Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	poly(A) RNA polymerase activity	TENT5A TENT5C TENT5B	1.54e-04	12	182	3	GO:1990817
GeneOntologyMolecularFunction	5-methylcytosine dioxygenase activity	TET2 TET1	2.46e-04	3	182	2	GO:0070579
GeneOntologyMolecularFunction	sphingolipid binding	TRAF2 CLIP3 TNR PLTP	2.50e-04	34	182	4	GO:0046625
GeneOntologyBiologicalProcess	inner ear development	ATP6V1B1 HLA-C TTC39C TRIOBP ATP8B1 DICER1 MKS1 PTK7 HEY2 NTN1 ATP2B2	1.45e-05	253	180	11	GO:0048839
GeneOntologyCellularComponent	VCP-NPL4-UFD1 AAA ATPase complex	FAF1 FAF2 UBXN7	3.41e-05	8	180	3	GO:0034098
GeneOntologyCellularComponent	side of membrane	ROBO4 TRAF2 HLA-C BTNL8 PECAM1 L1CAM CR2 C2CD2L SIGLEC7 ASGR2 DNAI2 ULBP2 CD302 PLAUR GNB4 RAET1L GNB1 GNB2 GNB3	2.05e-04	875	180	19	GO:0098552
GeneOntologyCellularComponent	heterotrimeric G-protein complex	GNB4 GNB1 GNB2 GNB3	2.26e-04	35	180	4	GO:0005834
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	EMILIN2 PLAUR TNR	3.91e-04	17	180	3	GO:0098637
GeneOntologyCellularComponent	GTPase complex	GNB4 GNB1 GNB2 GNB3	4.20e-04	41	180	4	GO:1905360
GeneOntologyCellularComponent	external side of plasma membrane	ROBO4 HLA-C BTNL8 PECAM1 L1CAM CR2 SIGLEC7 ASGR2 DNAI2 ULBP2 CD302 PLAUR RAET1L	5.82e-04	519	180	13	GO:0009897
MousePheno	abnormal fear/anxiety-related behavior	CACNA1C WFS1 CEP85L TENT5A L1CAM ZDHHC7 ZNF804A FAF1 BRAP NEDD4 SYNGAP1 FBN2 PTPRG SSU72 ASPA EHMT1 PLAT PLAUR GNB4 ADPRHL1 GNB1 GNB2 ATP2B3 ANKS1A	3.05e-05	919	147	24	MP:0002065
MousePheno	abnormal floor plate morphology	CCP110 MKS1 PTK7 C2CD3 DISP1	5.88e-05	40	147	5	MP:0000925
MousePheno	abnormal outer hair cell stereociliary bundle morphology	WFS1 TRIOBP ATP8B1 MKS1 PTK7 ATP2B2	7.81e-05	68	147	6	MP:0004527
MousePheno	decreased anxiety-related response	CEP85L ZDHHC7 ZNF804A NEDD4 SYNGAP1 FBN2 SSU72 ASPA EHMT1 PLAT GNB4 GNB1 GNB2 ATP2B3 ANKS1A	8.31e-05	452	147	15	MP:0001364
MousePheno	abnormal nail morphology	L1CAM ITGB4 MKS1 FBN2 DSG4	8.38e-05	43	147	5	MP:0000579
MousePheno	abnormal anxiety-related response	CACNA1C WFS1 CEP85L TENT5A L1CAM ZDHHC7 ZNF804A NEDD4 SYNGAP1 FBN2 SSU72 ASPA EHMT1 PLAT PLAUR GNB4 GNB1 GNB2 ATP2B3 ANKS1A	9.47e-05	740	147	20	MP:0001362
Domain	Guanine_nucleotide-bd_bsu	GNB4 GNB1 GNB2 GNB3	4.05e-08	5	179	4	IPR016346
Domain	UAS	FAF1 FAF2 UBXN7	8.66e-07	3	179	3	SM00594
Domain	UAS	FAF1 FAF2 UBXN7	8.66e-07	3	179	3	IPR006577
Domain	Gprotein_B	GNB4 GNB1 GNB2 GNB3	1.64e-06	10	179	4	IPR001632
Domain	DUF1693	TENT5A TENT5C TENT5B	3.44e-06	4	179	3	IPR012937
Domain	DUF1693	TENT5A TENT5C TENT5B	3.44e-06	4	179	3	SM01153
Domain	NTP_transf_7	TENT5A TENT5C TENT5B	3.44e-06	4	179	3	PF07984
Domain	Tet_JBP	TET2 TET1	9.13e-05	2	179	2	PF12851
Domain	2OGFeDO_noxygenase_dom	TET2 TET1	9.13e-05	2	179	2	IPR024779
Domain	Tet_JBP	TET2 TET1	9.13e-05	2	179	2	SM01333
Domain	UBX_dom	FAF1 FAF2 UBXN7	2.31e-04	13	179	3	IPR001012
Domain	UBX	FAF1 FAF2 UBXN7	2.31e-04	13	179	3	PF00789
Domain	UBX	FAF1 FAF2 UBXN7	2.31e-04	13	179	3	PS50033
Domain	-	PPP4R1 MROH5 RIPOR3 RIF1 IPO9 ARVCF IPO13 CTNNB1 HECTD1	2.98e-04	222	179	9	1.25.10.10
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3	5.41e-04	4	179	2	IPR022141
Domain	FOXP-CC	FOXP2 FOXP1	5.41e-04	4	179	2	PF16159
Domain	FOXP-CC	FOXP2 FOXP1	5.41e-04	4	179	2	IPR032354
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3	5.41e-04	4	179	2	PF12424
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B3	5.41e-04	4	179	2	IPR006408
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3 PIK3R5	2.28e-06	24	130	5	M47460
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2 GNB3 PIK3R5	2.83e-06	25	130	5	M14301
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2 GNB3 PIK3R5	3.48e-06	26	130	5	MM15017
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3 PIK3R5	3.48e-06	26	130	5	M47456
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	CACNA1C GNB4 GNB1 GNB2 GNB3	5.12e-06	28	130	5	M10679
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3 PIK3R5	6.14e-06	29	130	5	M47466
Pathway	REACTOME_PLATELET_HOMEOSTASIS	PECAM1 GNB4 GNB1 GNB2 GNB3 ATP2B2 ATP2B3	6.21e-06	76	130	7	MM15051
Pathway	KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3 PIK3R5	8.65e-06	31	130	5	M47455
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2 GNB3 PIK3R5	1.02e-05	32	130	5	M14309
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3 PIK3R5	1.02e-05	32	130	5	M47962
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2 GNB3 PIK3R5	1.19e-05	33	130	5	MM15027
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	ADCY4 GNB4 GNB1 GNB2 GNB3	1.19e-05	33	130	5	MM15058
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	ADCY4 GNB4 GNB1 GNB2 GNB3	1.19e-05	33	130	5	M11575
Pathway	REACTOME_PLATELET_HOMEOSTASIS	PECAM1 GNB4 GNB1 GNB2 GNB3 ATP2B2 ATP2B3	1.42e-05	86	130	7	M916
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2 GNB3	2.40e-05	19	130	4	MM15021
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2 GNB3	2.40e-05	19	130	4	M926
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2 GNB3	2.98e-05	20	130	4	MM15572
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2 GNB3	2.98e-05	20	130	4	M27853
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2 GNB3	3.66e-05	21	130	4	M27409
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2 GNB3	3.66e-05	21	130	4	MM15159
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2 GNB3	4.44e-05	22	130	4	MM15016
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2 GNB3	4.44e-05	22	130	4	M841
Pathway	REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	ADCY4 GNB4 GNB1 GNB2 GNB3	4.49e-05	43	130	5	M29837
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	ADCY4 GNB4 GNB1 GNB2 GNB3	4.49e-05	43	130	5	M933
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	ADCY4 GNB4 GNB1 GNB2 GNB3	4.49e-05	43	130	5	M954
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	ADCY4 GNB4 GNB1 GNB2 GNB3	5.02e-05	44	130	5	MM15709
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2 GNB3	5.34e-05	23	130	4	MM15033
Pathway	KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	5.34e-05	23	130	4	M47549
Pathway	REACTOME_CA2_PATHWAY	GNB4 CTNNB1 GNB1 GNB2 GNB3	5.61e-05	45	130	5	MM15040
Pathway	REACTOME_GPER1_SIGNALING	ADCY4 GNB4 GNB1 GNB2 GNB3	5.61e-05	45	130	5	M45008
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2 GNB3	6.36e-05	24	130	4	M13115
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2 GNB3	6.36e-05	24	130	4	MM15088
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2 GNB3	6.36e-05	24	130	4	M18308
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2 GNB3	6.36e-05	24	130	4	MM14794
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2 GNB3	7.52e-05	25	130	4	MM15056
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2 GNB3	7.52e-05	25	130	4	M811
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	ADCY4 GNB4 GNB1 GNB2 GNB3	7.69e-05	48	130	5	M10775
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	CACNA1C ADCY4 GNB4 GNB1 GNB2 GNB3 ATP2B2 ATP2B3	7.76e-05	151	130	8	M39329
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	8.82e-05	26	130	4	M47561
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	8.82e-05	26	130	4	M47562
Pathway	KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	8.82e-05	26	130	4	M47557
