Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A8 SLC4A10 SLC39A5	2.21e-05	13	87	3	GO:0140410
GeneOntologyMolecularFunction	sodium,bicarbonate:chloride antiporter activity	SLC4A8 SLC4A10	5.61e-05	3	87	2	GO:0140892
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A8 SLC4A10	2.78e-04	6	87	2	GO:0008510
GeneOntologyMolecularFunction	calcium-induced calcium release activity	PKD2 RYR1	2.78e-04	6	87	2	GO:0048763
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC4A8 SLC4A10 SLC39A5	3.62e-04	32	87	3	GO:0015106
GeneOntologyBiologicalProcess	epithelium development	KRT23 MSX2 FLG NCOR2 RBM15 ADIPOQ AIMP2 ZFP36L1 KRT19 GLI2 CECR2 NR5A2 PKD2 DVL2 MMRN2 CDH23 LZTS2 CSMD1 TFAP2C ZIC3 TJP3	5.55e-07	1469	87	21	GO:0060429
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	MSX2 RBM15 GLI2 CECR2 PKD2 DVL2 MMRN2 LZTS2 CSMD1 TFAP2C ZIC3	1.57e-06	421	87	11	GO:0060562
GeneOntologyBiologicalProcess	mammary gland duct morphogenesis	MSX2 GLI2 CSMD1 TFAP2C	3.86e-05	45	87	4	GO:0060603
GeneOntologyBiologicalProcess	sensory organ development	KMT2C NEUROD2 GLI2 CECR2 PRSS56 DVL2 CDH23 C1QTNF5 PPP1R13L SLC39A5 ARSG ZIC3	5.50e-05	730	87	12	GO:0007423
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	MSX2 RBM15 GLI2 CECR2 PKD2 DVL2 MMRN2 LZTS2 CSMD1 TFAP2C ZIC3	5.77e-05	619	87	11	GO:0002009
GeneOntologyBiologicalProcess	heart morphogenesis	MSX2 NCOR2 RBM15 PKD2 DVL2 PPP1R13L RYR1 ZIC3	6.34e-05	321	87	8	GO:0003007
GeneOntologyBiologicalProcess	mammary gland development	MSX2 NCOR2 GLI2 IRS1 CSMD1 TFAP2C	6.39e-05	162	87	6	GO:0030879
GeneOntologyBiologicalProcess	tube development	GPLD1 MSX2 NCOR2 RBM15 NPPB AIMP2 ZFP36L1 GLI2 CECR2 PKD2 DVL2 MMRN2 LZTS2 CSMD1 TFAP2C HECA ZIC3	6.69e-05	1402	87	17	GO:0035295
GeneOntologyBiologicalProcess	epithelial cell differentiation	KRT23 MSX2 FLG NCOR2 ADIPOQ AIMP2 ZFP36L1 KRT19 GLI2 NR5A2 CDH23 TFAP2C TJP3	6.96e-05	870	87	13	GO:0030855
GeneOntologyBiologicalProcess	cochlea development	GLI2 CECR2 DVL2 CDH23	1.28e-04	61	87	4	GO:0090102
GeneOntologyBiologicalProcess	mammary gland morphogenesis	MSX2 GLI2 CSMD1 TFAP2C	1.64e-04	65	87	4	GO:0060443
GeneOntologyBiologicalProcess	chemical homeostasis	GPLD1 NCOR2 NPPB SLC4A8 ADIPOQ NR5A2 PKD2 SLC4A10 CDH23 BOLA1 IRS1 CSMD1 SLC30A3 SLC39A5 RYR1	2.12e-04	1249	87	15	GO:0048878
GeneOntologyBiologicalProcess	tube morphogenesis	GPLD1 MSX2 RBM15 NPPB ZFP36L1 GLI2 CECR2 PKD2 DVL2 MMRN2 LZTS2 CSMD1 TFAP2C ZIC3	2.46e-04	1125	87	14	GO:0035239
GeneOntologyBiologicalProcess	animal organ morphogenesis	MSX2 NCOR2 RBM15 GLI2 NR5A2 PKD2 DVL2 SLC4A10 CDH23 LZTS2 CSMD1 PPP1R13L TFAP2C RYR1 ZIC3	2.52e-04	1269	87	15	GO:0009887
GeneOntologyBiologicalProcess	determination of liver left/right asymmetry	PKD2 ZIC3	2.61e-04	6	87	2	GO:0071910
GeneOntologyBiologicalProcess	branching involved in mammary gland duct morphogenesis	MSX2 CSMD1 TFAP2C	2.71e-04	30	87	3	GO:0060444
GeneOntologyBiologicalProcess	embryo development	MSX2 NCOR2 TCF3 SLC4A8 ADIPOQ ZFP36L1 KRT19 GLI2 CECR2 NR5A2 PKD2 DVL2 CDH23 PPP1R13L TFAP2C ZIC3	3.00e-04	1437	87	16	GO:0009790
GeneOntologyBiologicalProcess	tissue morphogenesis	MSX2 RBM15 GLI2 CECR2 PKD2 DVL2 MMRN2 LZTS2 CSMD1 TFAP2C ZIC3	3.09e-04	750	87	11	GO:0048729
GeneOntologyBiologicalProcess	heart development	MSX2 NCOR2 RBM15 NPPB ZFP36L1 GLI2 PKD2 DVL2 PPP1R13L RYR1 ZIC3	3.34e-04	757	87	11	GO:0007507
Domain	Na/HCO3_transpt	SLC4A8 SLC4A10	2.17e-04	5	88	2	IPR003024
Domain	Filament	KRT23 NEFH KRT19 IFFO2	3.51e-04	71	88	4	SM01391
Domain	Filament	KRT23 NEFH KRT19 IFFO2	3.91e-04	73	88	4	PF00038
Domain	ANION_EXCHANGER_2	SLC4A8 SLC4A10	4.54e-04	7	88	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A8 SLC4A10	4.54e-04	7	88	2	PS00219
Domain	C1Q	ADIPOQ MMRN2 C1QTNF5	4.54e-04	32	88	3	SM00110
Domain	C1q	ADIPOQ MMRN2 C1QTNF5	4.54e-04	32	88	3	PF00386
Domain	IF	KRT23 NEFH KRT19 IFFO2	4.56e-04	76	88	4	IPR001664
Domain	PDZ	SHANK1 DVL2 SNX27 PDZD2 TJP3	5.41e-04	141	88	5	PF00595
Domain	C1q_dom	ADIPOQ MMRN2 C1QTNF5	5.44e-04	34	88	3	IPR001073
Domain	C1Q	ADIPOQ MMRN2 C1QTNF5	5.44e-04	34	88	3	PS50871
Domain	PDZ	SHANK1 DVL2 SNX27 PDZD2 TJP3	6.74e-04	148	88	5	SM00228
Domain	-	SHANK1 DVL2 SNX27 PDZD2 TJP3	7.17e-04	150	88	5	2.30.42.10
Domain	PDZ	SHANK1 DVL2 SNX27 PDZD2 TJP3	7.38e-04	151	88	5	PS50106
Domain	PDZ	SHANK1 DVL2 SNX27 PDZD2 TJP3	7.61e-04	152	88	5	IPR001478
Domain	Band3_cytoplasmic_dom	SLC4A8 SLC4A10	7.73e-04	9	88	2	IPR013769
Domain	Band_3_cyto	SLC4A8 SLC4A10	7.73e-04	9	88	2	PF07565
Domain	-	SLC4A8 SLC4A10	7.73e-04	9	88	2	3.40.1100.10
Domain	HCO3_cotransp	SLC4A8 SLC4A10	9.64e-04	10	88	2	PF00955
Domain	HCO3_transpt_C	SLC4A8 SLC4A10	9.64e-04	10	88	2	IPR011531
Domain	PTrfase/Anion_transptr	SLC4A8 SLC4A10	9.64e-04	10	88	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A8 SLC4A10	9.64e-04	10	88	2	IPR003020
