Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainGPX_AS

GPX6 GPX3

2.11e-047602IPR029759
DomainGLUTATHIONE_PEROXID_2

GPX6 GPX3

2.81e-048602PS00763
DomainGLUTATHIONE_PEROXID_1

GPX6 GPX3

2.81e-048602PS00460
DomainGlutathione_peroxidase

GPX6 GPX3

2.81e-048602IPR000889
DomainGLUTATHIONE_PEROXID_3

GPX6 GPX3

2.81e-048602PS51355
DomainGPX_CS

GPX6 GPX3

2.81e-048602IPR029760
DomainGSHPx

GPX6 GPX3

2.81e-048602PF00255
DomainGlyco_hydro_47

USF3 EDEM2

2.81e-048602IPR001382
DomainLeu-rich_rpt_4

LRR1 NLRC5

4.49e-0410602IPR025875
DomainLRR_4

LRR1 NLRC5

4.49e-0410602PF12799
Domain-

ZEB1 ARGFX PITX1 LBX2 MYBL2

2.13e-032836051.10.10.60
DomainArfGap

AGAP5 AGAP2

3.90e-0329602SM00105
DomainArfGap

AGAP5 AGAP2

3.90e-0329602PF01412
DomainARFGAP

AGAP5 AGAP2

3.90e-0329602PS50115
DomainArfGAP

AGAP5 AGAP2

3.90e-0329602IPR001164
DomainLRR

LRR1 NLRC5 XRRA1 LRRC2

3.97e-03201604PS51450
DomainHomeodomain-like

ZEB1 ARGFX PITX1 LBX2 MYBL2

4.23e-03332605IPR009057
DomainAnk_2

AGAP5 ANK3 MYO16 AGAP2

5.03e-03215604PF12796
DomainLRR_1

LRR1 NLRC5 XRRA1 LRRC2

5.37e-03219604PF00560
DomainHomeobox

ZEB1 ARGFX PITX1 LBX2

6.77e-03234604PF00046
DomainHOMEOBOX_1

ZEB1 ARGFX PITX1 LBX2

6.97e-03236604PS00027
DomainHOX

ZEB1 ARGFX PITX1 LBX2

7.07e-03237604SM00389
DomainHOMEOBOX_2

ZEB1 ARGFX PITX1 LBX2

7.28e-03239604PS50071
DomainHomeobox_dom

ZEB1 ARGFX PITX1 LBX2

7.28e-03239604IPR001356
Domain-

AGAP5 ANK3 MYO16 AGAP2

8.27e-032486041.25.40.20
DomainANK

AGAP5 ANK3 MYO16 AGAP2

8.62e-03251604SM00248
DomainANK_REPEAT

AGAP5 ANK3 MYO16 AGAP2

8.86e-03253604PS50088
DomainAnkyrin_rpt-contain_dom

AGAP5 ANK3 MYO16 AGAP2

8.98e-03254604IPR020683
DomainANK_REP_REGION

AGAP5 ANK3 MYO16 AGAP2

8.98e-03254604PS50297
Domain-

LRP5 ALK

9.59e-03466024.10.400.10
DomainAnkyrin_rpt

AGAP5 ANK3 MYO16 AGAP2

9.98e-03262604IPR002110
PathwayREACTOME_DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES

GPX6 GPX3 NCF4

1.21e-0435393MM14944
PathwayREACTOME_DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES

GPX6 GPX3 NCF4

1.43e-0437393M27244
PathwayREACTOME_SIGNALING_BY_RNF43_MUTANTS

LRP5 RNF43

2.07e-048392M27433
PathwayKEGG_MEDICUS_REFERENCE_GLUTATHIONE_BIOSYNTHESIS

GPX6 GPX3

4.04e-0411392M47926
Pubmed

A census of human transcription factors: function, expression and evolution.

KLF11 USF3 ZEB1 ARGFX PITX1 BACH1 MLLT3 LBX2 ZC3H3 MYBL2

5.92e-06908641019274049
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

IGHA1 PLCH1 ZC3H3

1.68e-052764326544073
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DACT1 BTBD7 TTLL4 PITX1 NLRC5 LRP5 WNK1 CNTROB RNF43 MYBL2

3.21e-051105641035748872
Pubmed

Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.

