Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleocytoplasmic carrier activity

TNPO1 TNPO2 XPO5 KPNA2

8.19e-05321454GO:0140142
GeneOntologyBiologicalProcessregulation of Rab protein signal transduction

DENND3 MADD DENND4B

6.84e-0661463GO:0032483
HumanPhenoIncreased circulating osteocalcin level

ANKH SLC34A1 FAM20A

1.17e-055553HP:0031428
MousePhenohyposulfatemia

SLC26A1 SLC13A1

5.91e-0521082MP:0002853
MousePhenoabnormal circulating sulfate level

SLC26A1 SLC13A1

5.91e-0521082MP:0002851
MousePhenoabnormal urine sulfate level

SLC26A1 SLC13A1

5.91e-0521082MP:0009471
MousePhenoincreased urine sulfate level

SLC26A1 SLC13A1

5.91e-0521082MP:0009472
DomainARM-type_fold

TNPO1 USP34 TNPO2 USP24 TSC2 APOB FRYL PACRGL PELP1 ARVCF XPO5 NBEAL2 NUP188 STAG3 KPNA2

4.36e-0833914115IPR016024
DomainARM-like

TNPO1 TNPO2 TSC2 FRYL PACRGL PELP1 ARVCF XPO5 NBEAL2 STAG3 KPNA2

6.58e-0627014111IPR011989
Domain-

TNPO1 TNPO2 TSC2 FRYL PACRGL ARVCF XPO5 STAG3 KPNA2

4.85e-0522214191.25.10.10
DomainGamma_tubulin

TUBG2 TUBG1

5.66e-0521412IPR002454
DomainBACK

KLHL24 KLHL25 KBTBD4 KLHL30 BTBD7

8.93e-05601415SM00875
DomainBACK

KLHL24 KLHL25 KBTBD4 KLHL30 BTBD7

9.67e-05611415IPR011705
DomainBACK

KLHL24 KLHL25 KBTBD4 KLHL30 BTBD7

9.67e-05611415PF07707
DomainuDENN

DENND3 MADD DENND4B

1.79e-04151413PF03456
DomainDENN

DENND3 MADD DENND4B

2.19e-04161413SM00799
DomainIBN_N

TNPO1 TNPO2 XPO5

2.19e-04161413SM00913
DomainDENN

DENND3 MADD DENND4B

2.19e-04161413PF02141
DomaindDENN

DENND3 MADD DENND4B

2.19e-04161413PF03455
DomainUDENN

DENND3 MADD DENND4B

2.19e-04161413PS50946
DomainDDENN

DENND3 MADD DENND4B

2.19e-04161413PS50947
DomaindDENN

DENND3 MADD DENND4B

2.19e-04161413SM00801
DomaindDENN_dom

DENND3 MADD DENND4B

2.19e-04161413IPR005112
DomainuDENN_dom

DENND3 MADD DENND4B

2.19e-04161413IPR005113
DomainDENN

DENND3 MADD DENND4B

2.19e-04161413PS50211
DomainDENN_dom

DENND3 MADD DENND4B

2.19e-04161413IPR001194
DomainImportin-beta_N

TNPO1 TNPO2 XPO5

2.65e-04171413IPR001494
DomainSOCS

SOCS7 RAB40AL RAB40B

4.37e-04201413SM00253
DomainUbiB_dom

ADCK5 COQ8B

5.58e-0451412IPR004147
DomainABC1

ADCK5 COQ8B

5.58e-0451412PF03109
DomainAAA

DNAH10 LONP2 PEX6 RUVBL2 ABCA7 ASCC3

7.90e-041441416SM00382
DomainAAA+_ATPase

DNAH10 LONP2 PEX6 RUVBL2 ABCA7 ASCC3

7.90e-041441416IPR003593
DomainPLA2_B

PLA2G4E PLA2G4C

1.16e-0371412PF01735
DomainPLA2C

PLA2G4E PLA2G4C

1.16e-0371412PS51210
DomainLysoPLipase_cat_dom

PLA2G4E PLA2G4C

1.16e-0371412IPR002642
DomainCarbohydrate_sulfotransferase

CHST6 CHST2

1.16e-0371412IPR016469
DomainPLAc

PLA2G4E PLA2G4C

1.16e-0371412SM00022
DomainVPS9

VPS9D1 RIN1

1.54e-0381412SM00167
Domain-

WSCD1 DNAH10 LONP2 PEX6 CHST6 DDX56 TEP1 RUVBL2 ABCA7 RAB40AL RAB40B CHST2 ASCC3 ELP4

1.55e-03746141143.40.50.300
DomainArm

TNPO2 ARVCF KPNA2

1.62e-03311413PF00514
DomainBEACH

WDR81 NBEAL2

1.97e-0391412PS50197
DomainBeach

WDR81 NBEAL2

1.97e-0391412PF02138
Domain-

WDR81 NBEAL2

1.97e-03914121.10.1540.10
DomainBeach

WDR81 NBEAL2

1.97e-0391412SM01026
DomainBEACH_dom

WDR81 NBEAL2

1.97e-0391412IPR000409
DomainVPS9

VPS9D1 RIN1

2.45e-03101412PS51205
DomainVPS9

VPS9D1 RIN1

2.45e-03101412PF02204
DomainVPS9

VPS9D1 RIN1

2.45e-03101412IPR003123
DomainSulfotransfer_1

WSCD1 CHST6 CHST2

2.51e-03361413PF00685
DomainSulfotransferase_dom

WSCD1 CHST6 CHST2

2.51e-03361413IPR000863
DomainSOCS_box

SOCS7 RAB40AL RAB40B

2.93e-03381413PF07525
DomainSOCS_box

SOCS7 RAB40AL RAB40B

3.16e-03391413SM00969
DomainSOCS_box

SOCS7 RAB40AL RAB40B

3.16e-03391413IPR001496
DomainSOCS

SOCS7 RAB40AL RAB40B

3.16e-03391413PS50225
DomainBTB

KLHL24 KLHL25 KBTBD4 KLHL30 BTBD7

3.18e-031311415PF00651
DomainBTB-kelch_protein

KLHL24 KLHL25 KLHL30

4.17e-03431413IPR017096
DomainIMPORTIN_B_NT

TNPO1 TNPO2

4.85e-03141412PS50166
DomainuDENN

MADD DENND4B

4.85e-03141412SM00800
DomainP-loop_NTPase

WSCD1 DNAH10 LONP2 PEX6 CHST6 DDX56 TEP1 RUVBL2 ABCA7 RAB40AL RAB40B CHST2 ASCC3 ELP4

4.93e-0384814114IPR027417
DomainArmadillo

TNPO2 ARVCF KPNA2

5.36e-03471413IPR000225
DomainIBN_N

TNPO1 TNPO2

5.57e-03151412PF03810
Domain-

KLHL25 KBTBD4 KLHL30

5.68e-034814132.120.10.80
DomainIntegrin_alpha_C_CS

ITGA3 ITGAD

6.34e-03161412IPR018184
DomainAAA

LONP2 PEX6 RUVBL2

7.11e-03521413PF00004
DomainAcyl_Trfase/lysoPLipase

PLA2G4E PLA2G4C

7.15e-03171412IPR016035
DomainBTB

KLHL24 KLHL25 KBTBD4 KLHL30 BTBD7

7.37e-031601415PS50097
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 TRPM4 SPIRE2 PEX6 DDX56 TSC2 FRYL ITGA3 COMTD1 IDUA TEP1 PLEKHG5 ABCA7 TUBG1 MADD ARHGEF40 KLHL25 RPAP1 SH3TC1 ARVCF BTBD7 NBEAL2 NUP188 DOCK6

4.86e-1111051472435748872
Pubmed

Piezo mechanosensory channels regulate centrosome integrity and mitotic entry.

