Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	CYC1 RHCG SLC43A2 SLC46A2 ROMO1 SLC2A9 SLC16A9 MRS2 SLC6A16 SLC38A4 TMEM165 SLCO1B3 GRIA3 SLC35E2B SLC22A24 SLC29A2 SLCO1B7 CLCN1 SLC16A3 SLC17A9 SV2B SLC35E2A SLCO2A1 ABCB8 SCN9A OTOP1 SLC39A6 TIMM17A SV2C SLC30A9 SLC22A20P SLC4A11	2.46e-15	1180	103	32	GO:0022857
GeneOntologyMolecularFunction	transporter activity	CYC1 RHCG SLC43A2 SLC46A2 ROMO1 SLC2A9 SLC16A9 MRS2 SLC6A16 SLC38A4 TMEM165 SLCO1B3 GRIA3 SLC35E2B SLC22A24 SLC29A2 SLCO1B7 CLCN1 SLC16A3 SLC17A9 SV2B SLC35E2A SLCO2A1 ABCB8 SCN9A OTOP1 SLC39A6 TIMM17A SV2C SLC30A9 SLC22A20P SLC4A11	2.89e-14	1289	103	32	GO:0005215
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC46A2 SLC2A9 SLC16A9 SLC6A16 SLC38A4 TMEM165 SLCO1B3 SLC35E2B SLCO1B7 SLC16A3 SLC17A9 SLC35E2A SLCO2A1 SLC39A6 SLC30A9 SLC4A11	2.56e-12	296	103	16	GO:0015291
GeneOntologyMolecularFunction	active transmembrane transporter activity	CYC1 SLC46A2 SLC2A9 SLC16A9 SLC6A16 SLC38A4 TMEM165 SLCO1B3 SLC35E2B SLCO1B7 SLC16A3 SLC17A9 SLC35E2A SLCO2A1 ABCB8 SLC39A6 SLC30A9 SLC4A11	3.95e-11	477	103	18	GO:0022804
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC43A2 SLC46A2 SLC16A9 SLC38A4 SLCO1B3 GRIA3 SLCO1B7 SLC16A3 SLC17A9 SLCO2A1 SLC39A6 SLC22A20P SLC4A11	3.69e-09	293	103	13	GO:0008514
GeneOntologyMolecularFunction	symporter activity	SLC46A2 SLC2A9 SLC16A9 SLC6A16 SLC38A4 SLC16A3 SLC39A6 SLC4A11	1.09e-06	150	103	8	GO:0015293
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CYC1 RHCG SLC2A9 MRS2 SLC38A4 TMEM165 GRIA3 SLC16A3 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11	2.04e-05	627	103	13	GO:0022890
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CYC1 RHCG SLC2A9 MRS2 SLC38A4 TMEM165 GRIA3 CLCN1 SLC16A3 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11	3.44e-05	758	103	14	GO:0015318
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CYC1 ROMO1 SLC2A9 MRS2 SLC38A4 TMEM165 GRIA3 SLC16A3 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11	3.70e-05	664	103	13	GO:0008324
GeneOntologyMolecularFunction	prostaglandin transmembrane transporter activity	SLCO1B3 SLCO1B7 SLCO2A1	4.66e-05	14	103	3	GO:0015132
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CYC1 ROMO1 SLC2A9 MRS2 SLC38A4 TMEM165 GRIA3 CLCN1 SLC16A3 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11	5.62e-05	793	103	14	GO:0015075
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	SLCO1B3 SLCO1B7 SLCO2A1	5.80e-05	15	103	3	GO:0071714
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC43A2 SLC16A9 SLC38A4 SLCO1B3 GRIA3 SLCO1B7 SLC16A3	9.93e-05	207	103	7	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC43A2 SLC16A9 SLC38A4 SLCO1B3 GRIA3 SLCO1B7 SLC16A3	1.02e-04	208	103	7	GO:0005342
GeneOntologyMolecularFunction	sodium-independent organic anion transmembrane transporter activity	SLCO1B3 SLCO1B7 SLCO2A1	1.03e-04	18	103	3	GO:0015347
GeneOntologyMolecularFunction	guanine nucleotide transmembrane transporter activity	SLC46A2 SLC17A9	2.61e-04	5	103	2	GO:0001409
GeneOntologyMolecularFunction	antiporter activity	TMEM165 SLC35E2B SLC35E2A SLC30A9 SLC4A11	7.46e-04	138	103	5	GO:0015297
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	SLC16A9 SLCO1B3 SLCO1B7 SLC16A3	1.21e-03	90	103	4	GO:0008028
GeneOntologyMolecularFunction	MHC class II receptor activity	HLA-DOA HLA-DQB1	1.41e-03	11	103	2	GO:0032395
GeneOntologyMolecularFunction	transition metal ion transmembrane transporter activity	TMEM165 SLC39A6 SLC30A9	1.51e-03	44	103	3	GO:0046915
GeneOntologyBiologicalProcess	organic anion transport	SLC43A2 SLC46A2 SLC2A9 SLC16A9 SLC38A4 SLCO1B3 SLC22A24 SLCO1B7 SLC16A3 SLC17A9 SLCO2A1 SLC39A6 NMB SLC22A20P SLC4A11	2.69e-08	515	100	15	GO:0015711
GeneOntologyBiologicalProcess	monoatomic ion transport	CYC1 ROMO1 MYLK SLC2A9 ANK3 MRS2 SLC6A16 SLC38A4 TMEM165 SLCO1B3 GRIA3 SLC22A24 FASLG SLCO1B7 SLC35G1 CLCN1 ABCB8 SCN9A OTOP1 SLC39A6 SLC30A9 SLC22A20P SLC4A11 PLCE1	2.80e-08	1374	100	24	GO:0006811
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	CYC1 ROMO1 SLC2A9 ANK3 MRS2 SLC6A16 SLC38A4 TMEM165 GRIA3 FASLG SLC35G1 CLCN1 ABCB8 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11 PLCE1	1.47e-06	1115	100	19	GO:0034220
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	CYC1 RHCG SLC2A9 ANK3 MRS2 SLC6A16 SLC38A4 TMEM165 FASLG SLC35G1 CLCN1 ABCB8 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11 PLCE1	1.70e-06	1017	100	18	GO:0098660
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	CYC1 RHCG SLC2A9 ANK3 MRS2 SLC6A16 SLC38A4 TMEM165 FASLG SLC35G1 ABCB8 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11 PLCE1	1.98e-06	922	100	17	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	CYC1 ROMO1 SLC2A9 ANK3 MRS2 SLC6A16 SLC38A4 TMEM165 FASLG SLC35G1 ABCB8 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11 PLCE1	2.64e-06	942	100	17	GO:0098655
GeneOntologyBiologicalProcess	monoatomic cation transport	CYC1 ROMO1 MYLK SLC2A9 ANK3 MRS2 SLC6A16 SLC38A4 TMEM165 FASLG SLC35G1 ABCB8 SCN9A OTOP1 SLC39A6 SLC30A9 SLC4A11 PLCE1	1.02e-05	1157	100	18	GO:0006812
GeneOntologyBiologicalProcess	sodium-independent organic anion transport	SLCO1B3 SLCO1B7 SLCO2A1	4.82e-05	15	100	3	GO:0043252
GeneOntologyBiologicalProcess	cellular homeostasis	RHCG TMEM165 BOLA1 TXNRD2 FASLG LIN28A SLC35G1 OXCT1 TMTC4 SV2B ABCB8 SLC39A6 SLC30A9 SLC4A11 PLCE1	7.43e-05	981	100	15	GO:0019725
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	RHCG ANK3 TMEM165 BOLA1 FASLG SLC35G1 TMTC4 SV2B SLC39A6 SLC30A9 SLC4A11 PLCE1	1.55e-04	705	100	12	GO:0055080
