Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	TEAD-YAP complex	TEAD2 TEAD1	1.15e-04	3	130	2	GO:0140552
GeneOntologyCellularComponent	external encapsulating structure	GPLD1 PSAP ADAMTS1 PKHD1L1 LRIG3 CLC PXDN SMC3 ADAMTS16 ADAMTS20 MMP2 MMP9 FBN3	2.37e-04	658	130	13	GO:0030312
GeneOntologyCellularComponent	CKM complex	CDK8 CDK19	3.79e-04	5	130	2	GO:1990508
GeneOntologyCellularComponent	microtubule associated complex	DNAH2 ACTR1B ACTR1A DNAH17 RP1 KIF13A	5.17e-04	161	130	6	GO:0005875
MousePheno	alkalosis	HIF1AN BSND SCNN1B	1.15e-05	7	98	3	MP:0003028
MousePheno	fused cornea and lens	MYO10 PXDN RAB24 ABCG2	2.17e-05	24	98	4	MP:0001307
MousePheno	decreased susceptibility to induced aneurysm formation	PIAS3 MMP9	4.86e-05	2	98	2	MP:0031273
Domain	TEA_1	TEAD2 TEAD1 TEAD3	1.28e-06	4	129	3	PS00554
Domain	TEA_2	TEAD2 TEAD1 TEAD3	1.28e-06	4	129	3	PS51088
Domain	TEA	TEAD2 TEAD1 TEAD3	1.28e-06	4	129	3	PF01285
Domain	TEA/ATTS_dom	TEAD2 TEAD1 TEAD3	1.28e-06	4	129	3	IPR000818
Domain	TEF_metazoa	TEAD2 TEAD1 TEAD3	1.28e-06	4	129	3	IPR016361
Domain	TEA	TEAD2 TEAD1 TEAD3	1.28e-06	4	129	3	SM00426
Domain	Arp1	ACTR1B ACTR1A	4.73e-05	2	129	2	IPR029909
Domain	-	IGF2R MMP2 MMP9	8.75e-05	13	129	3	2.10.10.10
Domain	FN_type2_col-bd	IGF2R MMP2 MMP9	1.11e-04	14	129	3	IPR000562
Domain	FN2_2	IGF2R MMP2 MMP9	1.11e-04	14	129	3	PS51092
Domain	FN2_1	IGF2R MMP2 MMP9	1.11e-04	14	129	3	PS00023
Domain	fn2	IGF2R MMP2 MMP9	1.11e-04	14	129	3	PF00040
Domain	FN2	IGF2R MMP2 MMP9	1.11e-04	14	129	3	SM00059
Domain	-	ADAMTS1 ADAMTS16 ADAMTS20 MMP2 MMP9	2.45e-04	81	129	5	3.40.390.10
Domain	MetalloPept_cat_dom	ADAMTS1 ADAMTS16 ADAMTS20 MMP2 MMP9	2.45e-04	81	129	5	IPR024079
Domain	ADAM_spacer1	ADAMTS1 ADAMTS16 ADAMTS20	5.15e-04	23	129	3	IPR010294
Domain	ADAM_spacer1	ADAMTS1 ADAMTS16 ADAMTS20	5.15e-04	23	129	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS1 ADAMTS16 ADAMTS20	5.86e-04	24	129	3	IPR013273
Domain	ZINC_PROTEASE	ADAMTS1 ADAMTS16 ADAMTS20 MMP2 MMP9	5.91e-04	98	129	5	PS00142
Domain	SMC_hinge	SMCHD1 SMC3	6.97e-04	6	129	2	SM00968
Domain	SMC_hinge	SMCHD1 SMC3	6.97e-04	6	129	2	PF06470
Domain	SMC_hinge	SMCHD1 SMC3	6.97e-04	6	129	2	IPR010935
Domain	Ski_Sno	SKIDA1 SKIL	9.72e-04	7	129	2	PF02437
Domain	-	SKIDA1 SKIL	9.72e-04	7	129	2	3.10.260.20
Domain	Transform_Ski	SKIDA1 SKIL	9.72e-04	7	129	2	IPR003380
Pathway	WP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS	TEAD2 TEAD1 TEAD3 SKIL	6.76e-06	18	100	4	M39825
Pathway	REACTOME_RUNX3_REGULATES_YAP1_MEDIATED_TRANSCRIPTION	TEAD2 TEAD1 TEAD3	6.82e-06	6	100	3	MM15544
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH2 ACTR1B ACTR1A DNAH17 HTT	1.58e-05	45	100	5	M47670
Pathway	REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	TEAD2 TEAD1 TEAD3	1.89e-05	8	100	3	MM14816
Pathway	REACTOME_RUNX3_REGULATES_YAP1_MEDIATED_TRANSCRIPTION	TEAD2 TEAD1 TEAD3	1.89e-05	8	100	3	M27823
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH2 ACTR1B ACTR1A DNAH17	3.69e-05	27	100	4	M47755
Pathway	REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	TEAD2 TEAD1 TEAD3	1.48e-04	15	100	3	M603
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	DNAH2 ACTR1B ACTR1A DNAH17	2.38e-04	43	100	4	M47669
Pathway	WP_MIR5093P_ALTERATION_OF_YAP1ECM_AXIS	TEAD2 TEAD1 TEAD3	2.62e-04	18	100	3	M39421
Pathway	WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS	TEAD2 TEAD1 TEAD3 ITGB5	3.36e-04	47	100	4	M39829
Pathway	WP_HIPPOYAP_SIGNALING	TEAD2 TEAD1 TEAD3	4.84e-04	22	100	3	M39821
Pubmed	MMP production in human fibrosarcoma cells and their invasiveness are regulated by group IB secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2.	PLA2G1B MMP2 MMP9	5.47e-08	3	133	3	17981679
Pubmed	A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain.	TEAD2 TEAD1 TEAD3	2.18e-07	4	133	3	8702974
Pubmed	Comparative expression analysis of TEADs and their splice variants in mouse embryonic stem cells.	TEAD2 TEAD1 TEAD3	2.18e-07	4	133	3	36516960
Pubmed	Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis.	TEAD2 TEAD1 TEAD3	2.18e-07	4	133	3	9889009
Pubmed	The TEA domain: a novel, highly conserved DNA-binding motif.	TEAD2 TEAD1 TEAD3	2.18e-07	4	133	3	2070413
Pubmed	Tead transcription factors differentially regulate cortical development.	TEAD2 TEAD1 TEAD3	2.18e-07	4	133	3	32170161