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.03e-04	27	130	4	M47454
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2 GNB3	1.03e-04	27	130	4	MM15664
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	ADCY4 GNB4 GNB1 GNB2 GNB3	1.13e-04	52	130	5	M920
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1 GNB2 GNB3	1.57e-04	30	130	4	M18193
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	GNB4 GNB1 GNB2 GNB3	1.57e-04	30	130	4	MM14542
Pathway	BIOCARTA_CELL2CELL_PATHWAY	PECAM1 CTNNA3 CTNNB1	1.59e-04	12	130	3	M12851
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2 GNB3	1.79e-04	31	130	4	MM15094
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.79e-04	31	130	4	M47554
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.79e-04	31	130	4	M47459
Pathway	KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.79e-04	31	130	4	M47540
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.79e-04	31	130	4	M47541
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1 GNB2 GNB3	2.03e-04	32	130	4	M861
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1 GNB2 GNB3	2.03e-04	32	130	4	MM15148
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1 GNB2 GNB3	2.03e-04	32	130	4	MM15143
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB4 GNB1 GNB2 GNB3	2.03e-04	32	130	4	MM14983
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	ADCY4 GNB4 GNB1 GNB2 GNB3	2.25e-04	60	130	5	MM15708
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	ADCY4 GNB4 GNB1 GNB2 GNB3	2.25e-04	60	130	5	M976
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2 GNB3	2.30e-04	33	130	4	MM15020
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	2.30e-04	33	130	4	M47550
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1 GNB2 GNB3	2.30e-04	33	130	4	MM15066
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1 GNB2 GNB3	2.30e-04	33	130	4	M10322
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2 GNB3	2.30e-04	33	130	4	M9379
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	CACNA1C GNB4 GNB1 GNB2 GNB3	2.43e-04	61	130	5	MM15071
Pathway	WP_ONECARBON_METABOLISM	GART AHCYL2 EHMT2 EHMT1	2.58e-04	34	130	4	MM15859
Pathway	REACTOME_CA2_PATHWAY	GNB4 CTNNB1 GNB1 GNB2 GNB3	2.62e-04	62	130	5	M27321
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2 GNB3	2.90e-04	35	130	4	M1075
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2 GNB3	3.24e-04	36	130	4	MM14544
Pathway	REACTOME_COOPERATION_OF_PDCL_PHLP1_AND_TRIC_CCT_IN_G_PROTEIN_BETA_FOLDING	GNB4 GNB1 GNB2 GNB3	4.00e-04	38	130	4	M27656
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	CACNA1C ADCY4 GNB4 GNB1 GNB3 ATP2B2 ATP2B3	4.22e-04	147	130	7	MM15854
Pathway	REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING	GNB4 GNB1 GNB2 GNB3	4.42e-04	39	130	4	MM15003
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	CACNA1C ADCY4 GNB4 GNB1 GNB2 GNB3	4.86e-04	108	130	6	M17034
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2 GNB3	4.88e-04	40	130	4	MM15115
Pathway	REACTOME_OPIOID_SIGNALLING	ADCY4 GNB4 GNB1 GNB2 GNB3	4.94e-04	71	130	5	MM14491
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	ZDHHC7 GNB4 GNB1 GNB2 GNB3	4.94e-04	71	130	5	MM15590
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	CACNA1C GNB4 GNB1 GNB2 GNB3	5.27e-04	72	130	5	MM14631
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB4 GNB1 GNB2 GNB3	5.89e-04	42	130	4	M791
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	CACNA1C ITGB4 CTNNA3 CACNG4 CTNNB1	5.98e-04	74	130	5	M16376
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	CACNA1C ITGB4 CTNNA3 CACNG4 CTNNB1	5.98e-04	74	130	5	M39462
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	ZDHHC7 GNB4 GNB1 GNB2 GNB3	6.36e-04	75	130	5	M27874
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	CACNA1C GNB4 GNB1 GNB2 GNB3	7.61e-04	78	130	5	M1921
Pathway	WP_HISTONE_MODIFICATIONS	EHMT2 EHMT1	8.29e-04	5	130	2	MM15874
Pathway	REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1	CTNNB1 GNB1 GNB3	9.03e-04	21	130	3	M932
Pathway	REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION	CTNNB1 GNB1 GNB3	1.35e-03	24	130	3	M928
Pathway	REACTOME_OPIOID_SIGNALLING	ADCY4 GNB4 GNB1 GNB2 GNB3	1.45e-03	90	130	5	M6467
Pathway	WP_CORTICOTROPINRELEASING_HORMONE_SIGNALING	TBX19 CTNNB1 GNB1 GNB2 GNB3	1.60e-03	92	130	5	M39441
Pathway	REACTOME_CARDIOGENESIS	LDB1 HEY2 CTNNB1	1.91e-03	27	130	3	M48011
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNG1 GNB4 GNB1 GNB2 GNB3	2.11e-03	98	130	5	MM14545
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	ADCY4 GNB4 CACNG4 GNB1 GNB2 GNB3	2.16e-03	144	130	6	MM14501
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	GNB4 GNB1 GNB2 GNB3	2.26e-03	60	130	4	MM14964
Pathway	WP_CYTOSINE_METHYLATION	TET2 TET1	2.28e-03	8	130	2	M39348
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	CACNA1C CACNG4	2.28e-03	8	130	2	MM15197
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNG1 GNB4 GNB1 GNB2 GNB3	2.63e-03	103	130	5	M1073
Pathway	BIOCARTA_CELL2CELL_PATHWAY	PECAM1 CTNNB1	2.91e-03	9	130	2	MM1366
Pathway	WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS	ADCY4 GNB4 GNB1 GNB2 GNB3 CNN1	3.22e-03	156	130	6	M39475
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	ADCY4 GLUL GNB4 CACNG4 GNB1 GNB2 GNB3	3.41e-03	211	130	7	MM14502
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB4 GNB1 GNB2 GNB3	7.42e-10	4	183	4	1543505
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB4 GNB1 GNB2 GNB3	7.42e-10	4	183	4	12512701
Pubmed	Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.	GNB4 CTNNB1 GNB1 GNB2 GNB3	2.93e-09	12	183	5	20186915
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB4 GNB1 GNB2 GNB3	1.10e-08	6	183	4	16884933
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA3 ILF2 FOXP2 SYNE1 UBR4 TRIOBP MPRIP NEDD4 SYNGAP1 UBE2O LDB1 ARVCF EHMT2 GLUL EHMT1 CTNNB1 GNB1 GNB2 TNR GOLGA2 ANKS1A	4.39e-08	963	183	21	28671696
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GNB4 GNB1 GNB2 GNB3	5.11e-08	8	183	4	2328987
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PPP4R1 TET2 TRAF2 CEP85L SYNE1 UBR4 TRIOBP NCKAP5 WDR59 FAF1 MPRIP SYNGAP1 UBE2O LDB1 EHMT2 ASPA GLUL ENPP5 PLAUR ZNF565 GNB1 USPL1 HECTD1 MPPED2	8.18e-08	1285	183	24	35914814
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	CASP8AP2 TRAF2 ILF2 FOXP2 HLA-C COPE AOAH PGLYRP3 CR2 FAF1 UBE2O SIGLEC7 ASGR2 ULBP2 FOXP1 CD302 PLAUR RAET1L MX2	8.52e-08	824	183	19	20237496
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB4 GNB1 GNB2 GNB3	9.16e-08	9	183	4	10339615
Pubmed	Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes.	GNB1 GNB2 GNB3	1.43e-07	3	183	3	11913780
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB4 GNB1 GNB2 GNB3	1.52e-07	10	183	4	9733924
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB4 GNB1 GNB2 GNB3	1.52e-07	10	183	4	28334111
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	GNB4 GNB1 GNB2 GNB3	2.38e-07	11	183	4	25982117
Pubmed	The G protein subunit gene families.	GNB4 GNB1 GNB2 GNB3	2.38e-07	11	183	4	10644457
Pubmed	Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families.	GNB4 GNB1 GNB2 GNB3	3.55e-07	12	183	4	8636150
Pubmed	Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.	GNB4 GNB1 GNB2 GNB3	3.55e-07	12	183	4	16301321
