Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ARM-type_fold	PPP4R1 TTI1 THADA INTS7	3.58e-03	339	35	4	IPR016024
Domain	RhoGAP	ARHGAP4 ARHGAP27	6.01e-03	62	35	2	SM00324
Domain	RhoGAP	ARHGAP4 ARHGAP27	6.20e-03	63	35	2	PF00620
Domain	RHOGAP	ARHGAP4 ARHGAP27	6.39e-03	64	35	2	PS50238
Domain	RhoGAP_dom	ARHGAP4 ARHGAP27	6.39e-03	64	35	2	IPR000198
Domain	-	ARHGAP4 ARHGAP27	6.39e-03	64	35	2	1.10.555.10
Domain	-	PPP4R1 TTI1 INTS7	8.19e-03	222	35	3	1.25.10.10
Domain	-	INTS14 SEC24C	8.47e-03	74	35	2	3.40.50.410
Domain	Rho_GTPase_activation_prot	ARHGAP4 ARHGAP27	1.18e-02	88	35	2	IPR008936
Pubmed	Candidate Oncogenes, ARHGAP4, NOS3, and OR51B5, for the Development of Scirrhous-type Gastric Cancer.	ARHGAP4 OR51B5	2.95e-06	3	35	2	36288877
Pubmed	Structure of the catalytic core of the Integrator complex.	INTS14 INTS7	8.89e-05	14	35	2	33548203
Pubmed	The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts.	INTS14 INTS7	8.89e-05	14	35	2	32697989
Pubmed	INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.	INTS14 INTS7	8.89e-05	14	35	2	32647223
Pubmed	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.	OR51B5 OR51I1	1.02e-04	15	35	2	11121057
Pubmed	Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.	OR51B5 OR51I1	1.02e-04	15	35	2	10220430
Pubmed	Novel interactors and a role for supervillin in early cytokinesis.	LMNA PCNX3	3.66e-04	28	35	2	20309963
Pubmed	Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.	ARHGAP4 LMNA KIAA0825	5.51e-04	159	35	3	22751105
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PNPT1 THADA LMNA SEC24C DEGS1 POLD1 PARL	6.04e-04	1487	35	7	33957083
Cytoband	11q12	UBE2L6 MS4A5	1.17e-04	21	35	2	11q12
GeneFamily	Integrator complex	INTS14 INTS7	2.76e-04	15	30	2	1366
GeneFamily	Olfactory receptors, family 51	OR51B5 OR51I1	2.41e-03	44	30	2	164
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP4 ARHGAP27	3.10e-03	50	30	2	721
Disease	drug-Induced dyskinesia, response to levodopa	EXTL3 CBFA2T3	1.95e-04	18	34	2	EFO_0010747, EFO_1000904
Disease	Developmental delay (disorder)	PNPT1 DEGS1	8.37e-04	37	34	2	C0424605
Disease	white matter microstructure measurement	CATSPERB EXTL3 ARHGAP27 FZD2	1.02e-03	390	34	4	EFO_0005674
Disease	stromal cell-derived factor 1 alpha measurement	THADA CBFA2T3	1.13e-03	43	34	2	EFO_0008293

Protein segments in the cluster

Peptide	Gene	Start	Entry
TPRLFSIKPFYRPLG	AKAP2	346	Q9Y2D5
VPRFKFPITQYPVSL	CATSPERB	941	Q9H7T0
TIKRFPYPPFIADPF	ABCA3	241	Q99758
RLLPPLYSLVFIFGF	CCR5	31	P51681
VRFPRLFQKYPFPIL	INTS7	46	Q9NVH2
DPLLTYRFPPKFTLK	LMNA	476	P02545
LPPPVKYFFFLSERK	KIAA0825	986	Q8IV33
FLLIFPFLLYMVLPP	PCNX3	41	Q9H6A9
FVSVVPPIRPLYFFL	OR51B5	151	Q9H339
TTLFPFPFVVKRLPF	OR51I1	156	Q9H343
PLRGFVLAPLFVYLF	FZD2	411	Q14332
YYLGLLPFIPIPEKF	GDPD3	211	Q7L5L3
VIFLFTLLKPYPRFP	MS4A5	66	Q9H3V2
TLLKPYPRFPFIFLS	MS4A5	71	Q9H3V2
FIAYPHLRIRTKPFP	COX6A1	71	P12074
FPLRPFVIPFLKANL	CBFA2T3	226	O75081
MVRPYPLIYFLFLPL	QRFP	1	P83859
PPLQLLLFVLFFAIY	OR6P1	21	Q8NGX9
LLPKPRVPYPRFSRF	ICE2	86	Q659A1
IPILLIPYFLLFSKF	DGAT2L6	31	Q6ZPD8
FLPLIYFVVTRKNPF	SLC1A2	331	P43004
IPPQVPVKRKYLFTF	EXTL3	331	O43909
RFPLPFPFPSKLYIM	INTS14	141	Q96SY0
ESFPLKFFLRYRPLI	CNTFR	236	P26992
QPLFYAFRPLFINPK	DEGS1	166	O15121
AFRPLFINPKPITYL	DEGS1	171	O15121
FFYPRLLPLTKSPVE	SEC24C	946	P53992
FPSPIRLEFEKVYFP	POLD1	786	P28340
SPYPIRSLIKPLFFT	PARL	91	Q9H300
FSRFPELYPFLLKQL	THADA	1286	Q6YHU6
RPSIPYAFSKFLLPI	PPP4R1	121	Q8TF05
PFFPESPRYLLIQKK	SLC2A5	211	P22732
LKLFFRELPEPLFPF	ARHGAP27	771	Q6ZUM4
KALYPVIPRDFPFTI	PNPT1	456	Q8TCS8
LKLYFRSLEPPLFPP	ARHGAP4	581	P98171
FNLRISFPPEYPFKP	UBE2L6	51	O14933
KFLYFLRSRVPGLPP	SOCS7	486	O14512
YILFPLRFTLKTPGP	TTI1	51	O43156