Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Akirin	AKIRIN1 AKIRIN2	2.30e-05	2	90	2	IPR024132
Domain	RhoGEF	OBSCN PLEKHG5 FGD3 FARP2	3.24e-04	68	90	4	SM00325
Domain	RhoGEF	OBSCN PLEKHG5 FGD3 FARP2	3.63e-04	70	90	4	PF00621
Domain	DH_2	OBSCN PLEKHG5 FGD3 FARP2	3.63e-04	70	90	4	PS50010
Domain	DH-domain	OBSCN PLEKHG5 FGD3 FARP2	3.83e-04	71	90	4	IPR000219
Domain	-	OBSCN PLEKHG5 FGD3 FARP2	3.83e-04	71	90	4	1.20.900.10
Domain	Cyclin_N	CCNE1 CCNI2 CCNP	5.32e-04	33	90	3	IPR006671
Domain	Cyclin_N	CCNE1 CCNI2 CCNP	5.32e-04	33	90	3	PF00134
Domain	CYCLIN	CCNE1 CCNI2 CCNP	8.08e-04	38	90	3	SM00385
Domain	-	CCNE1 CCNI2 CCNP	9.40e-04	40	90	3	1.10.472.10
Domain	Cyclin-like	CCNE1 CCNI2 CCNP	1.16e-03	43	90	3	IPR013763
Domain	PH	PSD OBSCN PLEKHB1 PLEKHG5 FGD3 FARP2	2.26e-03	278	90	6	SM00233
Domain	PH_DOMAIN	PSD OBSCN PLEKHB1 PLEKHG5 FGD3 FARP2	2.30e-03	279	90	6	PS50003
Domain	FH2	GRID2IP FHDC1	2.31e-03	15	90	2	PS51444
Domain	FH2_Formin	GRID2IP FHDC1	2.31e-03	15	90	2	IPR015425
Domain	FH2	GRID2IP FHDC1	2.31e-03	15	90	2	PF02181
Domain	FH2	GRID2IP FHDC1	2.31e-03	15	90	2	SM00498
Domain	PH_domain	PSD OBSCN PLEKHB1 PLEKHG5 FGD3 FARP2	2.34e-03	280	90	6	IPR001849
Domain	-	PSD APBA1 OBSCN PLEKHB1 PLEKHG5 FGD3 FARP2	2.81e-03	391	90	7	2.30.29.30
Domain	DH_1	OBSCN PLEKHG5 FARP2	3.49e-03	63	90	3	PS00741
Domain	PH_dom-like	PSD APBA1 OBSCN PLEKHB1 PLEKHG5 FGD3 FARP2	4.50e-03	426	90	7	IPR011993
Domain	PH	PSD OBSCN PLEKHB1 FGD3 FARP2	5.01e-03	229	90	5	PF00169
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CCNE1 RABL6 SEMA4B ABCA2 AATK KMT2B MTHFD1L BTBD7 RPTOR NEK8 GTSE1 OBSCN PRKDC GRIN2D SRCAP TESK1 PLEKHG5 RNF43 KIFC2 C2CD2L	1.66e-11	1105	95	20	35748872
Pubmed	Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice.	AKIRIN1 AKIRIN2	7.38e-06	2	95	2	18066067
Pubmed	Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.	NFATC2 GSK3B	7.38e-06	2	95	2	37553428
Pubmed	Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E.	CCNE1 GSK3B	7.38e-06	2	95	2	8861947
Pubmed	Evolution of the multifaceted eukaryotic akirin gene family.	AKIRIN1 AKIRIN2	7.38e-06	2	95	2	19200367
Pubmed	NFAT1 transcription factor regulates cell cycle progression and cyclin E expression in B lymphocytes.	CCNE1 NFATC2	7.38e-06	2	95	2	27399331
Pubmed	GSK-3β Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression.	NFATC2 GSK3B	7.38e-06	2	95	2	26823495
Pubmed	Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.	NFATC2 MTHFD1L RPTOR TIMM50 PRKDC GSK3B	9.84e-06	178	95	6	27637333
Pubmed	TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway.	NFATC2 GSK3B	2.21e-05	3	95	2	34311033
Pubmed	An X11alpha/FSBP complex represses transcription of the GSK3beta gene promoter.	APBA1 GSK3B	2.21e-05	3	95	2	20531236
Pubmed	[Roles of DNA dependent protein kinase in silica-induced cyclin E and CDK2 expressions and cell cycle changes in human embryo lung fibroblasts].	CCNE1 PRKDC	2.21e-05	3	95	2	21941773
Pubmed	Immunodeficient and immunosuppressed mice as models to test anti-Pneumocystis carinii drugs.	PAX4 PRKDC	2.21e-05	3	95	2	9021175
Pubmed	Divergent roles of GSK3 and CDK5 in APP processing.	APBA1 GSK3B	2.21e-05	3	95	2	14651959
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	LRRC3 KMT2B NEK8 GRIN2D KIFC2 GNS RPL13	3.45e-05	329	95	7	17474147
Pubmed	A high-lipid diet potentiates left ventricular dysfunction in nitric oxide synthase 3-deficient mice after chronic pressure overload.	NEK8 NOS3	4.41e-05	4	95	2	20554900
Pubmed	Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation.	CCNE1 GSK3B	4.41e-05	4	95	2	14536078
Pubmed	p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK.	PRKDC GSK3B	4.41e-05	4	95	2	18505846
Pubmed	The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability.	CCNE1 PRKDC	4.41e-05	4	95	2	16223725
Pubmed	The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells.	TONSL PRKDC	7.34e-05	5	95	2	29478807
Pubmed	Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro.	CCNE1 CIZ1	7.34e-05	5	95	2	20215406
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L4 FOXD4L5	7.34e-05	5	95	2	12234674
Pubmed	Eyes absent: a gene family found in several metazoan phyla.	NFATC2 EYA2	7.34e-05	5	95	2	9195991
