Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	RAB9B DNAH3 ABCA2 TDRD9 KIF26A LRRK2 CCT2 GIMAP7 XRCC5 TRIP13 DDX27 RAB9A ABCB10 MACF1 GNA11 GNAQ DNAH9 RHOF DYNC1H1 DNAH11	1.41e-07	775	130	20	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	RAB9B DNAH3 ABCA2 TDRD9 KIF26A LRRK2 CCT2 GIMAP7 XRCC5 TRIP13 DDX27 RAB9A ABCB10 MACF1 GNA11 GNAQ DNAH9 RHOF DYNC1H1 DNAH11	4.99e-07	839	130	20	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	RAB9B DNAH3 ABCA2 TDRD9 KIF26A LRRK2 CCT2 GIMAP7 XRCC5 TRIP13 DDX27 RAB9A ABCB10 MACF1 GNA11 GNAQ DNAH9 RHOF DYNC1H1 DNAH11	5.08e-07	840	130	20	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RAB9B DNAH3 ABCA2 TDRD9 KIF26A LRRK2 CCT2 GIMAP7 XRCC5 TRIP13 DDX27 RAB9A ABCB10 MACF1 GNA11 GNAQ DNAH9 RHOF DYNC1H1 DNAH11	5.08e-07	840	130	20	GO:0016818
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DNAH9 DYNC1H1 DNAH11	4.89e-06	18	130	4	GO:0008569
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH3 ABCA2 TDRD9 KIF26A CCT2 XRCC5 TRIP13 DDX27 ABCB10 MACF1 DNAH9 DYNC1H1 DNAH11	6.27e-06	441	130	13	GO:0016887
GeneOntologyMolecularFunction	microtubule motor activity	DNAH3 KIF26A STARD9 DNAH9 DYNC1H1 DNAH11	6.32e-06	70	130	6	GO:0003777
GeneOntologyMolecularFunction	guanyl ribonucleotide binding	RAB9B PDE6C LRRK2 GIMAP7 SRPRB SH3BP4 RANBP17 RAB9A GUCY1A1 GNA11 GNAQ RHOF	3.05e-05	439	130	12	GO:0032561
GeneOntologyMolecularFunction	guanyl nucleotide binding	RAB9B PDE6C LRRK2 GIMAP7 SRPRB SH3BP4 RANBP17 RAB9A GUCY1A1 GNA11 GNAQ RHOF	3.05e-05	439	130	12	GO:0019001
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH3 DNAH9 DYNC1H1 DNAH11	3.11e-05	28	130	4	GO:0051959
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH3 ABCA2 TDRD9 KIF26A CCT2 XRCC5 TRIP13 DDX27 ABCB10 STARD9 MACF1 DNAH9 DYNC1H1 DNAH11	4.80e-05	614	130	14	GO:0140657
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH3 DNAH9 DYNC1H1 DNAH11	9.59e-05	37	130	4	GO:0045505
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH3 KIF26A STARD9 DNAH9 DYNC1H1 DNAH11	1.23e-04	118	130	6	GO:0003774
GeneOntologyMolecularFunction	GTP binding	RAB9B LRRK2 GIMAP7 SRPRB RANBP17 RAB9A GUCY1A1 GNA11 GNAQ RHOF	2.76e-04	397	130	10	GO:0005525
GeneOntologyMolecularFunction	alkylglycerophosphoethanolamine phosphodiesterase activity	GNA11 GNAQ	4.15e-04	5	130	2	GO:0047391
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	PDE6C APEX1 GNA11 GNAQ PLD2	4.32e-04	97	130	5	GO:0008081
GeneOntologyMolecularFunction	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	EDEM3 EDEM2	1.15e-03	8	130	2	GO:0004571
GeneOntologyMolecularFunction	double-stranded telomeric DNA binding	APEX1 XRCC5	1.47e-03	9	130	2	GO:0003691
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	DNAH3 DPYSL3 WAS KIF26A KRT74 KRT83 TOGARAM1 TSC1 CCT2 SRPRB SPTBN4 KRT75 MACF1 EIF3A DNAH9 CEP170B DYNC1H1 DNAH11	1.17e-05	899	130	18	GO:0099513
GeneOntologyCellularComponent	supramolecular fiber	CACNA1D DNAH3 DPYSL3 WAS KIF26A KRT74 KRT83 TOGARAM1 TSC1 CCT2 SRPRB SPTBN4 KRT75 MACF1 EIF3A DNAH9 CEP170B DYNC1H1 DNAH11	1.26e-04	1179	130	19	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	CACNA1D DNAH3 DPYSL3 WAS KIF26A KRT74 KRT83 TOGARAM1 TSC1 CCT2 SRPRB SPTBN4 KRT75 MACF1 EIF3A DNAH9 CEP170B DYNC1H1 DNAH11	1.37e-04	1187	130	19	GO:0099081
GeneOntologyCellularComponent	dynein complex	DNAH3 DNAH9 DYNC1H1 DNAH11	3.55e-04	54	130	4	GO:0030286
GeneOntologyCellularComponent	microtubule	DNAH3 KIF26A TOGARAM1 CCT2 SRPRB MACF1 EIF3A DNAH9 CEP170B DYNC1H1 DNAH11	5.05e-04	533	130	11	GO:0005874
GeneOntologyCellularComponent	cell cortex	SPTBN2 HIP1R TSC1 GRM7 SPTBN4 HMCN2 MACF1 DYNC1H1 ARHGAP33	5.30e-04	371	130	9	GO:0005938
GeneOntologyCellularComponent	interphotoreceptor matrix	IMPG1 VCAN	5.66e-04	6	130	2	GO:0033165
GeneOntologyCellularComponent	cell body	CACNA1D DPYSL3 SPTBN2 LRRK2 HIP1R CCT2 GRM7 PITPNM1 SPTBN4 HMCN2 ZPR1 KCNJ14 MAST1 GNAQ DYNC1H1	6.68e-04	929	130	15	GO:0044297
GeneOntologyCellularComponent	Cdc73/Paf1 complex	CTR9 CDC73	7.90e-04	7	130	2	GO:0016593
GeneOntologyCellularComponent	lipid droplet	LPCAT1 TSC1 GIMAP7 PITPNM1 PNPLA3	7.96e-04	116	130	5	GO:0005811
GeneOntologyCellularComponent	spectrin	SPTBN2 SPTBN4	1.34e-03	9	130	2	GO:0008091
Domain	P-loop_NTPase	RAB9B DNAH3 ABCA2 TDRD9 KIF26A LRRK2 CMPK2 GIMAP7 TRIP13 SRPRB DDX27 RAB9A ABCB10 STARD9 GNA11 GNAQ DNAH9 RHOF DYNC1H1 DNAH11	1.86e-06	848	131	20	IPR027417
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH9 DYNC1H1 DNAH11	2.19e-06	14	131	4	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH9 DYNC1H1 DNAH11	2.19e-06	14	131	4	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH9 DYNC1H1 DNAH11	2.19e-06	14	131	4	IPR013602
Domain	DHC_N2	DNAH3 DNAH9 DYNC1H1 DNAH11	2.19e-06	14	131	4	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH9 DYNC1H1 DNAH11	2.19e-06	14	131	4	IPR011704
Domain	MT	DNAH3 DNAH9 DYNC1H1 DNAH11	2.19e-06	14	131	4	PF12777
Domain	AAA_8	DNAH3 DNAH9 DYNC1H1 DNAH11	2.19e-06	14	131	4	PF12780
Domain	AAA_5	DNAH3 DNAH9 DYNC1H1 DNAH11	2.19e-06	14	131	4	PF07728
Domain	DHC_fam	DNAH3 DNAH9 DYNC1H1 DNAH11	2.97e-06	15	131	4	IPR026983
Domain	Dynein_heavy	DNAH3 DNAH9 DYNC1H1 DNAH11	2.97e-06	15	131	4	PF03028
Domain	Dynein_heavy_dom	DNAH3 DNAH9 DYNC1H1 DNAH11	2.97e-06	15	131	4	IPR004273
Domain	ARM-like	COPB1 TNPO2 LRRK2 TOGARAM1 COPG2 HUWE1 TEX10 RANBP17 FHOD1 PDS5A ARMC6	3.22e-06	270	131	11	IPR011989
Domain	-	COPB1 TNPO2 LRRK2 TOGARAM1 COPG2 TEX10 RANBP17 FHOD1 PDS5A ARMC6	3.79e-06	222	131	10	1.25.10.10
Domain	-	RAB9B DNAH3 ABCA2 TDRD9 LRRK2 CMPK2 GIMAP7 TRIP13 SRPRB DDX27 RAB9A ABCB10 GNA11 GNAQ DNAH9 RHOF DYNC1H1 DNAH11	4.70e-06	746	131	18	3.40.50.300
Domain	DHC_N1	DNAH9 DYNC1H1 DNAH11	1.84e-05	8	131	3	PF08385
Domain	Dynein_heavy_dom-1	DNAH9 DYNC1H1 DNAH11	1.84e-05	8	131	3	IPR013594
Domain	Glyco_hydro_47	EDEM3 USF3 EDEM2	1.84e-05	8	131	3	IPR001382
Domain	ARM-type_fold	COPB1 TNPO2 LRRK2 TOGARAM1 COPG2 HUWE1 TEX10 RANBP17 FHOD1 PDS5A ARMC6	2.73e-05	339	131	11	IPR016024
Domain	AAA	DNAH3 ABCA2 TRIP13 ABCB10 DNAH9 DYNC1H1 DNAH11	7.04e-05	144	131	7	SM00382
Domain	AAA+_ATPase	DNAH3 ABCA2 TRIP13 ABCB10 DNAH9 DYNC1H1 DNAH11	7.04e-05	144	131	7	IPR003593
Domain	HEAT_REPEAT	TNPO2 TOGARAM1 COPG2 TEX10 PDS5A	1.32e-04	70	131	5	PS50077
Domain	Spectrin_bsu	SPTBN2 SPTBN4	2.90e-04	4	131	2	IPR016343
Domain	Gprotein_alpha_Q	GNA11 GNAQ	2.90e-04	4	131	2	IPR000654
Domain	Spectrin	SPTBN2 SPTBN4 MACF1	5.39e-04	23	131	3	PF00435
Domain	ACTININ_2	SPTBN2 SPTBN4 MACF1	5.39e-04	23	131	3	PS00020
Domain	ACTININ_1	SPTBN2 SPTBN4 MACF1	5.39e-04	23	131	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN2 SPTBN4 MACF1	5.39e-04	23	131	3	IPR001589
Domain	Keratin_2_head	KRT74 KRT83 KRT75	6.13e-04	24	131	3	IPR032444
Domain	Keratin_2_head	KRT74 KRT83 KRT75	6.13e-04	24	131	3	PF16208
Domain	Keratin_II	KRT74 KRT83 KRT75	7.79e-04	26	131	3	IPR003054
Domain	FHA	STARD9 MKI67 CEP170B	9.72e-04	28	131	3	SM00240
Domain	Glyco_hydro_47	EDEM3 EDEM2	1.00e-03	7	131	2	PF01532
Domain	-	EDEM3 EDEM2	1.00e-03	7	131	2	1.50.10.50
Domain	Spectrin_repeat	SPTBN2 SPTBN4 MACF1	1.08e-03	29	131	3	IPR002017