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	RHCG ANK3 TMEM165 BOLA1 FASLG SLC35G1 TMTC4 SV2B SLC39A6 SLC30A9 SLC4A11 PLCE1	1.82e-04	717	100	12	GO:0050801
GeneOntologyBiologicalProcess	inorganic ion homeostasis	RHCG ANK3 TMEM165 BOLA1 FASLG SLC35G1 TMTC4 SV2B SLC39A6 SLC30A9 PLCE1	2.14e-04	622	100	11	GO:0098771
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	RHCG TMEM165 BOLA1 FASLG SLC35G1 TMTC4 SV2B SLC39A6 SLC30A9 SLC4A11 PLCE1	2.14e-04	622	100	11	GO:0006873
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	RHCG TMEM165 BOLA1 FASLG LIN28A SLC35G1 OXCT1 TMTC4 SV2B SLC39A6 SLC30A9 SLC4A11 PLCE1	2.80e-04	866	100	13	GO:0055082
GeneOntologyBiologicalProcess	chemical homeostasis	RHCG ANK3 TMEM165 BOLA1 FASLG LIN28A SLC35G1 OXCT1 TMTC4 SV2B PRKACG CD24 SLC39A6 SLC30A9 SLC4A11 PLCE1	3.22e-04	1249	100	16	GO:0048878
GeneOntologyBiologicalProcess	metal ion transport	MYLK ANK3 MRS2 SLC6A16 SLC38A4 TMEM165 FASLG SLC35G1 ABCB8 SCN9A SLC39A6 SLC30A9 SLC4A11 PLCE1	3.27e-04	1000	100	14	GO:0030001
GeneOntologyCellularComponent	basolateral plasma membrane	RHCG SLC43A2 SLC2A9 ANK3 SLCO1B3 SLC29A2 CLDN1 SLCO1B7 SLC16A3 SLCO2A1 SLC4A11	4.70e-07	320	102	11	GO:0016323
GeneOntologyCellularComponent	basal plasma membrane	RHCG SLC43A2 SLC2A9 ANK3 SLCO1B3 SLC29A2 CLDN1 SLCO1B7 SLC16A3 SLCO2A1 SLC4A11	1.27e-06	354	102	11	GO:0009925
GeneOntologyCellularComponent	basal part of cell	RHCG SLC43A2 SLC2A9 ANK3 SLCO1B3 SLC29A2 CLDN1 SLCO1B7 SLC16A3 SLCO2A1 SLC4A11	2.39e-06	378	102	11	GO:0045178
GeneOntologyCellularComponent	apical plasma membrane	RHCG SLC2A9 TMEM114 MPDZ SLC29A2 CLDN1 SLC16A3 SLC39A6 UPK2 SLC4A11	1.35e-04	487	102	10	GO:0016324
GeneOntologyCellularComponent	apical part of cell	RHCG SLC2A9 TMEM114 MPDZ SLC29A2 CLDN1 SLC16A3 SLC39A6 UPK2 SLC4A11	6.33e-04	592	102	10	GO:0045177
HumanPheno	Pruritus	CDSN HLA-DQB1 SLCO1B3 UNC45A CLDN1 JAK2 SLC17A9 SCN9A ALOX12B	9.72e-07	149	38	9	HP:0000989
MousePheno	decreased circulating serine level	SLC43A2 SLC38A4	2.84e-05	2	75	2	MP:0030695
MousePheno	decreased circulating histidine level	SLC43A2 SLC38A4	2.84e-05	2	75	2	MP:0011653
MousePheno	abnormal circulating serine level	SLC43A2 SLC38A4	8.49e-05	3	75	2	MP:0030693
MousePheno	decreased serine level	SLC43A2 SLC38A4	8.49e-05	3	75	2	MP:0030692
Domain	MFS_dom	SLC43A2 SLC46A2 SLC2A9 SLC16A9 SLCO1B3 SLC22A24 SLC29A2 SLCO1B7 SLC16A3 SLC17A9 SV2B SLCO2A1 SV2C SLC22A20P	1.67e-14	134	102	14	IPR020846
Domain	MFS	SLC43A2 SLC46A2 SLC2A9 SLC16A9 SLCO1B3 SLC22A24 SLCO1B7 SLC16A3 SLC17A9 SV2B SLCO2A1 SV2C SLC22A20P	2.35e-14	108	102	13	PS50850
Domain	MFS_1	SLC43A2 SLC46A2 SLC16A9 SLC22A24 SLC16A3 SLC17A9 SV2B SV2C	9.24e-09	77	102	8	PF07690
Domain	MFS	SLC43A2 SLC46A2 SLC16A9 SLC22A24 SLC16A3 SLC17A9 SV2B SV2C	9.24e-09	77	102	8	IPR011701
Domain	Sugar_transporter_CS	SLC2A9 SLC17A9 SV2B SV2C	2.68e-05	32	102	4	IPR005829
Domain	OA_transporter	SLCO1B3 SLCO1B7 SLCO2A1	3.36e-05	12	102	3	IPR004156
Domain	OATP	SLCO1B3 SLCO1B7 SLCO2A1	3.36e-05	12	102	3	PF03137
Domain	MFS_sugar_transport-like	SLC2A9 SV2B SV2C SLC22A20P	4.32e-05	36	102	4	IPR005828
Domain	Sugar_tr	SLC2A9 SV2B SV2C SLC22A20P	4.32e-05	36	102	4	PF00083
Domain	SV2	SV2B SV2C	8.83e-05	3	102	2	IPR022308
Domain	Pentapeptide_4	SV2B SV2C	8.83e-05	3	102	2	PF13599
Domain	5peptide_repeat	SV2B SV2C	1.76e-04	4	102	2	IPR001646
Domain	Kazal_2	SLCO1B3 SLCO1B7 SLCO2A1	9.91e-04	36	102	3	PF07648
Domain	Claudin_2	TMEM114 TMEM178B	1.04e-03	9	102	2	PF13903
Domain	Heme_NO-bd	GUCY1B2 TRAPPC6A	1.04e-03	9	102	2	IPR011644
Domain	Sugar_P_trans_dom	SLC35E2B SLC35E2A	1.29e-03	10	102	2	IPR004853
Domain	TPT	SLC35E2B SLC35E2A	1.29e-03	10	102	2	PF03151
Domain	Elongated_TPR_rpt_dom	UNC45A DNAJC7	1.57e-03	11	102	2	IPR023114
Domain	PMP22/EMP/MP20/Claudin	TMEM114 CLDN1 TMEM178B	1.90e-03	45	102	3	IPR004031
Domain	KAZAL_2	SLCO1B3 SLCO1B7 SLCO2A1	2.57e-03	50	102	3	PS51465
Domain	MHC_II_a/b_N	HLA-DOA HLA-DQB1	2.57e-03	14	102	2	IPR014745
Domain	EamA_dom	SLC35E2B SLC35G1	2.57e-03	14	102	2	IPR000620
Domain	EamA	SLC35E2B SLC35G1	2.57e-03	14	102	2	PF00892
Domain	-	HLA-DOA HLA-DQB1	2.57e-03	14	102	2	3.10.320.10
Domain	Kazal_dom	SLCO1B3 SLCO1B7 SLCO2A1	2.72e-03	51	102	3	IPR002350
Domain	TPR_8	UNC45A DNAJC7 TMTC4	3.04e-03	53	102	3	PF13181
Domain	SUGAR_TRANSPORT_2	SLC2A9 SLC17A9	3.81e-03	17	102	2	PS00217
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	RHCG SLC43A2 SLC2A9 SLC38A4 SLCO1B3 SLC29A2 SLCO1B7 SLC16A3 SLCO2A1 SLC39A6	8.09e-07	238	79	10	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	RHCG SLC43A2 SLC2A9 SLC38A4 SLCO1B3 SLC29A2 SLC16A3 SLCO2A1 SLC39A6	1.02e-05	249	79	9	M5988
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO1B3 SLCO1B7 SLCO2A1	3.59e-05	12	79	3	MM15476
Pathway	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	SLCO1B3 SLC29A2 SLCO1B7 SLCO2A1	7.90e-05	41	79	4	MM15075
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	RHCG SLC43A2 SLC2A9 MRS2 SLC38A4 SLCO1B3 SLC29A2 SLCO1B7 CLCN1 SLC16A3 SLCO2A1 ABCB8 SLC39A6	9.63e-05	681	79	13	MM14985
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	RHCG SLC43A2 SLC2A9 MRS2 SLC38A4 SLCO1B3 SLC29A2 CLCN1 SLC16A3 SLCO2A1 ABCB8 PRKACG SLC39A6	2.08e-04	736	79	13	M27287
Pathway	REACTOME_TOXICITY_OF_BOTULINUM_TOXIN_TYPE_D_BOTD	SV2B SV2C	3.07e-04	5	79	2	M27427
Pubmed	Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.	MRS2 ACADVL TMEM165 TMEM43 AK3 OXCT1 HERC2 SLC30A9 NEURL4	6.48e-06	438	103	9	32628020
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	CYC1 ROMO1 MRS2 ACADVL TMEM14C BOLA1 TXNRD2 COQ2 AK3 ALKBH1 OXCT1 ABCB8 TIMM17A SLC30A9	6.69e-06	1136	103	14	34800366