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L4 FOXD4L5	1.10e-04	6	95	2	27092474
Pubmed	The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.	APC2 GSK3B	1.10e-04	6	95	2	10074433
Pubmed	mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).	RPTOR PRKDC	1.54e-04	7	95	2	24870234
Pubmed	Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.	APC2 GSK3B	1.54e-04	7	95	2	10330403
Pubmed	mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system.	RPTOR GSK3B	1.54e-04	7	95	2	27026523
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	OBSCN PLEKHG5 FGD3	1.55e-04	38	95	3	11756498
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TOX4 OSBPL2 PLEKHG5 FARP2	1.74e-04	101	95	4	9872452
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	CCNE1 TIMM50 PRKDC PROSER2 GSK3B RPL13 FARP2	1.88e-04	432	95	7	23455922
Pubmed	Quantitative nanoproteomics for protein complexes (QNanoPX) related to estrogen transcriptional action.	RPS2 PRKDC RPL13	1.95e-04	41	95	3	19805454
Pubmed	RNF43 ubiquitinates and degrades phosphorylated E-cadherin by c-Src to facilitate epithelial-mesenchymal transition in lung adenocarcinoma.	RNF43 GSK3B	2.05e-04	8	95	2	31286874
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L4 FOXD4L5	2.05e-04	8	95	2	8530406
Pubmed	RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.	CCNE1 GSK3B	2.05e-04	8	95	2	19470470
Pubmed	NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.	OBSCN PLEKHG5 FGD3	2.25e-04	43	95	3	12376548
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	POM121 PIM2 MTHFD1L TIMM50 KPRP C1orf167 PROSER2 KIFC2 RPL13	2.25e-04	754	95	9	35906200
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	PSD RPTOR KDM5C BACH2 CIZ1 TIMM50 SRCAP RNF43 UNC80 WDR62 C2CD2L	2.36e-04	1116	95	11	31753913
Pubmed	Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease.	PIM2 TNFRSF13C	2.62e-04	9	95	2	16973390
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L4 FOXD4L5	2.62e-04	9	95	2	12412011
Pubmed	Location of preganglionic neurons is independent of birthdate but is correlated to reelin-producing cells in the spinal cord.	EVX1 NOS3	2.62e-04	9	95	2	15236237
Pubmed	RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.	RNF43 GSK3B	2.62e-04	9	95	2	32965059
Pubmed	DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA.	PRKDC GSK3B	2.62e-04	9	95	2	15678105
Pubmed	Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta.	APC2 GSK3B	2.62e-04	9	95	2	9601641
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2B RPTOR KDM5C GTSE1 PRKDC PROSER2 GSK3B WDR62 SMTN	2.73e-04	774	95	9	15302935
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	HTR1E RGS9 GRIN2D GSK3B	3.16e-04	118	95	4	19156168
Pubmed	Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening.	PRKDC GSK3B	3.28e-04	10	95	2	25495526
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	RPTOR PRKDC	4.00e-04	11	95	2	20427287
Pubmed	Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex.	NFATC2 GSK3B	4.00e-04	11	95	2	21709260
Pubmed	Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks.	NEK8 PLEKHB1 NOS3 GSK3B	4.05e-04	126	95	4	24319055
Pubmed	Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.	RPTOR GSK3B	4.79e-04	12	95	2	18851840
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	MTHFD1L RPTOR TONSL TIMM50 GTPBP3 WDR62 PPIF	5.39e-04	515	95	7	31617661
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	RABL6 HROB RPS2 TRIM26 BTBD7 RPTOR GTSE1 PROSER2 GSK3B FARP2	5.48e-04	1038	95	10	26673895
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L4 FOXD4L5	5.65e-04	13	95	2	16884697
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L4 FOXD4L5	5.65e-04	13	95	2	7957066
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KMT2B KDM5C	5.65e-04	13	95	2	24619213
Pubmed	Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).	OBSCN PLEKHG5 FGD3	6.04e-04	60	95	3	12787561
Pubmed	CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.	KPRP MRPL19 PPIF	7.29e-04	64	95	3	36369321
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXD4L4 TOX4 NFATC2 TRIM26 BACH2 PAX4 RNF43 FOXD4L5	7.34e-04	709	95	8	22988430