Domain	FHA	STARD9 MKI67 CEP170B	1.31e-03	31	131	3	PF00498
Domain	SPEC	SPTBN2 SPTBN4 MACF1	1.44e-03	32	131	3	SM00150
Domain	Spectrin/alpha-actinin	SPTBN2 SPTBN4 MACF1	1.44e-03	32	131	3	IPR018159
Domain	PH_dom-spectrin-type	SPTBN2 SPTBN4	1.70e-03	9	131	2	IPR001605
Domain	-	STARD9 MKI67 CEP170B	2.03e-03	36	131	3	2.60.200.20
Domain	FHA_dom	STARD9 MKI67 CEP170B	2.03e-03	36	131	3	IPR000253
Domain	WWE	HUWE1 PARP14	3.08e-03	12	131	2	PF02825
Domain	WWE-dom	HUWE1 PARP14	3.08e-03	12	131	2	IPR004170
Domain	WWE	HUWE1 PARP14	3.08e-03	12	131	2	PS50918
Domain	uDENN	DENND2A SBF1	4.20e-03	14	131	2	SM00800
Domain	Clathrin/coatomer_adapt-like_N	COPB1 COPG2	4.83e-03	15	131	2	IPR002553
Domain	uDENN	DENND2A SBF1	4.83e-03	15	131	2	PF03456
Domain	Adaptin_N	COPB1 COPG2	4.83e-03	15	131	2	PF01602
Domain	IBN_N	TNPO2 RANBP17	4.83e-03	15	131	2	PF03810
Domain	GproteinA_insert	GNA11 GNAQ	5.49e-03	16	131	2	IPR011025
Domain	DENN	DENND2A SBF1	5.49e-03	16	131	2	SM00799
Domain	IBN_N	TNPO2 RANBP17	5.49e-03	16	131	2	SM00913
Domain	-	GNA11 GNAQ	5.49e-03	16	131	2	1.10.400.10
Domain	DENN	DENND2A SBF1	5.49e-03	16	131	2	PF02141
Domain	dDENN	DENND2A SBF1	5.49e-03	16	131	2	PF03455
Domain	G-alpha	GNA11 GNAQ	5.49e-03	16	131	2	PF00503
Domain	UDENN	DENND2A SBF1	5.49e-03	16	131	2	PS50946
Domain	DDENN	DENND2A SBF1	5.49e-03	16	131	2	PS50947
Domain	dDENN	DENND2A SBF1	5.49e-03	16	131	2	SM00801
Domain	dDENN_dom	DENND2A SBF1	5.49e-03	16	131	2	IPR005112
Domain	uDENN_dom	DENND2A SBF1	5.49e-03	16	131	2	IPR005113
Domain	DENN	DENND2A SBF1	5.49e-03	16	131	2	PS50211
Domain	DENN_dom	DENND2A SBF1	5.49e-03	16	131	2	IPR001194
Domain	Ald_DH_CS_GLU	ALDH5A1 ALDH7A1	5.49e-03	16	131	2	IPR029510
Domain	G_alpha	GNA11 GNAQ	5.49e-03	16	131	2	SM00275
Domain	SMAD_FHA_domain	STARD9 MKI67 CEP170B	5.80e-03	52	131	3	IPR008984
Domain	Importin-beta_N	TNPO2 RANBP17	6.20e-03	17	131	2	IPR001494
Domain	Gprotein_alpha_su	GNA11 GNAQ	6.20e-03	17	131	2	IPR001019
Domain	Ald_DH_CS_CYS	ALDH5A1 ALDH7A1	6.20e-03	17	131	2	IPR016160
Domain	ALDEHYDE_DEHYDR_CYS	ALDH5A1 ALDH7A1	6.94e-03	18	131	2	PS00070
Domain	ALDEHYDE_DEHYDR_GLU	ALDH5A1 ALDH7A1	6.94e-03	18	131	2	PS00687
Pathway	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	LPCAT1 PLB1 PITPNM1 GPD1L SLC44A1 PNPLA3 PLD2	3.10e-05	120	105	7	MM14585
Pathway	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	LPCAT1 PLB1 PITPNM1 GPD1L SLC44A1 PNPLA3 PLD2	4.70e-05	128	105	7	M706
Pathway	REACTOME_PHOSPHOLIPID_METABOLISM	LPCAT1 PLB1 PITPNM1 GPD1L SLC44A1 SBF1 PNPLA3 PLD2	1.07e-04	196	105	8	MM14591
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IRS4 NUP107 COPB1 PDHA1 SPTBN2 COPG2 CCT2 HUWE1 KRR1 XRCC5 TEX10 DDX27 XAB2 ZCCHC3 SBF1 MKI67 MACF1 PDS5A DYNC1H1	6.98e-12	653	132	19	22586326
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	LPCAT1 COPB1 PDHA1 COPG2 HUWE1 TRIP13 SRPRB SH3BP4 MACF1 CDC73 DYNC1H1 ARMC6	1.17e-10	235	132	12	28378594
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	NUP107 COPB1 PDHA1 HIP1R TSC1 CCT2 HUWE1 KRR1 XRCC5 TEX10 TRIP13 SRPRB DDX27 SBF1 CTR9 FHOD1 SHCBP1 MKI67 MACF1 PDS5A EIF3A DYNC1H1 ALDH7A1	1.60e-09	1353	132	23	29467282
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	PRPSAP1 LPCAT1 ACADVL APEX1 TSC1 CCT2 HUWE1 KRR1 XRCC5 PPWD1 TRIP13 SRPRB XAB2 RPS26P11 KRT75 JMJD6 CTR9 FHOD1 MACF1 PDS5A EIF3A CDC73 DYNC1H1	3.73e-09	1415	132	23	28515276
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	COPB1 ACADVL PDHA1 COPG2 CCT2 HUWE1 KRR1 XRCC5 TRIP13 SRPRB DDX27 XAB2 ZCCHC3 VPS52 ABCB10 JMJD6 CTR9 MKI67 EIF3A PSMD14 DYNC1H1 ARMC6	5.28e-09	1318	132	22	30463901
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	IRS4 NUP107 COPB1 ACADVL DSG2 SPTBN2 CCT2 HUWE1 XRCC5 TEX10 TRIP13 SRPRB DDX27 XAB2 RAB9A MKI67 MACF1 EIF3A DYNC1H1	1.24e-08	1024	132	19	24711643
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	IRS4 NUP107 COPB1 DSG2 PDHA1 CCT2 HUWE1 KRR1 XRCC5 TRIP13 SRPRB DDX27 RAB9A RPS26P11 CTR9 STARD9 MKI67 PDS5A EIF3A CDC73 PSMD14 DYNC1H1	2.13e-08	1425	132	22	30948266
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	IRS4 NUP107 COPB1 DSG2 COPG2 CCT2 HUWE1 XRCC5 TRIP13 CTR9 PDS5A EIF3A CDC73 PSMD14 DYNC1H1	2.27e-08	638	132	15	33239621
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DENND2A DPYSL3 COPB1 PDHA1 SPTBN2 TSC1 CCT2 PITPNM1 GPD1L SPTBN4 SLC44A1 SBF1 HECW2 VCAN MAST1 MACF1 EIF3A GNAQ CEP170B DYNC1H1 ALDH7A1 DNAH11	2.30e-08	1431	132	22	37142655
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	LPCAT1 IRS4 COPB1 PDHA1 COPG2 CCT2 XRCC5 TRIP13 SRPRB RAB9A RPS26P11 ABCB10 PSMD14 DYNC1H1	3.60e-08	565	132	14	33567341
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ABCA2 SPTBN2 XAB2 SPTBN4 PTPRN2 CTR9 MACF1 PLXNB3	3.83e-08	130	132	8	12421765
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ABCA2 COPB1 TNPO2 KRT83 SPTBN2 CCT2 ZNF227 HUWE1 DDX27 XAB2 SPTBN4 CTR9 MAST1 MACF1 TMEM131 GFPT2 ALDH5A1 DYNC1H1 PLXNB3 SOS2	8.85e-08	1285	132	20	35914814
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	PRPSAP1 COPB1 HIP1R APEX1 XRCC5 PARP14 SRPRB DDX27 ZCCHC3 SERPINE1 MACF1 EIF3A PSMD14 DYNC1H1 ALDH7A1	9.30e-08	711	132	15	33022573
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	IRS4 NUP107 COPB1 PDHA1 COPG2 HUWE1 XRCC5 TRIP13 EIF3A CDC73 PSMD14 ALDH5A1 DYNC1H1	1.39e-07	534	132	13	35032548
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DNAH3 TNPO2 SPTBN2 HUWE1 GIMAP7 XRCC5 PARP14 LGALSL PTPRN2 HECW2 CCDC87 PDS5A EIF3A DYNC1H1 PLXNB3	1.45e-07	736	132	15	29676528
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	IRS4 NUP107 COPB1 ACADVL TNPO2 COPG2 TEX10 XAB2 VPS52 ABCB10 CTR9 PDS5A DYNC1H1	2.39e-07	560	132	13	35241646
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	PRPSAP1 COPB1 ACADVL COPG2 CCT2 HUWE1 SRPRB KRT75 JMJD6 CTR9 EIF3A GFPT2 PSMD14 DYNC1H1	2.63e-07	665	132	14	30457570
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ZBTB33 NUP107 COPB1 DSG2 LRRK2 COPG2 CCT2 HUWE1 SRPRB SH3BP4 VPS52 MKI67 PDS5A PCDH7 DYNC1H1	2.89e-07	777	132	15	35844135
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DPYSL3 IRS4 NUP107 SPTBN2 COPG2 TSC1 CCT2 HUWE1 TEX10 DDX27 PTPRE SBF1 PTPRN2 CTR9 MKI67 PSMD14 PCDH7	5.16e-07	1049	132	17	27880917
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	PRPSAP1 NUP107 COPB1 DSG2 HIP1R HUWE1 TRIP13 SRPRB VPS52 ABCB10 PDS5A TMEM131 CDC73	5.83e-07	606	132	13	36538041
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	ZBTB33 NUP107 CCT2 HUWE1 XRCC5 TRIP13 XAB2 CTR9 PDS5A DYNC1H1	6.12e-07	332	132	10	32786267
Pubmed	ABCE1 is a highly conserved RNA silencing suppressor.	DSG2 PDHA1 APEX1 STARD9 MACF1 GNA11 GNAQ PSMD14	1.21e-06	204	132	8	25659154
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	COPB1 SPTBN2 XRCC5 XAB2 MKI67 DYNC1H1	1.28e-06	90	132	6	35654790
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	LPCAT1 DPYSL3 NUP107 DSG2 COPG2 CCT2 HUWE1 XRCC5 TIMMDC1 SRPRB GPD1L ABCB10 ZPR1 FHOD1 DYNC1H1	1.33e-06	878	132	15	37223481
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SPTBN2 PITPNM1 MACF1 AKAP11 GNA11 GNAQ PCDH7 CEP170B DYNC1H1	1.38e-06	281	132	9	28706196
