| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | acetylcholine receptor regulator activity | SPDYE1 SPDYE11 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 3.63e-18 | 27 | 78 | 10 | GO:0030548 |
| GeneOntologyMolecularFunction | neurotransmitter receptor regulator activity | SPDYE1 SPDYE11 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 5.64e-18 | 28 | 78 | 10 | GO:0099602 |
| GeneOntologyMolecularFunction | protein kinase binding | SPDYE1 SPDYE11 AKT3 SPDYE17 RHOBTB1 SPDYE10 SPDYE15 SPDYE7P PIK3R1 PIK3R2 RHOBTB2 SPDYE3 SPDYE2 SPDYE8 SPDYE21 NBEA TRIM68 SPDYE5 SPDYE18 SPDYE12 SPDYE2B SPDYE4 SPDYE6 SPDYE14 SPDYE16 | 1.40e-15 | 873 | 78 | 25 | GO:0019901 |
| GeneOntologyMolecularFunction | kinase binding | SPDYE1 SPDYE11 AKT3 SPDYE17 RHOBTB1 SPDYE10 SPDYE15 SPDYE7P PIK3R1 PIK3R2 RHOBTB2 SPDYE3 SPDYE2 SPDYE8 SPDYE21 NBEA TRIM68 SPDYE5 SPDYE18 SPDYE12 SPDYE2B SPDYE4 SPDYE6 SPDYE14 SPDYE16 | 1.52e-14 | 969 | 78 | 25 | GO:0019900 |
| GeneOntologyMolecularFunction | ferroxidase activity | 1.14e-06 | 6 | 78 | 3 | GO:0004322 | |
| GeneOntologyMolecularFunction | oxidoreductase activity, acting on metal ions, oxygen as acceptor | 1.14e-06 | 6 | 78 | 3 | GO:0016724 | |
| GeneOntologyMolecularFunction | signaling receptor regulator activity | SPDYE1 BMP5 SPDYE11 INHBE SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 4.52e-06 | 616 | 78 | 12 | GO:0030545 |
| GeneOntologyMolecularFunction | 1-phosphatidylinositol-3-kinase activity | 9.25e-06 | 11 | 78 | 3 | GO:0016303 | |
| GeneOntologyMolecularFunction | 1-phosphatidylinositol-3-kinase regulator activity | 3.10e-05 | 16 | 78 | 3 | GO:0046935 | |
| GeneOntologyMolecularFunction | oxidoreductase activity, acting on metal ions | 4.49e-05 | 18 | 78 | 3 | GO:0016722 | |
| GeneOntologyMolecularFunction | intracellularly calcium-gated channel activity | 6.23e-05 | 20 | 78 | 3 | GO:0141147 | |
| GeneOntologyMolecularFunction | intracellularly calcium-gated chloride channel activity | 6.23e-05 | 20 | 78 | 3 | GO:0005229 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic ion channel activity | 1.09e-04 | 193 | 78 | 6 | GO:0015276 | |
| GeneOntologyMolecularFunction | ligand-gated channel activity | 1.22e-04 | 197 | 78 | 6 | GO:0022834 | |
| GeneOntologyMolecularFunction | phosphatidylinositol kinase activity | 1.40e-04 | 26 | 78 | 3 | GO:0052742 | |
| GeneOntologyMolecularFunction | copper ion binding | 2.47e-04 | 78 | 78 | 4 | GO:0005507 | |
| GeneOntologyMolecularFunction | lipid kinase activity | 5.49e-04 | 41 | 78 | 3 | GO:0001727 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic anion channel activity | 9.85e-04 | 50 | 78 | 3 | GO:0099095 | |
| GeneOntologyMolecularFunction | phosphotyrosine residue binding | 1.04e-03 | 51 | 78 | 3 | GO:0001784 | |
| GeneOntologyMolecularFunction | acetylcholine binding | 1.14e-03 | 13 | 78 | 2 | GO:0042166 | |
| GeneOntologyMolecularFunction | phosphatidylinositol 3-kinase regulatory subunit binding | 1.33e-03 | 14 | 78 | 2 | GO:0036312 | |
| GeneOntologyMolecularFunction | gated channel activity | 1.96e-03 | 334 | 78 | 6 | GO:0022836 | |
| GeneOntologyMolecularFunction | acetylcholine-gated monoatomic cation-selective channel activity | 1.97e-03 | 17 | 78 | 2 | GO:0022848 | |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | 2.10e-03 | 459 | 78 | 7 | GO:0005216 | |
| GeneOntologyMolecularFunction | protein phosphorylated amino acid binding | 2.50e-03 | 69 | 78 | 3 | GO:0045309 | |
| GeneOntologyMolecularFunction | kinase activity | 2.89e-03 | 764 | 78 | 9 | GO:0016301 | |
| GeneOntologyMolecularFunction | transferase activity, transferring phosphorus-containing groups | AKT3 NMNAT2 PIK3R1 CSNK2A1 PIK3R3 BUB1 KDR ATM CSNK2A3 TRRAP | 3.46e-03 | 938 | 78 | 10 | GO:0016772 |
| GeneOntologyMolecularFunction | acetylcholine receptor activity | 3.61e-03 | 23 | 78 | 2 | GO:0015464 | |
| GeneOntologyMolecularFunction | channel activity | 4.41e-03 | 525 | 78 | 7 | GO:0015267 | |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | 4.46e-03 | 526 | 78 | 7 | GO:0022803 | |
| GeneOntologyMolecularFunction | chloride channel activity | 4.65e-03 | 86 | 78 | 3 | GO:0005254 | |
| GeneOntologyBiologicalProcess | positive regulation of cyclin-dependent protein serine/threonine kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 5.20e-17 | 25 | 68 | 9 | GO:0045737 |
| GeneOntologyBiologicalProcess | positive regulation of cyclin-dependent protein kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 1.74e-16 | 28 | 68 | 9 | GO:1904031 |
| GeneOntologyBiologicalProcess | regulation of cyclin-dependent protein serine/threonine kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 2.75e-11 | 96 | 68 | 9 | GO:0000079 |
| GeneOntologyBiologicalProcess | regulation of cyclin-dependent protein kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 3.99e-11 | 100 | 68 | 9 | GO:1904029 |
| GeneOntologyBiologicalProcess | positive regulation of protein serine/threonine kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 1.40e-08 | 193 | 68 | 9 | GO:0071902 |