TTLL4 SENP3

3.32e-05564220442285
Pubmed

HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells.

GPX6 GPX3

6.96e-05764215910762
Pubmed

Human immunodeficiency virus type 1 Tat protein impairs selenoglutathione peroxidase expression and activity by a mechanism independent of cellular selenium uptake: consequences on cellular resistance to UV-A radiation.

GPX6 GPX3

6.96e-05764211368344
Pubmed

Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice.

GPX6 GPX3

9.27e-05864210652368
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP5 AGAP2

1.19e-04964212640130
Pubmed

Glutathione depletion associated with the HIV-1 TAT protein mediates the extracellular appearance of acidic fibroblast growth factor.

GPX6 GPX3

1.19e-0496429501919
Pubmed

Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor.

WNK1 MYBL2

2.17e-041264212748276
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP5 AGAP2

2.99e-041464222453919
Pubmed

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.

ZEB1 SENP3 MLLT3

3.37e-047364322094256
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

PDE3A PCARE PLCH1 GOLGB1

9.25e-0423464436243803
Pubmed

Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development.

KANSL1L WNK1

1.22e-032864238324473
Pubmed

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.

PITX1 WNK1

1.22e-032864224836286
Pubmed

Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.

GPX6 GPX3

1.40e-033064220200426
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP5 AGAP2

6.36e-04174021291
GeneFamilySelenoproteins

GPX6 GPX3

1.39e-0325402890
GeneFamilyOlfactory receptors, family 5

OR5A2 OR5AP2 OR5F1

1.93e-03112403152
GeneFamilyAnkyrin repeat domain containing

AGAP5 ANK3 MYO16 AGAP2

1.96e-03242404403
GeneFamilyArfGAPs

AGAP5 AGAP2

2.41e-0333402395
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-Uncommitted_AE_Progenitor|E18.5-samps / Age Group, Lineage, Cell class and subclass

EFCAB6 ANK3 ALK RNF43 MYO16

9.43e-071236455f002f5180fe47fe57ab888b5f0319df99ab2c59
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TICRR KLF11 PDE3A KIAA0232 B3GNT3

4.89e-061726458a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARGFX IGHA1 SENP3 NCF4

5.36e-05143644360a2ea8b64e3b9084f4c4cb8beb0d44106b9edb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARGFX IGHA1 SENP3 NCF4

5.36e-05143644605532fc0f32979b306cbb58f8796df7d6b24828
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARGFX IGHA1 SENP3 NCF4

5.36e-051436445cc59deb5a8af8095c1581e585eaeeecdd938621
ToppCell368C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TICRR PLCH1 RNF43 MYBL2

6.45e-05150644c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell368C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TICRR PLCH1 RNF43 MYBL2

6.45e-0515064478b8029e71d26f336a46274c8afef3435bf536b9
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

ZEB1 ANK3 NLRC5 MLLT3

6.62e-05151644999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellMild-Lymphoid-Plasma|Mild / Condition, Lineage, Cell class and cell subclass

TICRR IGHA1 LRP5 MYBL2

8.29e-051606447fdb849f5caf5a127a2582326215e11f8eb4fa0e
ToppCellMild-Lymphoid-Plasma-|Mild / Condition, Lineage, Cell class and cell subclass

TICRR IGHA1 LRP5 MYBL2

8.29e-05160644aa79848913910c01249d6cacf4ed53ec0e4f5c3d
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USF3 GPX3 LRP5 XRRA1

8.49e-051616443f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 AGAP5 SENP3 CUBN

8.49e-051616445fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

EFCAB6 ANK3 RAVER2 PLCH1

8.70e-0516264491cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IGHA1 GPX3 CUBN MYBL2

9.34e-051656447fe24be5bae7f0344243fb06cdfa02b4ddbb5a19
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR NCAPD3 LRR1 MYBL2

9.78e-05167644bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZEB1 ANK3 USP3 GOLGB1

