Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ZINC_FINGER_C2H2_2	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF512B ZNF425 ZNF735 ZNF506 ZNF479 PLAG1 ZNF841 ZNF839 PRDM16	9.33e-07	775	149	21	PS50157
Domain	ZINC_FINGER_C2H2_1	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF512B ZNF425 ZNF735 ZNF506 ZNF479 PLAG1 ZNF841 ZNF839 PRDM16	9.72e-07	777	149	21	PS00028
Domain	Znf_C2H2-like	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF512B ZNF425 ZNF735 ZNF506 ZNF479 PLAG1 ZNF841 ZNF839 PRDM16	1.43e-06	796	149	21	IPR015880
Domain	Znf_C2H2	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF512B ZNF425 ZNF735 ZNF506 ZNF479 PLAG1 ZNF841 ZNF839 PRDM16	1.71e-06	805	149	21	IPR007087
Domain	ZnF_C2H2	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF512B ZNF425 ZNF735 ZNF506 ZNF479 PLAG1 ZNF841 ZNF839 PRDM16	1.81e-06	808	149	21	SM00355
Domain	-	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF425 ZNF735 ZNF506 ZNF479 PLAG1 ZNF841 PRDM16	2.02e-06	679	149	19	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF425 ZNF735 ZNF506 ZNF479 PLAG1 ZNF841 PRDM16	2.78e-06	694	149	19	IPR013087
Domain	zf-C2H2	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF425 ZNF735 ZNF506 ZNF479 ZNF841 PRDM16	1.07e-05	693	149	18	PF00096
Domain	zf-C2H2_6	ZNF765 ZNF573 ZNF658 ZNF521 ZNF865 ZNF425 ZNF735 ZNF506 ZNF479 ZNF841 PRDM16	4.48e-05	314	149	11	PF13912
Domain	Rap_GAP	SIPA1L3 RALGAPA2 SIPA1L2	5.73e-05	10	149	3	PF02145
Domain	Tyr_Pase_non-rcpt_typ-14/21	PTPN21 PTPN14	6.32e-05	2	149	2	IPR014392
Domain	Rap_GAP_dom	SIPA1L3 RALGAPA2 SIPA1L2	7.83e-05	11	149	3	IPR000331
Domain	RAPGAP	SIPA1L3 RALGAPA2 SIPA1L2	7.83e-05	11	149	3	PS50085
Domain	Shal-type_N	KCND2 KCND3	1.89e-04	3	149	2	IPR021645
Domain	K_chnl_volt-dep_Kv4_C	KCND2 KCND3	1.89e-04	3	149	2	IPR024587
Domain	DUF3399	KCND2 KCND3	1.89e-04	3	149	2	PF11879
Domain	SPAR_C	SIPA1L3 SIPA1L2	1.89e-04	3	149	2	PF11881
Domain	K_chnl_volt-dep_Kv4	KCND2 KCND3	1.89e-04	3	149	2	IPR003975
Domain	Shal-type	KCND2 KCND3	1.89e-04	3	149	2	PF11601
Domain	SIPA1L_C	SIPA1L3 SIPA1L2	1.89e-04	3	149	2	IPR021818
Domain	RecQ_Zn_bind	WRN RECQL5	3.75e-04	4	149	2	PF16124
Domain	RecQ_Zn-bd	WRN RECQL5	3.75e-04	4	149	2	IPR032284
Domain	P-loop_NTPase	ABCA4 ERCC6 MYO9B ARL11 SPEF2 WRN BMS1 IFI44 RNF213 CHST1 NLRP3 DAP3 RECQL5 MOV10L1 KIF14 MYO18B CDC6	4.37e-04	848	149	17	IPR027417
Domain	KRAB	ZNF765 ZNF573 ZNF658 ZNF223 ZNF112 ZNF230 ZNF425 ZNF735 ZNF506 ZNF479	6.11e-04	358	149	10	PS50805
Domain	KRAB	ZNF765 ZNF573 ZNF658 ZNF223 ZNF112 ZNF230 ZNF425 ZNF735 ZNF506 ZNF479	6.11e-04	358	149	10	PF01352
Domain	GST_alpha	GSTA1 GSTA2	6.22e-04	5	149	2	IPR003080
Domain	DNA_helicase_ATP-dep_RecQ	WRN RECQL5	6.22e-04	5	149	2	IPR004589
Domain	KRAB	ZNF765 ZNF573 ZNF658 ZNF223 ZNF112 ZNF230 ZNF425 ZNF735 ZNF506 ZNF479	7.71e-04	369	149	10	SM00349
Domain	Sushi	CR1L C4BPB SRPX CSMD1	7.82e-04	52	149	4	PF00084
Domain	KRAB	ZNF765 ZNF573 ZNF658 ZNF223 ZNF112 ZNF230 ZNF425 ZNF735 ZNF506 ZNF479	7.87e-04	370	149	10	IPR001909
Domain	FERM_CS	PTPN21 FARP2 PTPN14	8.91e-04	24	149	3	IPR019747
Domain	CCP	CR1L C4BPB SRPX CSMD1	9.03e-04	54	149	4	SM00032
Domain	HELP	EML6 EML5	9.29e-04	6	149	2	PF03451
Domain	HELP	EML6 EML5	9.29e-04	6	149	2	IPR005108
Domain	SUSHI	CR1L C4BPB SRPX CSMD1	1.04e-03	56	149	4	PS50923
Domain	Sushi_SCR_CCP_dom	CR1L C4BPB SRPX CSMD1	1.11e-03	57	149	4	IPR000436
Domain	FERM_C	PTPN21 FARP2 PTPN14	1.13e-03	26	149	3	PF09380
Domain	FERM_PH-like_C	PTPN21 FARP2 PTPN14	1.26e-03	27	149	3	IPR018980
Domain	FERM_C	PTPN21 FARP2 PTPN14	1.26e-03	27	149	3	SM01196
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZNF628 MYO9B POLE SIPA1L3 TRMT11 RALGAPA2 ZNF865 BIRC6 CDR2L PLEKHG1 STK10 FAM83F MTOR NISCH PITX1 PLEC SIPA1L2 ARRDC2 ZNF839 PRDM16 ARAP1	2.14e-08	1105	154	21	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ERCC6 KDM5A RNF213 RALGAPA2 WDR26 ZNF512B DAP3 MFAP1 SETDB1 SULF2 PTPN14 EML5 CRYBG3 CSMD1 SIPA1L2 CDC27 PRDM16 ANKRD52 SLC4A11	5.67e-07	1116	154	19	31753913
Pubmed	Transcriptional regulation of P450scc gene expression in the embryonic rodent nervous system.	SP1 SP4 CYP11A1	1.69e-06	6	154	3	14576192
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	AHCYL1 SPAG1 NOP56 ZNF658 KDM5A COL20A1 SYNE1 SPEF2 SIPA1L3 BIVM EML6 APOB PTPN21 DAP3 MFAP1 LIG4 TKT PLEC SIPA1L2 CDC27 SLC4A11	1.70e-06	1442	154	21	35575683
Pubmed	POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1.	SP1 SP4 ADH5	2.94e-06	7	154	3	12004059
Pubmed	Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.	SP1 SP4 CYP11A1	4.69e-06	8	154	3	14988733
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SPAG1 RMND5A WRN WDR26 EXOSC2 CDR2L MFAP1 SETDB1 PTPN14 IFT52 GLA EML5 MTOR USH1G NISCH COPS4 COL14A1 PLEC CDC27	6.61e-06	1321	154	19	27173435
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 RALGAPA2 BIRC6 ZNF512B PLEKHG1 SULF2	6.86e-06	103	154	6	10574462
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ANGPT1 BAZ2B SIPA1L3 RNF213 RALGAPA2 BIRC6 FARP2 FAT2 POP1 SCIN PRDM16	1.35e-05	493	154	11	15368895
Pubmed	Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism.	RMND5A WDR26	1.95e-05	2	154	2	38759627
Pubmed	Polymorphism of human Alpha class glutathione transferases.	GSTA1 GSTA2	1.95e-05	2	154	2	11668220
Pubmed	Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA.	GSTA1 GSTA2	1.95e-05	2	154	2	3800996