| GeneOntologyBiologicalProcess | positive regulation of kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 8.04e-07 | 405 | 68 | 10 | GO:0033674 |
| GeneOntologyBiologicalProcess | positive regulation of cell cycle | SPDYE1 SPDYE7P BUB1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 8.40e-07 | 407 | 68 | 10 | GO:0045787 |
| GeneOntologyBiologicalProcess | positive regulation of protein kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 2.15e-06 | 350 | 68 | 9 | GO:0045860 |
| GeneOntologyBiologicalProcess | phosphatidylinositol phosphate biosynthetic process | 2.56e-06 | 66 | 68 | 5 | GO:0046854 | |
| GeneOntologyBiologicalProcess | regulation of protein serine/threonine kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 2.59e-06 | 358 | 68 | 9 | GO:0071900 |
| GeneOntologyBiologicalProcess | positive regulation of protein phosphorylation | SPDYE1 SPDYE7P PIK3R1 PIK3R3 SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 3.83e-06 | 724 | 68 | 12 | GO:0001934 |
| GeneOntologyBiologicalProcess | positive regulation of transferase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 4.42e-06 | 490 | 68 | 10 | GO:0051347 |
| GeneOntologyBiologicalProcess | positive regulation of phosphorylation | SPDYE1 SPDYE7P PIK3R1 PIK3R3 SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 8.17e-06 | 780 | 68 | 12 | GO:0042327 |
| GeneOntologyBiologicalProcess | positive regulation of molecular function | TBC1D16 SPDYE1 SPDYE7P PLIN5 SPDYE3 SPDYE2 NLRP1 KDR TRIM68 SPDYE5 PLXND1 SPDYE2B SPDYE4 MTDH SPDYE6 SPDYE16 | 1.23e-05 | 1430 | 68 | 16 | GO:0044093 |
| GeneOntologyBiologicalProcess | positive regulation of catalytic activity | TBC1D16 SPDYE1 SPDYE7P PLIN5 SPDYE3 SPDYE2 NLRP1 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 2.65e-05 | 1028 | 68 | 13 | GO:0043085 |
| GeneOntologyBiologicalProcess | positive regulation of phosphate metabolic process | SPDYE1 SPDYE7P PIK3R1 PIK3R3 SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 2.68e-05 | 879 | 68 | 12 | GO:0045937 |
| GeneOntologyBiologicalProcess | positive regulation of phosphorus metabolic process | SPDYE1 SPDYE7P PIK3R1 PIK3R3 SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 2.68e-05 | 879 | 68 | 12 | GO:0010562 |
| GeneOntologyBiologicalProcess | copper ion transport | 3.75e-05 | 20 | 68 | 3 | GO:0006825 | |
| GeneOntologyBiologicalProcess | negative regulation of alcohol biosynthetic process | 4.37e-05 | 21 | 68 | 3 | GO:1902931 | |
| GeneOntologyBiologicalProcess | regulation of cell cycle | SPDYE1 SPDYE7P CSNK2A1 BUB1 SPDYE3 SPDYE2 ATM SPDYE5 CSNK2A3 SPDYE2B TRRAP SPDYE4 SPDYE6 SPDYE16 | 4.98e-05 | 1256 | 68 | 14 | GO:0051726 |
| GeneOntologyBiologicalProcess | positive regulation of protein modification process | SPDYE1 SPDYE7P PIK3R1 PIK3R3 SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 5.00e-05 | 937 | 68 | 12 | GO:0031401 |
| GeneOntologyBiologicalProcess | phosphatidylinositol-3-phosphate biosynthetic process | 5.05e-05 | 22 | 68 | 3 | GO:0036092 | |
| GeneOntologyBiologicalProcess | regulation of transferase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 KDR ATM SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 6.35e-05 | 810 | 68 | 11 | GO:0051338 |
| GeneOntologyBiologicalProcess | positive regulation of protein metabolic process | SPDYE1 SPDYE7P PIK3R1 CSNK2A1 PIK3R3 SPDYE3 SPDYE2 NLRP1 KDR SPDYE5 CSNK2A3 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 6.41e-05 | 1458 | 68 | 15 | GO:0051247 |
| GeneOntologyBiologicalProcess | phosphatidylinositol biosynthetic process | 7.51e-05 | 132 | 68 | 5 | GO:0006661 | |
| GeneOntologyBiologicalProcess | regulation of kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 7.90e-05 | 686 | 68 | 10 | GO:0043549 |
| GeneOntologyBiologicalProcess | negative regulation of steroid biosynthetic process | 1.59e-04 | 32 | 68 | 3 | GO:0010894 | |
| GeneOntologyBiologicalProcess | regulation of protein kinase activity | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 1.72e-04 | 611 | 68 | 9 | GO:0045859 |
| GeneOntologyBiologicalProcess | negative regulation of steroid metabolic process | 2.26e-04 | 36 | 68 | 3 | GO:0045939 | |
| GeneOntologyBiologicalProcess | phosphatidylinositol metabolic process | 2.46e-04 | 170 | 68 | 5 | GO:0046488 | |
| GeneOntologyBiologicalProcess | glycerolipid biosynthetic process | 2.54e-04 | 268 | 68 | 6 | GO:0045017 | |
| GeneOntologyBiologicalProcess | phospholipid biosynthetic process | 2.54e-04 | 268 | 68 | 6 | GO:0008654 | |
| GeneOntologyBiologicalProcess | organophosphate biosynthetic process | 2.54e-04 | 644 | 68 | 9 | GO:0090407 | |
| GeneOntologyBiologicalProcess | regulation of protein phosphorylation | SPDYE1 SPDYE7P PIK3R1 PIK3R3 SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 2.98e-04 | 1133 | 68 | 12 | GO:0001932 |
| GeneOntologyBiologicalProcess | lipid biosynthetic process | BMP5 SCAP PIK3R1 PIK3R2 PLIN5 CYP21A2 PIK3R3 IDI2 ATM INPP4B | 3.14e-04 | 813 | 68 | 10 | GO:0008610 |
| GeneOntologyBiologicalProcess | cell migration involved in sprouting angiogenesis | 3.21e-04 | 99 | 68 | 4 | GO:0002042 | |
| GeneOntologyBiologicalProcess | negative regulation of cholesterol biosynthetic process | 5.78e-04 | 11 | 68 | 2 | GO:0045541 | |