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	IRS4 PDHA1 CCT2 HUWE1 XRCC5 TRIP13 SRPRB CTR9 MKI67 CDC73 DYNC1H1	1.69e-06	463	132	11	34901782
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	DPYSL3 IRS4 COPB1 TNPO2 SPTBN2 APEX1 COPG2 CCT2 HUWE1 XRCC5 TRIP13 MACF1 PDS5A EIF3A PSMD14 DYNC1H1 ALDH7A1	1.79e-06	1149	132	17	35446349
Pubmed	Human transcription factor protein interaction networks.	IRS4 ZBTB33 NUP107 COPB1 KRT74 TNPO2 CCT2 KRR1 XRCC5 TEX10 DDX27 ZCCHC3 MKI67 PDS5A EIF3A GFPT2 PSMD14 PCDH7 DYNC1H1	2.03e-06	1429	132	19	35140242
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PRPSAP1 IRS4 COPB1 TNPO2 SPTBN2 COPG2 CCT2 HUWE1 KRR1 XRCC5 TRIP13 SRPRB DDX27 SERPINE1 MKI67 PDS5A EIF3A PSMD14 DYNC1H1	2.27e-06	1440	132	19	30833792
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ABCA2 IRS4 COPB1 ACADVL APEX1 COPG2 CCT2 HUWE1 XRCC5 RPS26P11 MACF1 EIF3A PSMD14 DYNC1H1	2.57e-06	807	132	14	30575818
Pubmed	A human MAP kinase interactome.	WAS KIF26A SPTBN2 DDX27 SH3BP4 USF3 FHOD1 MACF1 EIF3A ARHGAP33 SOS2	2.69e-06	486	132	11	20936779
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	DPYSL3 IRS4 ZBTB33 NUP107 COPB1 DSG2 COPG2 TSC1 CCT2 XRCC5 XAB2 FHOD1 MKI67 MACF1 EIF3A	2.83e-06	934	132	15	33916271
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	LPCAT1 COPG2 TRIP13 VPS52 FHOD1 ARMC6	2.98e-06	104	132	6	31240132
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	LPCAT1 NUP107 COPB1 DSG2 COPG2 HUWE1 TEX10 TIMMDC1 TRIP13 SRPRB RNF43 VPS52 ABCB10 PDS5A DYNC1H1	3.14e-06	942	132	15	31073040
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	DNAH3 KIF26A HSPA12B STARD9 MKI67 MAST1 EIF3A DNAH11	3.25e-06	233	132	8	37704626
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	IMPG1 XRCC5 GRM7 PTPRE PTPRN2 VCAN ALDH5A1	4.32e-06	171	132	7	20201926
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	IRS4 COPB1 COPG2 CCT2 HUWE1 KRR1 XRCC5 DDX27 ZCCHC3 CTR9 QPRT PDS5A EIF3A CDC73 PSMD14	4.53e-06	971	132	15	33306668
Pubmed	Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.	IRS4 COPB1 HUWE1 MKI67 DYNC1H1	4.65e-06	64	132	5	22865885
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	NUP107 ACADVL HUWE1 KRR1 TEX10 DDX27 XAB2 ZCCHC3 MKI67	5.36e-06	332	132	9	25693804
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	LPCAT1 IRS4 COPB1 ACADVL COPG2 CCT2 HUWE1 XRCC5 ABCB10 EIF3A PSMD14 DYNC1H1	7.12e-06	647	132	12	26618866
Pubmed	Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase.	LPCAT1 IRS4 CCT2 SRPRB PSMD14	7.25e-06	70	132	5	21726808
Pubmed	The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.	COPB1 COPG2 HUWE1 DDX27	7.45e-06	33	132	4	26296893
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	IRS4 NUP107 HUWE1 XRCC5 TEX10 DDX27 SBF1 CTR9 MKI67 GFPT2	7.50e-06	440	132	10	34244565
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	ZBTB33 HUWE1 KRR1 XRCC5 TEX10 DDX27 ZCCHC3 MKI67 EIF3A	8.00e-06	349	132	9	25665578
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	COPB1 KRT74 COPG2 CCT2 KRR1 XRCC5 ZCCHC3 USF3 RPS26P11 KRT75 CTR9 MACF1 EIF3A CDC73 PSMD14 DYNC1H1	8.23e-06	1153	132	16	29845934
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	NUP107 DSG2 PDHA1 XRCC5 PPWD1 CTR9 MKI67 MACF1 GNA11 EIF3A CDC73 PLD2	8.69e-06	660	132	12	32780723
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	PRPSAP1 IRS4 SPTBN2 CCT2 HUWE1 KRR1 XRCC5 XAB2 ZCCHC3 EIF3A CDC73	8.80e-06	551	132	11	34728620
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	LPCAT1 IRS4 COPB1 DSG2 COPG2 CCT2 HUWE1 SRPRB RNF43 STARD9	8.94e-06	449	132	10	31732153
Pubmed	Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.	COPB1 PDHA1 COPG2 CCT2 XRCC5 EIF3A GNAQ ARMC6	9.29e-06	269	132	8	30442662
Pubmed	A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.	IRS4 NUP107 DSG2 PDHA1 APEX1 CCT2 HUWE1 XRCC5 RAB9A EIF3A PSMD14 DYNC1H1 ALDH7A1	9.93e-06	786	132	13	29128334
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PRPSAP1 DPYSL3 COPB1 PDHA1 APEX1 CCT2 HUWE1 XRCC5 TRIP13 JMJD6 CTR9 ZPR1 MACF1 EIF3A CDC73 PSMD14 DYNC1H1 ALDH7A1	1.03e-05	1455	132	18	22863883
Pubmed	Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.	RAB9B DENND2A RAB9A SBF1	1.19e-05	37	132	4	20937701
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	DNAH3 DPYSL3 ACADVL COPG2 TSC1 CCT2 XRCC5 SRPRB MKI67 EIF3A PSMD14 DYNC1H1 SOS2	1.24e-05	803	132	13	36517590
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NUP107 ACADVL DSG2 PDHA1 SPTBN2 XRCC5 HSPA12B TIMMDC1 SRPRB DDX27 SH3BP4 ABCB10 SBF1 CTR9 MACF1 AKAP11 TMEM131 PCDH7	1.38e-05	1487	132	18	33957083
Pubmed	The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.	GNA11 GNAQ	1.43e-05	2	132	2	28248732
Pubmed	Activation of Gq/11 in the mouse corpus luteum is required for parturition.	GNA11 GNAQ	1.43e-05	2	132	2	25495873
Pubmed	Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimens.	GNA11 GNAQ	1.43e-05	2	132	2	21945171
Pubmed	Ku antigen displays the AP lyase activity on a certain type of duplex DNA.	APEX1 XRCC5	1.43e-05	2	132	2	27129632
Pubmed	Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.	GNA11 GNAQ	1.43e-05	2	132	2	9175863
Pubmed	The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.	GNA11 GNAQ	1.43e-05	2	132	2	28083870
Pubmed	Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.	GNA11 GNAQ	1.43e-05	2	132	2	26843449
Pubmed	Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.	GNA11 GNAQ	1.43e-05	2	132	2	30890659
Pubmed	Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.	GNA11 GNAQ	1.43e-05	2	132	2	9607776
Pubmed	Reverse Phenotyping in Patients with Skin Capillary Malformations and Mosaic GNAQ or GNA11 Mutations Defines a Clinical Spectrum with Genotype-Phenotype Correlation.	GNA11 GNAQ	1.43e-05	2	132	2	31726051
Pubmed	G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region.	GNA11 GNAQ	1.43e-05	2	132	2	11438569
Pubmed	GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.	GNA11 GNAQ	1.43e-05	2	132	2	37802294
Pubmed	Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.	GNA11 GNAQ	1.43e-05	2	132	2	26628681
Pubmed	The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis.	GNA11 GNAQ	1.43e-05	2	132	2	17552882
Pubmed	Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.	GNA11 GNAQ	1.43e-05	2	132	2	31173078
Pubmed	Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.	GNA11 GNAQ	1.43e-05	2	132	2	29209985
Pubmed	Rab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus.	RAB9B RAB9A	1.43e-05	2	132	2	16140752
Pubmed	Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior.	GNA11 GNAQ	1.43e-05	2	132	2	15175381
Pubmed	Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.	GNA11 GNAQ	1.43e-05	2	132	2	25280020
Pubmed	GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.	GNA11 GNAQ	1.43e-05	2	132	2	27498141
Pubmed	Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.	GNA11 GNAQ	1.43e-05	2	132	2	28982892
Pubmed	Mutations in GNA11 in uveal melanoma.	GNA11 GNAQ	1.43e-05	2	132	2	21083380
Pubmed	GNAQ and GNA11 mutations in uveal melanoma.	GNA11 GNAQ	1.43e-05	2	132	2	25304237
Pubmed	Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.	GNA11 GNAQ	1.43e-05	2	132	2	28301547