Pubmed	SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma.	SLC35E2B SLC35E2A	8.69e-06	2	103	2	35247439
Pubmed	Genetic variants of DNAH11 and LRFN2 genes and their association with ovarian and breast cancer.	LRFN2 DNAH11	8.69e-06	2	103	2	31605628
Pubmed	Autoreactive B-cell elimination by pathogenic IgG specific for the same antigen: implications for peripheral tolerance.	DSG3 FASLG	8.69e-06	2	103	2	18765425
Pubmed	CD24+ Ovarian Cancer Cells Are Enriched for Cancer-Initiating Cells and Dependent on JAK2 Signaling for Growth and Metastasis.	JAK2 CD24	8.69e-06	2	103	2	25969154
Pubmed	Observation of nine previously reported and 10 non-reported SLC4A11 mutations among 20 Iranian CHED probands and identification of an MPDZ mutation as possible cause of CHED and FECD in one family.	MPDZ SLC4A11	8.69e-06	2	103	2	31420327
Pubmed	Intronic polymorphisms in genes LRFN2 (rs2494938) and DNAH11 (rs2285947) are prognostic indicators of esophageal squamous cell carcinoma.	LRFN2 DNAH11	8.69e-06	2	103	2	31053115
Pubmed	Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location.	OR4F4 OR4F17	8.69e-06	2	103	2	11689484
Pubmed	Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes.	OR4F4 OR4F17	8.69e-06	2	103	2	11689483
Pubmed	Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb.	SV2B SLIT1 SV2C	1.37e-05	16	103	3	17715346
Pubmed	The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization.	SV2B SV2C VCL	1.99e-05	18	103	3	33514739
Pubmed	Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.	FASLG MAPK10	2.60e-05	3	103	2	11567045
Pubmed	Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis.	SV2B SV2C	2.60e-05	3	103	2	23617838
Pubmed	Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes.	PLEKHB2 PLEKHB1	2.60e-05	3	103	2	10200314
Pubmed	Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	18296417
Pubmed	Identification, sequence, and mapping of the mouse multiple PDZ domain protein gene, Mpdz.	ZDHHC21 MPDZ	2.60e-05	3	103	2	10395806
Pubmed	Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	30955241
Pubmed	Influence of drug formulation on OATP1B-mediated transport of paclitaxel.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	24755470
Pubmed	OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	29337310
Pubmed	Apoptosis Markers in Breast Cancer Therapy.	CYC1 FASLG	2.60e-05	3	103	2	27117663
Pubmed	Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	31967785
Pubmed	No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.	SV2B SV2C	2.60e-05	3	103	2	18977120
Pubmed	Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese.	LRFN2 DNAH11	2.60e-05	3	103	2	23103227
Pubmed	Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	18492796
Pubmed	Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	28389619
Pubmed	Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	23986199
Pubmed	SV2 is the protein receptor for botulinum neurotoxin A.	SV2B SV2C	2.60e-05	3	103	2	16543415
Pubmed	Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	18413659
Pubmed	Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina.	SV2B SV2C	2.60e-05	3	103	2	12687700
Pubmed	Expression of SV2 isoforms during rodent brain development.	SV2B SV2C	2.60e-05	3	103	2	23937191
Pubmed	SV2 modulates the size of the readily releasable pool of secretory vesicles.	SV2B SV2C	2.60e-05	3	103	2	11483953
Pubmed	Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	20949553
Pubmed	NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization.	HERC2 NEURL4	2.60e-05	3	103	2	28977907
Pubmed	Cellular expression of the monocarboxylate transporter (MCT) family in the placenta of mice.	SLC16A9 SLC16A3	2.60e-05	3	103	2	20022372
Pubmed	Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns.	SV2B SV2C	2.60e-05	3	103	2	33588752
Pubmed	Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	19400585
Pubmed	Synergistic interaction between genetics and disease on pravastatin disposition.	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	24613363
Pubmed	Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1).	SLCO1B3 SLCO1B7	2.60e-05	3	103	2	10833452
Pubmed	The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer.	SLC16A9 SLC16A3	2.60e-05	3	103	2	34097251
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	MPDZ SRP68 SEPHS1 ANAPC1 HERC2 NEURL4	4.18e-05	212	103	6	33853758
Pubmed	Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.	SLCO1B3 SLCO1B7	5.19e-05	4	103	2	22294745
Pubmed	Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.	SLCO1B3 SLCO1B7	5.19e-05	4	103	2	20644253
Pubmed	Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2.	HERC2 NEURL4	5.19e-05	4	103	2	31665549
Pubmed	The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.	JAK2 CD24	5.19e-05	4	103	2	21633165
Pubmed	Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.	SLCO1B3 SLCO1B7	5.19e-05	4	103	2	25280775
Pubmed	Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes.	OR4F4 OR4F17	5.19e-05	4	103	2	9384599
Pubmed	Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule.	MPDZ CLDN1	5.19e-05	4	103	2	11689568
Pubmed	Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.	SLCO1B3 SLCO1B7	5.19e-05	4	103	2	27777271
Pubmed	Lineage-specific gene duplication and loss in human and great ape evolution.	RALGAPA1 SLC2A9 SRP68 ANAPC1	5.41e-05	69	103	4	15252450
Pubmed	Epidermal development requires ninein for spindle orientation and cortical microtubule organization.	CDSN DSG3 CLDN1	6.24e-05	26	103	3	30923192