Pubmed	Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.	RPTOR GSK3B	7.57e-04	15	95	2	19850877
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L4 FOXD4L5	7.57e-04	15	95	2	7689224
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L4 FOXD4L5	7.57e-04	15	95	2	22045912
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	FOXD4L4 FOXD4L5	8.64e-04	16	95	2	8861101
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L4 FOXD4L5	8.64e-04	16	95	2	10208738
Pubmed	Glycogen synthase kinase 3 β-dependent Snail degradation directs hepatocyte proliferation in normal liver regeneration.	CCNE1 GSK3B	8.64e-04	16	95	2	21690373
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	ABCA2 RPS2 MTHFD1L TRIM26 BTBD7 TIMM50 MRPL19 C1orf167 PRKDC GSK3B RPL13	1.05e-03	1335	95	11	29229926
Pubmed	Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.	PLEKHG5 FARP2	1.10e-03	18	95	2	12799088
Pubmed	USP25 deficiency promotes T cell dysfunction and transplant acceptance via mitochondrial dynamics.	RPS2 RPL13	1.10e-03	18	95	2	36822087
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TRIM26 RPTOR KDM5C BACH2 TONSL SRCAP GSK3B	1.17e-03	588	95	7	38580884
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	AATK POM121 AKIRIN1 GTSE1 APC2 TONSL	1.19e-03	430	95	6	35044719
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L4 FOXD4L5	1.22e-03	19	95	2	9895322
Pubmed	Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression.	NFATC2 GSK3B	1.22e-03	19	95	2	20219685
Pubmed	Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.	RPTOR PRKDC	1.22e-03	19	95	2	20801936
Pubmed	EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3.	POM121 RPS2 PRKDC RPL13	1.35e-03	174	95	4	35031058
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L4 FOXD4L5	1.36e-03	20	95	2	12812790
Pubmed	Identification of Protor as a novel Rictor-binding component of mTOR complex-2.	RPTOR RPL13	1.36e-03	20	95	2	17461779
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2B KDM5C	1.50e-03	21	95	2	27626377
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L4 FOXD4L5	1.50e-03	21	95	2	9449667
Pubmed	A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.	NFATC2 EYA2	1.65e-03	22	95	2	24301466
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L4 FOXD4L5	1.65e-03	22	95	2	17389379
Pubmed	KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.	NOS3 GSK3B	1.80e-03	23	95	2	28164238
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	CCNE1 RPS2 ARMC5 TIMM50 PRKDC GRIN2D RPL13	1.87e-03	639	95	7	23443559
Pubmed	Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.	RPS2 RPL13	1.96e-03	24	95	2	24725412
Pubmed	CPEB2-eEF2 interaction impedes HIF-1α RNA translation.	SEMA4B C2CD2L	1.96e-03	24	95	2	22157746
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L4 FOXD4L5	1.96e-03	24	95	2	11820816
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L4 FOXD4L5	1.96e-03	24	95	2	29992973
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	POM121 RPS2 GTSE1 CIZ1 TIMM50 KPRP PRKDC SRCAP RPL13	1.97e-03	1024	95	9	24711643
Pubmed	A multipotent progenitor domain guides pancreatic organogenesis.	TOX4 PAX4 RNF43	2.02e-03	91	95	3	17609113
Pubmed	Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.	CCNE1 KMT2B	2.13e-03	25	95	2	25664857
Pubmed	Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV.	TRIM26 PRKDC	2.13e-03	25	95	2	15385968
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	RPS2 MTHFD1L TIMM50 PRKDC	2.13e-03	197	95	4	31620119
Pubmed	Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome.	KDM5C CFP	2.30e-03	26	95	2	10920247
Pubmed	Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation.	NFATC2 GSK3B	2.30e-03	26	95	2	31138536
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L4 FOXD4L5	2.30e-03	26	95	2	15857913
Pubmed	The dynamic interactome of human Aha1 upon Y223 phosphorylation.	POM121 RPS2 RPL13	2.35e-03	96	95	3	26693507
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SEMA4B TOX4 POM121 FHDC1 UNC80 FARP2	2.36e-03	493	95	6	15368895
Pubmed	Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.	PRKDC RPL13	2.48e-03	27	95	2	36266428
Pubmed	mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation.	RPTOR GSK3B	2.48e-03	27	95	2	27807348
