilyDyneins, axonemal

DNAH10 DNAH9 DNAH11

9.94e-0517983536
GeneFamilyEF-hand domain containing|Plakins

MACF1 PLEC

7.97e-048982939
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

AKAP6 PRUNE2 MYH10 MYO1E KALRN COBLL1 DOCK10 RYR3 ITPR1 SVIL ENAH MACF1

7.01e-131881371234e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 PRUNE2 MYH10 MYO1E KALRN COBLL1 DOCK10 RYR3 ARHGEF10L ITPR1 ENAH MACF1

7.47e-13189137126b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL19A1 DNAH10 KALRN MYO7B NKAIN2 RYR3 PKHD1 TENM1 DNAH9 UNC79 DNAH11

1.34e-11184137112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL19A1 DNAH10 KALRN MYO7B NKAIN2 RYR3 PKHD1 TENM1 DNAH9 UNC79 DNAH11

1.34e-1118413711ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL19A1 DNAH10 KALRN MYO7B NKAIN2 RYR3 PKHD1 TENM1 DNAH9 UNC79 DNAH11

1.34e-11184137112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 PRUNE2 MYH10 MYO1E KALRN COBLL1 ITPR1 ENAH PDE5A

5.73e-091831379cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

AKAP6 PRUNE2 MYH10 MYO1E KALRN COBLL1 ITPR1 PDE5A

1.03e-071831378818fd886e0188091310825f9145fa53328f2c979
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

ANKFY1 DOCK10 SLC7A6 BIRC6 PTPRC ZNF587 MACF1 PRKDC

1.12e-071851378a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ANKFY1 DOCK10 SLC7A6 BIRC6 PTPRC ZNF587 MACF1 PRKDC

1.16e-0718613788571956890fc9894d766ba294a28e376b4aba428
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ANKFY1 DOCK10 ARFGEF2 SLC7A6 BIRC6 PTPRC MACF1 PRKDC

1.43e-0719113789454f642c3621370fa23640b631301346b300950
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMPD3 KALRN ZFP57 DYNC2I1 TEX14 RYR3 KLHL8

8.43e-071661377bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMPD3 KALRN ZFP57 DYNC2I1 TEX14 RYR3 KLHL8

8.43e-0716613775e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL19A1 DNAH10 RYR3 PKHD1 DNAH9 UNC79 DNAH11

9.51e-07169137712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AKAP6 PRUNE2 MYH10 KALRN ARHGEF10L SVIL PDE5A

1.11e-061731377cb6389536195443633adb06e5f1b7483530773d1
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1E BMP2K LRRK2 DOCK10 PTPRC CCNL1 MACF1

1.56e-061821377eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COBLL1 ZFP57 NPAS3 STK32A GLP1R SVIL

2.37e-06124137636dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 PRUNE2 ITGA11 MYH10 KALRN ARHGEF10L ENAH

2.64e-061971377bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellfacs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP107 CXorf38 COBLL1 HAUS3 UBE2O NEK8

1.19e-0516413761d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP107 CXorf38 COBLL1 HAUS3 UBE2O NEK8

1.19e-051641376bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHR LRRK2 RYR3 UNC5CL PKHD1 TENM1

1.19e-0516413761cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

COL19A1 ZFP57 NPAS3 STK32A PDE5A CHD6

1.41e-051691376c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

AKAP6 PRUNE2 MYH10 KALRN RYR3 PDE5A

1.61e-051731376a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellfacs|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 OTUB1 GAS7 SLC7A6 BIRC6 PLEC

1.71e-05175137653e96956019f984decc1c81376ebc88fbf3c4d40
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

AKAP6 PRUNE2 ITGA11 MYH10 KALRN SVIL

2.01e-051801376d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1E BMP2K LRRK2 PTPRC CCNL1 MACF1

2.20e-05183137628cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1E BMP2K LRRK2 PTPRC CCNL1 MACF1

2.20e-0518313763fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

AKAP6 PRUNE2 MYH10 KALRN ENAH PDE5A

2.49e-051871376464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

DOCK10 BIRC6 ITPR1 PTPRC CCNL1 MACF1

2.57e-051881376ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRUNE2 COL19A1 SVIL ENAH PDE5A DNAH11

2.57e-051881376879de94924de978478696fc7838e05a4d795b905
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRUNE2 COL19A1 SVIL ENAH PDE5A DNAH11

2.64e-051891376ab7ece0a517499b70b7754720d3e434765363af6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 GNE LRRK2 PIK3CB PKHD1 DNAH11

2.64e-051891376904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

MYH10 MXRA5 MYO1E COBLL1 ARHGEF10L PKHD1

2.97e-051931376738689d009e4b118d7ce3171a207294b95cbe78b
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRUNE2 RYR3 SVIL ENAH MACF1 PDE5A

