Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	KASH	SYNE3 SYNE2	2.01e-04	4	109	2	IPR012315
Domain	KASH	SYNE3 SYNE2	2.01e-04	4	109	2	PS51049
Domain	KASH	SYNE3 SYNE2	2.01e-04	4	109	2	SM01249
Domain	KASH	SYNE3 SYNE2	2.01e-04	4	109	2	PF10541
Domain	Spectrin	SPTBN5 SYNE3 SYNE2	3.15e-04	23	109	3	PF00435
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	RAP1GDS1 DNAJC16 PEX1 CEMIP2 PREB SENP1 SYNE3 SYNE2 NUP210	2.16e-05	468	112	9	31056421
Pubmed	Functional characterization of SAMD9, a protein deficient in normophosphatemic familial tumoral calcinosis.	SAMD9 RGL2	3.08e-05	3	112	2	21160498
Pubmed	Novel candidate genes putatively involved in stress fracture predisposition detected by whole-exome sequencing.	SLC6A18 NEB	3.08e-05	3	112	2	25023003
Pubmed	The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction.	SYNE3 SYNE2	3.08e-05	3	112	2	23336069
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	AARS1 CEP85 SAMD9 DNAJC16 PEX1 LMBRD2 CEMIP2 PREB CTR9 MID1	4.97e-05	650	112	10	38777146
Pubmed	Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver.	ABCA9 ABCA8	6.14e-05	4	112	2	16445568
Pubmed	Mutations in the microtubule-associated protein 1A (Map1a) gene cause Purkinje cell degeneration.	AARS1 MAP1A	6.14e-05	4	112	2	25788676
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRBA2 NEB RNF17 KIAA2013 SEPHS2 NRXN3 LATS2 PHF20L1 CTR9 SYNE2 SMARCA1 CEP295 OTUD3 DNAJC3 DOP1A	6.16e-05	1442	112	15	35575683
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DNAJC16 ADGRV1 TENM4 SYNE2 PHLPP1 BAIAP3	9.27e-05	225	112	6	12168954
Pubmed	Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.	ABCA9 ABCA8	1.02e-04	5	112	2	12532264
Pubmed	Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.	IPO7 IPO4	1.02e-04	5	112	2	27528606
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE3 SYNE2	1.02e-04	5	112	2	18396275
Pubmed	Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.	IPO7 IPO4	1.02e-04	5	112	2	19788888
Pubmed	Generation of mice with a conditional Foxp2 null allele.	GAD2 EDIL3	1.53e-04	6	112	2	17619227
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SYNE3 SYNE2	1.53e-04	6	112	2	33058875
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE3 SYNE2	1.53e-04	6	112	2	18827015
Pubmed	SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA.	GAD2 EDIL3	1.53e-04	6	112	2	26206889
Pubmed	Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.	IPO7 IPO4	2.84e-04	8	112	2	27114554
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	MAN2B2 DNAJC16 SYNE2 NINL	3.40e-04	102	112	4	10231032
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	TRRAP SPTBN5 CCT5 SYNE2 NINL	3.59e-04	187	112	5	26460568
Pubmed	Gene expression analysis of the embryonic subplate.	SLITRK3 ABCA8 KCNT2 SYNE2 TACC3	4.45e-04	196	112	5	21862448
Pubmed	Strain background effects and genetic modifiers of hearing in mice.	MAP1A ADGRV1	5.55e-04	11	112	2	16579977
Pubmed	A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.	SYNE3 SYNE2	5.55e-04	11	112	2	22826121
Pubmed	C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.	IPO7 MRPS27 IPO4 CCT5	6.09e-04	119	112	4	35776542
Pubmed	The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.	IPO7 IPO4 KIAA2013 CCT5 NUP210 MID1	6.12e-04	320	112	6	28685749
Pubmed	LncRNA DUXAP9-206 directly binds with Cbl-b to augment EGFR signaling and promotes non-small cell lung cancer progression.	SAMD9 CCT5	6.64e-04	12	112	2	30515972
Pubmed	p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes.	SYNE3 SYNE2	6.64e-04	12	112	2	28595999