Pubmed	Shwachman-Bodian Diamond syndrome is a multi-functional protein implicated in cellular stress responses.	PRKDC RPL13	2.48e-03	27	95	2	19602484
Pubmed	Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.	MTHFD1L MRPL19 GTPBP3 PPIF	2.54e-03	207	95	4	31056398
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	RPS2 MTHFD1L TRIM26 RPTOR TIMM50 MRPL19 GTPBP3 GSK3B WDR62 PPIF C2CD2L	2.56e-03	1496	95	11	32877691
Interaction	TOP3B interactions	CCNE1 RABL6 SEMA4B ABCA2 AATK KMT2B MTHFD1L BTBD7 RPTOR NEK8 GTSE1 APBA1 OBSCN PRKDC GRIN2D SRCAP TESK1 PLEKHG5 RNF43 KIFC2 C2CD2L	8.18e-07	1470	87	21	int:TOP3B
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD PLEKHB1 PLEKHG5 FGD3 FARP2	4.01e-04	206	55	5	682
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OBSCN FGD3 FARP2	1.06e-03	66	55	3	722
Coexpression	GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_DN	CCNE1 PSD PIM2 CIZ1 RGS9 SRCAP PPIF	8.22e-06	199	95	7	M8289
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	AATK HTR1E PSD NAT16 C1orf167 CFAP65	8.13e-07	149	95	6	649eb3441fa859591ea85f1ed5fcf08af272a32b
ToppCell	BAL-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	CCNE1 CCNI2 GTSE1 TONSL FHDC1 PLEKHB1	1.58e-06	167	95	6	6c5aa9077ae7eb8887269d405972bd5b31596b19
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	LRRC3 KDM5C GTSE1 GNS WDR62 SMTN	3.04e-06	187	95	6	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	T_cells-Central_memory_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	PIM2 RPS2 BACH2 CFP PLEKHB1 RPL13	3.44e-06	191	95	6	25dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCell	distal-3-Hematologic-B_cell\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SEMA4B RPS2 BACH2 C12orf42 TNFRSF13C RPL13	4.11e-06	197	95	6	d426ce59ff3c50051119a2e6b9f9e57c649ad1a9
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	AATK PSD NAT16 C1orf167 CFAP65	1.26e-05	140	95	5	82b150e9e9962460a5cd6bef7ee04f28f5c05d1a
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA4B ABCA2 C12orf42 EYA2 KIFC2	2.32e-05	159	95	5	f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCNE1 GTSE1 TONSL TNFRSF13C WDR62	2.77e-05	165	95	5	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HROB METRN TONSL TNFRSF13C FHDC1	2.85e-05	166	95	5	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|368C / Donor, Lineage, Cell class and subclass (all cells)	CCNE1 PIM2 RPTOR CRACDL KIFC2	3.11e-05	169	95	5	0d96c0b4fd26fbc0bf44ff7bed2936eebcc55b74
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCNI2 PAX4 EYA2 PLEKHB1 CFAP65	3.47e-05	173	95	5	cc2e489b91562a0c6fe863e2f796f4a7d2ca27dd
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTBD7 CRACDL BACH2 TONSL EYA2	3.47e-05	173	95	5	de124fb7ded04664d4184bf12f1f201c0784f07c
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD NFATC2 BACH2 PROSER2 OCSTAMP	3.67e-05	175	95	5	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCNE1 GTSE1 TONSL PRKDC WDR62	4.09e-05	179	95	5	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	THPO RNF225 EVX1 RNF43	4.15e-05	90	95	4	3817a5b0235e632d976ea565175bdbebbd959bf0
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	THPO RNF225 EVX1 RNF43	4.15e-05	90	95	4	a528f5dcee1a356dea89ff2588d2e0f276f2d5fc
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	APBA1 RGS9 C8orf34 KIAA1614 SMTN	4.31e-05	181	95	5	fc51468c74534b60b4e786bd512d0f1c5dc05de7
ToppCell	(2)_B_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	PIM2 BACH2 C12orf42 TNFRSF13C RPL13	4.78e-05	185	95	5	b0cbebe01b3c2e350d7ef2e6d269f2be6f3a152e
ToppCell	343B-Lymphocytic-B_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	4.91e-05	186	95	5	4d339d27e0aa18096554c8325107327b68511fa3
ToppCell	343B-Lymphocytic-B_cell-\|343B / Donor, Lineage, Cell class and subclass (all cells)	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	4.91e-05	186	95	5	f76b904aa4cbbd0405bf75ffce69ddceae1af89a
ToppCell	Bac-SEP-Lymphocyte-B\|Bac-SEP / Disease, Lineage and Cell Type	PIM2 RPS2 BACH2 TNFRSF13C RPL13	5.03e-05	187	95	5	027aa7b5be402fc82ae13c346dfb4c0c751a07e9