2.97e-0519313760256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

ITGA11 MYH10 MXRA5 GAS7 ENAH MUSK

3.06e-05194137603a269f75a481ea54aea8e6444605db8d6df493d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KALRN DOCK10 GAS7 NKAIN2 ENAH MACF1

3.06e-051941376b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

ABL2 COL19A1 LRRK2 GAS7 OR2B11 PTK2B

3.06e-0519413767d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KALRN DOCK10 GAS7 NKAIN2 ENAH MACF1

3.15e-0519513760e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRRK2 GPAM STK32A UNC5CL CCNL1 PIBF1

3.43e-051981376285f729140b1df029c24f6ca1d2438470ac51794
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COBLL1 ZFP57 NPAS3 GLP1R SVIL

7.05e-0513913759e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KALRN LRRK2 PTPRC CCDC15 PRKDC

1.04e-041511375b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 COL19A1 LRRK2 PKHD1 DNAH11

1.11e-041531375d6526d17826470534b766df144c74e73eb83fdad
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

AKAP6 KALRN ZFP57 RYR3 ITPR1

1.11e-041531375ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKFY1 DNAH10 DOCK10 PTPRC MX1

1.25e-041571375ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 JADE3 PIWIL2 PKDREJ CCDC149

1.29e-041581375f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 JADE3 PIWIL2 PKDREJ CCDC149

1.29e-0415813758c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN DYNC2I1 TEX14 RYR3 KLHL8

1.33e-0415913754000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN DYNC2I1 TEX14 RYR3 KLHL8

1.33e-0415913757619d0d49738dd08daf01b42664691a5323aa793
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 MYO7B RYR3 PKHD1 DNAH9

1.37e-041601375c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 MYO7B RYR3 PKHD1 DNAH9

1.37e-04160137525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

PRUNE2 MYH10 KALRN RYR3 SNX31

1.41e-04161137564891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFP57 DOCK10 NPAS3 STK32A PDE5A

1.41e-0416113753b5d7a3dab479c6959a428f3954dedd989900276
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 SLC38A9 RYR3 SVIL DNAH11

1.49e-0416313751e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K DOCK10 PTK2B PTPRC MX1

1.58e-0416513758a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL19A1 BMP2K COBLL1 PIWIL2 ITPR1

1.58e-04165137583095377aedf960c05baa523869bdbd2b0a05f2d
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JADE3 ZFP57 RADIL LIPH PRKDC

1.62e-04166137511b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JADE3 ZFP57 RADIL LIPH PRKDC

1.62e-041661375fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

KALRN GPAM UNC5CL CCDC15 BAHCC1

1.62e-04166137596d92316cee20b722fe782db9dafcceb8f2c220b
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

COL19A1 COBLL1 ITPR1 PTPRC MACF1

1.76e-041691375c3a6179a64589a370108fea809b157839347759c
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

AMPD3 ABL2 ZNF558 RIC1 KLHL26

1.76e-0416913756abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E COBLL1 ZFP57 PKDREJ SFXN5

1.76e-0416913750332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 LRRK2 ARHGEF10L PKHD1 DNAH11

1.81e-0417013755d5f208682be21ed58320f5fc083a7898f8712da
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFHR1 RYR3 SVIL ENAH PDE5A

1.86e-041711375fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABL2 DNAH10 CCR9 MUSK

1.87e-04921374d2c1d25e5bb6ba4f406e916e3c0a5ad05492e59d
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABL2 DNAH10 CCR9 MUSK

1.87e-04921374926e02725a03d8473eda25d4aef63e34a6566224
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

AKAP6 MYH10 KALRN GLP1R ENAH

1.92e-041721375c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K DOCK10 GAS7 PTPRC MACF1

1.97e-041731375869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

AMPD3 ABL2 ZNF558 RIC1 KLHL26

1.97e-041731375d11705e56b6b21eec963ea224717f27680c781ed
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K DOCK10 GAS7 PTPRC MACF1

1.97e-0417313750672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K DOCK10 GAS7 PTPRC MACF1

1.97e-041731375870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellBasal_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MXRA5 NKAIN2 UNC5CL SNX31 ZNF417

2.02e-041741375a0060be3940043015dcc49a5157de5541aed24a1
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMP2K HECTD4 GAS7 EXTL3 KLHL26

2.08e-0417513751d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BMP2K HECTD4 GAS7 EXTL3 KLHL26

2.08e-041751375427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 COL19A1 LRRK2 PIK3CB UNC5CL

2.13e-04176137533323c97afe509147956b8df9f92ca6b0537e604
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPAM TOE1 UNC5CL RIN2 UNC79