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	FSIP2 SENP1 CCT5 SYNE2	6.89e-04	123	112	4	26912792
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CDR2 STK17A PEX1 TRRAP MKNK1 PREB ZCCHC4 PHKB LATS2 CTR9	7.33e-04	910	112	10	36736316
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	IPO7 PEX1 RNF17 TRRAP ESYT3 WIZ CCT5 SYNE2 NUP210	7.62e-04	754	112	9	35906200
Pubmed	Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility.	EDIL3 ESYT3	9.12e-04	14	112	2	27399837
Pubmed	The contribution of rare and common variants in 30 genes to risk nicotine dependence.	GABBR2 NRXN3	9.12e-04	14	112	2	25450229
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	AARS1 IPO7 DNAJC16 PEX1 IPO4 INTS8 KIAA2013 PREB NUP210 DNAJC3	9.52e-04	942	112	10	31073040
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	MYO7B DNAJC16 NEB SENP1 CGNL1	9.88e-04	234	112	5	36243803
Pubmed	Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.	TRRAP MED17	1.05e-03	15	112	2	18418385
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ZNF536 IPO7 MRPS27 NEB SYNE2 CEP295 MED17 FER1L5	1.10e-03	638	112	8	31182584
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MAN2B2 MRPS27 ABCA8 KIAA2013 NUP210 CGNL1 DOP1A	1.11e-03	493	112	7	15368895
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	MYO7B IRF5 SPTBN5 NUP210	1.18e-03	142	112	4	19851296
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	AARS1 SAMD9 DCPS ZNF397 EDIL3 INTS8 CCT5 GCLM SMARCA1	1.18e-03	803	112	9	36517590
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	MYO7B IRF5 SPTBN5 NUP210	1.21e-03	143	112	4	20198315
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	AARS1 CEP85 IPO7 DNAJC16 MRPS27 IPO4 CCT5 CTR9 NUP210 DNAJC3	1.22e-03	974	112	10	28675297
Pubmed	Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse.	CACNA1S GAD2 NRXN3	1.34e-03	67	112	3	16987237
Pubmed	Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.	TRRAP SMARCA1	1.35e-03	17	112	2	21653943
Pubmed	An essential role for frizzled 5 in mammalian ocular development.	GAD2 EDIL3	1.35e-03	17	112	2	18832390
Pubmed	Cellular resolution maps of X chromosome inactivation: implications for neural development, function, and disease.	GAD2 EDIL3	1.35e-03	17	112	2	24411735
Pubmed	Mutation specific functions of EGFR result in a mutation-specific downstream pathway activation.	IPO7 DNAJC16 PIK3CB	1.40e-03	68	112	3	25754235
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	TRRAP CTR9 MED17	1.46e-03	69	112	3	28481362
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	CACNA1S ADGRV1 NEB CGNL1	1.51e-03	152	112	4	34299191
Pubmed	USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.	TRRAP SMARCA1	1.52e-03	18	112	2	17846119
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	GAD2 ZNF536 FIGNL2 ADAMTS8 GABBR2 ANKRD33 TENM4 SMARCA1	1.55e-03	674	112	8	37196079
Pubmed	Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea.	MYO7B EDIL3	1.70e-03	19	112	2	34124068
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ITGA11 MAN2B2 DNAJC16 LMBRD2 EDIL3 CEMIP2 KIAA2013 TSKU TMEM245 NUP210 DNAJC3	1.74e-03	1201	112	11	35696571
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	AARS1 RAP1GDS1 IPO7 WIZ SYNE2 DNAJC3	1.87e-03	398	112	6	35016035
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CEP85 IPO7 CEMIP2 PHKB WIZ CCT5 CTR9 SYNE2 NUP210 PHLPP1	2.11e-03	1049	112	10	27880917
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	TRRAP WIZ MED17 CABIN1	2.13e-03	167	112	4	20362541
Pubmed	The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification.	IPO7 ZNF397	2.28e-03	22	112	2	31403225