ToppCell	356C-Lymphocytic-B_cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	5.29e-05	189	95	5	5168038d098ed59f042059a9f82496ddadf98e8f
ToppCell	356C-Lymphocytic-B_cell-\|356C / Donor, Lineage, Cell class and subclass (all cells)	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	5.29e-05	189	95	5	4aea4c86ba3641e34952bb3954a26655cff314b9
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C12orf42 BCAN PLEKHB1 RNF43 UNC80	5.43e-05	190	95	5	e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCell	ILEUM-inflamed-(2)_Naive_B_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	5.43e-05	190	95	5	a08d10f8145247d16c952a6f83957f5b57c6940b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	5.43e-05	190	95	5	0724665ac8238f2383c3a929d89abf4a48ec2420
ToppCell	severe-B_naive\|severe / disease stage, cell group and cell class	NEK8 BACH2 C12orf42 TNFRSF13C RPL13	5.43e-05	190	95	5	2430a1fd18385305bf1b604747ff64026a8d5edf
ToppCell	18-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	RPS2 RPTOR AKIRIN2 UNC80 SMTN	5.56e-05	191	95	5	86ce98d2c90c196474b06869de888cf5d1eed196
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-B_naive-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	5.84e-05	193	95	5	95ec708d963e9411e2dcf65650ae71a26e9d0e7f
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-B_naive\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	5.84e-05	193	95	5	d0d0835304647758e6ad4348402a4f76a76137a0
ToppCell	mild-Lymphocytic-B_cells_1\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SEMA4B RPS2 BACH2 TNFRSF13C RPL13	5.99e-05	194	95	5	fad1986cba9cd23ac68e639d7335fbcd6ae2a4e7
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Follicular_B_cells\|normal_Pleural_Fluid / Location, Cell class and cell subclass	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	5.99e-05	194	95	5	678da250aa881ff29482bc464affca7a5f360dc5
ToppCell	Healthy_donor-B_naive\|World / disease group, cell group and cell class (v2)	SEMA4B PIM2 BACH2 C12orf42 TNFRSF13C	6.14e-05	195	95	5	c66bbfdf0091cc62aa50edfa88820bbda191b7bb
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIM2 NFATC2 RPS2 BACH2 RPL13	6.14e-05	195	95	5	068210aa57e733cbcb54a0b20616f0cb2a1ff639
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIM2 NFATC2 RPS2 BACH2 RPL13	6.14e-05	195	95	5	b765fa52dcfad9069b74fce342d809d10abede39
ToppCell	Healthy/Control-B_naive\|Healthy/Control / Disease group and Cell class	SEMA4B PIM2 BACH2 C12orf42 TNFRSF13C	6.29e-05	196	95	5	e92d2c814d2dcb049f3e455fe66fd40898b3524d
ToppCell	Healthy_donor-B_naive\|Healthy_donor / disease group, cell group and cell class (v2)	SEMA4B PIM2 BACH2 C12orf42 TNFRSF13C	6.29e-05	196	95	5	cf254b1466357984201595fa32408d659eb741ef
ToppCell	Control-CD4+_T_naive\|Control / Disease condition and Cell class	PIM2 RPS2 BACH2 PLEKHB1 RPL13	6.29e-05	196	95	5	10455dd24d4a4466eeecb22949b83085e8333ad2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIM2 RPS2 BACH2 TNFRSF13C RPL13	6.29e-05	196	95	5	c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD4+_T_naive\|COVID-19_Severe / Disease group, lineage and cell class	PIM2 RPS2 BACH2 PLEKHB1 RPL13	6.44e-05	197	95	5	07f74bdadfd28e1d55b3f4a3bf87d5dd65a2e9c5
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIM2 RPS2 BACH2 PLEKHB1 RPL13	6.44e-05	197	95	5	9f0d91bb7aec4f2442259eca1ddf7905f8d40e9b
ToppCell	distal-Hematologic-B_cell-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	6.44e-05	197	95	5	cc1567c3c539edc152118fb957617f8d445132d9
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIM2 RPS2 BACH2 PLEKHB1 RPL13	6.44e-05	197	95	5	258dfe69b5faeaee709422f873b144ca5e4a6452
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PIM2 RPS2 BACH2 PLEKHB1 RPL13	6.44e-05	197	95	5	bf80e39cd68fd5bb85c8726d4f82648391de74ad
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PIM2 RPS2 BACH2 PLEKHB1 RPL13	6.44e-05	197	95	5	296b27348ca7e9acf746f752cf810e4e5baea76c
ToppCell	COVID-19_Severe-CD4+_T_naive\|COVID-19_Severe / Disease condition and Cell class	PIM2 RPS2 BACH2 PLEKHB1 RPL13	6.44e-05	197	95	5	ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCell	COVID-19_Severe-B_naive\|COVID-19_Severe / disease group, cell group and cell class	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	6.44e-05	197	95	5	b8f18b39435e2229ba3bc07a25eb875d1ec11f6f