Pubmed	The cationic region of Rhes mediates its interactions with specific Gbeta subunits.	GNB1 GNB2 GNB3	5.71e-07	4	183	3	19255495
Pubmed	Glucagon and regulation of glucose metabolism.	ADCY4 GNB4 GNB1 GNB2 GNB3	5.81e-07	31	183	5	12626323
Pubmed	Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.	GNB4 GNB1 GNB2 GNB3	9.68e-07	15	183	4	12486123
Pubmed	Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli.	ROBO4 PECAM1 HEY2 CTNNB1	9.68e-07	15	183	4	19087347
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	SYNE1 MPRIP SYNGAP1 UBE2O ARVCF GLUL CTNNB1 GNB1 GNB2 ANKS1A	9.72e-07	251	183	10	27507650
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	PPP4R1 TET2 L1CAM DICER1 FAF1 NEDD4 RIF1 PTPRG TET1 FOXP1 NTN1 CEP152 CTNNB1 HECTD1	1.09e-06	536	183	14	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	PPP4R1 TET2 L1CAM DICER1 FAF1 NEDD4 RIF1 PTPRG TET1 FOXP1 NTN1 CEP152 CTNNB1 HECTD1	1.14e-06	538	183	14	10512203
Pubmed	iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging.	FOXP2 PECAM1 NTN1 CTNNB1	1.28e-06	16	183	4	25417164
Pubmed	Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.	GNB4 GNB1 GNB2 GNB3	1.67e-06	17	183	4	19376773
Pubmed	Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.	GNB4 GNB1 GNB2	2.83e-06	6	183	3	16371464
Pubmed	Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells.	DICER1 EHMT2 EHMT1	2.83e-06	6	183	3	23284137
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 FLI1 NCOA3 FOXP2 LDB1 EHMT2 TET1 EHMT1 FOXP1 CTNNB1 GNB2	2.87e-06	351	183	11	38297188
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	NCOA3 MPRIP GNB4 GNB1 GNB2	3.13e-06	43	183	5	26487511
Pubmed	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.	GNB4 GNB1 GNB3	4.94e-06	7	183	3	10570481
Pubmed	Endothelial Unc5B controls blood-brain barrier integrity.	ROBO4 NTN1 CTNNB1	4.94e-06	7	183	3	35246514
Pubmed	Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing.	RIF1 EHMT2 EHMT1	4.94e-06	7	183	3	24735877
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ILF2 HLA-C C6orf89 WFS1 L1CAM DCLRE1B GOSR2 PTK7 SYNGAP1 ZNF16 RIF1 FBN2 IPO9 FAF2 DHRS7 CTNNB1 ZNF664 PRAME ZNF239 AMIGO2	6.12e-06	1203	183	20	29180619
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TRAF7 UBR4 FBXL14 L1CAM ZDHHC7 ITGB4 WDR59 MPRIP C2CD2L C2CD3 ZBED4 ARVCF KCNG1 SSU72 EHMT1 TNK2 HECTD1 SCARA3 ZNF614	6.60e-06	1105	183	19	35748872
Pubmed	Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.	UBR4 BRAP UBE2O FAF2 HECTD1	6.68e-06	50	183	5	17550899
Pubmed	Gβγ interacts with mTOR and promotes its activation.	GNB1 GNB2 GNB3	7.87e-06	8	183	3	24462769
Pubmed	A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.	GNB1 GNB2 GNB3	7.87e-06	8	183	3	9789084
Pubmed	Apoptosis regulates endothelial cell number and capillary vessel diameter but not vessel regression during retinal angiogenesis.	FLI1 PECAM1 CTNNB1 GOLGA2	8.61e-06	25	183	4	27471260
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	TRAF2 UBR4 BRAP NEDD4 HERC3 HECTD1	1.15e-05	95	183	6	29643511
Pubmed	Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation.	FOXP2 BRAP FOXP1 CTNNB1	1.18e-05	27	183	4	28768199
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNB4 GNB1 GNB2 GNB3	1.38e-05	28	183	4	8858601
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	TRAF2 HLA-C WDR59 FAF1 FAF2 UBXN7 ATP2B2 ATP2B3	1.62e-05	209	183	8	26389662
Pubmed	Functional proteomics mapping of a human signaling pathway.	FLI1 TENT5A PECAM1 UBR4 E4F1 FAF1 EPG5 NEDD4 FBN2 LDB1 GLUL CTNNB1 KNL1	1.67e-05	591	183	13	15231748
Pubmed	Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes.	FOXP2 L1CAM FOXP1	1.67e-05	10	183	3	26245956
Pubmed	Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α2a-adrenergic receptors.	GNB4 GNB1 GNB2	2.29e-05	11	183	3	34932372
Pubmed	Cell Surface Downregulation of NK Cell Ligands by Patient-Derived HIV-1 Vpu and Nef Alleles.	HLA-C ULBP2 RAET1L	2.29e-05	11	183	3	26656785
Pubmed	Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.	CCP110 FOXP2 MKS1 CTNNB1	2.69e-05	33	183	4	30626697
Pubmed	Identification of human protein interaction domains using an ORFeome-based yeast two-hybrid fragment library.	KLHL32 EHMT2 CTNNA3 CTNNB1	2.69e-05	33	183	4	23718855
Pubmed	Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5-Methylcytosine Bases.	TET2 TET1	2.75e-05	2	183	2	27362828
Pubmed	Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.	TET2 TET1	2.75e-05	2	183	2	23415914
Pubmed	Molecular characterization of DICER1-mutated pituitary blastoma.	DICER1 PRAME	2.75e-05	2	183	2	33644822
Pubmed	PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus.	PECAM1 CTNNB1	2.75e-05	2	183	2	37580771
Pubmed	Early Expression of Tet1 and Tet2 in Mouse Zygotes Altered DNA Methylation Status and Affected Embryonic Development.	TET2 TET1	2.75e-05	2	183	2	35955629
Pubmed	Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.	TET2 TET1	2.75e-05	2	183	2	24474761
Pubmed	β-catenin regulates FOXP2 transcriptional activity via multiple binding sites.	FOXP2 CTNNB1	2.75e-05	2	183	2	33284517
Pubmed	Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis.	CACNA1C ZNF804A	2.75e-05	2	183	2	35786202
Pubmed	ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm.	ROBO4 PECAM1	2.75e-05	2	183	2	30455415
Pubmed	The histone H3 lysine 9 methyltransferase G9a/GLP complex activity is required for long-term consolidation of spatial memory in mice.	EHMT2 EHMT1	2.75e-05	2	183	2	33609736
Pubmed	Investigating protein-protein interactions in live cells using bioluminescence resonance energy transfer.	FOXP2 FOXP1	2.75e-05	2	183	2	24893771
Pubmed	Heterodimerization of H3K9 histone methyltransferases G9a and GLP activates methyl reading and writing capabilities.	EHMT2 EHMT1	2.75e-05	2	183	2	34619147
Pubmed	FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.	FOXP2 FOXP1	2.75e-05	2	183	2	27224915
Pubmed	Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors.	FOXP2 FOXP1	2.75e-05	2	183	2	11358962
Pubmed	Equivalent missense variant in the FOXP2 and FOXP1 transcription factors causes distinct neurodevelopmental disorders.	FOXP2 FOXP1	2.75e-05	2	183	2	28741757
Pubmed	SPATA33 affects the formation of cell adhesion complex by interacting with CTNNA3 in TM4 cells.	SPATA33 CTNNA3	2.75e-05	2	183	2	35536443
Pubmed	Dicer is required for proper liver zonation.	DICER1 CTNNB1	2.75e-05	2	183	2	19718708
Pubmed	Evidence of a sex-dependent restrictive epigenome in schizophrenia.	EHMT2 EHMT1	2.75e-05	2	183	2	25935252
Pubmed	FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells.	TENT5C TENT5B	2.75e-05	2	183	2	32009146
Pubmed	Associations of schizophrenia risk genes ZNF804A and CACNA1C with schizotypy and modulation of attention in healthy subjects.	CACNA1C ZNF804A	2.75e-05	2	183	2	31076262
Pubmed	Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells.	EHMT2 EHMT1	2.75e-05	2	183	2	19531572
Pubmed	G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription.	EHMT2 EHMT1	2.75e-05	2	183	2	18818694
Pubmed	Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia.	PTPRG CTNNB1	2.75e-05	2	183	2	32225105
Pubmed	Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome.	EHMT2 EHMT1	2.75e-05	2	183	2	29554304