Pubmed	Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala.	GAD2 SLITRK3	2.28e-03	22	112	2	38736483
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CTR9 SYNE2 PHLPP1	2.83e-03	87	112	3	12465718
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GAD2 AARS1 RAP1GDS1 CEP85 ADAMTS8 EDIL3 INTS8 WIZ CTR9 SHARPIN CABIN1	2.93e-03	1285	112	11	35914814
Pubmed	A large set of estrogen receptor β-interacting proteins identified by tandem affinity purification in hormone-responsive human breast cancer cell nuclei.	MRPS27 MED17	2.94e-03	25	112	2	21182203
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	ABRA ADGRV1 RWDD3 PLEKHN1 SYNE2 SHARPIN RGL2 BAIAP3	3.00e-03	750	112	8	11230166
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	IRF5 TRRAP KIAA2013 SEPHS2 SYNE3 LATS2 WIZ NINL CABIN1 RGL2	3.06e-03	1105	112	10	35748872
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	IPO7 DNAJC16 MRPS27 IPO4 CEMIP2 PREB SENP1 SYNE3 CTR9 SYNE2 NUP210 DNAJC3	3.07e-03	1487	112	12	33957083
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	RAP1GDS1 MAN2B2 IPO7 MRPS27 PEX1 LMBRD2 NUP210 NINL	3.10e-03	754	112	8	33060197
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MAN2B2 SLITRK3 ADGRV1 TRRAP INTS8 PHKB SENP1 LATS2 NUP210 BAIAP3 DNAJC3 DOP1A	3.10e-03	1489	112	12	28611215
Pubmed	Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.	SYNE2 PHLPP1	3.18e-03	26	112	2	25820252
Pubmed	Inhibition of UBE2D3 expression attenuates radiosensitivity of MCF-7 human breast cancer cells by increasing hTERT expression and activity.	PHF20L1 CCT5	3.18e-03	26	112	2	23741361
Pubmed	Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.	KL PAPPA	3.18e-03	26	112	2	33905568
Pubmed	Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.	IPO7 IPO4	3.18e-03	26	112	2	23181366
Pubmed	OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.	SENP1 LATS2 CCT5	3.21e-03	91	112	3	30472188
Interaction	SYNE3 interactions	CEP85 DCPS DNAJC16 PEX1 SENP1 SYNE3 LATS2 SYNE2 NUP210 CEP295 CGNL1 DNAJC3	4.65e-06	444	108	12	int:SYNE3
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE3 SYNE2	8.08e-05	4	67	2	1252
GeneFamily	ATP binding cassette subfamily A	ABCA9 ABCA8	1.20e-03	14	67	2	805
GeneFamily	Armadillo repeat containing\|Importins	IPO7 IPO4	1.99e-03	18	67	2	596
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000	GAD2 ZNF536 MAP1A ADGRV1 CEMIP2 NRXN3 LATS2 PIK3CB TMEM245 SYNE2 NUP210 NINL PHLPP1 TACC3 MED17 RGL2	3.49e-05	979	108	16	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500	GAD2 ZNF536 MAP1A ADGRV1 CEMIP2 NRXN3 PIK3CB SYNE2 NUP210 NINL PHLPP1	3.50e-05	482	108	11	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	ZNF536 MAP1A ADGRV1 PREB PIK3CB SYNE2 NUP210 PHLPP1 PAPPA CEP295 EPHX4	4.70e-05	498	108	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	CDR2 MAP1A ADGRV1 INTS8 CEMIP2 NRXN3 PIK3CB PHLPP1 ACMSD	7.56e-05	350	108	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K5
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDR2 ZNF536 ITGA11 ZCCHC4 TENM4 WIZ CPT1C SMARCA1	2.07e-08	184	111	8	a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCell	IIF-Lymphocyte-T_NK-ILC\|IIF / Disease, Lineage and Cell Type	ISYNA1 KRBA2 B3GNT7 NEB PLEKHN1 FER1L5	2.95e-06	159	111	6	55e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	CDR2 PLEKHN1 CEMIP2 EPG5 SYNE2 CEP295	3.79e-06	166	111	6	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC74B ZNF536 SLITRK3 ABCA8 NRXN3 TENM4	6.22e-06	181	111	6	3aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC74B ZNF536 SLITRK3 ABCA8 NRXN3 TENM4	6.22e-06	181	111	6	997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell	5'-Adult-Appendix-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC74B ZNF536 SLITRK3 ABCA8 NRXN3 TENM4	6.22e-06	181	111	6	e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	SLC6A18 EDIL3 ABCA8 KCNT2 CST6 CGNL1	6.63e-06	183	111	6	6821dca076318115d360ff426eb1218cfe104063