Domain	CUB	CDCP2 C1QTNF5 CSMD1	1.59e-03	49	88	3	PF00431
Domain	-	ADIPOQ MMRN2 C1QTNF5	1.69e-03	50	88	3	2.60.120.40
Domain	CUB	CDCP2 C1QTNF5 CSMD1	1.69e-03	50	88	3	SM00042
Domain	CUB	CDCP2 C1QTNF5 CSMD1	2.00e-03	53	88	3	PS01180
Domain	CUB_dom	CDCP2 C1QTNF5 CSMD1	2.46e-03	57	88	3	IPR000859
Domain	AT_hook	KMT2C CECR2	2.52e-03	16	88	2	PF02178
Domain	Tumour_necrosis_fac-like_dom	ADIPOQ MMRN2 C1QTNF5	2.59e-03	58	88	3	IPR008983
Domain	Intermediate_filament_CS	KRT23 NEFH KRT19	3.27e-03	63	88	3	IPR018039
Domain	C1	KMT2C TNS2 STAC	3.58e-03	65	88	3	SM00109
Domain	PE/DAG-bd	KMT2C TNS2 STAC	3.73e-03	66	88	3	IPR002219
Domain	IF	KRT23 NEFH KRT19	4.77e-03	72	88	3	PS00226
Domain	Frizzled_dom	FZD10 C1QTNF5	5.66e-03	24	88	2	IPR020067
Domain	FZ	FZD10 C1QTNF5	5.66e-03	24	88	2	PS50038
Domain	Fz	FZD10 C1QTNF5	5.66e-03	24	88	2	PF01392
Pubmed	Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent.	NEUROD2 NR5A2 SLC30A3 TFAP2C	3.83e-06	39	94	4	30529950
Pubmed	Total and HMW adiponectin is independently associated with B-type natriuretic peptide and anemia in chronic hemodialysis patients.	NPPB ADIPOQ	7.23e-06	2	94	2	23207119
Pubmed	The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor.	ADIPOQ C1QTNF5	7.23e-06	2	94	2	9512423
Pubmed	K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.	SLC4A8 SLC4A10	7.23e-06	2	94	2	38674160
Pubmed	In hemodialysis, adiponectin, and pro-brain natriuretic peptide levels may be subjected to variations in body mass index.	NPPB ADIPOQ	7.23e-06	2	94	2	21838836
Pubmed	Transcription of RORγt in developing Th17 cells is regulated by E-proteins.	TCF3 RORC	7.23e-06	2	94	2	24064669
Pubmed	Metabolomic profiling implicates adiponectin as mediator of a favorable lipoprotein profile associated with NT-proBNP.	NPPB ADIPOQ	7.23e-06	2	94	2	30153838
Pubmed	High adiponectin and increased risk of cardiovascular disease and mortality in asymptomatic older men: does NT-proBNP help to explain this association?	NPPB ADIPOQ	7.23e-06	2	94	2	20505514
Pubmed	Relation between adiponectin and brain natriuretic peptide in healthy pediatric subjects: from birth through childhood.	NPPB ADIPOQ	7.23e-06	2	94	2	22748606
Pubmed	Potential interaction of brain natriuretic peptide with hyperadiponectinemia in preeclampsia.	NPPB ADIPOQ	7.23e-06	2	94	2	22234370
Pubmed	Brain natriuretic peptides in atherosclerotic renal artery stenosis and effects of renal angioplasty.	NPPB ADIPOQ	7.23e-06	2	94	2	24356556
Pubmed	Plasma adiponectin is associated with plasma brain natriuretic peptide and cardiac function in healthy subjects.	NPPB ADIPOQ	7.23e-06	2	94	2	18712036
Pubmed	Association of adiponectin and amino terminal proBNP in peripheral arterial disease.	NPPB ADIPOQ	7.23e-06	2	94	2	17112494
Pubmed	Reciprocal effects of systemic inflammation and brain natriuretic peptide on adiponectin biosynthesis in adipose tissue of patients with ischemic heart disease.	NPPB ADIPOQ	7.23e-06	2	94	2	25060790
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	NCOR2 ZNF469 DROSHA BICRA CECR2 FBF1 PRSS56 DVL2 WRNIP1 HELZ LZTS2 PIP4K2C CSMD1	9.69e-06	1116	94	13	31753913
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	MSX2 NEUROD2 GLI2 NR5A2 RORC ZNF784 ZNF282 TFAP2C ZIC3	1.72e-05	544	94	9	28473536
Pubmed	AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells.	TNS2 IRS1	2.16e-05	3	94	2	30419905
Pubmed	C1-Ten is a protein tyrosine phosphatase of insulin receptor substrate 1 (IRS-1), regulating IRS-1 stability and muscle atrophy.	TNS2 IRS1	2.16e-05	3	94	2	23401856
Pubmed	Epithelial-mesenchymal transition-related gene expression as a new prognostic marker for neuroblastoma.	TCF3 KRT19	2.16e-05	3	94	2	23135478
Pubmed	Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency.	TCF3 RORC	2.16e-05	3	94	2	21325057
Pubmed	Adiponectin improves cardiomyocyte contractile function in db/db diabetic obese mice.	ADIPOQ IRS1	2.16e-05	3	94	2	19057532
Pubmed	TBX1 and Basal Cell Carcinoma: Expression and Interactions with Gli2 and Dvl2 Signaling.	GLI2 DVL2	2.16e-05	3	94	2	31963474
Pubmed	Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma.	DVL2 FZD10	2.16e-05	3	94	2	19137009
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	MSX2 KMT2C TCF3 NEUROD2 ARID3A GLI2 NR5A2 RORC TACC2 TFAP2C	2.26e-05	709	94	10	22988430
Pubmed	Analysis of BCL6-interacting proteins by tandem mass spectrometry.	NCOR2 DROSHA HELZ2 CSMD1	2.48e-05	62	94	4	16147992
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCOR2 RBM15 KRT19 DROSHA FAAP20 HELZ TACC2 LZTS2 PIP4K2C	3.15e-05	588	94	9	38580884
Pubmed	A census of human transcription factors: function, expression and evolution.	MSX2 TCF3 NEUROD2 ZFP36L1 GLI2 NR5A2 RORC ZNFX1 BOLA1 ZNF282 TFAP2C	3.47e-05	908	94	11	19274049