TUBG2 TUBG1 PIEZO2

2.95e-074147336574677
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

LONP2 ORC3 PEX6 EXOC3 RUVBL2 DENND3 MADD ARHGEF40 RPAP1 ARVCF AP5B1 CARD6 SCRIB LRRC41

7.51e-076501471438777146
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP34 COQ8B PEX6 DDX56 ITGA3 DCAF16 TEP1 PLEKHN1 RUVBL2 ABCA7 TUBG1 ARHGEF40 TCHH SH3TC1 NUP188 SCRIB ASCC3 LRRC41

1.25e-0611161471831753913
Pubmed

The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP.

TUBG2 FUZ TUBG1

1.47e-066147338546045
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TNPO1 NAT14 USP24 TSC2 SAMHD1 DCAF16 TUBG1 LRRC47 ARHGEF40 RPAP1 XPO5 NUP188 SCRIB ASCC3 MAP3K7 KPNA2

2.64e-069421471631073040
Pubmed

Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.

CA9 TNPO1 XPO5 KPNA2

4.26e-0626147423181366
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

TRPM4 NAT14 WDR81 COMTD1 PLEKHN1 MADD RIN1 XPO5 FDXR FGA LRPAP1 SCRIB MAP4K2

1.25e-057191471335337019
Pubmed

Influenza virus infection activates TAK1 to suppress RIPK3-independent apoptosis and RIPK1-dependent necroptosis.

RIPK3 MAP3K7

1.77e-052147239044278
Pubmed

MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.

TUBG2 TUBG1

1.77e-052147217442887
Pubmed

Overexpression of γ-tubulin in non-small cell lung cancer.

TUBG2 TUBG1

1.77e-052147222806905
Pubmed

Scribble scrambles parathyroid hormone receptor interactions to regulate phosphate and vitamin D homeostasis.

SLC34A1 SCRIB

1.77e-052147237252981
Pubmed

Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2).

MAP3K7 MAP4K2

1.77e-052147225075558
Pubmed

Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.

TUBG2 TUBG1

1.77e-052147217287496
Pubmed

From Genotype to Phenotype: Nonsense Variants in SLC13A1 Are Associated with Decreased Serum Sulfate and Increased Serum Aminotransferases.

SLC26A1 SLC13A1

1.77e-052147227412988
Pubmed

Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.

TNPO1 TNPO2

1.77e-05214729298975
Pubmed

Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models.

RIPK3 MAP3K7

1.77e-052147236912451
Pubmed

Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.

TUBG2 TUBG1

1.77e-052147228119396
Pubmed

Transportin-1 and Transportin-2: protein nuclear import and beyond.

TNPO1 TNPO2

1.77e-052147224780099
Pubmed

The clinical importance of serum urokinase plasminogen activator receptor and carbonic anhydrase IX levels and the effect of anthracycline-based adjuvant chemotherapy on these biomarkers in breast cancer.

CA9 PLAUR

1.77e-052147229893327
Pubmed

Diagnostic and prognostic significance of CA IX and suPAR in gastric cancer.

CA9 PLAUR

1.77e-052147223512428
Pubmed

Gene knockout analysis of two gamma-tubulin isoforms in mice.

TUBG2 TUBG1

1.77e-052147215893303
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

TNPO1 USP24 SAMHD1 RUVBL2 TUBG1 LRRC47 PELP1 XPO5 NUP188 SCRIB ASCC3 KPNA2

1.85e-056381471233239621
Pubmed

The SOCS box: a tale of destruction and degradation.

SOCS7 RAB40AL RAB40B LRRC41

2.75e-0541147412076535
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

TRPM4 TRPM7 SLCO2B1 EXOC3 APOB ITGA3 PLEKHN1 PIEZO2 ARVCF NBEAL2 SCRIB

3.26e-055691471130639242
Pubmed

Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes.

REC8 STAG3

5.31e-053147224992337
Pubmed

Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.

RIPK3 MAP3K7

5.31e-053147217114179
Pubmed

RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1.

TNPO1 XPO5

5.31e-053147219124606
Pubmed

RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death.

RIPK3 TSC2

5.31e-053147227984090
Pubmed

Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins.

TNPO1 KPNA2

5.31e-05314727604027
Pubmed

Nuclear import of SAMHD1 is mediated by a classical karyopherin α/β1 dependent pathway and confers sensitivity to VpxMAC induced ubiquitination and proteasomal degradation.

SAMHD1 KPNA2

5.31e-053147224712655
Pubmed

Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways.

TNPO1 KPNA2

5.31e-053147212551970
Pubmed

TAK1 regulates endothelial cell necroptosis and tumor metastasis.

RIPK3 MAP3K7

5.31e-053147230683914
Pubmed

The gamma-tubulin gene family in humans.

TUBG2 TUBG1

5.31e-053147210903841
Pubmed

Functional relevance of urinary-type plasminogen activator receptor-alpha3beta1 integrin association in proteinase regulatory pathways.

ITGA3 PLAUR

5.31e-053147216510444
Pubmed

Prediction of the metabolic syndrome status based on dietary and genetic parameters, using Random Forest.

ACACB APOB

5.31e-053147219034549
Pubmed

The stem region of the sulfotransferase GlcNAc6ST-1 is a determinant of substrate specificity.

CHST6 CHST2

5.31e-053147215220337
Pubmed

Human TUBG2 gene is expressed as two splice variant mRNA and involved in cell growth.

TUBG2 TUBG1

5.31e-053147227015882
Pubmed

Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.

TUBG2 TUBG1

5.31e-05314729566969
Pubmed

RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation.

RIPK3 MAP3K7

5.31e-053147223972991
Pubmed

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.

TNPO1 TNPO2

5.31e-053147220606625
Pubmed

The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage.

TUBG2 TUBG1

5.31e-053147226021315
Pubmed

Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing.

RIPK3 MAP3K7

5.31e-053147230975711
Pubmed

Human corneal GlcNac 6-O-sulfotransferase and mouse intestinal GlcNac 6-O-sulfotransferase both produce keratan sulfate.

CHST6 CHST2

5.31e-053147211278593
Pubmed

Intraperitoneal administration of recombinant receptor-associated protein causes phosphaturia via an alteration in subcellular distribution of the renal sodium phosphate co-transporter.

SLC34A1 LRPAP1

5.31e-053147215976002
Pubmed

Involvement of transportin 2-mediated HuR import in muscle cell differentiation.

TNPO1 TNPO2

5.31e-053147217475777
Pubmed

Impaired PTH-induced endocytotic down-regulation of the renal type IIa Na+/Pi-cotransporter in RAP-deficient mice with reduced megalin expression.

SLC34A1 LRPAP1

5.31e-053147212748857
Pubmed

Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.

USP24 APOB DOCK6

5.76e-0518147323726366
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SORBS2 MADD RPAP1 XPO5 BTBD7 DENND4B HERC3 SCRIB BAIAP3

6.27e-05407147912693553
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TNPO2 COQ8B TSC2 SAMHD1 LRRC47 RPAP1 DENND4B PCIF1 PITPNM3 NUP188 SCRIB ELP4

7.34e-057361471229676528
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

SORBS2 ORC3 FN3KRP DDX56 SAMHD1 PLEKHN1 RUVBL2 KLHL25 ELN ASCC3 BAIAP3 ELP4

8.77e-057501471211230166
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

DCPS TSC2 LRRC47 LIG1 SCRIB

9.06e-05106147531024071
Pubmed

Vangl2-regulated polarisation of second heart field-derived cells is required for outflow tract lengthening during cardiac development.

TUBG2 TUBG1 SCRIB

9.30e-0521147325521757
Pubmed

Two sides of MGP null arterial disease: chondrogenic lesions dependent on transglutaminase 2 and elastin fragmentation associated with induction of adipsin.

CFD ELN

1.06e-044147224036114
Pubmed

Cilia organize ependymal planar polarity.

TUBG2 TUBG1

1.06e-044147220164345
Pubmed

The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import.

TNPO1 TNPO2

1.06e-044147210875935
Pubmed

Targeting of nonexpressed genes in embryonic stem cells via homologous recombination.