9.78e-05167644ced6ed9b412739c6ced622523347c10295edbf53
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DACT1 PDE3A ANK3 LBX2

1.07e-04171644e59afa0a773dca3b9c208d17510ea55703b42598
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A RAVER2 PLCH1 MYO16

1.12e-041736442e35bf2b5534a289d93a09faae660f665c131062
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR NCAPD3 LRR1 MYBL2

1.12e-0417364420a20429aa898097d5ec4880ed64846558b5890f
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

ANK3 GPX3 CUBN RNF43

1.20e-0417664436f77d878a53b30465b0dea8333a3865dba75613
ToppCell15-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

ANK3 ACRBP LRRC2 AGAP2

1.31e-0418064499e2db9ad8e09fedc3542233553acece69f579f1
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLLT3 XRRA1 LRRC2 ALPK2

1.36e-04182644edfc598b7199ca1d8a399b264ab863c299b1eede
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-MPO+_mono-neutrophil|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TICRR ZHX1-C8orf76 NCF4 MYBL2

1.39e-0418364401c7f01498a9894920edf8243e41187cbdf90688
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A RAVER2 PLCH1 MYO16

1.42e-04184644658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DUOXA1 ANK3 MLLT3 B3GNT3

1.42e-04184644102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DACT1 PDE3A ZEB1 GPX3

1.45e-041856449f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A ZEB1 BACH1 WNK1

1.45e-04185644eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A CUBN ALK MYO16

1.51e-04187644d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 TTLL4 SENP3 RNF43

1.51e-04187644f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

PDE3A ANK3 LRRC2 ALPK2

1.57e-041896440a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BACH1 PLCH1 ALK MYO16

1.61e-041906448c9c230a509afaeee50644153974a5642b01a2b8
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

PDE3A ANK3 LRRC2 ALPK2

1.61e-04190644fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellsevere_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

DACT1 ANK3 IGHA1 MLLT3

1.64e-0419164455a282478488efd1561ea57a6f0218f55f711bb0
ToppCellStriatum-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-|Striatum / BrainAtlas - Mouse McCarroll V32

DUOXA1 NCF4 LBX2

1.66e-0474643e89506bd854a43b80f839ace36f7a3eaa8437215
ToppCellStriatum-Hematopoietic-MICROGLIA-MI2(C1qb)|Striatum / BrainAtlas - Mouse McCarroll V32

DUOXA1 NCF4 LBX2

1.66e-04746430dbce0b36eaf0c7a8b623478c85d1cac82c6693a
ToppCellStriatum-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)|Striatum / BrainAtlas - Mouse McCarroll V32

DUOXA1 NCF4 LBX2

1.66e-0474643093575ea862f3724d236817f04d98cc06b8addf0
ToppCellStriatum-Hematopoietic-MICROGLIA|Striatum / BrainAtlas - Mouse McCarroll V32

DUOXA1 NCF4 LBX2

1.66e-047464389effada90fbfef1844a905d3f82e9d16666eea5
ToppCellStriatum-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--|Striatum / BrainAtlas - Mouse McCarroll V32

DUOXA1 NCF4 LBX2

1.66e-0474643b14a950b90791a4cc5ffd29eb75a524abdd382da
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

DUOXA1 ANK3 MLLT3 PLCH1

1.67e-04192644efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TICRR NCAPD3 LRR1 MYBL2

1.71e-04193644cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A BACH1 ALK MYO16

1.74e-041946444f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

PDE3A ANK3 LRRC2 ALPK2

1.77e-04195644f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

PDE3A ANK3 LRRC2 ALPK2

1.77e-0419564475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellCOVID-19_Severe-CD4+_T_naive|World / disease group, cell group and cell class

DACT1 ANK3 IGHA1 MLLT3

1.81e-04196644b47c89eca6053c309fd328251c4fa33a76d16889
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ZHX1-C8orf76 NCAPD3 LRR1 CNTROB

1.81e-0419664436ed1918f70b6f5760bb088b15ce422998055cc7
ToppCellVE-cycling|VE / Condition, Cell_class and T cell subcluster

