Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessvasoconstriction

DRD1 SHC1 BBS2 KEL MMP2 G6PD

1.01e-05121846GO:0042310
PathwayPID_WNT_CANONICAL_PATHWAY

CUL3 WNT3A PI4K2A DVL3

1.37e-0620604M90
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PLCD3 SH3TC2 TRPM3 EXPH5 DIP2C ZNF407 PCDH18 ATP8B2 SHANK3

3.41e-0649385915368895
Pubmed

Haematological profile of malaria patients with G6PD and PKLR variants (erythrocytic enzymopathies): a cross-sectional study in Thailand.

PKLR G6PD

5.90e-06285236038921
Pubmed

Dvl3 translocates IPMK to the cell membrane in response to Wnt.

WNT3A DVL3

5.90e-06285222940627
Pubmed

Rac1b recruits Dishevelled and β-catenin to Wnt target gene promoters independent of Wnt3A stimulation.

WNT3A DVL3

5.90e-06285221667018
Pubmed

Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation.

TBX10 TBX1

5.90e-06285215703190
Pubmed

Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy.

FAT3 LRP1B

5.90e-06285235069585
Pubmed

G6PD facilitates clear cell renal cell carcinoma invasion by enhancing MMP2 expression through ROS‑MAPK axis pathway.

MMP2 G6PD

5.90e-06285232319593
Pubmed

Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.

WNT3A SHC1

5.90e-06285225147340
Pubmed

The t(11;20)(p15;q11) chromosomal translocation associated with therapy-related myelodysplastic syndrome results in an NUP98-TOP1 fusion.

NUP98 TOP1

5.90e-06285210556215
Pubmed

Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer.

FAT3 LRP1B

5.90e-06285238696842
Pubmed

Wnt-dependent assembly of supermolecular Dishevelled-3-based complexes.

WNT3A DVL3

1.77e-05385220940260
Pubmed

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.

CUL3 DVL3

1.77e-05385216547521
Pubmed

TLR4 induced Wnt3a-Dvl3 restrains the intensity of inflammation and protects against endotoxin-driven organ failure through GSK3β/β-catenin signaling.

WNT3A DVL3

1.77e-05385231884387
Pubmed

Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation.

WNT3A DVL3

1.77e-05385216501258
Pubmed

Genetic localization and phenotypic expression of X-linked cataract (Xcat) in Mus musculus.

EDA G6PD

1.77e-0538522272505
Pubmed

PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2.

CDC25C PML

1.77e-05385212402044
Pubmed

Wingless (Wnt)-3A induces trophoblast migration and matrix metalloproteinase-2 secretion through canonical Wnt signaling and protein kinase B/AKT activation.

WNT3A MMP2

1.77e-05385219887570
Pubmed

Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.

FAM184A ARMC2 PML

1.82e-052185324407287
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

CUL3 PDE4DIP DOCK6 ZBED1 TBL1XR1 PML

1.86e-0522385633187986
Pubmed

A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.

CELF5 ADAM19 MAD1L1 DOCK6

1.89e-056485420889312
Pubmed

Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal.

TCF3 WNT3A

3.53e-05485221685894
Pubmed

Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development.

SHC1 SHC4

3.53e-05485221117147
Pubmed

CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling.

WNT3A CXXC5

3.53e-05485230479059
Pubmed

The T-box gene Tbx10 exhibits a uniquely restricted expression pattern during mouse embryogenesis.

TBX10 TBX1

3.53e-05485212915323
Pubmed

Localization of the region homologous to the Duchenne muscular dystrophy locus on the mouse X chromosome.

EDA G6PD

5.87e-0558523600794
Pubmed

The mapping of a cDNA from the human X-linked Duchenne muscular dystrophy gene to the mouse X chromosome.

EDA G6PD

5.87e-0558523600793
Pubmed

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.

PLK2 CDC25C

5.87e-05585219597481
Pubmed

Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA.

WNT3A DVL3

5.87e-05585221652632
Pubmed

Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled.

WNT3A DVL3

5.87e-05585220137080
Pubmed

The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor.

SHC1 SHC4

5.87e-05585224430869
Pubmed

Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl.

WNT3A DVL3

5.87e-05585220227366
Pubmed

The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses.

CUL3 PML

5.87e-05585220389280
Pubmed

Interaction with the Bardet-Biedl gene product TRIM32/BBS11 modifies the half-life and localization of Glis2/NPHP7.

BBS2 PML

5.87e-05585224500717
Pubmed

Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice.

EDA TBX1

5.87e-05585218848976
Pubmed

KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination.

CUL3 PML

8.80e-05685225619834
Pubmed

Detailed ordering of markers localizing to the Xq26-Xqter region of the human X chromosome by the use of an interspecific Mus spretus mouse cross.

EDA G6PD

8.80e-0568522882509
Pubmed

SUMO-1-dependent allosteric regulation of thymine DNA glycosylase alters subnuclear localization and CBP/p300 recruitment.

TDG PML

8.80e-05685217060459
Pubmed

Functional proteomics mapping of a human signaling pathway.