Pubmed	Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism.	TET2 TET1	2.75e-05	2	183	2	24214992
Pubmed	A role for the plasminogen activator system in inflammation and neurodegeneration in the central nervous system during experimental allergic encephalomyelitis.	PLAT PLAUR	2.75e-05	2	183	2	16049338
Pubmed	Ten-eleven translocation protein 1 modulates medulloblastoma progression.	TET2 TET1	2.75e-05	2	183	2	33926529
Pubmed	Coordination of engineered factors with TET1/2 promotes early-stage epigenetic modification during somatic cell reprogramming.	TET2 TET1	2.75e-05	2	183	2	24672749
Pubmed	Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation.	TET2 TET1	2.75e-05	2	183	2	26598602
Pubmed	Unsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of β-Catenin.	FAF1 CTNNB1	2.75e-05	2	183	2	26456834
Pubmed	Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.	TET2 TET1	2.75e-05	2	183	2	26586431
Pubmed	Context-Dependent Requirement of Euchromatic Histone Methyltransferase Activity during Reprogramming to Pluripotency.	EHMT2 EHMT1	2.75e-05	2	183	2	32976761
Pubmed	PTK7: a cell polarity receptor with multiple facets.	PTK7 CTNNB1	2.75e-05	2	183	2	21415598
Pubmed	Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns.	TET2 TET1	2.75e-05	2	183	2	35075236
Pubmed	Ten-Eleven Translocation 1 and 2 Confer Overlapping Transcriptional Programs for the Proliferation of Cultured Adult Neural Stem Cells.	TET2 TET1	2.75e-05	2	183	2	27778125
Pubmed	Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels.	CACNA1C NEDD4	2.75e-05	2	183	2	21220429
Pubmed	EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.	EHMT2 EHMT1	2.75e-05	2	183	2	26320100
Pubmed	EHMT1/EHMT2 in EMT, cancer stemness and drug resistance: emerging evidence and mechanisms.	EHMT2 EHMT1	2.75e-05	2	183	2	34954891
Pubmed	Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.	TENT5A TENT5C	2.75e-05	2	183	2	33882302
Pubmed	Association of CACNA1C and SYNE1 in offspring of patients with psychiatric disorders.	CACNA1C SYNE1	2.75e-05	2	183	2	27620326
Pubmed	A functional neuroimaging association study on the interplay between two schizophrenia genome-wide associated genes (CACNA1C and ZNF804A).	CACNA1C ZNF804A	2.75e-05	2	183	2	35796825
Pubmed	Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.	TET2 TET1	2.75e-05	2	183	2	28783731
Pubmed	GLP overexpression is associated with poor prognosis in Chronic Lymphocytic Leukemia and its inhibition induces leukemic cell death.	EHMT2 EHMT1	2.75e-05	2	183	2	29855824
Pubmed	Novel Epigenetic Controlling of Hypoxia Pathway Related to Overexpression and Promoter Hypomethylation of TET1 and TET2 in RPE Cells.	TET2 TET1	2.75e-05	2	183	2	28252217
Pubmed	Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor.	FLI1 PECAM1	2.75e-05	2	183	2	10891501
Pubmed	Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis.	PTPRG CTNNB1	2.75e-05	2	183	2	21112398
Pubmed	Identification and functional characterization of de novo FOXP1 variants provides novel insights into the etiology of neurodevelopmental disorder.	FOXP2 FOXP1	2.75e-05	2	183	2	26647308
Pubmed	FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma.	FOXP1 CTNNB1	2.75e-05	2	183	2	25650440
Pubmed	Differential and Overlapping Pattern of Foxp1 and Foxp2 Expression in the Striatum of Adult Mouse Brain.	FOXP2 FOXP1	2.75e-05	2	183	2	30031127
Pubmed	Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors.	TET2 TET1	2.75e-05	2	183	2	30045709
Pubmed	Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils.	GNB1 GNB2	2.75e-05	2	183	2	20525682
Pubmed	Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer.	EHMT2 EHMT1	2.75e-05	2	183	2	33283949
Interaction	GNGT2 interactions	GNB4 GNB1 GNB2 GNB3	3.01e-06	12	182	4	int:GNGT2
Interaction	CRX interactions	TET2 FLI1 NCOA3 FOXP2 KLHL32 LDB1 EHMT2 UBXN7 CTNNA3 EHMT1 IPO13 FOXP1	3.55e-06	254	182	12	int:CRX
Interaction	GNG11 interactions	GNB4 GNB1 GNB2 GNB3	1.40e-05	17	182	4	int:GNG11
Interaction	RGS6 interactions	GNB4 GNB1 GNB2 GNB3	1.78e-05	18	182	4	int:RGS6
Interaction	EGR2 interactions	TET2 FLI1 NCOA3 FOXP2 LDB1 TET1 FOXP1 CTNNB1 GOLGA2	2.60e-05	171	182	9	int:EGR2
Interaction	GNG7 interactions	GNB4 GNB1 GNB2 GNB3	2.78e-05	20	182	4	int:GNG7
Interaction	KCNB2 interactions	CACNA1C PTK7 SYNGAP1 RHOH KCNG1 AMIGO2	2.90e-05	66	182	6	int:KCNB2
Interaction	DLGAP1 interactions	SYNE1 MPRIP SYNGAP1 UBE2O ARVCF GLUL CTNNB1 GNB1 GNB2	3.89e-05	180	182	9	int:DLGAP1
GeneFamily	UBX domain containing	FAF1 FAF2 UBXN7	7.96e-05	13	121	3	364
GeneFamily	TNF receptor associated factors	TRAF7 TRAF2	9.13e-04	7	121	2	1056
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	MRC1 PECAM1 L1CAM CR2 ADAM8 ITGB4 SIGLEC7 CD302 PLAUR	1.34e-03	394	121	9	471
GeneFamily	ATPases Ca2+ transporting	ATP2B2 ATP2B3	1.55e-03	9	121	2	1209
GeneFamily	WD repeat domain containing	TRAF7 WDR59 DNAI2 GNB4 GNB1 GNB2 GNB3	1.92e-03	262	121	7	362
GeneFamily	X-linked mental retardation\|RNA helicases	DICER1 IFIH1	2.35e-03	11	121	2	1168
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1	CACNA1C MRC1 FLI1 ROBO4 FOXP2 HLA-C SYNE1 TTC39C EMILIN2 TENT5C ARL9 ARFGAP3 CPXM1 PCSK4 MPPED2 SCARA3 PIK3R5	1.08e-05	589	179	17	Facebase_RNAseq_e9.5_Maxillary Arch_2500_K1
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 FLI1 PECAM1 AOAH EMILIN2 ZNF804A SIGLEC7 GNB4 PIK3R5 PLTP	1.12e-08	199	184	10	6ce7612ee2ae211eb0f73391e96089ad5431c537
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLI1 ADCY4 PECAM1 ATP8B1 ITGB4 NEDD4 PTPRG FOXP1 PLAT PLTP	1.18e-08	200	184	10	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 CASP8AP2 ROBO4 BTNL8 SYNE1 PECAM1 PKHD1L1 PLAT ANKS1A	4.58e-08	173	184	9	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ROBO4 BTNL8 SYNE1 PECAM1 NEDD4 PTPRG PLAT TNR	4.58e-08	173	184	9	afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	FLI1 ADCY4 HLA-C PECAM1 ATP8B1 PKHD1L1 ITGB4 NEDD4 FOXP1	8.92e-08	187	184	9	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	Control-Myeloid-Transitioning_MDM\|Control / group, cell type (main and fine annotations)	TET2 MRC1 AOAH EMILIN2 MS4A7 GLUL PLAUR PIK3R5 PLTP	1.02e-07	190	184	9	d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 FLI1 THEMIS TTC39C AOAH TENT5C RHOH TNK2 PIK3R5	1.22e-07	194	184	9	4dfc890bacf133cfb6ec7c8b73f084f2491cf78e
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	FLI1 ADCY4 HLA-C PECAM1 ATP8B1 PKHD1L1 ITGB4 FOXP1 PLAT	1.22e-07	194	184	9	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	MRC1 AOAH EMILIN2 MS4A7 GLUL PLAUR MPPED2 PIK3R5 PLTP	1.28e-07	195	184	9	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLI1 ROBO4 NCOA3 BTNL8 SYNE1 PECAM1 NEDD4 PLAT HERC3	1.33e-07	196	184	9	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MRC1 ROBO4 ADCY4 WFS1 SYNE1 PECAM1 PKHD1L1 NTN1 ANKS1A	1.45e-07	198	184	9	99d6a64f3410dae3019161feef20a8f06081a24b
ToppCell	Immune\|World / Lineage, Cell type, age group and donor	MRC1 FLI1 AOAH EMILIN2 ZNF804A RHOH GLUL PLAUR PIK3R5	1.45e-07	198	184	9	65681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCell	Parenchymal-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 FLI1 PECAM1 AOAH EMILIN2 ZNF804A GLUL PLAUR PIK3R5	1.52e-07	199	184	9	7ee2805fd9143eba11bf6832267b62189683608b