Pubmed	Transcription factor mTEAD-2 is selectively expressed at the beginning of zygotic gene expression in the mouse.	TEAD2 TEAD1 TEAD3	2.18e-07	4	133	3	9169843
Pubmed	Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro.	TEAD2 TEAD1 TEAD3	5.44e-07	5	133	3	9671946
Pubmed	Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments.	TEAD2 TEAD1 TEAD3	5.44e-07	5	133	3	21527258
Pubmed	TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.	TEAD2 TEAD1 TEAD3	5.44e-07	5	133	3	19324877
Pubmed	Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.	TEAD2 TEAD1 TEAD3	5.44e-07	5	133	3	22677547
Pubmed	TEAD mediates YAP-dependent gene induction and growth control.	TEAD2 TEAD1 TEAD3	5.44e-07	5	133	3	18579750
Pubmed	TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation.	TEAD2 TEAD1 TEAD3	5.44e-07	5	133	3	10518497
Pubmed	TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm.	TEAD2 TEAD1 TEAD3	1.08e-06	6	133	3	11358867
Pubmed	Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor.	TEAD2 TEAD1 TEAD3	1.08e-06	6	133	3	25995450
Pubmed	Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3.	TEAD2 TEAD1 TEAD3	1.89e-06	7	133	3	14736747
Pubmed	Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor.	TEAD2 TEAD1 TEAD3	1.89e-06	7	133	3	16207754
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MON2 MYO10 STXBP5 DOCK9 CDK19 LRIG3 PXDN SLIT1 CACNA1H LRRC7	4.06e-06	407	133	10	12693553
Pubmed	Polymorphisms in angiogenesis-related genes and prostate cancer.	HIF1AN MMP2 MMP9	4.52e-06	9	133	3	18398039
Pubmed	Mechanosignalling via integrins directs fate decisions of pancreatic progenitors.	TEAD2 PDX1 TEAD1 TEAD3	6.76e-06	32	133	4	30487608
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR11H4 OR4A8 OR10G3 OR4A5 OR4K15	9.88e-06	74	133	5	15081110
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS1 ADAMTS16 ADAMTS20 MMP2 MMP9	1.06e-05	75	133	5	20637190
Pubmed	Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.	ADAMTS1 RLF RBPJ MMP2	1.36e-05	38	133	4	29743679
Pubmed	Curcumin induces apoptosis and suppresses invasion through MAPK and MMP signaling in human monocytic leukemia SHI-1 cells.	MMP2 MMP9	1.45e-05	2	133	2	26134921
Pubmed	Association between the polymorphisms in MMP-2 and MMP-9 with adiposity and mammographic features.	MMP2 MMP9	1.45e-05	2	133	2	32394348
Pubmed	Matrix metalloproteinase-9 facilitates glial scar formation in the injured spinal cord.	MMP2 MMP9	1.45e-05	2	133	2	19074020
Pubmed	Increased restenosis rate after implantation of drug-eluting stents in patients with elevated serum activity of matrix metalloproteinase-2 and -9.	MMP2 MMP9	1.45e-05	2	133	2	20129576
Pubmed	Increased activity and expression of gelatinases in ischemic colitis.	MMP2 MMP9	1.45e-05	2	133	2	17089188
Pubmed	Genetic variation in matrix metalloproteinase MMP2 and MMP9 as a risk factor for idiopathic recurrent spontaneous abortions in an Indian population.	MMP2 MMP9	1.45e-05	2	133	2	28500450
Pubmed	Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse.	MMP2 MMP9	1.45e-05	2	133	2	26588471
Pubmed	Expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in recurrent chronic rhinosinusitis with nasal polyposis.	MMP2 MMP9	1.45e-05	2	133	2	23257253
Pubmed	MMP-2/MMP-9 plasma level and brain expression in cerebral amyloid angiopathy-associated hemorrhagic stroke.	MMP2 MMP9	1.45e-05	2	133	2	21707819
Pubmed	Matrix metalloproteinase (MMP)-9: A realiable marker for inflammation in early human trichinellosis.	MMP2 MMP9	1.45e-05	2	133	2	27117947
Pubmed	In vivo biodistribution of radiolabeled MMP-2/9 activatable cell-penetrating peptide probes in tumor-bearing mice.	MMP2 MMP9	1.45e-05	2	133	2	24823643
Pubmed	Comparison of the prognostic value of matrix metalloproteinases 2 and 9 in cutaneous melanoma.	MMP2 MMP9	1.45e-05	2	133	2	18187184
Pubmed	Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study.	MMP2 MMP9	1.45e-05	2	133	2	26097608
Pubmed	Serum MMP-2 and MMP-9 in patients with Behçet's disease: do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?	MMP2 MMP9	1.45e-05	2	133	2	17949555
Pubmed	Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9.	MMP2 MMP9	1.45e-05	2	133	2	19509016
Pubmed	Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9.	MMP2 MMP9	1.45e-05	2	133	2	20372784
Pubmed	Implication of matrix metalloproteinases 2 and 9 in ceramide 1-phosphate-stimulated macrophage migration.	MMP2 MMP9	1.45e-05	2	133	2	27164414