Pubmed	Suppression of viral replication by drs tumor suppressor via mTOR dependent pathway.	MTOR SRPX	1.95e-05	2	154	2	21983129
Pubmed	Nucleotide sequence of the human liver glutathione S-transferase subunit 1 cDNA.	GSTA1 GSTA2	1.95e-05	2	154	2	3678589
Pubmed	Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133+ cells.	PROM1 MTOR	1.95e-05	2	154	2	33764985
Pubmed	The basic glutathione S-transferases from human livers are products of separate genes.	GSTA1 GSTA2	1.95e-05	2	154	2	3036131
Pubmed	The extended catalysis of glutathione transferase.	GSTA1 GSTA2	1.95e-05	2	154	2	21163259
Pubmed	Human glutathione S-transferase A2 polymorphisms: variant expression, distribution in prostate cancer cases/controls and a novel form.	GSTA1 GSTA2	1.95e-05	2	154	2	15128049
Pubmed	Genetic correction of Werner syndrome gene reveals impaired pro-angiogenic function and HGF insufficiency in mesenchymal stem cells.	HGF WRN	1.95e-05	2	154	2	32320127
Pubmed	Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression.	GSTA1 GSTA2	1.95e-05	2	154	2	11692074
Pubmed	Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1.	SYNE1 CSMD1	1.95e-05	2	154	2	24387768
Pubmed	Mutations in the genes KCND2 and KCND3 encoding the ion channels Kv4.2 and Kv4.3, conducting the cardiac fast transient outward current (ITO,f), are not a frequent cause of long QT syndrome.	KCND2 KCND3	1.95e-05	2	154	2	15563876
Pubmed	Correlation between the methylation of SULF2 and WRN promoter and the irinotecan chemosensitivity in gastric cancer.	WRN SULF2	1.95e-05	2	154	2	24359226
Pubmed	Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.	KCND2 KCND3	1.95e-05	2	154	2	26196737
Pubmed	Genomic organisation and chromosomal localisation of two members of the KCND ion channel family, KCND2 and KCND3.	KCND2 KCND3	1.95e-05	2	154	2	10942109
Pubmed	Reduced expression of SP1 and SP4 transcription factors in peripheral blood mononuclear cells in first-episode psychosis.	SP1 SP4	1.95e-05	2	154	2	23941741
Pubmed	Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.	MTOR ROS1	1.95e-05	2	154	2	31053160
Pubmed	Evidence that glutathione S-transferases B1B1 and B2B2 are the products of separate genes and that their expression in human liver is subject to inter-individual variation. Molecular relationships between the B1 and B2 subunits and other Alpha class glutathione S-transferases.	GSTA1 GSTA2	1.95e-05	2	154	2	2604726
Pubmed	Intact piRNA pathway prevents L1 mobilization in male meiosis.	MOV10L1 TNR	1.95e-05	2	154	2	28630288
Pubmed	Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome Activation.	RALGAPA2 NLRP3	1.95e-05	2	154	2	31622786
Pubmed	Isolation of a cDNA clone and localization of human glutathione S-transferase 2 genes to chromosome band 6p12.	GSTA1 GSTA2	1.95e-05	2	154	2	3031680
Pubmed	Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus.	KCND2 KCND3	1.95e-05	2	154	2	34386734
Pubmed	[Coxsackie virus B3 (CVB3) triggers the activation of NLRP3 in mouse macrophages by activating nicotinamide adenine dinucleotide kinase 2 (NADK2)].	NADK2 NLRP3	1.95e-05	2	154	2	36631013
Pubmed	Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia.	SP1 SP4	1.95e-05	2	154	2	25175639
Pubmed	MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway.	MTOR MYO18B	1.95e-05	2	154	2	30390677
Pubmed	Hepatitis C virus promotes expression of the 3β-hydroxysterol δ24-reductase through Sp1.	SP1 DHCR24	1.95e-05	2	154	2	22431021
Pubmed	Predictive value for lymph node metastasis of epithelial-mesenchymal transition and cancer stem cell marker expression in early gastric cancer.	HGF PROM1	1.95e-05	2	154	2	28595915
Pubmed	Isolation and characterization of the human gene encoding Ito: further diversity by alternative mRNA splicing.	KCND2 KCND3	1.95e-05	2	154	2	9843794
Pubmed	Genetic variation and haplotype structures of the glutathione S-transferase genes GSTA1 and GSTA2 in Japanese colorectal cancer patients.	GSTA1 GSTA2	1.95e-05	2	154	2	21844655
Pubmed	LncRNA Gaplinc promotes the pyroptosis of vascular endothelial cells through SP1 binding to enhance NLRP3 transcription in atherosclerosis.	SP1 NLRP3	1.95e-05	2	154	2	35901931
Pubmed	Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation.	APOB MTOR	1.95e-05	2	154	2	17698027
Pubmed	The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells.	MTOR NCR1	1.95e-05	2	154	2	24973821
Pubmed	Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate specificities.	GSTA1 GSTA2	1.95e-05	2	154	2	3138230
Pubmed	Heterologous expression of recombinant human glutathione transferase A1-1 from a hepatoma cell line.	GSTA1 GSTA2	1.95e-05	2	154	2	1330133
Pubmed	Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapses.	KCND2 KCND3	1.95e-05	2	154	2	17122053
Pubmed	NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis.	CD247 NCR1	1.95e-05	2	154	2	9625766
Pubmed	mTOR regulates NLRP3 inflammasome activation via reactive oxygen species in murine lupus.	NLRP3 MTOR	1.95e-05	2	154	2	30060081
Pubmed	The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.	GSTA1 GSTA2	1.95e-05	2	154	2	19639209
Pubmed	Characterization of two novel subunits of the alpha-class glutathione S-transferases of human liver.	GSTA1 GSTA2	1.95e-05	2	154	2	8431482
Pubmed	Molecular diagnosis of putative Stargardt disease by capture next generation sequencing.	ABCA4 PROM1	1.95e-05	2	154	2	24763286