| GeneOntologyBiologicalProcess | negative regulation of sterol biosynthetic process | 5.78e-04 | 11 | 68 | 2 | GO:0106119 | |
| GeneOntologyBiologicalProcess | behavioral response to nicotine | 5.78e-04 | 11 | 68 | 2 | GO:0035095 | |
| GeneOntologyBiologicalProcess | regulation of phosphorylation | SPDYE1 SPDYE7P PIK3R1 PIK3R3 SPDYE3 SPDYE2 KDR SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 6.07e-04 | 1226 | 68 | 12 | GO:0042325 |
| GeneOntologyBiologicalProcess | membrane depolarization | 6.87e-04 | 121 | 68 | 4 | GO:0051899 | |
| GeneOntologyBiologicalProcess | negative regulation of cholesterol metabolic process | 6.92e-04 | 12 | 68 | 2 | GO:0090206 | |
| GeneOntologyBiologicalProcess | glycerophospholipid biosynthetic process | 7.49e-04 | 217 | 68 | 5 | GO:0046474 | |
| GeneOntologyBiologicalProcess | mineralocorticoid biosynthetic process | 8.16e-04 | 13 | 68 | 2 | GO:0006705 | |
| GeneOntologyCellularComponent | phosphatidylinositol 3-kinase complex, class I | 2.73e-06 | 9 | 68 | 3 | GO:0097651 | |
| GeneOntologyCellularComponent | phosphatidylinositol 3-kinase complex, class IA | 2.73e-06 | 9 | 68 | 3 | GO:0005943 | |
| GeneOntologyCellularComponent | protein kinase CK2 complex | 6.23e-05 | 4 | 68 | 2 | GO:0005956 | |
| GeneOntologyCellularComponent | phosphatidylinositol 3-kinase complex | 1.13e-04 | 29 | 68 | 3 | GO:0005942 | |
| GeneOntologyCellularComponent | transferase complex, transferring phosphorus-containing groups | 7.69e-04 | 335 | 68 | 6 | GO:0061695 | |
| Domain | Spy1 | SPDYE1 SPDYE3 SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 4.07e-21 | 11 | 69 | 9 | PF11357 |
| Domain | Speedy | SPDYE1 SPDYE3 SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 4.07e-21 | 11 | 69 | 9 | IPR020984 |
| Domain | PI3K_P85_iSH2 | 4.83e-08 | 3 | 69 | 3 | IPR032498 | |
| Domain | MULTICOPPER_OXIDASE2 | 4.83e-08 | 3 | 69 | 3 | PS00080 | |
| Domain | PI3K_P85_iSH2 | 4.83e-08 | 3 | 69 | 3 | PF16454 | |
| Domain | Cu-oxidase_2 | 1.93e-07 | 4 | 69 | 3 | IPR011706 | |
| Domain | Cu-oxidase_2 | 1.93e-07 | 4 | 69 | 3 | PF07731 | |
| Domain | Cu_oxidase_CS | 4.80e-07 | 5 | 69 | 3 | IPR033138 | |
| Domain | PI3kinase_P85 | 4.80e-07 | 5 | 69 | 3 | IPR001720 | |
| Domain | Cu-oxidase_3 | 4.80e-07 | 5 | 69 | 3 | IPR011707 | |
| Domain | MULTICOPPER_OXIDASE1 | 4.80e-07 | 5 | 69 | 3 | PS00079 | |
| Domain | Cu-oxidase_3 | 4.80e-07 | 5 | 69 | 3 | PF07732 | |
| Domain | Cu_oxidase_Cu_BS | 9.58e-07 | 6 | 69 | 3 | IPR002355 | |
| Domain | Cupredoxin | 1.19e-06 | 22 | 69 | 4 | IPR008972 | |
| Domain | - | 1.71e-05 | 14 | 69 | 3 | 2.60.40.420 | |
| Domain | Cu-oxidase | 4.03e-05 | 3 | 69 | 2 | PF00394 | |
| Domain | Cu-oxidase | 4.03e-05 | 3 | 69 | 2 | IPR001117 | |
| Domain | FAT | 2.00e-04 | 6 | 69 | 2 | PS51189 | |
| Domain | FATC | 2.00e-04 | 6 | 69 | 2 | PS51190 | |
| Domain | FAT | 2.00e-04 | 6 | 69 | 2 | PF02259 | |
| Domain | PIK-rel_kinase_FAT | 2.00e-04 | 6 | 69 | 2 | IPR003151 | |
| Domain | FATC_dom | 2.00e-04 | 6 | 69 | 2 | IPR003152 | |
| Domain | PIK_FAT | 2.00e-04 | 6 | 69 | 2 | IPR014009 | |
| Domain | FATC | 2.00e-04 | 6 | 69 | 2 | SM01343 | |
| Domain | Kinase-like_dom | 8.43e-04 | 542 | 69 | 8 | IPR011009 | |
| Domain | - | 1.56e-03 | 16 | 69 | 2 | 1.10.1070.11 | |
| Domain | Nicotinic_acetylcholine_rcpt | 1.56e-03 | 16 | 69 | 2 | IPR002394 | |
| Domain | PI3Kc | 1.56e-03 | 16 | 69 | 2 | SM00146 | |
| Domain | PI3/4_kinase_cat_dom | 1.98e-03 | 18 | 69 | 2 | IPR000403 | |
| Domain | PI3_PI4_kinase | 1.98e-03 | 18 | 69 | 2 | PF00454 | |
| Domain | PI3_4_KINASE_3 | 1.98e-03 | 18 | 69 | 2 | PS50290 | |
| Domain | PI3_4_KINASE_1 | 1.98e-03 | 18 | 69 | 2 | PS00915 | |
| Domain | PI3_4_KINASE_2 | 1.98e-03 | 18 | 69 | 2 | PS00916 | |
| Domain | RHO | 2.45e-03 | 20 | 69 | 2 | PS51420 | |
| Domain | - | 3.24e-03 | 23 | 69 | 2 | 1.20.120.370 | |
| Domain | Acetylcholine_rcpt_TM | 3.24e-03 | 23 | 69 | 2 | IPR027361 | |
| Domain | Rho_GTPase_activation_prot | 4.23e-03 | 88 | 69 | 3 | IPR008936 | |
| Domain | TGFb_propeptide | 4.78e-03 | 28 | 69 | 2 | PF00688 | |
| Domain | TGF-b_N | 4.78e-03 | 28 | 69 | 2 | IPR001111 | |
| Domain | TGF-beta-rel | 6.21e-03 | 32 | 69 | 2 | IPR015615 | |
| Domain | TGFb_CS | 6.21e-03 | 32 | 69 | 2 | IPR017948 | |
| Domain | SH2 | 6.21e-03 | 101 | 69 | 3 | PF00017 | |
| Pathway | KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY | 1.35e-08 | 9 | 47 | 4 | M47972 | |
| Pathway | KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY | 1.44e-07 | 15 | 47 | 4 | M47971 | |
| Pathway | WP_TRANSLATION_INHIBITORS_IN_CHRONICALLY_ACTIVATED_PDGFRA_CELLS | 4.10e-07 | 46 | 47 | 5 | M39805 | |
| Pathway | WP_BREAST_CANCER_PATHWAY | 7.06e-07 | 154 | 47 | 7 | M39739 | |
| Pathway | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | 7.59e-07 | 22 | 47 | 4 | M13897 | |
| Pathway | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | 9.17e-07 | 23 | 47 | 4 | MM14993 | |
| Pathway | KEGG_MEDICUS_REFERENCE_PDL_PD1_SHP_PI3K_SIGNALING_PATHWAY | 2.88e-06 | 9 | 47 | 3 | M47757 | |
| Pathway | WP_MELANOMA | 2.95e-06 | 68 | 47 | 5 | M39811 | |