2.13e-04176137530adf8f1638c6244586f8101c2590bb964dfae00
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPAM TOE1 UNC5CL RIN2 UNC79

2.13e-04176137523fa02d4c39e0b8faa1658116d50b6233a952ccc
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AMPD3 COL19A1 MYO7B COBLL1 DNAH11

2.25e-041781375812e261d9cbdc74fafe3c5c3422151c1cfacb22d
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

COL19A1 MYO1E MYO7B HECTD4 PTPRC

2.25e-04178137571ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COBLL1 LRRK2 TEX14 STK32A UNC5CL

2.30e-041791375fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DYNC2I1 ENAH DNAH9 DNAH11

2.36e-0418013751f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MYO1E COBLL1 DOCK10 SFXN5

2.36e-041801375023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-MEP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MYH10 CCT3 NKAIN2 RYR3 RPL5

2.43e-041811375ee207ea171e2ffc22a7f850be57bb118a87e0f81
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 COBLL1 LRRK2 ARHGEF10L PKHD1

2.43e-0418113759d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K CCR9 DOCK10 ARHGEF10L ITPR1

2.43e-0418113757286700396676fdc41d9723979b8b408177aceb9
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 MYO7B UNC5CL PKHD1 TENM1

2.43e-0418113756980ea624151da32b7f537f263e40fcb87a02e81
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS7 NKAIN2 STK32A TENM1 UNC79

2.49e-041821375d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 MYO1E COBLL1 SFXN5

2.49e-041821375f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 COBLL1 LRRK2 ARHGEF10L PKHD1

2.49e-041821375eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS7 NKAIN2 STK32A TENM1 UNC79

2.49e-041821375e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 LRRK2 ARHGEF10L PIK3CB PKHD1

2.55e-041831375738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 MYO7B UNC5CL PKHD1 TENM1

2.55e-0418313756878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NPAS3 USP46 FRMD1 RYR3 DNAH9

2.55e-0418313753c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NPAS3 USP46 FRMD1 RYR3 DNAH9

2.55e-0418313759c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 LRRK2 ARHGEF10L PIK3CB PKHD1

2.55e-04183137592fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

PRUNE2 MYO7B LRRK2 UNC5CL PKHD1

2.62e-04184137551ed1ebfdef45149541917c66cbacad87072e51f
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZNF586 RFX1 VPS35 PDE5A MX1

2.62e-0418413759cbfb9f09476b4d09eb8f92c6f21e449dabcfa98
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 DNAH10 DYNC2I1 DNAH9 DNAH11

2.62e-041841375264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 BIRC6 PTPRC CCNL1 MACF1

2.62e-0418413751154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellCOPD-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

LRRK2 GAS7 NBPF19 OR2B11 PTK2B

2.62e-041841375ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 LRRK2 RYR3 NBPF19 TENM1

2.62e-041841375658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GNE LRRK2 PIK3CB PKHD1 DNAH11

2.62e-041841375da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
Diseaseplatelet component distribution width

CUL4A PRUNE2 BMP2K KALRN COBLL1 LRRK2 DOCK10 UBE2O PTPRC RIN2 SVIL MACF1 PLEC MUSK

5.92e-0675512914EFO_0007984
Diseasered blood cell density measurement

DNAH10 BMP2K KALRN COBLL1 ARFGEF2 HDDC2 NUP205 FOCAD PTPRC UBR5 PKHD1 PLEC KLHL8 PIBF1 MUSK

7.41e-0688012915EFO_0007978
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

ANKFY1 NUP107 MYO1E NUP205

8.75e-06301294C1868672
Diseasemean platelet volume

CUL4A NT5DC4 MYO1E KALRN LRRK2 DOCK10 DYNC2I1 PTPRC PIK3CB TRABD PI4KA SVIL PLEC KLHL8 ACAP2 MUSK

1.02e-05102012916EFO_0004584
Diseasereticulocyte measurement

CUL4A AMPD3 DNAH10 BMP2K COBLL1 HECTD4 ARFGEF2 BIRC6 UBE2O PTPRC ZNF792 FDFT1 NEK8 PDE5A ACAP2 PCID2

1.51e-05105312916EFO_0010700
DiseaseCFHR5 DEFICIENCY

CFHR1 CFHR5

1.90e-0521292C3553720
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

DNAH10 COBLL1 HECTD4 GPAM FDFT1 MACF1 KLHL8 MUSK

2.21e-052641298EFO_0008317, EFO_0020944
Diseasereticulocyte count

AMPD3 DNAH10 BMP2K COBLL1 ZFP57 HECTD4 POR BIRC6 UBE2O PTPRC ZNF792 FDFT1 NEK8 ACAP2 PCID2

5.42e-05104512915EFO_0007986
Diseasemean corpuscular hemoglobin concentration

CUL4A CCT3 BMP2K KALRN COBLL1 HECTD4 ARFGEF2 FOCAD PTPRC UBR5 MACF1 PRKDC PIBF1 MED17 MUSK

1.01e-04110512915EFO_0004528
Diseasepontocerebellar hypoplasia (implicated_via_orthology)

