Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT1A5 INSR AKR1C1 AKR1C2 UGT1A4 UGT1A3

1.63e-051071006GO:0033293
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C1 AKR1C2

1.48e-0441002GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C1 AKR1C2

1.48e-0441002GO:0045703
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

1.48e-0441002GO:0047718
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C1 AKR1C2

1.48e-0441002GO:0047743
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C1 AKR1C2

2.46e-0451002GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C1 AKR1C2

2.46e-0451002GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C1 AKR1C2

2.46e-0451002GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C1 AKR1C2

2.46e-0451002GO:0047006
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C1 AKR1C2

2.46e-0451002GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C1 AKR1C2

2.46e-0451002GO:0047086
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C1 AKR1C2

2.46e-0451002GO:0047787
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A5 UGT1A4 UGT1A3

3.65e-04281003GO:0001972
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C1 AKR1C2

3.68e-0461002GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C1 AKR1C2

5.13e-0471002GO:0072582
GeneOntologyMolecularFunctioniron-sulfur cluster binding

LIAS AOX1 IREB2 NUBP1

6.36e-04781004GO:0051536
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C1 AKR1C2

6.82e-0481002GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C1 AKR1C2

6.82e-0481002GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C1 AKR1C2

6.82e-0481002GO:0035671
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A5 UGT1A4 UGT1A3

7.10e-04351003GO:0015020
GeneOntologyMolecularFunctionmetal cluster binding

LIAS AOX1 IREB2 NUBP1

8.04e-04831004GO:0051540
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C1 AKR1C2

8.74e-0491002GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C1 AKR1C2

8.74e-0491002GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C1 AKR1C2

1.09e-03101002GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C1 AKR1C2

1.09e-03101002GO:0032052
GeneOntologyMolecularFunctioncarboxylic acid binding

UGT1A5 INSR AKR1C1 AKR1C2 UGT1A4 UGT1A3

1.29e-032391006GO:0031406
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

LIAS IREB2 NUBP1

1.68e-03471003GO:0051539
GeneOntologyMolecularFunctionorganic acid binding

UGT1A5 INSR AKR1C1 AKR1C2 UGT1A4 UGT1A3

1.76e-032541006GO:0043177
GeneOntologyMolecularFunctionretinoid binding

UGT1A5 UGT1A4 UGT1A3

1.79e-03481003GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A5 UGT1A4 UGT1A3

1.90e-03491003GO:0019840
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C1 AKR1C2

2.17e-03141002GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C1 AKR1C2

2.17e-03141002GO:0001758
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AOX1 AKR1C1 AKR1C2

2.79e-03561003GO:0016903
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT1A5 UGT1A4 UGT1A3 GALNT8 TNKS ALG12

3.28e-032881006GO:0016757
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C1 AKR1C2 ACAD11

3.72e-03621003GO:0016627
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A5 UGT1A4 UGT1A3 GALNT8 ALG12

4.20e-032111005GO:0016758
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C2

4.45e-03201002GO:0004303
GeneOntologyBiologicalProcessresponse to prostaglandin D

PTGFR AKR1C1 AKR1C2

3.70e-067993GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

PTGFR AKR1C1 AKR1C2

3.70e-067993GO:0071799
GeneOntologyBiologicalProcessoxoacid metabolic process

LIAS GALE CES1 UGT1A5 INSR IREB2 ACOT6 PTGIS ANKH AKR1C1 AKR1C2 TXNRD1 UGT1A4 UGT1A3 ACAD11 ASS1 AHCY

1.07e-0510589917GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

LIAS GALE CES1 UGT1A5 INSR IREB2 ACOT6 PTGIS ANKH AKR1C1 AKR1C2 TXNRD1 UGT1A4 UGT1A3 ACAD11 ASS1 AHCY

1.15e-0510649917GO:0006082
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SEMA4F DIP2B SLC11A2 WNT7A CDH23 SPG11 PLXNB2 GDNF SPTBN4 PTPRD CELSR3 CELSR2 MEGF8 CNTN2

1.32e-057489914GO:0048667
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

LIAS GALE CES1 UGT1A5 INSR IREB2 ACOT6 PTGIS AKR1C1 AKR1C2 TXNRD1 UGT1A4 UGT1A3 ACAD11 ASS1 AHCY

3.21e-0510359916GO:0019752
GeneOntologyBiologicalProcesscell morphogenesis

SEMA4F DIP2B SLC11A2 WNT7A SLC26A5 CDH23 SPG11 PLXNB2 GDNF SPTBN4 PTPRD CELSR3 CELSR2 MEGF8 IHH CNTN2 EPB42

4.99e-0511949917GO:0000902
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

ACER2 MYADM ABCA12 DUSP1 ACP5 PLXNB2 BTN2A1 ASS1 IHH

8.09e-05375999GO:0007162
GeneOntologyBiologicalProcessneuron projection morphogenesis

SEMA4F DIP2B SLC11A2 WNT7A SPG11 PLXNB2 GDNF SPTBN4 PTPRD CELSR3 CELSR2 MEGF8 CNTN2

1.19e-048029913GO:0048812
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

MYADM CDH23 PLXNB2 TENM4 PTPRD CELSR3 CELSR2 CNTN2

1.33e-04313998GO:0098742
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A5 UGT1A4 UGT1A3

1.34e-0421993GO:0052695
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C1 AKR1C2

1.36e-044992GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C1 AKR1C2

1.36e-044992GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C1 AKR1C2

1.36e-044992GO:0071395
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C1 AKR1C2

1.36e-044992GO:0008208
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

SEMA4F DIP2B SLC11A2 WNT7A SPG11 PLXNB2 GDNF SPTBN4 PTPRD CELSR3 CELSR2 MEGF8 CNTN2

1.47e-048199913GO:0120039
GeneOntologyBiologicalProcessparturition

PTGFR AKR1C1 AKR1C2

1.55e-0422993GO:0007567
GeneOntologyBiologicalProcessembryonic morphogenesis

LIAS MYADM DUSP1 WNT7A CDH23 PLXNB2 GDNF TXNRD1 TENM4 MEGF8 IHH EXOC4

1.57e-047139912GO:0048598
GeneOntologyBiologicalProcesscell projection morphogenesis

SEMA4F DIP2B SLC11A2 WNT7A SPG11 PLXNB2 GDNF SPTBN4 PTPRD CELSR3 CELSR2 MEGF8 CNTN2

1.59e-048269913GO:0048858
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

PTGFR AKR1C1 AKR1C2

1.77e-0423993GO:0071379
GeneOntologyBiologicalProcessneuron development

SEMA4F DIP2B SLC11A2 WNT7A CDH23 MPDZ SPG11 PLXNB2 GDNF NCDN SPTBN4 TENM4 PTPRD CELSR3 CELSR2 MEGF8 IHH CNTN2

1.88e-0414639918GO:0048666
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

LIAS GALE CES1 UGT1A5 INSR ACOT6 PTGIS AKR1C1 AKR1C2 UGT1A4 UGT1A3 ACAD11

1.97e-047319912GO:0032787
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C1 AKR1C2

2.26e-045992GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C1 AKR1C2

2.26e-045992GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C1 AKR1C2

2.26e-045992GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C1 AKR1C2

2.26e-045992GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C1 AKR1C2

2.26e-045992GO:0120256
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2

2.26e-045992GO:1900053
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

IREB2 GDNF AKR1C1 AKR1C2 SYNCRIP

2.33e-04115995GO:1903312
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A5 UGT1A4 UGT1A3

2.57e-0426993GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A5 UGT1A4 UGT1A3

2.57e-0426993GO:0006063
GeneOntologyBiologicalProcessneuron projection fasciculation

CELSR3 MEGF8 CNTN2

3.22e-0428993GO:0106030
GeneOntologyBiologicalProcessaxonal fasciculation

CELSR3 MEGF8 CNTN2

3.22e-0428993GO:0007413
GeneOntologyBiologicalProcessregulation of axonogenesis

SEMA4F DIP2B WNT7A PLXNB2 MEGF8 CNTN2

3.29e-04192996GO:0050770
GeneOntologyBiologicalProcessregulation of axon diameter

WNT7A CNTN2

3.38e-046992GO:0031133
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C1 AKR1C2

3.38e-046992GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C1 AKR1C2

3.38e-046992GO:0016095
GeneOntologyBiologicalProcesspolyprenol metabolic process

AKR1C1 AKR1C2 ALG12

3.58e-0429993GO:0016093
GeneOntologyBiologicalProcessaxonogenesis

SEMA4F DIP2B WNT7A SPG11 PLXNB2 GDNF SPTBN4 CELSR3 MEGF8 CNTN2

3.90e-045669910GO:0007409
GeneOntologyBiologicalProcessneuron projection development

SEMA4F DIP2B SLC11A2 WNT7A CDH23 MPDZ SPG11 PLXNB2 GDNF NCDN SPTBN4 PTPRD CELSR3 CELSR2 MEGF8 CNTN2

3.93e-0412859916GO:0031175
GeneOntologyBiologicalProcesscellular response to ketone

PTGFR GDNF AKR1C1 AKR1C2 ASS1

4.10e-04130995GO:1901655
GeneOntologyBiologicalProcesscellular response to alcohol

CES1 IREB2 PTGFR AKR1C1 AKR1C2

4.10e-04130995GO:0097306
GeneOntologyBiologicalProcessvitamin metabolic process

AKR1C1 AKR1C2 UGT1A4 UGT1A3 SLC52A2

4.55e-04133995GO:0006766
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2

4.71e-047992GO:1900052
GeneOntologyBiologicalProcessmulticellular organismal-level iron ion homeostasis