ToppCell	Sepsis-Bac-SEP-Lymphocyte-B\|Bac-SEP / Disease, condition lineage and cell class	PIM2 RPS2 BACH2 TNFRSF13C RPL13	6.75e-05	199	95	5	1f4c9f4d227c79628de1f6c3fc05ab10217504a9
ToppCell	Sigmoid-B_cell-Follicular_B_cell\|B_cell / Region, Cell class and subclass	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	6.75e-05	199	95	5	2141ab1d4d0885fbed8f76b3994f49b787cb8dd3
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-B-B_memory\|ICU-NoSEP / Disease, condition lineage and cell class	RPS2 TNFRSF13C EYA2 KIAA1614 RPL13	6.75e-05	199	95	5	acd2b87ab0d7d92515cf46ab65b766d6ade818a6
ToppCell	Sepsis-ICU-SEP-Lymphocyte-B\|ICU-SEP / Disease, condition lineage and cell class	PIM2 RPS2 BACH2 TNFRSF13C RPL13	6.75e-05	199	95	5	5d4800d0a6340a9db4e895375cf55eeae464709e
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-OPC_related\|5w / Sample Type, Dataset, Time_group, and Cell type.	RPS2 TNFRSF13C MRPL19 C1orf167 RPL13	6.92e-05	200	95	5	b19a75d4f23e9685cbb6c6fa873d7726f27bd5f2
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_naive\|COVID-19_Severe / Disease, condition lineage and cell class	PIM2 RPS2 BACH2 PLEKHB1 RPL13	6.92e-05	200	95	5	1fb96090b5205e95ec21378bf4b88eec7257cf7e
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B\|COVID-19_Mild / Disease, condition lineage and cell class	SEMA4B PIM2 BACH2 C12orf42 TNFRSF13C	6.92e-05	200	95	5	11b51dfca161342d92126e0a83d10864348ba3ef
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-OPC_related-Oligodendrocyte/OPC\|5w / Sample Type, Dataset, Time_group, and Cell type.	RPS2 TNFRSF13C MRPL19 C1orf167 RPL13	6.92e-05	200	95	5	b99dc49b735430a5ac51159575b904020d861927
ToppCell	(23)_Follicular_B_cell\|World / shred on Cell_type and subtype	RPS2 BACH2 C12orf42 TNFRSF13C RPL13	7.59e-05	204	95	5	b92212322271740ed282b495c33f15455a9d758a
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC3 C12orf42 GPC5 CFAP65	2.11e-04	137	95	4	4dcb15de821439011df1bb0bbd7682d674bd725d
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC3 C12orf42 GPC5 CFAP65	2.11e-04	137	95	4	c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell	IIH-CD4-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	PIM2 RPS2 OBSCN RPL13	2.17e-04	138	95	4	e474a0785a651020156baacbf89c4d2b1e4cc473
ToppCell	COVID-19_Moderate-B_cell\|World / disease group, cell group and cell class	KDM5C BACH2 CCNP TNFRSF13C	2.23e-04	139	95	4	b93e1da87d44e55d75e8cc1b87c2970645679c01
ToppCell	droplet-Heart-nan-3m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF13C PROSER2 FGD3 OCSTAMP	2.30e-04	140	95	4	ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCell	IIF-Lymphocyte-T_NK-dnT\|IIF / Disease, Lineage and Cell Type	TMEM31 MTHFD1L RPTOR KIAA1614	2.69e-04	146	95	4	d0f361662db5f7be26104346e8431f7e30c5ce3a
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-D\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	RPS2 RPL13	2.87e-04	12	95	2	a56a1f6a669d84987e5495fa13ae44a9978c27bc
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCNE1 MTHFD1L PROSER2 GRIN2D	2.91e-04	149	95	4	6e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP2 TONSL EYA2 C8orf34	2.99e-04	150	95	4	47ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAX4 EYA2 PLEKHB1 CFAP65	3.22e-04	153	95	4	20786807bba3bcd70ce744f8b6454e064199ed9f
ToppCell	NS-critical-d_0-4-Lymphoid-NKT\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPS2 TNFRSF13C BCAN RPL13	3.30e-04	154	95	4	08ffa4b6f4a1c3de037acf9d30bd14c195738ad9
ToppCell	facs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4B PIM2 TNFRSF13C PCSK4	3.55e-04	157	95	4	0fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCell	severe_influenza-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	CILP2 PSD CIZ1 OBSCN	3.81e-04	160	95	4	a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-naive_B_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PIM2 RPTOR NEK8 TNFRSF13C	3.81e-04	160	95	4	bfbac5ed3273b4430314c6c25cdc1bf0c42b27a1