ToppCell	COVID-19-kidney-Glomerular_EC\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C MRC1 FLI1 ROBO4 BTNL8 SYNE1 PECAM1 PKHD1L1 PLAT	1.52e-07	199	184	9	fffd2f9042b55531dac4e5b463b5cee80402e7bb
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF804A TNK2 NTN1 CACNG4 PLEKHH2 TNR MPPED2 UNC80 CCSER1	1.58e-07	200	184	9	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLI1 ROBO4 ADCY4 PECAM1 NCKAP5 NEDD4 PTPRG TNK2 FOXP1	1.58e-07	200	184	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF804A TNK2 NTN1 CACNG4 PLEKHH2 TNR MPPED2 UNC80 CCSER1	1.58e-07	200	184	9	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF804A TNK2 NTN1 CACNG4 PLEKHH2 TNR MPPED2 UNC80 CCSER1	1.58e-07	200	184	9	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF804A TNK2 NTN1 CACNG4 PLEKHH2 TNR MPPED2 UNC80 CCSER1	1.58e-07	200	184	9	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLI1 ROBO4 ADCY4 PECAM1 NCKAP5 PTPRG TNK2 FOXP1 CCSER1	1.58e-07	200	184	9	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF804A TNK2 NTN1 CACNG4 PLEKHH2 TNR MPPED2 UNC80 CCSER1	1.58e-07	200	184	9	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ZNF804A TNK2 NTN1 CACNG4 PLEKHH2 TNR MPPED2 UNC80 CCSER1	1.58e-07	200	184	9	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLI1 AOAH EMILIN2 ZNF804A SIGLEC7 ASGR2 PLAUR PIK3R5 MX2	1.58e-07	200	184	9	b4277b6faa69f20974696c7c422311f5c89e3663
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CASP8AP2 SGSM1 ADAMTSL3 STRIP2 ENPP5 ADPRHL1 SKA1 ZNF239	4.67e-07	166	184	8	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CASP8AP2 SGSM1 ADAMTSL3 STRIP2 ENPP5 ADPRHL1 SKA1 ZNF239	6.11e-07	172	184	8	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PECAM1 PKHD1L1 ITGB4 LRRC3B HEY2 PLAT ATP2B2 AMIGO2	7.92e-07	178	184	8	9f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF2 TENT5A PECAM1 EMILIN2 ATP8B1 NEDD4 GNB4 DISP1	7.92e-07	178	184	8	cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXP2 SYNE1 LRRC3B TET1 PLAT MPPED2 CNN1 AMIGO2	7.92e-07	178	184	8	0fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell	Control-Myeloid-Dendritic_cells\|Control / group, cell type (main and fine annotations)	MRC1 AOAH EMILIN2 MS4A7 GLUL PLAUR MPPED2 PIK3R5	8.62e-07	180	184	8	25ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PECAM1 ITGB4 HEY2 PLAT NTN1 PLAC9 ATP2B2 SCARA3	9.36e-07	182	184	8	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PECAM1 ITGB4 HEY2 PLAT NTN1 PLAC9 ATP2B2 SCARA3	9.36e-07	182	184	8	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 IKZF2 THEMIS TTC39C AOAH RHOH FOXP1 PIK3R5	1.10e-06	186	184	8	9d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 IKZF2 THEMIS TTC39C AOAH RHOH FOXP1 PIK3R5	1.10e-06	186	184	8	bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SGSM1 ITGB4 HEY2 PLAT NTN1 PLAC9 ATP2B2 SCARA3	1.10e-06	186	184	8	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 IKZF2 THEMIS TTC39C AOAH RHOH FOXP1 PIK3R5	1.10e-06	186	184	8	924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 PECAM1 ITGB4 LRRC3B HEY2 PLAT ATP2B2 AMIGO2	1.10e-06	186	184	8	5302399825f213d105ac70b91366a4513b732838
ToppCell	Control-Endothelial_cells-Endothelial_cells_(general)\|Control / group, cell type (main and fine annotations)	FLI1 ROBO4 ADCY4 BTNL8 PECAM1 PTPRG TNR ANKS1A	1.15e-06	187	184	8	fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	CACNA1C MYH7B TENT5A NCKAP5 FBN2 CTNNA3 CNN1 CCSER1	1.24e-06	189	184	8	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	FLI1 PECAM1 AOAH EMILIN2 MS4A7 GLUL PIK3R5 MX2	1.24e-06	189	184	8	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLI1 ADCY4 PECAM1 ATP8B1 PKHD1L1 ITGB4 PLAT GNB4	1.29e-06	190	184	8	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PKHD1L1 ITGB4 CLIP3 LRRC3B HEY2 PLAT PLAC9 SCARA3	1.29e-06	190	184	8	3cf464664d6aa22b212e60b70885953887e92483
ToppCell	droplet-Lung-nan-21m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 PECAM1 NCKAP5 ATP8B1 ITGB4 NTN1 PLTP AMIGO2	1.35e-06	191	184	8	92b2faa72c184b6ae49530fd3b50848510904997
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C SYNE1 ADAMTSL3 CLIP3 CTNNA3 HEY2 SCARA3 CNN1	1.35e-06	191	184	8	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	droplet-Lung-nan-21m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 PECAM1 NCKAP5 ATP8B1 ITGB4 NTN1 PLTP AMIGO2	1.35e-06	191	184	8	d0bbbf42d00165a53253c833adef65da6ec36bba
ToppCell	Control-Myeloid\|Control / group, cell type (main and fine annotations)	MRC1 PECAM1 AOAH EMILIN2 ZNF804A MS4A7 GLUL PIK3R5	1.35e-06	191	184	8	9c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 FLI1 THEMIS AOAH EMILIN2 ZNF804A RHOH PIK3R5	1.35e-06	191	184	8	468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	FLI1 ROBO4 NCOA3 ADCY4 HLA-C SYNE1 PECAM1 PKHD1L1	1.40e-06	192	184	8	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	MRC1 AOAH EMILIN2 MS4A7 GLUL MPPED2 PIK3R5 PLTP	1.45e-06	193	184	8	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLI1 ADCY4 PECAM1 ATP8B1 PKHD1L1 ITGB4 PTPRG PLAT	1.45e-06	193	184	8	9ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ROBO4 BTNL8 SYNE1 PECAM1 PKHD1L1 PLAT ANKS1A	1.45e-06	193	184	8	456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 THEMIS AOAH EMILIN2 ZNF804A RHOH PLAUR PIK3R5	1.51e-06	194	184	8	96f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCell	droplet-Lung-21m-Endothelial-venous_endothelial-vein_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY4 PECAM1 NCKAP5 ITGB4 FOXP1 NTN1 PLTP AMIGO2	1.51e-06	194	184	8	17d530982789acc5e6889b215f3d433d138a41c4
ToppCell	droplet-Lung-21m-Endothelial-venous_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY4 PECAM1 NCKAP5 ITGB4 FOXP1 NTN1 PLTP AMIGO2	1.51e-06	194	184	8	db7b0c77ad88f7b74d85679f1fb8ee7140ac3f62
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 FLI1 THEMIS AOAH EMILIN2 RHOH PIK3R5 PLTP	1.51e-06	194	184	8	0866ab6792cee274a71991d5c37a37f574ff446e
ToppCell	droplet-Lung-21m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADCY4 PECAM1 NCKAP5 ITGB4 FOXP1 NTN1 PLTP AMIGO2	1.51e-06	194	184	8	5992b9409d5855eff2afc3acd201ccd25420d2e0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ROBO4 BTNL8 SYNE1 PECAM1 PTPRG PLAT ANKS1A	1.57e-06	195	184	8	23ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ROBO4 ADCY4 SYNE1 PECAM1 NEDD4 PTPRG PLAT	1.63e-06	196	184	8	48b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ROBO4 ADCY4 SYNE1 PECAM1 NEDD4 PTPRG PLAT	1.63e-06	196	184	8	473980c827443464d08a0be28c53e3536369b12a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ROBO4 ADCY4 SYNE1 PECAM1 NEDD4 PTPRG PLAT	1.63e-06	196	184	8	8f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	MRC1 AOAH EMILIN2 ZNF804A GLUL PLAUR PIK3R5 PLTP	1.63e-06	196	184	8	a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MRC1 FLI1 THEMIS AOAH EMILIN2 RHOH PLAUR PIK3R5	1.70e-06	197	184	8	c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	MRC1 FLI1 AOAH EMILIN2 ZNF804A GLUL PLAUR PIK3R5	1.70e-06	197	184	8	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MRC1 ROBO4 ADCY4 WFS1 PECAM1 PKHD1L1 NTN1 ANKS1A	1.76e-06	198	184	8	5d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ROBO4 ADCY4 HLA-C PECAM1 RIPOR3 ULBP2 TNR DISP1	1.76e-06	198	184	8	40c2171e79f578c9116d872c189f953dc61d052d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ROBO4 NCOA3 BTNL8 SYNE1 PECAM1 PKHD1L1 PLAT ANKS1A	1.76e-06	198	184	8	92416e65a0dc1a4bf931833407620ea05d362f56