TICRR NCAPD3 LRR1 MYBL2

1.92e-0419964447c47ebc318a0b98841ca2656837bbd068899559
ToppCellVE-cycling-|VE / Condition, Cell_class and T cell subcluster

TICRR NCAPD3 LRR1 MYBL2

1.92e-04199644c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IGHA1 SLCO2B1 GPX3 GOLGB1

1.92e-04199644615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

LRP5 PLCH1 ALK MYO16

1.95e-042006444a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCellNeuronal-Inhibitory-iB-iB_1(GAD1)|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDE3A BACH1 PLCH1 ALK

1.95e-042006446c16151567ef100296f7c12cde350fc6ce146745
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

TICRR NCAPD3 CNTROB MYBL2

1.95e-042006449bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellNeuronal-Inhibitory-iB-iB_1(GAD1)-GLP1R|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDE3A BACH1 PLCH1 ALK

1.95e-042006447da0ccfcd024842ad85f34b523ead6ec61f7e864
ToppCellNeuronal-Inhibitory-iB-iB_1(GAD1)-GLP1R-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDE3A BACH1 PLCH1 ALK

1.95e-042006446b1c0176fe2ec6baedae44a7b330c2b32eea25cb
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDE3A CUBN ALK MYO16

1.95e-042006448a8f9d9e5ffab3f736c4bd0a5bb616d442d137d1
ToppCellSigmoid-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

NCAPD3 SLCO2B1 NCF4 MYBL2

1.95e-04200644372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCellNeuronal-Inhibitory-iB-iB_1(GAD1)-GLP1R--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDE3A BACH1 PLCH1 ALK

1.95e-04200644cdc43730334f8f623d936469acbae00a67c13a7b
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1|Neuronal / cells hierarchy compared to all cells using T-Statistic

LRP5 PLCH1 ALK MYO16

1.95e-04200644fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

LRP5 PLCH1 ALK MYO16

1.95e-04200644c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DUOXA1 ANK3 PITX1 GOLGB1

1.95e-04200644ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCelldistal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TICRR NCAPD3 LRR1 MYBL2

1.95e-042006441b65c97e8123d0572d31525d6a10bc7f16857959
Diseaseplasma beta-amyloid 1-42 measurement