| Pathway | REACTOME_CD28_CO_STIMULATION | 4.13e-06 | 33 | 47 | 4 | M11725 | |
| Pathway | REACTOME_CD28_CO_STIMULATION | 4.67e-06 | 34 | 47 | 4 | MM14992 | |
| Pathway | KEGG_VEGF_SIGNALING_PATHWAY | 5.12e-06 | 76 | 47 | 5 | M1749 | |
| Pathway | KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM | 5.12e-06 | 76 | 47 | 5 | M9052 | |
| Pathway | KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY | 7.91e-06 | 83 | 47 | 5 | M47961 | |
| Pathway | WP_EGFR_TYROSINE_KINASE_INHIBITOR_RESISTANCE | 8.39e-06 | 84 | 47 | 5 | M39839 | |
| Pathway | KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | 8.90e-06 | 85 | 47 | 5 | M3578 | |
| Pathway | KEGG_APOPTOSIS | 9.97e-06 | 87 | 47 | 5 | M8492 | |
| Pathway | PID_TCPTP_PATHWAY | 1.11e-05 | 42 | 47 | 4 | M91 | |
| Pathway | KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY | 1.11e-05 | 89 | 47 | 5 | M47963 | |
| Pathway | WP_CANCER_IMMUNOTHERAPY_BY_CTLA4_BLOCKADE | 1.23e-05 | 14 | 47 | 3 | M39840 | |
| Pathway | REACTOME_INTERLEUKIN_7_SIGNALING | 1.54e-05 | 15 | 47 | 3 | MM14536 | |
| Pathway | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | 2.23e-05 | 50 | 47 | 4 | MM14641 | |
| Pathway | WP_SYNAPTIC_SIGNALING_ASSOCIATED_WITH_AUTISM_SPECTRUM_DISORDER | 2.23e-05 | 50 | 47 | 4 | M39822 | |
| Pathway | WP_ALZHEIMERS_DISEASE | 2.30e-05 | 261 | 47 | 7 | M42565 | |
| Pathway | REACTOME_SIGNALING_BY_VEGF | 2.61e-05 | 106 | 47 | 5 | M27077 | |
| Pathway | KEGG_ENDOMETRIAL_CANCER | 2.61e-05 | 52 | 47 | 4 | M19877 | |
| Pathway | KEGG_MTOR_SIGNALING_PATHWAY | 2.61e-05 | 52 | 47 | 4 | M7561 | |
| Pathway | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | 2.82e-05 | 53 | 47 | 4 | M662 | |
| Pathway | KEGG_NON_SMALL_CELL_LUNG_CANCER | 3.04e-05 | 54 | 47 | 4 | M19818 | |
| Pathway | WP_DNA_DAMAGE_RESPONSE_ONLY_ATM_DEPENDENT | 3.12e-05 | 110 | 47 | 5 | M39492 | |
| Pathway | KEGG_ACUTE_MYELOID_LEUKEMIA | 3.76e-05 | 57 | 47 | 4 | M19888 | |
| Pathway | REACTOME_SIGNALING_BY_PDGFR_IN_DISEASE | 3.81e-05 | 20 | 47 | 3 | M29849 | |
| Pathway | REACTOME_SIGNALING_BY_KIT_IN_DISEASE | 3.81e-05 | 20 | 47 | 3 | M39002 | |
| Pathway | WP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA | 4.32e-05 | 59 | 47 | 4 | M39750 | |
| Pathway | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | 4.43e-05 | 21 | 47 | 3 | MM15633 | |
| Pathway | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | 5.12e-05 | 22 | 47 | 3 | M903 | |
| Pathway | REACTOME_INTERLEUKIN_RECEPTOR_SHC_SIGNALING | 5.12e-05 | 22 | 47 | 3 | MM15632 | |
| Pathway | KEGG_COLORECTAL_CANCER | 5.25e-05 | 62 | 47 | 4 | M14631 | |
| Pathway | WP_ENDOMETRIAL_CANCER | 5.59e-05 | 63 | 47 | 4 | M39623 | |
| Pathway | KEGG_GLIOMA | 6.33e-05 | 65 | 47 | 4 | M1835 | |
| Pathway | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | 6.72e-05 | 66 | 47 | 4 | MM14990 | |
| Pathway | REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS | 7.30e-05 | 313 | 47 | 7 | M27867 | |
| Pathway | WP_ACUTE_MYELOID_LEUKEMIA | 7.55e-05 | 68 | 47 | 4 | M48322 | |
| Pathway | WP_4HYDROXYTAMOXIFEN_DEXAMETHASONE_AND_RETINOIC_ACIDS_REGULATION_OF_P27_EXPRESSION | 7.59e-05 | 25 | 47 | 3 | M39574 | |
| Pathway | KEGG_RENAL_CELL_CARCINOMA | 8.46e-05 | 70 | 47 | 4 | M13266 | |
| Pathway | KEGG_PANCREATIC_CANCER | 8.46e-05 | 70 | 47 | 4 | M9726 | |
| Pathway | WP_MEASLES_VIRUS_INFECTION | 8.60e-05 | 136 | 47 | 5 | M42547 | |
| Pathway | REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING | 8.95e-05 | 71 | 47 | 4 | MM15590 | |
| Pathway | KEGG_MELANOMA | 8.95e-05 | 71 | 47 | 4 | M15798 | |
| Pathway | WP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS | 9.42e-05 | 326 | 47 | 7 | M39379 | |
| Pathway | WP_NONSMALL_CELL_LUNG_CANCER | 9.45e-05 | 72 | 47 | 4 | M39738 | |
| Pathway | REACTOME_INTERLEUKIN_RECEPTOR_SHC_SIGNALING | 9.61e-05 | 27 | 47 | 3 | M921 | |
| Pathway | KEGG_CHRONIC_MYELOID_LEUKEMIA | 9.97e-05 | 73 | 47 | 4 | M321 | |
| Pathway | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | 1.05e-04 | 74 | 47 | 4 | M17386 | |
| Pathway | PID_TRAIL_PATHWAY | 1.07e-04 | 28 | 47 | 3 | M79 | |
| Pathway | KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | 1.11e-04 | 75 | 47 | 4 | M5436 | |
| Pathway | REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING | 1.11e-04 | 75 | 47 | 4 | M27874 | |
| Pathway | REACTOME_PI_METABOLISM | 1.23e-04 | 77 | 47 | 4 | MM14590 | |
| Pathway | KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY | 1.36e-04 | 79 | 47 | 4 | M11816 | |
| Pathway | PID_NEPHRIN_NEPH1_PATHWAY | 1.46e-04 | 31 | 47 | 3 | M193 | |
| Pathway | WP_NONALCOHOLIC_FATTY_LIVER_DISEASE | 1.59e-04 | 155 | 47 | 5 | M39806 | |
| Pathway | WP_PI3KAKTMTOR_SIGNALING_AND_THERAPEUTIC_OPPORTUNITIES_IN_PROSTATE_CANCER | 1.61e-04 | 32 | 47 | 3 | M39445 | |
| Pathway | WP_GLIOBLASTOMA_SIGNALING | 1.64e-04 | 83 | 47 | 4 | M39637 | |
| Pathway | REACTOME_PI_METABOLISM | 1.72e-04 | 84 | 47 | 4 | M676 | |
| Pathway | KEGG_SMALL_CELL_LUNG_CANCER | 1.72e-04 | 84 | 47 | 4 | M3228 | |
| Pathway | KEGG_ERBB_SIGNALING_PATHWAY | 1.97e-04 | 87 | 47 | 4 | M12467 | |