Pubmed	Genetic polymorphisms in the MMP-2 and MMP-9 genes and breast cancer phenotype.	MMP2 MMP9	1.45e-05	2	133	2	15609121
Pubmed	Role of gelatinases in disuse-induced skeletal muscle atrophy.	MMP2 MMP9	1.45e-05	2	133	2	19790245
Pubmed	Collagenase expression and activity is modulated by the interaction of collagen types, hypoxia, and nutrition in human lung cells.	MMP2 MMP9	1.45e-05	2	133	2	15672417
Pubmed	Active form of gelatinases in tear fluidin patients with corneal ulcer or ocular burn.	MMP2 MMP9	1.45e-05	2	133	2	12967855
Pubmed	Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthma.	MMP2 MMP9	1.45e-05	2	133	2	10201949
Pubmed	Disruption of CADM1-dependent cell-cell adhesion in human oral squamous cell carcinoma cells results in tumor progression, possibly through an increase of MMP-2 and MMP-9 expression.	MMP2 MMP9	1.45e-05	2	133	2	38030062
Pubmed	Exercise attenuates matrix metalloproteinase activity in preexisting atherosclerotic plaque.	MMP2 MMP9	1.45e-05	2	133	2	21334624
Pubmed	The Inhibitory Effect of C-phycocyanin Containing Protein Extract (C-PC Extract) on Human Matrix Metalloproteinases (MMP-2 and MMP-9) in Hepatocellular Cancer Cell Line (HepG2).	MMP2 MMP9	1.45e-05	2	133	2	28357609
Pubmed	Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.	CDK8 CDK19	1.45e-05	2	133	2	35181333
Pubmed	Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone.	MMP2 MMP9	1.45e-05	2	133	2	21611966
Pubmed	Matrix metalloproteinase variants associated with risk and clinical outcome of esophageal cancer.	MMP2 MMP9	1.45e-05	2	133	2	25966235
Pubmed	Growth factor-enhanced expression and activity of matrix metalloproteases in human non-small cell lung cancer cell lines.	MMP2 MMP9	1.45e-05	2	133	2	14981939
Pubmed	The influence of opioids on matrix metalloproteinase-2 and -9 secretion and mRNA levels in MCF-7 breast cancer cell line.	MMP2 MMP9	1.45e-05	2	133	2	20563853
Pubmed	Modulation of MMP-2 and -9 secretion by cytokines, inducers and inhibitors in human melanoma A-2058 cells.	MMP2 MMP9	1.45e-05	2	133	2	28440509
Pubmed	Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.	MMP2 MMP9	1.45e-05	2	133	2	21958210
Pubmed	Inhibitory effects of tetrandrine on epidermal growth factor-induced invasion and migration in HT29 human colorectal adenocarcinoma cells.	MMP2 MMP9	1.45e-05	2	133	2	26648313
Pubmed	Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer.	MMP2 MMP9	1.45e-05	2	133	2	19574670
Pubmed	Inhibition of MMP-2 and MMP-9 attenuates surgery-induced cognitive impairment in aged mice.	MMP2 MMP9	1.45e-05	2	133	2	37939860
Pubmed	Expression of Matrix Metalloproteinases-2/-9 is Associated With Microvessel Density in Pancreatic Cancer.	MMP2 MMP9	1.45e-05	2	133	2	26866436
Pubmed	Regulatory functions of the Mediator kinases CDK8 and CDK19.	CDK8 CDK19	1.45e-05	2	133	2	30585107
Pubmed	Congenital Muscular Dystrophy 1D Causes Matrix Metalloproteinase Activation And Blood-Brain Barrier Impairment.	MMP2 MMP9	1.45e-05	2	133	2	27915985
Pubmed	The role of MMP-2 and MMP-9 polymorphisms in sporadic intracranial aneurysms.	MMP2 MMP9	1.45e-05	2	133	2	16961137
Pubmed	Prognostic values of tumoral MMP2 and MMP9 overexpression in breast cancer: a systematic review and meta-analysis.	MMP2 MMP9	1.45e-05	2	133	2	33568081
Pubmed	Metalloproteinase-2 and -9 in giant cell arteritis: involvement in vascular remodeling.	MMP2 MMP9	1.45e-05	2	133	2	15998676
Pubmed	Relationships between circulating matrix metalloproteinase-2 and -9 and renal function in patients with chronic kidney disease.	MMP2 MMP9	1.45e-05	2	133	2	16313894
Pubmed	Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques.	MMP2 MMP9	1.45e-05	2	133	2	29190653
Pubmed	[Role of matrix metalloproteinase in transformation of subdural effusion into chronic subdural hematoma].	MMP2 MMP9	1.45e-05	2	133	2	20501425
Pubmed	Matrix metalloproteinase-2 and -9 activities in human keloids, hypertrophic and atrophic scars: a pilot study.	MMP2 MMP9	1.45e-05	2	133	2	19165813
Pubmed	[Association of gene polymorphisms of matrix metalloproteinases with reproductive losses in the first trimester of pregnancy].	MMP2 MMP9	1.45e-05	2	133	2	29369548
Pubmed	Combination of ACY-241 and JQ1 Synergistically Suppresses Metastasis of HNSCC via Regulation of MMP-2 and MMP-9.	MMP2 MMP9	1.45e-05	2	133	2	32961679