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLI1 ADCY4 PECAM1 PKHD1L1 ITGB4 PLAT NTN1 GNB4	1.83e-06	199	184	8	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	SYNE1 ADAMTSL3 MPRIP FBN2 CTNNA3 PLAT PLAC9 CNN1	1.90e-06	200	184	8	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	control-Neutrophil\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 UBR4 AOAH EMILIN2 GLUL CD302 PLAUR GNB1	1.90e-06	200	184	8	b5d197472799cc61d7497faed91ac2564ae4930a
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 PECAM1 EMILIN2 ZNF804A GLUL PLAUR PIK3R5 AMIGO2	1.90e-06	200	184	8	ed785a6d08ca2b350dc3307b587eadfb2886d1f9
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 PECAM1 EMILIN2 ZNF804A GLUL PLAUR PIK3R5 AMIGO2	1.90e-06	200	184	8	a443e475e7a10c26a6173d1af961de6219e0e567
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	FLI1 ROBO4 PECAM1 NCKAP5 NEDD4 PTPRG PLTP DISP1	1.90e-06	200	184	8	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	FLI1 ROBO4 PECAM1 NCKAP5 NEDD4 PTPRG PLTP DISP1	1.90e-06	200	184	8	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Myeloid-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 AOAH ADAM8 MS4A7 ASGR2 PIK3R5 PLTP	2.56e-06	146	184	7	69cbe8d4772f8e46a5e1a1cdca0e370308a97b4f
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 L1CAM AOAH EMILIN2 MS4A7 PLTP CCDC158	3.98e-06	156	184	7	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C FLI1 ROBO4 ADCY4 PECAM1 CTNNA3 PLAT	4.70e-06	160	184	7	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PCP2 PKD1L1 ADAMTSL3 MS4A7 SKA1 DNAH11	6.16e-06	109	184	6	87f647cfebbb7de725e434cc27058e1c6accbb90
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PCP2 PKD1L1 ADAMTSL3 MS4A7 SKA1 DNAH11	6.16e-06	109	184	6	6678036ff66c825a18d2506e33be421c27cf82e1
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P3\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PCP2 PKD1L1 ADAMTSL3 MS4A7 SKA1 DNAH11	6.16e-06	109	184	6	c9d1e69f9841135f4d114563a293a69a8ba5f965
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PCP2 PKD1L1 ADAMTSL3 MS4A7 SKA1 DNAH11	6.16e-06	109	184	6	e3696d84da1dcd15f15d0434ea9d1955f2af22d6
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IKZF2 SYNE1 L1CAM EMILIN2 ADAM8 MOB3C MOCOS	7.55e-06	172	184	7	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IKZF2 SYNE1 L1CAM EMILIN2 ADAM8 MOB3C MOCOS	7.55e-06	172	184	7	953b05f776348cff784e79c93df65841939d880f
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP6V1B1 MYH7B ADAMTSL3 ZNF804A PTPRG GNB4 PLEKHH2	9.10e-06	177	184	7	ac90e4ce5be304a5a7473736397327010f2d1999
ToppCell	10x5'-GI_large-bowel-Myeloid_Dendritic\|GI_large-bowel / Manually curated celltypes from each tissue	MRC1 MS4A7 SIGLEC7 ASGR2 CD302 GNB4 MOCOS	1.02e-05	180	184	7	400f48aa2851d89bf3b60d721bc0f635f3ad86eb
ToppCell	10x5'-GI_large-bowel-Myeloid_Dendritic-DC2\|GI_large-bowel / Manually curated celltypes from each tissue	MRC1 MS4A7 SIGLEC7 ASGR2 CD302 GNB4 MOCOS	1.02e-05	180	184	7	d4ebe67a2735e244c08b238320bbb441ca88ee6f
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NCKAP5 PLAT NTN1 CACNG4 PLEKHH2 TNR DNAH11	1.09e-05	182	184	7	a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PECAM1 ITGB4 LRRC3B HEY2 PLAT ATP2B2 AMIGO2	1.09e-05	182	184	7	aa113a0d2c1d28bda24cbb1221afd21b5628dc6d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 ROBO4 PECAM1 FOXP1 PLAUR GNB1 PLTP	1.09e-05	182	184	7	ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 ROBO4 PECAM1 FOXP1 PLAUR GNB1 PLTP	1.09e-05	182	184	7	97a805783a1f2b055c21307db250e3688674eff3
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NCKAP5 PLAT NTN1 CACNG4 PLEKHH2 TNR DNAH11	1.09e-05	182	184	7	831b5ce46b41efe01c4db6016c2f43148611373d
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C FLI1 ROBO4 ADCY4 SYNE1 PECAM1 PLAT	1.13e-05	183	184	7	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	CACNA1C MYH7B TENT5A CTNNA3 ADPRHL1 CNN1 CCSER1	1.17e-05	184	184	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NCKAP5 PLAT NTN1 CACNG4 PLEKHH2 TNR DNAH11	1.21e-05	185	184	7	2e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NCKAP5 PLAT NTN1 CACNG4 PLEKHH2 TNR DNAH11	1.21e-05	185	184	7	7aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	FLI1 THEMIS CEP85L TTC39C AOAH RHOH PIK3R5	1.21e-05	185	184	7	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NCKAP5 PLAT NTN1 CACNG4 PLEKHH2 TNR DNAH11	1.21e-05	185	184	7	fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	CACNA1C MYH7B TENT5A FBN2 CTNNA3 ADPRHL1 CCSER1	1.21e-05	185	184	7	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NCKAP5 PLAT NTN1 CACNG4 PLEKHH2 TNR DNAH11	1.21e-05	185	184	7	efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-C AHCYL2 DHRS7 FOXP1 NTN1 MPPED2 UNC80	1.21e-05	185	184	7	9438097e94219c1db922b8507e3a29106d32a923
ToppCell	Endoth-Lymph\|World / shred by cell class for parenchyma	MRC1 FLI1 ROBO4 ADCY4 WFS1 PKHD1L1 NTN1	1.21e-05	185	184	7	97a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 ADCY4 PECAM1 ITGB4 HEY2 PLAT NTN1	1.26e-05	186	184	7	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
Disease	Aphasia, Post-Traumatic	L1CAM PLAT	3.50e-05	2	175	2	C0750920
Disease	Dejerine-Lichtheim Phenomenon	L1CAM PLAT	3.50e-05	2	175	2	C0750921
Disease	Aphasia, Auditory Discriminatory	L1CAM PLAT	3.50e-05	2	175	2	C0750917
Disease	Aphasia, Commisural	L1CAM PLAT	3.50e-05	2	175	2	C0750918
Disease	Aphasia, Post-Ictal	L1CAM PLAT	3.50e-05	2	175	2	C0750919
Disease	Aphasia, Progressive	L1CAM PLAT	3.50e-05	2	175	2	C0338457
Disease	MICROCEPHALY 4, PRIMARY, AUTOSOMAL RECESSIVE	CEP152 KNL1	3.50e-05	2	175	2	C1858516
Disease	level of UL16-binding protein 6 in blood serum	ULBP2 RAET1L	3.50e-05	2	175	2	OBA_2043185
Disease	Aphasia, Mixed	L1CAM PLAT	3.50e-05	2	175	2	C0454576
Disease	Aphasia, Acquired	L1CAM PLAT	3.50e-05	2	175	2	C0003546
Disease	Aphasia	L1CAM PLAT	3.50e-05	2	175	2	C0003537
Disease	Kleefstra syndrome 1 (implicated_via_orthology)	EHMT2 EHMT1	3.50e-05	2	175	2	DOID:0060352 (implicated_via_orthology)
Disease	Aphasia, Semantic	L1CAM PLAT	3.50e-05	2	175	2	C0234482
Disease	Aphasia, Syntactical	L1CAM PLAT	3.50e-05	2	175	2	C0234484
Disease	Aphasia, Ageusic	L1CAM PLAT	3.50e-05	2	175	2	C0234462
Disease	Aphasia, Global	L1CAM PLAT	3.50e-05	2	175	2	C0234469
Disease	Aphasia, Intellectual	L1CAM PLAT	3.50e-05	2	175	2	C0234476
Disease	Aphasia, Functional	L1CAM PLAT	3.50e-05	2	175	2	C0234472
Disease	Aphasia, Graphomotor	L1CAM PLAT	3.50e-05	2	175	2	C0234474
Disease	Dysphasia	L1CAM PLAT	3.50e-05	2	175	2	C0973461
Disease	atypical femoral fracture, response to bisphosphonate	CACNA1C AOAH KCNG1 NTN1 PIK3R5	5.34e-05	68	175	5	EFO_0009958, EFO_0009960
Disease	ectonucleotide pyrophosphatase/phosphodiesterase family member 5 measurement	ENPP4 ENPP5	1.05e-04	3	175	2	EFO_0801560
Disease	Childhood Medulloblastoma	FLI1 EHMT1 CTNNB1 PRAME	1.23e-04	43	175	4	C0278510
Disease	Melanotic medulloblastoma	FLI1 EHMT1 CTNNB1 PRAME	1.23e-04	43	175	4	C1275668
Disease	Medullomyoblastoma	FLI1 EHMT1 CTNNB1 PRAME	1.23e-04	43	175	4	C0205833
Disease	Desmoplastic Medulloblastoma	FLI1 EHMT1 CTNNB1 PRAME	1.23e-04	43	175	4	C0751291