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC6A18 GLYAT MYO7B TENM4 SYNE2 ACMSD	6.84e-06	184	111	6	9434731f651820b05335085582960f08fbf895de
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA9 ABCA8 CNTNAP5 TENM4 PAPPA CGNL1	6.84e-06	184	111	6	4d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	GLYAT MYO7B KCNT2 SYNE2 PAPPA ACMSD	7.97e-06	189	111	6	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GLYAT MYO7B SYNE2 NINL PAPPA CGNL1	8.46e-06	191	111	6	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GLYAT MYO7B SYNE2 NINL PAPPA CGNL1	8.46e-06	191	111	6	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	ITGA11 ABCA9 ABCA8 TENM4 KCNT2 PAPPA	9.25e-06	194	111	6	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-dn_T\|Bac-SEP / Disease, condition lineage and cell class	B3GNT7 RWDD3 MKNK1 SEPHS2 CTR9 RGL2	1.07e-05	199	111	6	4150a479b80596accf679b37aa9b0ac15cc132b2
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 NMU NRXN3 SYNE3 MID1 PAPPA	1.10e-05	200	111	6	858421b91f5207b7934b5c219752cb9322a3da31
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 NMU NRXN3 SYNE3 MID1 PAPPA	1.10e-05	200	111	6	a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF536 ABCA9 ABCA8 TENM4 KCNT2 PAPPA	1.10e-05	200	111	6	fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 NMU NRXN3 SYNE3 MID1 PAPPA	1.10e-05	200	111	6	2131c8e7fa054b79906eaf60536da892438b09cd
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	PLEKHG4 PLEKHN1 ESYT3 RGL2 BAIAP3	1.61e-05	126	111	5	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Interneuron\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	GAD2 ZNF536 CEMIP2 NRXN3	1.87e-05	63	111	4	c10d344bf32a091deb79e1f128f7dd5e9f4abaa3
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Adora1_(Striatum,_interneuron)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CPLANE2 NEB SPTBN5 FER1L5	2.25e-05	66	111	4	d6b202d9f5bebaac23b34b689ad306549dec0593
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Adora1_(Striatum,_interneuron)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CPLANE2 NEB SPTBN5 FER1L5	2.25e-05	66	111	4	4a714cf035b22da103054098f85f9170c56e9e83
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(peripeduncular_nucleus_&_posterior_intralaminar_thalamic_nucleus_(PP_&_PIL))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CPLANE2 MYO7B PPP1R3A FER1L5	2.25e-05	66	111	4	85e0027bf0d4ebdcb6cac358aedd1d74aa83c612
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(peripeduncular_nucleus_&_posterior_intralaminar_thalamic_nucleus_(PP_&_PIL))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CPLANE2 MYO7B PPP1R3A FER1L5	2.25e-05	66	111	4	6cf03dd1db7607684cdcca7df08933f8cdc3adef