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	THPO CRACDL CFAP65 C2CD2L	3.90e-04	161	95	4	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	severe_influenza-CD8+_T_naive\|severe_influenza / disease group, cell group and cell class (v2)	CILP2 PSD CIZ1 OBSCN	3.90e-04	161	95	4	82196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCell	cellseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-ILC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C12orf42 GTPBP3 LINC02694 FGD3	4.00e-04	162	95	4	553f91eaba72bcffb733ede45418bbee39c653ab
ToppCell	Adult-Immune-B_cell-D231\|Adult / Lineage, Cell type, age group and donor	PIM2 BACH2 C12orf42 TNFRSF13C	4.09e-04	163	95	4	4f5821299b265663c7d0352b28285f56e1988841
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRID2IP PAX4 EYA2 CFAP65	4.28e-04	165	95	4	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HROB NAT16 GTSE1 WDR62	4.48e-04	167	95	4	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	mild-Lymphocytic-B_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SEMA4B BACH2 TNFRSF13C BCAN	4.48e-04	167	95	4	0811f7559c2a7151693771e52e14af3978997118
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCNI2 LINC02694 PCSK4 FGD3	4.48e-04	167	95	4	484de3ca4a905067c18d06995601479eef8fc15e
ToppCell	Transverse-Macrophage-Macrophage\|Macrophage / Region, Cell class and subclass	RPS2 RPL13	4.55e-04	15	95	2	dc01050ea1a4450746bc2d42a38cad0375554b40
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	TONSL OBSCN PLEKHB1 C2CD2L	4.58e-04	168	95	4	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	367C-Lymphocytic-B_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	PIM2 C12orf42 TNFRSF13C RPL13	4.58e-04	168	95	4	1943ae24ff90218b8c2c10b4102b5007ae35fc85
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNE1 TONSL PCSK4 ZDHHC1	4.58e-04	168	95	4	b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell	367C-Lymphocytic-B_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	PIM2 C12orf42 TNFRSF13C RPL13	4.58e-04	168	95	4	f4414d462d35abd00e3c1446302d7060f8a48d48
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B MTHFD1L AKIRIN2 PROSER2	4.58e-04	168	95	4	ca65321259711321c175ede67bd67a47aad81d7a
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIM2 MTHFD1L CRACDL EYA2	4.69e-04	169	95	4	573f85075d83a4baba41c3e24dc4d9831823a5e5
ToppCell	NS-critical-d_0-4-Myeloid-Monocyte-derived_DC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPS2 GTSE1 APBA1 GTPBP3	4.69e-04	169	95	4	6fe82db874eff0f86e5c0d1cc81322eb9d7874eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCNE1 HROB GTSE1 WDR62	4.69e-04	169	95	4	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIM2 MTHFD1L CRACDL EYA2	4.69e-04	169	95	4	a24d12199b1a6d9cb243b3a68f4109d3a30b2dcb
ToppCell	Control-T/NK_proliferative\|World / Disease group and Cell class	GTSE1 SCNN1D CFP SMTN	4.69e-04	169	95	4	fca735cbb55fce4d32dc6632a39acea1d16b87ab
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIM2 GRIN2D PCSK4 C8orf34	4.69e-04	169	95	4	1de3ae36d3b60e961bfd9f7bdc37867b82a0417f
ToppCell	Children_(3_yrs)-Immune-B_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BACH2 CCNP C12orf42 TNFRSF13C	4.79e-04	170	95	4	e421f9eedf74baffda1d03707a710ece4b777f29
ToppCell	Int-URO-Lymphocyte-T_NK-CD4_Naive\|Int-URO / Disease, Lineage and Cell Type	PIM2 RPS2 PLEKHB1 RPL13	4.79e-04	170	95	4	577915dd1f5c418b9b98a7a7153e2b5d1b93ca84
ToppCell	LAM-Lymphoid-B-cell-1\|LAM / Condition, Lineage and Cell class	RPS2 BACH2 TNFRSF13C RPL13	4.79e-04	170	95	4	2b822a95a8d7ee193d40231418d6bd4cf9662842
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AATK CIDEC GTSE1 GNS	4.90e-04	171	95	4	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVX1 PAX4 EYA2 CFAP65	4.90e-04	171	95	4	c54dcad75fc378da1943009d7dd872b39ea337c0
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CIDEC BACH2 SCNN1D SMTN	4.90e-04	171	95	4	e59afa0a773dca3b9c208d17510ea55703b42598
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NEK8 ARMC5 TNFRSF13C KIFC2	4.90e-04	171	95	4	5636ec11ed1f7aacf98cd9e85853ee1a05bd2cf2
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCNE1 BACH2 LINC00114 FGD3	4.90e-04	171	95	4	a350a5f840e0fb0ccd29bb29cacc23a89abd8404