Pubmed	GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary.	MMP2 MMP9	1.45e-05	2	133	2	21454403
Pubmed	Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes.	MMP2 MMP9	1.45e-05	2	133	2	18081721
Pubmed	Matrix metalloproteinases MMP2 and MMP9 are produced in early stages of kidney morphogenesis but only MMP9 is required for renal organogenesis in vitro.	MMP2 MMP9	1.45e-05	2	133	2	9087449
Pubmed	Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage.	MMP2 MMP9	1.45e-05	2	133	2	30248101
Pubmed	MMP-2 and MMP-9 as prognostic markers for the early detection of urinary bladder cancer.	MMP2 MMP9	1.45e-05	2	133	2	30548095
Pubmed	Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection.	MMP2 MMP9	1.45e-05	2	133	2	15707406
Pubmed	Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms.	MMP2 MMP9	1.45e-05	2	133	2	12208863
Pubmed	Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma.	MMP2 MMP9	1.45e-05	2	133	2	28633655
Pubmed	Matrix metalloproteinase expression and activity in trophoblast-decidual tissues at organogenesis in CF-1 mouse.	MMP2 MMP9	1.45e-05	2	133	2	22714107
Pubmed	Linking neuron and skin: matrix metalloproteinases in amyotrophic lateral sclerosis (ALS).	MMP2 MMP9	1.45e-05	2	133	2	19523650
Pubmed	Blockade of MMP-2 and MMP-9 inhibits corneal lymphangiogenesis.	MMP2 MMP9	1.45e-05	2	133	2	28669039
Pubmed	Selective hydrolysis of triple-helical substrates by matrix metalloproteinase-2 and -9.	MMP2 MMP9	1.45e-05	2	133	2	12642591
Pubmed	Association of Matrix Metalloproteinase-2 (MMP-2) and MMP-9 Promoter Variants, Their Serum Levels, and Activities with Aortic Valve Calcification (AVC) in a Population from Western Iran.	MMP2 MMP9	1.45e-05	2	133	2	38708584
Pubmed	Expression of matrix metalloproteinases 2 and 9 in human trophoblasts of normal and preeclamptic placentas: preliminary findings.	MMP2 MMP9	1.45e-05	2	133	2	19716817
Pubmed	Red Grape Skin Polyphenols Blunt Matrix Metalloproteinase-2 and -9 Activity and Expression in Cell Models of Vascular Inflammation: Protective Role in Degenerative and Inflammatory Diseases.	MMP2 MMP9	1.45e-05	2	133	2	27589705
Pubmed	Induction of secreted matrix metalloproteinase-9 activity in human melanoma cells by extracellular matrix proteins and cytokines.	MMP2 MMP9	1.45e-05	2	133	2	16718267
Pubmed	Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia.	MMP2 MMP9	1.45e-05	2	133	2	14736853
Pubmed	Expression of matrix metalloproteinases 2 and 9 in donor liver, cirrhotic liver, and acute rejection after human liver transplantation.	MMP2 MMP9	1.45e-05	2	133	2	19100442
Pubmed	SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells.	SIRT1 MMP2	1.45e-05	2	133	2	23038275
Pubmed	[Inhibitory effect of curcumin on MMP-2 and MMP-9 expression induced by polyethylene wear particles and its mechanism].	MMP2 MMP9	1.45e-05	2	133	2	19594013
Pubmed	The Relationship Between MMP-2 -1306C>T and MMP-9 -1562C>T Polymorphisms and the Risk and Prognosis of T-Cell Acute Lymphoblastic Leukemia in a Chinese Population: A Case-Control Study.	MMP2 MMP9	1.45e-05	2	133	2	28719899
Pubmed	Letrozole as a potent inhibitor of cell proliferation and expression of metalloproteinases (MMP-2 and MMP-9) by human epithelial breast cancer cells.	MMP2 MMP9	1.45e-05	2	133	2	12569569
Pubmed	Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.	MMP2 MMP9	1.45e-05	2	133	2	27831901
Pubmed	HIV Transcription Is Independent of Mediator Kinases.	CDK8 CDK19	1.45e-05	2	133	2	31044597
Pubmed	Expression of metalloproteinases (MMP-2 and MMP-9) in basal-cell carcinoma.	MMP2 MMP9	1.45e-05	2	133	2	27406386
Pubmed	A critical role for matrix metalloproteinases in liver regeneration.	MMP2 MMP9	1.45e-05	2	133	2	18222481
Pubmed	Serum levels of matrix metalloproteinase 2 and matrix metalloproteinase 9 elevated in polypoidal choroidal vasculopathy but not in age-related macular degeneration.	MMP2 MMP9	1.45e-05	2	133	2	23559867
Pubmed	Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.	MMP2 MMP9	1.45e-05	2	133	2	19885578
Pubmed	Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation.	MMP2 MMP9	1.45e-05	2	133	2	22402435
Pubmed	Matrix metalloproteinases 2 and 9 are elevated in human preterm laboring uterine myometrium and exacerbate uterine contractility†.	MMP2 MMP9	1.45e-05	2	133	2	30951583