ANK3 LRRC2

3.34e-0413622EFO_0005660
Diseaseurticaria

IGHA1 LRRC2

8.05e-0420622EFO_0005531
Diseasetriacylglycerol 56:5 measurement

MAGEC1 ALK

1.37e-0326622EFO_0010432
Diseasecardiovascular age measurement

AGAP5 ZC3H3

1.70e-0329622EFO_0803380
DiseaseMalignant neoplasm of breast

ZEB1 SLCO2B1 NLRC5 CUBN WNK1 ALK GOLGB1 AGAP2

1.78e-031074628C0006142
Diseasebipolar I disorder

ANK3 CUBN MYO16

3.29e-03141623EFO_0009963
Diseasestroke

PDE3A BTBD7 RNF43

3.49e-03144623EFO_0000712

Protein segments in the cluster

PeptideGeneStartEntry
LPAPKSSTDSASSCF

LINC01547

171

P58512
CPLSFLISEKDKSTP

BACH1

646

O14867
KAELISPTSPLSSCL

ALPK2

1531

Q86TB3
LFKSFSSAPPLILTC

MLLT3

306

P42568
SSAPPLILTCSADKK

MLLT3

311

P42568
CDTSHKTPFVSPLLA

ACRBP

396

Q8NEB7
FLKNSCPPTSELLGT

GPX3

151

P22352
PASPSFTLLSKLECS

ARGFX

31

A6NJG6
LAACKSLPSSPSHSA

AGAP2

576

Q99490
SFLDTSKDCSPSSPL

DMXL1

1896

Q9Y485
LPSVCLSSPASKTTL

RAVER2

591

Q9HCJ3
LNLSPTSSPLSSKSC

KANSL1L

491

A0AUZ9
ICSSSTSLSLPQSFP

MAGEC1

746

O60732
PPVDICLSKAISSSL

LRR1

86

Q96L50
SSGKLCSSLPPHLFS

MYO16

461

Q9Y6X6
PLKSSICSSTLLPST

KIAA2026

1396

Q5HYC2
CSPPTTFLLFSQKSA

LRP5

941

O75197
LSCPSQPFTSKLALL

EDEM2

556

Q9BV94
FSPSFKPKSILCSDS

KIAA0232

1066

Q92628
DLPPVLALSCSDTFT

OR5A2

181

Q8NGI9
LAKISPLSSPCSSPL

PDE3A

516

Q14432
LILSLPETFSSCLPF

CSNKA2IP

521

A0A1B0GTH6
DNSLSLKTPPECLLT

NPIPB8

276

E9PQR5
DSKSSALACTLPTLP

NCF4

76

Q15080
VELPTALCDSSTPLK

LRRC2

296

Q9BYS8
SCKLPSLSPVARSFS

KRT35

36

Q92764
PTSPLCALEELTSKT

LBX2

41

Q6XYB7
DTPPLLKLSCSDTHF

OR5AP2

186

Q8NGF4
SPKSPFLLANTLSLC

NLRC5

1176

Q86WI3
PILSKFCGTSLPSSQ

CUBN

2291

O60494
TDCLTLLHTPSKDSP

ASPHD2

11

Q6ICH7
PLEATLSLSDGCPKS

DACT1

196

Q9NYF0
KTSPCTDAKTPFLLA

EFCAB6

476

Q5THR3
ASPTSPKVFPLSLCS

IGHA1

1

P01876
FLAPSALKLSTPSSL

ANK3

1881

Q12955
TLLLFSLLVSPPTCK

B3GNT3

21

Q9Y2A9
AARCPFFKTLLSSSP

BTBD7

161

Q9P203
TPELPKDFHSLSTLC

KLF11

91

O14901
FLKNSCPPTSDLLGS

GPX6

151

P59796
LLFFSMATSLTSPCP

DUOXA1

221

Q1HG43
SKPITLPLDACSLSE

METTL4

186

Q8N3J2
LLPPKSSFLLSDISC

METTL4

256

Q8N3J2
APPVLCSSSSDLSLL

CNTROB

626

Q8N137
SPPLFKLSCSDTILK

OR5F1

181

O95221
SIFCPATSSLFEAKP

PCARE

1121

A6NGG8
AKSLAPAPLSTKSFT

PITX1

186

P78337
PFSCKRALLTSTIPL

SERTAD4-AS1

116

Q5TG53
SFLDSCNSLTPKSTP

MYBL2

431

P10244
PVDASSICPSTSSLF

RNF43

626

Q68DV7
FELDCTGPSIKSPSS

SHOC1

486

Q5VXU9
SATFPAPIKSSPCEL

ALK

536

Q9UM73
CFSPSISSTTSPKLN

AGAP5

376

A6NIR3
LPFTLNSGSPEKTCS

NCAPD3

1376

P42695
KSPLDPDSGLLSCTL

SENP3

231

Q9H4L4
LCKLPSFISLQSSPS

ZC3H3

906

Q8IXZ2
LFTSPLCDVSKKSPF

TICRR

1311

Q7Z2Z1
FKASLCLPTTSAPAS

SLCO2B1

156

O94956
VTSVLPPASLCKLSS

PTTG1IP

71

P53801
PSSLALSDAAKPCAS

USF3

926

Q68DE3
LPSPCKSKSLGDLTS

PLCH1

1486

Q4KWH8
LKTSQCSSPSLSASP

ZEB1

306

P37275
LSSSVCIAPDSAKFP

USP3

6

Q9Y6I4
KLLTSTTSTCLPPTN

WNK1

1701

Q9H4A3
LESFCLRSSPSEKSP

TTLL4

131

Q14679
FSTSETTKICSLPPI

XRRA1

336

Q6P2D8
LLCFPETLPESSLFS

ZHX1-C8orf76

181

Q96EF9
SCSSTPGLEEPLFKA

GOLGB1

1256

Q14789
ALPESSTCSSTLFLP

HECTD3

816

Q5T447