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	CYC1 ROMO1 MRS2 ACADVL TMEM14C BOLA1 TXNRD2 COQ2 AK3 OXCT1 ABCB8 TIMM17A	6.43e-05	1047	103	12	18614015
Pubmed	OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.	SLCO1B3 SLCO1B7	8.64e-05	5	103	2	24194565
Pubmed	PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis.	SLC38A4 ABCB8	8.64e-05	5	103	2	25063848
Pubmed	Variants of chemokine receptor 2 and interleukin 4 receptor, but not interleukin 10 or Fas ligand, increase risk of cervical cancer.	HLA-DQB1 FASLG	8.64e-05	5	103	2	17688234
Pubmed	HIV/SIV escape from immune surveillance: focus on Nef.	HLA-DOA HLA-DQB1 FASLG	8.72e-05	29	103	3	15078178
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	CYC1 ROMO1 MRS2 TMEM14C BOLA1 TXNRD2 COQ2 AK3 OXCT1 ABCB8 TIMM17A	9.65e-05	926	103	11	20877624
Pubmed	In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.	SLC35E2B OXCT1 SLC16A3 SLC35E2A CD24	1.18e-04	160	103	5	23375831
Pubmed	Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3.	RHCG SV2B	1.29e-04	6	103	2	18367154
Pubmed	Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.	SLCO1B3 SLCO1B7	1.29e-04	6	103	2	22232210
Pubmed	Analysis of DNA methylation and histone modification profiles of liver-specific transporters.	SLCO1B3 SLCO1B7	1.29e-04	6	103	2	19047482
Pubmed	A comparative transcript map and candidates for mutant phenotypes in the Tyrp1 (brown) deletion complex homologous to human 9p21-23.	ZDHHC21 MPDZ	1.29e-04	6	103	2	10602994
Pubmed	SV2B regulates synaptotagmin 1 by direct interaction.	SV2B SV2C	1.29e-04	6	103	2	15466855
Pubmed	Pulmonary neuroendocrine cells, airway innervation, and smooth muscle are altered in Cftr null mice.	SV2B SV2C	1.29e-04	6	103	2	16614351
Pubmed	β-Catenin gain of function in muscles impairs neuromuscular junction formation.	SV2B SLIT1 SV2C	1.41e-04	34	103	3	22627288
Pubmed	The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.	CYC1 ACADVL TXNRD2 AK3 OXCT1 ABCB8 SLC30A9	1.46e-04	382	103	7	29222160
Pubmed	Tmem2 Deficiency Leads to Enamel Hypoplasia and Soft Enamel in Mouse.	CLDN1 VCL	1.81e-04	7	103	2	37449307
Pubmed	Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.	CYC1 ROMO1 ACADVL BOLA1 COQ2 OXCT1 SLC30A9	2.36e-04	413	103	7	27499296
Pubmed	Genotype-phenotype correlations in non-Finnish congenital nephrotic syndrome.	COQ2 PLCE1	2.40e-04	8	103	2	20507940
Pubmed	Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.	ANK3 VCL	2.40e-04	8	103	2	28826662
Pubmed	Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice.	SLC38A4 SLC16A3	2.40e-04	8	103	2	31570606
Pubmed	Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family.	SLC22A24 SLC22A20P	2.40e-04	8	103	2	17714910
Pubmed	Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.	SLC2A9 OTOP1	2.40e-04	8	103	2	12651873
Pubmed	Synaptobrevin is essential for secretion but not for the development of synaptic processes.	SV2B SV2C	2.40e-04	8	103	2	8738414
Pubmed	ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.	ROMO1 TIMM17A	2.40e-04	8	103	2	30598479
Pubmed	Predictive value of 8 genetic loci for serum uric acid concentration.	SLC2A9 SLC16A9	2.40e-04	8	103	2	20162742
Pubmed	Common variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time series.	SLC2A9 SLC16A9	2.40e-04	8	103	2	20162743
Pubmed	Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.	JAK2 HERC2	3.08e-04	9	103	2	26692333
Pubmed	Functional proteomics mapping of a human signaling pathway.	PLEKHB2 ANK3 UNC45A TEX10 DNAJC7 PRDM4 HERC2 VCL	3.83e-04	591	103	8	15231748
Pubmed	Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.	SLCO1B3 SLCO1B7	3.85e-04	10	103	2	18703564
Pubmed	Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation.	CDSN CLDN1	3.85e-04	10	103	2	16192310
Pubmed	Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation.	SV2B SV2C	3.85e-04	10	103	2	10398046
Pubmed	The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.	HERC2 NEURL4	3.85e-04	10	103	2	26355680
Pubmed	Generation of GABAergic and dopaminergic interneurons from endogenous embryonic olfactory bulb precursor cells.	SV2B SV2C	3.85e-04	10	103	2	17038521
Pubmed	Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects.	ICOSLG HERC2	3.85e-04	10	103	2	20176734
Pubmed	RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain.	HERC2 NEURL4	3.85e-04	10	103	2	29097665
Pubmed	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	SLC2A9 SLC16A9	3.85e-04	10	103	2	19503597
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 ANK3 MRS2 ACADVL MPDZ UNC45A DNAJC7 NCKAP5L SLC39A6 HERC2 SLC30A9 NEURL4 VCL	4.53e-04	1487	103	13	33957083
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	ANK3 ACADVL TXNRD2 OXCT1 ABCB8 VCL	4.68e-04	331	103	6	29199018
Pubmed	Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease.	SLC2A9 SLC16A9	4.69e-04	11	103	2	19890391
Pubmed	Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.	SV2B SV2C	4.69e-04	11	103	2	12403715
Pubmed	Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.	SLCO1B3 SLCO2A1	4.69e-04	11	103	2	14579113
Pubmed	The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.	CDSN PLEKHB1 LIN28A AK3 DNAH11	5.12e-04	220	103	5	24705354
Pubmed	Multiple roles of integrin-α3 at the neuromuscular junction.	SV2B SV2C	5.62e-04	12	103	2	28386022
Pubmed	HIV-1 Nef impairs MHC class II antigen presentation and surface expression.	HLA-DOA HLA-DQB1	5.62e-04	12	103	2	11593029
Pubmed	Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.	HLA-DOA HLA-DQB1	5.62e-04	12	103	2	12970439