Cytoband	14q11.2	OR4N5 OR11H4 RNASE6 OR10G3 OR4K15	1.88e-04	180	133	5	14q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr11q11	OR4A8 OR4A5 OR4A15	2.17e-04	40	133	3	chr11q11
Cytoband	8p11.23	GOT1L1 DDHD2	5.39e-04	12	133	2	8p11.23
GeneFamily	TEA domain transcription factors	TEAD2 TEAD1 TEAD3	4.92e-07	4	91	3	1183
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS1 ADAMTS16 ADAMTS20	1.13e-04	19	91	3	50
GeneFamily	Cyclin dependent kinases	CDK20 CDK8 CDK19	2.95e-04	26	91	3	496
GeneFamily	Olfactory receptors, family 4	OR4N5 OR4A8 OR4A5 OR4A15 OR4K15	4.87e-04	129	91	5	151
Coexpression	GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_UP	SLC26A3 MYO10 TEAD1 ITGAE IGF2R DPPA4 SERTAD4 RP1 MMP9	4.95e-07	191	130	9	M3310
Coexpression	GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_UP	GPLD1 PGLYRP3 SKIL ITGAE PKHD1L1 PTPN13 CLC SMAD1 HTT	5.40e-07	193	130	9	M9056
Coexpression	SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP	SGMS2 TRUB1 ZFHX4 SLC38A6	9.28e-06	27	130	4	M4447
Coexpression	KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP	IRF6 SKIL BHMT IGF2R MMP2 SMAD1	2.77e-05	118	130	6	M12313
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC26A3 PKHD1L1 DPPA4 ANKAR LRRC7 HYDIN	9.34e-06	162	133	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GPLD1 PSAT1 PKHD1L1 YIPF2 SCNN1B FBN3	1.45e-05	175	133	6	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DOCK9 TEAD3 TEC ITK MEIOC NBEAL2	1.45e-05	175	133	6	a3f8c54c77bce9b035a4835945ab341909be4946
ToppCell	P15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PKHD1L1 RYR3 ZFHX4 ANKAR MMP9 SMAD1	1.45e-05	175	133	6	84d252f3e432231687613299bbea14978bb4b06b
ToppCell	P15-Endothelial-lymphatic_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PKHD1L1 RYR3 ZFHX4 ANKAR MMP9 SMAD1	1.45e-05	175	133	6	a00c6fa9b33640710dd05a3799031147196f0986
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAT1 SLC26A3 RTEL1 NOL6 C1QTNF7 NUP160	1.54e-05	177	133	6	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS1 SCUBE2 ZFHX4 GREB1 C1QTNF7 MMP2	1.81e-05	182	133	6	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TEAD2 BSND TMEM171 PXDN SCUBE2 SCNN1B	1.86e-05	183	133	6	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 RYR3 ZFHX4 ADAMTS16 ADAMTS20 HYDIN	1.92e-05	184	133	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 RYR3 ZFHX4 ADAMTS16 ADAMTS20 HYDIN	1.92e-05	184	133	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 RYR3 ZFHX4 ADAMTS16 ADAMTS20 HYDIN	1.92e-05	184	133	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	TEAD2 BSND TMEM171 SCUBE2 SCNN1B CACNA1H	2.17e-05	188	133	6	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RSPH4A BSND SCUBE2 SCNN1B RP1 HYDIN	2.24e-05	189	133	6	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PSAP CR1 ITGB5 RNASE6 RBPJ LY86	2.37e-05	191	133	6	24d75b7e1d6fb9d24aa7844f584ee888a449841f
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PLCD4 ITGB5 LRIG3 ADAMTS16 GREB1 MMP2	2.37e-05	191	133	6	44b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_1\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SKIDA1 SLCO5A1 RNASE6 NBEAL2 SLIT1 LY86	2.59e-05	194	133	6	5a048bd2af30975fdc57ff40bc49aa5811c830d8
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PTPN13 FBXL16 CLC SCUBE2 SCNN1B RP1	2.74e-05	196	133	6	ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP57 IRF6 PKHD1L1 IGF2R PLA2G1B ATP1B3	2.74e-05	196	133	6	7d5eaed189aa6116f3799be010139fb675ec65e0
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF6 PKHD1L1 IGF2R PLA2G1B ATP1B3 TEC	2.74e-05	196	133	6	dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Transitional_AT2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	TEAD2 BSND TMEM171 PXDN SCUBE2 SCNN1B	2.99e-05	199	133	6	cd581d7330b471431ef427f8a4f5be553f70e068
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TEAD2 ITGB5 PTPN13 ZFHX4 GREB1 MMP2	2.99e-05	199	133	6	6200618e029063486719479c41eaf31798bd13cf
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	RSPH4A IRF6 HIF1AN PTPN13 FBXL16 PLA2G1B	3.07e-05	200	133	6	eac33be484dc443794e66e473f03e98406c2983e
Drug	choline	GPLD1 TEAD2 PLCD4 TRUB1 BHMT IGF2R CLC SMC3 PLA2G1B SMPD2 ATP1B3	2.53e-06	320	131	11	CID000000305
Drug	hexanolamine PAF	PLA2G1B MMP2 MMP9	1.02e-05	8	131	3	CID000132080