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-OPC_related\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ITGA11 DNAJC16 ZNF630 LATS2 MID1	2.41e-05	137	111	5	264d5e06c37d1a9ef7748091b67d2a5aa803096e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-OPC_related-Oligodendrocyte/OPC\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ITGA11 DNAJC16 ZNF630 LATS2 MID1	2.41e-05	137	111	5	8ce463d1d74ac0ce80b812217d6bd76a788f14d2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 ABCA9 ABCA8 KCNT2 CPT1C	3.72e-05	150	111	5	1270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 ABCA9 ABCA8 KCNT2 CPT1C	3.72e-05	150	111	5	156118ce1d69522624196410cba18b8354cd0bb4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDR2 ADAMTS8 EDIL3 PPP1R3A FSIP2	3.84e-05	151	111	5	16fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Interneuron\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	GAD2 ZNF536 CEMIP2 NRXN3	4.35e-05	78	111	4	8ad496ccbffb62a50f195c3789a95d8c80e2272d
ToppCell	368C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LMBRD2 EDIL3 ABCA9 CEMIP2 FSIP2	4.48e-05	156	111	5	4877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell	368C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LMBRD2 EDIL3 ABCA9 CEMIP2 FSIP2	4.48e-05	156	111	5	1d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF536 ABCA9 ABCA8 CNTNAP5 CPT1C	4.62e-05	157	111	5	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	P28-Hematopoietic-Erythroid\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDR2 DNAJC16 TSKU TACC3	5.55e-05	83	111	4	e548e5c7b16c895b360a00f3d6fc1a7eb3d19294
ToppCell	P28-Hematopoietic-Erythroid-enucleate_erythrocyte\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDR2 DNAJC16 TSKU TACC3	5.55e-05	83	111	4	c7ff56d4c7582fc497057cf3d5497fbd13c183cc
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1S IPO7 RNF17 PLEKHN1 CEP295	5.85e-05	165	111	5	c39f0479955c4e23921f7a450d3bc251a002200f
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A18 CDR2 TSKU PHKB GCLM	6.37e-05	168	111	5	35ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	ZNF536 ADAMTS8 ABCA8 NRXN3 PAPPA	6.55e-05	169	111	5	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRV1 RNF17 ABCA8 KCNT2 DOP1A	6.92e-05	171	111	5	b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue-3\|TCGA-Breast / Sample_Type by Project: Shred V9	GLYAT ABCA9 ABCA8 KL SYNE3	7.52e-05	174	111	5	7f8f5fafae08676d2b90cab9802c3c9320f1370e
ToppCell	TCGA-Breast-Solid_Tissue_Normal\|TCGA-Breast / Sample_Type by Project: Shred V9	GLYAT ABCA9 ABCA8 KL SYNE3	7.52e-05	174	111	5	e2f240d60bffbe8e6d60f0bb405b231bd3c96875
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF536 EDIL3 ABCA8 KCNT2 PAPPA	7.52e-05	174	111	5	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue\|TCGA-Breast / Sample_Type by Project: Shred V9	GLYAT ABCA9 ABCA8 KL SYNE3	7.52e-05	174	111	5	0f3ec0d0d4344e10c9b48adc9174123f6402dc51
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue\|TCGA-Breast / Sample_Type by Project: Shred V9	GLYAT ABCA9 ABCA8 KL SYNE3	7.52e-05	174	111	5	1aadbf2642b6d1320ceabd92e6ff59e11f16c315
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA9 ABCA8 TENM4 PAPPA CGNL1	8.15e-05	177	111	5	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 ABCA9 ABCA8 KCNT2 FBXO4	8.15e-05	177	111	5	b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell	ILEUM-inflamed-(9)_Enteric_neurons\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZNF536 ABCA9 ABCA8 NRXN3 PAPPA	8.37e-05	178	111	5	d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCell	ILEUM-inflamed-(9)_Neuro_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZNF536 ABCA9 ABCA8 NRXN3 PAPPA	8.37e-05	178	111	5	611504b0a9e6318b18fba83787b03f9245c82252
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPO7 ADAMTS8 KCNT2 SMARCA1 BAIAP3	8.59e-05	179	111	5	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	facs-MAT-Fat-3m-Epithelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 LMBRD2 CNTNAP5 GP9	8.65e-05	93	111	4	dbfaa7f23d25f5c286ab7ca3ca795b734cb95153