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	GPD2 NOP56 KDM5A SYNE1 BCKDK BMS1 ZNF521 EXOSC2 ZNF512B DAP3 MFAP1 SULF2 SRPX PLEC SIPA1L2 GNS	2.66e-05	1082	154	16	38697112
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	AHCYL1 NOP56 SYNE1 POLE BCKDK BMS1 ZNF512B PLEKHG1 DAP3 MFAP1 PTPN14 NISCH POP1 COPS4 ROBO1 COL14A1 CRYBG3 SIPA1L2 ANKRD52	3.40e-05	1487	154	19	33957083
Pubmed	miR-99a-5p: A Potential New Therapy for Atherosclerosis by Targeting mTOR and Then Inhibiting NLRP3 Inflammasome Activation and Promoting Macrophage Autophagy.	NLRP3 MTOR	5.83e-05	3	154	2	35968506
Pubmed	HGF and SDF-1-mediated mobilization of CD133+ BMSC for hepatic regeneration following extensive liver resection.	HGF PROM1	5.83e-05	3	154	2	23701640
Pubmed	Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits.	KCND2 KCND3	5.83e-05	3	154	2	20371829
Pubmed	Toll-like receptor 3 controls QT interval on the electrocardiogram by targeting the degradation of Kv4.2/4.3 channels in the endoplasmic reticulum.	KCND2 KCND3	5.83e-05	3	154	2	30758987
Pubmed	Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts.	ANGPT1 PROM1	5.83e-05	3	154	2	22558265
Pubmed	Role of heteromultimers in the generation of myocardial transient outward K+ currents.	KCND2 KCND3	5.83e-05	3	154	2	11909823
Pubmed	Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene.	SP1 SP4	5.83e-05	3	154	2	11532028
Pubmed	Follistatin-like protein 1 enhances NLRP3 inflammasome-mediated IL-1β secretion from monocytes and macrophages.	NLRP3 FSTL1	5.83e-05	3	154	2	24470197
Pubmed	Unique clustering of A-type potassium channels on different cell types of the main olfactory bulb.	KCND2 KCND3	5.83e-05	3	154	2	18371079
Pubmed	Phosphorylated Sp1 is the regulator of DNA-PKcs and DNA ligase IV transcription of daunorubicin-resistant leukemia cell lines.	SP1 LIG4	5.83e-05	3	154	2	24530422
Pubmed	[Expression of hepatocyte growth factor, transcription factor SP1, vascular endothelial growth factor and CD34 in serosa-infiltrative gastric cancer and their relations with defluxion of gastric cancer cell and prognosis].	HGF SP1	5.83e-05	3	154	2	19563076
Pubmed	Autoinflammatory gene mutations in Behçet's disease.	NLRP3 MVK	5.83e-05	3	154	2	17213252
Pubmed	Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.	WRN RECQL5	5.83e-05	3	154	2	26391948
Pubmed	The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.	EGLN1 MTOR	5.83e-05	3	154	2	28199842
Pubmed	Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.	CD247 MTOR	5.83e-05	3	154	2	19201859
Pubmed	I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity.	KCND2 KCND3	5.83e-05	3	154	2	22815518
Pubmed	Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins.	SP1 SP4	5.83e-05	3	154	2	15345676
Pubmed	RapGAPs in brain: multipurpose players in neuronal Rap signalling.	SIPA1L3 SIPA1L2	5.83e-05	3	154	2	20576033
Pubmed	Molecular genetic evaluation of NLRP3, MVK and TNFRSF1A associated periodic fever syndromes.	NLRP3 MVK	5.83e-05	3	154	2	31135083
Pubmed	A-type K+ channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons.	KCND2 KCND3	5.83e-05	3	154	2	22615428
Pubmed	Combination of blockade of endothelin signalling and compensation of IGF1 expression protects the retina from degeneration.	PROM1 MTOR	5.83e-05	3	154	2	38252153
Pubmed	Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3.	SP1 SP4	5.83e-05	3	154	2	7559627
Pubmed	Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression.	MYO9B ROBO1	5.83e-05	3	154	2	26529257
Pubmed	BRCT domain-containing protein TopBP1 functions in DNA replication and damage response.	POLE TOPBP1	5.83e-05	3	154	2	11395493
Pubmed	A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome.	ABCA4 NLRP3	5.83e-05	3	154	2	23840644
Pubmed	Combined mutation and rearrangement screening by quantitative PCR high-resolution melting: is it relevant for hereditary recurrent Fever genes?	NLRP3 MVK	5.83e-05	3	154	2	21124859
Pubmed	mTOR Driven Gene Transcription Is Required for Cholesterol Production in Neurons of the Developing Cerebral Cortex.	SP1 MTOR	5.83e-05	3	154	2	34204880
Pubmed	Analysis of Sp transcription factors in the postmortem brain of chronic schizophrenia: a pilot study of relationship to negative symptoms.	SP1 SP4	5.83e-05	3	154	2	23540600
Pubmed	Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells.	SP1 SP4	5.83e-05	3	154	2	26967243
Pubmed	Curcumin decreases specificity protein expression in bladder cancer cells.	SP1 SP4	5.83e-05	3	154	2	18593936
Pubmed	Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission.	ACOX1 PRDM16	5.83e-05	3	154	2	30511960
Pubmed	PGC-1α inhibits NLRP3 signaling through transcriptional activation of POP1 to alleviate inflammation and strengthen osteogenic differentiation of lipopolysaccharide-induced human periodontal stem cells.	NLRP3 POP1	5.83e-05	3	154	2	38763227
Pubmed	Large T-antigen up-regulates Kv4.3 K⁺ channels through Sp1, and Kv4.3 K⁺ channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II.	SP1 KCND3	5.83e-05	3	154	2	22023388
Pubmed	Comparative expression of two alpha class glutathione S-transferases in human adult and prenatal liver tissues.	GSTA1 GSTA2	5.83e-05	3	154	2	12093480
Pubmed	Analysis of NLRP3, MVK and TNFRSF1A variants in adult Greek patients with autoinflammatory symptoms.	NLRP3 MVK	5.83e-05	3	154	2	30418111
Pubmed	Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation.	SP1 PROM1	5.83e-05	3	154	2	22945648