AMPD3 TOE1

1.88e-0451292DOID:0060264 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

NAA15 CHD8 ITPR1 CHD6

2.42e-04691294DOID:1682 (implicated_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

DNAH10 COBLL1 GPAM FDFT1 MACF1 MUSK

2.56e-042001296EFO_0004611, EFO_0020945
Diseaseprocollagen C-endopeptidase enhancer 1 measurement

MUSK DNAH11

2.81e-0461292EFO_0801920
Diseaseunipolar depression, bipolar disorder, mental or behavioural disorder

AMPD3 NPAS3

2.81e-0461292EFO_0000677, EFO_0003761, MONDO_0004985
Diseaseplatelet crit

MYO1E KALRN SLC38A9 LRRK2 DOCK10 GPAM NUP205 PTPRC TRABD SVIL PDE5A PLEC KLHL8

2.83e-0495212913EFO_0007985
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD8 CHD6

3.93e-0471292DOID:0050834 (implicated_via_orthology)
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

DNAH10 COBLL1 FDFT1 TRABD MACF1 MUSK

4.68e-042241296EFO_0004530, EFO_0008317
Diseaseplatelet measurement

NT5DC4 KALRN LRRK2 DOCK10 DYNC2I1 PLEC MUSK

4.87e-043151297EFO_0005036
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

AMPD3 DNAH10 COBLL1 GPAM FDFT1 KLHL8 MUSK

5.44e-043211297EFO_0004612, EFO_0004639
Diseaselymphocyte count

CALR3 DNAH10 KALRN SLC38A9 COBLL1 HECTD4 DOCK10 ITPR1 FOCAD OR2B11 UBE2O PTPRC FDFT1 KCTD2 PLEC ACAP2

6.68e-04146412916EFO_0004587
DiseaseC3 glomerulopathy

CFHR1 CFHR5

6.69e-0491292C4087273
Diseasevenous thromboembolism, response to antineoplastic agent

KALRN PKHD1 RIC1

7.71e-04411293EFO_0004286, GO_0097327
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement

DNAH10 COBLL1 FDFT1 MUSK

8.16e-04951294EFO_0004529, EFO_0008317, EFO_0008596
Diseasemyeloid white cell count

PRUNE2 AMPD3 DNAH10 MYO1E SLC38A9 HECTD4 GPAM PTK2B UBE2O PTPRC ENAH MUSK

8.56e-0493712912EFO_0007988
Diseasecomplement factor H-related protein 3 measurement

AKAP6 CFHR1 KALRN CFHR5 NUP205

9.02e-041691295EFO_0600056
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

COBLL1 GPAM MUSK DNAH11

9.52e-04991294EFO_0004611, EFO_0007878
Diseasehemopexin measurement

CFHR1 CFHR5

1.02e-03111292EFO_0008149
Diseasevery low density lipoprotein cholesterol measurement

DNAH10 COBLL1 FDFT1 KLHL8 MUSK DNAH11

1.02e-032601296EFO_0008317
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement

DNAH10 COBLL1 FDFT1 MUSK

1.23e-031061294EFO_0008317, EFO_0008596
Diseasecoffee consumption measurement

AKAP6 NPAS3 POR BIRC6 PKHD1

1.25e-031821295EFO_0006781
Diseasepolyunsaturated fatty acids to total fatty acids percentage

COBLL1 KLHL8 MUSK

1.38e-03501293EFO_0022303
Diseasecholesteryl esters to total lipids in IDL percentage

COBLL1 GPAM MACF1

1.38e-03501293EFO_0022247
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

DNAH10 COBLL1 BIRC6 FDFT1 MACF1 MUSK

1.38e-032761296EFO_0004612, EFO_0020943
Diseasecholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

DNAH10 COBLL1 FDFT1 MUSK

1.41e-031101294EFO_0008317, EFO_0008596, EFO_0010351
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

DNAH10 COBLL1 FDFT1 MUSK

1.41e-031101294EFO_0008317, EFO_0008591, EFO_0008596
Diseasechylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement

DNAH10 COBLL1 FDFT1 MUSK

1.41e-031101294EFO_0004574, EFO_0008317, EFO_0008596
Diseaselean body mass

AMPD3 TRHR SLC38A9 NPAS3 GPAM CCDC149 PLEC

1.43e-033791297EFO_0004995
Diseaselevel of Sphingomyelin (d34:2) in blood serum

MUSK RIC1

1.43e-03131292OBA_2045174
DiseaseHeschl's gyrus morphology measurement

KALRN COBLL1 CCDC149

1.63e-03531293EFO_0005852
Diseasefatty acid measurement, breast milk measurement, parental genotype effect measurement

