Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoincreased eosinophil cell number

FZD1 FBXW8 RASAL3 NFATC2IP

4.10e-05178164MP:0005011
MousePhenodecreased circulating interleukin-4 level

RASAL3 NFATC2IP

1.65e-0417162MP:0008603
MousePhenoabnormal eosinophil cell number

FZD1 FBXW8 RASAL3 NFATC2IP

1.66e-04255164MP:0002602
MousePhenoabnormal eosinophil morphology

FZD1 FBXW8 RASAL3 NFATC2IP

1.78e-04260164MP:0005061
DomainNAP

TSPYL6 TSPYL1

2.50e-0417262PF00956
DomainNAP_family

TSPYL6 TSPYL1

2.50e-0417262IPR002164
Pubmed

Murine and human TSPYL genes: novel members of the TSPY-SET-NAP1L1 family.

TSPYL6 TSPYL1

6.71e-0722929730615
Pubmed

A novel SERPINE1-FOSB fusion gene results in transcriptional up-regulation of FOSB in pseudomyogenic haemangioendothelioma.

SERBP1 FOSB

6.71e-07229224374978
Pubmed

TSPY expression is variably altered in transgenic mice with testicular feminization.

TSPYL6 TSPYL1

2.01e-06329218401008
Pubmed

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.

RBM15 PSMD8 EIF3A

6.29e-064329334672947
Pubmed

Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.

PSMD8 FBXW8 EIF3A SERBP1 KIF22

2.68e-054322957671812
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

RBM15 PSMD8 EIF3A SERBP1 TSPYL1 KIF22

1.28e-0497129633306668
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

CCAR1 RBM15 PSMD8 SERBP1

2.19e-0436029433111431
Pubmed

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.

CCAR1 RBM15 EIF3A NFATC2IP

3.35e-0440329435253629
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

CCAR1 RBM15 RP9 EIF3A SERBP1

4.97e-0480729522681889
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

CCAR1 RBM15 EIF3A SERBP1 TSPYL1

6.19e-0484729535850772
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

PSMD8 FBXW8 NFATC2IP FOSB KIF22

6.52e-0485729525609649
Cytoband19q13.32

BLOC1S3 FOSB

1.01e-037429219q13.32

Protein segments in the cluster

PeptideGeneStartEntry
RRVPRRRLPSRRRED

LINC00242

16

Q5T6M2
PGERERPRRRVARED

C9orf50

121

Q5SZB4
IICRRRWREPPPRLL

C8orf86

76

Q6ZUL3
RERERSPRRVRRVVP

CCAR1

346

Q8IX12
PERVVERRRRPRDSP

ATP13A1

886

Q9HD20
RELRGLPPPRPRERE

AHI1-DT

171

P0C7V0
RLRRRSVRPGVVVPR

ANKRD33B

411

A6NCL7
RPDEERPLRRPRPVQ

RASAL3

801

Q86YV0
RDPVPRRSPRWRRAV

RBM15

6

Q96T37
GKIIDRRPERRPPRE

SERBP1

121

Q8NC51
PPARRDVLPRARVSR

CDH24

716

Q86UP0
RRRPEAAERRARRPE

FBXW8

26

Q8N3Y1
TRRPPPARVRVAVRL

KIF22

36

Q14807
RPARRRPAREERERA

FAM171A2

696

A8MVW0
RPARARPRRPREETL

FOSB

136

P53539
RRRPPVDPRRLARQL

FZD1

41

Q9UP38
REPSLRPDDDRVPRR

EIF3A

946

Q14152
LRPRIRPRRDHRPEK

GAS2L2

776

Q8NHY3
RRRRPLRRPETVVPG

BLOC1S3

6

Q6QNY0
DQEPRPRRRRPGRSI

ENGASE

36

Q8NFI3
RRRRRFVPVPLPVVE

COL5A3

1496

P25940
PRRRKIPLLPRRRGE

nan

156

A6NNC1
RRPREPPEQELQRRR

RP9

16

Q8TA86
EDPRRPRLRERAARL

NKX1-2

96

Q9UD57
GPPREPVRRRRRLVL

NFATC2IP

101

Q8NCF5
PVRRRRRLVLDPGEA

NFATC2IP

106

Q8NCF5
RPRTVPKRQIELRPR

PROB1

201

E7EW31
REGVRRARRRPLREP

TSPYL1

411

Q9H0U9
RARRRPLREPVEIPR

TSPYL1

416

Q9H0U9
RRRLVREPVEIPRPF

TSPYL6

391

Q8N831
RAPRAPPRERRRATR

PSMD8

6

P48556
RPRRRDPRRRRTPAL

WWC2-AS2

91

Q96NR7
IRRRRVRDLQDPPPQ

UNC13D

21

Q70J99