Disease	Adult Medulloblastoma	FLI1 EHMT1 CTNNB1 PRAME	1.23e-04	43	175	4	C0278876
Disease	specific developmental disorder (implicated_via_orthology)	FOXP2 FOXP1	2.08e-04	4	175	2	DOID:0060038 (implicated_via_orthology)
Disease	Flushing	C6orf89 BRAP	2.08e-04	4	175	2	HP_0031284
Disease	Medulloblastoma	FLI1 EHMT1 CTNNB1 PRAME	2.23e-04	50	175	4	C0025149
Disease	Neurodevelopmental Disorders	ILF2 PTK7 SYNGAP1 FOXP1 CTNNB1	2.36e-04	93	175	5	C1535926
Disease	Schizophrenia	CACNA1C FOXP2 HLA-C ADAMTSL3 ZNF804A DICER1 BRAP SYNGAP1 ARVCF TET1 GLUL PLAT CTNNB1 ZNF565 GNB3	2.65e-04	883	175	15	C0036341
Disease	Primary microcephaly	CEP152 CTNNB1 KNL1	2.91e-04	22	175	3	C0431350
Disease	viral infectious disease (implicated_via_orthology)	EHMT2 EHMT1	3.46e-04	5	175	2	DOID:934 (implicated_via_orthology)
Disease	Myelodysplastic syndrome	TET2 GNB1	3.46e-04	5	175	2	cv:C3463824
Disease	peritonitis (is_implicated_in)	FOXP1 PLAT	3.46e-04	5	175	2	DOID:8283 (is_implicated_in)
Disease	MYELODYSPLASTIC SYNDROME	TET2 GNB1	3.46e-04	5	175	2	614286
Disease	Vitiligo	FLI1 ATP8B1 IFIH1 RHOH FOXP1	3.47e-04	101	175	5	EFO_0004208
Disease	brain measurement, neuroimaging measurement	KIF6 FOXP2 TRIOBP NCKAP5 FAF1 FBN2 HEY2 FOXP1 NTN1 DNAH11 ANKS1A	4.70e-04	550	175	11	EFO_0004346, EFO_0004464
Disease	varicose veins (is_marker_for)	PECAM1 HEY2	5.16e-04	6	175	2	DOID:799 (is_marker_for)
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B2 ATP2B3	5.16e-04	6	175	2	DOID:0050429 (implicated_via_orthology)
Disease	acute promyelocytic leukemia (is_marker_for)	PLAT PRAME	5.16e-04	6	175	2	DOID:0060318 (is_marker_for)
Disease	body weight	TET2 CACNA1C KLHL24 FOXP2 C6orf89 AOAH E4F1 ADAMTSL3 WDR59 BRAP FBN2 IPO9 PTPRG UBXN7 CTNNA3 HEY2 MPPED2 CCSER1	5.31e-04	1261	175	18	EFO_0004338
Disease	platelet component distribution width	CACNA1C TRAF2 SYNE1 PECAM1 TENT5C RIPOR3 ENPP4 MPRIP UBE2O ARVCF ADPRHL1 TUBD1 ANKS1A	6.02e-04	755	175	13	EFO_0007984
Disease	basophil count	FLI1 IKZF2 HLA-C C6orf89 TENT5A TRIOBP BRAP ARVCF PLAUR TUBD1	6.52e-04	483	175	10	EFO_0005090
Disease	Drug-Induced Stevens Johnson Syndrome	HLA-C NEDD4 CTNNB1	6.69e-04	29	175	3	C1274933
Disease	Mycoplasma-Induced Stevens-Johnson Syndrome	HLA-C NEDD4 CTNNB1	6.69e-04	29	175	3	C3658301
Disease	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	HLA-C NEDD4 CTNNB1	6.69e-04	29	175	3	C3658302
Disease	Toxic Epidermal Necrolysis	HLA-C NEDD4 CTNNB1	6.69e-04	29	175	3	C0014518
Disease	brain connectivity measurement	KIF6 FOXP2 TRIOBP NCKAP5 FAF1 NEDD4 HEY2 FOXP1 NTN1	6.75e-04	400	175	9	EFO_0005210
Disease	clusterin measurement	C1RL PLTP	7.20e-04	7	175	2	EFO_0007655
Disease	atrioventricular septal defect (implicated_via_orthology)	MKS1 DNAH11	7.20e-04	7	175	2	DOID:0050651 (implicated_via_orthology)
Disease	Stevens-Johnson Syndrome	HLA-C NEDD4 CTNNB1	7.40e-04	30	175	3	C0038325
Disease	response to anti-thyroid drug, Drug-induced agranulocytosis	EHMT2 MOCOS	9.57e-04	8	175	2	EFO_0007838, HP_0012235
Disease	Colorectal Carcinoma	TET2 SYNE1 ZDHHC7 ADAMTSL3 ZNF804A FBN2 SIGLEC7 LDB1 LRRC3B GNB4 CTNNB1 PIK3R5	1.04e-03	702	175	12	C0009402
Disease	retinal vasculature measurement	CACNA1C NCKAP5 CTNNA3 GLUL CTNNB1 GNB2 GNB3 MPPED2 KNL1 CCSER1	1.09e-03	517	175	10	EFO_0010554
Disease	Headache, glucose measurement	SGSM1 FAF1	1.23e-03	9	175	2	EFO_0004468, HP_0002315
Disease	urate measurement, bone density	CASP8AP2 ATP6V1B1 KIF6 SYNE1 AOAH RIPOR3 PTPRG EHMT2 CD302 ATP2B2 DNAH11	1.23e-03	619	175	11	EFO_0003923, EFO_0004531
Disease	Tetralogy of Fallot	C6orf89 BRAP	1.53e-03	10	175	2	HP_0001636
Disease	platelet glycoprotein ib alpha chain measurement	C6orf89 BRAP	1.53e-03	10	175	2	EFO_0020645
Disease	plasma trimethylamine N-oxide measurement	CEP85L ENPP4	1.53e-03	10	175	2	EFO_0005691
Disease	f-box/LRR-repeat protein 4 measurement	C1RL PLTP	1.53e-03	10	175	2	EFO_0802538
Disease	liver fibrosis measurement	MRC1 C6orf89 TENT5A BRAP	1.74e-03	86	175	4	EFO_0010576
Disease	alanine measurement	TENT5C PDXDC2P FOXP1 CCSER1	1.74e-03	86	175	4	EFO_0009765
Disease	neuroimaging measurement	MRC1 KIF6 FOXP2 NCKAP5 FAF1 PTK7 FBN2 HEY2 PDXDC2P FOXP1 NTN1 TUBD1 MPPED2 DNAH11 ANKS1A	1.84e-03	1069	175	15	EFO_0004346
Disease	Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement	HLA-C DNAH11	1.86e-03	11	175	2	EFO_0009923
Disease	forced expiratory volume, body mass index	C6orf89 BRAP	1.86e-03	11	175	2	EFO_0004314, EFO_0004340
Disease	glucose measurement	TET2 SGSM1 WFS1 TENT5C SYNGAP1 EHMT2 PLEKHH2 TRIM48	2.03e-03	380	175	8	EFO_0004468
Disease	chronic musculoskeletal pain	FOXP2 FAF2	2.22e-03	12	175	2	EFO_0022195
Disease	polychlorinated biphenyls measurement, gestational serum measurement	NCKAP5 CCSER1	2.22e-03	12	175	2	EFO_0007042, EFO_0007964
Disease	hypertrophic cardiomyopathy	CEP85L NCKAP5 ADPRHL1 TRIM48	2.23e-03	92	175	4	EFO_0000538
Disease	selective IgA deficiency disease	NCKAP5 IFIH1 FOXP1	2.58e-03	46	175	3	EFO_1001929
Disease	prostate carcinoma	TET2 IKZF2 HLA-C ZDHHC7 NEDD4 RIF1 FOXP1 CEP152 PLEKHH2 KNL1 MOCOS AMIGO2 DNAH11	2.63e-03	891	175	13	EFO_0001663
Disease	Salivary Gland Neoplasms	ZIM2 ITGB4 CTNNB1	2.75e-03	47	175	3	C0036095
Disease	PR interval	CEP85L EMILIN2 NCKAP5 FAF1 FBN2 FOXP1 ADPRHL1 MPPED2 DNAH11	2.91e-03	495	175	9	EFO_0004462
Disease	urokinase plasminogen activator surface receptor measurement	ASGR2 PLAUR	3.04e-03	14	175	2	EFO_0010932
Disease	tetralogy of Fallot (implicated_via_orthology)	MKS1 HEY2	3.04e-03	14	175	2	DOID:6419 (implicated_via_orthology)
Disease	Kartagener syndrome (implicated_via_orthology)	DNAI2 DNAH11	3.04e-03	14	175	2	DOID:0050144 (implicated_via_orthology)
Disease	actinic keratosis	SPATA33 FOXP1	3.04e-03	14	175	2	EFO_0002496
Disease	Spastic Paraplegia, Hereditary	L1CAM TECPR2	3.04e-03	14	175	2	C0037773
Disease	attention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia	CACNA1C SYNE1 ZNF804A SPATA33	3.12e-03	101	175	4	EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Disease	QRS amplitude, QRS complex	CEP85L GOSR2 MPPED2	3.28e-03	50	175	3	EFO_0005054, EFO_0007742
Disease	Ischemic stroke	PGLYRP3 GOSR2 ADAMTSL3 EPG5 PTPRG TNR DNAH11	3.32e-03	324	175	7	HP_0002140
Disease	Mood Disorders	CACNA1C WFS1 ZNF804A GLUL GNB3	3.35e-03	168	175	5	C0525045
Disease	lung non-small cell carcinoma (is_marker_for)	IKZF2 SOX30 PECAM1 L1CAM FOXP1	3.43e-03	169	175	5	DOID:3908 (is_marker_for)
Disease	tumor necrosis factor measurement	C6orf89 BRAP	3.49e-03	15	175	2	EFO_0010834
Disease	distal arthrogryposis (implicated_via_orthology)	MYH7B FBN2	3.49e-03	15	175	2	DOID:0050646 (implicated_via_orthology)
Disease	Autosomal recessive primary microcephaly	CEP152 KNL1	3.49e-03	15	175	2	cv:C3711387
Disease	nasopharynx carcinoma (is_implicated_in)	TET2 CR2	3.49e-03	15	175	2	DOID:9261 (is_implicated_in)
Disease	autism spectrum disorder, schizophrenia	CACNA1C HLA-C ZNF804A SYNGAP1 EHMT2 FOXP1 ATP2B2	3.49e-03	327	175	7	EFO_0003756, MONDO_0005090
Disease	intraocular pressure measurement	C6orf89 TRIOBP BRAP NEDD4 FBN2 CPXM1 FOXP1 ADPRHL1 TRIM48	3.49e-03	509	175	9	EFO_0004695
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	TET2 C6orf89 BRAP	3.66e-03	52	175	3	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	idiopathic scoliosis (implicated_via_orthology)	KIF6 PTK7	3.97e-03	16	175	2	DOID:0060250 (implicated_via_orthology)