SLC11A2 IREB2 EPB42

4.81e-0432993GO:0060586
GeneOntologyBiologicalProcesscholesterol efflux

CES1 ABCA12 SPG11 SOAT1

5.17e-0477994GO:0033344
GeneOntologyBiologicalProcessgastrulation

MYADM DUSP1 TXNRD1 TENM4 MEGF8 EXOC4

5.56e-04212996GO:0007369
GeneOntologyBiologicalProcesscellular response to corticosteroid stimulus

GDNF AKR1C1 AKR1C2 ASS1

6.26e-0481994GO:0071384
GeneOntologyBiologicalProcessresponse to prostaglandin

PTGFR AKR1C1 AKR1C2

6.83e-0436993GO:0034694
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C1 AKR1C2

8.03e-049992GO:0044597
GeneOntologyBiologicalProcessvitamin D3 metabolic process

UGT1A4 UGT1A3

8.03e-049992GO:0070640
GeneOntologyBiologicalProcessalcohol metabolic process

ACER2 CES1 AKR1C1 AKR1C2 UGT1A4 UGT1A3 ALG12 SOAT1

8.32e-04412998GO:0006066
GeneOntologyBiologicalProcessmulticellular organismal-level chemical homeostasis

SLC11A2 ABCA12 IREB2 EPB42

9.30e-0490994GO:0140962
GeneOntologyBiologicalProcessretinoic acid metabolic process

AKR1C1 AKR1C2 UGT1A3

9.32e-0440993GO:0042573
GeneOntologyBiologicalProcessskeletal muscle satellite cell activation

WNT7A GJD4

1.00e-0310992GO:0014719
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C1 AKR1C2

1.00e-0310992GO:0044598
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C1 AKR1C2

1.00e-0310992GO:0019747
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C1 AKR1C2

1.00e-0310992GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C1 AKR1C2

1.00e-0310992GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C1 AKR1C2

1.00e-0310992GO:0030647
GeneOntologyBiologicalProcessaxon development

SEMA4F DIP2B WNT7A SPG11 PLXNB2 GDNF SPTBN4 CELSR3 MEGF8 CNTN2

1.03e-036429910GO:0061564
GeneOntologyBiologicalProcessregulation of cellular component size

SEMA4F DIP2B MYADM WNT7A SLC26A5 SPTBN4 MEGF8 CNTN2

1.03e-03426998GO:0032535
GeneOntologyBiologicalProcesscellular response to fatty acid

AKR1C1 AKR1C2 ASS1

1.07e-0342993GO:0071398
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C1 AKR1C2

1.22e-0311992GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C1 AKR1C2

1.22e-0311992GO:0016115
GeneOntologyBiologicalProcessregulation of nitric oxide biosynthetic process

ACP5 INSR PTGIS ASS1

1.23e-0397994GO:0045428
GeneOntologyBiologicalProcessbone resorption

ACP5 LRRK1 NCDN IHH

1.33e-0399994GO:0045453
GeneOntologyBiologicalProcessregulation of nitric oxide metabolic process

ACP5 INSR PTGIS ASS1

1.38e-03100994GO:0080164
GeneOntologyBiologicalProcessexcitatory synapse assembly

WNT7A PLXNB2 PTPRD

1.40e-0346993GO:1904861
GeneOntologyBiologicalProcessmulticellular organismal-level homeostasis

SLC11A2 CES1 ABCA12 ACP5 CDH23 IREB2 LRRK1 ANKH NCDN SLC35D3 IHH CNTN2 EPB42

1.43e-0310439913GO:0048871
MousePhenoparturition failure

PTGFR AKR1C1 AKR1C2

1.73e-0510753MP:0012010
MousePhenoclub-shaped femur

ACP5 ANKH

2.84e-052752MP:0030791
MousePhenoabnormal cerebellar granule cell migration

MARVELD1 PLXNB2 ASS1

5.17e-0514753MP:0009977
MousePhenoincreased bone mineral content

MYH2 CDH23 LRRK1 ANKH TENM4 PTPRD WNT10A SYNCRIP

7.00e-05258758MP:0010123
MousePhenoabnormal gait

MARVELD1 WNT7A CDH23 IREB2 SPG11 LRRK1 ANKH AKR1C1 AKR1C2 SPTBN4 ASS1

9.62e-055207511MP:0001406
MousePhenoabnormal oligodendrocyte morphology

IREB2 AKR1C1 AKR1C2 TENM4

1.58e-0451754MP:0000953
MousePhenodistended duodenum

GDNF CELSR3

1.69e-044752MP:0011881
DomainPlexin_repeat

SEMA4F PLXDC1 PLXNB2 MEGF8

2.48e-05321004IPR002165
DomainPSI

SEMA4F PLXDC1 PLXNB2 MEGF8

2.48e-05321004PF01437
DomainPSI

SEMA4F PLXDC1 PLXNB2 MEGF8

1.06e-04461004SM00423
DomainUDPGT

UGT1A5 UGT1A4 UGT1A3

1.85e-04211003PF00201
DomainUDPGT

UGT1A5 UGT1A4 UGT1A3

1.85e-04211003PS00375
DomainUDP_glucos_trans

UGT1A5 UGT1A4 UGT1A3

1.85e-04211003IPR002213
DomainYIPPEE

YPEL2 YPEL1

2.81e-0451002PS51792
Domain-

PPP1R12A LRRK1 ANKRD44 TRANK1 ASB16 TNKS TRPV5

3.75e-0424810071.25.40.20
DomainANK

PPP1R12A LRRK1 ANKRD44 TRANK1 ASB16 TNKS TRPV5

4.03e-042511007SM00248
DomainANK_REPEAT

PPP1R12A LRRK1 ANKRD44 TRANK1 ASB16 TNKS TRPV5

4.23e-042531007PS50088
DomainAnkyrin_rpt-contain_dom

PPP1R12A LRRK1 ANKRD44 TRANK1 ASB16 TNKS TRPV5

4.33e-042541007IPR020683
DomainANK_REP_REGION

PPP1R12A LRRK1 ANKRD44 TRANK1 ASB16 TNKS TRPV5

4.33e-042541007PS50297
DomainAnkyrin_rpt

PPP1R12A LRRK1 ANKRD44 TRANK1 ASB16 TNKS TRPV5

5.21e-042621007IPR002110
DomainEGF_LAM_2

CELSR3 CELSR2 MEGF8

5.44e-04301003PS50027
DomainEGF_LAM_1

CELSR3 CELSR2 MEGF8

5.44e-04301003PS01248
DomainYippee/Mis18/Cereblon

YPEL2 YPEL1

7.78e-0481002IPR004910
DomainYippee-Mis18

YPEL2 YPEL1

7.78e-0481002PF03226
DomainEGF_Lam

CELSR3 CELSR2 MEGF8

8.61e-04351003SM00180
DomainLaminin_EGF

CELSR3 CELSR2 MEGF8

8.61e-04351003PF00053
DomainAnk_2

PPP1R12A LRRK1 ANKRD44 ASB16 TNKS TRPV5

1.05e-032151006PF12796
DomainLaminin_EGF

CELSR3 CELSR2 MEGF8

1.10e-03381003IPR002049
DomainConA-like_dom

MAMDC4 BTN2A1 CELSR3 CELSR2 COL21A1 SEL1L3

1.16e-032191006IPR013320
DomainALDOKETO_REDUCTASE_1

AKR1C1 AKR1C2

1.24e-03101002PS00798
DomainALDOKETO_REDUCTASE_2

AKR1C1 AKR1C2

1.24e-03101002PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C1 AKR1C2

1.24e-03101002PS00063
DomainAldo/ket_reductase_CS

AKR1C1 AKR1C2

1.24e-03101002IPR018170
DomainAldo/keto_reductase

AKR1C1 AKR1C2

1.24e-03101002IPR020471
DomainAnk

PPP1R12A LRRK1 ANKRD44 ASB16 TNKS TRPV5

1.42e-032281006PF00023
DomainGAIN_dom_N

CELSR3 CELSR2

1.51e-03111002IPR032471
DomainGAIN

CELSR3 CELSR2

1.51e-03111002PF16489
DomainPSI

SEMA4F PLXNB2 MEGF8

1.68e-03441003IPR016201
Domain-

AKR1C1 AKR1C2

3.24e-031610023.20.20.100
DomainNADP_OxRdtase_dom

AKR1C1 AKR1C2

3.66e-03171002IPR023210
DomainAldo_ket_red

AKR1C1 AKR1C2

3.66e-03171002PF00248
DomainAldo/ket_red/Kv-b

AKR1C1 AKR1C2

3.66e-03171002IPR001395
DomainLaminin_G

CELSR3 CELSR2 COL21A1

3.71e-03581003IPR001791
DomainWnt

WNT7A WNT10A

4.57e-03191002IPR005817
DomainWNT1

WNT7A WNT10A

4.57e-03191002PS00246
DomainWnt_CS

WNT7A WNT10A

4.57e-03191002IPR018161
Domainwnt

WNT7A WNT10A

4.57e-03191002PF00110
DomainWNT1

WNT7A WNT10A

4.57e-03191002SM00097
PathwayREACTOME_PREDNISONE_ADME

UGT1A5 AKR1C1 AKR1C2 UGT1A4 UGT1A3

1.24e-0723765MM16639
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A5 AKR1C1 AKR1C2 UGT1A4 UGT1A3

1.12e-0555765M14933
PathwayWP_FERROPTOSIS

SLC11A2 IREB2 AKR1C1 AKR1C2 TXNRD1

2.37e-0564765M39768
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A5 AKR1C1 AKR1C2 UGT1A4 UGT1A3