Pubmed	Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.	GNA11 GNAQ	1.43e-05	2	132	2	16847339
Pubmed	Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.	GNA11 GNAQ	1.43e-05	2	132	2	29570931
Pubmed	Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice.	GNA11 GNAQ	1.43e-05	2	132	2	10818132
Pubmed	Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.	GNA11 GNAQ	1.43e-05	2	132	2	26272756
Pubmed	NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.	GNA11 GNAQ	1.43e-05	2	132	2	31461351
Pubmed	Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.	GNA11 GNAQ	1.43e-05	2	132	2	23634288
Pubmed	Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.	GNA11 GNAQ	1.43e-05	2	132	2	26368812
Pubmed	Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.	GNA11 GNAQ	1.43e-05	2	132	2	17482476
Pubmed	Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.	GNA11 GNAQ	1.43e-05	2	132	2	24141786
Pubmed	Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends.	APEX1 XRCC5	1.43e-05	2	132	2	22362780
Pubmed	Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation.	GNA11 GNAQ	1.43e-05	2	132	2	37102682
Pubmed	Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways.	GNA11 GNAQ	1.43e-05	2	132	2	7492305
Pubmed	Reduced trabecular bone mass and strength in mice overexpressing Gα11 protein in cells of the osteoblast lineage.	GNA11 GNAQ	1.43e-05	2	132	2	24308950
Pubmed	Gαq and Gα11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes.	GNA11 GNAQ	1.43e-05	2	132	2	22562663
Pubmed	Functional specificity of G alpha q and G alpha 11 in the cholinergic and glutamatergic modulation of potassium currents and excitability in hippocampal neurons.	GNA11 GNAQ	1.43e-05	2	132	2	11826096
Pubmed	Blue nevi and variants: an update.	GNA11 GNAQ	1.43e-05	2	132	2	21366456
Pubmed	In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.	GNA11 GNAQ	1.43e-05	2	132	2	35580369
Pubmed	Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion.	ABCA2 ABCB10	1.43e-05	2	132	2	21788586
Pubmed	Papillary Hemangioma Harbors Somatic GNA11 and GNAQ Mutations.	GNA11 GNAQ	1.43e-05	2	132	2	37750536
Pubmed	Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis.	GNA11 GNAQ	1.43e-05	2	132	2	26778290
Pubmed	Implication between Genetic Variants from APOA5 and ZPR1 and NAFLD Severity in Patients with Hypertriglyceridemia.	APOA5 ZPR1	1.43e-05	2	132	2	33567543
Pubmed	Skeletal Muscle-Specific Activation of Gq Signaling Maintains Glucose Homeostasis.	GNA11 GNAQ	1.43e-05	2	132	2	30936140
Interaction	TES interactions	LPCAT1 COPB1 PDHA1 APEX1 COPG2 HUWE1 TRIP13 SRPRB RNF43 SH3BP4 ZPR1 MACF1 CDC73 DYNC1H1 ARMC6	3.99e-09	332	130	15	int:TES
Interaction	YWHAZ interactions	IRS4 ZBTB33 PDE6C NUP107 COPB1 DSG2 SPTBN2 LRRK2 HIP1R TSC1 HUWE1 KRR1 SH3BP4 SBF1 STARD9 FHOD1 SHCBP1 MAST1 MACF1 AKAP11 EIF3A CDC73 PSMD14 PCDH7 CEP170B DYNC1H1	2.69e-07	1319	130	26	int:YWHAZ
Interaction	SIRT7 interactions	IRS4 NUP107 COPB1 PDHA1 SPTBN2 COPG2 CCT2 HUWE1 KRR1 XRCC5 TEX10 DDX27 XAB2 ZCCHC3 SBF1 MKI67 MACF1 PDS5A DYNC1H1	3.07e-07	744	130	19	int:SIRT7
Interaction	CDC42 interactions	PRPSAP1 LPCAT1 IRS4 PDE6C WAS ACADVL DSG2 SPTBN2 LRRK2 APEX1 HUWE1 TEX10 SRPRB SH3BP4 VPS52 RAB9A SBF1 FHOD1 MKI67 GNA11 TMEM131 PCDH7 RHOF ARHGAP33 ARMC6	1.04e-06	1323	130	25	int:CDC42
Interaction	CCDC8 interactions	IRS4 COPB1 ACADVL DSG2 SPTBN2 CCT2 HUWE1 XRCC5 TRIP13 SRPRB RAB9A PTPRN2 MKI67 MACF1 EIF3A RHOF DYNC1H1	1.12e-06	656	130	17	int:CCDC8
Interaction	BSG interactions	CLUAP1 DSG2 PDHA1 TNPO2 APEX1 HUWE1 HSPA12B TRIP13 GPD1L SPTBN4 VPS52 RAB9A PDS5A PLD2 RHOF ALDH7A1	3.14e-06	631	130	16	int:BSG
Interaction	STIP1 interactions	IRS4 NUP107 COPB1 DSG2 LRRK2 COPG2 CCT2 HUWE1 XRCC5 TRIP13 RNF43 SBF1 CTR9 PDS5A EIF3A CDC73 PSMD14 PCDH7 RHOF DYNC1H1	6.91e-06	1006	130	20	int:STIP1
Interaction	YWHAB interactions	IRS4 PDE6C NUP107 DSG2 LRRK2 TSC1 KRR1 XRCC5 PPWD1 RNF43 SH3BP4 CTR9 STARD9 SHCBP1 MAST1 MACF1 AKAP11 CDC73 CEP170B DYNC1H1	7.76e-06	1014	130	20	int:YWHAB
Interaction	AGAP2 interactions	TRO SPTBN2 PITPNM1 MACF1 GNA11 GNAQ PCDH7 CEP170B DYNC1H1	9.05e-06	210	130	9	int:AGAP2
Interaction	KIF23 interactions	LPCAT1 COPB1 ACADVL DSG2 TNPO2 APEX1 COPG2 HUWE1 KRR1 XRCC5 TRIP13 SRPRB DDX27 RAB9A RPS26P11 SHCBP1 MKI67 MACF1 GNA11 DYNC1H1	9.91e-06	1031	130	20	int:KIF23
Interaction	XPOT interactions	NUP107 APEX1 HUWE1 RAB9A PTPRE KRT75 PTPRN2 RHOF ARMC6	1.31e-05	220	130	9	int:XPOT
Interaction	RHOJ interactions	LPCAT1 IRS4 WAS DSG2 SPTBN2 SRPRB DDX27 SH3BP4 RAB9A SBF1 FHOD1 MACF1 GNA11 PCDH7 ARHGAP33	1.46e-05	633	130	15	int:RHOJ
Interaction	RAC1 interactions	PRPSAP1 LPCAT1 IRS4 WAS DSG2 SPTBN2 LRRK2 TSC1 HUWE1 SRPRB SH3BP4 VPS52 RAB9A ABCB10 SBF1 FHOD1 MACF1 GNA11 PCDH7 ARHGAP33	1.55e-05	1063	130	20	int:RAC1
Interaction	CIT interactions	AMPD3 NUP107 COPB1 DSG2 PDHA1 TNPO2 SPTBN2 LRRK2 CCT2 XRCC5 TEX10 PPWD1 TRIP13 XAB2 SPTBN4 RPS26P11 CTR9 HECW2 MKI67 MACF1 PDS5A EIF3A CDC73 DYNC1H1	1.68e-05	1450	130	24	int:CIT
Interaction	ABCE1 interactions	DSG2 PDHA1 APEX1 XRCC5 DDX27 STARD9 MACF1 GNA11 EIF3A GNAQ PSMD14 RHOF	2.33e-05	431	130	12	int:ABCE1
Interaction	KCTD13 interactions	DENND2A DPYSL3 COPB1 PDHA1 SPTBN2 TSC1 CCT2 PITPNM1 GPD1L SPTBN4 SLC44A1 SBF1 HECW2 VCAN MAST1 MACF1 EIF3A GNAQ GFPT2 CEP170B DYNC1H1 ALDH7A1 DNAH11	2.72e-05	1394	130	23	int:KCTD13
Interaction	SINHCAF interactions	IRS4 COPB1 ACADVL HUWE1 HECW2 MKI67 DYNC1H1	2.76e-05	135	130	7	int:SINHCAF
Interaction	SUMO2 interactions	ZBTB33 NUP107 LRRK2 CCT2 HUWE1 XRCC5 TEX10 TRIP13 RNF43 XAB2 CTR9 MKI67 PDS5A DYNC1H1	2.87e-05	591	130	14	int:SUMO2
Interaction	RHOF interactions	LPCAT1 IRS4 DSG2 SPTBN2 HIP1R TEX10 SRPRB SH3BP4 VPS52 RAB9A SBF1 MACF1 PCDH7 RHOF ARMC6	2.96e-05	673	130	15	int:RHOF
Interaction	SPRTN interactions	LPCAT1 IRS4 COPB1 PDHA1 COPG2 CCT2 HUWE1 TRIP13 SRPRB RAB9A RPS26P11 ABCB10 PSMD14 DYNC1H1	3.15e-05	596	130	14	int:SPRTN
Interaction	CDC5L interactions	NUP107 COPB1 HIP1R COPG2 CCT2 HUWE1 KRR1 TEX10 PPWD1 TRIP13 XAB2 VPS52 FHOD1 MAST1 MACF1 CDC73 DYNC1H1	3.61e-05	855	130	17	int:CDC5L
Interaction	SERBP1 interactions	LPCAT1 DPYSL3 NUP107 DSG2 PDHA1 TNPO2 COPG2 CCT2 HUWE1 KRR1 XRCC5 TEX10 TIMMDC1 SRPRB ZCCHC3 GPD1L HARS2 ABCB10 ZPR1 FHOD1 EIF3A PSMD14 DYNC1H1	4.14e-05	1432	130	23	int:SERBP1
Interaction	DNAJA1 interactions	CLUAP1 PDHA1 TNPO2 LRRK2 TSC1 CCT2 HUWE1 RNF43 JMJD6 CDC73 PLD2 PSMD14 PCDH7	4.17e-05	533	130	13	int:DNAJA1
Interaction	YWHAG interactions	DPYSL3 IRS4 ZBTB33 COPB1 DSG2 LRRK2 TSC1 CCT2 HUWE1 KRR1 DDX27 SH3BP4 SBF1 STARD9 SHCBP1 MACF1 AKAP11 PCDH7 CEP170B DYNC1H1 ALDH7A1	4.82e-05	1248	130	21	int:YWHAG
Interaction	YWHAE interactions	PRPSAP1 IRS4 ZBTB33 LRRK2 TSC1 HUWE1 RNF43 SH3BP4 SBF1 ZPR1 SHCBP1 MAST1 MACF1 AKAP11 EIF3A CDC73 PCDH7 CEP170B DYNC1H1 ALDH7A1 ARHGAP33	5.29e-05	1256	130	21	int:YWHAE
Interaction	PRC1 interactions	NUP107 COPB1 DSG2 PDHA1 SPTBN2 TSC1 CCT2 KRR1 XRCC5 TRIP13 DDX27 SPTBN4 USF3 RPS26P11 MKI67 PDS5A DYNC1H1 ARHGAP33	5.36e-05	973	130	18	int:PRC1
Interaction	NUDCD1 interactions	COPB1 PDHA1 COPG2 HECW2 DYNC1H1	5.38e-05	63	130	5	int:NUDCD1
Interaction	CLEC16A interactions	PRPSAP1 NUP107 COPB1 DSG2 HIP1R APEX1 HUWE1 TRIP13 SRPRB VPS52 ABCB10 PDS5A TMEM131 CDC73	5.63e-05	629	130	14	int:CLEC16A