PLCD3 EXPH5 ZSCAN4 PDE4DIP DVL3 CXXC5 TDG NIBAN2

1.01e-0459185815231748
Pubmed

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

ATN1 FAT3

1.23e-04785222510986
Pubmed

The localization of G6pd, glucose-6-phosphate dehydrogenase, and mdx, muscular dystrophy in the mouse X chromosome.

EDA G6PD

1.23e-0478523243423
Pubmed

Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.

SHC1 SHC4

1.23e-04785228213521
Pubmed

Enzyme-activity mutants in Mus musculus. I. Phenotypic description and genetic characterization of ethylnitrosourea-induced mutations.

PKLR G6PD

1.23e-04785210886019
Pubmed

The physical association and phosphorylation of Cdc25C protein phosphatase by Prk.

PLK2 CDC25C

1.23e-04785210557092
Pubmed

Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate.

EXPH5 PI4K2A

1.23e-04785225940347
Pubmed

Mad1 destabilizes p53 by preventing PML from sequestering MDM2.

MAD1L1 PML

1.23e-04785230948704
Pubmed

Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth.

WNT3A DVL3

1.64e-04885215454084
Pubmed

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6.

WNT3A DVL3

2.10e-04985222899650
Pubmed

Chromosomal localization, hematologic characterization, and iron metabolism of the hereditary erythroblastic anemia (hea) mutant mouse.

PKLR G6PD

2.10e-04985215155459
Pubmed

Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes.

WNT3A DVL3

2.10e-04985223095888
Pubmed

Tcf3 represses Wnt-β-catenin signaling and maintains neural stem cell population during neocortical development.

TCF3 WNT3A

2.10e-04985224832538
Pubmed

Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein.

TDG PML

2.10e-04985215569683
Pubmed

Regulation of the Wnt signaling pathway by disabled-2 (Dab2).

WNT3A DVL3

2.10e-04985212805222
Pubmed

Ubc9 sumoylation regulates SUMO target discrimination.

TDG PML

2.62e-041085218691969
Pubmed

A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression.

CUL3 PML

2.62e-041085221840486
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

POU6F2 TCF3 SH3TC1 MAD1L1 CXXC5 DIP2C ZFHX2 CEP192 DOCK6 ARMC2 TBL1XR1 ITPK1

2.65e-041489851228611215
Pubmed

Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

ANKS6 BBS2 KIF7

2.86e-045285320301743
Pubmed

TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair.

TDG PML

3.20e-041185235061896
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLCD3 ANKS6 SH3TC1 MAD1L1 SHC1 DIP2C CEP192 IL17RD DOCK6 TTC38

3.64e-041105851035748872
Pubmed

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.

DVL3 TBX1

3.83e-04128529774969
Pubmed

LIM-homeobox gene Lhx5 is required for normal development of Cajal-Retzius cells.

EBF2 WNT3A

3.83e-041285220685998
Pubmed

Conservation and reorganization of loci on the mammalian X chromosome: a molecular framework for the identification of homologous subchromosomal regions in man and mouse.

EDA G6PD

3.83e-04128522899541
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CUL3 SEPHS1 PLK2 ADAM19 TRPM3 MMP2 TBL1XR1 LRP1B

4.21e-0473085834857952
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ATN1 MAD1L1 DVL3 SHANK3 GOLGA3 KIF7 PML

4.51e-0456085721653829
Pubmed

The Hippo pathway regulates Wnt/beta-catenin signaling.

WNT3A DVL3

4.52e-041385220412773
Pubmed

Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.

CUL3 DCUN1D4

4.52e-041385223201271
Pubmed

Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.

EBF2 WNT3A

4.52e-041385222421355
Pubmed

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.

SH3TC2 MYH13 SH3TC1 TRPM3 NUP98

4.94e-0426585519240061
Pubmed

TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.

NUP98 NXF3

5.27e-041485211073998
Pubmed

Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135.

DRD1 SHC1

5.27e-041485211409899
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

TCF3 PKLR TBL1XR1 EDA TOP1

5.93e-0427685528319085
Pubmed

Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.

PLCD3 PDE4DIP NUP98 TOP1

5.95e-0415685429961565
Pubmed

The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes.

EBF2 WNT3A

6.07e-041585217928452
Pubmed

Control of neuronal morphology by the atypical cadherin Fat3.

EBF2 FAT3

6.93e-041685221903076
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

MAD1L1 KEL CEP192 DOCK6

8.20e-0417085423314748
Pubmed

Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.

CUL3 DCUN1D4

8.80e-041885226906416
Pubmed

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak.

WNT3A DVL3

8.80e-041885219701191
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

CUL3 SP140L PXDNL IL17RD PML

1.04e-0331385520800603
Pubmed

ETO2 coordinates cellular proliferation and differentiation during erythropoiesis.

TCF3 TOP1

1.09e-032085216407974
Pubmed

Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates.

MYH13 TBX1

1.09e-032085219531352
Pubmed

Ectodysplasin-A signaling is a key integrator in the lacrimal gland-cornea feedback loop.

MMP2 EDA

1.20e-032185231221639
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD PLK2 EXPH5 MAD1L1 CEP192 CDC25C DOCK6 PML

1.23e-0386185836931259
Pubmed

Differences in health status affect susceptibility and mapping of genetic loci for atherosclerosis (fatty streak) in inbred mice.