Pubmed	mTOR/STAT-3 pathway mediates mesenchymal stem cell-secreted hepatocyte growth factor protective effects against lipopolysaccharide-induced vascular endothelial barrier dysfunction and apoptosis.	HGF MTOR	5.83e-05	3	154	2	30242894
Pubmed	Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells.	SP1 SP4	5.83e-05	3	154	2	21919647
Pubmed	Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging.	ERCC6 SETDB1	5.83e-05	3	154	2	31276581
Pubmed	Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA).	KCND2 KCND3	5.83e-05	3	154	2	10729221
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ERCC6 BAZ2B WRN TOPBP1 ZNF512B MFAP1 RECQL5	6.30e-05	222	154	7	37071664
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MYO9B TOPBP1 BLK SETDB1 PTPN14 RECQL5 KIF14 CRYBG3 SIPA1L2 SCIN ANKRD52	6.69e-05	588	154	11	38580884
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ANGPT1 SYNE1 SIPA1L3 BIRC6 SULF2 PRDM16 ARAP1	6.86e-05	225	154	7	12168954
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GPD2 SIPA1L3 BCKDK BMS1 RNF213 PTPN21 BIRC6 ADH5 ZNF512B PTPN14 KIF14 ROBO1 CRYBG3 SCIN ANKRD52	7.00e-05	1049	154	15	27880917
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	NOP56 ECM2 APOB POP1 KIF14 PLEC MYO18B SIPA1L2 ZNF839 DISP1	7.83e-05	496	154	10	31343991
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SYNE1 CDR2L FAT2 POP1 PLEC PRDM16 SLC4A5	8.76e-05	234	154	7	36243803
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ERCC6 KDM5A BAZ2B WRN TOPBP1 EXOSC2 ZNF512B DAP3 RECQL5 PITX1 CDC27	9.00e-05	608	154	11	36089195
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF223 ZNF112 ZNF230	9.18e-05	20	154	3	12743021
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SP1 ZNF765 SP4 ZNF138 ZNF573 ZNF628 ZNF658 ZNF521 ZNF223 ZNF112 ZNF230 ZNF865 ZNF425 ZNF735 ZNF506 ZNF479 PLAG1 ZNF841 PRDM16	3.86e-08	718	107	19	28
GeneFamily	RecQ like helicases	WRN RECQL5	3.43e-04	5	107	2	1049
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CR1L C4BPB SRPX CSMD1	3.60e-04	57	107	4	1179
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP1 SP4	1.22e-03	9	107	2	755
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	BAZ2B SETDB1	1.84e-03	11	107	2	1025
GeneFamily	Fibronectin type III domain containing	COL20A1 ROBO1 COL14A1 ROS1 TNR	2.62e-03	160	107	5	555
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTPN21 FARP2 PTPN14	3.23e-03	50	107	3	1293
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN21 PTPN14	4.99e-03	18	107	2	812
GeneFamily	Sulfatases	SULF2 GNS	4.99e-03	18	107	2	410
Coexpression	GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	HGF B4GALT7 CYP11A1 SYNE1 CHST1 CD247 GLA MVK	4.88e-06	165	149	8	M9109
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANGPT1 SYNE1 ZNF521 PREX2 FSTL1 MOV10L1 COL14A1 SRPX	4.43e-07	197	154	8	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MXRA5 ANGPT1 ECM2 IFI44 SULF2 KCND3 COL14A1 SRPX	4.78e-07	199	154	8	fcbb3a9c0f4c5b4c1f09db24b9f50cc1166fa43b
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HGF ANGPT1 SYNE1 PREX2 FSTL1 ROBO1 COL14A1 SRPX	4.78e-07	199	154	8	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HGF MXRA5 ANGPT1 SYNE1 ADH5 FSTL1 COL14A1 SRPX	4.78e-07	199	154	8	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HGF ANGPT1 SYNE1 PREX2 ADH5 FSTL1 COL14A1 SRPX	4.96e-07	200	154	8	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HGF ANGPT1 SYNE1 ECM2 PREX2 FSTL1 COL14A1 SRPX	4.96e-07	200	154	8	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HGF ANGPT1 SYNE1 PREX2 ADH5 FSTL1 COL14A1 SRPX	4.96e-07	200	154	8	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ECM2 CLEC3A FSTL1 KCND2 PITX1 COL14A1 SRPX	3.04e-06	179	154	7	dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	HGF ANGPT1 ECM2 PREX2 ROBO1 COL14A1 CRYBG3	3.65e-06	184	154	7	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 SYNE1 PROM1 PTPN14 COL14A1 DISP1 SLC4A11	5.00e-06	193	154	7	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 SPEF2 CRTAC1 FREM2 ROS1 LRRC36 LRRC23	5.00e-06	193	154	7	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 NEK10 SYNE1 SPEF2 GSTA1 PROM1 LRRC23	5.72e-06	197	154	7	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 NEK10 SYNE1 SPEF2 GSTA1 PROM1 LRRC23	5.72e-06	197	154	7	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 NEK10 SYNE1 SPEF2 GSTA1 PROM1 LRRC23	5.72e-06	197	154	7	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 NEK10 SYNE1 SPEF2 GSTA1 PROM1 LRRC23	5.72e-06	197	154	7	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MXRA5 ECM2 SULF2 FSTL1 KCND3 COL14A1 SRPX	5.91e-06	198	154	7	e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HGF MXRA5 ANGPT1 ADH5 FSTL1 COL14A1 SRPX	6.11e-06	199	154	7	ba586690f88fd051f449753bfe7603a2cb431782