3.67e-0570765M16794
PathwayREACTOME_DRUG_ADME

CES1 UGT1A5 AKR1C1 AKR1C2 UGT1A4 UGT1A3

4.31e-05119766MM15692
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

PTGIS AKR1C1 AKR1C2

6.54e-0515763MM14870
PathwayREACTOME_ATORVASTATIN_ADME

UGT1A5 UGT1A4 UGT1A3

6.54e-0515763MM15697
PathwayREACTOME_ASPIRIN_ADME

CES1 UGT1A5 UGT1A4 UGT1A3

8.99e-0544764M45014
PathwayWP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION

PTGFR PTGIS AKR1C1 AKR1C2

9.83e-0545764M39355
PathwayREACTOME_ASPIRIN_ADME

CES1 UGT1A5 UGT1A4 UGT1A3

9.83e-0545764MM15694
PathwayREACTOME_HEME_DEGRADATION

UGT1A5 UGT1A4 UGT1A3

1.61e-0420763MM14721
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

CES1 UGT1A5 UGT1A4 UGT1A3

1.61e-0451764M17726
PathwayREACTOME_GLUCURONIDATION

UGT1A5 UGT1A4 UGT1A3

2.81e-0424763MM14599
PathwayREACTOME_DRUG_ADME

CES1 UGT1A5 AKR1C1 UGT1A4 UGT1A3

3.01e-04109765M45012
PathwayREACTOME_GLUCURONIDATION

UGT1A5 UGT1A4 UGT1A3

3.18e-0425763M17787
PathwayWP_GLUCURONIDATION

UGT1A5 UGT1A4 UGT1A3

3.18e-0425763MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A5 UGT1A4 UGT1A3

3.18e-0425763M605
PathwayWP_GLUCURONIDATION

UGT1A5 UGT1A4 UGT1A3

3.58e-0426763M39404
PathwayWP_NICOTINE_METABOLISM_IN_LIVER_CELLS

AOX1 UGT1A4

4.24e-046762M39600
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A5 UGT1A4 UGT1A3

4.48e-0428763M19580
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

ACP5 AOX1 PTGIS AKR1C1 AKR1C2 SLC52A2

5.39e-04189766MM14772
PathwayREACTOME_VITAMIN_B2_RIBOFLAVIN_METABOLISM

ACP5 SLC52A2

5.92e-047762M27092
PathwayREACTOME_VITAMIN_B2_RIBOFLAVIN_METABOLISM

ACP5 SLC52A2

5.92e-047762MM14770
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A5 AOX1 UGT1A4 UGT1A3

6.08e-0472764M9257
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

UGT1A5 UGT1A4 UGT1A3

6.67e-0432763MM14719
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C1 AKR1C2

1.01e-039762M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C1 AKR1C2

1.01e-039762M47817
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CES1 UGT1A5 PTGIS UGT1A4 UGT1A3 AHCY

1.16e-03219766MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CES1 UGT1A5 PTGIS UGT1A4 UGT1A3 AHCY

1.19e-03220766M10320
PathwayREACTOME_PREDNISONE_ADME

AKR1C1 UGT1A3

1.26e-0310762M46430
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A5 UGT1A4 UGT1A3

1.39e-0341763M7399
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C1 AKR1C2

1.53e-0311762M47812
PathwayWP_IRON_METABOLISM_IN_PLACENTA

SLC11A2 IREB2

1.83e-0312762M39660
Pubmed

Discovery and refinement of loci associated with lipid levels.

UGT1A5 INSR R3HDM2 UGT1A4 UGT1A3 ACAD11 CELSR2 DOCK6

2.33e-07211103824097068
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A5 UGT1A4 UGT1A3 ACAD11

2.72e-0719103423281178
Pubmed

Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping.

MPDZ GDNF PTPRD

8.75e-077103317619104
Pubmed

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.

PPP1R12A DUSP1 AKR1C1 AKR1C2

1.41e-0628103420689807
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

CELSR3 CELSR2 MEGF8

2.09e-06910339693030
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A5 UGT1A4 UGT1A3

2.09e-069103322511988
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A5 UGT1A4 UGT1A3

2.09e-06910331339448
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A5 UGT1A4 UGT1A3

2.98e-0610103323642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A5 UGT1A4 UGT1A3

2.98e-0610103311465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A5 UGT1A4 UGT1A3

2.98e-0610103323371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A5 UGT1A4 UGT1A3

2.98e-0610103322558097
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A5 UGT1A4 UGT1A3

5.44e-0612103319419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A5 UGT1A4 UGT1A3

5.44e-0612103311434514
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A5 UGT1A4 UGT1A3

7.06e-0613103322085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A5 UGT1A4 UGT1A3

7.06e-0613103325246029
Pubmed

Regulatory effects of genomic translocations at the human carboxylesterase-1 (CES1) gene locus.

CES1P1 CES1

8.69e-062103226871237
Pubmed

Identification of pp68 as the Tyrosine-phosphorylated Form of SYNCRIP/NSAP1. A cytoplasmic RNA-binding protein.

INSR SYNCRIP

8.69e-062103211994298
Pubmed

Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.

AKR1C1 AKR1C2

8.69e-06210328573067
Pubmed

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.

AKR1C1 AKR1C2

8.69e-062103211514561
Pubmed

Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

UGT1A5 UGT1A3

8.69e-06210328068691
Pubmed

Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling.

AKR1C1 AKR1C2

8.69e-062103215492289
Pubmed

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.

UGT1A4 UGT1A3

8.69e-062103224641623
Pubmed

Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on chromosome 9.

CELSR3 CELSR2

8.69e-062103210790539
Pubmed

cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase.

AKR1C1 AKR1C2

8.69e-06210328011662
Pubmed

Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors.

AKR1C1 AKR1C2

8.69e-062103218654764
Pubmed

Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses.

AKR1C1 AKR1C2

8.69e-062103221217827
Pubmed

The roles of AKR1C1 and AKR1C2 in ethyl-3,4-dihydroxybenzoate induced esophageal squamous cell carcinoma cell death.

AKR1C1 AKR1C2

8.69e-062103226934124
Pubmed

Human carboxylesterase 1A2 expressed from carboxylesterase 1A1 and 1A2 genes is a potent predictor of CPT-11 cytotoxicity in vitro.

CES1P1 CES1

8.69e-062103217264798
Pubmed

cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.

AKR1C1 AKR1C2

8.69e-06210328486699
Pubmed

Zinc induces iron uptake and DMT1 expression in Caco-2 cells via a PI3K/IRP2 dependent mechanism.

SLC11A2 IREB2

8.69e-062103231092704
Pubmed

N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases.

UGT1A4 UGT1A3

8.69e-062103214570768
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A5 UGT1A4 UGT1A3

8.97e-0614103321646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A5 UGT1A4 UGT1A3

8.97e-0614103310836148
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A5 UGT1A4 UGT1A3

8.97e-0614103314672974
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A5 UGT1A4 UGT1A3

8.97e-061410339295054
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

SEMA4F INSR GDNF PTPRD CELSR3 CELSR2 IHH

1.03e-05251103729031500
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

WNT7A CELSR3 CELSR2 WNT10A

1.17e-0547103433141892
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A5 UGT1A4 UGT1A3

1.37e-0516103319414484
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A5 UGT1A4 UGT1A3

1.66e-0517103320639394
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CDH23 SPG11 ARMC9 LRRK1 GMPPB

1.73e-05107103511347906
Pubmed

Foxl2 functions in sex determination and histogenesis throughout mouse ovary development.

GDNF AKR1C1 AKR1C2 TENM4

2.20e-0555103419538736
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C1 AKR1C2

2.60e-053103219320734
Pubmed

Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum.

SLC11A2 IREB2

2.60e-053103218177727
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C1 AKR1C2

2.60e-053103231780644
Pubmed

Genetic variation in carboxylesterase genes and susceptibility to isoniazid-induced hepatotoxicity.

CES1P1 CES1

2.60e-053103220195289
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C1 AKR1C2

2.60e-053103221232532
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C1 AKR1C2

2.60e-053103213678667
Pubmed

Interleukin 1β regulates progesterone metabolism in human cervical fibroblasts.

AKR1C1 AKR1C2

2.60e-053103222064385
Pubmed

Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.

UGT1A5 UGT1A3

2.60e-053103212051676
Pubmed

Human carboxylesterases in term placentae: enzymatic characterization, molecular cloning and evidence for the existence of multiple forms.

CES1P1 CES1

2.60e-053103210452915
Pubmed

The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.

CELSR3 CELSR2

2.60e-053103211677057
Pubmed

Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4.

UGT1A4 UGT1A3

2.60e-053103223611809
Pubmed

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells.

PTGFR AKR1C2

2.60e-053103218508192
Pubmed

A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules.

UGT1A5 UGT1A3

2.60e-053103221383159
Pubmed

Plexin-B2 controls the development of cerebellar granule cells.

SEMA4F PLXNB2 CNTN2

3.23e-0521103317409257
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DIP2B POLR1A PPP1R12A INSR ANKH NCDN SGK2 SPTBN4 ANKRD44 PCNX4 ASS1 SEL1L3 DOCK6 ALG12 EXOC4

3.28e-0514891031528611215
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT1A5 AOX1 UGT1A4 UGT1A3

4.54e-0566103419898482
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A5 UGT1A4 UGT1A3

4.88e-0524103324625756
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C1 AKR1C2

5.19e-054103220124700
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C1 AKR1C2

5.19e-054103210500239
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C1 AKR1C2

5.19e-054103216508162
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C1 AKR1C2

5.19e-054103219487289
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2

5.19e-054103214967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C1 AKR1C2

5.19e-054103210393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C1 AKR1C2

5.19e-054103215193432
Pubmed

Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.