Pubmed	The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.	SLCO1B3 SLCO1B7	6.63e-04	13	103	2	11682476
Pubmed	Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression.	SV2B SV2C	6.63e-04	13	103	2	23637329
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	PRDM4 PLEKHM1 SCN9A NEURL4 DNAH11	6.64e-04	233	103	5	37704626
Pubmed	Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase.	SV2B SV2C	7.72e-04	14	103	2	12441053
GeneFamily	Solute carriers	RHCG SLC43A2 SLC46A2 SLC2A9 SLC16A9 SLC6A16 SLC38A4 SLCO1B3 SLC35E2B SLC22A24 SLC29A2 SLCO1B7 SLC35G1 SLC16A3 SLC17A9 SLC35E2A SLCO2A1 SLC39A6 SLC30A9 SLC22A20P SLC4A11	3.03e-18	395	73	21	752
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CLDN1 SLC16A3 SV2B SLCO2A1 SCN9A SV2C	2.45e-06	166	103	6	6a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 TSPAN2 LRFN2 TMEM178B SLC4A11 PLCE1	4.04e-06	181	103	6	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 TSPAN2 LRFN2 TMEM178B SLC4A11 PLCE1	4.04e-06	181	103	6	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	mild_COVID-19-B_intermediate\|World / disease group, cell group and cell class (v2)	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 CD24 PLCE1	6.56e-06	197	103	6	e909b898b7458071f176b6c04356ea3540589153
ToppCell	mild-B_intermediate\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 MAPK10 PLCE1	7.15e-06	200	103	6	8e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CDSN LIN28A OTOP1 UPK2	3.24e-05	78	103	4	564ea2c113058df595c3b69827cf9a72380b48fc
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CDSN LIN28A OTOP1 UPK2	3.24e-05	78	103	4	dfe16ac0b10dce7ecf4b3a0b4e1013ac58cb9fc1
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CDSN LIN28A OTOP1 UPK2	3.24e-05	78	103	4	6aa418ea30dfa7df2fc08cac5b31e3a654aaa7f0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 LRFN2 SLIT1 SLC4A11 PLCE1	3.33e-05	158	103	5	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 LRFN2 SLIT1 SLC4A11 PLCE1	3.33e-05	158	103	5	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICOSLG HLA-DOA TEX10 DNAJC7 CD24	3.43e-05	159	103	5	74655c22e9fdd88e3052b9dfb954c8fb678bd2d8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC43A2 ABHD3 CLDN1 TLDC2 PLCE1	4.09e-05	165	103	5	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CLDN1 LRFN2 TMEM178B SLC4A11 PLCE1	4.46e-05	168	103	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ICOSLG HLA-DOA CLDN1 JAK2 PLCE1	4.58e-05	169	103	5	b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TEX10 FASLG SLC17A9 SV2C NEURL4	4.71e-05	170	103	5	bda900c836e0f2c1d7b442beb50b672d025b2420
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	MYLK CLDN1 TMEM178B SLC4A11 PLCE1	4.98e-05	172	103	5	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOA CLDN1 JAK2 CD24 PLCE1	4.98e-05	172	103	5	a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCell	severe-B_memory\|severe / disease stage, cell group and cell class	ZDHHC21 HLA-DOA HLA-DQB1 ALKBH1 CD24	5.12e-05	173	103	5	3a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DOA HLA-DQB1 TMEM178B SLC4A11 DNAH11	5.26e-05	174	103	5	16204ff504b7b382b4d90ca35003ad5336020e07
ToppCell	droplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOA CLDN1 JAK2 SV2B CD24	5.26e-05	174	103	5	2afa5eea54b67c549c5058ece98296eee3829c11
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDSN PLEKHB1 SLC16A3 UPK2 NMB	5.71e-05	177	103	5	ea2c2d2d7ffd34780882299229ff8614fdd7c79c
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDSN PLEKHB1 SLC16A3 UPK2 NMB	5.71e-05	177	103	5	63b5ebbe505f22091bc7b0db818e01fae5d92bb7
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	MYLK CLDN1 TSPAN2 SLC4A11 PLCE1	6.02e-05	179	103	5	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	SLC43A2 SLC46A2 TMTC4 SLC22A20P DNAH11	6.02e-05	179	103	5	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 GRIA3 PLEKHB1 SV2C PLCE1	6.18e-05	180	103	5	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 GRIA3 PLEKHB1 SV2C PLCE1	6.18e-05	180	103	5	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 GRIA3 PLEKHB1 SV2C PLCE1	6.18e-05	180	103	5	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 OXCT1 CD24 SLC4A11 DNAH11	7.04e-05	185	103	5	af86e75096c1812ae27a78405355957ee8043d84
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 TSPAN2 LRFN2 SLC4A11 PLCE1	7.04e-05	185	103	5	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 TSPAN2 LRFN2 SLC4A11 PLCE1	7.04e-05	185	103	5	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	(5)_Epithelial_cells-(5)_Glands_duct\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	SLCO1B3 PLEKHB1 SLIT1 PNMA6A SLC4A11	7.22e-05	186	103	5	219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 OXCT1 SLC16A3 TLDC2 DNAH11	7.22e-05	186	103	5	c2b65b8345487710704c3eb043e9bef2e2b1ff27
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	SLC43A2 CLDN1 OXCT1 TLDC2 DNAH11	7.40e-05	187	103	5	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 LRFN2 TMEM178B SLC4A11 PLCE1	7.59e-05	188	103	5	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZDHHC21 HLA-DOA HLA-DQB1 CD24 PLCE1	7.59e-05	188	103	5	18d16e3f095a109b6a690f46fe7fcd5674c3636b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLDN1 LRFN2 TMEM178B SLC4A11 PLCE1	7.59e-05	188	103	5	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ICOSLG HLA-DOA HLA-DQB1 PRDM4 CD24	7.78e-05	189	103	5	886dceacf96e2b6750c146a381da0bf96a2bb15b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ICOSLG HLA-DOA HLA-DQB1 PRDM4 CD24	7.78e-05	189	103	5	5f1f4321939877374a8ee13de93f2d1390af8e2e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ICOSLG HLA-DOA HLA-DQB1 PRDM4 CD24	7.98e-05	190	103	5	60bb6aaea9691d07295f61c14d1650f5041a0f9c