EBF2 PI4K2A

1.32e-032285222837474
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CELF5 MYH13 EXPH5 ADGRF3 MEI1 G6PD

1.39e-0349785636774506
Pubmed

Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity.

FAM184A PDE4DIP

1.44e-032385222792062
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

MYO1G NUP98 TOP1 GOLGA3 PML

1.50e-0334085529478914
Pubmed

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.

EBF2 PSD SHC1 ARMC2

1.52e-0320185423535732
Pubmed

A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers.

CUL3 TDG

1.57e-032485216620772
Pubmed

Shp2 in myocytes is essential for cardiovascular and neointima development.

MMP2 CDC25C

1.57e-032485231634485
Pubmed

Regulation of planar cell polarity by Smurf ubiquitin ligases.

DVL3 PKLR

1.71e-032585219379695
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

ANKS6 DVL3 KIF7

1.92e-0310085325807483
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TRPM3 CEP192 PCDH18

1.98e-0310185310997877
Pubmed

Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.

TCF3 MMP2

1.99e-032785223824573
Pubmed

Embryonic Steroids Control Developmental Programming of Energy Balance.

PKLR SERPINA6

1.99e-032785234599818
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

DIP2C SHANK3

2.14e-032885231600191
Pubmed

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.

CUL3 ATN1

2.30e-032985228794184
Pubmed

Multimodal Hox5 activity generates motor neuron diversity.

EBF2 POU6F2

2.30e-032985239289460
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

FAM184A TRPM3 ELOVL5 CEP192 ARMC2 DCUN1D4 PMFBP1

2.43e-0375085711230166
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM19 SHC1 DOCK6 PDE7B SHANK3 TBX1

1.40e-061838564d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell10x5'v1-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JCAD PLK2 MMP2 DOCK6 SHANK3 TBX1

2.34e-0620085677ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC2 SH3TC1 SP140L SHC1 FIBCD1 TBX1

2.34e-062008565c638c80661017c85f9390f1b398ac7728c8f001
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal-BMP_responsible_cell|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC2 SH3TC1 SP140L SHC1 FIBCD1 TBX1

2.34e-06200856604a88633d4162337e394155c7346dbdef8b9f5a
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO1G SEPHS1 ATN1 TRPM3 SHC1

1.19e-0515585596c48d835725eac1bc7926f4cddecb67c29b7d7c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU6F2 PLK2 DRD1 FAT3 MMP2

1.66e-05166855d1c61270c7b39bb365020eeafe298a8f88aa887e
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

ADAM19 DOCK6 PDE7B SHANK3 TBX1

2.03e-05173855dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCelldroplet-Heart-4Chambers-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 SH3TC1 UNC45B DOCK6 SHANK3

2.03e-051738559a04271c51fae34f547db3206f9ff5857686e45c
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND01-03-samps / Age Group, Lineage, Cell class and subclass

JCAD TCF3 PLK2 ZNF407 IL17RD

2.09e-05174855cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD PLK2 UNC45B ANKDD1B PCDH18

2.39e-05179855ba38177ffcf3a20f02afeeaaa91bc8eab8d1ac05
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD PLK2 UNC45B ANKDD1B PCDH18

2.39e-05179855d121351b4c3b91108e6c5753d18a44d676f38d4c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL PDE4DIP ADAMTS17

2.45e-051808559e09b3dfe344b5d50520711513d389865d73a861
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

2.45e-05180855eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

2.45e-05180855a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

2.59e-05182855041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

2.66e-0518385531ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

2.73e-05184855e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellCV-Moderate-4|CV / Virus stimulation, Condition and Cluster

FAM184A PLK2 SHC4 PDE7B KIF7

2.73e-0518485590f5b447064743246b09a6c47bf561efafa15e1f
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ADAM19 DOCK6 PDE7B SHANK3 TBX1

2.80e-051858554a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ADAM19 DOCK6 PDE7B SHANK3 TBX1

2.80e-0518585536ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

2.80e-05185855898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SH3TC2 MMP2 IL17RD PCDH18

2.95e-05187855b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

2.95e-0518785585e58a312fc325e4063a2d250666b99b8f99beb6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

2.95e-05187855b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SH3TC2 MMP2 IL17RD PCDH18

2.95e-051878559fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SH3TC2 MMP2 IL17RD PCDH18

2.95e-05187855e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

ADAM19 DOCK6 PDE7B SHANK3 TBX1

3.02e-0518885580910dcbb51990f2baed240f319456c0d3fa2065
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAM19 DOCK6 PDE7B SHANK3 TBX1

3.02e-05188855c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellEndothelial-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

PLCD3 NUP98 DOCK6 ATP8B2 TBX1

3.02e-05188855ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAM19 DOCK6 PDE7B SHANK3 TBX1

3.02e-05188855aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

ADAM19 DOCK6 PDE7B SHANK3 TBX1

3.18e-0519085591bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

3.18e-051908553dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

3.18e-05190855cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

3.26e-05191855963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL ADAMTS17 LRP1B

3.34e-05192855562df5e87038c500dd3a003fe5374cb31946b145
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAM19 TRPM3 FAT3 MMP2 TBX1