DDX56 CFD

1.06e-04414722506639
Pubmed

Association of genetic polymorphisms in the fibrinogen and platelet glycoprotein genes with unstable angina in Chinese patients.

ITGA3 FGA

1.06e-044147215346842
Pubmed

Genetic Interactions Between the Meiosis-Specific Cohesin Components, STAG3, REC8, and RAD21L.

REC8 STAG3

1.06e-044147227172213
Pubmed

Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke.

RIPK3 MAP3K7

1.06e-044147232071228
Pubmed

Studying meiotic cohesin in somatic cells reveals that Rec8-containing cohesin requires Stag3 to function and is regulated by Wapl and sororin.

REC8 STAG3

1.06e-044147229724914
Pubmed

Loss of Necdin impairs myosin activation and delays cell polarization.

TUBG2 TUBG1

1.06e-044147220665884
Pubmed

The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals.

TNPO1 KPNA2

1.06e-04414729891055
Pubmed

Karyopherin beta 2B participates in mRNA export from the nucleus.

TNPO1 TNPO2

1.06e-044147212384575
Pubmed

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion.

SLC26A1 SLC13A1

1.06e-044147228192541
Pubmed

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells.

TUBG2 TUBG1

1.06e-044147216798874
Pubmed

Use of denaturing HPLC to map human and murine genes and to validate single-nucleotide polymorphisms.

ABCA7 CFD

1.06e-044147210769753
Pubmed

The l2 minor capsid protein of human papillomavirus type 16 interacts with a network of nuclear import receptors.

TNPO1 KPNA2

1.06e-044147215507604
Pubmed

Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR.

TNPO1 TNPO2

1.06e-044147215037768
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TNPO1 USP34 USP24 DDX56 FRYL LRRC47 PELP1 XPO5 NUP188 ASCC3 STOML2

1.11e-046531471122586326
Pubmed

A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders.

KLHL24 KLHL25 KBTBD4

1.23e-0423147333130828
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

TNPO1 USP34 DCPS USP24 ZC3HC1 FRYL SAMHD1 SMOC1 TYMP RUVBL2 TUBG1 LRRC47 LIG1 XPO5 NUP188 ELP4 KPNA2

1.48e-0414551471722863883
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

TNPO1 LRRC47 XPO5 MAP3K7 KPNA2

1.56e-04119147535776542
Pubmed

Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium.

TUBG2 TUBG1

1.76e-045147221285373
Pubmed

Prdm9 and Meiotic Cohesin Proteins Cooperatively Promote DNA Double-Strand Break Formation in Mammalian Spermatocytes.

REC8 STAG3

1.76e-045147230853435
Pubmed

Analysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and disease.

TUBG2 TUBG1

1.76e-045147219251731
Pubmed

The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis.

TUBG2 TUBG1

1.76e-045147221529752
Pubmed

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis.

TUBG2 TUBG1

1.76e-045147218729223
Pubmed

WDR62 is associated with the spindle pole and is mutated in human microcephaly.

TUBG2 TUBG1

1.76e-045147220890279
Pubmed

Speriolin is a novel human and mouse sperm centrosome protein.

TUBG2 TUBG1

1.76e-045147220542897
Pubmed

Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies.

TUBG2 TUBG1

1.76e-045147225877302
Pubmed

Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation.

TUBG2 TUBG1

1.76e-045147229244804
Pubmed

Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia.

TUBG2 TUBG1

1.76e-045147231390572
Pubmed

STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis.

REC8 STAG3

1.76e-045147212034751
Pubmed

A two-kinesin mechanism controls neurogenesis in the developing brain.

TUBG2 TUBG1

1.76e-045147238040957
Pubmed

Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases.

TUBG2 TUBG1

1.76e-045147216751367
Pubmed

A maternal store of macroH2A is removed from pronuclei prior to onset of somatic macroH2A expression in preimplantation embryos.

TUBG2 TUBG1

1.76e-045147215680357
Pubmed

AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.

TNPO1 KPNA2

1.76e-045147215342649
Pubmed

The host antiviral protein SAMHD1 suppresses NF-κB activation by interacting with the IKK complex during inflammatory responses and viral infection.

SAMHD1 MAP3K7

1.76e-045147237100289
Pubmed

Intranuclear binding by the HIV-1 regulatory protein VPR is dependent on cytosolic factors.

TNPO1 KPNA2

1.76e-045147210772949
Pubmed

GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain.

CHST6 CHST2

1.76e-045147230867513
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40AL RAB40B

1.76e-045147227909076
Pubmed

Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways.

TNPO1 KPNA2

1.76e-04514729817747
Pubmed

Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.

RIPK3 MAP3K7

1.76e-045147230361383
Pubmed

HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes.

TUBG2 TUBG1

1.76e-045147214767062
Pubmed

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.

RIPK3 MAP3K7

1.76e-045147228842570
Pubmed

Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta.

TNPO1 KPNA2

1.76e-04514729405152
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TNPO1 ORC3 USP24 ZC3HC1 RUVBL2 TUBG1 LRRC47 XPO5 SCRIB KPNA2

1.95e-045821471020467437
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

TNPO1 USP34 USP24 TUBG1 PELP1 XPO5 ASCC3

2.07e-04282147723667531
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

SAMHD1 RUVBL2 LRRC47 LIG1 RPAP1 FDXR NUP188 SCRIB ASCC3 TBC1D23 STOML2

2.13e-047041471129955894
InteractionTOP3B interactions

USP34 TRPM4 SPIRE2 PEX6 DDX56 TSC2 APOB FRYL ITGA3 COMTD1 IDUA TEP1 PLEKHG5 ABCA7 TUBG1 MADD ARHGEF40 KLHL25 RPAP1 PELP1 SH3TC1 ARVCF XPO5 BTBD7 NBEAL2 NUP188 DOCK6

3.69e-06147014227int:TOP3B
Cytoband16q24

SPIRE2 CDK10 VPS9D1

2.12e-0517147316q24
Cytoband4p15.31

DCAF16 PACRGL

4.51e-041014724p15.31
GeneFamilyArmadillo repeat containing|Importins

TNPO1 TNPO2 KPNA2

1.54e-04181073596
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND3 MADD DENND4B

4.22e-04251073504
GeneFamilyCohesin complex

REC8 STAG3

9.49e-04810721060
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL24 KLHL25 KBTBD4 KLHL30 BTBD7

1.21e-031341075861
GeneFamilyWD repeat domain containing|BEACH domain containing

WDR81 NBEAL2

1.22e-03910721230
GeneFamilyVPS9 domain containing

VPS9D1 RIN1

1.51e-03101072928
GeneFamilyKelch like|BTB domain containing

KLHL24 KLHL25 KLHL30

1.96e-03421073617
GeneFamilyAAA ATPases

LONP2 PEX6 RUVBL2

3.81e-03531073413
GeneFamilyDNA helicases

RUVBL2 ASCC3

4.45e-031710721167
GeneFamilyCD molecules|Integrin alpha subunits

ITGA3 ITGAD

4.99e-031810721160
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 RENBP TYMP ABCA7 DENND3 CFD TCHH PLAUR

1.49e-0717914783d3716078afdb9a89ddfadb3197cd1b52fa770be
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCK5 SMOC1 VWCE SLC26A1 SERPINA11 PTPRD AFM

2.50e-061821477770ce9f3f4538d0181a0181543841bc964c68274
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCK5 SMOC1 VWCE SLC26A1 SERPINA11 PTPRD AFM

2.50e-06182147777ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCK5 SMOC1 VWCE SLC26A1 SERPINA11 PTPRD AFM

2.50e-0618214774921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 ADCK5 SMOC1 SLC26A1 SERPINA11 PTPRD AFM

2.59e-061831477d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellwk_08-11-Hematologic-Myeloid-APOE+_Mac2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SLCO2B1 SAMHD1 RENBP ITGAD TYMP CFD TCHH