Interaction	WDR91 interactions	APEX1 CCT2 HUWE1 RAB9A	6.60e-05	34	130	4	int:WDR91
Interaction	WDR5 interactions	PRPSAP1 CLUAP1 NUP107 COPB1 HIP1R APEX1 CCT2 XRCC5 PARP14 SRPRB DDX27 ZCCHC3 SBF1 SERPINE1 MACF1 EIF3A PSMD14 DYNC1H1 ALDH7A1	8.26e-05	1101	130	19	int:WDR5
Interaction	NR2C2 interactions	COPB1 ACADVL PDHA1 COPG2 CCT2 HUWE1 KRR1 XRCC5 TRIP13 SRPRB DDX27 XAB2 ZCCHC3 VPS52 ABCB10 JMJD6 CTR9 MKI67 EIF3A PSMD14 DYNC1H1 ARMC6	8.88e-05	1403	130	22	int:NR2C2
Interaction	YWHAQ interactions	IRS4 PDE6C NUP107 DSG2 LRRK2 TSC1 KRR1 RNF43 SH3BP4 SBF1 STARD9 SHCBP1 MACF1 AKAP11 CDC73 PCDH7 CEP170B DYNC1H1 ALDH7A1	1.01e-04	1118	130	19	int:YWHAQ
Interaction	SRP9 interactions	CLUAP1 LRRK2 HUWE1 SRPRB JMJD6 CTR9 VCAN MAST1 EIF3A CDC73 RHOF	1.03e-04	427	130	11	int:SRP9
Interaction	RHOC interactions	PRPSAP1 LPCAT1 DSG2 SPTBN2 APEX1 SRPRB SH3BP4 RAB9A SBF1 MACF1 GNA11 TMEM131 PCDH7	1.05e-04	584	130	13	int:RHOC
Interaction	PCK1 interactions	LPCAT1 CLUAP1 IRS4 CCT2 SRPRB PSMD14	1.23e-04	119	130	6	int:PCK1
Interaction	RHOQ interactions	IRS4 WAS COPB1 DSG2 SPTBN2 SH3BP4 RAB9A SBF1 GNA11 PCDH7 RHOF	1.40e-04	442	130	11	int:RHOQ
Interaction	WDR48 interactions	ZBTB33 TSC1 CCT2 HUWE1 JMJD6 MKI67 EIF3A	1.53e-04	177	130	7	int:WDR48
Interaction	CANX interactions	DNAH3 ABCA2 NUP107 COPB1 ACADVL DSG2 PDHA1 LRRK2 COPG2 HUWE1 SRPRB RNF43 EDEM3 SLC44A1 PTPRE JMJD6 EDEM2 CDC73 DNAH9 RHOF	1.66e-04	1261	130	20	int:CANX
Interaction	SPRYD7 interactions	APEX1 TRIP13 HARS2 SBF1	1.84e-04	44	130	4	int:SPRYD7
Interaction	C9orf78 interactions	IRS4 NUP107 COPB1 ACADVL TNPO2 COPG2 TEX10 XAB2 VPS52 ABCB10 CTR9 PDS5A DYNC1H1	1.89e-04	620	130	13	int:C9orf78
Interaction	BIN1 interactions	IRS4 HUWE1 XRCC5 CDC73 PLD2 SOS2	1.91e-04	129	130	6	int:BIN1
Interaction	SIRT6 interactions	IRS4 NUP107 APEX1 HUWE1 XRCC5 TEX10 DDX27 SBF1 CTR9 MKI67 PDS5A GFPT2 PCDH7	2.14e-04	628	130	13	int:SIRT6
Interaction	NT5E interactions	TNPO2 SLC44A1 RAB9A PDS5A PCDH7	2.24e-04	85	130	5	int:NT5E
Interaction	CCT8 interactions	PDHA1 LRRK2 TSC1 CCT2 HUWE1 MACF1 EIF3A CDC73 GFPT2 PSMD14 PCDH7 ARMC6	2.35e-04	550	130	12	int:CCT8
Interaction	BOP1 interactions	SPTBN2 HIP1R HUWE1 KRR1 DDX27 JMJD6 MAST1	2.44e-04	191	130	7	int:BOP1
Interaction	USP53 interactions	COPB1 SPTBN2 XRCC5 XAB2 MKI67 DYNC1H1	2.75e-04	138	130	6	int:USP53
Interaction	RNF126 interactions	IRS4 COPB1 HUWE1 XRCC5 RNF43 EIF3A	2.75e-04	138	130	6	int:RNF126
Interaction	RNF123 interactions	DNAH3 TNPO2 SPTBN2 HUWE1 GIMAP7 XRCC5 PARP14 LGALSL PTPRN2 HECW2 CCDC87 PDS5A EIF3A DYNC1H1 PLXNB3	2.79e-04	824	130	15	int:RNF123
Interaction	TUBB interactions	DPYSL3 PDHA1 TNPO2 LRRK2 CCT2 HUWE1 RNF43 DHDH GFPT2 PLD2 PSMD14 PCDH7 DYNC1H1 ARMC6	2.86e-04	735	130	14	int:TUBB
Interaction	TRMT1 interactions	ACADVL PDHA1 APEX1 XRCC5 DDX27 AKAP11	2.97e-04	140	130	6	int:TRMT1
Interaction	PSMB3 interactions	LRRK2 OSER1 TOGARAM1 HUWE1 HECW2 PSMD14 DYNC1H1	3.03e-04	198	130	7	int:PSMB3
Interaction	LINC01554 interactions	ACADVL APEX1 CCT2 XRCC5 EIF3A DYNC1H1	3.21e-04	142	130	6	int:LINC01554
Interaction	TBC1D10B interactions	APEX1 HUWE1 EIF3A RHOF DYNC1H1	3.25e-04	92	130	5	int:TBC1D10B
Interaction	USP14 interactions	IRS4 DSG2 SPTBN2 CCT2 XRCC5 TRIP13 SRPRB MACF1 GNA11 PSMD14 DYNC1H1	3.33e-04	489	130	11	int:USP14
Interaction	BIRC3 interactions	IRS4 NUP107 COPB1 DSG2 PDHA1 CCT2 HUWE1 KRR1 XRCC5 TRIP13 SRPRB RAB9A CTR9 STARD9 MKI67 PDS5A EIF3A CDC73 PSMD14 DYNC1H1	3.47e-04	1334	130	20	int:BIRC3
Interaction	ATP1A1 interactions	CACNA1D NUP107 PDHA1 CCT2 HUWE1 XRCC5 DDX27 RAB9A EIF3A RHOF DYNC1H1 ALDH7A1	3.52e-04	575	130	12	int:ATP1A1
GeneFamily	Dyneins, axonemal	DNAH3 DNAH9 DNAH11	6.73e-05	17	86	3	536
GeneFamily	Keratins, type II	KRT74 KRT83 KRT75	2.80e-04	27	86	3	609
GeneFamily	Tetratricopeptide repeat domain containing\|Paf1/RNA polymerase II complex	CTR9 CDC73	3.31e-04	6	86	2	1029
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN2 SPTBN4	4.62e-04	7	86	2	1113
Coexpression	MARTINEZ_RB1_AND_TP53_TARGETS_DN	LPCAT1 DPYSL3 ABCA2 TRO KRT83 SPTBN2 CCT2 CACFD1 HUWE1 TIMMDC1 TRIP13 SLC44A1 PTPRE KRT75 MKI67 PDS5A PLXNB3	1.24e-08	610	132	17	M3854
Coexpression	MARTINEZ_RB1_AND_TP53_TARGETS_DN	LPCAT1 DPYSL3 ABCA2 TRO KRT83 SPTBN2 CCT2 CACFD1 HUWE1 TIMMDC1 TRIP13 SLC44A1 PTPRE KRT75 MKI67 PDS5A PLXNB3	3.14e-08	650	132	17	MM1042
Coexpression	MARTINEZ_TP53_TARGETS_DN	LPCAT1 DPYSL3 ABCA2 TRO KRT83 SPTBN2 CCT2 CACFD1 HUWE1 SLC44A1 PTPRE KRT75 MKI67 PDS5A PLXNB3	5.21e-07	615	132	15	M8673
Coexpression	MITSIADES_RESPONSE_TO_APLIDIN_DN	LPCAT1 TRIP13 EDEM3 SHCBP1 MKI67 MACF1 PDS5A AKAP11 EIF3A ALDH5A1	5.87e-07	250	132	10	M11318
Coexpression	MARTINEZ_TP53_TARGETS_DN	LPCAT1 DPYSL3 ABCA2 TRO KRT83 SPTBN2 CCT2 CACFD1 HUWE1 SLC44A1 PTPRE KRT75 MKI67 PDS5A PLXNB3	1.23e-06	659	132	15	MM1040
Coexpression	BENPORATH_SOX2_TARGETS	PRPSAP1 DPYSL3 COPB1 KIF26A APEX1 HUWE1 XAB2 ZCCHC3 VPS52 SLC44A1 VCAN MAST1 ALDH7A1 ARMC6	2.10e-05	734	132	14	M3835
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	ZBTB33 COPB1 DSG2 TSC1 CCT2 XRCC5 TEX10 SRPRB DDX27 SH3BP4 GPD1L EDEM2 MACF1 TMEM131 PSMD14 ALDH5A1 DYNC1H1 SOS2	3.95e-05	1215	132	18	M41122
Coexpression	GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN	RAB9B DENND2A WAS TRO PARP14 PTPRE C2	6.92e-05	199	132	7	M7341
Coexpression	GSE39556_CD8A_DC_VS_NK_CELL_UP	PRPSAP1 TRIP13 GUCY1A1 MACF1 PDS5A GNAQ ALDH7A1	7.15e-05	200	132	7	M9406
Coexpression	GSE42724_B1_BCELL_VS_PLASMABLAST_DN	ZBTB33 PDHA1 CBFA2T2 AKAP11 EIF3A PLD2 CEP170B	7.15e-05	200	132	7	M9789
Coexpression	DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN	PRPSAP1 LPCAT1 ABCA2 SPTBN2 SBF1 VCAN MKI67 PCDH7	8.15e-05	276	132	8	M3063
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NAALADL1 TRO TRIP13 GUCY1A1 MKI67 CYP2U1 PCDH7	9.00e-07	174	132	7	41eb0a214a8b4015a26311f77061c8147144f0e7
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPYSL3 HSPA12B SH3BP4 STARD9 HECW2 SERPINE1 TMEM26	1.62e-06	190	132	7	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	CACNA1D DENND2A DPYSL3 VCAN SERPINE1 GFPT2 PCDH7	1.62e-06	190	132	7	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPYSL3 HSPA12B SH3BP4 STARD9 HECW2 SERPINE1 TMEM26	1.68e-06	191	132	7	f229abf69a1217194f74b0502486907e07dba989
ToppCell	ASK440-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	LPCAT1 TCIM LRRK2 LGALSL GUCY1A1 QPRT C2	2.06e-06	197	132	7	08d5bbeb77a4152af1c783bc958afcae24667767
ToppCell	18-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	SLC44A1 GUCY1A1 FHOD1 VCAN SHCBP1 MKI67 MACF1	2.20e-06	199	132	7	7ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SPTBN2 CCT2 TRIP13 RNF43 ZPR1 SHCBP1 PSMD14	2.20e-06	199	132	7	cdcdef1d95a8e476de016b1e11ee010438834be0
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRIP13 RAB9A DHDH LGALSL SERPINE1 GFPT2	4.93e-06	146	132	6	86cddd0e7f954547b7ffdccb0329cd5c4b725ac1
ToppCell	Int-URO-Myeloid-tDC\|Int-URO / Disease, Lineage and Cell Type	APEX1 HSPA12B DDX27 XAB2 SH3BP4 ALDH7A1	9.93e-06	165	132	6	9803c3db6cdcf925bea7d9c382bf4fd05acf3509