Pubmed	Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/β-catenin signaling through blocking autophagic degradation of dishevelled2.	DVL2 IRS1	4.32e-05	4	94	2	24616100
Pubmed	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.	NCOR2 RBM15	4.32e-05	4	94	2	16129689
Pubmed	Genetic variations in ATP2B1, CSK, ARSG and CSMD1 loci are related to blood pressure and/or hypertension in two Korean cohorts.	CSMD1 ARSG	4.32e-05	4	94	2	19960030
Pubmed	GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population.	BICRA PPP1R13L	4.32e-05	4	94	2	30128886
Pubmed	RORgammaT, a thymus-specific isoform of the orphan nuclear receptor RORgamma / TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoter.	MSX2 RORC	4.32e-05	4	94	2	10602018
Pubmed	A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells.	RYR1 ZIC3	4.32e-05	4	94	2	7931345
Pubmed	Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production.	ADIPOQ IRS1	4.32e-05	4	94	2	26888756
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MSX2 NCOR2 KMT2C ARID3A BICRA KHNYN HELZ2 IRS1 ATG2A ARSG RYR1 TJP3	4.33e-05	1105	94	12	35748872
Pubmed	Prognostic significance of adipocytokines and extracellular matrix activity in heart failure patients with high B-type natriuretic peptide.	NPPB ADIPOQ	7.19e-05	5	94	2	19560452
Pubmed	Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2.	TCF3 PKD2	7.19e-05	5	94	2	16311606
Pubmed	Transcriptome profiling of the Olig2-expressing astrocyte subtype reveals their unique molecular signature.	EFNB3 INKA2	7.19e-05	5	94	2	34296073
Pubmed	Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.	SLC4A8 SLC4A10	7.19e-05	5	94	2	23500099
Pubmed	The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells.	GLI2 DVL2	7.19e-05	5	94	2	27477274
Pubmed	Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma.	GLI2 FUT4	1.08e-04	6	94	2	19487286
Pubmed	Variation of tooth number in mammalian dentition: connecting genetics, development, and evolution.	MSX2 GLI2	1.08e-04	6	94	2	12752768
Pubmed	Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction.	NEFH RYR1	1.08e-04	6	94	2	31804576
Pubmed	Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility.	STAC RYR1	1.08e-04	6	94	2	23818578
Pubmed	Physical and functional interactions between Zic and Gli proteins.	GLI2 ZIC3	1.08e-04	6	94	2	11238441
Pubmed	Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system.	NEFH FUT4	1.08e-04	6	94	2	11804570
Pubmed	Genetic determinants of insulin action in polycystic ovary syndrome.	ADIPOQ IRS1	1.08e-04	6	94	2	15926113
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TCF3 ZFP36L1 DROSHA KHNYN DVL2 WRNIP1 ZNFX1 ATG2A LZTS2 PPP1R13L TJP3	1.14e-04	1038	94	11	26673895
Pubmed	Host PDZ-containing proteins targeted by SARS-CoV-2.	SNX27 PDZD2 TJP3	1.18e-04	35	94	3	33864728
Pubmed	Acute-phase serum amyloid A as a marker of insulin resistance in mice.	ADIPOQ IRS1	1.50e-04	7	94	2	18584041
Pubmed	Cochlear histopathology of the mutant bustling mouse, BUS/Idr.	NEFH CDH23	1.50e-04	7	94	2	8790740
Pubmed	Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus.	KRT19 HS6ST2	1.50e-04	7	94	2	20410206
Pubmed	Structural analysis of the high molecular mass aminoacyl-tRNA synthetase complex. Effects of neutral salts and detergents.	AIMP2 DARS1	2.00e-04	8	94	2	1651330
Pubmed	E protein dosage influences brain development more than family member identity.	TCF3 NEUROD2	2.00e-04	8	94	2	18214987
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF469 FBF1 CDH23 LZTS2	2.09e-04	107	94	4	11347906
Pubmed	Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos.	NR5A2 TFAP2C	2.57e-04	9	94	2	38243114
Pubmed	Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons.	GLI2 FUT4	2.57e-04	9	94	2	18832395
Pubmed	A family of Acrp30/adiponectin structural and functional paralogs.	ADIPOQ C1QTNF5	2.57e-04	9	94	2	15231994
Pubmed	Global gene expression analysis of murine limb development.	MSX2 KMT2C ARID3A TFAP2C	2.94e-04	117	94	4	22174793
Pubmed	CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.	GLI2 ZIC3	3.21e-04	10	94	2	18298960
Pubmed	A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis.	GLI2 ZIC3	3.21e-04	10	94	2	21211521
Pubmed	Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives.	MSX2 ZIC3	3.21e-04	10	94	2	15136147
Pubmed	Medical sequencing of candidate genes for nonsyndromic cleft lip and palate.	MSX2 GLI2	3.21e-04	10	94	2	16327884
Pubmed	Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers.	NEFH EFNB3	3.21e-04	10	94	2	10719886
Pubmed	High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.	IFFO2 TACC2 LZTS2	3.42e-04	50	94	3	29560723
Pubmed	Dissection of the structural organization of the aminoacyl-tRNA synthetase complex.	AIMP2 DARS1	3.91e-04	11	94	2	19131329
Pubmed	Mutations in C1orf194, encoding a calcium regulator, cause dominant Charcot-Marie-Tooth disease.	NEFH RYR1	3.91e-04	11	94	2	31199454