ToppCell	facs-MAT-Fat-3m-Epithelial-epithelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 LMBRD2 CNTNAP5 GP9	8.65e-05	93	111	4	0d6d1d8dd9c91ba31eb35a4b5979d087890936c1
ToppCell	facs-MAT-Fat-3m-Epithelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 LMBRD2 CNTNAP5 GP9	8.65e-05	93	111	4	abffb1fd5a919b7c08e62e1c3c08a8dd8783a4ca
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GLYAT SYNE2 PAPPA CGNL1 ACMSD	8.82e-05	180	111	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	droplet-Kidney\|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A18 GLYAT SEPHS2 KL CGNL1	8.82e-05	180	111	5	7e5f497699876ac8e1ce780626c6f5a1f6f5f079
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GLYAT MYO7B PAPPA CGNL1 ACMSD	8.82e-05	180	111	5	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABRA MAP1A NRXN3 NINL PAPPA	8.82e-05	180	111	5	d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABRA MAP1A NRXN3 NINL PAPPA	8.82e-05	180	111	5	573308d43425d9fba20787abdb7f8efefc48efb5
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CPLANE2 ZNF536 MAP1A ZCCHC4 PAPPA	9.29e-05	182	111	5	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ITGA11 ABCA9 ABCA8 TENM4 KCNT2	9.29e-05	182	111	5	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC6A18 GLYAT MYO7B ADGRV1 ACMSD	9.53e-05	183	111	5	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NMU MID1 PAPPA BAIAP3	9.53e-05	183	111	5	439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	CDR2 ZNF397 PHKB LATS2 MBTPS2	9.78e-05	184	111	5	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-3\|World / Primary Cells by Cluster	GAD2 ZNF536 RWDD3 CEMIP2 NRXN3	9.78e-05	184	111	5	907ba412166bcb0526c5be0b06a76b6bd37c5a35
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ITGA11 ABCA9 ABCA8 TENM4 KCNT2	1.00e-04	185	111	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GLYAT SYNE2 PAPPA CGNL1 ACMSD	1.00e-04	185	111	5	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PLEKHN1 NMU NRXN3 CST6 PAPPA	1.05e-04	187	111	5	8e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	GLYAT MYO7B PAPPA CGNL1 ACMSD	1.05e-04	187	111	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GLYAT SYNE2 PAPPA CGNL1 ACMSD	1.05e-04	187	111	5	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	GLYAT MYO7B SYNE2 PAPPA ACMSD	1.05e-04	187	111	5	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Early_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ISYNA1 PLEKHN1 NMU CST6 PAPPA	1.08e-04	188	111	5	6151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ITGA11 ABCA9 ABCA8 TENM4 KCNT2	1.08e-04	188	111	5	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDR2 EDIL3 PIK3CB SYNE2 MID1	1.11e-04	189	111	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 NMU SYNE3 MID1 PAPPA	1.11e-04	189	111	5	06c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PLEKHN1 NMU NRXN3 CST6 PAPPA	1.16e-04	191	111	5	4c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCell	Control-Plasmablast\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	AARS1 PLEKHN1 PREB WT1-AS DNAJC3	1.16e-04	191	111	5	3df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCell	droplet-Heart-HEART-1m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR2 PLEKHN1 WT1-AS GCLM	1.19e-04	101	111	4	6c4524be89cf3eb06769c2963dcded3da1e71ca0