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HGF MXRA5 ANGPT1 ADH5 FSTL1 COL14A1 SRPX	6.11e-06	199	154	7	06a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCell	Biopsy_Other_PF-Mesenchymal-Myofibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	HGF MXRA5 ANGPT1 ECM2 FSTL1 ROBO1 COL14A1	6.31e-06	200	154	7	e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HGF ANGPT1 SYNE1 PREX2 FSTL1 ROBO1 COL14A1	6.31e-06	200	154	7	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BAZ2B SPEF2 ZNF521 RNF213 RALGAPA2 BIRC6 PREX2	6.31e-06	200	154	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / Treatment groups by lineage, cell group, cell type	ZNF521 CRTAC1 RALGAPA2 PREX2 ROBO1 PLEC GNS	6.31e-06	200	154	7	b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HGF ANGPT1 SYNE1 ADH5 FSTL1 COL14A1 SRPX	6.31e-06	200	154	7	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HGF ANGPT1 SYNE1 ADH5 FSTL1 COL14A1 SRPX	6.31e-06	200	154	7	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HGF ANGPT1 SYNE1 ADH5 FSTL1 COL14A1 SRPX	6.31e-06	200	154	7	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNE1 ECM2 ZNF521 PREX2 FSTL1 COL14A1 SRPX	6.31e-06	200	154	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HGF ANGPT1 ZNF521 FSTL1 KCND2 ROBO1 COL14A1	6.31e-06	200	154	7	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Biopsy_IPF-Mesenchymal\|Biopsy_IPF / Sample group, Lineage and Cell type	HGF MXRA5 ANGPT1 ECM2 FSTL1 COL14A1 SRPX	6.31e-06	200	154	7	bb605b373caf3f873dc1b87d712704568e0d6040
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	HGF ANGPT1 SYNE1 FSTL1 ROBO1 COL14A1 SRPX	6.31e-06	200	154	7	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	HGF MXRA5 ANGPT1 ECM2 FSTL1 ROBO1 COL14A1	6.31e-06	200	154	7	c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCell	droplet-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A4 ACOX1 APOB FAM83F DHCR24 C4BPB	1.15e-05	145	154	6	f142b86d4da5b71c189da46cbc4beebdc387ffee
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL20A1 NEK10 IFI44 APOB MTERF2 CDC27	1.74e-05	156	154	6	f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	EML6 GSTA1 PLEKHG1 ZNF425 ROBO1 COL14A1	2.30e-05	164	154	6	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD2 B4GALT7 CAPN3 BLK CD247 SIPA1L2	2.30e-05	164	154	6	b175258fb0885afd84d4a414c0ae441f880e8469
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD2 B4GALT7 CAPN3 BLK CD247 SIPA1L2	2.30e-05	164	154	6	875d922eec7e3df0998ddf0c8c4dee2dcd5b23ca
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD2 B4GALT7 CAPN3 BLK CD247 SIPA1L2	2.30e-05	164	154	6	8bcfc93220d7c99dddb32b7fa7fb9aec2a1c63fa
ToppCell	LPS-antiTNF-Epithelial_airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GSTA2 FREM2 PITX1 SCIN PRDM16 LRRC23	2.46e-05	166	154	6	eb942ed68677e55c46cb039046f45686d4062d7c
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 CYP11A1 BLK KCND2 KCND3 LRRC23	2.55e-05	167	154	6	e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPEF2 CHST1 BLK KCND3 SRPX TNR	2.91e-05	171	154	6	20ac3de9c164b409b70a30a8b6544ea491ef7c0e
ToppCell	metastatic_Brain-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	GPD2 TOPBP1 PTPN21 ZNF230 POP1 ZNF841	2.91e-05	171	154	6	0d14bc9688c427ba2265984987dc3eea195b19eb
ToppCell	CD8+_Memory_T_cell-FLU-3\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	IQCH ZNF658 POLE NLRP3 CDC6 ZNF839	3.01e-05	172	154	6	45ac433dbb3796f69e886c04457b2971403050ee
ToppCell	droplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP11A1 CAPN3 GSTA2 KIF14 NCR1 CDC6	3.11e-05	173	154	6	c399786aa25bdbe3394988db6955842b5b7e6b41
ToppCell	ASK452-Immune-B_cell\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	NADK2 ZNF521 FARP2 ZNF506 C4BPB ANKRD52	3.21e-05	174	154	6	69723f5666abc3af5f0431901a60246c9915ef81
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 CYP11A1 BLK KCND2 KCND3 LRRC23	3.31e-05	175	154	6	59249c9e83952d7277010e7be3c779e26399eb5d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 CYP11A1 BLK KCND2 KCND3 LRRC23	3.31e-05	175	154	6	b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 EML6 NIPAL3 PROM1 PTPN14 SLC4A11	3.53e-05	177	154	6	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPT1 COL20A1 NIPAL3 GSTA2 IFT52 ZNF839	3.65e-05	178	154	6	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	severe-Others-CD34+_GATA2+_cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ANGPT1 ZNF521 ZNF112 PROM1 FSTL1 HACD1	3.76e-05	179	154	6	dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 NEK10 SPEF2 GSTA1 PROM1 LRRC23	3.88e-05	180	154	6	adf5db5bfa9a38b1227ab0beccd8d6f3eea67ac0
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 FREM2 SULF2 TNR	4.13e-05	182	154	6	8a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 PROM1 SULF2 TNR	4.13e-05	182	154	6	a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 PROM1 SULF2 TNR	4.13e-05	182	154	6	831b5ce46b41efe01c4db6016c2f43148611373d
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 FREM2 SULF2 TNR	4.13e-05	182	154	6	e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	SYNE1 LMO7DN CRTAC1 FREM2 ROS1 LRRC36	4.25e-05	183	154	6	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IFI44 ZNF521 RNF213 PLEKHG1 SIPA1L2 LRRC36	4.25e-05	183	154	6	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A4 ZNF112 ACSF2 NIPAL3 PTPN14 SLC4A11	4.25e-05	183	154	6	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 APOB FREM2 ROBO1 ROS1 CSMD1	4.39e-05	184	154	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 APOB FREM2 ROBO1 ROS1 CSMD1	4.39e-05	184	154	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 APOB FREM2 ROBO1 ROS1 CSMD1	4.39e-05	184	154	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	RALGAPA2 PREX2 PLEKHG1 PTPN14 SRPX CSMD1	4.39e-05	184	154	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 PROM1 SULF2 TNR	4.52e-05	185	154	6	efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANGPT1 FSTL1 PITX1 COL14A1 SRPX ARAP1	4.52e-05	185	154	6	c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 