SFXN5 MUSK

1.67e-03141292EFO_0005110, EFO_0005939, EFO_0009092
Diseaselevel of Phosphatidylethanolamine (18:1_18:1) in blood serum

MYO1E MUSK

1.67e-03141292OBA_2045142
Diseasealcohol use disorder (implicated_via_orthology)

VIPR1 RYR3 PIK3CB GLP1R UNC79

1.70e-031951295DOID:1574 (implicated_via_orthology)
Diseaseomega-6 polyunsaturated fatty acid measurement

COBLL1 OR2B11 FDFT1 MUSK DNAH11

1.78e-031971295EFO_0005680
Diseasefree cholesterol to total lipids in very large HDL percentage

COBLL1 GPAM MUSK

1.81e-03551293EFO_0022288
Diseaseimmature platelet measurement

KALRN DOCK10 SVIL PLEC

1.88e-031191294EFO_0803541
Diseasetriglycerides in large VLDL measurement

DNAH10 COBLL1 MUSK

1.91e-03561293EFO_0022178
Diseaseglycerate measurement

CCR9 RYR3

1.92e-03151292EFO_0021029
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

DNAH10 COBLL1 GPAM FDFT1 MUSK

2.16e-032061295EFO_0004612, EFO_0020947
Diseasedual specificity mitogen-activated protein kinase kinase 2 measurement

CUL4A PCID2

2.19e-03161292EFO_0008112
DiseaseRolandic epilepsy

KALRN RAB18

2.19e-03161292Orphanet_1945
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

NEK8 PKHD1

2.19e-03161292DOID:0110861 (implicated_via_orthology)
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

AMPD3 COBLL1 GPAM BIRC6 MUSK DNAH11

2.21e-033031296EFO_0004612, EFO_0020945
Diseasecholesterol to total lipids in IDL percentage

COBLL1 GPAM MACF1

2.33e-03601293EFO_0022233
Diseasefree cholesterol to total lipids in medium HDL percentage

COBLL1 GPAM MUSK

2.33e-03601293EFO_0022282
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

COBLL1 GPAM MACF1 KLHL8 MUSK DNAH11

2.36e-033071296EFO_0004612, EFO_0020946
Diseasefree cholesterol in very large VLDL measurement

DNAH10 COBLL1 MUSK

2.44e-03611293EFO_0022274
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

DNAH10 COBLL1

2.47e-03171292EFO_0004611, EFO_0007800
Diseasetotal lipids in very large VLDL measurement

DNAH10 COBLL1 MUSK

2.56e-03621293EFO_0022313
Diseasefree cholesterol in very large HDL measurement

COBLL1 GPAM MUSK

2.56e-03621293EFO_0022273
Diseasephospholipids in very large VLDL measurement

DNAH10 COBLL1 MUSK

2.56e-03621293EFO_0022299
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

DNAH10 COBLL1 FDFT1 MUSK DNAH11

2.60e-032151295EFO_0008317, EFO_0008591
DiseaseMalignant neoplasm of breast

AKAP6 COL19A1 KALRN ARFGEF2 CFHR5 PKDREJ PTPRC PIK3CB TENM1 MROH7 MACF1 DNAH9

2.68e-03107412912C0006142
Diseasesphingosine 1-phosphate measurement

ITPR1 UBE2O

2.77e-03181292EFO_0800185
Diseaseprotein Z-dependent protease inhibitor measurement

CUL4A PCID2

2.77e-03181292EFO_0021849
Diseasesusceptibility to hepatitis B infection measurement

ARFGEF2 ENAH KCTD2

2.80e-03641293EFO_0008405
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

DNAH10 COBLL1 FDFT1 MUSK DNAH11

2.87e-032201295EFO_0004529, EFO_0008317
Diseasecholesterol in very large VLDL measurement

DNAH10 COBLL1 MUSK

2.93e-03651293EFO_0022230
Diseasetotal lipids in very large HDL measurement

COBLL1 GPAM MUSK

3.06e-03661293EFO_0022312
Diseasephospholipids in very large HDL measurement

COBLL1 GPAM MUSK

3.06e-03661293EFO_0022298
Diseasebody mass index, high density lipoprotein cholesterol measurement

DNAH10 COBLL1

3.09e-03191292EFO_0004340, EFO_0004612
Diseasethrombin activatable fibrinolysis inhibitor activation peptide measurement

DOCK10 ITPR1

3.09e-03191292EFO_0008582
Diseaselevel of Phosphatidylethanolamine (18:0_20:4) in blood serum

