Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioniron ion binding

JMJD6 CYP26C1

3.60e-03166112GO:0005506
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

DHX35 JMJD6 DNMT3L

4.56e-03645113GO:0140640
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

JMJD6 CYP26C1

4.88e-03194112GO:0016705
Pubmed

A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors.

MAGI2 MALRD1

1.72e-052011235224516
Pubmed

Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity.

MAGI2 MALRD1

1.72e-052011233888907
Pubmed

Identification of novel markers of mouse fetal ovary development.

MAGI2 PANK1

2.94e-052611222844512
Pubmed

DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components.

DHX35 RPL7

2.23e-047111229773831
CytobandEnsembl 112 genes in cytogenetic band chr10q23

PANK1 CYP26C1

9.63e-04195112chr10q23
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP33 MALRD1

4.76e-0413411264979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP33 PANK1

5.19e-041401127b359bfbd404ab06d799048252f4985d85852048
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP33 MALRD1

5.34e-041421125690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP33 PTPRA

6.19e-04153112489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZMYND15 PTPRA

6.35e-0415511293bfcf5c12cbb61a1e0444312afd2aa411a8bf50
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 DNMT3L

6.44e-04156112dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 DNMT3L

6.44e-04156112abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RPL7 MALRD1

7.19e-04165112dc70e050465d1f05bb4115356dc978aa581149b5
ToppCellfacs-Tongue-nan-3m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 RPL7

7.46e-04168112ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEMP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RPL7 MALRD1

7.54e-041691129a2fedee8ff90513bc2cbe2a65d07575ee8a0b70
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 DNMT3L

7.72e-04171112508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 DNMT3L

7.72e-0417111225493a4a7b636920e2cfd984542cc500709c9dcf
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 DNMT3L

7.90e-0417311263f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZMYND15 MAGI2

8.46e-041791124f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCelldroplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 MAGI2

8.46e-04179112d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RPL7 CYP26C1

8.55e-041801126c0115d03ec58bc7ae5317bf8906617489975351
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAGI2 DNMT3L

8.64e-04181112ebf1ae963a2b22e1772752ed85a4fb0e546d377e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PANK1 MALRD1

8.74e-04182112041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellControl-Lymphoid-T_Cytotoxic|Lymphoid / Disease state, Lineage and Cell class

RPL7 JMJD6

9.62e-04191112ff7204f9b645233548cf804cf6fe0c86417be87f
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RPL7 MAGI2

9.92e-0419411285e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTPRA MALRD1

9.92e-0419411268d15917ae222cba0ad9e716d29eebb6c5f00f69
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RPL7 MAGI2

1.01e-0319611222538376a95fe3afe8639a216a5497087aa94110
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RPL7 JMJD6

1.04e-03199112c142c2e5874b811991905ed46f9c5a67a811e8a0
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPL7 MALRD1

1.04e-03199112f544229f471b4717166dd4b588399afe45cc31b5
ToppCellcontrol-unassigned|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARHGAP33 JMJD6

1.04e-031991125db7c8089172ac8e796613b3cef618d87007a0ab
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPL7 MALRD1

1.05e-03200112fc77a0c53201c60933d188ea8d4d86bac6325422
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPL7 MALRD1

1.05e-03200112742441800a2d167c19cee4816ff77424ae6675c6
Diseaseasthma exacerbation measurement

PANK1 MALRD1

5.31e-0493112EFO_0007614
Diseasecolorectal health

DHX35 MAGI2

2.44e-03201112EFO_0008460
DiseaseSchizophrenia

MAGI2 PTPRA DNMT3L

3.68e-03883113C0036341
Diseasetriglyceride measurement, high density lipoprotein cholesterol measurement

ZMYND15 MALRD1

4.47e-03274112EFO_0004530, EFO_0004612
Diseasemosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement

DHX35 MAGI2

6.34e-03328112EFO_0008377, EFO_0008378
DiseaseC-reactive protein measurement

RPL7 ARHGAP33 CYP26C1

8.78e-031206113EFO_0004458
Diseasesevere acute respiratory syndrome, COVID-19

MAGI2 MALRD1

1.15e-02447112EFO_0000694, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
RPKPGSPRPFFWMFV

DNMT3L

271

Q9UJW3
PYRWFVMGPPRSGTG

JMJD6

171

Q6NYC1
RGGFFSPWKTPKPIM

MAGI2

681

Q86UL8
NFLWPFKLSSPRGGM

RPL7

206

P18124
SWTKRSGMIGLSPPF

MALRD1

91

Q5VYJ5
PYSGPTRSWSPFRSM

ARHGAP33

1096

O14559
MAAPVGPVKFWRPGT

DHX35

1

Q9H5Z1
TLPLPKGSMGWPFFG

CYP26C1

46

Q6V0L0
TSWPDFGVPFTPIGM

PTPRA

406

P18433
MDSGRKNRPPFPWFG

PANK1

226

Q8TE04
KTPMRTWGPRPGFTF

ZMYND15

291

Q9H091