Pubmed	Loss of Zic3 impairs planar cell polarity leading to abnormal left-right signaling, heart defects and neural tube defects.	DVL2 ZIC3	3.91e-04	11	94	2	34274973
Pubmed	Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells.	AIMP2 DARS1	3.91e-04	11	94	2	19289464
Pubmed	Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix.	AIMP2 DARS1	3.91e-04	11	94	2	8449960
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	PCF11 RBM15 FBF1 CDH23 PPP1R13L ARSG	4.53e-04	361	94	6	26167880
Pubmed	Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions.	ADIPOQ C1QTNF5	4.69e-04	12	94	2	18783346
Pubmed	Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain development.	MSX2 NEUROD2	4.69e-04	12	94	2	27048518
Pubmed	An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.	CATSPER1 AIMP2 KRT19 FBF1 PKD2 DVL2 BOLA1	5.00e-04	514	94	7	29892012
Pubmed	Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.	MSX2 GLI2	5.53e-04	13	94	2	25448692
Pubmed	Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.	GLI2 FUT4	5.53e-04	13	94	2	32332736
Pubmed	A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.	CECR2 DVL2	5.53e-04	13	94	2	26989192
Pubmed	Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1).	NEFH RYR1	5.53e-04	13	94	2	30870432
Pubmed	Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein.	AIMP2 DARS1	5.53e-04	13	94	2	9878398
Pubmed	The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development.	SHANK1 NEFH	5.53e-04	13	94	2	32675174
Pubmed	Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development.	CECR2 FZD10	5.53e-04	13	94	2	21246654
Pubmed	Tbx6 controls left-right asymmetry through regulation of Gdf1.	PKD2 FZD10	5.53e-04	13	94	2	29650695
Pubmed	p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance.	AIMP2 DARS1	6.44e-04	14	94	2	12060739
Pubmed	Msx1 and Msx2 promote meiosis initiation.	MSX2 FUT4	6.44e-04	14	94	2	22071108
Pubmed	Developmental changes in cellular and extracellular structural macromolecules in the secondary palate and in the nasal cavity of the mouse.	KRT19 FUT4	6.44e-04	14	94	2	20572855
Pubmed	Cytoplasmic short linear motifs in ACE2 and integrin β3 link SARS-CoV-2 host cell receptors to mediators of endocytosis and autophagy.	SHANK1 SNX27	6.44e-04	14	94	2	33436498
Pubmed	Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization.	DVL2 IRS1	6.44e-04	14	94	2	34674267
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NCOR2 KMT2C TCF3 AIMP2 BICRA GLI2 UVSSA PKD2 LZTS2 CSMD1 INKA2 PDZD2	6.76e-04	1489	94	12	28611215
Pubmed	PDZ-Containing Proteins Targeted by the ACE2 Receptor.	SHANK1 SNX27	7.42e-04	15	94	2	34835087
Pubmed	Teeth. Where and how to make them.	MSX2 GLI2	7.42e-04	15	94	2	10098408
Pubmed	AdipoRon accelerates bone repair of calvarial defect in diet-induced obesity mice.	ADIPOQ CDH23	7.42e-04	15	94	2	36873496
Pubmed	Essential role of MESP1-RING1A complex in cardiac differentiation.	TCF3 ZIC3	7.42e-04	15	94	2	36413948
Pubmed	Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2).	MSX2 GLI2	7.42e-04	15	94	2	22547067
Pubmed	Sonic hedgehog signaling is essential for hair development.	MSX2 GLI2	7.42e-04	15	94	2	9768360
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	FAAP20 KHNYN DVL2 HELZ LZTS2	7.55e-04	263	94	5	34702444
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PCF11 NCOR2 KMT2C RBM15 TCF3 ARID3A AIMP2 BICRA WRNIP1 DARS1	8.04e-04	1103	94	10	34189442
Pubmed	Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis.	NEFH GLI2	8.46e-04	16	94	2	15647317
Pubmed	Msx1 and Msx2 function together in the regulation of primordial germ cell migration in the mouse.	MSX2 FUT4	8.46e-04	16	94	2	27435625
Pubmed	Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation.	NEFH RORC	9.57e-04	17	94	2	19783990
Pubmed	Functional analysis of candidate genes from genome-wide association studies of hearing.	CSMD1 ARSG	9.57e-04	17	94	2	31927188
GeneFamily	UPF1 like RNA helicases	HELZ2 HELZ ZNFX1	5.91e-06	11	61	3	1169
GeneFamily	PDZ domain containing	SHANK1 DVL2 SNX27 PDZD2 TJP3	1.60e-04	152	61	5	1220
GeneFamily	Cadherin related	CLSTN3 CDH23	1.47e-03	17	61	2	24
GeneFamily	Endogenous ligands\|C1q and TNF related	ADIPOQ C1QTNF5	1.65e-03	18	61	2	1372
GeneFamily	Keratins, type I	KRT23 KRT19	4.00e-03	28	61	2	608
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHANK1 ZFP36L1 SLC4A10 KIAA0087 RORC STAC PDZD2	5.65e-08	163	94	7	00e791358a7eb6c3e95f87afe22153845012e4a1
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SHANK1 ZFP36L1 SLC4A10 KIAA0087 RORC STAC PDZD2	1.29e-07	184	94	7	479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT19 PLK5 LOXL4 CSMD1 PPP1R13L RYR1	1.65e-06	170	94	6	0cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT19 PLK5 LOXL4 CSMD1 PPP1R13L RYR1	1.65e-06	170	94	6	2d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SHANK1 SLC4A10 KIAA0087 RORC STAC PDZD2	1.89e-06	174	94	6	5e6050d20a5b27640f6a200441125b8ceba123c8