| Pathway | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | 2.11e-04 | 35 | 47 | 3 | M127 | |
| Pathway | REACTOME_INTERLEUKIN_2_FAMILY_SIGNALING | 2.11e-04 | 35 | 47 | 3 | MM15144 | |
| Pathway | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 2.11e-04 | 35 | 47 | 3 | MM14512 | |
| Pathway | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 2.11e-04 | 35 | 47 | 3 | M773 | |
| Pathway | WP_PANCREATIC_ADENOCARCINOMA_PATHWAY | 2.15e-04 | 89 | 47 | 4 | M39732 | |
| Pathway | KEGG_PROSTATE_CANCER | 2.15e-04 | 89 | 47 | 4 | M13191 | |
| Pathway | REACTOME_SIGNALING_BY_LTK_IN_CANCER | 2.26e-04 | 7 | 47 | 2 | M48255 | |
| Pathway | REACTOME_INTERLEUKIN_7_SIGNALING | 2.30e-04 | 36 | 47 | 3 | M542 | |
| Pathway | WP_ERBB_SIGNALING | 2.44e-04 | 92 | 47 | 4 | M39715 | |
| Pathway | REACTOME_SIGNALING_BY_SCF_KIT | 2.49e-04 | 37 | 47 | 3 | MM14564 | |
| Pathway | REACTOME_RET_SIGNALING | 2.70e-04 | 38 | 47 | 3 | MM15493 | |
| Pathway | PID_FAS_PATHWAY | 2.70e-04 | 38 | 47 | 3 | M94 | |
| Pathway | PID_ERBB4_PATHWAY | 2.70e-04 | 38 | 47 | 3 | M13 | |
| Pathway | WP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION | 2.70e-04 | 38 | 47 | 3 | M39854 | |
| Pathway | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | 2.88e-04 | 96 | 47 | 4 | M16121 | |
| Pathway | WP_SMALL_CELL_LUNG_CANCER | 2.88e-04 | 96 | 47 | 4 | M39834 | |
| Pathway | REACTOME_PI3K_AKT_ACTIVATION | 3.01e-04 | 8 | 47 | 2 | MM14776 | |
| Pathway | REACTOME_RET_SIGNALING | 3.15e-04 | 40 | 47 | 3 | M27746 | |
| Pathway | WP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY | 3.15e-04 | 40 | 47 | 3 | M39695 | |
| Pathway | PID_ERBB1_INTERNALIZATION_PATHWAY | 3.39e-04 | 41 | 47 | 3 | M214 | |
| Pathway | REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING | 3.39e-04 | 41 | 47 | 3 | MM15162 | |
| Pathway | WP_RAS_SIGNALING | 3.53e-04 | 184 | 47 | 5 | M39764 | |
| Pathway | KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 3.63e-04 | 102 | 47 | 4 | M3261 | |
| Pathway | KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION | 3.64e-04 | 42 | 47 | 3 | M16473 | |
| Pathway | WP_TOLLLIKE_RECEPTOR_SIGNALING | 3.77e-04 | 103 | 47 | 4 | M39434 | |
| Pathway | REACTOME_SIGNALING_BY_VEGF | 3.77e-04 | 103 | 47 | 4 | MM14752 | |
| Pathway | REACTOME_PI3K_AKT_ACTIVATION | 3.86e-04 | 9 | 47 | 2 | M714 | |
| Pathway | REACTOME_RND2_GTPASE_CYCLE | 3.90e-04 | 43 | 47 | 3 | M41827 | |
| Pathway | PID_CXCR3_PATHWAY | 3.90e-04 | 43 | 47 | 3 | M222 | |
| Pathway | REACTOME_SIGNALING_BY_SCF_KIT | 3.90e-04 | 43 | 47 | 3 | M508 | |
| Pathway | REACTOME_INTERLEUKIN_2_FAMILY_SIGNALING | 4.18e-04 | 44 | 47 | 3 | M1012 | |
| Pathway | PID_ERBB2_ERBB3_PATHWAY | 4.18e-04 | 44 | 47 | 3 | M175 | |
| Pathway | REACTOME_RND2_GTPASE_CYCLE | 4.18e-04 | 44 | 47 | 3 | MM15678 | |
| Pathway | SIG_CHEMOTAXIS | 4.47e-04 | 45 | 47 | 3 | M5193 | |
| Pathway | KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 4.51e-04 | 108 | 47 | 4 | M9904 | |
| Pubmed | Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins. | SPDYE1 SPDYE17 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 5.75e-25 | 13 | 79 | 10 | 15611625 |
| Pubmed | Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene. | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 1.00e-24 | 9 | 79 | 9 | 36272447 |
| Pubmed | Characterization of a new family of cyclin-dependent kinase activators. | SPDYE1 SPDYE17 SPDYE7P SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE4 SPDYE6 SPDYE16 | 3.88e-23 | 17 | 79 | 10 | 15574121 |
| Pubmed | 1.13e-08 | 3 | 79 | 3 | 22763696 | ||
| Pubmed | 1.13e-08 | 3 | 79 | 3 | 24988611 | ||
| Pubmed | 4.50e-08 | 4 | 79 | 3 | 27616589 | ||
| Pubmed | The PI3K p110delta controls T-cell development, differentiation and regulation. | 4.50e-08 | 4 | 79 | 3 | 17371229 | |
| Pubmed | 1.12e-07 | 5 | 79 | 3 | 20200404 | ||
| Pubmed | 1.12e-07 | 5 | 79 | 3 | 35429500 | ||
| Pubmed | 1.75e-07 | 22 | 79 | 4 | 11994280 | ||
| Pubmed | The emerging mechanisms of isoform-specific PI3K signalling. | 2.24e-07 | 6 | 79 | 3 | 20379207 | |
| Pubmed | 2.24e-07 | 6 | 79 | 3 | 7542745 | ||
| Pubmed | Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK. | 3.92e-07 | 7 | 79 | 3 | 9178903 | |
| Pubmed | 6.27e-07 | 8 | 79 | 3 | 22402981 | ||
| Pubmed | Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase. | 6.27e-07 | 8 | 79 | 3 | 17846664 | |
| Pubmed | 6.27e-07 | 8 | 79 | 3 | 26037503 | ||
| Pubmed | 6.46e-07 | 30 | 79 | 4 | 38310234 | ||
| Pubmed | 9.38e-07 | 9 | 79 | 3 | 12470648 | ||
| Pubmed | 9.38e-07 | 9 | 79 | 3 | 21765914 | ||
| Pubmed | 1.34e-06 | 10 | 79 | 3 | 33773096 | ||
| Pubmed | 1.34e-06 | 10 | 79 | 3 | 9062339 | ||
| Pubmed | 1.84e-06 | 11 | 79 | 3 | 20598684 | ||
| Pubmed | 1.84e-06 | 11 | 79 | 3 | 25104021 | ||
| Pubmed | 2.45e-06 | 12 | 79 | 3 | 14602571 | ||
| Pubmed | 3.17e-06 | 13 | 79 | 3 | 9394803 | ||
| Pubmed | 4.03e-06 | 14 | 79 | 3 | 17157319 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 32895527 | ||
| Pubmed | Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy. | 5.09e-06 | 2 | 79 | 2 | 16227599 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 16679292 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 16679293 | ||