PROM1 SULF2 TNR	4.52e-05	185	154	6	2e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	ZNF521 RALGAPA2 PLEKHG1 SULF2 PTPN14 OSBP2	4.52e-05	185	154	6	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 PROM1 SULF2 TNR	4.52e-05	185	154	6	7aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 PROM1 SULF2 TNR	4.52e-05	185	154	6	fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	ZNF521 RALGAPA2 PLEKHG1 SULF2 PTPN14 OSBP2	4.52e-05	185	154	6	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 PROM1 SULF2 TNR	4.80e-05	187	154	6	daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CRTAC1 FREM2 ROS1 SCIN LRRC36 LRRC23	4.80e-05	187	154	6	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PROM1 CLEC3A FSTL1 PITX1 ROBO1 COL14A1	4.80e-05	187	154	6	173f029dcf32af008f517912f6d110a33a9e98cf
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL20A1 IFI44 PREX2 PROM1 SULF2 TNR	4.80e-05	187	154	6	5b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	RALGAPA2 PREX2 PLEKHG1 SULF2 PTPN14 SRPX	4.94e-05	188	154	6	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	ZNF521 RALGAPA2 PREX2 PLEKHG1 SULF2 SRPX	4.94e-05	188	154	6	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IFI44 LMO7DN CRTAC1 PREX2 FREM2 COL14A1	4.94e-05	188	154	6	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF765 ABCA4 SLC38A4 ZNF521 RALGAPA2 CDC6	5.09e-05	189	154	6	0739baad9a7da511dd3d7249f84299aee88370a1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 FSTL1 COL14A1 SRPX PLEC SCIN	5.09e-05	189	154	6	562f8bf5a7d38afb4a8f2415d617d5f79cfb7e3f
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF2 FSTL1 COL14A1 SRPX PLEC SCIN	5.09e-05	189	154	6	270dd4a0fc5260288fe6829837942c78b40ecec4
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	IFI44 ZNF521 RALGAPA2 PREX2 PLEKHG1 SULF2	5.24e-05	190	154	6	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ABCA4 SLC38A4 ZNF521 CRTAC1 SULF2 PTPN14	5.24e-05	190	154	6	103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 EML6 CRTAC1 RECQL5 SCIN HACD1	5.24e-05	190	154	6	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	APOB FAT2 ZDHHC19 SLC4A5	5.54e-05	60	154	4	48adafeec1810bce5f118fa63d4a8ee7ab9ca0f7
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	APOB FAT2 ZDHHC19 SLC4A5	5.54e-05	60	154	4	a83afb89dbfc2e1cdfce57320d89c980bd8fb820
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SPAG1 NEK10 SYNE1 SPEF2 PROM1 LRRC23	5.55e-05	192	154	6	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MXRA5 IFI44 ZNF521 PLEKHG1 ROBO1 PRDM16	5.55e-05	192	154	6	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NEK10 GSTA1 GSTA2 PROM1 DHCR24 LRRC23	5.55e-05	192	154	6	03acd4a26b986e34eee608747347791122f1aa52
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NEK10 GSTA1 GSTA2 PROM1 DHCR24 LRRC23	5.55e-05	192	154	6	31c6046589e2fbb0486fd044c5b128099d37872f
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPEF2 ZNF521 PREX2 PLEKHG1 SIPA1L2 LRRC36	5.72e-05	193	154	6	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BAZ2B ZNF521 RALGAPA2 PLEKHG1 SIPA1L2 LRRC36	5.72e-05	193	154	6	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BAZ2B ZNF521 RALGAPA2 PLEKHG1 SIPA1L2 LRRC36	5.72e-05	193	154	6	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BAZ2B SPEF2 ZNF521 RALGAPA2 SIPA1L2 LRRC36	5.72e-05	193	154	6	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 PREX2 PROM1 NISCH SRPX ARAP1	5.72e-05	193	154	6	1b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SPAG1 NEK10 SYNE1 SPEF2 PROM1 LRRC23	5.72e-05	193	154	6	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 NEK10 SPEF2 GSTA1 PROM1 LRRC23	5.88e-05	194	154	6	3cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	HGF ECM2 ZNF521 FSTL1 COL14A1 SRPX	5.88e-05	194	154	6	2260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BAZ2B SPEF2 ZNF521 PREX2 PLEKHG1 SIPA1L2	5.88e-05	194	154	6	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HGF SYNE1 NLRP3 CDR2L NISCH PLAG1	5.88e-05	194	154	6	58046894446cb250814252a23f60fdd59c114d77
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 NEK10 SPEF2 GSTA1 PROM1 LRRC23	6.05e-05	195	154	6	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 PREX2 FSTL1 NISCH SRPX ARAP1	6.05e-05	195	154	6	b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 NEK10 SPEF2 GSTA1 PROM1 LRRC23	6.05e-05	195	154	6	d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF PREX2 KCND2 KCND3 COL14A1 SRPX	6.05e-05	195	154	6	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
Disease	fibrinogen measurement, tissue plasminogen activator measurement	CAPN3 NLRP3 FARP2 PLEC	7.13e-05	45	145	4	EFO_0004623, EFO_0004791
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	CAPN3 NLRP3 FARP2 PLEC	7.13e-05	45	145	4	EFO_0004623, EFO_0004792
Disease	Stargardt disease	ABCA4 PROM1	7.17e-05	3	145	2	cv:C0271093
Disease	Premature aging syndrome	ERCC6 WRN	1.43e-04	4	145	2	C0231341
Disease	aspartate aminotransferase measurement	SP4 ABCA4 RNF213 BIRC6 NLRP3 BLK ADH5 SETDB1 MTOR ROBO1 PLAG1 CSMD1 HACD1 MVK	1.55e-04	904	145	14	EFO_0004736
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	CAPN3 NLRP3 FARP2 PLEC	1.68e-04	56	145	4	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	fibrinogen measurement, factor VII measurement	CAPN3 NLRP3 ADH5 PLEC	1.93e-04	58	145	4	EFO_0004619, EFO_0004623