MYO1E MUSK

3.09e-03191292OBA_2045140
Diseasetriglyceride measurement, body mass index

DNAH10 COBLL1

3.09e-03191292EFO_0004340, EFO_0004530
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

DNAH10 COBLL1 GPAM FDFT1 MUSK

3.10e-032241295EFO_0004574, EFO_0008317
Diseasefatty acid measurement

COBLL1 GAS7 GPAM FDFT1 MACF1 KLHL8 MUSK

3.13e-034361297EFO_0005110
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

DNAH10 COBLL1 GPAM FDFT1 MUSK

3.16e-032251295EFO_0008317, EFO_0010351
Diseasetotal lipids in large VLDL

DNAH10 COBLL1 MUSK

3.19e-03671293EFO_0022175
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

AMPD3 GPAM MACF1

3.19e-03671293EFO_0008595, EFO_0020946
Diseasetriglycerides to phosphoglycerides ratio

DNAH10 COBLL1 GPAM

3.33e-03681293EFO_0022327
Diseasefree cholesterol in large VLDL measurement

DNAH10 COBLL1 MUSK

3.33e-03681293EFO_0022265
Diseaselipid measurement, high density lipoprotein cholesterol measurement

AMPD3 DNAH10 COBLL1 GPAM FDFT1 MUSK

3.37e-033301296EFO_0004529, EFO_0004612
DiseaseBladder Neoplasm

ANKFY1 OR8S1 POR CHD6

3.38e-031401294C0005695
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

DNAH10 COBLL1 FDFT1 MUSK DNAH11

3.40e-032291295EFO_0004639, EFO_0008317
Diseasecoagulation factor measurement

CFHR5 PCID2

3.42e-03201292EFO_0004634
DiseaseSevere Combined Immunodeficiency

PTPRC PRKDC

3.42e-03201292C0085110
Diseasecholesterol in very large HDL measurement

COBLL1 GPAM MUSK

3.47e-03691293EFO_0022229
DiseaseMalignant neoplasm of urinary bladder

ANKFY1 OR8S1 POR CHD6

3.47e-031411294C0005684
Diseasetriglyceride measurement, body fat percentage

DNAH10 COBLL1

3.77e-03211292EFO_0004530, EFO_0007800
Diseaseintrinsic cardiomyopathy (implicated_via_orthology)

CCT3 RPL5

3.77e-03211292DOID:0060036 (implicated_via_orthology)
Diseasetriglyceride measurement, phospholipid measurement

DNAH10 COBLL1 GPAM FDFT1

3.93e-031461294EFO_0004530, EFO_0004639
Diseasebipolar disorder

AKAP6 CUL4A VIPR1 NPAS3 PDE5A KCTD2 PLEC MUSK

3.94e-035771298MONDO_0004985
Diseasephospholipids in large HDL measurement

COBLL1 GPAM MUSK

4.06e-03731293EFO_0022190
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

COBLL1 GPAM FDFT1 MACF1 MUSK

4.08e-032391295EFO_0008317, EFO_0020945
DiseaseParkinson disease

LRRK2 VPS35

4.14e-03221292cv:C0030567
Diseasenon-high density lipoprotein cholesterol measurement

DNAH10 COBLL1 ARFGEF2 POR GPAM FDFT1 UNC5CL MUSK DNAH11

4.19e-037131299EFO_0005689
Diseasefree cholesterol to total lipids in large LDL percentage