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	APEX1 SHCBP1 KCNJ14 MKI67 MAST1 ARHGAP33	1.03e-05	166	132	6	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPYSL3 TCIM HSPA12B HECW2 SERPINE1 TMEM26	1.73e-05	182	132	6	a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RAB9B SPTBN2 SPTBN4 PTPRN2 MAST1 RHOF	1.96e-05	186	132	6	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 TEX10 TRIP13 VCAN SHCBP1 MKI67	2.02e-05	187	132	6	a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 TEX10 TRIP13 VCAN SHCBP1 MKI67	2.02e-05	187	132	6	38ee33295a21db4aae5ba085df033db9693e41c6
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 TEX10 TRIP13 VCAN SHCBP1 MKI67	2.02e-05	187	132	6	dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD3 LPCAT1 DPYSL3 RNF43 VCAN GFPT2	2.08e-05	188	132	6	7471c194276161422326647f09022e94f3d1640c
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD3 LPCAT1 DPYSL3 RNF43 VCAN GFPT2	2.08e-05	188	132	6	053c251d3ddbeb866f34565aefca4535517b4387
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D DENND2A VCAN SERPINE1 GFPT2 PCDH7	2.21e-05	190	132	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	CACNA1D TCIM SLC44A1 GUCY1A1 MACF1 L3MBTL4	2.21e-05	190	132	6	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RAB9B SPTBN2 PTPRN2 MAST1 RHOF CEP170B	2.27e-05	191	132	6	5d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell	Entopeduncular-Neuronal-Inhibitory\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RAB9B SPTBN2 PTPRN2 MAST1 RHOF CEP170B	2.27e-05	191	132	6	73dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RAB9B SPTBN2 SPTBN4 PTPRN2 MAST1 RHOF	2.34e-05	192	132	6	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRO LGALSL GUCY1A1 SERPINE1 TMEM26 PCDH7	2.41e-05	193	132	6	469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ZBTB33 HUWE1 USF3 CTR9 PDS5A DYNC1H1	2.41e-05	193	132	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	DENND2A DPYSL3 VCAN SERPINE1 GFPT2 PCDH7	2.48e-05	194	132	6	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CACNA1D TCIM GUCY1A1 VCAN MACF1 PCDH7	2.48e-05	194	132	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SPTBN4 PTPRN2 MAST1 AKAP11 RHOF CEP170B	2.48e-05	194	132	6	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRPSAP1 DPYSL3 TCIM GIMAP7 HSPA12B HECW2	2.55e-05	195	132	6	8ab45ab94c722c4aef0229ee1121cd744bf659dd
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CACNA1D TCIM GUCY1A1 VCAN MACF1 PCDH7	2.55e-05	195	132	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1D DENND2A DPYSL3 MACF1 GFPT2 PCDH7	2.63e-05	196	132	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	ASK452-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	LPCAT1 TCIM LRRK2 VCAN SERPINE1 C2	2.70e-05	197	132	6	e92757e988888347c74286cc42c262b03159b0b9
ToppCell	ASK428-Epithelial-Type_2\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	LPCAT1 TCIM LRRK2 LGALSL GUCY1A1 C2	2.78e-05	198	132	6	ec0d1801363adb70c6a26655b79d12b438c7417d
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1D DENND2A DPYSL3 MACF1 GFPT2 PCDH7	2.78e-05	198	132	6	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRO HIP1R GRM7 VCAN PCDH7 PLXNB3	2.86e-05	199	132	6	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	normal_Lung-Endothelial_cells-Tip-like_ECs\|normal_Lung / Location, Cell class and cell subclass	PRPSAP1 DPYSL3 TCIM GIMAP7 HSPA12B HECW2	2.86e-05	199	132	6	1ae0b47fade7b1cd74c0faabcf4f12f56f62264e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRO LRRK2 HIP1R GRM7 VCAN PCDH7	2.86e-05	199	132	6	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRO HIP1R GRM7 VCAN PCDH7 PLXNB3	2.86e-05	199	132	6	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D LRRK2 GRM7 PTPRE VCAN PCDH7	2.94e-05	200	132	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D LRRK2 GRM7 PTPRE VCAN PCDH7	2.94e-05	200	132	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D LRRK2 GRM7 PTPRE VCAN PCDH7	2.94e-05	200	132	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRO HIP1R GRM7 VCAN PCDH7 PLXNB3	2.94e-05	200	132	6	ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1D DENND2A DPYSL3 VCAN GFPT2 PCDH7	2.94e-05	200	132	6	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Sepsis-Int-URO-Myeloid-tDC\|Int-URO / Disease, condition lineage and cell class	APEX1 DDX27 XAB2 SH3BP4 PTPRE ALDH7A1	2.94e-05	200	132	6	f5d0497a72da21cad24e0ef51c3dc4d024dbf294
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D LRRK2 GRM7 PTPRE VCAN PCDH7	2.94e-05	200	132	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1D DENND2A DPYSL3 VCAN GFPT2 PCDH7	2.94e-05	200	132	6	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D LRRK2 GRM7 PTPRE VCAN PCDH7	2.94e-05	200	132	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D LRRK2 GRM7 PTPRE VCAN PCDH7	2.94e-05	200	132	6	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT75 GUCY1A1 PNPLA3 PCDH7 ARMC6	9.02e-05	152	132	5	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT75 GUCY1A1 PNPLA3 PCDH7 ARMC6	9.02e-05	152	132	5	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 VCAN MKI67 C2 TMEM26	9.31e-05	153	132	5	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	COVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	1.08e-04	158	132	5	0d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LPCAT1 TCIM LRRK2 GPD1L C2	1.29e-04	164	132	5	beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	DSG2 HMCN2 VCAN SERPINE1 PCDH7	1.29e-04	164	132	5	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LPCAT1 TCIM LRRK2 GPD1L C2	1.29e-04	164	132	5	d005cfd821b87548b075120bffe65a0be9860463
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_1\|COVID-19_Mild / Disease condition and Cell class	REX1BD CYP2B6 USF3 ZPR1 VCAN	1.33e-04	165	132	5	ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	DPYSL3 HSPA12B STARD9 HECW2 SERPINE1	1.40e-04	167	132	5	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	DPYSL3 GRM7 HMCN2 SERPINE1 PCDH7	1.40e-04	167	132	5	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK2 VCAN PDS5A CYP2U1 DNAH11	1.44e-04	168	132	5	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 KIF26A CMPK2 HSPA12B HMCN2	1.48e-04	169	132	5	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 CLUAP1 GRM7 DNAH9 DNAH11	1.48e-04	169	132	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	343B-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	AMPD3 DSG2 TCIM PTPRE SERPINE1	1.61e-04	172	132	5	eb199c279fe8a2551121db37e9556893197d33ff
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GIMAP7 PITPNM1 QPRT SHCBP1 MKI67	1.61e-04	172	132	5	dd9ba79e1542fe9fa2c319077d83dd3fc0158f46
ToppCell	343B-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	AMPD3 DSG2 TCIM PTPRE SERPINE1	1.61e-04	172	132	5	709c6b77a7a52b873eefb6caca28a41291d384af