Disease	Liver carcinoma	HGF ACOX1 MTOR PITX1 KIF14 ROBO1 SRPX CDC6 CSMD1 MVK	2.14e-04	507	145	10	C2239176
Disease	STARGARDT DISEASE 1 (disorder)	ABCA4 PROM1	2.38e-04	5	145	2	C1855465
Disease	lipid metabolism disorder (is_implicated_in)	DHCR24 MVK	3.55e-04	6	145	2	DOID:3146 (is_implicated_in)
Disease	Stargardt's disease	ABCA4 PROM1	3.55e-04	6	145	2	C0271093
Disease	Aplasia Cutis Congenita	BMS1 PLEC	3.55e-04	6	145	2	C0282160
Disease	schizophrenia (implicated_via_orthology)	SP4 ZNF521 MTOR CSMD1	3.57e-04	68	145	4	DOID:5419 (implicated_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	MXRA5 SPEF2 WRN ACSF2 PREX2 KCND3 CSMD1 SIPA1L2 TNR	3.83e-04	447	145	9	EFO_0000694, MONDO_0100096
Disease	Hereditary Autoinflammatory Diseases	NLRP3 MVK	4.96e-04	7	145	2	C0751422
Disease	Large cell carcinoma of lung	MTOR ROS1 MYO18B	5.19e-04	32	145	3	C0345958
Disease	phenol sulfate measurement	PLEKHG1 MYO18B	6.59e-04	8	145	2	EFO_0021011
Disease	Sudden Cardiac Arrest	KCND2 KCND3	6.59e-04	8	145	2	C1720824
Disease	white matter hyperintensity measurement	AHCYL1 ANGPT1 ACOX1 SPEF2 PLEKHG1 RECQL5 PRDM16	7.61e-04	302	145	7	EFO_0005665
Disease	macrophage colony stimulating factor measurement	AHCYL1 PREX2 CSMD1	7.99e-04	37	145	3	EFO_0008217
Disease	lung cancer (implicated_via_orthology)	POLE ROBO1	8.44e-04	9	145	2	DOID:1324 (implicated_via_orthology)
Disease	retinal degeneration (is_implicated_in)	HGF ABCA4	8.44e-04	9	145	2	DOID:8466 (is_implicated_in)
Disease	response to carboplatin, response to antineoplastic agent	SPEF2 CSMD1	1.05e-03	10	145	2	GO_0097327, GO_0097328
Disease	high grade glioma (is_marker_for)	HGF SETDB1 MTOR	1.16e-03	42	145	3	DOID:3070 (is_marker_for)
Disease	polymyositis (is_marker_for)	HGF ROBO1	1.28e-03	11	145	2	DOID:0080745 (is_marker_for)
Disease	acute insulin response measurement	CHST1 ARAP1	1.28e-03	11	145	2	EFO_0006831
Disease	attention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia	SYNE1 IFI44 LIG4 CSMD1	1.58e-03	101	145	4	EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Disease	alcohol and nicotine codependence	PLEKHG1 KCND2	1.81e-03	13	145	2	EFO_0004776
Disease	Abnormality of refraction	GPD2 ABCA4 ANGPT1 KDM5A PKD1L1 CHST1 BIRC6 ROBO1 PLAG1 SLC4A11	1.87e-03	673	145	10	HP_0000539
Disease	treatment-resistant hypertension	ARL11 EML6 CHST1 TKT	2.09e-03	109	145	4	EFO_1002006
Disease	fibrinogen measurement	CAPN3 NLRP3 FARP2 PLEC	2.09e-03	109	145	4	EFO_0004623
Disease	Autosomal recessive limb-girdle muscular dystrophy	CAPN3 PLEC	2.10e-03	14	145	2	cv:C2931907
Disease	Testicular Germ Cell Tumor	STK10 PITX1	2.10e-03	14	145	2	C1336708
Disease	Opioid use measurement	KCND3 NCR1	2.41e-03	15	145	2	EFO_0009937
Disease	1,3,7-trimethylurate measurement	GSTA1 GSTA2	2.41e-03	15	145	2	EFO_0021172
Disease	anemia (implicated_via_orthology)	SLC4A5 SLC4A11	2.41e-03	15	145	2	DOID:2355 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	ABCA4 ERCC6 SYNE1 TRMT11 DAP3 SULF2 PTPN14 FAM83F MTOR NISCH POP1 ROBO1 CDC27	2.53e-03	1074	145	13	C0006142
Disease	Ischemic stroke, fibrinogen measurement	CAPN3 NLRP3 PLEC	2.53e-03	55	145	3	EFO_0004623, HP_0002140
Disease	Chronic Lymphocytic Leukemia	ARL11 TOPBP1 FARP2	2.53e-03	55	145	3	C0023434
Disease	Colorectal Carcinoma	ABCA4 ERCC6 SYNE1 POLE WRN APOB PREX2 PROM1 KCND3 NCR1	2.54e-03	702	145	10	C0009402
Disease	obsolete_red blood cell distribution width	SP1 MYO9B BAZ2B APOB CR1L BIRC6 NLRP3 GSTA2 PLEKHG1 STK10 COPS4 OSBP2 ZDHHC19 MVK LRRC23	2.66e-03	1347	145	15	EFO_0005192
Disease	Polydactyly	PROM1 FREM2 IFT52 PITX1	2.70e-03	117	145	4	C0152427
Disease	response to triptolide, cytotoxicity measurement	NEK10 CSMD1	2.75e-03	16	145	2	EFO_0006952, EFO_0007662
Disease	amygdala volume change measurement	PKD1L1 CSMD1	2.75e-03	16	145	2	EFO_0021490
Disease	body mass index, type 2 diabetes mellitus	MTOR ARAP1	2.75e-03	16	145	2	EFO_0004340, MONDO_0005148
Disease	Alzheimer disease	BCKDK CHST1 CDR2L PLEKHG1 LIG4 PLEC CSMD1 SIPA1L2	2.82e-03	485	145	8	MONDO_0004975
Disease	muscular dystrophy (is_implicated_in)	SYNE1 CAPN3	3.11e-03	17	145	2	DOID:9884 (is_implicated_in)
Disease	Moyamoya Disease	RNF213 GLA	3.11e-03	17	145	2	C0026654
Disease	dermatomyositis (is_marker_for)	HGF ROBO1	3.11e-03	17	145	2	DOID:10223 (is_marker_for)
Disease	colorectal health	ANGPT1 PKD1L1 STPG2 LIG4 CSMD1	3.22e-03	201	145	5	EFO_0008460
Disease	post-traumatic stress disorder	SP4 OSBP2 CSMD1 SIPA1L2 SLC4A5	3.29e-03	202	145	5	EFO_0001358
Disease	Age-related macular degeneration	ABCA4 ERCC6	3.48e-03	18	145	2	cv:C0242383
Disease	Chronic myeloproliferative disorder	LIG4 CDC6	3.88e-03	19	145	2	C1292778
Disease	Systemic Scleroderma	CD247 FSTL1	3.88e-03	19	145	2	C0036421
Disease	Headache	HGF RNF213 PRDM16	3.89e-03	64	145	3	HP_0002315
Disease	Severe Combined Immunodeficiency	LIG4 CD247	4.30e-03	20	145	2	C0085110
Disease	Schizophrenia	SP1 SP4 MYO9B PTPN21 GSTA1 SETDB1 EML5 FSTL1 MTOR OR4C46 CSMD1	4.34e-03	883	145	11	C0036341
Disease	ovarian neoplasm	ERCC6 ARL11 TRMT11 MTOR	4.39e-03	134	145	4	C0919267
Disease	Microcephaly	ERCC6 LIG4 KIF14	4.42e-03	67	145	3	C0025958
Disease	skin hydration measurement	PKD1L1 PLEKHG1	4.74e-03	21	145	2	EFO_0009586
Disease	Malignant neoplasm of ovary	ERCC6 ARL11 TRMT11 MTOR	4.74e-03	137	145	4	C1140680
Disease	electrocardiography	NEK10 PROM1 KCND3 TKT ROS1 PLEC MYO18B PRDM16	4.80e-03	530	145	8	EFO_0004327

Protein segments in the cluster

Peptide	Gene	Start	Entry