COBLL1 GPAM MACF1

4.22e-03741293EFO_0022280

Protein segments in the cluster

PeptideGeneStartEntry
KCQVVAREQYEQMAR

BAHCC1

2591

Q9P281
RVFLLNDMLVCANIN

ARHGEF10L

561

Q9HCE6
SQMVRCLDILEDYLI

CHD8

1156

Q9HCK8
MMVALQEDIQCRYNL

BIRC6

1916

Q9NR09
ICMLRVALATVYFQE

CALR3

11

Q96L12
CNREEVTAVVLLYMA

ABL2

376

P42684
IACIFGMQLERDAYV

ARFGEF2

931

Q9Y6D5
NMYQEQCISLEEELA

CCDC77

361

Q9BR77
YVLVCFQECERMNIL

DNAH11

4281

Q96DT5
CLVLEQMARLQQLYL

C8orf58

196

Q8NAV2
LMCELGNDVINRVYE

ACAP2

466

Q15057
VMYLQVLECERNQTL

CCNL1

206

Q9UK58
VLILMEYCRAGQVVN

BMP2K

126

Q9NSY1
RELYAMDVNRESCQI

COBLL1

211

Q53SF7
FEACRLLQQMIDIAI

ARHGEF9

221

O43307
QIRMAFRYETLCNEL

AMPD3

736

Q01432
LEVIQQNCYLMAAED

CDK5RAP2

501

Q96SN8
QNCYLMAAEDLELRS

CDK5RAP2

506

Q96SN8
ALLARAMVQYSCQEL

MROH7

946

Q68CQ1
LETYCTRNDIVNMLV

RAB18

106

Q9NP72
MVLACYNINDRQEEL

RIC1

551

Q4ADV7
YQECLQLADMVSSER

NUP107

871

P57740
SGVIVRLAQCQVYDM

NUP205

1576

Q92621
LLAVMAYDRFVAICN

OR5D14

116

Q8NGL3
MAVLEEVVLYAFQQC

RADIL

556

Q96JH8
ELNASTLMNYCAEII

ANKFY1

176

Q9P2R3
LLVVMAYDRFVAICN

OR52E4

116

Q8NGH9
VIAVMALDRYVAICD

OR1B1

116

Q8NGR6
ADCVLLVVMAYDQFI

OR10V1

111

Q8NGI7
IYVCGDARNMARDVQ

POR

626

P16435
FARMCLDRQYLAINE

ITPR1

741

Q14643
LMVAILYCFVNNEVQ

GLP1R

396

P43220
FLRAACQVMAVLLEE

DYNC2I1

591

Q8WVS4
LDGEMRNAVCIFYLV

FDFT1

61

P37268
QLMYCVRQNREDIVS

EID3

46

Q8N140
ILQVELVARACCEYM

KLHL8

146

Q9P2G9
MQVGFIDAICLQLYE

PDE5A

816

O76074
DIMEALQYLHNCRVA

KALRN

2786

O60229
MQLVCVLERQIFDFL

NKAIN2

16

Q5VXU1
IVEALLGYEMVQVAC

NEK8

436

Q86SG6
MYEQLRDIAIDNICR

PI4KA

561

P42356
VLMSGNVRCYNIVVE

LRRK2

241

Q5S007
NVRCYNIVVEAMKAF

LRRK2

246

Q5S007
LEEMRCQYETLVENN

KRT35

266

Q92764
LCRYDLVLMENVETV

LIPH

426

Q8WWY8
NLRSALTEMCVLYDV

MED17

101

Q9NVC6
LQRCQTYMDIVIVLD

ITGA11

156

Q9UKX5
ECILLVVMAFDRYVA

OR2C1

111

O95371
LEMDVALVQYINQLC

HECTD4

3461

Q9Y4D8
NRNLQTCMEVLEALY

NAA15

796

Q9BXJ9
SDVIMYIQECEGLIR

MACF1

471

Q9UPN3
CIVLAAMALDRYVAI

OR2B11

116

Q5JQS5
FIQRDDLQCFYILNM

NT5DC4

111

Q86YG4
DIDEVQCILANLIYM

PCID2

356

Q5JVF3
VNCLAYDEAIMAQQD

OTUB1

21

Q96FW1
GLCVVRNNEYIFMDL

FRMD1

96

Q8N878
QTLDIMVEDVLCRQY

KLHL26

266

Q53HC5
IDVDALCMENRYLQE

CCDC149

156

Q6ZUS6
ENILVEQLYMCVEFL

DOCK10

1806

Q96BY6
TYEERINLILQMCVE

GNE

441

Q9Y223
LTYMEDAVCQLLENR

CSTPP1

21

Q9H6J7
SQMVRCLDILEDYLI

CHD6

806

Q8TD26
QVISLYMDCNLIARR

COL19A1

181

Q14993
VMYLQVLECERNQHL

CCNL2

201

Q96S94
NADIACLYVILVGEM

EXTL3

231

O43909
CLYAAEGQRLMQERE

CUL4A

241

Q13619
LIMCISVDRYIAIAQ

CCR9

136

P51686
EMARLQLAYICAQHQ

HAUS3

261

Q68CZ6
VSVEVNCRNEYAMIG

CFHR5

291

Q9BXR6
QLDQCEMILQASEYE

HDDC2

141

Q7Z4H3
MVLSELAARLNCAEY