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIF26A COPG2 SHCBP1 MKI67 ARHGAP33	1.65e-04	173	132	5	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIF26A COPG2 SHCBP1 MKI67 ARHGAP33	1.65e-04	173	132	5	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DSG2 LRRK2 RNF43 GPD1L LGALSL	1.84e-04	177	132	5	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DSG2 LRRK2 RNF43 GPD1L LGALSL	1.84e-04	177	132	5	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	COVID-19_Mild-Hematopoietic_SC-HSPC\|COVID-19_Mild / Disease group, lineage and cell class	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	1.94e-04	179	132	5	19fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	1.94e-04	179	132	5	4bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WAS TDRD9 GIMAP7 PTPRE VCAN	1.94e-04	179	132	5	61dbfc1b9b0344c06a68142c181cd62993556a67
ToppCell	PBMC-Mild-Hematopoietic-HSPC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	1.94e-04	179	132	5	2f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	1.94e-04	179	132	5	3e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCell	COVID-19_Mild-Hematopoietic_SC\|COVID-19_Mild / Disease group, lineage and cell class	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	1.94e-04	179	132	5	50a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	2.04e-04	181	132	5	e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALADL1 SERPINE1 MKI67 C2 GFPT2	2.04e-04	181	132	5	c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	2.04e-04	181	132	5	54a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCell	PBMC-Mild-Hematopoietic-HSPC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	DPYSL3 DSG2 TRO SPTBN2 GUCY1A1	2.04e-04	181	132	5	5b84625b1d3737708001b64f6da9360330d39a27
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A DNAH3 DAO GRM7 PNPLA3	2.04e-04	181	132	5	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	SLC44A1 VCAN SHCBP1 MKI67 GNAQ	2.04e-04	181	132	5	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DENND2A HSPA12B HMCN2 MTCP1	2.07e-04	98	132	4	a74fb790c135bd0d0033df3aca7b789d8b25e361
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DENND2A HSPA12B HMCN2 MTCP1	2.07e-04	98	132	4	cb0941481aef9068d7dbce0d1b6cf125f482a98d
ToppCell	CD8+_Memory_T_cell-RSV-2\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	CATSPER1 SHCBP1 MKI67 PNPLA3 GNAQ	2.09e-04	182	132	5	f5f17a80552f0ad05ed1a2529a04ee55deb1e130
ToppCell	healthy_donor-Myeloid-Monocytic-SC_&_Eosinophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	DPYSL3 DSG2 SPTBN2 GUCY1A1 GNAQ	2.09e-04	182	132	5	6bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTBN4 SHCBP1 MKI67 RHOF ARHGAP33	2.20e-04	184	132	5	bba0138c8f7e3645a688b9a4d12f6f2134ee2c08
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PLB1 WAS LRRK2 PTPRE RHOF	2.20e-04	184	132	5	315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTBN4 SHCBP1 MKI67 RHOF ARHGAP33	2.20e-04	184	132	5	eaef1dcde60ba14e2c7fd699d01c225487256d82
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTBN4 SHCBP1 MKI67 RHOF ARHGAP33	2.20e-04	184	132	5	fa73738350654066d7f9ebf78359e20ee6cbdd98
ToppCell	AT2_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	LPCAT1 CYP2B6 TCIM LRRK2 LGALSL	2.26e-04	185	132	5	3b3268e3f99121124e33086cac88479808d31630
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1D DENND2A DPYSL3 HMCN2 GFPT2	2.26e-04	185	132	5	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LPCAT1 TCIM LRRK2 LGALSL C2	2.26e-04	185	132	5	7460387f48f33674330bd53b759681b264228f5a
ToppCell	Mild-NK\|World / Disease group and Cell class	CMPK2 RANBP17 CATSPER1 GUCY1A1 L3MBTL4	2.26e-04	185	132	5	0565b7c464e1a09e596f5a0b363d2dc9b55c3c50
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RAB9B PTPRN2 MAST1 GNAQ RHOF	2.32e-04	186	132	5	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LPCAT1 TCIM LRRK2 GUCY1A1 C2	2.37e-04	187	132	5	7c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCell	control-Lymphocytic-Plasmablast\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TRIP13 SRPRB SLC44A1 SHCBP1 MKI67	2.37e-04	187	132	5	94a44b31ce9fe6fb4758769018fb746e93c8f043
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TCIM HSPA12B MTCP1 HECW2 SERPINE1	2.37e-04	187	132	5	97b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	HUWE1 PARP14 MACF1 TMEM131 DYNC1H1	2.43e-04	188	132	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF26A TCIM HSPA12B HECW2 SERPINE1	2.43e-04	188	132	5	0026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CACNA1D GUCY1A1 FHOD1 VCAN MACF1	2.43e-04	188	132	5	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	DPYSL3 DDX27 RNF43 CBFA2T2 VCAN	2.43e-04	188	132	5	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RAB9B PTPRN2 MAST1 GNAQ RHOF	2.43e-04	188	132	5	b73e8a40393c3f656e2fcfe395a761b1f985c254
Drug	3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; HL60; HT_HG-U133A	DPYSL3 ABCA2 TNPO2 HIP1R XAB2 SERPINE1 GNA11 ALDH5A1 ARHGAP33 ARMC6	2.23e-07	196	132	10	2941_UP
Disease	Uveal melanoma	JMJD6 GNA11 GNAQ	4.39e-06	8	128	3	C0220633
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	AMPD3 APOA5 ZPR1 MACF1 PNPLA3	1.11e-05	67	128	5	EFO_0008595, EFO_0020946
Disease	Phakomatosis cesioflammea	GNA11 GNAQ	1.87e-05	2	128	2	C3838883
Disease	Congenital hemangioma	GNA11 GNAQ	1.87e-05	2	128	2	C0235753
Disease	Port-wine stain with oculocutaneous melanosis	GNA11 GNAQ	1.87e-05	2	128	2	C1274879
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN2 SPTBN4	1.11e-04	4	128	2	DOID:0050882 (implicated_via_orthology)
Disease	diacylglycerol 33:1 measurement	APOA5 ZPR1	1.11e-04	4	128	2	EFO_0020056
Disease	Malignant melanoma of iris	GNA11 GNAQ	1.85e-04	5	128	2	C0346373
Disease	Malignant melanoma of choroid	GNA11 GNAQ	1.85e-04	5	128	2	C0346388
Disease	linoleoyl-linoleoyl-glycerol (18:2/18:2) [1] measurement	APOA5 ZPR1	1.85e-04	5	128	2	EFO_0800510
Disease	diacylglycerol 44:6 measurement	APOA5 ZPR1	1.85e-04	5	128	2	EFO_0020070
Disease	diacylglycerol 36:1 measurement	APOA5 ZPR1	2.77e-04	6	128	2	EFO_0010354
Disease	diacylglycerol 34:0 measurement	APOA5 ZPR1	3.87e-04	7	128	2	EFO_0020058
Disease	triglyceride measurement, metabolic syndrome	APOA5 ZPR1	5.14e-04	8	128	2	EFO_0000195, EFO_0004530
Disease	head and neck squamous cell carcinoma (is_marker_for)	SERPINE1 CDC73	5.14e-04	8	128	2	DOID:5520 (is_marker_for)
Disease	vitamin K measurement	ZPR1 MKI67	6.59e-04	9	128	2	EFO_0004618
Disease	apolipoprotein A-V measurement	APOA5 ZPR1	6.59e-04	9	128	2	EFO_0801387
Disease	triglyceride measurement, blood pressure	APOA5 ZPR1	6.59e-04	9	128	2	EFO_0004325, EFO_0004530
Disease	diacylglycerol 36:4 measurement	APOA5 ZPR1	6.59e-04	9	128	2	EFO_0020063
Disease	vitamin D measurement	PLB1 COPB1 APOA5 HIP1R ZPR1 GNAQ DNAH11	6.80e-04	336	128	7	EFO_0004631
Disease	docosahexaenoic acid measurement, fatty acid measurement	APOA5 ZPR1 PNPLA3	7.01e-04	40	128	3	EFO_0005110, EFO_0007761
Disease	Cutaneous Melanoma	JMJD6 GNA11 GNAQ	7.53e-04	41	128	3	C0151779
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	APOA5 ZPR1 PNPLA3	8.09e-04	42	128	3	EFO_0008317, EFO_0008596, EFO_0020945
Disease	diacylglycerol 32.2 measurement	APOA5 ZPR1	8.21e-04	10	128	2	EFO_0020055
Disease	diacylglycerol 34:3 measurement	APOA5 ZPR1	1.00e-03	11	128	2	EFO_0020059
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	APOA5 ZPR1 MACF1 PNPLA3	1.07e-03	103	128	4	EFO_0008595, EFO_0020944