Disease	Vitiligo	IFIH1 FOXP1	4.49e-03	17	175	2	C0042900
Disease	Astrocytosis	ITGB4 TNR	4.49e-03	17	175	2	C3887640
Disease	Antibody Deficiency Syndrome	CACNA1C EPG5	4.49e-03	17	175	2	C0003257
Disease	Gliosis	ITGB4 TNR	4.49e-03	17	175	2	C0017639
Disease	hepatocellular carcinoma (is_implicated_in)	TET2 TRAF7 SOX30 DICER1 CTNNB1	4.59e-03	181	175	5	DOID:684 (is_implicated_in)
Disease	Autistic Disorder	CACNA1C ROBO4 FOXP2 PECAM1 SYNGAP1 PLAUR	4.78e-03	261	175	6	C0004352
Disease	alcohol dependence	CACNA1C C6orf89 FAF1 BRAP ANKS1A	4.80e-03	183	175	5	MONDO_0007079

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRCTADMNITAEHSN	PTPRG	856	P23470
LMCVISASVHGVDQR	BEST4	106	Q8NFU0
AACQSLASVRHMAET	EPG5	2311	Q9HCE0
MDESVNGILTTLCNH	BRAP	271	Q7Z569
ESGCMHITFRDSNER	CEP152	1516	O94986
NCRSVISHSVTSDMQ	ARFGAP3	311	Q9NP61
MEDCNVHSAASILAS	ARVCF	1	O00192
TVQENAGSISCSMRH	BTNL8	196	Q6UX41
ACQMELLHSNGSQRT	ASGR2	161	P07307
TCIMNHEAVSASGRK	ADAM18	341	Q9Y3Q7
DVRNQCTDHGADMIS	CD302	51	Q8IX05
QGFHAVCINTEDSQM	ARL9	51	Q6T311
LAMQDTSRRPCHSQD	CPXM1	541	Q96SM3
DRMSTENAAILTHCE	DNAH11	3476	Q96DT5
QQDAERSCSHLGTMV	ADCY4	946	Q8NFM4
HQGDSLECTAMTVQI	COPE	141	O14579
NCETSTMNIDRNITH	EHMT2	956	Q96KQ7
LMVHCDSKTGNANTD	AMIGO2	306	Q86SJ2
NAISCHSLDSMASGR	ANKS1A	366	Q92625
DQEARCSHISRMPNS	CCSER1	586	Q9C0I3
VSAMCSHSSGAVNQD	ADAM8	306	P78325
SSLENHDQMSVNCRT	DICER1	1141	Q9UPY3
HDQMSVNCRTLLSES	DICER1	1146	Q9UPY3
IQCSISMSEHEANSE	DNAI2	51	Q9GZS0
NNGDQSHKMTTSRCV	DHRS7	256	Q9Y394
ENSLLVRSVDNTMHC	CASP8AP2	656	Q9UKL3
GQETMTVTLLDANHC	DCLRE1B	86	Q9H816
SMCNVDNSRIRSHPQ	DISP1	321	Q96F81
VRHLDACETMGNATA	ATP2B2	481	Q01814
RHLDACETMGNATAI	ATP2B3	456	Q16720
LAVCHTVMVDRTDGQ	ATP8B1	531	O43520
MVHGVTTEECQAALQ	TNK2	966	Q07912
QNEQEAVCTDSHTDM	NTN1	196	O95631
QHQLDTSVSIEECMS	RBM41	31	Q96IZ5
SHVQGDRMEGQRCSL	PCP2	31	Q8IVA1
QVHNSTVQASMERLC	AOAH	56	P28039
HLSTCATQREAAAMT	HEY2	156	Q9UBP5
VCISDTHSRTDGIQM	MPPED2	61	Q15777
SAADIAATVQHTMAC	OSGEPL1	281	Q9H4B0
TMQNTNDVETARCTA	CTNNB1	201	P35222
QATCERGFAAMEETH	MPRIP	721	Q6WCQ1
MSQDQESPRCTHDQH	MAGEB16	1	A2A368
MSLVSQNARHCSAEI	MAGEE2	1	Q8TD90
HSNFVSLDCDQGSMV	LDB1	151	Q86U70
MHRTSACLPSSQNVD	NEDD4	416	P46934
LMGSEVTQIACGRQH	HERC3	291	Q15034
GEVCTMSSFLDREQH	DSG4	216	Q86SJ6
QSEDGSHTLQRMSGC	HLA-C	111	P10321
ADSMVALRTASQHCG	MS4A7	136	Q9GZW8
HFCSQGVITVDNMND	MYH7B	356	A7E2Y1
ENRHGTRCAGEVAAM	PCSK4	196	Q6UW60
VSNVSCQASVSRMHA	PLTP	141	P55058
SVCSQMLRGLQSHSV	PGLYRP3	61	Q96LB9
CQARIISGIHMQTSE	PECAM1	206	P16284
NMTPSAVGRERHSCD	PDXDC2P	411	Q6P474
NVIITSDHGMTQCSQ	ENPP4	231	Q9Y6X5
SDHGMTQCSQDRLIN	ENPP4	236	Q9Y6X5
TSDHGMTQCSEERLI	ENPP5	236	Q9UJA9
HALDDRSTAQCRVQM	FOXP2	371	O15409
HALDDRSTAQCRVQM	FOXP1	331	Q9H334
IAETPMNQASTRSHC	KIF6	211	Q6ZMV9
SCGQDDMEITRSHTT	KNL1	1146	Q8NG31
PSDTMVTQCEARNRH	L1CAM	396	P32004
SMCRQTFIGHESDIN	GNB2	216	P62879
HDNRVSCLGVTADGM	GNB3	311	P16520
GMCRQSFTGHVSDIN	GNB4	216	Q9HAV0
QVHEIQSCMGRLETA	GOSR2	11	O14653
TGACQRHLGISNEMV	MOCOS	426	Q96EN8
SLREEEEQGHCSQMC	KCNG1	251	Q9UIX4
CTLQQVLRSMASNHE	LRRC3B	151	Q96PB8
RSCDNISDTGIMHLA	FBXL14	261	Q8N1E6
DSVCGETHRALQGAM	GOLGA2	791	Q08379
TCDNELSPEREHSNM	IKZF2	11	Q9UKS7
MSRNDERCHLDTTGT	ITGB4	281	P16144
RTSESRDLCHMANGI	ING2	156	Q9H160
LSSHTSEEGVQCSRM	PLEKHH2	306	Q8IVE3
HMDGSSCELQVINFT	NT5DC4	371	Q86YG4
HTSRLVEVANLACSM	CTNNA3	421	Q9UI47
FSHEEVQMILCGNQS	HECTD1	2481	Q9ULT8
HVQNTFSRQENCGMS	KLHL24	526	Q6TFL4
ICAMVTTQHREDVGI	C2CD3	1136	Q4AC94
HTQCSPSMNAEENSR	CACNA1C	1356	Q13936
IMNGSRVIRCHTDNT	CR2	821	P20023
TCVDQSEHTMVLRCQ	C2CD2L	141	O14523
SSAHICNGTNLTMDD	CACNG4	36	Q9UBN1
GMCRQTFTGHESDIN	GNB1	216	P62873
DHMNGSRESPVDCSV	FLI1	71	Q01543
CESGNFRVHTVMTLE	ILF2	291	Q12905
SVSCLDESLGHNSNM	IFIH1	266	Q9BYX4
SDNMFCVGDETQRHS	C1RL	416	Q9NZP8
TLIEVSVECGRMTHN	ADPRHL1	151	Q8NDY3
RSMNCSAEETENDHS	CEP85L	751	Q5SZL2
SDERGAHIMNSTCAA	CCP110	486	O43303
TVMSHGCENFNTRDS	C17orf80	326	Q9BSJ5
AVAQCTLHTDDNATM	IPO9	696	Q96P70
DVTHLQKEMSNCRAG	EMILIN2	621	Q9BXX0
CSSEGSRENLLHQAM	E4F1	361	Q66K89
TMCNRHFGSVVAQTI	FAF1	426	Q9UNN5
TESSLRSDMCHRSNN	CCDC158	946	Q5M9N0
VDHDECTTTNMCLNG	FBN2	616	P35556
ETVDLVRQTGHQCGM	C6orf89	16	Q6UWU4
RGCHVNDRDGLTDMT	CLIP3	106	Q96DZ5
QISQEMGSCSFSIHQ	SCARA3	166	Q6AZY7
CRSGTSVLHMNSRQA	SLFN13	136	Q68D06
MATESVDHELGRCTN	EHMT1	541	Q9H9B1
ANILEACEHMTSDQR	EXOSC3	251	Q9NQT5
AVQNGDMETSHGICR	IPO13	296	O94829
CLSLNHVSTGQMEFR	PKD1L1	1456	Q8TDX9
DSILSMGAEAHVNTC	MOB3C	171	Q70IA8
MSNRVVCREASHAGS	MEMO1	1	Q9Y316
SHCQENDGSVEMRDV	NXF2	56	Q9GZY0
QDAASNMLVAICRHS	MROH5	186	Q6ZUA9
ICQRHNSSINATTVM	MRC1	921	P22897
GCHTNFSTKAMREEN	GLUL	251	P15104
SCNLGAAREHMQAVT	ATP6V1B1	16	P15313
FLSSEEQMCGIHRET	TRIM48	101	Q8IWZ4
CNMGHSNTEIDVASL	AHCYL2	476	Q96HN2
ASASCHQEAVEQTIM	PPP4R1	901	Q8TF05
QCESLISMHSVSQED	SLC35F5	506	Q8WV83
MASSDLEQLCSHVNE	SKA1	1	Q96BD8
NCRLSEGDVMHLSQS	PRAME	331	P78395
LLHMEIDNSQACSSA	STRIP2	171	Q9ULQ0
EVKQNTTASGCELMH	SYNE1	2906	Q8NF91
LDESHVNSRMGCQAT	SYNE1	3666	Q8NF91
RTDSACSLKQMVHEG	SYNE1	8071	Q8NF91
SHIIESNCQMRTLDS	NCKAP5	1706	O14513
ECVSDNQVHLSESTM	RIF1	1336	Q5UIP0
TQTDQREMGPHRASC	RHOH	116	Q15669
TVSDMNRVLGSDTNC	PNMA3	116	Q9UL41
QDLTGIESMDQCRHT	FAF2	21	Q96CS3
ESSMCQSNSRDHLSD	NCOA3	581	Q9Y6Q9
QSSVTVQEGMCVHVR	SIGLEC7	31	Q9Y286
MSVSRLSCDDVTINH	OR56A3	186	Q8NH54
CERSLAEMESSHQQV	TRIOBP	2111	Q9H2D6
HSENSRSCENMNGTS	SOX30	681	O94993
MCVATNSAGHRESRA	ROBO4	206	Q8WZ75
NESTVCLMNHERRQT	TENT5B	351	Q96A09
RRVVNESTVCLMGHE	TENT5C	311	Q5VWP2
ESTVCLMGHERRQTL	TENT5C	316	Q5VWP2
HNMNNGSTVVCTLTR	TET1	1676	Q8NFU7
HNTTSNMGCTLILED	ASPA	116	P45381
EHCDTLNVSLQMGSN	CNN1	236	P51911
MVTHAAGARTFCEEQ	SPATA33	1	Q96N06
VAMTAEACSRQHRLD	TRAF2	296	Q12933
GEIMVSCAVARNHQT	THEMIS	146	Q8N1K5
DSHSSQGLCSMRENE	TUBD1	26	Q9UJT1
SIQSSEMIATNTRHC	UHRF1BP1L	601	A0JNW5
AQDGAQMVCKAHTRT	nan	106	Q9BRP9
MPLCVSAHNRNTITD	USPL1	771	Q5W0Q7
ECGMAFIRSSQLTEH	ZNF565	491	Q8N9K5
CTSQHLLNRTVTDNM	PLAT	476	P00750
GSSDMSCERGRHQSL	PLAUR	121	Q03405
SVCLHEEQTQAAGMV	ZNF778	16	Q96MU6
QMSRCDQGHKGTTTA	UNC80	2426	Q8N2C7
NLEEHCQRMTTAASE	MKS1	136	Q9NXB0
CTASSLAEHQANLRM	SYNGAP1	531	Q96PV0
MQPGATTCTEDRIQH	PIK3R5	1	Q8WYR1
CRARQEHTSAESLME	RIPOR3	551	Q96MK2
GDSAQSTACDRHMAV	PLAC9	31	Q5JTB6
DISQAMNPIDSCARH	SPATA31D1	281	Q6ZQQ2
ESERICTLVHTAMDN	TNR	941	Q92752
DVVRHMRSTDSQCGT	UBE2O	151	Q9C0C9
MRSTDSQCGTVIDVN	UBE2O	156	Q9C0C9
DNMICTQTLLRHQGS	TRAF7	631	Q6Q0C0
LEMSGCSERVHVQQA	TECPR2	366	O15040
LQARMSCEQKAEGHS	RAET1L	121	Q5VY80
SEDSITCHIDPQNSM	PKHD1L1	1611	Q86WI1
TCHIDPQNSMDVGIR	PKHD1L1	1616	Q86WI1
ALCIQKRHSSGSMDD	SGSM1	221	Q2NKQ1
HLSEEEMARTFNCGV	GART	721	P22102
DSQATAMSVDCLGQH	WDR59	16	Q6PJI9
METDSRHTVICQGES	ZIM2	236	Q9NZV7
NSSNLCMHQRVHTGE	ZNF664	126	Q8N3J9
ASESVGKHMLEACNN	UBXN7	26	O94888
QRQIVHTGEASFMCD	ZNF16	226	P17020
VMFGTQIHSICNDET	ZDHHC7	236	Q9NXF8
ITETGRQVTLMCHQT	TRBV10-2	31	A0A0K0K1G8
MASTITGSQDCIVNH	ZNF239	1	Q16600
HTREMGRISQVENSC	ZNF614	561	Q8N883
MSQACHEVDDSSVVG	TTC39C	471	Q8N584
LQARMSCEQKAEGHS	ULBP2	121	Q9BZM5
IVRVGSAHRMVTNCS	TBX19	171	O60806
AIRHTACNEQQRTTM	UBR4	2216	Q5T4S7
HNMQNGSTLVCTLTR	TET2	1386	Q6N021
VVNESTVCLMGHERR	TENT5A	361	Q96IP4
CTQVALGMEHLSNNR	PTK7	911	Q13308
VCSSNQNRSMEAHNI	SSU72	11	Q9NP77
TQCENTSRNNSIHAM	ZNF114	251	Q8NC26
TNMARTQILCSHLEG	WFS1	681	O76024
SCSQDHRSLVLQNDM	ZNF804A	731	Q7Z570
MNSTSEDVAASHRCD	ZBED4	1036	O75132
TQQTVNDSLCDMVHR	ADAMTSL3	676	P82987
EMLTGQRLCHSESHN	KLHL32	11	Q96NJ5
CNVDIATTEALSMAH	MX2	266	P20592