Drug	Khellin [82-02-0]; Down 200; 15.4uM; PC3; HG-U133A	CDK8 DOCK9 IRF6 HNRNPUL1 HIF1AN SIRT1 DBF4 NUP160	1.77e-05	195	131	8	1922_DN
Drug	CL 42A	PLA2G1B MMP2 MMP9	2.97e-05	11	131	3	CID000127348
Drug	ND 322	MMP2 MMP9	3.29e-05	2	131	2	ctd:C568509
Drug	AC1Q62J9	MMP2 MMP9	3.29e-05	2	131	2	CID000475273
Drug	Ro 28-2653	MMP2 MMP9	3.29e-05	2	131	2	ctd:C453902
Drug	S 3304	MMP2 MMP9	3.29e-05	2	131	2	ctd:C503948
Drug	pipoxolan	MMP2 MMP9	3.29e-05	2	131	2	ctd:C000121
Drug	matlystatin B	MMP2 MMP9	3.29e-05	2	131	2	CID000132321
Drug	D 609	GPLD1 PLCD4 PLA2G1B SMPD2 MMP2	3.39e-05	64	131	5	CID000002940
Disease	developmental and epileptic encephalopathy 87 (implicated_via_orthology)	CDK8 CDK19	1.87e-05	2	128	2	DOID:0112221 (implicated_via_orthology)
Disease	pyoderma gangrenosum (is_marker_for)	MMP2 MMP9	1.87e-05	2	128	2	DOID:8553 (is_marker_for)
Disease	Sweet syndrome (is_marker_for)	MMP2 MMP9	1.87e-05	2	128	2	DOID:0080746 (is_marker_for)
Disease	heart valve disease (is_marker_for)	MMP2 MMP9	5.59e-05	3	128	2	DOID:4079 (is_marker_for)
Disease	pulmonary embolism (implicated_via_orthology)	MMP2 MMP9	5.59e-05	3	128	2	DOID:9477 (implicated_via_orthology)
Disease	Sturge-Weber syndrome (is_marker_for)	MMP2 MMP9	5.59e-05	3	128	2	DOID:0111563 (is_marker_for)
Disease	squamous cell carcinoma (is_marker_for)	MMP2 MMP9 RPE65	7.34e-05	19	128	3	DOID:1749 (is_marker_for)
Disease	Lupus Nephritis	MMP2 MMP9	1.11e-04	4	128	2	C0024143
Disease	thoracic aortic aneurysm (biomarker_via_orthology)	MMP2 MMP9	1.11e-04	4	128	2	DOID:14004 (biomarker_via_orthology)
Disease	epilepsy (is_marker_for)	SIRT1 MMP9	1.11e-04	4	128	2	DOID:1826 (is_marker_for)
Disease	stomach carcinoma (biomarker_via_orthology)	MMP2 MMP9	1.11e-04	4	128	2	DOID:5517 (biomarker_via_orthology)
Disease	tyrosine-protein kinase TEC measurement	TEC TEC	1.11e-04	4	128	2	EFO_0020830
Disease	renal hypertension (implicated_via_orthology)	MMP2 MMP9	1.85e-04	5	128	2	DOID:1073 (implicated_via_orthology)
Disease	Aortic Rupture	MMP2 MMP9	1.85e-04	5	128	2	C0003496
Disease	adrenoleukodystrophy (is_marker_for)	MMP2 MMP9	1.85e-04	5	128	2	DOID:10588 (is_marker_for)
Disease	Aortic Aneurysm, Ruptured	MMP2 MMP9	1.85e-04	5	128	2	C0741160
Disease	Retinal Diseases	SIRT1 MMP9 RPE65	2.16e-04	27	128	3	C0035309
Disease	pulmonary emphysema (biomarker_via_orthology)	MMP2 MMP9	2.77e-04	6	128	2	DOID:9675 (biomarker_via_orthology)
Disease	Aortic Diseases	MMP2 MMP9	2.77e-04	6	128	2	C0003493
Disease	Neointima Formation	MMP2 MMP9	2.77e-04	6	128	2	C2936381
Disease	Neointima	MMP2 MMP9	2.77e-04	6	128	2	C2936380
Disease	Aortic Aneurysm, Thoracic	MMP2 MMP9	3.87e-04	7	128	2	C0162872
Disease	Aortic Aneurysm, Thoracoabdominal	MMP2 MMP9	3.87e-04	7	128	2	C0340630
Disease	Neonatal diabetes mellitus	ZFP57 PDX1	3.87e-04	7	128	2	cv:C0158981
Disease	cardiomyopathy (is_marker_for)	MMP2 MMP9	3.87e-04	7	128	2	DOID:0050700 (is_marker_for)
Disease	hyperuricemia	TMEM171 ABCG2 ZNF518B	3.96e-04	33	128	3	EFO_0009104
Disease	Bone neoplasms	MMP2 MMP9	5.14e-04	8	128	2	C0005967
Disease	Malignant Bone Neoplasm	MMP2 MMP9	5.14e-04	8	128	2	C0279530
Disease	transient cerebral ischemia (biomarker_via_orthology)	ADAMTS1 PTPN13 MMP2 MMP9 HTT	6.25e-04	157	128	5	DOID:224 (biomarker_via_orthology)
Disease	Marfan Syndrome, Type I	MMP2 MMP9	6.59e-04	9	128	2	C4721845
Disease	abdominal aortic aneurysm (implicated_via_orthology)	MMP2 MMP9	6.59e-04	9	128	2	DOID:7693 (implicated_via_orthology)
Disease	coronary artery disease	CDK8 PSAP DOCK9 HNRNPUL1 ITGB5 BSND IGF2R SF3B3 LRRC7 ABCG2 RP1 MMP9 ATP1B3 NUP160	6.96e-04	1194	128	14	EFO_0001645
Disease	factor VIII measurement	STXBP5 TMEM171 RP1	7.01e-04	40	128	3	EFO_0004630
Disease	Tumoral calcinosis	MMP2 MMP9 LY86	8.09e-04	42	128	3	C0263628
Disease	Calcinosis	MMP2 MMP9 LY86	8.09e-04	42	128	3	C0006663
Disease	Microcalcification	MMP2 MMP9 LY86	8.09e-04	42	128	3	C0521174
Disease	abdominal aortic aneurysm (is_marker_for)	MMP2 MMP9	8.21e-04	10	128	2	DOID:7693 (is_marker_for)
Disease	cholesteatoma (is_marker_for)	MMP2 MMP9	8.21e-04	10	128	2	DOID:869 (is_marker_for)
Disease	triacylglycerol 54:1 measurement	IGF2R ZFHX4	8.21e-04	10	128	2	EFO_0010419
Disease	Marfan Syndrome	MMP2 MMP9	1.00e-03	11	128	2	C0024796
Disease	heart rate variability measurement, response to antipsychotic drug	JAKMIP3 SKIL SF3B3	1.06e-03	46	128	3	EFO_0008003, GO_0097332