UGT1A5 UGT1A4

5.19e-054103218223459
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C1 AKR1C2

5.19e-054103231479646
Pubmed

A high-resolution genetic, physical, and comparative gene map of the doublefoot (Dbf) region of mouse chromosome 1 and the region of conserved synteny on human chromosome 2q35.

WNT10A IHH

5.19e-054103211735226
Pubmed

Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1.

MPDZ PTPRD

5.19e-054103220633051
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2

5.19e-054103215222881
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C1 AKR1C2

5.19e-054103216191478
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C1 AKR1C2

5.19e-054103215577209
Pubmed

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.

UGT1A5 UGT1A3

5.19e-054103212644700
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C1 AKR1C2

5.19e-054103210702227
Pubmed

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.

SLC11A2 IREB2

5.19e-054103228714470
Pubmed

Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8.

UGT1A4 UGT1A3

5.19e-05410329535849
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C1 AKR1C2

5.19e-054103217034817
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C1 AKR1C2

5.19e-054103217629694
Pubmed

The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.

CELSR3 CELSR2

5.19e-054103237224017
Pubmed

Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue.

UGT1A4 UGT1A3

5.19e-05410329271343
Pubmed

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice.

SLC11A2 IREB2

5.19e-054103211175792
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C1 AKR1C2

5.19e-054103229764944
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C1 AKR1C2

5.19e-054103210526179
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C1 AKR1C2

5.19e-054103217888864
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C1 AKR1C2

5.19e-054103217442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C1 AKR1C2

5.19e-054103228329705
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C1 AKR1C2

5.19e-054103216018803
Pubmed

Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes.

CES1P1 CES1

5.19e-054103218794728
Pubmed

Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.

SLC26A5 CDH23

5.19e-054103235100259
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2

5.19e-054103217272929
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C1 AKR1C2

5.19e-054103219237748
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C1 AKR1C2

5.19e-054103218667791
Pubmed

Developmental expression profiles of Celsr (Flamingo) genes in the mouse.

CELSR3 CELSR2

5.19e-054103211850187
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C1 AKR1C2

5.19e-054103228259989
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C1 AKR1C2

5.19e-054103221521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2

5.19e-05410328274401
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2

5.19e-054103216511129
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C1 AKR1C2

5.19e-054103210803568
Pubmed

Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.

MYH2 DUSP1

5.19e-054103218417546
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C1 AKR1C2

5.19e-054103234590152
Cytoband2q37

UGT1A5 UGT1A4 UGT1A3

4.85e-053110432q37
Cytoband10p15-p14

AKR1C1 AKR1C2

7.58e-056104210p15-p14
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR3 CELSR2

3.69e-053642913
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR3 CELSR2

3.69e-0536421189
GeneFamilyYippee like family

YPEL2 YPEL1

1.23e-0456421130
GeneFamilyUDP glucuronosyltransferases

UGT1A5 UGT1A4 UGT1A3

1.95e-0432643363
GeneFamilyAnkyrin repeat domain containing

PPP1R12A ANKRD44 TRANK1 ASB16 TNKS TRPV5

2.12e-04242646403
GeneFamilyAldo-keto reductases

AKR1C1 AKR1C2

1.26e-0315642399
GeneFamilyWnt family|Endogenous ligands

WNT7A WNT10A

2.03e-0319642360
CoexpressionGSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP

SLC11A2 ACP5 INSR TMEM167B ZYG11B ANKRD44 TENM4

1.45e-052001037M6019
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

MYADM SLC11A2 MARVELD1 DRAM1 DUSP1 ARMC9 PLXNB2 GDNF ANKH SLC52A2 ALG12 SOAT1

1.52e-0568110312M5314
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

MYADM SLC11A2 MARVELD1 DRAM1 DUSP1 ARMC9 PLXNB2 GDNF ANKH SLC52A2 ALG12 SOAT1

2.08e-0570310312MM1055
ToppCellControl-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

DRAM1 DUSP1 AOX1 PTGIS AKR1C1 AKR1C2 EMP3 SOAT1

1.95e-08197103864cc5f61c88e9560b0f8f6f3151255dffb5c3d66
ToppCelldroplet-Marrow-nan-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYADM CTSC NUBP1 PLXNB2 ASS1 AHCY SOAT1

3.02e-071901037e2fdbfaf08da3274b6bdda615386aa880040a90a
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

GALE CTSC INSR PTGFR AKR1C1 ASS1 SEL1L3

3.72e-071961037057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

GALE CTSC INSR PTGFR AKR1C1 ASS1 SEL1L3

3.85e-0719710373f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

AOX1 SLC5A9 PTGIS AKR1C1 AKR1C2 TXNRD1

4.04e-0618110362b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYADM CES1 PPP1R12A GDNF COL21A1 EMP3

4.17e-061821036728a2152c166551ac229370c0900fe2bc426ea9b
ToppCelldroplet-Marrow-BM-30m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC NUBP1 PLXNB2 ASS1 AHCY SOAT1

4.72e-061861036bcb3ac9f9b51346e0a2b0bda96d149b3c11f7883
ToppCelldroplet-Marrow-nan-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYADM CTSC PLXNB2 ASS1 AHCY SOAT1

5.33e-06190103695d8dc8488e95158e84a44bb53ea4ab7bf3d44bb
ToppCellIPF-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

CTSC INSR AKR1C1 AKR1C2 ASS1 SEL1L3

5.50e-061911036267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

AOX1 PTGIS AKR1C1 AKR1C2 TXNRD1 ANKRD44

6.19e-0619510366a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MYADM MARVELD1 PLXDC1 PTGIS AKR1C2 PTPRD

6.37e-06196103624d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellcritical-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GALE CTSC AKR1C1 AKR1C2 ASS1 SEL1L3

6.37e-061961036dbf14f5851c2b779a8b35e820c4584ea9096e49d
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

AOX1 PTGIS AKR1C1 AKR1C2 TXNRD1 ANKRD44

6.37e-061961036e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellPSB-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GALE CTSC AKR1C1 AKR1C2 ASS1 SEL1L3

6.75e-061981036e4cbe4032dba0da3fd46817ea9ad86ba9217f747
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKR1C1 AKR1C2 BTN2A1 TENM4 ASS1 DOCK6

6.95e-0619910366f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKR1C1 AKR1C2 BTN2A1 TENM4 ASS1 DOCK6

6.95e-0619910361aa99d21bf61b86df4a966dc47634044430aa39f
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

CTSC DUSP1 SLC5A9 ANKH CELSR2

2.85e-0515310355424494ea1f09542799045a875cc3eac13de5079
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

HGFAC PLXDC1 ABCA12 WNT7A CELSR2

4.46e-05168103548089fa2d4a0f31a72405717119b767a92571f01
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DUSP1 WNT7A SLC5A9 ASB16 GALNT8

4.58e-051691035cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ACER2 SEMA4F HGFAC SLC26A5 ACSS3

4.85e-051711035a4d6b0f57eead11b01153688b06b2a45a3b488f2
ToppCelldroplet-Marrow-nan-3m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYADM CTSC DUSP1 PLXNB2 SOAT1

4.85e-051711035992df143d76f9e7fb1997a8996f61e941f0f9d4f
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2|E18.5-samps / Age Group, Lineage, Cell class and subclass

DRAM1 CTSC AOX1 ASS1 SOAT1

5.12e-051731035f6e36ea98a9c669ff393d141455aaecef083f738
ToppCellImmune_cells-Monocytes|Immune_cells / Lineage and Cell class

MYADM CTSC DUSP1 ASS1 SOAT1

5.12e-0517310353eced40a65453a023a1673658592e7e2a099119b
ToppCellE17.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEMA4F DRAM1 CTSC ASS1 SOAT1

5.26e-05174103568914ec843f58ecff3e6412544a341daf8a01cac
ToppCellNasal_Brush-Epithelial-Basal_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MARVELD1 ANKH PTPRD WNT10A EMP3

5.56e-051761035fc5787946f5a10056d326d070620575ae4081836
ToppCellNasal_Brush-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MARVELD1 ANKH PTPRD WNT10A EMP3

5.56e-0517610355daaba0853afe7d20d4635169ccd4f96e735b938
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM4 CELSR2 COL21A1 CNTN2 ACSS3

6.34e-0518110353aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM4 CELSR2 COL21A1 CNTN2 ACSS3

6.34e-051811035997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM4 CELSR2 COL21A1 CNTN2 ACSS3

6.34e-051811035e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Esophagus_Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

CES1P1 UGT1A5 AKR1C1 UGT1A4

6.47e-059310344ab8c28f7c47129ac633bcfdc7ccc8f7793464d5
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYADM PLXDC1 CTSC ASS1 SOAT1

6.51e-051821035bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CES1 CTSC ACP5 EMP3 SOAT1

6.68e-05183103502deb595819fb864a934fd0fcaad684f1ca42964
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 TRANK1 TENM4 PTPRD CNTN2

6.86e-0518410352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MARVELD1 PPP1R12A PTGIS EMP3 DOCK6

6.86e-05184103594748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MARVELD1 PPP1R12A PTGIS EMP3 DOCK6

6.86e-051841035819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 TRANK1 TENM4 PTPRD CNTN2

6.86e-051841035ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 TRANK1 TENM4 PTPRD CNTN2

6.86e-0518410352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellControl-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

CES1P1 CTSC ACP5 AKR1C1 AKR1C2

7.04e-05185103585cb81759589a26d83676cffbf2bc37399683c10
ToppCellFrontal_cortex-Endothelial|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

LRRK1 PTGFR PTGIS EMP3 DOCK6

7.59e-051881035a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

CES1P1 CTSC ACP5 AKR1C1 AKR1C2

8.18e-051911035a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYADM CES1 PPP1R12A GDNF COL21A1