3.51e-051948558b81f039f5b25d35a4d5a41b27d4d9360ba22f15
ToppCell10x5'-Liver-Lymphocytic_T_CD4|Liver / Manually curated celltypes from each tissue

FAM184A ADAM19 ELOVL5 EDA ATP8B2

3.78e-051978554891111894b741555f549deec6af8006376d9358
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM19 DOCK6 PDE7B SHANK3 TBX1

3.87e-051988559ab0db78394e730f6866b2db80047149024ad5f6
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM19 DOCK6 PDE7B SHANK3 TBX1

3.87e-05198855b3a020522e064bb61949d38e442f24026e339364
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAM19 TRPM3 FAT3 DEPDC1 TBX1

3.87e-051988557225a6194c52b01c581e58d3cda107c4af96dc4f
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM19 DOCK6 PDE7B SHANK3 TBX1

3.87e-05198855fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM19 DOCK6 PDE7B SHANK3 TBX1

3.87e-05198855e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBF2 FAT3 MMP2 DOCK6 TTC38

3.96e-051998556f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBF2 FAT3 MMP2 DOCK6 TTC38

3.96e-051998551aa99d21bf61b86df4a966dc47634044430aa39f
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CELF5 SH3TC2 TRPM3 FAT3 SHC4

3.96e-051998554e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC1 MEI1 DOCK6 PDE7B PCDH18

4.06e-05200855aafe594c88710f8c53d59667cdac5035e08f5511
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM19 SHC1 DOCK6 SHANK3 TBX1

4.06e-05200855f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADAM19 SHC1 DOCK6 SHANK3 TBX1

4.06e-05200855e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Lymphatic|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ADAM19 SHC1 DOCK6 SHANK3 TBX1

4.06e-052008554ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2|Neuronal / cells hierarchy compared to all cells using T-Statistic

POU6F2 ADAMTS17 EDA LRP1B ITPK1

4.06e-052008556b0235cfbdb70068c43ac71301f4a7b41854929e
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

DRD1 DOCK6 PDE7B FRMD1 PCDH18

4.06e-0520085569edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC1 MEI1 DOCK6 PDE7B PCDH18

4.06e-05200855a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD PLK2 NIBAN2 DOCK6 SHANK3

4.06e-0520085590061284a80d29a4ca6078f578e13d32b8cc80e1
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EBF2 EXPH5 MEI1 PDE7B

8.25e-05120854a6d0406a174d46ce06b41280292931954af88a59
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-6|TCGA-Kidney / Sample_Type by Project: Shred V9

SH3TC2 NXF3 G6PD TBX1

1.19e-0413285479b3443c5cfefa172164625a7b2be469311ba2a8
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Thalamus / BrainAtlas - Mouse McCarroll V32

SH3TC1 UNC45B ANKDD1B TBX1

1.23e-0413385429b0c2c682c6b97823e7d8d8ba1f5114044b30ba
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_E|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FAT3 CXXC5 SHC4 PCDH18

1.30e-0413585435928195cf34f055b353562c96f451aef2344d64
ToppCellCOVID-19-kidney-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAM19 PKLR PDE7B TBX1

1.85e-04148854f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEPHS1 MALRD1 ANKDD1B KEL

2.21e-041558544559e3011514041b65c17ae4ede29da202bce14c
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EXPH5 KEL SERPINA6 FRMD1

2.21e-041558545fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ZSCAN4 DOCK6 SHANK3

2.26e-04156854f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCellsevere_influenza-CD8+_T_naive|World / disease group, cell group and cell class (v2)

FAM184A ANKS6 PSD EDA

2.49e-04160854a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CELF5 DRD1 MEI1 PDE7B

2.55e-04161854ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCellsevere_influenza-CD8+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

FAM184A ANKS6 PSD EDA

2.55e-0416185482196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MALRD1 PKLR KEL CDC25C

2.68e-04163854aa5ea367f787c1543afb7eb80a801432e1c44011
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

MYO1G LRRC66 IL17RD TTC38

2.74e-0416485460fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATN1 DEPDC1 CDC25C LRP1B

2.80e-041658540edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

JCAD MALRD1 FAT3 CDC25C

2.80e-041658547b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DVL3 NIBAN2 G6PD ATP8B2

2.80e-0416585494a5211072464fc24592bb107a853ce832e816fe
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATN1 DEPDC1 CDC25C LRP1B

2.80e-04165854fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|368C / Donor, Lineage, Cell class and subclass (all cells)

JCAD EXPH5 EDA SHANK3

2.87e-0416685430a991fc3275b571d53bd0976df4789e5d40b01d
ToppCellfacs-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC66 SH3TC2 FAT3 KEL

2.87e-041668548d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|368C / Donor, Lineage, Cell class and subclass (all cells)

JCAD EXPH5 EDA SHANK3

2.87e-0416685476b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCellfacs-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC66 SH3TC2 FAT3 KEL

2.87e-04166854f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCellfacs-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC66 SH3TC2 FAT3 KEL

2.87e-04166854a5074c96c6561273029aceb93402a7e038140f50
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PLCD3 JCAD TRPM3 KIF7