| Pubmed | Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD. | 5.09e-06 | 2 | 79 | 2 | 18326691 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 23221569 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 25788583 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 16239435 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 23077605 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 21109194 | ||
| Pubmed | Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2. | 5.09e-06 | 2 | 79 | 2 | 14646071 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 15365174 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 22406075 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 30060949 | ||
| Pubmed | Assignment of casein kinase 2 alpha sequences to two different human chromosomes. | 5.09e-06 | 2 | 79 | 2 | 1577469 | |
| Pubmed | Pan-cancer analysis on the role of PIK3R1 and PIK3R2 in human tumors. | 5.09e-06 | 2 | 79 | 2 | 35395865 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 29883959 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 31635307 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 20685892 | ||
| Pubmed | Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium. | 5.09e-06 | 2 | 79 | 2 | 22342521 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 17164340 | ||
| Pubmed | The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration. | 5.09e-06 | 2 | 79 | 2 | 21051716 | |
| Pubmed | The Placental Ferroxidase Zyklopen Is Not Essential for Iron Transport to the Fetus in Mice. | 5.09e-06 | 2 | 79 | 2 | 34114013 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 16488127 | ||
| Pubmed | Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit. | 5.09e-06 | 2 | 79 | 2 | 12860116 | |
| Pubmed | Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone. | 5.09e-06 | 2 | 79 | 2 | 26303407 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 18534979 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 29355933 | ||
| Pubmed | Established and novel Cdk/cyclin complexes regulating the cell cycle and development. | 5.09e-06 | 2 | 79 | 2 | 21630153 | |
| Pubmed | Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney. | 5.09e-06 | 2 | 79 | 2 | 27991585 | |
| Pubmed | Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase. | 5.09e-06 | 2 | 79 | 2 | 17071741 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 10459020 | ||
| Pubmed | Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangement. | 5.09e-06 | 2 | 79 | 2 | 15767666 | |
| Pubmed | Molecular cloning of the human casein kinase II alpha subunit. | 5.09e-06 | 2 | 79 | 2 | 2752008 | |
| Pubmed | Structure and sequence of an intronless gene for human casein kinase II-alpha subunit. | 5.09e-06 | 2 | 79 | 2 | 8420794 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 17065470 | ||
| Pubmed | Curly-whiskers and its linkage with tail-kinks in linkage group II of the mouse. | 5.09e-06 | 2 | 79 | 2 | 5911159 | |
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 31263155 | ||
| Pubmed | 5.09e-06 | 2 | 79 | 2 | 1314371 | ||
| Pubmed | HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45. | 6.18e-06 | 16 | 79 | 3 | 16524887 | |
| Pubmed | 6.18e-06 | 16 | 79 | 3 | 20818790 | ||
| Pubmed | 7.50e-06 | 17 | 79 | 3 | 23251686 | ||
| Pubmed | Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation. | 1.53e-05 | 3 | 79 | 2 | 15684395 | |
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 30182051 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 12588990 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 16006513 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 10097090 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 10627473 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 2174700 | ||
| Pubmed | Iron promotes oxidative cell death caused by bisretinoids of retina. | 1.53e-05 | 3 | 79 | 2 | 29686088 | |
| Pubmed | Class 1A PI3K regulates vessel integrity during development and tumorigenesis. | 1.53e-05 | 3 | 79 | 2 | 18621722 | |
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 12730242 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 27854409 | ||
| Pubmed | The Dictyostelium discoideum family of Rho-related proteins. | 1.53e-05 | 3 | 79 | 2 | 11222756 | |
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 1766873 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 19811262 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 25501707 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 18453570 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 21984976 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 7982920 | ||
| Pubmed | Atypical Rho GTPases of the RhoBTB Subfamily: Roles in Vesicle Trafficking and Tumorigenesis. | 1.53e-05 | 3 | 79 | 2 | 27314390 | |
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 16787925 | ||
| Pubmed | Crystallization and preliminary characterization of crystals of human protein kinase CK2. | 1.53e-05 | 3 | 79 | 2 | 11092945 | |