ToppCell	tumor_Lung-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	HLA-DQB1 TMEM14C CLDN1 SCN9A DMWD	7.98e-05	190	103	5	58a6ab70737d719ca9725ac087f20dfe9be0463e
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 CD24	8.18e-05	191	103	5	b7d17d3ba488378b30f3732f8109f4a7c1673e61
ToppCell	10x5'-bone_marrow-Lymphocytic_B-Memory_B_cells\|bone_marrow / Manually curated celltypes from each tissue	ZDHHC21 HLA-DOA HLA-DQB1 PRDM4 CD24	8.18e-05	191	103	5	67479df0ca4c5a792fd604aded3f75609fec0888
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	ANK3 MPDZ CLDN1 CD24 MAPK10	8.38e-05	192	103	5	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZDHHC21 HLA-DOA HLA-DQB1 CD24 MAPK10	8.38e-05	192	103	5	f9f64ad7bab1433e9a45adb7db7f43ce3f591b47
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZDHHC21 HLA-DOA HLA-DQB1 CD24 MAPK10	8.38e-05	192	103	5	4884fd8ffa6fd6c30d7ac6bf447456b3397eabc5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZDHHC21 ICOSLG HLA-DQB1 PRDM4 CD24	8.59e-05	193	103	5	bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCell	COVID-19_Severe-Lymphoid_B-B_intermediate\|COVID-19_Severe / Disease group, lineage and cell class	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 CD24	8.59e-05	193	103	5	ea079e6f7242a2bbc8260299ad9e9bdabb9856f8
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZDHHC21 HLA-DOA HLA-DQB1 CD24 MAPK10	8.59e-05	193	103	5	8f1d6024ef092923321e6efd441b8d476db70aed
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 CD24	8.59e-05	193	103	5	b5e44fe60dc84dc050d4fa3ccec4e257e51dc636
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 CD24	8.59e-05	193	103	5	e2cf2f4f142e1b4dda3ded28b5208eef3f301a43
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 CD24	8.80e-05	194	103	5	7f62bd52779e2779447b23bdd330be4b5b35910a
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHB2 ANK3 SLC35G1 CD24 UPK2	8.80e-05	194	103	5	1531dcace28a14bd700e909a027426a8cee20337
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZDHHC21 HLA-DOA HLA-DQB1 CD24 PLCE1	8.80e-05	194	103	5	2b61023a602d336ed0de174e9141046173db34e6
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2\|World / Primary Cells by Cluster	PLEKHB2 ANK3 SCN9A SV2C MAPK10	8.80e-05	194	103	5	b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2-10\|World / Primary Cells by Cluster	PLEKHB2 ANK3 SCN9A SV2C MAPK10	8.80e-05	194	103	5	81e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCell	COVID-19_Mild-Lymphoid_B-B_intermediate\|COVID-19_Mild / Disease group, lineage and cell class	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 CD24	8.80e-05	194	103	5	bf6f72a489c62cbf1a679552d8c5eaaaa0b99d33
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZDHHC21 HLA-DOA HLA-DQB1 CD24 PLCE1	8.80e-05	194	103	5	2b5eee7c3e52b63cce94205d18133c7704329c02
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZDHHC21 HLA-DOA HLA-DQB1 CD24 PLCE1	8.80e-05	194	103	5	f2486b19ac52a48d19f80b38a5536bee3dad745b
ToppCell	PBMC-Severe-Lymphocyte-B\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ICOSLG HLA-DOA HLA-DQB1 SLC17A9 CD24	8.80e-05	194	103	5	7dbedbdece4271e10134c9338c85cb3e04484c75
ToppCell	PBMC-Severe-Lymphocyte-B\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICOSLG HLA-DOA HLA-DQB1 SLC17A9 CD24	8.80e-05	194	103	5	bd2c53fb064edfec76abe56a9ffaced0bda32ab0
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CLDN1 TSPAN2 SLC4A11 PLCE1	8.80e-05	194	103	5	1374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	ANK3 MPDZ CD24 MAPK10 DNAH11	9.01e-05	195	103	5	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ANK3 MPDZ CD24 MAPK10 DNAH11	9.01e-05	195	103	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	ANK3 MPDZ CD24 MAPK10 DNAH11	9.01e-05	195	103	5	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	droplet-Kidney-nan-3m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYC1 SLC43A2 ANK3 AK3 OXCT1	9.23e-05	196	103	5	9f39cb3de886283da34ee7511a92d94930a6c851
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_monocytic\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RHCG DSG3 HLA-DQB1 CLDN1 CD24	9.23e-05	196	103	5	03de28e1c963e99623e8b0e33bf2e8ef67dc3baa
ToppCell	droplet-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYC1 SLC43A2 ANK3 AK3 OXCT1	9.23e-05	196	103	5	b880c9665d42c76ea1971d4e49d7ecf72fcfafb6
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HLA-DOA HLA-DQB1 TMEM14C JAK2 SCN9A	9.23e-05	196	103	5	0bac14c018487ca67e7f9255b5f186e7ae665774
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DOA HLA-DQB1 TMEM14C JAK2 SCN9A	9.23e-05	196	103	5	33345338c825484960daa1ed82a19df38ccfc5c0
ToppCell	severe_COVID-19-B_memory\|severe_COVID-19 / disease group, cell group and cell class (v2)	HLA-DOA HLA-DQB1 PRDM4 CD24 PLCE1	9.23e-05	196	103	5	c6e00cb59a88b9903cca233cefe05f80c5ea4153
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CLDN1 TSPAN2 SLC4A11 PLCE1	9.23e-05	196	103	5	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	(5)_Epi_stratified\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	RHCG ROMO1 DSG3 CLDN1 CD24	9.46e-05	197	103	5	2b35bcff0637cd5af9bec1ac6bca2b59a92e2f64
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RHCG DSG3 HLA-DQB1 CLDN1 CD24	9.46e-05	197	103	5	e621d4f9d4ba5e3ef17d2b477e5e14ea0251147e
ToppCell	(5)_Epithelial_cells-(5)_Epi_stratified\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	RHCG ROMO1 DSG3 CLDN1 CD24	9.69e-05	198	103	5	b3aec042912ce53bd86e86b6761a0604d9998ab5