2.93e-041678545c82d801e3b7d7c6c967a73b94b2ee2a8da1fd6e
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

ADAM19 PDE7B SHANK3 TBX1

2.93e-0416785497d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

JCAD TRPM3 SHANK3 TBX1

3.00e-041688548c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD SH3TC1 DOCK6 SHANK3

3.21e-04171854b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EBF2 MMP2 PCDH18 ATP8B2

3.28e-04172854e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EBF2 ADAMTS17 LRP1B PMFBP1

3.35e-04173854b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EXPH5 NUP98 MMP2 GOLGA3

3.35e-04173854b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5-6_RORB_LINC00320|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POU6F2 EDA LRP1B ITPK1

3.35e-041738544ec147479b359cce1975d57a50ee1437a0e1e663
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

MYO1G JCAD G6PD TTC38

3.35e-041738541e8a43ff32eab95857c794e0bf4f0b0dba155b4a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH3TC2 TRPM3 CXXC5 SHC4

3.35e-04173854789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 TRPM3 PDE4DIP ZFHX2

3.43e-04174854f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184A MALRD1 PXDNL LRP1B

3.50e-04175854e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

JCAD LRP1B SHANK3 TBX1

3.50e-041758540a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SHC4 DEPDC1 MEI1 CDC25C

3.58e-04176854dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCellwk_20-22-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PKLR KEL DEPDC1 CDC25C

3.58e-0417685498814f0a67411b2f7b25dc489b2aadb77f45a853
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 SHC1 MEI1 TBX1

3.58e-041768548eb91dcf55d4e3e28a72d447181bf6d2ad891fc6
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

SHC1 PDE7B SHANK3 TBX1

3.58e-0417685498c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 DVL3 CXXC5 MEI1

3.58e-04176854606704098bfdf8bfef740a3544a372fae1e75969
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

SHC1 PDE7B SHANK3 TBX1

3.58e-04176854c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ADAM19 EXPH5 NUP98 MMP2

3.58e-04176854437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 DVL3 CXXC5 MEI1

3.58e-04176854acb9e29773030f6452a069f8f7e53eab68ab7bd3
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CAVIN4 SH3TC2 SH3TC1 TBX1

3.66e-0417785476f5df101c693e5fa61554244d877fc8169ee66f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5-6_RORB_LINC00320|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POU6F2 ADAMTS17 EDA LRP1B

3.66e-0417785401df8ab3285fa66b4805c555cfbfc4b3b16db919
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD UNC45B ATP8B2 SHANK3

3.66e-041778548ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EBF2 PXDNL UNC45B PCDH18

3.74e-04178854066dbc4cc2083c549d98122ed44707127f34d582
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A

JCAD DRD1 ATN1 PI4K2A DIP2C EDA PML

7.70e-061928575216_UP
DrugBeta-sistosterol [83-46-5]; Down 200; 9.6uM; PC3; HT_HG-U133A

JCAD SH3TC2 TCF3 ATN1 ZNF407 MMP2 PML

8.52e-061958574073_DN
DrugPanthenol (D) [81-13-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A

ADAM19 ATN1 SP140L DVL3 CDC25C FRMD1 PML

1.00e-052008577455_UP
DrugProchlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A

ATN1 SH3TC1 ZNF407 ATP8B2 ITPK1 PML

6.23e-051828565010_UP
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

DRD1 PI4K2A PKLR KEL CDC25C PMFBP1

8.13e-051918565581_UP
Drug2,3 pg

PKLR G6PD

8.22e-054852CID003081496
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

ADAM19 PDE4DIP PI4K2A CDC25C TTC38 ATP8B2

8.37e-051928566958_UP
DrugTriamcinolone [124-94-7]; Up 200; 10.2uM; PC3; HT_HG-U133A

POU6F2 TCF3 SH3TC1 PDE4DIP PI4K2A ZFHX2

8.61e-051938562078_UP
DrugProgesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A

SH3TC2 TCF3 PDE4DIP PI4K2A TTC38 PML

8.61e-051938566646_DN
DrugColchicine [64-86-8]; Up 200; 10uM; MCF7; HT_HG-U133A

ATN1 PI4K2A DVL3 ZNF407 EDA ATP8B2

8.86e-051948563213_UP
DrugMeclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A

DRD1 SH3TC1 ZFHX2 CDC25C EDA TTC38

8.86e-051948563285_UP
DrugFillalbin [4540-25-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A

TCF3 ATN1 PDE4DIP KEL MMP2 PML

9.37e-051968564172_DN
DrugCyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; PC3; HT_HG-U133A

EBF2 PDE4DIP PI4K2A ELOVL5 EDA ITPK1

9.37e-051968564252_UP
DrugIdoxuridine [54-42-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A

FAM184A TRPM3 PI4K2A CDC25C EDA PML

9.37e-051968564785_UP
Druggenistein; Up 200; 10uM; MCF7; HT_HG-U133A

POU6F2 ATN1 PDE4DIP DVL3 ITPK1 PML

9.37e-051968565232_UP
DrugAmyleine hydrochloride [532-59-2]; Up 200; 14.8uM; PC3; HT_HG-U133A