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 22493067 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 23640881 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 12102635 | ||
| Pubmed | The positions of the centromeres in linkage groups II and IX of the mouse. | 1.53e-05 | 3 | 79 | 2 | 5647630 | |
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 30825222 | ||
| Pubmed | Neither human hephaestin nor ceruloplasmin forms a stable complex with transferrin. | 1.53e-05 | 3 | 79 | 2 | 18022819 | |
| Pubmed | Mesothelin inhibits paclitaxel-induced apoptosis through the PI3K pathway. | 1.53e-05 | 3 | 79 | 2 | 19747165 | |
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 22729224 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 19286672 | ||
| Pubmed | 1.53e-05 | 3 | 79 | 2 | 12426103 | ||
| Pubmed | Uncommon GNAQ, MMP8, AKT3, EGFR, and PIK3R1 mutations in thyroid cancers. | 1.53e-05 | 3 | 79 | 2 | 21487925 | |
| Interaction | EIF4EBP1 interactions | 1.52e-05 | 94 | 67 | 5 | int:EIF4EBP1 | |
| Interaction | SPDYE3 interactions | 3.26e-05 | 3 | 67 | 2 | int:SPDYE3 | |
| Interaction | CYP27A1 interactions | 3.28e-05 | 19 | 67 | 3 | int:CYP27A1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr7q11 | SPDYE11 SPDYE17 SPDYE10 SPDYE13 SPDYE15 SPDYE7P SPDYE8 SPDYE21 SPDYE9 SPDYE5 SPDYE18 SPDYE12 SPDYE14 SPDYE16 | 5.70e-17 | 271 | 81 | 14 | chr7q11 |
| Cytoband | 7q11.23 | 4.62e-10 | 97 | 81 | 7 | 7q11.23 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr17p13 | 3.54e-05 | 346 | 81 | 6 | chr17p13 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr7q22 | 4.50e-05 | 219 | 81 | 5 | chr7q22 | |
| Cytoband | 7q22.1 | 5.00e-05 | 113 | 81 | 4 | 7q22.1 | |
| Cytoband | 17p13.1 | 1.22e-03 | 118 | 81 | 3 | 17p13.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr6q16 | 4.45e-03 | 56 | 81 | 2 | chr6q16 | |
| GeneFamily | Speedy/RINGO cell cycle regulator family | SPDYE1 SPDYE7P SPDYE3 SPDYE2 SPDYE8 SPDYE9 SPDYE5 SPDYE2B SPDYE4 SPDYE6 | 2.61e-25 | 12 | 46 | 10 | 756 |
| GeneFamily | Cholinergic receptors nicotinic subunits | 7.43e-04 | 16 | 46 | 2 | 173 | |
| GeneFamily | Rho family GTPases | 1.17e-03 | 20 | 46 | 2 | 390 | |
| GeneFamily | SH2 domain containing | 2.16e-03 | 101 | 46 | 3 | 741 | |
| ToppCell | droplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.44e-07 | 182 | 75 | 6 | dc55de945c6f78f32eb3a1b3520835eb8417e068 | |
| ToppCell | droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.44e-07 | 182 | 75 | 6 | 010a7364da46101cb5068891fd7bc712ea8f13bd | |
| ToppCell | droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.44e-07 | 182 | 75 | 6 | b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01 | |
| ToppCell | 367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells) | 1.07e-05 | 172 | 75 | 5 | da959c1abadafd79b7a0088a25eb8ef8efa3a0c2 | |
| ToppCell | 5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.26e-05 | 178 | 75 | 5 | 360d7a987f91d6d721487a921824057ec31a7332 | |
| ToppCell | droplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.33e-05 | 180 | 75 | 5 | dd1b10c7f5a0fbc63163844ca1882884a24a84d3 | |
| ToppCell | droplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.33e-05 | 180 | 75 | 5 | 423454e3390080ae03bb3cbb267255ebfe4df080 | |
| ToppCell | severe-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class | 1.87e-05 | 193 | 75 | 5 | 9337bc93e3904c7fc7c93c328518bcd6453b1e8c | |
| ToppCell | severe-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class | 2.06e-05 | 197 | 75 | 5 | 57ebd552f10d6278623b52a3d484d4b91ae1d028 | |
| ToppCell | Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 2.11e-05 | 198 | 75 | 5 | fab3135f03cf23a9f04f0eed543a9dc181f39f5f | |
| ToppCell | Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 2.21e-05 | 200 | 75 | 5 | b992eeddee38e6fe3564e9b1850f6b20b89bf47d | |
| Drug | Isoproterenol | 9.66e-07 | 7 | 70 | 3 | DB01064 | |
| Drug | CP-7 | 4.51e-06 | 11 | 70 | 3 | CID000451658 | |
| Drug | Nicorette | BMP5 PIK3R1 PIK3R2 CYP21A2 PIK3R3 LOXL4 NLRP1 KDR CHRNA5 CHRNB1 | 4.79e-06 | 529 | 70 | 10 | CID000000942 |
| Drug | CHEMBL459685 | 8.39e-06 | 42 | 70 | 4 | CID010995375 | |
| Drug | indiganylidynestibane | 9.32e-06 | 2 | 70 | 2 | CID003468413 | |
| Drug | 4-hydroxyisoleucine | 1.23e-05 | 15 | 70 | 3 | CID000354197 | |
| Drug | ZSTK474 | 1.83e-05 | 17 | 70 | 3 | CID011647372 | |
| Drug | MolPort-016-580-972 | 1.84e-05 | 51 | 70 | 4 | CID009938589 | |
| Drug | NVP-BEZ235 | 2.20e-05 | 18 | 70 | 3 | CID011977753 | |
| Drug | Tridihexethyl chloride; Down 200; 11.4uM; MCF7; HT_HG-U133A | 2.79e-05 | 192 | 70 | 6 | 3526_DN | |
| Drug | PX-866 | 3.06e-05 | 20 | 70 | 3 | CID009849735 | |
| Disease | Seizures | 6.51e-07 | 218 | 67 | 7 | C0036572 | |
| Disease | developmental and epileptic encephalopathy 64 (implicated_via_orthology) | 5.08e-06 | 2 | 67 | 2 | DOID:0070375 (implicated_via_orthology) | |
| Disease | MEGALENCEPHALY-POLYMICROGYRIA-POLYDACTYLY-HYDROCEPHALUS SYNDROME 1 | 1.52e-05 | 3 | 67 | 2 | C4012727 | |
| Disease | Megalanecephaly Polymicrogyria-Polydactyly Hydrocephalus Syndrome | 3.04e-05 | 4 | 67 | 2 | C1863924 | |
| Disease | renal cell carcinoma | 1.21e-04 | 42 | 67 | 3 | EFO_0000681 | |