2.78e-0618514778f843badc0e26cb7300c83db56c7974beb90fcf3
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ADAMTS19 TGFBR3 CFD PTPRD SCN7A ELN MUSK

3.32e-06190147712992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLCO2B1 SAMHD1 TYMP DENND3 CFD PLAUR FAM20A

4.21e-06197147767bf15ee83938bd40f6ecd5abaaf90ad95096d21
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 SMOC1 SLC26A1 SERPINA11 PTPRD AFM

1.33e-051561476e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR81 APOB RENBP SLC26A1 SLC13A1 SLC34A1

2.72e-0517714769c7c6824b9011363851f084a500d665f025b026e
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR81 APOB RENBP SLC26A1 SLC13A1 SLC34A1

2.72e-0517714762bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLCO2B1 SAMHD1 RENBP TYMP CFD LRPAP1

2.81e-0517814760b398656f26c4061b11ccf98908d0e2e1367585a
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

ADAMTS19 TGFBR3 CFD SCN7A ELN MUSK

2.90e-051791476dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RGPD2 HLF RENBP PLEKHN1 MADD CHST2

3.18e-05182147621744c9c792e57d5d41b25986f419b2358c7057b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO2B1 SMOC1 PIEZO2 ELN MAP4K2 CCDC136

3.18e-05182147641b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO2B1 SMOC1 PIEZO2 ELN MAP4K2 CCDC136

3.18e-0518214765e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO2B1 SMOC1 PIEZO2 ELN MAP4K2 CCDC136

3.18e-051821476b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLF APOB PTPRD SLC13A1 ARVCF SLC34A1

3.38e-051841476c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLF APOB PTPRD SLC13A1 ARVCF SLC34A1

3.38e-0518414767c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 CFD PTPRD PLAUR TDRD6 FAM20A

3.59e-051861476f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 CFD PTPRD PLAUR TDRD6 FAM20A

3.59e-0518614768694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REC8 DNAH10 RUVBL2 TUBG1 GPR83 BAIAP3

3.70e-051871476269145d71576cbe8fa217090c8aac82d915dbc04
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REC8 DNAH10 RUVBL2 TUBG1 GPR83 BAIAP3

3.70e-0518714767a50aded3243bef2075fb3ec550939ce0694919a
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLCO2B1 AFF3 RENBP PLEKHG5 ANKH GAB3

3.70e-05187147639b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REC8 DNAH10 RUVBL2 TUBG1 GPR83 BAIAP3

3.70e-051871476629b3e05840eb10e598b8dfaabd92ebe02f9995a
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLCO2B1 PLEKHG5 DENND3 SH3TC1 PLAUR FAM20A

3.81e-051881476cb091912f9b627a78a8793a37df7f1de839f887f
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF3 ITGA3 PIEZO2 SH3TC1 SCN7A CHST2

3.93e-05189147609dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 NAT14 ADCK5 HLF SMOC1 CCDC136

3.93e-0518914764dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 NAT14 ADCK5 HLF SMOC1 CCDC136

3.93e-0518914760d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

TGFBR3 CFD PTPRD SCN7A ELN MUSK

4.16e-05191147670c067c54084bfb02c29bab085f4defd477194fb
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CA9 REC8 SORBS2 ITGA3 PLEKHN1 SCN7A

4.29e-0519214762f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

SAMHD1 TGFBR3 CFD SCN7A ELN MUSK

4.29e-051921476356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

ADAMTS19 TGFBR3 CFD SCN7A ELN MUSK

4.41e-051931476dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

SAMHD1 TGFBR3 CFD SCN7A ELN MUSK

4.54e-05194147611c79a8c56ece42713b04b321982e41e239f07a5
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

TGFBR3 CFD PTPRD SCN7A ELN MUSK

4.67e-051951476ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AFF3 ITGA3 PIEZO2 SCN7A PLAUR CHST2

4.67e-0519514767e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFD PIEZO2 PTPRD SCN7A ELN MUSK

4.81e-0519614769737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFD PIEZO2 PTPRD SCN7A ELN MUSK

4.81e-051961476cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFD PIEZO2 PTPRD SCN7A ELN MUSK

4.95e-05197147694a9603cbd3516fbcce871909693b88f20d41713
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFD PIEZO2 PTPRD SCN7A ELN MUSK

4.95e-05197147613896ec65ccda0b928c91d41112dc01b480036b7
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 RENBP TYMP CFD PLAUR FAM20A

5.09e-051981476eb0a94c426a7c567f94490b848e28784587c6dcd
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLCO2B1 SAMHD1 TYMP DENND3 SH3TC1 PLAUR

5.23e-051991476f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCellCOVID-19-Myeloid-MoAM3,_VCAN|COVID-19 / Condition, Lineage and Cell class

SLCO2B1 SAMHD1 TYMP CFD LRPAP1 PLAUR

5.23e-051991476aba0b833e44fe42625fac91466f6ebaa8e786d3b
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLCO2B1 SAMHD1 TYMP DENND3 SH3TC1 PLAUR

5.23e-0519914765ceeed92f831d068ff4bb3994f420002338330e7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 ITGAD CFD DENND4B PLAUR FAM20A

5.23e-051991476667b8b47a5b388506e3177b46747267fad8024f6
ToppCellwk_20-22-Mesenchymal-Fibroblast-Alveolar_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFD PIEZO2 PTPRD SCN7A ELN CHST2

5.38e-0520014760ed49c2177b58269ff7653db6be7d68633a5d34a
ToppCellwk_20-22-Mesenchymal-Fibroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFD PIEZO2 PTPRD SCN7A ELN CHST2

5.38e-05200147694bd00fb6ff0dcb668eb36ec2085f1c3128855b6
ToppCellControl-Myeloid|Control / Condition, Lineage and Cell class

SLCO2B1 SAMHD1 TYMP CFD LRPAP1 PLAUR

5.38e-052001476379f5de322beb7f8f8a58c1609c8f895f8285132
ToppCellwk_15-18-Mesenchymal-Fibroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFD PIEZO2 PTPRD SCN7A ELN CHST2

5.38e-0520014764f624c3c57d1a84baa86d0830cb1b83ae110bf67
ToppCellBiopsy_Other_PF-Immune-Macrophages|Biopsy_Other_PF / Sample group, Lineage and Cell type

SLCO2B1 SAMHD1 RENBP TYMP CFD PLAUR

5.38e-0520014769ff5f0371aac2ab528b581fe979a1522579b8b84
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TYMP SH3TC1 AP5B1 GAB3 PLAUR FAM20A

5.38e-05200147674ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCellTCGA-Uvea|World / Sample_Type by Project: Shred V9

WDR81 EXOC3 RENBP KLHL30 AP5B1

1.05e-041411475015451a83087f2705d3315ebc8f23797c6f10ed6
ToppCelldroplet-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 APOB ITGAD CFD FGA

1.20e-041451475f142b86d4da5b71c189da46cbc4beebdc387ffee
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAT14 CHADL COMTD1 TGFBR3 FDXR

1.45e-041511475def98dc2a8226295b62de2b7f1b587e03a4f038c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PUS3 COMTD1 PLA2G4E KBTBD4 CCDC136

1.54e-0415314750727dc70e16345645063c586d744bc4ac1710526
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Hist1h2al))|Striatum / BrainAtlas - Mouse McCarroll V32

ADAMTS19 APOB PLA2G4C KPNA2

1.57e-048214743cee9ee752128dd91e9abc05c9f97b17e64a2a76
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Opalin_(Opalin)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ITGAD PDILT PLAUR MUSK

1.57e-048214745cd8e47edb775eabf3e9a407c1c2d8a78afb9509
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ITGAD PDILT PLAUR MUSK

1.57e-048214741eeb259ec555879ee1962b7bc2c31c200fbb85cf
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A7 SLC13A1 SLC34A1 AFM SLC4A9

1.59e-04154147589a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A7 SLC13A1 SLC34A1 AFM SLC4A9