EBF2 ATN1 KEL EDA PMFBP1 PML

9.37e-051968564089_UP
DrugChenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A

TCF3 DRD1 ATN1 PI4K2A TBX10 ITPK1

9.64e-051978566012_DN
Drug0317956-0000 [391210-11-0]; Down 200; 1uM; PC3; HT_HG-U133A

TCF3 ATN1 PDE4DIP DOCK6 ATP8B2 PML

9.64e-051978563777_DN
DrugMetoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A

DVL3 ELOVL5 MMP2 DOCK6 EDA FRMD1

9.64e-051978563728_DN
DrugTerconazole [67915-31-5]; Down 200; 7.6uM; PC3; HT_HG-U133A

TCF3 SH3TC1 DVL3 ELOVL5 TTC38 PML

9.64e-051978564583_DN
DrugCytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A

TCF3 DVL3 DOCK6 EDA ATP8B2 PML

9.64e-051978562759_UP
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A

SH3TC1 PDE4DIP DVL3 ZFHX2 FRMD1 ATP8B2

9.64e-051978563639_DN
DrugRoxithromycin [80214-83-1]; Up 200; 4.8uM; HL60; HT_HG-U133A

CUL3 POU6F2 PDE4DIP PKLR CDC25C PML

9.64e-051978562992_UP
DrugMimosine [500-44-7]; Up 200; 20.2uM; PC3; HT_HG-U133A

ATN1 PDE4DIP NUP98 CDC25C TBX1 PML

9.64e-051978566703_UP
DrugPronethalol hydrochloride [51-02-5]; Up 200; 15uM; PC3; HT_HG-U133A

EBF2 ATN1 TRPM3 PDE4DIP ZNF407 PDE7B

9.64e-051978563984_UP
DrugHydrochlorothiazide [58-93-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A

TCF3 DRD1 PDE4DIP PI4K2A TBX10 ITPK1

9.91e-051988564970_DN
DrugCefotetan [69712-56-7]; Down 200; 7uM; MCF7; HT_HG-U133A

ATN1 ELOVL5 DOCK6 EDA ITPK1 PML

9.91e-051988564116_DN
DrugTrazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; HL60; HT_HG-U133A

EXPH5 PDE4DIP PI4K2A ZFHX2 DOCK6 PML

9.91e-051988562379_UP
DrugBisoprolol fumarate; Up 200; 9uM; PC3; HT_HG-U133A

EBF2 CUL3 PSD ELOVL5 ZFHX2 EDA

9.91e-051988566748_UP
DrugHydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; PC3; HT_HG-U133A

DRD1 ATN1 PDE4DIP PKLR PMFBP1 PML

9.91e-051988565075_UP
DrugKanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A

ATN1 PDE4DIP GFM1 EDA TBX1 PMFBP1

1.02e-041998565686_UP
DrugArticaine hydrochloride [23964-57-0]; Down 200; 12.4uM; HL60; HT_HG-U133A

CUL3 TCF3 SH3TC1 MMP2 ATP8B2 PMFBP1

1.02e-041998563138_DN
DrugNiflumic acid [4394-00-7]; Up 200; 14.2uM; HL60; HT_HG-U133A

PI4K2A CDC25C DOCK6 EDA PMFBP1 PML

1.02e-041998562399_UP
DrugMethapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; MCF7; HT_HG-U133A

EXPH5 DVL3 DOCK6 EDA ATP8B2 PML

1.02e-041998563205_UP
DrugDioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A

PDE4DIP ZNF407 MMP2 TTC38 PMFBP1 PML

1.02e-041998566478_UP
DrugOxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

CUL3 ATN1 PI4K2A ZNF407 FRMD1 PML

1.02e-041998562266_UP
DrugTropine [120-29-6]; Up 200; 28.4uM; MCF7; HT_HG-U133A

MYH13 PI4K2A ZNF407 KEL CDC25C TBX1

1.02e-041998563569_UP
Diseasecongenital nonspherocytic hemolytic anemia (is_implicated_in)

PKLR G6PD

7.77e-055832DOID:2861 (is_implicated_in)
Diseasemental or behavioural disorder

CELF5 ADAM19 MAD1L1 SHC4 DOCK6

1.54e-04179835EFO_0000677
DiseaseEnzymopathy

PKLR G6PD

4.23e-0411832C0520572
DiseaseSitus Inversus

ANKS6 DNAH9

4.23e-0411832C0037221
Diseaseschizophrenia, intelligence, self reported educational attainment

FAM184A PLK2 FAT3 MAD1L1 LRP1B SHANK3

4.40e-04346836EFO_0004337, EFO_0004784, MONDO_0005090
Disease3-hydroxypropylmercapturic acid measurement

JCAD PLK2 TRPM3 MAD1L1 LRP1B PMFBP1

4.82e-04352836EFO_0007014
Diseaseunipolar depression

EBF2 JCAD MYH13 SP140L TRPM3 MAD1L1 DVL3 PKLR SHC4 MEI1 PMFBP1

5.53e-0412068311EFO_0003761
Diseasemale infertility (implicated_via_orthology)

ARMC2 PMFBP1

5.98e-0413832DOID:12336 (implicated_via_orthology)
Diseasecortisol measurement, response to corticosteroid, response to synacthen