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA9 ABCA8 KCNT2 MID1 PAPPA	1.19e-04	192	111	5	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ITGA11 ABCA9 ABCA8 TENM4 KCNT2	1.19e-04	192	111	5	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	ABCA9 ABCA8 KCNT2 MID1 PAPPA	1.19e-04	192	111	5	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	DNAJC16 ADGRV1 MBTPS2 ZBED6 CTR9	1.22e-04	193	111	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	ZNF536 ABCA9 TENM4 KCNT2 PAPPA	1.22e-04	193	111	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 ZNF536 NMU SYNE3 PAPPA	1.25e-04	194	111	5	e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 ABCA9 ABCA8 NRXN3 KCNT2	1.25e-04	194	111	5	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 ABCA9 ABCA8 NRXN3 KCNT2	1.25e-04	194	111	5	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	wk_08-11-Mesenchymal-Mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ISYNA1 PLEKHN1 NMU CST6 PAPPA	1.28e-04	195	111	5	9016a44b521214546a55a822ebdef5b5312206d2
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ITGA11 ABCA9 ABCA8 KCNT2 PAPPA	1.28e-04	195	111	5	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDR2 STK17A RNF17 CEMIP2 SYNE2	1.31e-04	196	111	5	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 ABCA9 ABCA8 NRXN3 KCNT2	1.31e-04	196	111	5	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	ABCA9 ABCA8 KCNT2 MID1 PAPPA	1.31e-04	196	111	5	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 ITGA11 EDIL3 WT1-AS KCNT2	1.31e-04	196	111	5	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLITRK3 ABCA9 ABCA8 TENM4 KCNT2	1.35e-04	197	111	5	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 ABCA9 ABCA8 NRXN3 KCNT2	1.35e-04	197	111	5	80e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF536 SLITRK3 ABCA8 TENM4 KCNT2	1.35e-04	197	111	5	ee8f7def9d5af7b1e636830a4ea1da158d02f25a
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF536 STK17A ADGRV1 ABCA8 NRXN3	1.38e-04	198	111	5	36c97eb71b89bac01cabd6a8b728e5a20e52d2a3
ToppCell	mild_COVID-19_(asymptomatic)-NK\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	STK17A B3GNT7 CEMIP2 EPG5 SYNE2	1.38e-04	198	111	5	1e43181c13e054570046c7a973ddc1c586e259b0
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF536 EDIL3 ABCA8 KCNT2 PAPPA	1.38e-04	198	111	5	7582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TSKU TENM4 SMARCA1 PAPPA FER1L5	1.41e-04	199	111	5	6200618e029063486719479c41eaf31798bd13cf
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA9 ABCA8 MID1 PAPPA CGNL1	1.41e-04	199	111	5	9846d6a31635fde759d55674631c11ab9270a603
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 ZNF536 SAMD9 NMU NRXN3	1.44e-04	200	111	5	a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ABCA9 ABCA8 CEMIP2 SYNE2 CGNL1	1.44e-04	200	111	5	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
Disease	energy intake measurement	FIGNL2 ANKRD33	1.34e-04	5	109	2	EFO_0009374
Disease	kidney failure (implicated_via_orthology)	KL ACMSD	1.34e-04	5	109	2	DOID:1074 (implicated_via_orthology)
Disease	phospholipase A2, membrane associated measurement	ABCA8 OTUD3	5.97e-04	10	109	2	EFO_0008259
Disease	Congenital myopathy (disorder)	CACNA1S NEB	8.71e-04	12	109	2	C0270960
Disease	cortisol measurement	MKNK1 CNTNAP5	2.46e-03	20	109	2	EFO_0005843

Protein segments in the cluster

Peptide	Gene	Start	Entry
PHLQINWTGLTNLLD	ESYT3	246	A0FGR9
WHQVLQLSLIQTEQN	EPG5	2421	Q9HCE0
QSNLSPLQLAVLHWQ	BAIAP3	446	O94812
NIIQPLLHAQWVLGD	ADAMTS8	826	Q9UP79
NALWPNLTVRQHLEV	ABCA9	1371	Q8IUA7
EHLQPYWEELENLVQ	GCLM	141	P48507
NLLNHPWLVQDTEAE	FBXO4	351	Q9UKT5
QAIWGLADQLHQPVN	ADGRV1	5626	Q8WXG9
HVNEWDLNAQELFPV	ACMSD	146	Q8TDX5
VGQAWLNQVLQRHDI	DOP1A	976	Q5JWR5
ELWNTNLLQTQELQH	CCDC74B	281	Q96LY2
VLIPDLKWNQQQLDD	DCPS	201	Q96C86