8.59e-051931035a402e736440684ebe123673b6b0c6fcd8fa057b2
ToppCell10x5'-Liver|World / Manually curated celltypes from each tissue

CTSC DUSP1 AOX1 AKR1C1 ASS1

8.59e-051931035d010d47d763c99e68aede59345392f2a8c77d7ac
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTSC INSR PTGFR AKR1C1 ASS1

8.59e-05193103521c397912f2dd1f4115cddbdc01a6a9beb1332cc
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

AOX1 PTGIS AKR1C1 AKR1C2 ANKRD44

8.59e-051931035dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC NUBP1 PLXNB2 AHCY SOAT1

8.59e-0519310355a201ee6f132357c9aacfbad3ae56ed9854c25fd
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ACP5 PTGIS TENM4 PTPRD EMP3

8.59e-051931035035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GALE AKR1C1 AKR1C2 ASS1 SEL1L3

8.80e-0519410352172d951896265243d14996eacce5aab5e14e26e
ToppCellIPF-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

AOX1 PTGIS AKR1C1 AKR1C2 SOAT1

8.80e-051941035da3e1d39575969a069ef43e552afe94b2f441d0b
ToppCellMacrophages-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

MYADM CES1 CTSC DUSP1 ACP5

8.80e-051941035543b856b0fd883550c8f14baeae08fb9bf1a7768
ToppCellBLOOD--(1)_T_cell-(1)_EM_CTLs|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CES1 CTSC PSMB9 YPEL1 EMP3

9.01e-0519510357df67ad5c62235474ee56ea07a957253d45f066b
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXDC1 PPP1R12A GDNF PTPRD EMP3

9.01e-05195103519347b7e8d3ea67e0fddd948078abcab9d364a2d
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSR PTGFR AKR1C1 ASS1 SEL1L3

9.01e-051951035460e12044905370797fd9774e99c3aedaebfe343
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXDC1 PPP1R12A GDNF PTPRD EMP3

9.01e-05195103555b4030f078173b0136990fae87b6eaf44c58f33
ToppCellMacrophages-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CTSC ACP5 AKR1C2 EMP3 SOAT1

9.01e-051951035e48bf57e6da23fbb4637a02387155f825455c49f
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSR PTGFR AKR1C1 ASS1 SEL1L3

9.01e-051951035ff9f6b38f41dc5660b746fe40ceaddfb2958acd3
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GALE INSR PTGFR AKR1C1 ASS1

9.23e-051961035c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DUSP1 PTGFR GDNF TENM4 EMP3

9.23e-051961035fd0a2b863dedaf08d18e7f67da18ac7e853991e4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSR PTGFR AKR1C1 ASS1 SEL1L3

9.23e-0519610351ff4b41817556a6e573f0737819a5cc24a7ef821
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYADM DRAM1 CES1 CTSC EMP3

9.23e-051961035a7adc0e0baef261d0937e4e8351321d41beca82f
ToppCellBronchial-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA12 AOX1 DYNLT2 SPTBN4 GALNT8

9.23e-05196103596e5c6d155273e82ebafa180df8bb589c3e3e54e
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTSC INSR PTGFR AKR1C1 SEL1L3

9.23e-0519610358e909c31733762646359fe78b645cbd60237459e
ToppCellBronchial-NucSeq-Stromal-Mesofibroblastic-Mesothelia|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA12 AOX1 DYNLT2 SPTBN4 GALNT8

9.23e-051961035ce13af36fc2932e8125013041742593ff3d07e86
ToppCellCOPD-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

AOX1 PTGIS AKR1C1 AKR1C2 SOAT1

9.23e-0519610354930eeb303d174c28fd91021723e26fdf1af9170
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYADM CES1 PPP1R12A COL21A1 EMP3

9.46e-05197103594a7270ea6d4b586f58875c9e4071ce0f683ef7e
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDNF TRANK1 TENM4 AHCY POPDC3

9.46e-051971035e5ab45cfe4ebd02ca25029d87bece70dfbb4adc4
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTSC DUSP1 PTGFR GDNF EMP3

9.46e-051971035fc718a254bda4df2d62975d04393492fb75ab305
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MARVELD1 PLXDC1 PTGIS AKR1C2 PTPRD

9.69e-0519810354f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellBronchial_Brush-Epithelial-Club|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

GALE CTSC AKR1C1 ASS1 SEL1L3

9.69e-05198103561292a2b5aacb6080a679a31b70a211bdec59a3b
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Luminal_Macrophages|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

CES1 CTSC ACP5 TXNRD1 SOAT1

9.69e-051981035382ad6ebc6e0274ace361de72c0a3df05c846456
ToppCell(5)_Fibroblasts-(5)_Fibroblast-D|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CTSC AOX1 PTGFR PTGIS AKR1C1

9.69e-051981035fd14efd8e6c74a04bde985c08dc34217c0ef1bab
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTSC INSR PTGFR AKR1C1 ASS1

9.69e-051981035778fee7020c82d11ff3984a8e482a23e5d58165f
ToppCellmoderate-Epithelial-Secretory|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GALE PLXNB2 AKR1C1 AKR1C2 ASS1

9.69e-0519810357d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTSC INSR AKR1C1 PTPRD SEL1L3

9.69e-051981035be305d89d48c67ce922fa71aaf15e24d00c89ff6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CES1 PTGIS AKR1C1 AKR1C2 ASS1

9.92e-051991035dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell343B-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PSMB9 PTGIS AKR1C1 AKR1C2

9.92e-05199103508c7e631b2e203dd7dcb75a7f9377d292bc5a0fd
ToppCell343B-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PSMB9 PTGIS AKR1C1 AKR1C2

9.92e-0519910354338bf6cafc26c5d6497955d91914f84bacfacfa
ToppCellBronchial_Brush-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

GALE CTSC AKR1C1 ASS1 SEL1L3

9.92e-05199103553b87edccc89a3e8a6c5166472f9ef24fcba416c
ToppCell(04)_Interm._basal>secr.|World / shred by cell type by condition

CTSC INSR AKR1C1 AKR1C2 ASS1

9.92e-051991035ed399244433f781fc291a9bff16825b8a3ca294f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYADM CTSC DUSP1 ACP5 EMP3

9.92e-05199103581b3cb41abbee9785041170d0469edc50b622d7e
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

CTSC AOX1 PTGIS AKR1C1 EMP3

9.92e-051991035f19c683f38bca3bfee40396f27423441051dec67
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CES1 PTGIS AKR1C1 AKR1C2 ASS1

9.92e-051991035c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYADM CTSC DUSP1 ACP5 EMP3

9.92e-0519910353216fdaba8be8e8e715aceb2c29f1ad5cc02f8ae
ToppCellbackground-Hepatocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

CES1 DUSP1 AOX1 AKR1C1 ASS1

1.02e-042001035423cca10df6ae0489a8fe7e7df87e70364dac022
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CES1 CTSC ACP5 KLHL33 SOAT1

1.02e-0420010352cca77b2c9d829daa674a844e068f2b083e90d6e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PLXDC1 ACP5 CDH23 LRRK1 DOCK6

1.02e-042001035aafe594c88710f8c53d59667cdac5035e08f5511
ToppCell(5)_Epithelial_cells-(5)_Epi_suprabasal|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MYADM PSMB9 ASS1 WNT10A EMP3

1.02e-04200103592382ca82da3e435ccbee1c73261d55164d54779
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PLXDC1 ACP5 CDH23 LRRK1 DOCK6

1.02e-042001035a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCNP PTGFR AKR1C1 AKR1C2

2.22e-041281034076ba9de63b9a4b5a2f7e7924b9a86e8eafce91f
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 GJD4 TRANK1 CELSR2

3.21e-0414110344aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 GJD4 TRANK1 CELSR2

3.21e-041411034e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 GJD4 TRANK1 CELSR2

3.30e-041421034759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellP03-Epithelial-epithelial_progenitor_cell-epi_progenitor|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DRAM1 CTSC SGK2 SOAT1

4.16e-041511034fce04bce66411c21cd5d4d41375f26f1f50f3348
ToppCellCOVID-19-Heart-Adipocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH2 TENM4 ASS1 ACSS3

4.38e-04153103493958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PTGFR PTGIS AKR1C1

4.49e-041541034dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PTGFR PTGIS AKR1C1

4.49e-0415410344bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

SEMA4F DRAM1 ASS1 SEL1L3

4.60e-0415510349cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MARVELD1 DRAM1 KLHL33 ACSS3

4.82e-0415710341e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCellAdult-Immune-mast_cell-D175|Adult / Lineage, Cell type, age group and donor

ACOT6 TRANK1 GALNT8 RUNDC1

5.06e-0415910349f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCellNS-critical-d_07-13-Epithelial-Basal|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AKR1C1 AKR1C2 ASS1 WNT10A

5.18e-041601034f538ce75500773b5dda53fec4cde2f557d816f4e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AOX1 SGK2 PTPRD ACAD11

5.18e-041601034c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
Drugandrosterone glucuronide