Disease	Centriacinar Emphysema	MMP2 MMP9	1.20e-03	12	128	2	C0221227
Disease	Panacinar Emphysema	MMP2 MMP9	1.20e-03	12	128	2	C0264393
Disease	Focal Emphysema	MMP2 MMP9	1.20e-03	12	128	2	C2350878
Disease	intracranial aneurysm (is_implicated_in)	MMP2 MMP9	1.20e-03	12	128	2	DOID:10941 (is_implicated_in)
Disease	focal segmental glomerulosclerosis (biomarker_via_orthology)	MMP2 MMP9	1.20e-03	12	128	2	DOID:1312 (biomarker_via_orthology)
Disease	Streptozotocin Diabetes	PDX1 SIRT1 MMP2 MMP9	1.28e-03	108	128	4	C0038433
Disease	Diabetes Mellitus, Experimental	PDX1 SIRT1 MMP2 MMP9	1.28e-03	108	128	4	C0011853
Disease	Alloxan Diabetes	PDX1 SIRT1 MMP2 MMP9	1.28e-03	108	128	4	C0002152
Disease	cholangiocarcinoma (biomarker_via_orthology)	MMP2 MMP9	1.41e-03	13	128	2	DOID:4947 (biomarker_via_orthology)
Disease	intracranial aneurysm (biomarker_via_orthology)	MMP2 MMP9	1.41e-03	13	128	2	DOID:10941 (biomarker_via_orthology)
Disease	skin melanoma (is_marker_for)	MMP2 MMP9	1.41e-03	13	128	2	DOID:8923 (is_marker_for)
Disease	serum selenium measurement	BHMT KIF13A LY86	1.59e-03	53	128	3	EFO_0005266
Disease	alcohol use disorder (biomarker_via_orthology)	MMP2 MMP9	1.64e-03	14	128	2	DOID:1574 (biomarker_via_orthology)
Disease	Diabetic Neuralgia	MMP2 MMP9	1.64e-03	14	128	2	C0751074
Disease	Diabetic Neuropathies	MMP2 MMP9	1.64e-03	14	128	2	C0011882
Disease	Asymmetric Diabetic Proximal Motor Neuropathy	MMP2 MMP9	1.64e-03	14	128	2	C0271674
Disease	Symmetric Diabetic Proximal Motor Neuropathy	MMP2 MMP9	1.64e-03	14	128	2	C0271673
Disease	Diabetic Mononeuropathy	MMP2 MMP9	1.64e-03	14	128	2	C0271678
Disease	Diabetic Autonomic Neuropathy	MMP2 MMP9	1.64e-03	14	128	2	C0271686
Disease	Diabetic Amyotrophy	MMP2 MMP9	1.64e-03	14	128	2	C0271685
Disease	Diabetic Polyneuropathies	MMP2 MMP9	1.64e-03	14	128	2	C0271680
Disease	intracranial aneurysm (is_marker_for)	MMP2 MMP9	1.64e-03	14	128	2	DOID:10941 (is_marker_for)
Disease	Diabetic Asymmetric Polyneuropathy	MMP2 MMP9	1.64e-03	14	128	2	C0393835
Disease	mean platelet volume	EDC3 PCDHGB3 NUP210L STXBP5 PCDHGA1 NARF TMEM171 MEIOC PRICKLE3 OR4A15 CATSPERG HTT	1.64e-03	1020	128	12	EFO_0004584
Disease	cholesteatoma of middle ear (is_marker_for)	MMP2 MMP9	2.15e-03	16	128	2	DOID:10964 (is_marker_for)
Disease	temporal arteritis (is_implicated_in)	MMP2 MMP9	2.15e-03	16	128	2	DOID:13375 (is_implicated_in)
Disease	endometriosis (biomarker_via_orthology)	MMP2 MMP9	2.15e-03	16	128	2	DOID:289 (biomarker_via_orthology)
Disease	neuroimaging measurement	DOCK9 SKIDA1 ITGB5 HIF1AN SH2D5 ACTR1B ACTR1A OR10G3 ADAMTS20 ABCG2 ATP1B3 HTT	2.42e-03	1069	128	12	EFO_0004346
Disease	Pulmonary Emphysema	MMP2 MMP9	2.43e-03	17	128	2	C0034067
Disease	ocular hypertension (biomarker_via_orthology)	MMP2 MMP9	2.43e-03	17	128	2	DOID:9282 (biomarker_via_orthology)
Disease	hypertrophic cardiomyopathy (is_marker_for)	MMP2 MMP9	2.43e-03	17	128	2	DOID:11984 (is_marker_for)
Disease	Oral Submucous Fibrosis	MMP2 MMP9	2.73e-03	18	128	2	C0029172
Disease	cystathionine measurement	TEC TEC	3.04e-03	19	128	2	EFO_0010474
Disease	factor VIII measurement, Ischemic stroke	STXBP5 TMEM171	3.04e-03	19	128	2	EFO_0004630, HP_0002140
Disease	Alcohol abuse	CDK20 SIRT1 MMP2	3.12e-03	67	128	3	C0085762
Disease	atherosclerosis (biomarker_via_orthology)	SIRT1 MMP2	3.37e-03	20	128	2	DOID:1936 (biomarker_via_orthology)
Disease	ceramide measurement	TEC SLCO5A1 LRIG3 TEC FBN3	3.67e-03	235	128	5	EFO_0010222
Disease	hyperglycemia (biomarker_via_orthology)	PDX1 MMP9	3.71e-03	21	128	2	DOID:4195 (biomarker_via_orthology)
Disease	gastric ulcer (biomarker_via_orthology)	MMP2 MMP9	3.71e-03	21	128	2	DOID:10808 (biomarker_via_orthology)
Disease	carotid artery disease (is_implicated_in)	MMP2 MMP9	4.07e-03	22	128	2	DOID:3407 (is_implicated_in)
Disease	Bronchiectasis	RSPH4A SCNN1B	4.07e-03	22	128	2	C0006267

Protein segments in the cluster

Peptide	Gene	Start	Entry
CNKQGFIDLPEFPFG	BHMT	256	Q93088
APKGIFCNPYNNLIF	CATSPERG	476	Q6ZRH7
CYDNVPQGIFAPEFF	CATSPERG	1016	Q6ZRH7
IQQAGCPVPEYIKGF	DDX52	531	Q9Y2R4
SPLFPGKNDIEQLCY	CDK20	201	Q8IZL9
FAGCQIPYPKREFLN	CDK19	346	Q9BWU1
GALIPKVFQQYPESC	BPIFB4	461	P59827
KQIFPFFDIPCQGLY	GOT1L1	206	Q8NHS2
LIYHQTCKVPPFVFF	ALG3	141	Q92685
APRPANFKCNSGYVV	ABCG2	111	Q9UNQ0
AGDQIPKYCFPNYVG	ACTR1B	26	P42025