1.59e-041541475f1fea1a87e977221fa125b62287368be9af4987d
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A1 SCN7A ELN CHST2 MUSK

1.59e-04154147537765512dfae557b9f6eb30a29463b93682a4404
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A7 SLC13A1 SLC34A1 AFM SLC4A9

1.59e-041541475b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A7 SLC13A1 SLC34A1 AFM SLC4A9

1.59e-041541475160b170a3ade8b246843c9854af332475c047ba0
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

ACACB HLF AFF3 CFD SCN7A

1.90e-0416014758a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

ACACB HLF AFF3 CFD SCN7A

1.90e-041601475d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

ACACB HLF AFF3 CFD SCN7A

1.90e-041601475c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 ACACB SLC34A1 SMIM38 CHST2

1.96e-041611475b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 ACACB SLC34A1 SMIM38 CHST2

1.96e-041611475f7a89c481f789f624102857be722c95fbeb47595
ToppCellBronchial_Brush-Epithelial-Goblet_2|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CA9 TRPM4 VPS9D1 CHST2 FAM20A

2.25e-0416614758ac0a769be886d16642e7e6334471ebadd1a426b
ToppCellBronchial_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CA9 TRPM4 VPS9D1 CHST2 FAM20A

2.32e-041671475806d1c00c137da0c5f042adf866873eb6dd4bb27
ToppCellfacs-Trachea-nan-18m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBG2 PRSS38 CHADL IDUA PIEZO2

2.32e-0416714757b1fd19946cee67dae68f0f0d98420abcd532482
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 ITGA3 TGFBR3 PTPRD SCN7A

2.38e-041681475fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A7 PTPRD SLC13A1 SLC34A1 AFM

2.38e-041681475fa0d251693935116adf633d02b7ec4a295100865
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC8 TRPM4 PUS3 TRPM7 RIN1

2.38e-041681475de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

SAMHD1 CFD SCN7A ELN MUSK

2.45e-0416914756373562ab3b1765060212a6a53d6543e7e942e80
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACB ITGAD GPR83 ZSCAN10 BAIAP3

2.58e-0417114756f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A7 PTPRD SLC13A1 SLC34A1 AFM

2.58e-041711475f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACB ITGAD GPR83 ZSCAN10 BAIAP3

2.58e-041711475ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

REC8 TSC2 ITGA3 IDUA RAB40B

2.58e-0417114753d26ef58fe5231373d7df9ac79d225546918cf82
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT18 TUBG2 SLCO2B1 SDHAF3 FGA

2.66e-041721475b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT18 TUBG2 SLCO2B1 SDHAF3 FGA

2.66e-0417214752f1673fcb2356684d60871debb0f159aec553a1c
ToppCellfacs-Marrow-KLS-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP40 TUBG2 ZSCAN10 CHID1 CHST2

2.73e-041731475295bfe1efa648173c2d5981025bc61c576baf53f
ToppCelldroplet-Heart-4Chambers-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSCD1 SMOC1 DENND3 SH3TC1 DOCK6

2.73e-0417314759a04271c51fae34f547db3206f9ff5857686e45c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A7 PTPRD SLC13A1 SLC34A1 AFM

2.73e-0417314758888434641ea554a9b62c436e87920378eef29cd
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC8 RFX6 FRYL ITGAD PITPNM3

2.80e-041741475f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCelldroplet-Heart-nan-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 AFF3 SMOC1 TGFBR3 CFD

2.80e-041741475cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RFX6 CRH SLC22A7 AP5B1 BAIAP3

2.80e-0417414753503c7dec498597f76a86dbd5e4bb2311e743bde
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 ADCK5 SH3TC1 CARD6 PLAUR

2.95e-041761475d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBG2 SLCO2B1 DENND3 LRRC9 CFD

2.95e-04176147527e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCelldroplet-Kidney-nan-21m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB SLC22A7 ARVCF SLC34A1 LRPAP1

2.95e-0417614750475db3f860de1e216cbdeb886f7a75b9f4fc801
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 ADCK5 SH3TC1 CARD6 PLAUR

2.95e-0417614754f37854124d77ee64dcb40fd491eaed2ba389891
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 ADCK5 SH3TC1 CARD6 PLAUR

2.95e-0417614750afba8707b847e5bdf6f38fe4379967631fe2240
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SAMHD1 LRRC9 SH3TC1 CHST2 SLC4A9

2.95e-0417614756c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

APOB SLC22A7 SERPINA11 AFM FGA

2.95e-041761475b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 TYMP CFD PLAUR FAM20A

3.03e-041771475382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 TYMP ARHGEF40 PLAUR MIEF2

3.11e-041781475c90e9048fc786ba8559972ae25c25ecab4bc1b7c
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 TYMP ARHGEF40 PLAUR MIEF2

3.11e-0417814759e426ce23a4a33b91d139ad85685cf8483bcd01a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WSCD1 SMOC1 PLA2G4C SH3TC1 MAP4K2

3.19e-041791475abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WSCD1 SMOC1 PLA2G4C SH3TC1 MAP4K2

3.19e-0417914750b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RFX6 SMOC1 ARVCF BAIAP3 SLC4A9

3.19e-041791475f2e8fc975c30992611630197b79daaeef7c4211d
ComputationalGenes in the cancer module 245.

TNPO1 TNPO2 LRPAP1 KPNA2

3.23e-0526774MODULE_245
Drugclozapine; Down 200; 10uM; MCF7; HT_HG-U133A

NUDT18 WSCD1 TRPM4 KLHL24 ABCA7 PIGQ VPS9D1 RIN1 PLAUR

4.98e-0619714595589_DN
DrugCP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A

NUDT18 WSCD1 ACACB RIN1 KLHL25 PLA2G4C ARVCF HERC3 BAIAP3

5.19e-0619814594383_UP
DrugSulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A

CA9 NUDT18 HLF SLC22A7 KLHL25 PLA2G4C SH3TC1 BTBD7 MAP4K2

5.41e-0619914592882_UP
Diseasephosphatidylcholine 32:0 measurement

ZC3HC1 PTPRD MUSK

1.79e-05111433EFO_0010372
Diseaseintellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)

TNPO1 TNPO2

2.33e-0521432DOID:0081262 (implicated_via_orthology)
Diseasecomplex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)

TUBG2 TUBG1

2.33e-0521432DOID:0090138 (implicated_via_orthology)
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ACACB DNAH10 USP24 DDX56 APOB PCIF1 PLAUR DOCK6

9.15e-052911438EFO_0008317, EFO_0020946
Diseaseobsolete_red blood cell distribution width

TNPO1 KLHL24 ZC3HC1 APOB SAMHD1 SMOC1 ITGAD TYMP PLEKHG5 ABCA7 LRRC47 PIGQ SLC34A1 PCIF1 PLAUR CHST2 DOCK6 MUSK

9.47e-05134714318EFO_0005192
Diseasefree cholesterol to total lipids in small HDL percentage

APOB MADD PCIF1 MUSK

1.11e-04511434EFO_0022285
Diseasephospholipids:total lipids ratio

USP24 APOB MADD SLC34A1 PCIF1 DOCK6 MUSK

1.25e-042271437EFO_0020946
Diseasefree cholesterol to total lipids in very large HDL percentage

MADD PCIF1 DOCK6 MUSK

1.49e-04551434EFO_0022288
Diseasesuntan

SPIRE2 SAMHD1 VPS9D1 PIEZO2 SMIM38

1.49e-041031435EFO_0004279
Diseaseage at menarche

WSCD1 USP34 ARHGAP40 HLF AFF3 ZC3HC1 MADD GPR83 PTPRD PDILT ASCC3

1.58e-0459414311EFO_0004703
Diseasetriglycerides in large VLDL measurement

DNAH10 APOB PCIF1 MUSK

1.60e-04561434EFO_0022178
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

USP24 APOB MUSK

1.60e-04221433EFO_0009312
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

ACACB DNAH10 APOB PCIF1 MAP4K2 MUSK

1.64e-041661436EFO_0004530, EFO_0004611
Diseasehigh density lipoprotein particle size measurement