CXorf38

1

Q8TB03
ICQARAAVMVYDDAN

ENAH

6

Q8N8S7
YIVVAFQECGRMNIL

DNAH9

4251

Q9NYC9
CVISREIMENYNIAL

CFHR1

266

Q03591
AENMADLIDGYCRLQ

PTK2B

341

Q14289
YMATICQDLSDVLQI

DNAH10

466

Q8IVF4
QENNVRDLCIAYMLV

SLC38A9

386

Q8NBW4
INIMELAASVCRYDL

JADE3

126

Q92613
AYRCMLQDREDQSIL

MYH10

161

P35580
ALNLLEMIQQECYRD

FOCAD

381

Q5VW36
ILEDMRCQYEALVEN

KRT36

261

O76013
VYRVLQCQEEELTQM

KCTD2

186

Q14681
EIRDQETLLMYQLQC

MSH5

496

O43196
ANNDIFLYEILRSMC

TRIM49

296

P0CI25
YLLQLMAVCLSQDLE

TEX14

306

Q8IWB6
RQIAVYSENMELCSQ

PRUNE2

291

Q8WUY3
NCYLVSLAVADLMVL

TRHR

61

P34981
GARVIYFCLQEMAQE

TMCO4

406

Q5TGY1
EAAIIETNCIYRLMD

SVIL

1556

O95425
FYILEQQCVGLAVDM

NBPF19

1121

A0A087WUL8
YILEQQCVGLAVDMD

NBPF19

1366

A0A087WUL8
FYILEQQCVGLAVDM

NBPF19

2341

A0A087WUL8
YILEQQCVGLAVDMD

NBPF19

2586

A0A087WUL8
FYILEQQCVGLAVDM

NBPF19

3561

A0A087WUL8
LYREHCEAIVDVMVN

RFX1

611

P22670
RNDCVLDVMHAIYQQ

PIWIL2

386

Q8TC59
LAYVVDEGCIIMQER

PKDREJ

1976

Q9NTG1
DDLMRCVDLYNQAQS

GAS7

381

O60861
IMEAIIACSLYAVLN

GPAM

581

Q9HCL2
ICQIAYARIEGDMIV

RPL5

61

P46777
RILQMEEEYIQQLCE

CCT3

266

P49368
QYDNVGRMVICDIRV

TENM1

2126

Q9UKZ4
RVNMDLNIIYCENRI

NPAS3

336

Q8IXF0
YVQCDLTVAMATEQL

PKHD1

1816

P08F94
CLRQMSDEELSQYLL

PIK3CB

626

P42338
FICELVMALDYLQNQ

STK32A

126

Q8WU08
ALINVLLAVNMVFCE

OR8S1

156

Q8NH09
DCRVAVDLLYMQAIQ

SNX31

216

Q8N9S9
CYLEAQRDAVEQMSL

AKAP6

916

Q13023
QECYAAEQRILRMNF

CCDC15

811

Q0P6D6
ILSERQDMYQCLVEG

ZNF511

136

Q8NB15
VLTYVIAQCDMLELD

RIN2

701

Q8WYP3
LLNEAQRCLYRDVML

ZNF586

31

Q9NXT0
ARLQEECDYVQMIEV

VIPR1

31

P32241
DCLDASQRVLYQDVM

ZFP57

31

Q9NU63
MLALVLNCIDRLNVY

RYR3

481

Q15413
DVVVVELCQYRVSML

TRABD

101

Q9H4I3
ALAQEYLMECIIQVF

VPS35

256

Q96QK1
TLYRDVMLENCRNLA

ZNF558

66

Q96NG5
QRCLYRDVMLENLAL

ZNF587

36

Q96SQ5
MCQDLRVLNAVRDYH

VPS16

421

Q9H269
EYLNRQNMELSVRCA

PIBF1

321

Q8WXW3
QRCLYRDVMLENLAL

ZNF417

36

Q8TAU3
NSRCYNEMALIRVVQ

UBE2O

1096

Q9C0C9
TVMERLDCASAIQNY

UNC5CL

476

Q8IV45
NTEENLTYLQLMERC

PLEC

4231

Q15149
VLCRVEGMTELYFQL

PRKDC

2401

P78527
LFNCTMALIYLIVED

SLC7A6

371

Q92536
NLDRMYDLVAVVVHC

USP46

291

P62068
AEQLYRLEMEFQRCQ

VAX2

111

Q9UIW0
LDEAQRLLYCDVMLE

ZNF792

31

Q3KQV3
CRDIANMIILLVYVR

ZBED9

906

Q6R2W3
ANICNVVLMRYGELE

SFXN5

211

Q8TD22
YRDVMLENCRNLASL

ZNF557

61

Q8N988
QRCLMVQVEAQYILI

PTPRC

891

P08575
YLAQVFNLTLLCMEE

TOE1

116

Q96GM8
EACRQYLMNLEQAVV

UBR5

886

O95071
AAMECVRQYINEVLD

UNC79

2316

Q9P2D8
EYVMQENCGIVVSLR

ZNF641

136

Q96N77
IRLHFQMEQIVYCQD

MX1

521

P20591
YRNMIIDRENQCVII

MYO1E

96

Q12965
GLYQCIAQVRDEMDR

MXRA5

551

Q9NR99
EQLCIARQVAAGMAY

MUSK

701

O15146
IACQIFVAILRYMGD

MYO7B

1666

Q6PIF6