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHANK1 ZFP36L1 SLC4A10 KIAA0087 RORC STAC	2.69e-06	185	94	6	7d6954bb04368ec62b284ba6c3021a15fbdfdee6
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 ZFP36L1 KRT19 HS6ST2 NR5A2 SLC39A5	2.86e-06	187	94	6	9aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	SLC4A10 IFFO2 KIAA0087 RORC STAC PDZD2	3.13e-06	190	94	6	0c7eb8f4f2926af01bf44d5c9f239be7b81c67fe
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SHANK1 SLC4A10 KIAA0087 RORC STAC PDZD2	3.33e-06	192	94	6	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	E16.5-samps-Mesenchymal-Pericyte\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TMEM160 LOXL4 C1QTNF5 FUT4 PDZD2	1.56e-05	148	94	5	e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCell	E16.5-samps-Mesenchymal-Pericyte-pericyte_A\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TMEM160 LOXL4 C1QTNF5 FUT4 PDZD2	1.56e-05	148	94	5	c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCell	10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3\|bone_marrow / Manually curated celltypes from each tissue	SLC4A10 IFFO2 KIAA0087 RORC STAC	1.95e-05	155	94	5	83430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A10 AGMAT CSMD1 RYR1 PDZD2	2.79e-05	167	94	5	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KMT2C KRT19 WRNIP1 RORC IRS1	2.87e-05	168	94	5	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	SHANK1 SLC4A10 RORC STAC PDZD2	2.87e-05	168	94	5	d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CATSPER1 CDH23 CSMD1 CCDC144NL RYR1	2.95e-05	169	94	5	e3100eb587005e160bd0b7990fa57ec49765133d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	SHANK1 SLC4A10 RORC STAC PDZD2	3.04e-05	170	94	5	97df5ffb328196c46568975d2d97722bcc753bf5
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 NPPB PPFIA4 PRSS56 FZD10	3.49e-05	175	94	5	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SHANK1 SLC4A10 KIAA0087 RORC PDZD2	3.89e-05	179	94	5	bc95c3e7edc5fc6fc913b09f087d221df64c6f48
ToppCell	droplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 IFFO2 CDH23 RORC SLC30A3	3.89e-05	179	94	5	d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCell	facs-Pancreas-Exocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 ZFP36L1 KRT19 NR5A2 SLC39A5	4.20e-05	182	94	5	45faefd7cbeac84d2c58650530b902af6ce921f8
ToppCell	droplet-Thymus-nan-18m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 PPFIA4 NR5A2 AGMAT CDC42EP5	4.20e-05	182	94	5	f6717e97e87513384149800c9fd8dea821ab9393
ToppCell	droplet-Thymus-nan-18m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 PPFIA4 NR5A2 AGMAT CDC42EP5	4.20e-05	182	94	5	c33b0d532822186a1e8e645500347972468718c0
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	ZFP36L1 SLC4A10 KIAA0087 RORC STAC	4.43e-05	184	94	5	d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KRT19 CECR2 RORC PPP1R13L TJP3	4.54e-05	185	94	5	c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KRT19 CECR2 RORC PPP1R13L TJP3	4.66e-05	186	94	5	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	droplet-Thymus-nan-18m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT19 PPFIA4 NR5A2 PKD2 CDC42EP5	4.78e-05	187	94	5	ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ZFP36L1 SLC4A10 KIAA0087 RORC PDZD2	4.78e-05	187	94	5	f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCell	(6)_ILC\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	SLC4A10 MMRN2 KIAA0087 RORC STAC	4.91e-05	188	94	5	de7cb273899d0e0748c85f45c6b5e7f0642ab057
ToppCell	(6)_ILC\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	SLC4A10 MMRN2 KIAA0087 RORC STAC	4.91e-05	188	94	5	f4734d5b703678670ece204a0519cf015e180a6e
ToppCell	ILEUM-non-inflamed-(6)_ILC3\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZFP36L1 SLC4A10 KIAA0087 RORC STAC	5.29e-05	191	94	5	6eaf72b41084404bee0db04e4605db745a74995f
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KRT19 NR5A2 MMRN2 CDC42EP5 ZIC3	5.56e-05	193	94	5	3f8280ef849d95b2fcea5e6824b95a07febc96d0
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KRT23 SLC4A8 ADIPOQ KRT19 CDC42EP5	5.69e-05	194	94	5	e0228f593c3493175962a4817500d4337ddc4e88
ToppCell	ILEUM-inflamed-(6)_ILC3\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZFP36L1 SLC4A10 KIAA0087 RORC STAC	5.83e-05	195	94	5	c6968da7d2b60c2163e1ff0ffa41340e1ec1d2ed
ToppCell	ILEUM-non-inflamed-(6)_ILC\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZFP36L1 SLC4A10 KIAA0087 RORC STAC	6.12e-05	197	94	5	76a233eb9611d24b9bb9f4359c26606332a3c29e
ToppCell	Thalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MSX2 GLI2 KCNE5 RORC	6.25e-05	101	94	4	1d74f6b30d23e942f26fc57665b5c533ff0c089f