| Disease | cancer (implicated_via_orthology) | 3.63e-04 | 268 | 67 | 5 | DOID:162 (implicated_via_orthology) | |
| Disease | histidine measurement | 4.62e-04 | 66 | 67 | 3 | EFO_0009769 | |
| Disease | non-small cell lung carcinoma | 6.72e-04 | 75 | 67 | 3 | EFO_0003060 | |
| Disease | pulmonary non-tuberculous mycobacterial infection | 8.47e-04 | 19 | 67 | 2 | MONDO_0018469 | |
| Disease | Liver carcinoma | 1.03e-03 | 507 | 67 | 6 | C2239176 | |
| Disease | triacylglycerol 58:9 measurement | 1.14e-03 | 22 | 67 | 2 | EFO_0010443 | |
| Disease | migraine disorder | 1.32e-03 | 357 | 67 | 5 | MONDO_0005277 | |
| Disease | glioblastoma (is_implicated_in) | 1.36e-03 | 24 | 67 | 2 | DOID:3068 (is_implicated_in) | |
| Disease | lung squamous cell carcinoma (is_implicated_in) | 1.36e-03 | 24 | 67 | 2 | DOID:3907 (is_implicated_in) | |
| Disease | Adenocarcinoma of large intestine | 1.37e-03 | 96 | 67 | 3 | C1319315 | |
| Disease | obesity (implicated_via_orthology) | 1.47e-03 | 215 | 67 | 4 | DOID:9970 (implicated_via_orthology) | |
| Disease | platelet component distribution width | 1.60e-03 | 755 | 67 | 7 | EFO_0007984 | |
| Disease | Malignant neoplasm of pancreas | 1.64e-03 | 102 | 67 | 3 | C0346647 | |
| Disease | lung small cell carcinoma (is_implicated_in) | 1.85e-03 | 28 | 67 | 2 | DOID:5409 (is_implicated_in) | |
| Disease | hepatocellular carcinoma (biomarker_via_orthology) | 1.93e-03 | 108 | 67 | 3 | DOID:684 (biomarker_via_orthology) | |
| Disease | MITOCHONDRIAL COMPLEX I DEFICIENCY | 2.12e-03 | 30 | 67 | 2 | C1838979 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| SDFPDEEWLWDYEKH | 371 | Q8N1M1 | |
| DYWPREIHFRDDDKW | 36 | Q96M60 | |
| EWERYIQWVEENFPE | 26 | O43683 | |
| NYKDVDWNDRTPLHW | 36 | B4E2M5 | |
| LEWTDYRLSWDPAEH | 81 | P11230 | |
| RVVLHWDLYVWDEEQ | 291 | A1A5B4 | |
| LQDYWDPDHSSDVWV | 41 | A0A1B0GTC6 | |
| EVLEDNDYGRAVDWW | 316 | Q9Y243 | |
| EATADVEWRWHPYTN | 266 | Q96G21 | |
| EEVWLYWIDSNKEPH | 691 | Q14571 | |
| VEWDYSPQREWEKEL | 741 | P00450 | |
| WPEWHHDDDNTIYES | 331 | Q5TGI0 | |
| WDTYRHDIDCQWVDI | 671 | Q96JB6 | |
| PHHSDYDEEEWDRVW | 511 | O15327 | |
| AHLDETVWERPHEFW | 391 | P08686 | |
| DHYVDFQELGWRDWI | 251 | P58166 | |
| PYSQWPRAEDVDLEW | 1596 | Q9Y4D7 | |
| YGEQRAWDLALHTWE | 61 | Q9C000 | |
| YEREDPVIQWFWEVV | 806 | Q8IYU2 | |
| QFWETYEELSPWIEE | 1911 | O94854 | |
| RSQHERDPWYSWDQP | 81 | O95169 | |
| AEWYWGDISREEVNE | 331 | P27986 | |
| QDAEWYWGDISREEV | 326 | O00459 | |
| QDAEWYWGDISREEV | 61 | Q92569 | |
| QEWIDVKLRWNPDDY | 101 | P30532 | |
| WCPELEELHYQAAWR | 2091 | Q13315 | |
| REYWDYESHVVEWGN | 21 | Q8NEV1 | |
| REGDNVNYDWIHWDP | 166 | Q04446 | |
| AERFLYRWWPHLDDV | 201 | Q9BXS1 | |
| GEYRHWNEWDASQPQ | 176 | P26998 | |
| WYDEEESLYPAVWLR | 21 | O75936 | |
| ITWPDEHYSEFQADW | 76 | O75936 | |
| HELYVSFRDLGWQDW | 356 | P22003 | |
| REYWDYESHVVEWGN | 21 | P68400 | |
| EVEWDYAPNKNWEFE | 741 | Q6MZM0 | |
| WDVSRNQPYIDDEWS | 366 | Q86UE4 | |
| EHLNWDPEEVAEWIS | 541 | Q9P1V8 | |
| NFWQNDWERFHADPD | 176 | Q12770 | |
| PDWQWDQEHEEAFLA | 1126 | Q9P2P1 | |
| QLHDFWRLDYWEDDL | 2061 | Q8NFP9 | |
| EVEWDYCPDRSWERE | 741 | Q9BQS7 | |
| ENQEYFEKHRWPPVW | 656 | Q9BYZ6 | |
| EIQAYDPEHWVWARD | 246 | P0DUX0 | |
| EIQAYDPEHWVWARD | 246 | P0DTA3 | |
| EIQAYDPEHWVWARD | 246 | P0DUD1 | |
| DNQEYFERHRWPPVW | 641 | O94844 | |
| LHDVAYEEATPWRWQ | 601 | Q68BL8 | |
| YEEATPWRWQGHSDV | 606 | Q68BL8 | |
| LEEIQAYDPEHWVWA | 381 | A6NHP3 | |
| AYDPEHWVWARDRAH | 386 | A6NHP3 | |
| YHWDVPEDWEGFQHT | 146 | Q8N4L4 | |
| VEIPYHEILWREWED | 211 | Q9UNK9 | |
| HEILWREWEDFSTQP | 216 | Q9UNK9 | |
| EWAHLRWGVFDEYNE | 156 | Q14CN2 | |
| WIDIQLRWGDYDSHD | 1661 | Q6P2Q9 | |
| DVAWEYKWELHEALE | 136 | Q6AZZ1 | |
| EIQAYDPEHWVWARD | 246 | P0DUX1 | |
| EIQAYDPEHWVWARD | 246 | A0A494C0Z2 | |
| EIQAYDPEHWVWARD | 246 | P0DUD3 | |
| EIQAYDPEHWVWARD | 246 | P0DUD4 | |
| LEEIQAYDPEHWVWA | 291 | A6NNV3 | |
| AYDPEHWVWARDRAR | 296 | A6NNV3 | |
| EIQAYDPEHWVWARD | 246 | P0DUD2 | |
| LEEIQAYDPEHWVWA | 331 | P0DV79 | |
| AYDPEHWVWARDRAR | 336 | P0DV79 | |
| LEEIQAYDPEHWVWA | 381 | A0A494C086 | |
| AYDPEHWVWARDRAH | 386 | A0A494C086 | |
| LEEIQAYDPEHWVWA | 381 | Q495Y8 | |
| AYDPEHWVWARDRAH | 386 | Q495Y8 | |
| IQAYDPEHWVWARDR | 531 | A6NKU9 | |
| MEEIQAYDPEHWVWA | 216 | A6NLX3 | |
| AYDPEHWVWARDRTL | 221 | A6NLX3 | |
| LEEIQAYDPEHWVWA | 381 | A6NIY4 | |
| AYDPEHWVWARDRAH | 386 | A6NIY4 | |
| LEEIQAYDPEHWVWA | 381 | P0CI01 | |
| AYDPEHWVWARDRAH | 386 | P0CI01 | |
| ELEEIQAYDPEHWVW | 186 | Q495Y7 | |
| QAYDPEHWVWARDRA | 191 | Q495Y7 | |
| EEIQAYDPEHWVWAR | 316 | Q8NFV5 | |
| EAEALRIWEACWAHY | 621 | Q8TBP0 | |
| DYEAGDIPTEWEAWI | 61 | Q8N183 | |
| YHDLEDPQWICAWQT | 176 | Q5T7W7 | |
| PEDRWYEAEKVWLAQ | 506 | Q8IUG5 | |
| EEWQHLDPAQRRLYW | 81 | P51814 | |
| HDWTWLAPLAEEEDD | 911 | Q9UI33 | |
| EIQAYDPEHWVWARD | 271 | A6NJR5 | |
| EIQAYDPEHWVWARD | 246 | A0A494C191 | |
| IHWYWQLEEECANEP | 456 | P35968 | |
| DWPAQQRAWEAEHRD | 411 | Q00G26 | |
| AILEYEQDHDWPKHW | 241 | Q9Y2B5 | |
| FYWWDLNHLDTDEPV | 241 | Q96FK6 | |
| EYQLWEDHWIRCSKE | 2816 | Q9Y4A5 | |
| RPDWEVAAEAWDNHL | 656 | P35125 | |
| NSDWIRVDPWECYQD | 76 | Q9BZQ4 |