DNAH10 APOB MADD PCIF1 DOCK6 MUSK

1.86e-041701436EFO_0008592
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

ACACB DNAH10 APOB MADD PCIF1 DOCK6 MUSK

1.91e-042431437EFO_0004612, EFO_0020944
Diseasecholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

ACACB DNAH10 APOB PCIF1 MUSK

2.03e-041101435EFO_0008317, EFO_0008596, EFO_0010351
Diseasechylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement

ACACB DNAH10 APOB PCIF1 MUSK

2.03e-041101435EFO_0004574, EFO_0008317, EFO_0008596
Diseasefree cholesterol to total lipids in medium HDL percentage

APOB MADD PCIF1 MUSK

2.09e-04601434EFO_0022282
Diseaseaortic valve stenosis (is_implicated_in)

APOB ELN

2.31e-0451432DOID:1712 (is_implicated_in)
Diseasetotal lipids in very large VLDL measurement

DNAH10 APOB PCIF1 MUSK

2.37e-04621434EFO_0022313
Diseasephospholipids in very large VLDL measurement

DNAH10 APOB PCIF1 MUSK

2.37e-04621434EFO_0022299
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

USP24 APOB MUSK

2.67e-04261433OBA_2045191
Diseasecholesterol in very large VLDL measurement

DNAH10 APOB PCIF1 MUSK

2.85e-04651434EFO_0022230
Diseasetotal lipids in large VLDL

DNAH10 APOB PCIF1 MUSK

3.20e-04671434EFO_0022175
Diseasefree cholesterol in large VLDL measurement

DNAH10 APOB PCIF1 MUSK

3.39e-04681434EFO_0022265
Diseaseaortic valve disease (implicated_via_orthology)

ADAMTS19 ELN

3.45e-0461432DOID:62 (implicated_via_orthology)
DiseaseSymptomatic Infantile Spasms

TSC2 CRH

3.45e-0461432C0393699
DiseaseCryptogenic Infantile Spasms

TSC2 CRH

3.45e-0461432C0393698
DiseaseHypsarrhythmia

TSC2 CRH

3.45e-0461432C0684276
DiseaseSalaam Seizures

TSC2 CRH

3.45e-0461432C1527366
DiseaseANEURYSM, INTRACRANIAL BERRY, 1 (disorder)

TGFBR3 ELN

3.45e-0461432C1862932
DiseaseNodding spasm

TSC2 CRH

3.45e-0461432C0546878
Diseasespasmus nutans

TSC2 CRH

3.45e-0461432C1527306
DiseaseJackknife Seizures

TSC2 CRH

3.45e-0461432C0553558
Diseasechildhood trauma measurement, alcohol consumption measurement

WSCD1 PCDHGC5 PTPRD HERC3

3.99e-04711434EFO_0007878, EFO_0007979
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ACACB DNAH10 APOB MADD PCIF1 DOCK6 MUSK

4.11e-042761437EFO_0004612, EFO_0020943
Diseasesphingomyelin measurement

WSCD1 APOB MADD PELP1 PCIF1 DOCK6 MUSK

4.30e-042781437EFO_0010118
Diseasephospholipids in large HDL measurement

APOB PCIF1 DOCK6 MUSK

4.44e-04731434EFO_0022190
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

ACACB DNAH10 APOB PCIF1 PLAUR MUSK

4.45e-042001436EFO_0004611, EFO_0020945
Diseasetotal lipids in large HDL

APOB MADD PCIF1 DOCK6

4.68e-04741434EFO_0022189
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

ACACB DNAH10 APOB PCIF1 MAP4K2 MUSK

5.20e-042061436EFO_0004612, EFO_0020947
Diseasefree cholesterol in large HDL measurement

APOB MADD DOCK6 MUSK

5.99e-04791434EFO_0022157
Diseasecholesterol in large HDL measurement

APOB MADD PCIF1 DOCK6

6.29e-04801434EFO_0021900
Disease1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6) measurement

PEX6 MUSK

6.41e-0481432EFO_0800392
Diseasecommon bile duct neoplasm (is_marker_for)

APOB TYMP

6.41e-0481432DOID:4608 (is_marker_for)
DiseaseNEURAL TUBE DEFECTS, SUSCEPTIBILITY TO

FUZ SCRIB

6.41e-0481432C3891448
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

ACACB DNAH10 DDX56 APOB PCIF1 MUSK

6.51e-042151436EFO_0008317, EFO_0008591
Diseasecreatinine measurement, chronic kidney disease

SLC34A1 AP5B1 PDILT

6.51e-04351433EFO_0003884, EFO_0004518
Diseaseserum metabolite measurement

TNPO1 SORBS2 APOB SMOC1 ABCA7 CDK10 PACRGL ERAP2 PCIF1 DOCK6 FAM20A MAP4K2 MUSK

7.13e-0494514313EFO_0005653
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

ACACB DNAH10 DDX56 APOB PCIF1 MUSK

7.34e-042201436EFO_0004529, EFO_0008317
Diseasenon-high density lipoprotein cholesterol measurement

TNPO1 USP34 DNAH10 WDR81 PEX6 DDX56 APOB SLC34A1 PCIF1 ASCC3 MUSK

7.35e-0471314311EFO_0005689
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

ACACB DNAH10 APOB PCIF1 MAP4K2 MUSK

8.06e-042241436EFO_0004530, EFO_0008317
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

ACACB DNAH10 DDX56 APOB PCIF1 MUSK

8.06e-042241436EFO_0004574, EFO_0008317
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

ACACB DNAH10 DDX56 APOB PCIF1 MUSK

8.25e-042251436EFO_0008317, EFO_0010351
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

ACACB APOB PCIF1 MUSK

8.25e-04861434EFO_0008595, EFO_0020945
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

ACACB DNAH10 DDX56 APOB PCIF1 MUSK

9.03e-042291436EFO_0004639, EFO_0008317
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

DDX56 APOB PCIF1 DOCK6 MUSK

9.18e-041531435EFO_0004611, EFO_0020944
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

DNAH10 PEX6 APOB MADD PCIF1 DOCK6 MUSK

1.00e-033211437EFO_0004612, EFO_0004639
Diseasesleep duration, low density lipoprotein cholesterol measurement

USP24 DDX56 APOB MUSK

1.02e-03911434EFO_0004611, EFO_0005271
Diseasecardiovascular system disease (is_marker_for)

APOB PLAUR

1.02e-03101432DOID:1287 (is_marker_for)
Diseasecholesteryl esters to total lipids in small LDL percentage

APOB PCIF1 MUSK

1.11e-03421433EFO_0022255
Diseasecytochrome p450 3a4 measurement

APOB CFD

1.25e-03111432EFO_0020303
Diseaselevel of Sphingomyelin (d34:0) in blood serum

PELP1 MUSK

1.25e-03111432OBA_2045176
Diseasehematocrit

RIPK3 HLF AFF3 PEX6 EXOC3 ZC3HC1 APOB CDK10 LRRC47 ARHGEF40 SLC34A1 PDILT MUSK

1.31e-03101114313EFO_0004348
Diseaseapolipoprotein B measurement

ACACB DNAH10 USP24 WDR81 PEX6 DDX56 APOB PCIF1 DOCK6 MUSK

1.51e-0366314310EFO_0004615
Diseasecholesteryl ester measurement

DNAH10 APOB MADD PCIF1 DOCK6 MUSK

1.63e-032571436EFO_0010351
DiseaseHbA1c measurement

ACACB FN3KRP ITGAD ANKH MADD LRRC47 GAB3 RAB40B MAP4K2 MUSK

1.72e-0367514310EFO_0004541
Diseasevery low density lipoprotein cholesterol measurement

ACACB DNAH10 DDX56 APOB PCIF1 MUSK

1.73e-032601436EFO_0008317
Diseasehuman Chorionic Gonadotropin measurement

TRPM4 RUVBL2

1.76e-03131432EFO_0008156
Diseaselevel of Phosphatidylinositol (18:1_18:1) in blood serum