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_intermediate\|COVID-19_Mild / Disease, condition lineage and cell class	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 PLCE1	9.92e-05	199	103	5	1c6a08d01f6c1a2a4b6587d3a4522efbd03275e1
ToppCell	mild-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HLA-DOA HLA-DQB1 TMEM14C JAK2 SCN9A	1.02e-04	200	103	5	86f585bf9066b179bbcbc703bf43f15da4a07284
ToppCell	severe-B_intermediate\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 MAPK10	1.02e-04	200	103	5	6d0ac3d00400dd5657ee266f7b885381bf790ce1
ToppCell	mild-B_intermediate\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZDHHC21 ICOSLG HLA-DOA HLA-DQB1 MAPK10	1.02e-04	200	103	5	fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHCG SLC43A2 SLC29A2 PLCE1	1.91e-04	123	103	4	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RHCG SLC43A2 GPR78 SV2B	2.50e-04	132	103	4	7d6cd16ca1d83d9a618ef5b7fb300c1509eeb129
ToppCell	LPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets\|LPS_only / Treatment groups by lineage, cell group, cell type	BOLA1 TSPAN2 ABCB8 HERC2	2.96e-04	138	103	4	6ddd50e44a3914596b4cd61ae64a987119fe7979
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TLDC2 SCN9A PLCE1 DNAH11	3.67e-04	146	103	4	ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-cDC2-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HLA-DOA HLA-DQB1 CLDN1 SLC16A3	3.76e-04	147	103	4	c5913cc351577e54536dd239a33e5f7a5cb79672
ToppCell	COVID-19_Severe-B_cell\|World / disease group, cell group and cell class	ICOSLG DSG3 HLA-DQB1 LRFN2	3.96e-04	149	103	4	9a9fcbf7e8a6811958f3fd2d36315e19ab2b1127
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICOSLG HLA-DOA HLA-DQB1 CD24	4.06e-04	150	103	4	d9931507257c64ead4a53786e6822f51962c6015
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DQB1 SLC29A2 CD24 MAPK10	4.06e-04	150	103	4	4bdcdce40f54580c7a4e1416b468e657ba8874fc
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MPDZ CLDN1 SLC39A6 SV2C	4.27e-04	152	103	4	fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCell	COVID-19_Severe-B_cell\|COVID-19_Severe / disease group, cell group and cell class	ICOSLG DSG3 HLA-DQB1 LRFN2	4.38e-04	153	103	4	701a7d92ee7b22277c8462742a530347cc6f061a
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cbln1_(VTA_(dorsal_VTA))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DSG3 SLC38A4 TNN	4.39e-04	64	103	3	1b75c6ea17ba7efa83ffe8ae07a863abcdad542c
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cbln1_(VTA_(dorsal_VTA))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DSG3 SLC38A4 TNN	4.39e-04	64	103	3	275b4c418dc631a0925d6516cee6bf217cb7240a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TMEM114 SV2C UPK2 ALOX12B	4.49e-04	154	103	4	e23cc5688ff6299d2609f7fce73ee458139a99e0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM114 TSPAN2 SLC4A11 PLCE1	4.60e-04	155	103	4	90e629681a72baacc7981b82883866a487638dbc
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HLA-DOA HLA-DQB1 TMEM14C SCN9A	4.60e-04	155	103	4	ab539c04f10276ae919d82b1c75f99a84eb695bf
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DOA HLA-DQB1 TMEM14C SCN9A	4.60e-04	155	103	4	9a27558c457f05808af07190b7a5006b047f1d58
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DQB1 TEX10 SEPHS1 NMB	4.60e-04	155	103	4	96c48d835725eac1bc7926f4cddecb67c29b7d7c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RHCG ANK3 LIN28A SLC39A6	4.71e-04	156	103	4	a4b0e89255ea5d60198cb2b3e739981f9c9cf5c5
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MPDZ CLDN1 CD24 SV2C	4.82e-04	157	103	4	516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCell	droplet-Lung-LUNG-1m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIN28A SLC16A3 CD24 SLC22A20P	4.94e-04	158	103	4	30cceb73cf5e24b692da84d33342fd3b1ad5efe5
ToppCell	droplet-Heart-nan-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIN28A SLC16A3 CD24 SLC22A20P	4.94e-04	158	103	4	81a5a73090804d41429d297ba2462a842f39d380
ToppCell	Fetal_29-31_weeks-Immune-mast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FASLG PLEKHB1 TSPAN2 UPK2	4.94e-04	158	103	4	0c27c475289c70b17b6a66fc71f628511c5f0ae1
Disease	lung carcinoma, squamous cell carcinoma, gastric carcinoma	LRFN2 DNAH11	1.03e-05	2	95	2	EFO_0000178, EFO_0000707, EFO_0001071
Disease	tetradecenoylcarnitine meaasurement	ACADVL ALOX12B	3.07e-05	3	95	2	EFO_0021809
Disease	bilirubin metabolic disorder (implicated_via_orthology)	SLCO1B3 SLCO1B7	1.02e-04	5	95	2	DOID:2741 (implicated_via_orthology)
Disease	Crohn's disease (is_implicated_in)	HLA-DQB1 CLDN1 JAK2	1.23e-04	30	95	3	DOID:8778 (is_implicated_in)
Disease	hyperuricemia (implicated_via_orthology)	SLC2A9 JAK2	2.13e-04	7	95	2	DOID:1920 (implicated_via_orthology)
Disease	bipolar II disorder	OXCT1 SLIT1	2.84e-04	8	95	2	EFO_0009964
Disease	hexadecenedioate (C16:1-DC) measurement	SLCO1B3 SLCO1B7	3.64e-04	9	95	2	EFO_0800562
Disease	metabolite measurement	SLC2A9 ANK3 SLC16A9 ACADVL TMEM14C SLC22A24 ABCB8 TMEM178B	4.58e-04	560	95	8	EFO_0004725
Disease	Cleft palate, tobacco smoke exposure measurement, cleft lip, parental genotype effect measurement	ANK3 MAPK10	5.54e-04	11	95	2	EFO_0003959, EFO_0005939, EFO_0009115, HP_0000175
Disease	glycochenodeoxycholate glucuronide (1) measurement	SLCO1B3 SLCO1B7	7.82e-04	13	95	2	EFO_0800474
Disease	eosinophil percentage of granulocytes	ICOSLG HLA-DQB1 JAK2 ANAPC1 TUBD1	9.75e-04	234	95	5	EFO_0007996