ToppCell	Thalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	MSX2 GLI2 KCNE5 RORC	6.25e-05	101	94	4	578946c048084f48a74d4352743017f04039d5e8
ToppCell	Thalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	MSX2 GLI2 KCNE5 RORC	6.25e-05	101	94	4	8a3b8abe06a8c5b546ce40c9429401058fe671d7
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KRT23 KRT19 KIF19 TFAP2C TJP3	6.27e-05	198	94	5	6712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KRT23 KRT19 KIF19 TFAP2C TJP3	6.42e-05	199	94	5	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KRT23 KRT19 KIF19 TFAP2C TJP3	6.42e-05	199	94	5	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	NS-moderate-d_16-33-Epithelial\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KRT23 KRT19 CDC42EP5 TACC2 TJP3	6.42e-05	199	94	5	aa2b51940115c22768c0d7493b4b60d41df3f376
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KRT23 SLC4A8 KRT19 KIF19 TFAP2C	6.58e-05	200	94	5	cf191104484bfb2b9f87de416b9453135f8833c1
ToppCell	Transverse-(3)_ILC-(30)_ILC\|Transverse / shred on region, Cell_type, and subtype	ZFP36L1 SLC4A10 KIAA0087 RORC STAC	6.58e-05	200	94	5	528520dc98775aca6cc7568fedf5906ea55e0bea
ToppCell	Transverse-(3)_ILC\|Transverse / shred on region, Cell_type, and subtype	ZFP36L1 SLC4A10 KIAA0087 RORC STAC	6.58e-05	200	94	5	c1ad7cb012e1c8911e417f7d64ca662c4f5010e0
ToppCell	Transverse-ILC\|Transverse / Region, Cell class and subclass	ZFP36L1 SLC4A10 KIAA0087 RORC STAC	6.58e-05	200	94	5	eb04d6ad2270d3d9ac3d1fae1bb9bedc6fca38fe
ToppCell	Transverse-ILC-ILC\|Transverse / Region, Cell class and subclass	ZFP36L1 SLC4A10 KIAA0087 RORC STAC	6.58e-05	200	94	5	60ec185df2f1989bf8febf75b11c46a576829be3
ToppCell	LPS_IL1RA-Epithelial_airway\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KRT23 SLC4A8 KRT19 KIF19 TFAP2C	6.58e-05	200	94	5	a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCell	Thalamus-Macroglia-ASTROCYTE\|Thalamus / BrainAtlas - Mouse McCarroll V32	MSX2 GLI2 KCNE5 RORC	1.26e-04	121	94	4	c3a4dfd19b7e8654e859df605d55155b530ad009
ToppCell	Thalamus-Macroglia-ASTROCYTE-Gja1\|Thalamus / BrainAtlas - Mouse McCarroll V32	MSX2 GLI2 KCNE5 RORC	1.26e-04	121	94	4	c3efd44bd01c12ef8c7ce4cc351af1540b70a63c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nts\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EFNB3 PRSS56 CDC42EP5 STAC	1.52e-04	127	94	4	ace2944328529fa029ee56c7ad3b0f283511d3bb
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)\|Striatum / BrainAtlas - Mouse McCarroll V32	ZNF469 NEUROD2 BICRA SLC30A3	1.56e-04	128	94	4	7e3f5cea91af005f08d8e9340fb8630bf1c887c3
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Striatum / BrainAtlas - Mouse McCarroll V32	ZNF469 NEUROD2 BICRA SLC30A3	1.56e-04	128	94	4	a876303c852db2af9418d1a1711d7c950805018a
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-\|Striatum / BrainAtlas - Mouse McCarroll V32	ZNF469 NEUROD2 BICRA SLC30A3	1.56e-04	128	94	4	388062f840fd04cb8087f27a9a78e7a192920e3e
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature\|E16.5-samps / Age Group, Lineage, Cell class and subclass	SLC4A8 HS6ST2 PPFIA4 LOXL4	1.61e-04	129	94	4	5e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NR5A2 HELZ2 MMRN2 ZIC3	1.71e-04	131	94	4	d5bc40cd585582856881081b7130dec3515b4ae0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CECR2 TACC2 STAC ARSG	2.33e-04	142	94	4	5b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNE5 FUT4 ZNF282 INKA2	2.39e-04	143	94	4	9836a040a2ebcf6f05431e658a7b8fd566621452
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KCNE5 FUT4 ZNF282 INKA2	2.39e-04	143	94	4	4622c221b5d2d4cd4f37e4f81662e073924e1507
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CECR2 SLC4A10 RORC ZNF282	2.59e-04	146	94	4	bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SLC4A10 KIAA0087 STAC PDZD2	2.59e-04	146	94	4	40fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	NR5A2 AGMAT FUT4 SLC39A5	2.59e-04	146	94	4	e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	NR5A2 AGMAT FUT4 SLC39A5	2.80e-04	149	94	4	92a8931a51db619fb5f0638d319c02e7838f6559
ToppCell	3'_v3-blood-Lymphocytic_Invariant-Inducer-like\|blood / Manually curated celltypes from each tissue	SHANK1 SLC4A10 RORC STAC	2.80e-04	149	94	4	75422e1a22736375e9ef439db0b2a5efa3f653a3
ToppCell	LPS-antiTNF-Endothelial-Epi-like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPFIA4 UVSSA SLC30A3 TFAP2C	2.87e-04	150	94	4	9cb3332924bd67c966873343c14445e30d3f384f
ToppCell	droplet-Fat-Scat-21m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT19 PPFIA4 SLC30A3 RYR1	2.94e-04	151	94	4	79827a76c675dcb82f59c0a45d0f962b02d5bfd6
ToppCell	mild_COVID-19_(asymptomatic)-MAIT\|World / disease group, cell group and cell class (v2)	KRT23 SLC4A10 RORC CSMD1	3.09e-04	153	94	4	2b4c69f6db17927d6506a645ac058133e60b0103