DOCK6 MUSK

1.76e-03131432OBA_2045159
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement

ACACB DNAH10 APOB MUSK

1.79e-031061434EFO_0008317, EFO_0008596
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

DNAH10 USP24 DDX56 APOB PCIF1 MUSK

1.86e-032641436EFO_0008317, EFO_0020944
Diseasebody mass index, fasting blood glucose measurement

MADD MAP4K2 MUSK

1.96e-03511433EFO_0004340, EFO_0004465
Diseasesulfate measurement

SLC13A1 SLC34A1

2.04e-03141432EFO_0007864
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

ACACB DNAH10 APOB MUSK

2.05e-031101434EFO_0008317, EFO_0008591, EFO_0008596
Diseasetriglyceride measurement, high density lipoprotein cholesterol measurement

ACACB APOB SERPINA11 PCIF1 DOCK6 MAP4K2

2.25e-032741436EFO_0004530, EFO_0004612
Diseasetriglycerides to total lipids in chylomicrons and extremely large VLDL percentage

APOB PCIF1

2.35e-03151432EFO_0022328
Diseaseantihyperlipidemic drug use measurement

DCPS DDX56 APOB MUSK

2.41e-031151434EFO_0803367
Diseasetriglycerides in medium VLDL measurement

DNAH10 APOB PCIF1

2.43e-03551433EFO_0022155
DiseaseHOMA-B

TGFBR3 MAP4K2 MUSK

2.43e-03551433EFO_0004469
Diseasecholesterol to total lipids in large HDL percentage

APOB MADD PCIF1

2.43e-03551433EFO_0022234
Diseasevitamin C measurement

SLC34A1 MUSK

2.68e-03161432EFO_0600003
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

DDX56 APOB PCIF1 PLAUR

2.81e-031201434EFO_0004611, EFO_0004639
Diseasesexual dimorphism measurement

RIPK3 DNAH10 TUBG2 TSC2 APOB FRYL SAMHD1 DCAF16 MADD ARHGEF40 AP5B1 PCIF1 KPNA2

2.88e-03110614313EFO_0021796
Diseaseapolipoprotein A 1 measurement

ACACB DNAH10 AFF3 PEX6 RFX6 APOB TUBG1 MADD PCIF1 DOCK6 MUSK

2.88e-0384814311EFO_0004614
Diseasesleep duration, high density lipoprotein cholesterol measurement

APOB PCIF1 DOCK6 MUSK

2.90e-031211434EFO_0004612, EFO_0005271
Diseasetriglycerides in VLDL measurement

APOB PCIF1 MUSK

2.97e-03591433EFO_0022326
DiseaseMoyamoya Disease

SAMHD1 ELN

3.02e-03171432C0026654
Diseasealpha-L-iduronidase measurement

IDUA SLC26A1

3.02e-03171432EFO_0020139
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

APOB PCIF1

3.02e-03171432EFO_0022232
Diseasetriglycerides to total lipids in large HDL percentage

APOB MADD PCIF1

3.12e-03601433EFO_0022330
Diseasepulse pressure measurement

USP34 TRPM7 PCDHA13 FRYL SLC22A7 MADD TGFBR3 PIEZO2 PTPRD ARVCF SMIM38 PITPNM3 ELN MAP4K2 MUSK

3.17e-03139214315EFO_0005763
Diseasetriglycerides in small VLDL measurement

DNAH10 APOB PCIF1

3.27e-03611433EFO_0022145
Diseasefree cholesterol in very large VLDL measurement

DNAH10 APOB MUSK

3.27e-03611433EFO_0022274
Diseasefree cholesterol in HDL measurement

APOB PCIF1 DOCK6

3.27e-03611433EFO_0022264
Diseasephospholipids in HDL measurement

APOB PCIF1 DOCK6

3.27e-03611433EFO_0022293
Diseaselevel of Phosphatidylinositol (18:0_18:1) in blood serum