UGT1A5 AOX1 AKR1C1 AKR1C2 UGT1A4 UGT1A3

3.30e-08431006CID000114833
Drug9-OH-risperidone

UGT1A5 PTGIS UGT1A4 UGT1A3

1.29e-06191004CID000475100
DrugBenzamidoxime hydrochloride

UGT1A5 AOX1 UGT1A4 UGT1A3

1.98e-06211004CID000069186
Drugamonafide

LIAS UGT1A5 UGT1A4 UGT1A3

2.41e-06221004CID000050515
Drugphenanthridine

UGT1A5 AOX1 UGT1A4 UGT1A3

2.91e-06231004CID000009189
Drugphenolphthalein

UGT1A5 AKR1C1 AKR1C2 UGT1A4 UGT1A3

5.63e-06581005CID000004764
Drugmono-(2-ethylhexyl)phthalate

ABCA12 DUSP1 INSR AOX1 CDH23 SLC5A9 GDNF TXNRD1 SPTBN4 PTPRD CELSR2 AHCY POPDC3

6.17e-0665810013ctd:C016599
DrugAC1MRQNQ

UGT1A5 UGT1A4 UGT1A3

6.77e-0691003CID003522271
DrugDHPASiU

UGT1A5 UGT1A4 UGT1A3

6.77e-0691003CID000197602
Drug3-iodophenol

UGT1A5 UGT1A4 UGT1A3

6.77e-0691003CID000012272
DrugAC1L4J7U

UGT1A5 UGT1A4 UGT1A3

6.77e-0691003CID000186631
DrugChebi:32663

UGT1A5 UGT1A4 UGT1A3

6.77e-0691003CID005460873
DrugAC1L1JAL

GIN1 UGT1A5 UGT1A4 UGT1A3

7.65e-06291004CID000004954
Drugtrans-3'-hydroxycotinine

UGT1A5 AOX1 UGT1A4 UGT1A3

7.65e-06291004CID000000414
Drugdihydroartemisinin

UGT1A5 ARMC9 UGT1A4 UGT1A3

8.79e-06301004CID000107770
Drugketoprofen

CES1 UGT1A5 UGT1A4 UGT1A3 EMP3

9.17e-06641005CID000003825
DrugMeldola

CES1 UGT1A5 ACP5 UGT1A4 UGT1A3

1.24e-05681005CID000081507
Drug4-nitrophenyl)imidazole

UGT1A5 UGT1A4 UGT1A3

1.32e-05111003CID000123155
DrugAC1O5XMV

UGT1A5 UGT1A4 UGT1A3

1.32e-05111003CID006442661
DrugN-OH-DABZ

UGT1A5 UGT1A4 UGT1A3

1.76e-05121003CID000051366
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A5 UGT1A4 UGT1A3

1.76e-05121003CID000088735
Drug2,4,6-TCB

UGT1A5 UGT1A4 UGT1A3

1.76e-05121003CID000037247
Drugnonanoyl-N-methylglucamide

UGT1A5 UGT1A4 UGT1A3

1.76e-05121003CID000160090
Drug7,7,7-triphenylheptanoic acid

UGT1A5 UGT1A4 UGT1A3

1.76e-05121003CID000276709
Drugcatechol

LIAS PLXDC1 UGT1A5 AKR1C1 AKR1C2 UGT1A4 UGT1A3 TRPV5

1.80e-052571008CID000000289
Druganisole

UGT1A5 PTGIS UGT1A4 UGT1A3

1.85e-05361004CID000007519
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

1.91e-0521002DB07768
Drugafloqualone

UGT1A4 UGT1A3

1.91e-0521002ctd:C033541
Drug6beta-hydroxytestosterone

UGT1A5 UGT1A4 UGT1A3 CNTN2

2.07e-05371004CID000065543
Drugtritanol

UGT1A5 UGT1A4 UGT1A3

2.28e-05131003CID000006457
Drug5-azido-UDP-glucuronic acid

UGT1A5 UGT1A4 UGT1A3

2.28e-05131003CID003081279
Drugcotinine-N-glucuronide

UGT1A5 UGT1A4 UGT1A3

2.28e-05131003CID000000411
Drugacacetin

UGT1A5 AKR1C2 UGT1A4 UGT1A3

2.31e-05381004CID005280442
DrugSalicylic Acid

PSMB9 AKR1C1 AKR1C2 UGT1A3

2.56e-05391004ctd:D020156
Drugpropranolol glucuronide

UGT1A5 UGT1A4 UGT1A3

2.89e-05141003CID000119515
DrugPCB-61

UGT1A5 UGT1A4 UGT1A3

2.89e-05141003CID000036401
DrugAC1Q6O8B

UGT1A5 PTGIS UGT1A4 UGT1A3

3.13e-05411004CID000000334
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A5 UGT1A4 UGT1A3

3.60e-05151003CID000040469
Drugafloqualone

UGT1A5 UGT1A4 UGT1A3

3.60e-05151003CID000002040
Drugnaphthyl sulphate

UGT1A5 UGT1A4 UGT1A3

3.60e-05151003CID000114775
Drugcoumarin-3-carboxylic acid

UGT1A5 UGT1A4 UGT1A3

3.60e-05151003CID000010752
Drugsulforaphane nitrile

UGT1A5 UGT1A4 UGT1A3

3.60e-05151003CID000543743
Drug7,8-benzoquinoline

UGT1A5 AKR1C2 UGT1A4 UGT1A3

3.79e-05431004CID000009191
Drugquercetin-3,4'-diglucoside

UGT1A5 UGT1A4 UGT1A3

4.42e-05161003CID005320835
Drug1'-hydroxyestragole

UGT1A5 UGT1A4 UGT1A3

4.42e-05161003CID000040003
Drugbilirubin-phosphate

UGT1A5 UGT1A4 UGT1A3

4.42e-05161003CID005497144
DrugNSC9700

MYH2 POLR1A UGT1A5 ACP5 INSR PTGIS AKR1C1 AKR1C2 UGT1A4 UGT1A3 IHH

4.72e-0557810011CID000005408
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A5 UGT1A4 UGT1A3

5.35e-05171003CID000003573
Drug6-hydroxychrysene

UGT1A5 UGT1A4 UGT1A3

5.35e-05171003CID000037766
Drugcyclopentanol

AKR1C1 AKR1C2

5.71e-0531002ctd:C016327
Drugcyclopentanone

AKR1C1 AKR1C2

5.71e-0531002ctd:C007201
Drug5-dihydrodeoxycorticosterone

AKR1C1 AKR1C2

5.71e-0531002ctd:C454687
Drug4-benzoylbenzoic acid

AKR1C1 AKR1C2

5.71e-0531002ctd:C058818
Drugdichloro(4-cymene)ruthenium(II)

AKR1C1 AKR1C2

5.71e-0531002ctd:C530610
DrugAC1L1G0K

UGT1A5 UGT1A4 UGT1A3 TRPV5

6.38e-05491004CID000003473
DrugSureCN12722713

UGT1A5 UGT1A4 UGT1A3

6.39e-05181003CID005488034
Drugethyl-beta-D-6-glucosiduronic acid

UGT1A5 UGT1A4 UGT1A3

6.39e-05181003CID000152226
DrugBr 2

UGT1A5 UGT1A4 UGT1A3

6.39e-05181003CID003060900
Drug2,3,7-trichlorodibenzo-p-dioxin

UGT1A5 UGT1A4 UGT1A3

6.39e-05181003CID000036614
DrugApApG

UGT1A5 UGT1A4 UGT1A3

6.39e-05181003CID003081975
DrugC1 11-32

UGT1A5 UGT1A4 UGT1A3

6.39e-05181003CID000443077
DrugC11131

UGT1A5 UGT1A4 UGT1A3

6.39e-05181003CID000443076
Drugbeta-Naphthoflavone

CTSC UGT1A5 YPEL1 PTGFR AKR1C1 SGK2 TXNRD1 UGT1A4 UGT1A3 MEGF8 IHH EMP3 TRPV5

6.80e-0582810013ctd:D019324
Drugdeoxypyridinoline

APPBP2 CTSC ACP5 IHH TRPV5

7.26e-05981005CID000105071
Drugandrostane-3,17-dione

INSR ARMC9 AKR1C1 AKR1C2

7.47e-05511004CID000000443
Drug5alpha-spirostan-3beta-ol

UGT1A5 UGT1A4 UGT1A3

7.57e-05191003CID000091433
Drugalmokalant

UGT1A5 UGT1A4 UGT1A3

7.57e-05191003CID003033962
Drug3-hydroxyandrostan-17-one

UGT1A5 AKR1C1 AKR1C2 UGT1A4 UGT1A3

8.79e-051021005CID000000225
Drugtectochrysin

UGT1A5 UGT1A4 UGT1A3

8.88e-05201003CID005281954
DrugAC1L1OBF

UGT1A5 UGT1A4 UGT1A3

8.88e-05201003CID000032736
Drug4'-hydroxydiclofenac

UGT1A5 UGT1A4 UGT1A3

8.88e-05201003CID000116545
DrugHCG 004

UGT1A5 AOX1 UGT1A4 UGT1A3

9.36e-05541004CID000064928
Drugallicin

CTSC PTGIS TNKS TRPV5

9.36e-05541004CID000065036
Drugestrone-d4

UGT1A5 AKR1C1 UGT1A4 UGT1A3 ARSD ACAD11

9.92e-051681006CID000000698
Drugestriol-16-glucuronide

UGT1A5 UGT1A4 UGT1A3

1.03e-04211003CID000122281
Drugabequose

ARMC9 AKR1C1 GMPPB

1.03e-04211003CID000160540
DrugFlunitrazepam

AKR1C1 AKR1C2 UGT1A3

1.03e-04211003ctd:D005445
Drugconiferaldehyde

AKR1C1 AKR1C2 TXNRD1

1.03e-04211003ctd:C075384
Drugdulcin

UGT1A5 UGT1A4 UGT1A3

1.03e-04211003CID000009013
DrugSodium Dodecyl Sulfate

LIAS ABCA12 AKR1C1 AKR1C2 TXNRD1

1.05e-041061005ctd:D012967
DrugInvader

UGT1A5 CDH23 UGT1A4 UGT1A3

1.08e-04561004CID006442259
Drug2,4,5-Trichlorophenoxyacetic Acid

ACER2 MPDZ SGK2 IHH GMPPB

1.10e-041071005ctd:D015085
Drugcloxazolam

AKR1C1 AKR1C2

1.14e-0441002ctd:C005522
Drugtetrahydrodeoxycorticosterone

AKR1C1 AKR1C2

1.14e-0441002ctd:C009413
DrugPregnanes

AKR1C1 AKR1C2

1.14e-0441002ctd:D011278
Drugtetralol

AKR1C1 AKR1C2

1.14e-0441002ctd:C019106
Druggliquidone

AKR1C1 AKR1C2

1.14e-0441002ctd:C010969
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C1 AKR1C2