LRP1B PDE7B

5.98e-0413832EFO_0005843, EFO_0009175, GO_0031960
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

TBX10 TBX1

6.96e-0414832DOID:0060413 (implicated_via_orthology)
DiseaseTesticular Germ Cell Tumor

MAD1L1 MMP2

6.96e-0414832C1336708
DiseaseGeneralized hypotonia

ATN1 TRPM3

8.02e-0415832C1858120
DiseaseCardiovascular Abnormalities

ANKS6 ATN1

9.14e-0416832C0243050
Diseaseglaucoma

POU6F2 ELOVL5 LRP1B PDE7B

9.52e-04154834MONDO_0005041
DiseaseBardet-Biedl syndrome 1 (disorder)

BBS2 KIF7

1.03e-0317832C2936862
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

TRPM3 SHC4 LRP1B

1.30e-0376833EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
DiseaseCleft Palate

ATN1 TBX1 KIF7

1.56e-0381833C0008925
DiseaseHeadache, HbA1c measurement

MAD1L1 PML

1.59e-0321832EFO_0004541, HP_0002315
Diseasehyperglycemia (biomarker_via_orthology)

DRD1 PKLR

1.59e-0321832DOID:4195 (biomarker_via_orthology)
Diseaseforced expiratory volume

JCAD POU6F2 ADAM19 ADAMTS17 IL17RD ARMC2 PMFBP1 ITPK1

1.70e-03789838EFO_0004314
DiseaseProstatic Neoplasms

CUL3 MAD1L1 IL17RD ZBED1 TBL1XR1 LRP1B PML

1.76e-03616837C0033578
DiseaseMalignant neoplasm of prostate

CUL3 MAD1L1 IL17RD ZBED1 TBL1XR1 LRP1B PML

1.76e-03616837C0376358
Diseasesquamous cell lung carcinoma, family history of lung cancer

MYO1G ELOVL5 DCUN1D4

1.80e-0385833EFO_0000708, EFO_0006953
Diseasecoronary artery disease

JCAD ADAM19 MALRD1 TRPM3 MAD1L1 EIF2B2 DOCK6 PCDH18 PMFBP1 ITPK1

1.89e-0311948310EFO_0001645
DiseaseHeadache, type 2 diabetes mellitus

EBF2 MAD1L1

1.90e-0323832HP_0002315, MONDO_0005148
Diseasesmoking status measurement, chronic obstructive pulmonary disease

ADAM19 ARMC2 ITPK1

1.98e-0388833EFO_0000341, EFO_0006527
Diseasetraumatic brain injury (biomarker_via_orthology)

DRD1 MMP2

2.07e-0324832DOID:0081292 (biomarker_via_orthology)
Diseasemalaria (is_implicated_in)