DOCK6 MUSK

3.39e-03181432OBA_2045155
Diseasephospholipids in large VLDL measurement

DNAH10 APOB PCIF1

3.42e-03621433EFO_0022169
Diseasetriglycerides in medium LDL measurement

APOB PCIF1 MUSK

3.42e-03621433EFO_0022322
Diseasetotal lipids in HDL measurement

APOB PCIF1 DOCK6

3.58e-03631433EFO_0022307

Protein segments in the cluster

PeptideGeneStartEntry
CVDLLPRPHLQELIV

C2orf16

631

Q68DN1
DLTLLSRIPEHLPQE

AFF3

771

P51826
QPDLLLLRHVPLTRV

SLC4A9

871

Q96Q91
DPPLVQRLLILIHDD

ARHGEF40

616

Q8TER5
QRLLILIHDDLPTEL

ARHGEF40

621

Q8TER5
GLPLLVALLDHPRAE

ARVCF

401

O00192
RLAVEVLHAADLLPL

BAIAP3

1026

O94812
RHPDLSIPELLRIVQ

AFM

361

P43652
VARILLTPPEHLERT

FDXR

191

P22570
ALLARALVHLSLVPP

ADCK5

556

Q3MIX3
LPPVRLAELHADLKI

LRPAP1

71

P30533
ILDLDLHLPLLCFRP

DENND3

186

A2RUS2
RDLTPEHLPLLRNIL

DCPS

231

Q96C86
LDPSTPVHILREIGL

DCAF16

81

Q9NXF7
LVEELPHELVLVLPY

ABCA7

1091

Q8IZY2
LLSLLLLVPVHPQRL

CA9

26

Q16790
PPELELLSLEAVHRA

REC8

471

O95072
VHLVDKLPLPIALRS

RAB40B

206

Q12829
VHLVDKLPLPIALRS

RAB40AL

206

P0C0E4
HLLPLLENPVIIDIF

RFX6

301

Q8HWS3
NLRVIKLILLHETPP

ADAMTS19

371

Q8TE59
PELLSLVHLDAVPRP

KLHL30

216

Q0D2K2
HGLLIPLLLIELETV

LRRC9

376

Q6ZRR7
HVLPLEAGLTPDILI

MAP4K2

681

Q12851
TLRHPSLPLLELQEI

ACACB

1031

O00763
RRPDSLQHVLLPVLD

CFD

161

P00746
PELRAHVIDKFLLLP

RENBP

276

P51606
SRLPLLLTHEGVLLP

LONP2

11

Q86WA8
TLVDFPLHLPLELLG

MADD

291

Q8WXG6
PTPLRAHDILHLVEL

NUDT18

151

Q6ZVK8
PDLFRDLEIIPALLH

FN3KRP

201

Q9HA64
PPLDLRNLSIIREHA

GAB3

451

Q8WWW8
TLEPLLARSPFLVLH

HERC3

691

Q15034
RLLLRVLHVSENPVP

LRRC47

306

Q8N1G4
LQLLRHDLPLHPAVV

DDX56

471

Q9NY93
LHALTRPPALLLLAA

NAT14

36

Q8WUY8
HEALLTLVVPPALLL

ITGA3

671

P26006
LIHPPERSDLTLYLI

PCDHGC5

681

Q9Y5F6
IQLPLEHPELLSLGL

PEX6

721

Q13608
IELVDLKPLPTARRH

FRYL

1316

O94915
ALIHRDLKPPNLLLV

MAP3K7

151

O43318
AIHLPPDSKLLLRLE

AP5B1

831

Q2VPB7
VLRSLLENPLKLPLH

HLF

21

Q16534
LLLVVAPPRVAALVH

PRSS38

21

A1L453
EPPISLDLTFHLLRE

CRH

156

P06850
DGPLRLLLLPSIHLE

PELP1

361

Q8IZL8
LLLCLLPLVRATEPH

GPR83

6

Q9NYM4
PLDEVDAPHHRLLVL

PCDHA13

636

Q9Y5I0
QILPTLVRLLHHDDP

KPNA2

251

P52292
PIILHLNFSLVREPI

ITGAD

726

Q13349
EVLERHEPLPAKLAL

SLC34A1

66

Q06495
PLLRPERKADLIIHL

PLA2G4E

711

Q3MJ16
LVLPPTREVHLILSF

PLA2G4C

396

Q9UP65
SLELPVLHVPRNLKL

APOB

3301

P04114
PLLHELLTHVRLPLL

KLHL24

246

Q6TFL4
DLEPRKVHLPELLRS

KLHL25

221

Q9H0H3
FLHQDLPLLVLPRQI

CARD6

486

Q9BX69
PPHPEVELLRSQLIL

PCIF1

196

Q9H4Z3
LPLLSIARDTLPRLH

DOCK6

1166

Q96HP0
ELLAHRPLLPGTSEI

CDK10

231

Q15131
HPALRSLRLLTLEQP

COMTD1

66

Q86VU5
HSHLECREPLLIPIL

ANKH

181

Q9HCJ1
IQDLIPVLLRHRLCP

COQ8B

466

Q96D53
LLPFVRIEHILPINS

BTBD7

516

Q9P203
REAPVPSLHLKLLSV

C20orf27

81

Q9GZN8
LRPALRLPSLLLVHV

IDUA

526

P35475
DLLPSRDRQHLPLIK

FGA

211

P02671
EVLALPELPSAHPII

DENND4B

1286

O75064
ELRLPSVVIPLHYDL

ERAP2

66

Q6P179
KLFTIERLHLPPDLS

ELP4

376

Q96EB1
SSTHVPLVLPLLVLL

CHADL

6

Q6NUI6
TLEPLLSPHVVSELL

EXOC3

366

O60645
LSQLPPELLLVVLSH

FBXO27

26

Q8NI29
PDLDRIIPVLLEHGL

LIG1

511

P18858
IIPVLLEHGLERLPE

LIG1

516

P18858
DLPILKIIPIEAHRL

DNAH10

4406

Q8IVF4
PGVLLLLLSILHPSR

ELN

11

P15502
VALLALPRVLLPLHF

SLC22A7

21

Q9Y694
VLQLHRVLPPDLKSL

SDHAF3

16

Q9NRP4
LVLLPLPIVLHTKEA

SLC13A1

21

Q9BZW2
LHQARLLALLVIPPA

CHID1

216

Q9BWS9
VPHRLLTLTLLPSLE

FUZ

231

Q9BT04
PLDREETPNHKLLVL

PCDH11Y

346

Q9BZA8
LPRLIPVLKAALVHS

PACRGL

156

Q8N7B6
PIPILELADHIERLK

PTPRD

1336

P23468
PIIIHRLLPHAVSSL

ORC3

256

Q9UBD5
ADHVRLLVPLVLEPG

MIEF2

191

Q96C03
PVHILEERSLLVLTP

PDILT

36

Q8N807
QSPHGIPIDLLDRLL

RUVBL2

341

Q9Y230
LLDIDPLILIHLLDL

TRIM37

611

O94972
PLLSLVLAHCDLPEL

RIN1

541

Q13671
THILNRVLPPDIRIL

PUS3

161

Q9BZE2
PVTPLHLDLTQLHRL

PLEKHN1

421

Q494U1
LDVLLLHRLVLLEVP

TDRD6

171

O60522
IELHPLLVRIIDTPQ

SAMHD1

126

Q9Y3Z3
ALPLLRVLSIRVDHP

LRRC41

546

Q15345
RLLLDIPLQTPHKLV

RGPD2

1161

P0DJD1
LPHRLLTDIISDGVP

KBTBD4

186

Q9NVX7
LSPVLTEPHLLALDR

FAM20A

486

Q96MK3
PLLPLDELHVLAEQL

NBEAL2

56

Q6ZNJ1
ADHLPPILLLRLIHL

NBEAL2

191

Q6ZNJ1
VLLSQLHLPTVLPDR

PIGQ

136

Q9BRB3
PDPLLALLVVILLAR

SMIM38

11

A0A286YFK9
PEEALPFLERLLLLH

SH3TC1

681

Q8TE82
RLAVLPPELAHTTEL

SCRIB

346

Q14160
ILHRLISELLPDVPE

SORBS2

756

O94875
LQEELHRLTLPLPKS

CCDC136

581

Q96JN2
ILPERHPPHTELLDL

ASCC3

1291

Q8N3C0
PLLRDPALDLKVIHL

CHST2

316

Q9Y4C5
PALDLKVIHLVRDPR

CHST2

321

Q9Y4C5
PLLSDPALNLRIVHL

CHST6

186

Q9GZX3
PDLILVHPVLALSGR

SHANK2-AS3

16

Q9BTD1
HLDLQLPSLRPEDLK

ZC3HC1

191

Q86WB0
LLKEFLHLDLTAPIP

PLEKHG5

561

O94827
TPHLLLVLVQLSPAR

SMOC1

11

Q9H4F8
LLVLEQFLSVLPPHL

ZSCAN10

31

Q96SZ4
LLPLLLLLHTCVPAS

PLAUR

6

Q03405
RLQVLHLLILILPEP

ARHGAP40

381

Q5TG30
HLLILILPEPNRNAL

ARHGAP40

386

Q5TG30
RTLPATVPLLLQHIL

TEP1

1386

Q99973
DDRVKLTEHLIPLLP

STAG3

571

Q9UJ98
PVLLHRDLKPSNVLL

RIPK3

136

Q9Y572
IPRAVLLDLEPRVIH

TUBG1

61

P23258
HRLRVPLPTELLVIV

SLC26A1

286

Q9H2B4
PRVLLQTLRHPIFLL

SLCO2B1

361

O94956
QLLLPSLLDLHLPRF

SERPINA11

301

Q86U17
HELILDFIRSRPPLK

SPIRE2

311

Q8WWL2
VFREELLPHLLPLLK

TNPO2

386

O14787
LLKPLVHLQLPRSDL

TBC1D23

131

Q9NUY8
LPPLTHELTASELLL

PIEZO2

1871

Q9H5I5
PSRPVLHLLQLLLRT

VWCE

791

Q96DN2
HEILSRDPLLLAIIP

XPO5

381

Q9HAV4
PHLLSPLLQLLRALV

NUP188

441

Q5SRE5
HRILEPGLNILIPVL

STOML2

56

Q9UJZ1
HQEARFLIPLLVPLV

PIGZ

386

Q86VD9
LHRGELQRVPTLLLP

RPAP1

1076

Q9BWH6
ELLPHILPLLKELLF

TNPO1

401

Q92973
ASRLEPLLEPKFHLV

PITPNM3

441

Q9BZ71
IRQLVRIDHIPDLPL

SOCS7

526

O14512
SPLLPLHEEVEALLF

USP24

2376

Q9UPU5
PPSLVQLILLSRIIH

SCN7A

1341

Q01118
IPRAVLLDLEPRVIH

TUBG2

61

Q9NRH3
SLIKNLDPVPLRHLL

USP34

431

Q70CQ2
ALHDPRVSPELLLGV

WSCD1

71

Q658N2
LLSLPDHPIAQLLRR

VPS9D1

276

Q9Y2B5
RRPHDPKTVDLILEL

TCHH

46

Q07283
LVRALPLALVLHELG

TYMP

391

P19971
SPPELRQRLHGVELL

TRPM7

1361

Q96QT4
APPFIVISHLRLLLR

TRPM4

1076

Q8TD43
PRISHEVLLPVLSFL

WDR81

1366

Q562E7
EVHTIPPELRILLDP

TGFBR3

366

Q03167
PERPLEARHAVLALL

TSC2

91

P49815
VPLLEFLSTLARLPH

TSC2

841

P49815
VVPLPDHLCRDDILL

WDR64

216

B1ANS9
LTTLPSELLLDRLHP

MUSK

536

O15146