KLALQWHPDNFQNEE	DNAJC3	416	Q13217
WACVHNDPTQLQAIL	ANKRD33	101	Q7Z3H0
LSINPNNHSWLIIQA	INTS8	826	Q75QN2
QNTLVPGALELAWQH	ISYNA1	281	Q9NPH2
LQIQVNLSANPWHCD	LRRC3C	151	A6NJW4
HILQVPVWNQQEVEI	NUP210	436	Q8TEM1
NWELADQPQNLEEIL	GAD2	146	Q05329
QWGENLQVTLIPTHD	MAP1A	2746	P78559
LQPEQQLQLWNEIDD	NMU	46	P48645
INWENTLHIPAQVKL	LATS2	926	Q9NRM7
LSEASHWLQQDQPDI	EPHX4	331	Q8IUS5
HWLQQDQPDIVNKLI	EPHX4	336	Q8IUS5
GSPELINWKQHLQIQ	GLYAT	91	Q6IB77
INWKQHLQIQSSQPS	GLYAT	96	Q6IB77
PQHCDVAQVQNWLLK	FSIP2	176	Q5CZC0
PLELINQQNLTEWIE	IPO7	216	O95373
DRPLNDNQWHNVVIT	NRXN3	946	Q9Y4C0
WQQENKPHVLLFDQT	DNAJC16	266	Q9Y2G8
WLEENVHPSLQRLQA	HEXD	446	Q8WVB3
EDPQIQAHWSNINDV	MED17	456	Q9NVC6
PNQEINFHLLGNLWL	ITGA11	1076	Q9UKX5
LHHIWQSQQRLQPVA	IRF5	461	Q13568
VLLENPSQGNEWSHI	KCNT2	81	Q6UVM3
GAHTALPQLLLQENW	PAPPA	276	Q13219
LPQLLLQENWDNVKH	PAPPA	281	Q13219
HQLNVVIHQLNAPLW	OTUD3	146	Q5T2D3
QDNSPQHKQSWNVLE	PPP1R3A	646	Q16821
QPQRLQWDLPDQIHS	CPT1C	511	Q8TCG5
LQSPFLTQVHSEQWQ	CPT1C	666	Q8TCG5
LNGLAEQLWHQDQVA	CPLANE2	231	Q9BU20
EQLWHQDQVAAGLLP	CPLANE2	236	Q9BU20
HNDQSQWLQVDLLVP	EDIL3	371	O43854
QLQTLDVTQNPWHCD	GP9	76	P14770
DVLLGSSIPWQQLQH	CABIN1	1551	Q9Y6J0
SEHHNQPLWLTRLQD	CACNA1S	451	Q13698
ELNLQNHQPSESNWL	CGNL1	161	Q0VF96
EPWYDHQDLQQDLQL	CDR2	16	Q01850
LEPAQWISILNSNEH	CEP85	321	Q6P2H3
VLSWIPSNNHQLQLA	RAP1GDS1	321	P52306
EALQINQDHPDAWSL	CTR9	556	Q6PD62
WIAHPNNNLINNAAA	CEMIP2	666	Q9UHN6
GHLDPTWALQQLQQL	MAN2B2	396	Q9Y2E5
HLQDCPVTNVQDWNE	MBTPS2	281	O43462
LVVPWQNSSQLLKHN	CST6	131	Q15828
NHLDQNPQLQWNTTE	GABBR2	856	O75899
QLLSWIDLEFNHPQI	KL	396	Q9UEF7
EHAQPLNQWPEQHLD	FIGNL2	6	A6NMB9
ANINLTHQPWFQVLE	B3GNT7	91	Q8NFL0
LPLQDNLEEHQAWLD	CEP295	1251	Q9C0D2
EGLEAWPQLLQLLQH	IPO4	111	Q8TEX9
LLQNQAIEVVWSHQP	PEX1	41	O43933
LVVQSPSLLNDNQWH	CNTNAP5	861	Q8WYK1
QELVIHIGWIISNNP	PHKB	851	Q93100
TNQVVHELNELWPDL	KRBA2	331	Q6ZNG9
LQWQLNLLTHIENVQ	PHF20L1	941	A8MW92
QRLSAAQVLQHPWVQ	MKNK1	361	Q9BUB5
FLLWGLSDQPQQQHI	OR1P1	26	Q8NH06
EQNLQQWHLDLVQLI	MRPS27	376	Q92552
NLQPDHDIQRWLQGL	RGL2	481	O15211
ENSHPVWTQKENQQL	TACC3	91	Q9Y6A5
QHLPAQEQWDRLLVL	PLEKHN1	231	Q494U1
TPLQNNLHELWALLN	SMARCA1	341	P28370
WLQQANVAVEPETLN	SYNE2	4251	Q8WXH0
AAAVELWQHFQRPLQ	SYNE3	436	Q6ZMZ3
HLWNRPLENDSFLQV	FER1L5	51	A0AVI2
VNPHLHLEWNQLQTI	LMBRD2	171	Q68DH5
QERPGVVLQQLQLHW	PLEKHG4	581	Q58EX7
SLLFWPENQQLDQHS	SAMD9	1436	Q5K651
LNAIVQIDLNENPWD	SLITRK3	551	O94933
DIQTLNHLNWLNDEI	SENP1	456	Q9P0U3
LHFLNPQEAQRWAVL	SHARPIN	101	Q9H0F6
NHLLLQNNLPAVRWV	CCT5	311	P48643
QPLENHVALIHWQSA	WT1-AS	6	Q06250
QGPLSIQEEWVRHLQ	WIZ	1606	O95785
RIISHVWENNNPFQI	PIK3CB	321	P42338
ECLNQEHQSLQLPWS	NINL	1206	Q9Y2I6
LEGAWQEHQLQLQQA	SPTBN5	2561	Q9NRC6
VLELAQDNPWVINLH	STK17A	111	Q9UEE5
HILQNPRVWLDAATQ	SLC6A18	246	Q96N87
QWADEHIQSQKLNPF	ABRA	251	Q8N0Z2
QENALWPNLTVRQHL	ABCA8	1366	O94911
NVWQPDAIEVLQQLL	RNF17	1301	Q9BXT8
QLVTQLHWQENGPTF	PREB	226	Q9HCU5
WIQQNLRHILSQPET	RWDD3	106	Q9Y3V2
TQVAVNAHQWLDNPE	SEPHS2	256	Q99611
AHLVNQDDPNVLEIW	AARS1	201	P49588
LLPSEINHLEWNVLQ	SPATA31D1	616	Q6ZQQ2
NNNWVVRHNSKEIPI	MID1	581	O15344
EPAHAQENWLLNSNI	TENM4	231	Q6N022
VLLQEIQIWVRQQHP	SCAND2P	96	Q9GZW5
EWQQLNPAQKTLHRD	ZNF630	21	Q2M218
KQWHSQGLLQAQDPL	ZNF536	1231	O15090
SNLINETLANHPEWA	TMEM245	496	Q9H330
LQEFQNDHQLPWKNL	ZBED6	626	P86452
ILPEELQIWVQQHNP	ZNF397	101	Q8NF99
LQIWVQQHNPESGEE	ZNF397	106	Q8NF99
QTCQQLLLPDDWGQH	ZCCHC4	126	Q9H5U6
QLQPSDRDWVRHQLQ	PHLPP1	186	O60346
WNPHAVVALRNNLEI	TRMT12	266	Q53H54
IQSLNLAWNRLHAVP	TSKU	186	Q8WUA8
TILPEELQAWVQEQH	ZSCAN12	96	O43309
NWHEEVLRQLQQGLA	TRRAP	3331	Q9Y4A5
GLQRVHEPTWAQQLL	TMEM234	31	Q8WY98
PAAELLQDHQLLWAQ	KIAA2013	326	Q8IYS2
QHSWIEQQVLEANPI	MYO7B	181	Q6PIF6
HQWTCLPDQNDVVQA	NEB	2386	P20929