1.14e-0441002ctd:C018156
DrugN-methylpiperazine

UGT1A5 UGT1A4 UGT1A3

1.19e-04221003CID000053167
DrugNSC740136

UGT1A5 ACP5 UGT1A4 UGT1A3 WNT10A

1.20e-041091005CID000003706
Drug4-nitrophenol

LIAS CES1 UGT1A5 ACP5 UGT1A4 UGT1A3

1.32e-041771006CID000000980
DrugSN-38G

CES1 UGT1A5 UGT1A4 UGT1A3

1.32e-04591004CID000443154
Drugamidoxime

UGT1A5 UGT1A4 UGT1A3

1.37e-04231003CID000465967
Drugestradiol-3-glucuronide

UGT1A5 UGT1A4 UGT1A3

1.37e-04231003CID000066651
Drug3-OH

UGT1A5 UGT1A4 UGT1A3 ACSS3

1.51e-04611004CID000068152
DrugTranilast sodium

GIN1 UGT1A5 UGT1A4 UGT1A3 COL21A1

1.55e-041151005CID000005527
DrugAS-3201

UGT1A5 UGT1A4 UGT1A3

1.56e-04241003CID000153948
DrugLetrozole [112809-51-5]; Up 200; 14uM; HL60; HT_HG-U133A

DUSP1 INSR PTGIS ANKH CELSR3 DOCK6

1.68e-0418510062916_UP
Drug5-MOP

UGT1A5 UGT1A4 UGT1A3

1.76e-04251003CID000002355
DrugAzMC

UGT1A5 UGT1A4 UGT1A3

1.76e-04251003CID000064986
DiseaseDisorders of Sex Development

PPP1R12A AKR1C1 AKR1C2

1.35e-0671013C0036875
DiseaseX-11793--oxidized bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0021260
DiseaseSuccinimide measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0022118
DiseaseX-11530 measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0800696
DiseaseX-10458 measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0800692
DiseaseX-24849 measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0802740
DiseaseX-16946 measurement

UGT1A5 UGT1A4 UGT1A3

2.15e-0681013EFO_0800766
DiseaseX-11442 measurement

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0021236
DiseaseX-11441 measurement

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0801036
DiseaseX-11880 measurement

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A5 UGT1A4 UGT1A3

3.22e-0691013EFO_0004570, GO_0009410
Diseasebilirubin measurement, response to tenofovir

UGT1A5 UGT1A4 UGT1A3

4.59e-06101013EFO_0004570, EFO_0009279
DiseaseX-21448 measurement

UGT1A5 UGT1A4 UGT1A3

4.59e-06101013EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A5 UGT1A4 UGT1A3

4.59e-06101013EFO_0802185
DiseaseX-23974 measurement

UGT1A5 UGT1A4 UGT1A3

4.59e-06101013EFO_0800867
Diseasefree androgen index

HGFAC MYH2 UGT1A5 INSR R3HDM2 GDNF AKR1C2 UGT1A4 SOAT1

5.74e-063741019EFO_0007005
Diseasehistidine betaine (hercynine) measurement

UGT1A5 UGT1A4 UGT1A3

6.30e-06111013EFO_0800972
DiseaseX-21796 measurement

UGT1A5 UGT1A4 UGT1A3

6.30e-06111013EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

6.30e-06111013EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A5 UGT1A4 UGT1A3

6.30e-06111013EFO_0010219
Diseasep-cresol glucuronide measurement

UGT1A5 UGT1A4 UGT1A3

8.37e-06121013EFO_0800079
Diseasebiliverdin measurement

UGT1A5 UGT1A4 UGT1A3

8.37e-06121013EFO_0021033
Diseaseretinol dehydrogenase 16 measurement

UGT1A5 UGT1A4 UGT1A3

1.09e-05131013EFO_0802007
DiseaseEndometrioma

DUSP1 PTGFR ANKH AKR1C1 AKR1C2 IHH

1.99e-051611016C0269102
DiseaseEndometriosis

DUSP1 PTGFR ANKH AKR1C1 AKR1C2 IHH

1.99e-051611016C0014175
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A5 UGT1A4 UGT1A3

2.56e-05171013EFO_0004611, EFO_0007800
Diseaseangiopoietin-related protein 1 measurement

UGT1A5 UGT1A4 UGT1A3

3.06e-05181013EFO_0801382
DiseaseNeoplasms, Hormone-Dependent

AKR1C1 AKR1C2

3.47e-0531012C0027661
Diseaseurate measurement, spine bone mineral density

UGT1A5 UGT1A4 UGT1A3 PTPRD

4.76e-05581014EFO_0004531, EFO_0007701
Diseasetissue factor measurement

UGT1A5 UGT1A4 UGT1A3

4.95e-05211013EFO_0010623
DiseaseHermaphroditism

AKR1C1 AKR1C2

1.15e-0451012C0019269
DiseaseAmbiguous Genitalia

AKR1C1 AKR1C2

1.15e-0451012C0266362
DiseasePseudohermaphroditism

AKR1C1 AKR1C2

1.15e-0451012C0033804
DiseaseIntersex Conditions

AKR1C1 AKR1C2

1.15e-0451012C2930618
DiseaseSex Differentiation Disorders

AKR1C1 AKR1C2

1.15e-0451012C2930619
Diseasemetabolite measurement

CES1 UGT1A5 INSR PSMB9 SLC5A9 ACOT6 AKR1C2 UGT1A4 UGT1A3

1.33e-045601019EFO_0004725
Diseasexanthurenate measurement

UGT1A5 UGT1A4 UGT1A3

1.33e-04291013EFO_0010551
Diseaseresponse to dolutegravir

UGT1A5 UGT1A4 UGT1A3

1.48e-04301013EFO_0600017
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

SLC11A2 AOX1 TXNRD1

1.80e-04321013DOID:332 (is_implicated_in)
Diseasecholelithiasis

LIAS UGT1A5 UGT1A4 UGT1A3

2.42e-04881014EFO_0004799
DiseaseX-24747 measurement

ACOT6 ACAD11

3.20e-0481012EFO_0022135
Diseasewhite matter microstructure measurement

DIP2B DRAM1 WNT7A ARMC9 ACAD11 TNKS SOAT1

3.96e-043901017EFO_0005674
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

HGFAC CES1 SPG11 TENM4 CELSR2 DOCK6

5.06e-042911016EFO_0008317, EFO_0020946
Diseasegallstones

LIAS UGT1A5 UGT1A4 UGT1A3

5.28e-041081014EFO_0004210
Diseasepregnenetriol sulfate measurement

UGT1A5 UGT1A4

6.25e-04111012EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A5 UGT1A4

6.25e-04111012EFO_0600039
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

CDH23 CELSR2

7.49e-04121012EFO_0801493
Diseasegranulins measurement

CDH23 CELSR2

7.49e-04121012EFO_0008141
DiseaseHirschsprung's disease (implicated_via_orthology)

GDNF IHH

7.49e-04121012DOID:10487 (implicated_via_orthology)
Diseaseserum alanine aminotransferase measurement

DIP2B HGFAC INSR PLXNB2 GDNF TRANK1 TENM4 CELSR2 AHCY TNKS

8.00e-0486910110EFO_0004735
Diseasepregnenetriol disulfate measurement

UGT1A5 UGT1A4

8.83e-04131012EFO_0800587
Diseaseiron deficiency anemia (biomarker_via_orthology)

SLC11A2 IREB2

8.83e-04131012DOID:11758 (biomarker_via_orthology)
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

DIP2B HGFAC AHCY

9.46e-04561013EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

HGFAC INSR R3HDM2 CELSR2 TNKS

9.76e-042201015EFO_0004529, EFO_0008317
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

HGFAC MYH2 INSR SPG11 CELSR2

1.02e-032221015EFO_0008317, EFO_0020943
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

HGFAC INSR R3HDM2 CELSR2 TNKS

1.06e-032241015EFO_0004530, EFO_0008317
Diseaseglycine measurement

INSR R3HDM2 TENM4 PTPRD

1.28e-031371014EFO_0009767
Diseaseresponse to methotrexate

AKR1C1 AKR1C2

1.35e-03161012GO_0031427
DiseaseLiver Cirrhosis, Experimental

MYADM DRAM1 ACP5 PSMB9 R3HDM2 AKR1C1 SGK2 PTPRD SOAT1

1.37e-037741019C0023893
Diseasepartial epilepsy

PTPRD ASS1

1.53e-03171012EFO_0004263
DiseaseX-21441 measurement

UGT1A5 UGT1A4

1.53e-03171012EFO_0800814
Diseasealpha-L-iduronidase measurement

DRAM1 TMEM271

1.53e-03171012EFO_0020139
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

HGFAC CES1 SPG11 CELSR2

1.54e-031441014EFO_0004611, EFO_0020943
DiseaseContact Dermatitis

DUSP1 AKR1C2 TXNRD1

1.88e-03711013C0011616
DiseaseContact hypersensitivity

DUSP1 AKR1C2 TXNRD1

1.88e-03711013C0162351
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

HGFAC CES1 CELSR2 DOCK6

1.92e-031531014EFO_0004611, EFO_0020946
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