Disease	level of Phosphatidylinositol (16:0_18:1) in blood serum	APOA5 ZPR1	1.20e-03	12	128	2	OBA_2045152
Disease	sterol measurement	APOA5 ZPR1	1.41e-03	13	128	2	EFO_0010231
Disease	Prostatic Neoplasms	PDHA1 APEX1 RNF43 VPS52 DHDH JMJD6 SERPINE1 PDS5A EIF3A	1.50e-03	616	128	9	C0033578
Disease	Malignant neoplasm of prostate	PDHA1 APEX1 RNF43 VPS52 DHDH JMJD6 SERPINE1 PDS5A EIF3A	1.50e-03	616	128	9	C0376358
Disease	platelet component distribution width	DENND2A WAS APOA5 LRRK2 OSER1 ST7L ZPR1 MACF1 PDS5A RHOF	1.71e-03	755	128	10	EFO_0007984
Disease	Sinus Node Dysfunction (disorder)	CACNA1D GPD1L	1.89e-03	15	128	2	C0428908
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	APOA5 ZPR1 MACF1 PNPLA3	1.94e-03	121	128	4	EFO_0008595, EFO_0020943
Disease	level of triacylglycerol (56:6) in blood serum	ZPR1 PNPLA3	2.15e-03	16	128	2	OBA_2020007
Disease	cholesteryl ester 16:1 measurement	APOA5 ZPR1	2.15e-03	16	128	2	EFO_0010342
Disease	diacylglycerol 36:2 measurement	APOA5 ZPR1	2.15e-03	16	128	2	EFO_0010355
Disease	diacylglycerol 44:7 measurement	APOA5 ZPR1	2.15e-03	16	128	2	EFO_0020069
Disease	hypertension	CACNA1D AMPD3 RNF43 GUCY1A1 L3MBTL4 SOS2	2.27e-03	307	128	6	EFO_0000537
Disease	cholesterol to total lipids in IDL percentage	ZPR1 MACF1 PNPLA3	2.28e-03	60	128	3	EFO_0022233
Disease	obesity (implicated_via_orthology)	TSC1 GNA11 PNPLA3 GNAQ PLXNB3	2.51e-03	215	128	5	DOID:9970 (implicated_via_orthology)
Disease	diacylglycerol 36:3 measurement	APOA5 ZPR1	2.73e-03	18	128	2	EFO_0020062
Disease	platelet crit	DENND2A DNAH3 KIF26A TCIM LRRK2 OSER1 ST7L SH3BP4 PNPLA3 EIF3A RHOF	2.94e-03	952	128	11	EFO_0007985
Disease	Hypertriglyceridemia	APOA5 ZPR1	3.04e-03	19	128	2	EFO_0004211
Disease	bilirubin measurement	APOA5 ZPR1 PNPLA3 L3MBTL4 ARMC6 DNAH11 SOS2	3.23e-03	442	128	7	EFO_0004570
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	COPB1 APOA5 ZPR1 PNPLA3 DNAH11	3.29e-03	229	128	5	EFO_0004639, EFO_0008317
Disease	citrulline measurement	HMCN2 PTPRE	3.37e-03	20	128	2	EFO_0009777
Disease	free cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	ZPR1 PNPLA3	3.71e-03	21	128	2	EFO_0022277
Disease	cardiovascular disease	CACNA1D PLB1 CLUAP1 RNF43 GUCY1A1 ZPR1 SOS2	3.88e-03	457	128	7	EFO_0000319

Protein segments in the cluster

Peptide	Gene	Start	Entry
VEAIREALVDKAEAF	CYP2B6	81	P20813
FRSQAAVIDEIVDTT	CATSPER1	756	Q8NEC5
IAIDQESQKIAFARA	VCAN	1551	P13611
TALKQRSFVDAEVDV	CDC73	206	Q6P1J9
RSFVDAEVDVTRDIV	CDC73	211	Q6P1J9
NAIIAFEDADLSLVV	ALDH7A1	301	P49419
REALNTKEAVVFEAV	BTBD6	291	Q96KE9
IAQETFDAAVRENIE	ARMC6	31	Q6NXE6
LEAEAVFRAITIASQ	DPYSL3	231	Q14195
QFIEFANTVAEKVDR	CACFD1	81	Q9UGQ2
DAEERKVTAIQTEVF	DNAH11	3156	Q96DT5
EEIQRVAEVANAVAF	ABCB10	601	Q9NRK6
NTVARFAADLAEELV	AKAP11	641	Q9UKA4
IAAFTRAIDQETEEV	APOA5	296	Q6Q788
RVIVAEFDSFVLVTA	APEX1	156	P27695
FIVQTAEIAEIARLS	CEP170B	1316	Q9Y4F5
RNEVVVQAAAVRVSD	CCDC87	436	Q9NVE4
DEQIDILVATDVAAR	DDX27	511	Q96GQ7
SEVDEQVRLLAEKVF	AMPD3	11	Q01432
EVQKDQFVFREIIAD	RANBP17	121	Q9H2T7
DDKVAEAAIQIFRNT	PDS5A	691	Q29RF7
KDATNVAAAFEEAVR	RAB9A	156	P51151
VAAAFEEAVRRVLAT	RAB9A	161	P51151
KDDTNVTVAFEEAVR	RAB9B	156	Q9NP90
VTVAFEEAVRQVLAV	RAB9B	161	Q9NP90
NASEKTVVEALFQRD	NUP107	246	P57740
QLVREVDVEKVSAFE	GNAQ	111	P50148
ATDTENIRFVFAAVK	GNAQ	331	P50148
EFALTAVAEEVNAIL	PTPRN2	996	Q92932
SFEEVAREGADVIVN	DAO	166	P14920
VNVEVTRIKVFDADE	DSG2	286	Q14126
EVVDARLVSVFDARE	HECW2	1431	Q9P2P5
HAEQKVDVFEFVSRI	PTPRE	356	P23469
VAELTVTDLFRAIDQ	LPCAT1	451	Q8NF37
VERADALQLSVEEFV	JMJD6	46	Q6NYC1
ADVAIELKAVFTDRQ	LGALSL	81	Q3ZCW2
QVVELSFIRAEIFAE	ZBTB33	66	Q86T24
LSEAVQDADLLVFVI	GPD1L	81	Q8N335
TEFAVLEEQRVELSV	IMPG1	226	Q17R60
ENTQAEARKDFVVAV	HMCN2	3206	Q8NDA2
VDRIFSFEINVSVAI	C2	281	P06681
LRDVNLDNDVVVSVF	EDEM3	131	Q9BZQ6
LDNDVVVSVFETNIR	EDEM3	136	Q9BZQ6
RVVEVLQDSVDFDID	EDEM2	96	Q9BV94
AEAEQKAFEVIATER	CBFA2T2	461	O43439
FDVRVSDNVDAILAV	PLXNB3	1771	Q9ULL4
EATREFNVVIVAVDS	PCDH7	496	O60245
SANKVFEELTDVERQ	PDE6C	246	P51160
NVLVSDFRSKDEVVD	PNPLA3	126	Q9NST1
AAADVLEFVREAIQR	COPB1	416	P53618
VLFERVSEEQLTEFV	LRRK2	186	Q5S007
SVSFEQAVRILQDDV	KRR1	126	Q13601
AEAAVAAVAVADTVR	KIF26A	246	Q9ULI4
ATIVDVDDQRVKVHF	L3MBTL4	316	Q8NA19
VEKAVRAARQAADFT	QPRT	181	Q15274
AEQQITEVFVLAERI	MKI67	3101	P46013
RFVAAEQSVALGEEV	HSPA12B	576	Q96MM6
DEQDQITFVTRAVRV	HUWE1	421	Q7Z6Z7
TFEEDKVNSALVVDR	NBPF1	501	Q3BBV0
IQQAFVERDILTFAE	MAST1	416	Q9Y2H9
IVDIFSDQRVTLVEA	MACF1	2736	Q9UPN3
ETLVFSENAVVALRD	KCNJ14	196	Q9UNX9
AAFQAETQELLDVIV	SBF1	291	O95248
ITEKIDVAFVDRADI	TRIP13	301	Q15645
QVEIIRDFDVAVVTF	PARP14	181	Q460N5
RDFDVAVVTFQKHID	PARP14	186	Q460N5
AAAFREVRVQSVVVE	ARHGAP33	486	O14559
VREALVQQAEVFSDR	CYP2U1	136	Q7Z449
EEAELEANSVFRQKV	CMPK2	396	Q5EBM0
EAEREQFDKTQAISI	HIP1R	21	O75146
TNRVIFLEDDDIAAV	GFPT2	271	O94808
DEFNRIEVEVLSVVA	DNAH3	1481	Q8TD57
NEVVSEAFVRFFVEI	DENND2A	896	Q9ULE3
FVDAFQLERAIVDAA	EIF3A	461	Q14152
ATDTENIRFVFAAVK	GNA11	331	P29992
ARDVFAQVREATADI	CTR9	666	Q6PD62
SEVDRVILKANETFA	ABCA2	466	Q9BZC7
IFNRVVLENEAVRAA	COPG2	476	Q9UBF2
VVAVAARDLSRAKEF	DHDH	31	Q9UQ10
IVNFSAEEISDAIRE	DYNC1H1	3351	Q14204
RAVVIFANDEDIKQI	GRM7	281	Q14831
DVESFVAAAEILKER	PRPSAP1	261	Q14558
KDAFVILVENALRVA	SLC44A1	516	Q8WWI5
FDEFNRISVEVLSVV	DNAH9	1921	Q9NYC9
ARFLENVAAAETEKQ	FHOD1	441	Q9Y613
VFLAIAVDNLADAES	CACNA1D	746	Q01668
EEVALRATAENEFVA	KRT83	201	P78385
QSFEALSERAVAVVV	PSMD14	131	O00487
AAAEEINTKEVAQRI	ONECUT3	316	O60422
QVDFSEVERARFIIN	SERPINE1	146	P05121
EEVVFVRLNTEVASV	IRS4	261	O14654
VEDVFREAAKVALSA	RHOF	181	Q9HBH0
AAQRLATVVNDERFV	XAB2	196	Q9HCS7
FVVDSAAFQREVKDV	SRPRB	141	Q9Y5M8
EEVAIKRENFVAEIQ	HARS2	486	P49590
RADDLIETAKVFVNN	TMEM26	121	Q6ZUK4
CIVEAENFEERVAVL	SOS2	836	Q07890
VIKFDTEEEAIAIAN	ALDH5A1	446	P51649
DFTLRVQVKDDQEAI	SH3BP4	586	Q9P0V3
VQFSVEDVVEVNILR	TDRD9	1276	Q8NDG6
AVVEEETSFLRARVQ	MTCP1	31	P56278
EEIFDSRIAAQAVTK	GIMAP7	31	Q8NHV1
EKVDAVRLINIVFDE	PPWD1	351	Q96BP3
AVLFDITEDRAAAEQ	RNF43	136	Q68DV7
SAAEAAEVILRVDNI	CCT2	506	P78371
VLVEITDVDFAALKA	SHCBP1	126	Q8NEM2
TDVDFAALKAVVRLA	SHCBP1	131	Q8NEM2
DFASEAEVAVQKEIR	STARD9	2461	Q9P2P6
FVNLVDLSEVAEVSR	PLB1	211	Q6P1J6
QARVFVDDVTIEDLS	OSER1	256	Q9NX31
AVRALEQFATVVEAK	ACADVL	536	P49748
VDTEQDRVFFIKAIA	CLUAP1	56	Q96AJ1
ESADVVAFILRQVIE	PITPNM1	866	O00562
VEVENFVLRVAAEFS	VPS52	541	Q8N1B4
ANKDATAERIDEFIV	ZPR1	166	O75312
VRDDVTAVFKENLNS	TSC1	21	Q92574
FILFRNETVDVEDIV	ZCCHC3	256	Q9NUD5
EVRKEIEDAAQFATA	PDHA1	341	P08559
VQAVDAVAAELAAER	SPTBN2	481	O15020
EAAAVRDISEVSVFD	RPS26P11	46	Q5JNZ5
EVQAAAVAVAEAEAR	TRO	646	Q12816
FAAASREVLAVEAEL	REX1BD	111	Q96EN9
RVFAAEAVTADSEVL	TIMMDC1	21	Q9NPL8
SAAALDVLANVFREE	TNPO2	376	O14787
TLVVAAARAEKEAFV	TMEM131	51	Q92545
AARAEKEAFVQSESI	TMEM131	56	Q92545
EDEAQAFRALVQEKI	WAS	131	P42768
SEVTAVFTDKDANVR	TEX10	101	Q9NXF1
VFTDKDANVRLAAVQ	TEX10	106	Q9NXF1
ALQVRVVEAEQLFAE	SPTBN4	851	Q9H254
EATTIVDAERLFKQA	ST7L	246	Q8TDW4
FVEQTDIVALAARAI	USF3	1126	Q68DE3
EAVTFKDVAVVFSRE	ZNF227	21	Q86WZ6
AFNSAERAVTEVREV	TOGARAM1	1461	Q9Y4F4
IIFAIDQDVEEKTRA	TCIM	66	Q9NR00
AAVADAILRAQEEIF	PLD2	346	O14939
VLKVFAARDDEAAAV	XRCC5	361	P13010
REDFEKTIAEQAVAA	GUCY1A1	111	Q02108
DEINKRTAAENEFVA	KRT75	241	O95678
EVEINRRTTAENEFV	KRT74	231	Q7RTS7
LVTAVEKFEAEAAAL	NAALADL1	621	Q9UQQ1