PKLR G6PD

2.07e-0324832DOID:12365 (is_implicated_in)
Disease3-hydroxybutyrate measurement

SERPINA6 PMFBP1

2.25e-0325832EFO_0010982
DiseaseIGF-1 measurement

DRD1 NUP98 CDC25C IL17RD DOCK6 KIF7

2.56e-03488836EFO_0004627
Diseasebody fat distribution

PKLR ADAMTS17 CXXC5 ANKDD1B

2.57e-03202834EFO_0004341

Protein segments in the cluster

PeptideGeneStartEntry
SGLSEVQLNHMDDHT

TDG

166

Q13569
MHSDAAAVNFQLNSH

DCUN1D4

1

Q92564
SHGQAALSVSNMSHH

ADGRF3

291

Q8IZF5
DHSENAIGVAATMAH

ADAM19

331

Q9H013
AACTQLHHALEEGNM

ARMC2

291

Q8NEN0
AAHQLQAMHAQSAEL

ATN1

1136

P54259
DGHVLAVSDNMFVHN

EBF2

221

Q9HAK2
VSINNNGAAMFSSHH

DRD1

361

P21728
DLCGNMANLSLHDHD

DVL3

496

Q92997
MANLSLHDHDGSSGA

DVL3

501

Q92997
MEHNGSASNADKIHQ

CAVIN4

1

Q5BKX8
AMLASLRSELNHQHA

FAM184A

816

Q8NB25
TIAHELGHNLGMNHD

ADAMTS17

386

Q8TE56
LGHNLGMNHDDDHSS

ADAMTS17

391

Q8TE56
INGHSLAHALEADME

ATP8B2

776

P98198
AAHEFGHAMGLEHSQ

MMP2

401

P08253
LNSHMNALHLGSQAN

G6PD

121

P11413
MHNSDPNLHLLAEGA

NIBAN2

571

Q96TA1
NHLNDGKHELMDASE

PCDH18

1106

Q9HCL0
MHSSSHQQQDGDAAM

NXF3

41

Q9H4D5
NGSHELENHQIADSM

NUP98

1161

P52948
AHGTNSHEMAIVFNQ

ITPK1

161

Q13572
NISQHGSDMQVSFDH

IL17RD

206

Q8NFM7
ADENHIEFSNMDGSH

LRP1B

3191

Q9NZR2
HSHSAEMEAQLSQAL

MAD1L1

446

Q9Y6D9
LKDHQNGSMAAVNGH

ELOVL5

266

Q9NYP7
HENLEARGMAQAHSL

JCAD

131

Q9P266
STLSENMLGHLAHNK

PDE7B

396

Q9NP56
SSLHFMHADAQNLGA

CSKMT

136

A8MUP2
HNLIGLSNMHDLSSN

DEPDC1

401

Q5TB30
LEMGNAARHTGATHL

KIF7

196

Q2M1P5
SMEANSVSAIHGHNV

EXPH5

511

Q8NEV8
GMNIARLNFSHGSHE

PKLR

111

P30613
VRQHMADLEGHLQSA

GOLGA3

911

Q08378
AASLLANGHDLAAAM

CXXC5

111

Q7LFL8
MSAAQDHIHRNDILG

LRRC66

521

Q68CR7
SSGLQEVHLAGMNHD

CDC25C

101

P30307
QQLQSMGHLADHSMA

MEI1

1221

Q5TIA1
MGHLADHSMAQTLQA

MEI1

1226

Q5TIA1
AQAAAAAHAAQAHRE

PI4K2A

86

Q9BTU6
GAAELQLHMENSHDS

MALRD1

746

Q5VYJ5
AGDHRANEHLALAAM

PXDNL

956

A1KZ92
QHSHGLDDMQLHQLA

FRMD1

481

Q8N878
AALHSDSQDGHQMAL

EDA

121

Q92838
KNHAMSIHAFDLNSD

BBS2

241

Q9BXC9
VHQKLSADMADHSNL

BBS2

606

Q9BXC9
QNMAGKHAELGNHAE

DOCK6

1601

Q96HP0
KHAELGNHAEAAQCM

DOCK6

1606

Q96HP0
GNHAEAAQCMVHAAA

DOCK6

1611

Q96HP0
RQLTLQHHMGSADLN

CUL3

546

Q13618
EAQAAIHALHGSQTM

CELF5

186

Q8N6W0
QHCEQGLSLDSHALM

FAT3

3751

Q8TDW7
SGAAHRLADVMAQTH

DIP2C

186

Q9Y2E4
DITALMAAIQHGHEA

ANKS6

191

Q68DC2
MAHLNHDLYSGDLNE

CEP192

636

Q8TEP8
LSESQGHMAHLVNSV

FIBCD1

186

Q8N539
GMHANLHKALDNFTQ

DNAH9

4021

Q9NYC9
GTMENIAAQALEHIH

EIF2B2

146

P49770
LQDGAHHMVDSNEIS

GFM1

611

Q96RP9
NMSNHHRGLASANVD

SERPINA6

31

P08185
MGNHNENTGEKLHLA

PMFBP1

146

Q8TBY8
ALMLLNTDLHGHNIG

PSD

656

A5PKW4
QGNLLHLAHSQASMS

POU6F2

426

P78424
DSAFGAVHAQMHAAV

PML

251

P29590
AAGLMHTFNAHAATD

SEPHS1

251

P49903
GFTHHCLANLLMDQA

SH3TC1

161

Q8TE82
DVHNQAVAMANLGHL

SH3TC2

871

Q8TF17
LAMQAGNLHLHEDAH

TEX45

106

Q8NA69
ANEMNHLPAHSQSLQ

SP140L

21

Q9H930
NGAHTIANNHTDMME

TBL1XR1

136

Q9BZK7
DGMSALHFATQSNHV

ANKDD1B

166

A6NHY2
IIANHHMQSISFASG

SHC4

281

Q6S5L8
NLLDDNGHIILNSMH

TBX10

176

O75333
QNAAAGALAMLTAAH

UNC45B

821

Q8IWX7
MQLHARGAAHEENSQ

ZFHX2

836

Q9C0A1
QSSDSELMAQQHHAA

SHANK3

1436

Q9BYB0
ELMAQQHHAASAGLA

SHANK3

1441

Q9BYB0
GLAGSTSLMHNHAAL

TCF3

451

P15923
ENHCGLEQQAAMARH

PLCD3

431

Q8N3E9
NSMHSHFILADNGTT

TRPM3

286

Q9HCF6
NAMAHALQSSRHDCD

MYH13

1331

Q9UKX3
ALVHVHMQGQEALFS

ZSCAN4

131

Q8NAM6
FNDAHFLMASLGAHD

TTC38

331

Q5R3I4
HNNEAGRQAIASHMH

WNT3A

186

P56704
SDHTVGVLFNNGAHM

PLK2

521

Q9NYY3
NLLDDNGHIILNSMH

TBX1

221

O43435
ESNLHQHLASAGHMR

ZNF407

1456

Q9C0G0
QHLASAGHMRNEQAS

ZNF407

1461

Q9C0G0
IAGVLVEDSNNHHLM

ZBED1

371

O96006
MSGDHLHNDSQIEAD

TOP1

1

P11387
IIANHHMQSISFASG

SHC1

251

P29353
NFGAAGSIMAHELLH

KEL

571

P23276
THQGAGLNMTVHSAL

MYO1G

231

B0I1T2
EMLHQSQLGQLHSSE

PDE4DIP

316

Q5VU43