LCAFAYPNQKDFPST	DPPA4	121	Q7L190
GPFIDSYRCFQPKQE	APEX2	241	Q9UBZ4
RPFYKDVNECKVFPG	FBN3	981	Q75N90
FINYSIQKPCSPFDV	DBF4	241	Q9UBU7
VQTLPPEDFCFYQGS	ADAMTS16	136	Q8TE57
EVYGFRLKNPYQCPF	ADAMTS20	1766	P59510
GAPCVFPFTFLGNKY	MMP2	346	P08253
GVDLGQKPNPYFYSC	RAB24	186	Q969Q5
ICQAKGIGYFFVLQP	ADAMTS1	661	Q9UHI8
FYCEGNPLFLQQPVI	LRRC69	226	Q6ZNQ3
CLEVVTFSYKPPGNF	RBL2	536	Q08999
LPPFIYGRDFKCQNF	ANKAR	356	Q7Z5J8
GNADGKPCQFPFIFQ	MMP9	281	P14780
KPCQFPFIFQGQSYS	MMP9	286	P14780
FYISQLPFCGPNIID	OR11H4	171	Q8NGC9
YGATVFCVAPNAVFP	MCMDC2	626	Q4G0Z9
FCVAPNAVFPFELYN	MCMDC2	631	Q4G0Z9
PSVDYVCQLKFPSGN	LANCL1	246	O43813
NFSYPICEAALPKFS	LY86	96	O95711
FPYLCGNLNDVVVSP	GREB1	391	Q4ZG55
KGYKRCILFPPDQFE	HIF1AN	211	Q9NWT6
DGYPEQFCVRIEKNP	LRRC7	1441	Q96NW7
FGQPSDCQPRAFYLK	LRIG3	1056	Q6UXM1
PFAIFQLPYEKACKN	ITGAE	811	P38570
TQLYKDPCAFQRGPA	PDX1	11	P52945
VQFLFIYQLPFCGPN	OR4A15	186	Q8NGL6
IYQLPFCGPNVIDNF	OR4A15	191	Q8NGL6
AFTVNLPFCGPNKVD	OR4K15	161	Q8NH41
FIYTCPFQAFPADKV	OR4N5	256	Q8IXE1
AFIGYFVEKPPNAAA	PGLYRP3	276	Q96LB9
YAVKGCFRFLPPAQV	NOL6	146	Q9H6R4
IDPNYRFPTCKGFFN	DDHD2	521	O94830
CEEKPNFNFSQPYPE	MYO10	976	Q9HD67
PFVDGKSPLQVYCEA	JAKMIP3	631	Q5VZ66
PLACFLNEPYLQVDF	CLC	26	Q05315
PQCNAEYLIVFPKLG	MARCHF5	66	Q9NX47
INYHSPFGCKFVIPL	EDC3	491	Q96F86
AFVEFSCKPPQYGQL	MON2	1366	Q7Z3U7
GPNQVDYFFCDIPAV	OR10G3	171	Q8NGC4
YFQPGVCFKTVPGVL	PCDHGB3	726	Q9Y5G1
RYQTNPCIGYKLFPN	ITGB5	196	P18084
FLINSNYVDPKFPPC	HOXB4	6	P17483
CYVSQQELKPFPFGV	SMPD2	221	O60906
KPEQVYQFFSCLPED	PRICKLE3	101	O43900
PKLFYKCDQGQADPV	HTT	936	P42858
EVIVKNPCNFPIEFY	HYDIN	1846	Q4G0P3
CYPKITFVPADSDFQ	BSND	56	Q8WZ55
INNYISCFAPGDPKT	DOCK9	1046	Q9BZ29
PLEVFPFGKTVNYTC	CR1	436	P17927
PLEVFPFGKAVNYTC	CR1	886	P17927
EACLKAFKPYQGNPT	DNAH17	3211	Q9UFH2
IPAFYCPDKNKVNFI	FAM117B	491	Q6P1L5
QPFSIPVRALCNGDY	CPNE9	201	Q8IYJ1
KQPGCPNVCYDEFFP	GJB4	56	Q9NTQ9
AGDQIPKYCFPNYVG	ACTR1A	26	P61163
SPPFRAICQEGKFEY	CFHR5	551	Q9BXR6
PYPALAATVFFCLGQ	CACNA1H	71	O95180
FAGCQIPYPKREFLT	CDK8	346	P49336
KIGAYCAQPDFQPDI	DNAH2	3171	Q9P225
PVGTYQPEFGKNNCV	SCUBE2	771	Q9NQ36
PVKPCFYQNFSDEIP	SCAMP4	16	Q969E2
DFPAVTICNASPFKY	SCNN1B	91	P51168
LKDLFCNEEGTYFPP	SACS	1061	Q9NZJ4
NQFKPFIDVFGCQLP	SACS	1616	Q9NZJ4
EHYNPATGKFICAFP	C1QTNF7	176	Q9BXJ2
VFEKLQLFYPECQPE	NUP210L	1286	Q5VU65
PVGKEEFVYIACQGP	PTPN13	2271	Q12923
FNFGQRAEPYCSVLP	HNRNPUL1	381	Q9BUJ2
YTTCFIPGNLPFKLE	PCDHGA1	381	Q9Y5H4
FFPGSTRKSQVCPYN	RP1	1646	P56715
YPVCFGRQKAPVTAG	ITK	336	Q08881
GQIEKQPPFEIYLCF	IRF6	361	O14896
FQIVVYSLPFCGPNV	OR4A5	156	Q8NH83
FQILVVYSLPFCGPN	OR4A8	156	P0C604
QGERKPPKVFAFDYC	KIF13A	46	Q9H1H9
NCPGATPELFKYFSQ	FBXL16	456	Q8N461
VPCVFPFIFNGKSYE	IGF2R	1901	P11717
LNGVTVDFPFQPYKC	RTEL1	6	Q9NZ71
ANKYVYFVCNEPGRP	RSPH4A	426	Q5TD94
QEYPLIKNCFTPQTG	MEIOC	261	A2RUB1
VVQFPCSDRFKPSYV	RPE65	226	Q16518
ALIFAIQKCDPAPFY	SMC3	1126	Q9UQE7
IQKCDPAPFYLFDEI	SMC3	1131	Q9UQE7
KFSGAPNLPVYVVDC	SMCHD1	971	A6NHR9
KDGDIFNPACLPIYQ	PLCD4	276	Q9BRC7
KCQGLFAPQFYVQPD	SKIL	271	P12757
KNDDGVIPCQNKYPF	TEC	66	P42680
YICDQPTGGIFNPAK	RNF113B	291	Q8IZP6
ANYFLNFPCKVGTTP	NBEAL2	1996	Q6ZNJ1
QGFYVCPVEPQNRSK	PSAT1	286	Q9Y617
PRCITKFAQYVGSFP	SH2D5	21	Q6ZV89
FCKPPSVQAQANFLY	SKIDA1	471	Q1XH10
IPCPLTLNYVEKGFQ	SLC38A6	216	Q8IZM9
QKGIQCAAQTYPGPF	SLCO5A1	811	Q9H2Y9
IYPGQFQPSLCHKFI	SIRT1	316	Q96EB6
FLKAEELCPGYSNPN	RMDN2	346	Q96LZ7
IKCVIPGSDPFLEYN	PLA2G1B	31	P04054
QYKFFIVACDPPQKS	RNASE6	121	Q93091
QSFQEALAIYPPCGR	TEAD2	51	Q15562
KIFRCPSPIYFANIG	SLC26A3	536	P40879
PIFYFFEKNVQGSIP	SGMS2	316	Q8NHU3
PVGNDLAFECKGQFY	SERTAD4	301	Q9NUC0
FQLCKTVRHGFPYQP	STXBP5	46	Q5T5C0
GKVDFTDPCNYQLIP	NUP160	191	Q12769
FPFGSKQKEVCINPY	SMAD1	111	Q15797
QKGPVYVACQFPISL	ATP1B3	136	P54709
CPQEDYFPPNLFVKV	PIAS3	201	Q9Y6X2
YFPPNLFVKVNGKLC	PIAS3	206	Q9Y6X2
FCYFGQPLIDPQETV	ZFHX4	3376	Q86UP3
VLQASQAGPPFFCYT	ZFP57	81	Q9NU63
QPQCPAVFYTFNKLK	RLF	1411	Q13129
LGTCYQVEPNTKVFP	RYR3	1431	Q15413
QSFQEALAIYPPCGR	TEAD3	41	Q99594
NTVYFTCRAEGNPKP	PXDN	261	Q92626
QAGIVFPDCFYPSIC	GPLD1	61	P80108
PPQIANFEEGFVVKY	PKHD1L1	671	Q86WI1
IFGFQACQYKPLPDC	TMEM171	41	Q8WVE6
SFLPDPYQKQCDQFV	PSAP	441	P07602
ITYKNFGDQPDIRCP	SF3B3	256	Q15393
AQKSYGNEKRFFCPP	RBPJ	56	Q06330
YFNLISVGCQVPKPE	ZNF484	41	Q5JVG2
QKFQPPFFTLDVECG	TRUB1	236	Q8WWH5
PKCDYGTNVPVEFRN	ZNF407	1776	Q9C0G0
QSFQEALAIYPPCGR	TEAD1	41	P28347
GCKLYFFQSLPPENV	YIPF2	276	Q9BWQ6
SYNALQCIPPLAFQG	SLIT1	816	O75093
CVQSPLANTPFLGYF	TCTN2	236	Q96GX1
ASNPFPYKAAVCFAE	ZNF518B	501	Q9C0D4
VSVCPQSLPYFAAKF	NARF	96	Q9UHQ1