Disease	allergic sensitization measurement	HLA-DQB1 FASLG ANAPC1	1.07e-03	62	95	3	EFO_0005298
Disease	systemic lupus erythematosus	HLA-DOA SLC6A16 HLA-DQB1 GPR78 COQ2 FASLG PLEKHM1 JAK2 NEURL4	1.10e-03	799	95	9	MONDO_0007915
Disease	Ulcerative Colitis	ICOSLG JAK2 HERC2	1.12e-03	63	95	3	C0009324
Disease	sclerosing cholangitis	CDSN HLA-DOA HLA-DQB1	1.28e-03	66	95	3	EFO_0004268
Disease	squamous cell carcinoma	LRFN2 HERC2 DNAH11	1.33e-03	67	95	3	EFO_0000707
Disease	X-21441 measurement	SLCO1B3 SLCO1B7	1.35e-03	17	95	2	EFO_0800814
Disease	ulcerative colitis (is_implicated_in)	HLA-DQB1 JAK2	1.35e-03	17	95	2	DOID:8577 (is_implicated_in)
Disease	ankylosing spondylitis (is_implicated_in)	HLA-DQB1 JAK2	1.69e-03	19	95	2	DOID:7147 (is_implicated_in)
Disease	multiple sclerosis (is_implicated_in)	HLA-DQB1 FASLG CD24	1.71e-03	73	95	3	DOID:2377 (is_implicated_in)
Disease	chronic myeloid leukemia (is_implicated_in)	HLA-DQB1 FASLG	2.07e-03	21	95	2	DOID:8552 (is_implicated_in)
Disease	HbA1c measurement, response to sulfonylurea	SLC16A9 SLCO1B7	2.07e-03	21	95	2	EFO_0004541, EFO_0007922
Disease	breast cancer, COVID-19	PLEKHM1 THBS3	2.27e-03	22	95	2	MONDO_0007254, MONDO_0100096
Disease	Acute Lung Injury	MYLK FASLG	2.27e-03	22	95	2	C0242488
Disease	autoimmune disease	HLA-DOA HLA-DQB1 FASLG NEURL4	2.40e-03	173	95	4	EFO_0005140
Disease	frailty measurement	ANK3 HLA-DQB1	2.48e-03	23	95	2	EFO_0009885
Disease	chronic hepatitis B virus infection	HLA-DOA HLA-DQB1	2.70e-03	24	95	2	EFO_0004239
Disease	hepatocellular carcinoma (is_marker_for)	SLCO1B3 FASLG CLDN1 AK3 JAK2	2.93e-03	301	95	5	DOID:684 (is_marker_for)
Disease	pre-eclampsia (is_implicated_in)	HLA-DQB1 FASLG	2.93e-03	25	95	2	DOID:10591 (is_implicated_in)
Disease	gastric carcinoma	THBS3 LRFN2 PLCE1	3.01e-03	89	95	3	EFO_0000178

Protein segments in the cluster

Peptide	Gene	Start	Entry
VGSQLAVMMYLSLGG	B4GALT3	16	O60512
MGRAMVARLGLGLLL	CD24	1	P25063
HSGDIMIMSGFSRLL	ALKBH1	271	Q13686
FLGGRLAMMLGFTEE	DNAH11	61	Q96DT5
AAGVSMGGMLLLNYL	ABHD3	216	Q8WU67
GRKVMLSALGMLAAG	CYC1	56	P08574
MLSGRLVLGLVSMAG	BOLA1	1	Q9Y3E2
RVGGHGMMALLLAGL	CDSN	11	Q15517
MLLRGLMKSYFGGLL	DMWD	316	Q09019
MLPNMRIGALGFSGA	JAK2	821	O60674
RTMALPVGRGMFTLF	ANAPC1	1076	Q9H1A4
MMGLFPRTTGALAIF	DSG3	1	P32926
VTIFSGFMVAGGLML	SLC16A9	81	Q7RTY1
MLSLFGTGAILMRGA	COQ2	111	Q96H96
GRLSSMAMISGLSGR	MYLK	1756	Q15746
LDFGLARTAGTSFMM	MAPK10	206	P53779
LSMFMGAGDAPLGSR	NCKAP5L	406	Q9HCH0
MLVGGLFASLGMVAA	SLC16A3	91	O15427
GRRFMIDLLVGSLMA	HERC2	926	O95714
MFGDLRSTFIALMIG	SLC43A2	171	Q8N370
MGASARLLRAVIMGA	AK3	1	Q9UIJ7
GVFYILVGGLGLAMM	GRIA3	826	P42263
SRVMNIGLGVLMRGF	OR51B4	136	Q9Y5P0
GGSEMVILIAMGFDR	OR4F5	101	Q8NH21
LFGLMGVAFGMNLES	MRS2	351	Q9HD23
GGSEMVILIAMGFDR	OR4F17	101	Q8NGA8
AALDMPFTLLGVMRG	GPR78	56	Q96P69
MSPAGMLRGDFSLRL	ICOSLG	86	O75144
TLLMLMGAAGLAGIR	OTOP1	356	Q7RTM1
GGLRAATVTLMLAML	HLA-DQB1	11	P01920
RLRTLGMGSFGRVML	PRKACG	46	P22612
MALRAGLVLGFHTLM	HLA-DOA	1	P06340
GIILLLATMATAFMG	MT-CYB	116	P00156
MRMAVIGGAIFLLAG	CLDN1	116	O95832
VSFMVDARGGSMRGS	ANK3	986	Q12955
MSLGVEGFAGVMVRA	ALOX12B	456	O75342
TLMMLGRFREALGDA	DNAJC7	71	Q99615
AGAFEMLIVGRFIMG	SLC2A9	161	Q9NRM0
MAFTDLLDALGSMGR	SLC22A20P	1	A6NK97
DALGTGARIGMMRTA	NEURL4	826	Q96JN8
SALSLMLPMGIGDRG	PRDM4	66	Q9UKN5
MGVGTLMGSGLRKLS	ABCB8	306	Q9NUT2
GGSEMVILIAMGFDR	OR4F4	101	Q96R69
MGLSNPFRGLMKLGT	PLEKHM1	526	Q9Y4G2
AVSGAMGLGFLLSML	SLC4A11	641	Q8NBS3
ETSGGMFVGLMAFLL	TMEM43	31	Q9BTV4
TAGFMGMAVAIILFG	TMEM178B	171	H3BS89
FFLMLLAMGLSSAIG	SLC6A16	501	Q9GZN6
LALGMLAGAATGMAL	PLEKHB2	201	Q96CS7
GIFAALAMLLSMASG	SLC29A2	171	Q14542
ALLMDRIGRLTMLGG	SV2C	601	Q496J9
RIGRLTMLGGSMVLS	SV2C	606	Q496J9
LGMMAGAFILGGLAD	SV2B	156	Q7L1I2
MMGLTEGVFLILSGT	TAS2R3	1	Q9NYW6
SMVQSLFMAGSLLGG	SLC22A24	146	Q8N4F4
SGLLSTFGGSTGRMM	PLCE1	481	Q9P212
SCLRIGMRGRELMGG	ROMO1	41	P60602
MSGYDRMLRTLGGNL	GUCY1B2	1	O75343
GAKGIRTLLFALMMS	SCN9A	1626	Q15858
FLGAVMPRLGIGMDT	SEPHS1	56	P49903
MLFVGLMRFATVVLG	SLC35E2A	146	P0CK97
AVAFGSGALMLGMFV	SLC26A10	121	Q8NG04
RKLMQGMGLGLSSVF	SLC17A9	311	Q9BYT1
FAMIRGGHVDLTMLG	OXCT1	386	P55809
GFHSMIMRSLGGILV	SLCO1B7	526	G3V0H7
NAIMGSGILGLSYAM	SLC38A4	86	Q969I6
GFPGSLSMRAAMFLI	OR6B1	16	O95007
MQMRLRSGGTEGLLA	SRP68	261	Q9UHB9
LRMAGRSPSFLEMLG	PNMA6A	306	P0CW24
GMLLGFGIMLLISIF	SLC39A6	731	Q13433
RFGMAAALAGTMRGI	ACADVL	341	P49748
GAAFGRLVGEIMAML	CLCN1	491	P35523
AALGMLFGGILMKRF	SLCO2A1	376	Q92959
LATSGTLAGIMGMRF	TMEM14C	66	Q9P0S9
FFIIMSMAGGTGSGL	TUBD1	136	Q9UJT1
LGMLRNGGLLFRMTL	TMTC4	261	Q5T4D3
FRMTLLTSGGAGMLY	TMTC4	271	Q5T4D3
GATMLIMDFIVAAGR	RALGAPA1	1206	Q6GYQ0
GMGSRLSNGEVMRGI	MPDZ	1171	O75970
MFRFPMGLLLGSVLL	TNN	6	Q9UQP3
MGMLAGAATGAALGS	PLEKHB1	221	Q9UF11
AMGFQSMVIRTLGGI	SLCO1B3	571	Q9NPD5
LLMAEMSRLVRGGSG	VCL	996	P18206
MARRAGGARMFGSLL	NMB	1	P08949
AMLIGILHMRSSFSG	TEX10	651	Q9NXF1
MLGALYMRLTGTAID	PRPF38A	101	Q8NAV1
MLFVGLMRFATVVLG	SLC35E2B	146	P0CK96
PLSLILMVFGGMTGF	TMEM114	111	B3SHH9
LMVFGGMTGFLSFLL	TMEM114	116	B3SHH9
RLTVLAGAMLALGLM	TMEM165	126	Q9HC07
SMKIILGGSMARVGA	THBS3	186	P49746
KMSLSVLEGMGFRVG	TRAPPC6A	31	O75865
MFFMVLVALVGLGLG	FASLG	86	P48023
YGLLVTLAMALMGGI	RHCG	396	Q9UBD6
AMVGSAAMGGILLAL	TIMM17A	111	Q99595
RLAAFMGITMLVGIT	ZDHHC21	181	Q8IVQ6
RNMESIGLGMARTGG	UPK2	141	O00526
MAAMAVALRGLGGRF	TXNRD2	1	Q9NNW7
IMIGMVSFGSGALLL	SLC46A2	351	Q9BY10
LISGVGIFMMGAGLS	SLC30A9	311	Q6PML9
IFLILRGVLGSTAMM	SLC35G1	131	Q2M3R5
DLDSLMMGSGSGRFG	TLDC2	161	A0PJX2
VLVGAGALMMAVGFF	TSPAN2	61	O60636
AELMRSMGLPLQFGR	TGS1	91	Q96RS0
SGMFRGLDGLRTLML	SLIT1	606	O75093
RAAAGGLAMLTSMRP	UNC45A	836	Q9H3U1
MGFGFLSMTARAGVA	LIN28A	51	Q9H9Z2
METLLGGLLAFGMAF	LRFN2	1	Q9ULH4