YSQATLHGTARGKTK	USH1G	201	Q495M9
KYEELLSKCRQHGAG	CDR2L	366	Q86X02
HQSNKGYSLASLLAK	BIRC6	1251	Q9NR09
HCKKGFYLLGSSALT	CSMD1	2826	Q96PZ7
RHIGKYLKQQTGLAT	CRYBG3	236	Q68DQ2
CLAGTYSGGNKRKLS	ABCA4	2066	P78363
GTSRFTCKGKTILHY	ADH5	126	P11766
YKAKTALGEHLLNVG	BAZ2B	1156	Q9UIF8
YRKTKKVGGNLHCII	BIVM	401	Q86UB2
AAQSLRSLHGTKYKV	CPA2	336	P48052
GIRQLANYVHSKGLK	GLA	116	P06280
GGLSYVQGCTKKHLN	ACSF2	56	Q96CM8
YRLYLKGHTGTAGKQ	ANGPT1	401	Q15389
CKDRKGYGLLHTAAA	ANKRD52	201	Q8NB46
LYAGRSQDGSHLLKS	BCKDK	76	O14874
SLYGYLRGAHLKNKS	BMS1	281	Q14692
LLRTCAKHYQNGTLG	DISP1	381	Q96F81
EGKHGSVRYCIKATL	ARRDC2	121	Q8TBH0
KSHGQDYLVGNKLSR	GSTA1	141	P08263
ELAHLYSTKSGGKRV	IQCH	601	Q86VS3
DSAGKTTLLYKLKGH	ARL11	21	Q969Q4
NLYACSKGVHLGLTS	ERCC6	631	P0DP91
TGNLYHRSIGKEIAK	KIF14	251	Q15058
LGLGHSYSRAKVKFN	NOP56	146	O00567
RVAKTGSSNAYLHSK	KCND3	431	Q9UK17
KNFGRSGRTKYTHLV	MFAP1	381	P55081
LNLQKYCHIRLAGSK	NIPAL3	51	Q6P499
STKLIHGGVRYLQKA	GPD2	111	P43304
ATHFYGTILLKNKGD	MOV10L1	256	Q9BXT6
LKEGRSSHVQRGYGK	NCR1	156	O76036
LALKGSSYSGLLERH	NADK2	101	Q4G0N4
KGKQGYVISLGHALS	LMO7DN	56	F2Z398
KQGRVSYAHNGDKSL	FREM2	896	Q5SZK8
GGILLLSKQHYRLCN	B4GALT7	201	Q9UBV7
KSHGQDYLVGNKLSR	GSTA2	141	P09210
CKTGNGLAHAYVKLE	LRRC23	61	Q53EV4
GCVYKVRKHSGQNLL	NEK10	531	Q6ZWH5
LCKKHLDSSYNLRVG	FAT2	2441	Q9NYQ8
CYSQTLSLHGSLGKR	LRRC36	336	Q1X8D7
YGVILHSLKNLSQKG	OR4A47	216	Q6IF82
THSLYGKKAILFNGC	OR4C46	81	A6NHA9
SGSHKDLAGKYRQIL	COPS4	16	Q9BT78
HSQGLRILGYTLKSC	KCND2	306	Q9NZV8
NYGGIKGKVSSRIHC	POLE	1921	Q07864
LRYRNKHICGGSLIK	HGF	511	P14210
YQSIGSTLKKLLHTG	RALGAPA2	106	Q2PPJ7
DGAVSLHTRSLKYGK	EXOSC2	151	Q13868
LHTRSLKYGKLGQGV	EXOSC2	156	Q13868
CGILLTSGARSYHLK	OSBP2	241	Q969R2
GKGTGSLLKSHYERI	KDM5A	151	P29375
KLNSSGYRIKDGHLA	MTERF2	336	Q49AM1
EGLRYGHKKSLSDAT	PTPN21	691	Q16825
VHCLSGKRQGSLVLY	POP1	281	Q99575
AQLITKGKCYGLHAF	ACOX1	191	Q15067
GEHTGQLYSKFLLKA	APOB	1921	P04114
YHSKNQGGKLAVLGS	IFT52	201	Q9Y366
QNHFGGKRLSLLYKG	IFI44	16	Q8TCB0
GKRLSLLYKGSVHGF	IFI44	21	Q8TCB0
ASGKLASKHLYIGGD	LIG4	606	P49917
KGHDGLYQGLSTATK	CD247	136	P20963
GVLLDAGKKSLTYFH	COL20A1	931	Q9P218
LLDAIKHISYKGGNT	COL14A1	1096	Q05707
DGSLYHKLREKLGCQ	DHCR24	486	Q15392
LVQHYSKKGDGLCQR	BLK	201	P51451
SVVTYHCNLGSRGKK	CR1L	181	Q2VPA4
HKRPVCGSNGKTYLN	FSTL1	61	Q12841
KGTHRGLYKSIQKTL	HACD1	101	B0YJ81
KGYHLVGKKTLFCNA	C4BPB	51	P20851
LREHICGKKAGSLYL	CDC6	186	Q99741
VLHRRIKKAGSGNYS	CYP11A1	181	P05108
RHCNGKLGSYKINGR	EGLN1	281	Q9GZT9
SSYNVLPGKKGHCLV	ECM2	91	O94769
LSINGKARKHGENYS	GNS	186	P15586
YTKKSGAHLRIIDGG	CRTAC1	466	Q9NQ79
KRVGICKGATSYITH	EML5	1116	Q05BV3
KRVGICKGASSYITH	EML6	1116	Q6ZMW3
QLSGYLLRKFKNSHG	FARP2	931	O94887
KLHGSYEALKGGNTT	CAPN3	211	P20807
LGHVYCKTDRLAKGS	CDC27	121	P30260
KHGLLGKAQLYLTVN	PKD1L1	1176	Q8TDX9
AKTIKELGGYLSNLH	FTH1P19	106	P0C7X4
YASLCGKSGRLALAH	MTOR	1656	P42345
HLYLRGNTLGDKGIK	NLRP3	916	Q96P20
LYGEKGTGKTLSLCH	DAP3	126	P51398
IRKLKQGHCTLGSYA	RTL5	241	Q5HYW3
RLKSKQHSSFGYGGL	PITX1	286	P78337
SGGCVLLHTSRKYLK	SLC4A11	86	Q8NBS3
KAFSSGYLLGEVLHK	SPEF2	26	Q9C093
IEGCGKVYGKTSHLR	SP4	651	Q02446
DYNTVHGLGKATRKN	TRMT11	246	Q7Z4G4
LEKVLHKFSGYGQLC	RMND5A	11	Q9H871
LDGILSKAQYHLKIG	SYNE1	1926	Q8NF91
KKGRGCSLQYQHATV	TMEM132B	556	Q14DG7
ITHFKGGYLKGLLTA	NXPE3	261	Q969Y0
VTGVHRLYQLSKAGK	AHCYL1	256	O43865
KYKAGGVASGLNHVL	SCIN	116	Q9Y6U3
RRHKKYTCGSVGAAL	PRDM16	246	Q9HAZ2
SDCKKNRGTYGTLHL	PROM1	561	O43490
YATTGLKVKHLLSGQ	PTPN14	1051	Q15678
QGLSFQHKIGILYCK	SIPA1L2	601	Q9P2F8
RKHKVGILYCKAGQS	SIPA1L3	621	O60292
TGELRKLNLSCGTYH	WRN	781	Q14191
YSVHLLLKTAKEGGS	SLC38A4	121	Q969I6
KGYELHGSSLLICQS	SRPX	91	P78539
QGCGKVYGKTSHLRA	SP1	631	P08047
IALETYKTGHGLRGK	RO60	326	P10155
KLINPKYALVSGCRH	FAM83F	321	Q8NEG4
IYGRHITGLCGKKQK	MRPS18C	91	Q9Y3D5
NKGKSLLSGNHIAYD	SETDB1	236	Q15047
HSGFLYKTASAGKLL	ARAP1	746	Q96P48
TLGKHKYGTVRNSAA	CHST1	341	O43916
GTKVHKKCYLASEGL	CLEC3A	71	O75596
CGKNYNTKLGFKRHL	PLAG1	126	Q6DJT9
CRGVNAKAYHAGLKA	RECQL5	281	O94762
QKYVDLGLGTHRVKC	RNF213	3126	Q63HN8
CGKSYSAPQSLLRHK	ZNF865	446	P0CJ78
SLQKVIPRTYGKCGH	ZNF735	106	P0CB33
KCGKSYITKSGLDLH	ZNF223	376	Q9UK11
GKAYSTGSNLIQHRK	ZNF573	476	Q86YE8
TLSRYGKYGHKNLQL	ZNF138	36	P52744
ATRKAYGQALAKLGH	TKT	316	P29401
GGALRYHQGKISSLK	MVK	211	Q03426
LKYKGIHFGNSSGRQ	STPG2	136	Q8N412
ALNYIHNGKKSRALS	ZNF521	591	Q96K83
VRGSNSCLHVGKEKY	SPAG1	131	Q07617
YKKSLHINGGGSAAE	STK10	821	O94804
YNKLSSLEGLHTKLG	NISCH	341	Q9Y2I1
KNCHRTNLNGKYGES	TNR	1301	Q92752
SKKECLSYGGRLLGN	SLC4A5	721	Q9BY07
RLKNSKASTDGHRYL	PREX2	281	Q70Z35
SGGNIYVLKVLACHS	ROS1	1626	P08922
HRKKRNGLTSTYAGI	ROBO1	921	Q9Y6N7
LNEYKGHLSGLAKRA	PLEC	911	Q15149
DGHKLGYCSKVQTGI	TAMM41	351	Q96BW9
YHLGAAGACKVGRKQ	MYO18B	831	Q8IUG5
TCEKSYIGKGGLARH	ZNF839	201	A8K0R7
SLQKVIPRTYGKCGH	ZNF479	106	Q96JC4
GKTFSQKSYLSGHER	ZNF658	776	Q5TYW1
CGKSYISRSGLTKHQ	ZNF841	766	Q6ZN19
LASCSKGAHLAGKYR	ZNF512B	771	Q96KM6
GKGFSKASTLLAHQR	ZNF112	671	Q9UJU3
KGYISKSGLNLHQRV	ZNF230	371	Q9UIE0
SADRTYKGKCRHLQG	ZDHHC19	221	Q8WVZ1
GKAYNCSSLLRKHQL	ZNF765	221	Q7L2R6
FTKRQAGHSKGSLYA	PLEKHG1	701	Q9ULL1
HLYNSLGRKGISAKS	PLEKHG1	1161	Q9ULL1
LGRKGISAKSQPYHR	PLEKHG1	1166	Q9ULL1
LKLLKTLEGHAYGVS	WDR26	391	Q9H7D7
GVHLYLSRKQCALKN	nan	16	Q6AWC8
CIRGSLKVHLYKHSG	ZNF425	676	Q6IV72
ASTHLILKERGGSKY	TOPBP1	691	Q92547
NYTLCRNGVKEKHGS	SULF2	171	Q8IWU5
NSGCYLDSGLGRKKI	TEX36	81	Q5VZQ5
HKRGYNGLKQCLATT	ZNF506	126	Q5JVG8
SLQKVIPRTYGKCGH	ZNF722	106	A0A1W2PQL4
GKTFSQKSYLSGHER	ZNF658B	536	Q4V348
KAFKGSSALLYHQRG	ZNF628	71	Q5EBL2
KSFKGSSGLRYHLRD	ZNF628	461	Q5EBL2
DKSHLKAGVQARLYG	MXRA5	2771	Q9NR99
GYTDNVGCIHLISKK	MYO9B	571	Q13459