HGFAC CES1 CELSR2 DOCK6

1.92e-031531014EFO_0004611, EFO_0020944
Diseasevery low density lipoprotein cholesterol measurement

HGFAC INSR R3HDM2 CELSR2 TNKS

2.04e-032601015EFO_0008317
DiseaseX-24309 measurement

ACOT6 ACAD11

2.12e-03201012EFO_0800872
DiseaseDisproportionate short stature

ACP5 ANKH IHH

2.37e-03771013C0878659
Diseaseapolipoprotein A 1 measurement

HGFAC CES1 R3HDM2 SPG11 GDNF BTN2A1 TRANK1 CELSR2 DOCK6

2.54e-038481019EFO_0004614
Diseasetriglyceride measurement, high density lipoprotein cholesterol measurement

HGFAC R3HDM2 TENM4 CELSR2 DOCK6

2.55e-032741015EFO_0004530, EFO_0004612
Diseaseprogranulin measurement

CDH23 CELSR2

2.56e-03221012EFO_0004625
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

HGFAC R3HDM2 CELSR2 TNKS

2.58e-031661014EFO_0004530, EFO_0004611
Diseasethyroxine measurement

UGT1A5 UGT1A4 UGT1A3

2.93e-03831013EFO_0005130
Diseasehormone measurement

UGT1A5 UGT1A4 UGT1A3

3.03e-03841013EFO_0004730

Protein segments in the cluster

PeptideGeneStartEntry
QYHSLDVIGFLLAVV

UGT1A3

486

P35503
YHAASGDVAELRVEL

MAMDC4

146

Q6UXC1
VVFEAVAAGVAHSYV

MAMDC4

941

Q6UXC1
VAAGVAHSYVALDDL

MAMDC4

946

Q6UXC1
TYDGLALAAHENVVV

CES1

151

P23141
DAVIGHYSLLLQVSG

EPB42

111

P16452
LYHAVIARVGAAVSE

ARSD

536

P51689
LVVVGIGSVYFHATL

ACER2

71

Q5QJU3
AAELGTEIAASLLYH

ABCA12

476

Q86UK0
VAAARGLEQHVALYL

ASB16

216

Q96NS5
VALYLEHGADVGLRT

ASB16

226

Q96NS5
RASVHAVLGEAIFYG

ACOT6

371

Q3I5F7
EDYEVALSVGHLASL

APPBP2

466

Q92624
GYLVLHVQAIDADAG

CELSR2

521

Q9HCU4
LAVHLLDSYLSAGRV

CCNP

131

Q9H8S5
DLAGHNDTAIIGIYI

CDH23

2936

Q9H251
AGTILYHAHLDIEAF

ASS1

286

P00966
VSGLSHVDYALIAEE

ACAD11

441

Q709F0
LLVIGHLVVNAAYSA

ALG12

346

Q9BV10
AAALVHIYLDGSVLV

AOX1

1026

Q06278
FALGSIEGRVAIHYI

RAE1

231

P78406
GRHSDLAALYTIVAV

R3HDM2

921

Q9Y2K5
AIENAHVLLYLGDSV

IREB2

736

P48200
LSVVRYLATAHIDGA

NUBP1

181

P53384
YLATAHIDGAVIITT

NUBP1

186

P53384
STYDGLALAAHENVV

CES1P1

151

Q9UKY3
AAFIISYVVAVLSGH

DRAM1

21

Q8N682
AHAAAILEGQLYVSG

KLHL33

361

A6NCF5
AIGAVIHYLLQVGSE

NCDN

371

Q9UBB6
VAAYFGHTAVVQELL

LRRK1

126

Q38SD2
ADYHNLIGVTAELVD

ARMC9

236

Q7Z3E5
LAAAGVDHVILAVSY

GMPPB

41

Q9Y5P6
VFSVYVLHRGATLAA

GJD4

91

Q96KN9
IYVAGLVAHSDLDER

SYNCRIP

46

O60506
HLINGAIAVFVYASD

PTGFR

81

P43088
YVANTVFHSILAGLA

PCNX4

136

Q63HM2
HLAVDEASGVVYLGA

PLXNB2

36

O15031
AEAHFALIHYAGVVD

MYH2

576

Q9UKX2
LTAATGERHDALYVV

DIP2B

1446

Q9P265
SVAHAVAAVGSRLYI

MEGF8

1841

Q7Z7M0
VALSGLDVYAHNVET

LIAS

226

O43766
AINLLAYVADLVHSA

MYADM

301

Q96S97
DLGHVALYVVAAVVS

SLC11A2

501

P49281
TAIHLNVTDLGLGYE

GDNF

121

P39905
LAVAYGHIDAVSLLL

ANKRD44

676

Q8N8A2
VAVAALLLGAAGHLY

INSR

16

P06213
GVIYLVTITAAGVDH

PSMB9

191

P28065
YQELHVDSVGAAALL

HGFAC

316

Q04756
AGYIGSHTVLELLEA

GALE

11

Q14376
AVAAAHSVVLGYLQD

EXOC4

351

Q96A65
YKAAVIGTRLHAAVA

TMEM167B

46

Q9NRX6
VHAAALVAEYLALLE

DOCK6

1621

Q96HP0
LAGAYHAVVLLDERS

DUSP1

76

P28562
HLTGELYVGQLIAEA

GALNT8

536

Q9NY28
ELTNHAVLLVGYGTD

CTSC

401

P53634
SGEHLTAAVESILYL

COL21A1

96

Q96P44
VVAGAIAAVFHTLIA

ANKH

91

Q9HCJ1
IAAVFHTLIAYSDLG

ANKH

96

Q9HCJ1
HGTIYASAELAVQAL

CNTN2

401

Q02246
RSYDEAILHLVVAGL

BTN2A1

131

Q7KYR7
HDVLAAALYGAATGI

MARVELD1

101

Q9BSK0
VFTGALIYAIHAEEI

EMP3

111

P54852
SAGLVRHLEEYAATL

CELSR3

2291

Q9NYQ7
DHAAAAIAKAGIPVY

AHCY

86

P23526
EGAIYHLASILFVVG

POPDC3

26

Q9HBV1
RVAAVSTHVALGAYA

IHH

316

Q14623
AYDHSRVLLSAIEGI

PTPRD

1391

P23468
GLDVLAIGVSYAHIL

OR52L1

226

Q8NGH7
GLDVLAIGVSYAHIL

OR52L2P

226

Q8NGH6
LVETAAHLGYSVVAI

RPP30

21

P78346
TVAVRDLLAHGLYAS

RUNDC1

431

Q96C34
LGDAVVEFLTSVHLY

DROSHA

971

Q9NRR4
IGYVTGVLAVLVHAA

SLC35D3

156

Q5M8T2
AVFAVSAVVHEYALA

SOAT1

451

P35610
HEALLYYVLAAETGI

SEL1L3

891

Q68CR1
SSLVVSLAHGAVIYA

POLR1A

1541

O95602
QEGGAAHVVAAYSLV

SEMA4F

631

O95754
AEVASAIGYLHSLNI

SGK2

141

Q9HBY8
YTNLHAVLLGDATEA

PTGIS

141

Q16647
FHLVYVDAIAIAIVG

SLC26A5

336

P58743
LLQGSVVADHDYIGL

GIN1

436

Q9NXP7
GRLAYHLAVVLGSAA

SLC52A2

306

Q9HAB3
ALDSRVGLHAYDISV

SLC5A9

26

Q2M3M2
NGLYVLAGVAESIHL

WDR18

91

Q9BV38
IVLVAYSALGSHREE

AKR1C1

211

Q04828
IVLVAYSALGSHREE

AKR1C2

211

P52895
GAYFRVLAEHGVAAL

ACSS3

376

Q9H6R3
DVVDGTYVAHVDLAL

SPG11

226

Q96JI7
RALLQAYIDGHSVVI

TXNRD1

56

Q16881
VLLTGLHAVADIYCE

YPEL1

66

O60688
LHSVEVEVSYFAAGI

ZYG11B

591

Q9C0D3
VEVSYFAAGIIAHLI

ZYG11B

596

Q9C0D3
GSDTLLGAIIIHEVY

MPDZ

1646

O75970
NAASYGHVDIAALLI

TNKS

876

O95271
QYHSLDVIGFLLAVV

UGT1A5

486

P35504
QLAAAREDYVLVAGH

ACP5

191

P13686
TALAVSHNGVLYIAE

TENM4

1471

Q6N022
LRTVYAGEHAEAIAS

SPTBN4

1901

Q9H254
VLLTGLHAVADIYCE

YPEL2

66

Q96QA6
FTYAIIAAGVAHAIT

WNT7A

106

O00755
LVAAIILAGIYINGH

PLXDC1

436

Q8IUK5
AFAYAIAAAGVVHAV

WNT10A

131

Q9GZT5
TLNHSAGVVEALYEA

TRANK1

2011

O15050
LIAIVYSHEARAALG

PRRT1B

206

A0A1B0GWB2
HAVSYINVGVLHALD

TMEM271

321

A0A286YF58
GALGETALHIAALYD

TRPV5

76

Q9NQA5
YVSHELVNAALLAGS

PP2D1

596

A8MPX8
QYHSLDVIGFLLAVV

UGT1A4

486

P22310
HEAESYVALVLVFAL

DYNLT2

181

Q8IZS6
TALHVAAAKGYTEVL

PPP1R12A

201

O14974