ToppCell	Leuk-UTI-Lymphocyte-T_NK-MAIT\|Leuk-UTI / Disease, Lineage and Cell Type	SLC4A10 RORC CCDC144NL TJP3	3.09e-04	153	94	4	ac3a1d1b5bf6009df818fd757dad7382d95c60dc
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLK5 KIF19 IFFO2 RORC	3.09e-04	153	94	4	20786807bba3bcd70ce744f8b6454e064199ed9f
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|390C / Donor, Lineage, Cell class and subclass (all cells)	RORC ZNF282 STAC CHRNE	3.25e-04	155	94	4	98d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NEUROD2 PIP4K2C SLC30A3 INKA2	3.66e-04	160	94	4	d8241404d775f9a709abdf17988f36293fcf4c58
ToppCell	facs-Thymus-Flowthrough-24m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 MSX2 KRT19 CDC42EP5	3.84e-04	162	94	4	ebce09d96e02820ce7d33ad3f417586f96efed76
ToppCell	facs-Thymus-Flowthrough-24m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 MSX2 KRT19 CDC42EP5	3.84e-04	162	94	4	96c8ed9d9cb1cf4175c2f41a6e4ebe02a378044c
ToppCell	facs-Thymus-Flowthrough-24m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 MSX2 KRT19 CDC42EP5	3.84e-04	162	94	4	b4adb9c053e02e71b0f1a6e7ab6dddc34a7245e0
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RSAD1 PPFIA4 CDH23 CHRNE	3.93e-04	163	94	4	f558ad9569e5137e62a601ba4f073e69ed8f8650
ToppCell	LPS_only-Epithelial_airway-Club_cells-Airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KRT23 KRT19 TFAP2C TJP3	4.02e-04	164	94	4	b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCell	LPS_only-Epithelial_airway-Club_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KRT23 KRT19 TFAP2C TJP3	4.02e-04	164	94	4	c5b2001280a43da855017361a3f6071a0e492848
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-ILC3\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC4A10 RORC STAC CCDC144NL	4.02e-04	164	94	4	631ec9f54475dcc9d6b1c5bf6917e7fda4671034
ToppCell	LPS_only-Epithelial_airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KRT23 KRT19 TFAP2C TJP3	4.02e-04	164	94	4	56e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KRT23 KRT19 TFAP2C TJP3	4.11e-04	165	94	4	1a114eacaab598f755a173a3fed842ba91f689dd
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KRT23 KRT19 TFAP2C TJP3	4.11e-04	165	94	4	9cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	SHANK1 SLC4A10 KIAA0087 RORC	4.21e-04	166	94	4	773673a5d0430640439845b264740bfbbdad0cb2
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HS6ST2 LOXL4 SLC39A5 ARSG	4.31e-04	167	94	4	ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT19 NR5A2 SLC39A5 TJP3	4.31e-04	167	94	4	720dc5855c856b478b5ca90156b30bfcc5518d60
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	SHANK1 SLC4A10 KIAA0087 RORC	4.31e-04	167	94	4	3ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT19 CECR2 SLC39A5 ARSG	4.31e-04	167	94	4	3c06894fc6177f3c204094719904da42f08b9af8
ToppCell	3'_v3-Lung-Lymphocytic_Invariant-Inducer-like\|Lung / Manually curated celltypes from each tissue	SHANK1 ZFP36L1 SLC4A10 RORC	4.40e-04	168	94	4	b9bde6f542d730682d34a80e1f7f1609e5c699c7
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-ILC3\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC4A10 KIAA0087 RORC STAC	4.40e-04	168	94	4	4f2f78e14f044b535847bcdbbcec8c0fc8529870
ToppCell	droplet-Kidney-nan-18m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HS6ST2 LOXL4 SLC39A5 ARSG	4.50e-04	169	94	4	f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L1 SLC4A10 RORC STAC	4.50e-04	169	94	4	d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SHANK1 KIAA0087 RORC STAC	4.60e-04	170	94	4	6c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCell	droplet-Lung-nan-18m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 CLSTN3 KRT19 PPP1R13L	4.71e-04	171	94	4	3b02dc5609f5bcd055b532bb4631d2a7183804e9
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT23 NEUROD2 KRT19 KIF19	4.71e-04	171	94	4	c54dcad75fc378da1943009d7dd872b39ea337c0
ToppCell	droplet-Lung-nan-21m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 IFFO2 CDH23 SLC30A3	4.71e-04	171	94	4	159ce6d5513008532dd7785b915b3fe7440cc4b2
ToppCell	droplet-Lung-nan-18m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT23 CLSTN3 KRT19 PPP1R13L	4.71e-04	171	94	4	88309bfb1cf427783c853dfd6709cd5edc9074b9
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFP36L1 SLC4A10 RORC STAC	4.71e-04	171	94	4	6ab7f103cbdbd49ef687cbb8a42ddc5517af0f7f
ToppCell	3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like\|bone_marrow / Manually curated celltypes from each tissue	ZFP36L1 SLC4A10 RORC CCDC107	4.71e-04	171	94	4	2977cffc146470733b5cfd8a1aa80d9346d4804d
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	BICRA CECR2 RORC PPP1R13L	4.81e-04	172	94	4	d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARID3A KRT19 CSMD1 SLC39A5	4.92e-04	173	94	4	b75353fcbc9f8cdb21d4f10ddbc93a83fd797a3c
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT23 NEUROD2 KRT19 KIF19	4.92e-04	173	94	4	cc2e489b91562a0c6fe863e2f796f4a7d2ca27dd
Computational	Genes in the cancer module 139.	MSX2 KRT19 SLC4A10 TFAP2C TJP3	4.50e-05	79	54	5	MODULE_139
Computational	Genes in the cancer module 180.	MSX2 KRT19 SLC4A10 TFAP2C TJP3	3.13e-04	119	54	5	MODULE_180
Disease	glucagon-like peptide-1 measurement	BICRA CSMD1	3.98e-04	10	89	2	EFO_0008465
Disease	cardiac troponin T measurement	ZFP36L1 PPFIA4 CECR2 CDH23 ADGRD2	5.38e-04	219	89	5	EFO_0005043
Disease	metabolite measurement, body weight gain	KIF19 TACC2	5.82e-04	12	89	2	EFO_0004566, EFO_0004725
Disease	Connective Tissue Diseases	ZNF469 PKD2	6.87e-04	13	89	2	C0009782
Disease	Kawasaki disease (is_marker_for)	NPPB ADIPOQ	8.00e-04	14	89	2	DOID:13378 (is_marker_for)
Disease	biliary atresia (is_marker_for)	ADIPOQ GLI2	8.00e-04	14	89	2	DOID:13608 (is_marker_for)
Disease	polycystic kidney disease (implicated_via_orthology)	NPPB PKD2	8.00e-04	14	89	2	DOID:0080322 (implicated_via_orthology)
Disease	anemia (implicated_via_orthology)	SLC4A8 SLC4A10	9.21e-04	15	89	2	DOID:2355 (implicated_via_orthology)
Disease	atherosclerosis (is_implicated_in)	NPPB ADIPOQ	1.05e-03	16	89	2	DOID:1936 (is_implicated_in)
Disease	longevity	UVSSA ZNFX1 C1QTNF5 CSMD1 INKA2	1.71e-03	284	89	5	EFO_0004300

Protein segments in the cluster

Peptide	Gene	Start	Entry
RSHAAPSPGHGGKHG	CDRT15L2	171	A8MXV6
GAGLPSHHGRPAGLL	TFAP2C	111	Q92754
HSLHRRVSGAGGPPG	CLSTN3	871	Q9BQT9
NHGRAHGPTGFGLAP	CATSPER1	86	Q8NEC5
PGIPVNGHRHGGDFG	CSMD1	876	Q96PZ7
APGAHSHGLDLGVPG	CXorf49;	31	A8MYA2
HPGHNGAPGRDGRDG	ADIPOQ	46	Q15848
LGGPGPTRGHHYCGS	CDCP2	206	Q5VXM1
PGHRVLFHPNSGAAG	ARSG	401	Q96EG1
HSSTGAVGGHPRGPG	CCDC144NL	176	Q6NUI1
RGHPGSSRGGRQGYH	FLG	3111	P20930
GGHAVPPGSETHFRV	BOLA1	56	Q9Y3E2
PGDHSPGQGSLRFRH	CDH23	3256	Q9H251
GRGFSHPLHCGGTPS	CECR2	626	Q9BXF3
EHGAGGHRTGGPSRL	DVL2	171	O14641
STGGAPNLRAHPGLH	DVL2	651	O14641
YGGRDFGPHPGHRAR	ATG2A	1431	Q2TAZ0
FGPHPGHRARTGLSG	ATG2A	1436	Q2TAZ0
PGVIRRHHGGATDGP	CHRNE	211	Q04844
SVVGASVGGHRHPPG	RBM15	271	Q96T37
DHGAPARGSPHSEGG	NCOR2	2186	Q9Y618
GPGVAFRAPSIHGGS	KRT19	26	P08727
GPVHCSHGGGRFLAG	LOXL4	511	Q96JB6
RPHGFRFGFPGGSHG	KMT2C	2476	Q8NEZ4
SSPGGHLPSHGSGRG	LZTS2	241	Q9BRK4
GPGRSYRLLHGAGGH	FAAP20	96	Q6NZ36
GSGHFPFPGTGEHRR	INKA2	256	Q9NTI7
PAGLAVHRGGHFDTP	HECA	326	Q9UBI9
GGRHIGGPRSTLKHP	KIAA0087	76	Q14695
GPGTGQLVFGGHHRT	MMRN2	881	Q9H8L6
HLGGAGQGPRPLHSG	FUT4	66	P22083
GRGGPFVDGVHSRSH	PPFIA4	496	O75335
HHRGNASGLGAGPRP	KCNE5	21	Q9UJ90
SHFGREGHPPHSLGR	PDZD2	2231	O15018
LDGGRTGRHPHGPAT	PLK5	221	Q496M5
RSFPRAPTVHGGAGG	KRT23	26	Q9C075
GPRRGSDGPTYGHGH	GLI2	936	P10070
FLGGRSHPLGSPGSA	NPPB	21	P16860
QTAGRARGGAPPHAG	GGN	211	Q86UU5
GGGSGGRLPGHRHSA	IRS1	561	P35568
PGTGFLPGDTARHHR	OSGEP	36	Q9NPF4
QTHGRGSPIPYGLGH	HELZ	1241	P42694
GEAPSRAVGHHGDGP	KIF19	851	Q2TAC6
HRGQPVGGLRFEGPH	PCF11	881	O94913
HGPSGAAIRFDGPHG	PCF11	921	O94913
LGAPFAPLHGGGSLH	NEFH	11	P12036
GPGRGGCDNPGKFHH	FZD10	186	Q9ULW2
EGLHLAGTAGHPPSG	FBF1	446	Q8TES7
GTPGHHGSQGLPGRD	C1QTNF5	36	Q9BXJ0
LRAHPGNAAHPGSGA	CCDC107	31	Q8WV48
PLGDFRHTLHVGRGG	CDC42EP5	26	Q6NZY7
GGGSHPQHYGRLPGT	IFFO2	146	Q5TF58
GGGFCVHREPPGAHG	KHNYN	316	O15037
RAGPPRGVSHGFHTR	HS6ST2	51	Q96MM7
GGSHRARPGPVHFID	ARRDC1-AS1	31	Q9H2J1
GHHLHGGGGSPPDTR	HELZ2	1581	Q9BYK8
PIAASSEGHRLPGHG	BICRA	1211	Q9NZM4
SRHPGPGSFGRGGSL	EFNB3	261	Q15768
GHPRHGLPGVGVTTS	RYR1	1756	P21817
IISRLFHRHGGPGPG	PPP1R13L	546	Q8WUF5
GPGAGSHPFGVHNSR	POM121L1P	6	Q3SYA9
AHGRIVGGSAAPPGA	PRSS56	101	P0CW18
GIGGYIHSHRPLGPG	PIP4K2C	331	Q8TBX8
LSGHGAREAHSPGPL	MSX2	81	P35548
HGLTPIGAGLPDRHG	NR5A2	16	O00482
PGAHGRFMPQGAGGH	RSAD1	301	Q9HA92
SFHPGRGCPRGRGGH	DROSHA	11	Q9NRR4
DLPASAGHPRAGGGA	UVSSA	256	Q2YD98
GVGARPAAGLFHPGR	AGMAT	16	Q9BSE5
RGHAGYPAPGIVAHG	MRGPRG-AS1	21	Q2M3A8
IDSFRFGAPPHAGGG	DARS1	456	P14868
PHGGHSGPELQRTGR	SLC4A8	436	Q2Y0W8
LPHAQEGRHAGPGGL	SLC39A5	266	Q6ZMH5
GLGTGAAPGPRLRHS	SHANK1	1271	Q9Y566
RAGARGLGAGHPVPS	ADGRD2	231	Q7Z7M1
HGRSYGPAPGAGHVQ	AIMP2	31	Q13155
RAAAAGLGHPASPGG	ARID3A	66	Q99856
FPGLGVGSFGAPRHH	ZIC3	11	O60481
VGTPAGGGFPRRHSV	ZFP36L1	41	Q07352
HRHPGLGELGQGPDS	RORC	236	P51449
GGRHAGLVGGSHPED	TCF3	436	P15923
HFGGPQGRLCHVPRG	UFSP1	26	Q6NVU6
EPHGGHSGPELQRTG	SLC4A10	466	Q6U841
PARAGLHPGGKAHAF	STAC	96	Q99469
GAPGYSRPGHIHIGR	GPLD1	401	P80108
GEGIHPSAPHRNGGG	SNX27	6	Q96L92
GDFAHTGVPGHVPRS	TACC2	1616	O95359
ARSRGLGGYHGAGHP	PKD2	136	Q13563
LGGYHGAGHPSGRRR	PKD2	141	Q13563
NALRGGASHPGRHPR	ZNFX1	41	Q9P2E3
AGPPHSHGSRGAEYA	SLC30A3	201	Q99726
AGGHLHPTAGRPGFE	ZNF469	1811	Q96JG9
AATAFGASGGGRPHP	WRNIP1	196	Q96S55
GASGGGRPHPRALAA	WRNIP1	201	Q96S55
DTLHPGPGQSHARGG	TJP3	506	O95049
GGARGSFAPGHGPRA	TMEM160	31	Q9NX00
TVGGGPHLGVYPGHR	TNS2	571	Q63HR2
KDHLRVHSGGPGPGA	ZNF282	646	Q9UDV7
QRTHFHGPGPGLGDS	ZNF784	271	Q8NCA9
ALPGSRPTGHGLVFG	NEUROD2	331	Q15784