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells-Pro-B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCNE1 BACH2 LINC00114 FGD3	4.90e-04	171	95	4	e0a99ca8d4c86b58f54af7755ffd8e0ffbfae5e1
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	BACH2 C12orf42 TNFRSF13C FARP2	4.90e-04	171	95	4	c3e3ea09c73050372314a89b282e36ba5f339d73
Disease	high grade glioma (is_marker_for)	BCAN NOS3 RNF43	2.89e-04	42	90	3	DOID:3070 (is_marker_for)
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	AKIRIN1 AKIRIN2	3.27e-04	9	90	2	DOID:0050340 (implicated_via_orthology)
Disease	Diabetes Mellitus, Sudden-Onset	BACH2 PAX4 NOS3	3.32e-04	44	90	3	C4554117
Disease	Diabetes Mellitus, Ketosis-Prone	BACH2 PAX4 NOS3	3.32e-04	44	90	3	C3837958
Disease	Diabetes, Autoimmune	BACH2 PAX4 NOS3	3.32e-04	44	90	3	C0205734
Disease	Brittle diabetes	BACH2 PAX4 NOS3	3.32e-04	44	90	3	C0342302
Disease	Diabetes Mellitus, Insulin-Dependent	BACH2 PAX4 NOS3	3.55e-04	45	90	3	C0011854
Disease	Tinnitus	NFATC2 APBA1 GPC5 C8orf34	6.86e-04	130	90	4	HP_0000360
Disease	schizophrenia (biomarker_via_orthology)	KDM5C GSK3B	9.41e-04	15	90	2	DOID:5419 (biomarker_via_orthology)
Disease	Dystonia, Limb	KMT2B CIZ1	1.21e-03	17	90	2	C0751093
Disease	Dystonia, Diurnal	KMT2B CIZ1	1.21e-03	17	90	2	C0393610
Disease	Dystonia, Paroxysmal	KMT2B CIZ1	1.36e-03	18	90	2	C0393588
Disease	comparative body size at age 10, self-reported	AATK BTBD7 RPTOR C12orf42 ZDHHC1 FARP2	1.83e-03	420	90	6	EFO_0009819
Disease	unipolar depression, depressive symptom measurement	C12orf42 LINC02694	2.85e-03	26	90	2	EFO_0003761, EFO_0007006

Protein segments in the cluster

Peptide	Gene	Start	Entry
ARAPRCLSRPTAPKS	nan	41	A8MZ25
TAPKSGACLARRRPP	nan	51	A8MZ25
ALLSPGSPKRRRCAP	AKIRIN1	16	Q9H9L7
PCRLTPTLSSARPRE	LINC00114	66	Q6XXX2
VCPRSPPLETRTRTS	BACH2	506	Q9BYV9
ARSALRRPLPPATCR	C1orf167	131	Q5SNV9
SPKRRRCAPLSAPTS	AKIRIN2	21	Q53H80
GCLSPRAVPPATRER	EVX1	46	P49640
PRRLCTRRSSGAPAP	GTPBP3	16	Q969Y2
RSHRRLSPPPSQCTI	HTR1E	161	P28566
RSSCPGPSPGKRRVV	C8orf34	51	Q49A92
TCKPRIIAPSRGSPL	CCNE1	91	P24864
APLPRSNRSRCPGTR	CCNI2	46	Q6ZMN8
PPSPRALRILSRLTC	ARMC5	561	Q96C12
CRVLPLRALPRAVTP	CCNP	91	Q9H8S5
PPRRLRVPCRASSGG	MTHFD1L	21	Q6UB35
ACPSAPAPRRSIISR	RABL6	346	Q3YEC7
SRFIRRPSTTICPSP	RGS9	511	O75916
RPSTTICPSPIRVAL	RGS9	516	O75916
APQISCVPRRPARAL	BCAN	866	Q96GW7
LPRSSPRQARPTIAC	FHDC1	571	Q9C0D6
CLGRHSPVPRPASRS	NFATC2	231	Q13469
ARPGIACLRPVRPFA	METRN	76	Q9UJH8
GRPVRTPTQSPRCSF	GPC5	346	P78333
RRTAPTAALPPRARC	FOXD4L4	391	Q8WXT5
PPRPSLLLVSTRESC	LRRC3	6	Q9BY71
RATLPCHRLICRPPS	CFAP65	236	Q6ZU64
GIPRPPSRSAVLRTC	KIAA1614	841	Q5VZ46
PTTPDSRPRLRAAAC	PCSK4	686	Q6UW60
RARPRVLTLCTRPFP	NAT16	271	Q8N8M0
EGAPVRPVSPRCSLR	DCAF10	446	Q5QP82
GPPITAPVVCTRKRR	MED15	651	Q96RN5
TSVRCRGIPRGPVRP	NEK8	291	Q86SG6
SRPSCIGAAPLRPVS	HROB	91	Q8N3J3
VPATCSRKRGRPPLT	KMT2B	461	Q9UMN6
SQDGRLPRTIPLPSC	FGD3	641	Q5JSP0
GPNPTRARQRLCTPL	CFP	396	P27918
VSSCRARPRPGVSRP	CRACDL	576	Q6NV74
SPLCVPARRRSSEPR	GTSE1	536	Q9NYZ3
RDPRLPPCTLRQALT	NOS3	846	P29474
GLPCTRLRSPAVLAP	PAX4	136	O43316
CSRPAPVTFPTARLR	OBSCN	7931	Q5VST9
LRPSRRPSPRDCGTL	POM121	206	Q96HA1
RCISSALPRRRPPVS	APC2	1631	O95996
PRRGRPALPAVFLCS	APC2	2026	O95996
VRLARRCPRVPPSLG	GRID2IP	66	A4D2P6
PVGSPSRPLSRRQLC	C2CD2L	371	O14523
SRPLSRRQLCPLTPG	C2CD2L	376	O14523
RPRTPPEAIALCSRL	GSK3B	306	P49841
SAPSLPRLVREPVRC	ABCA2	1626	Q9BZC7
RCPPVTTVLIRRPDL	APBA1	741	Q02410
AACRPSTPALSRRTP	BTBD7	951	Q9P203
LRRGSPRHLPSCSPA	GNS	11	P15586
PSSSVSLLCRPVCRP	KRTAP10-12	191	P60413
STSRCLPPPRRLQLF	KPRP	251	Q5T749
GRTVCTRPPRSPNEV	FARP2	866	O94887
TLCDGNPRRPSPVLR	SCNN1D	296	P51172
RARLSRPQRACPSSP	KIFC2	806	Q96AC6
ASGPIRPIVRCPTVR	RPL13	51	P26373
RHRTPPAFTLGCRLP	ODF3L2	136	Q3SX64
SRSCPRVLPRQPSTA	EYA2	51	O00167
RGRELGRVTAPCTPL	PSD	56	A5PKW4
RRSLARDPLCPSRSP	AATK	596	Q6ZMQ8
LCFRPGPALPSTRAR	PROSER2	366	Q86WR7
ALIRRCLAPKPSSRP	PIM2	261	Q9P1W9
RRTAPTAALPPRARC	FOXD4L5	391	Q5VV16
EVSPVCPRPRVRLGS	SEMA4B	816	Q9NPR2
SPRRAPRPCLSLASK	RNF43	111	Q68DV7
SARCPLLPARRPRAA	OCSTAMP	386	Q9BR26
VPRSVPLRLPAARAC	PPIF	16	P30405
HLVSQCPTGRRGRPR	SPATA31C1	71	P0DKV0
RSTTTPPRCSPARER	SRCAP	2421	Q6ZRS2
TLPPTDCRLRPDIRG	OSBPL2	396	Q9H1P3
TPVRDSPCTPRLRSV	RPTOR	706	Q8N122
SPKAPRARPCRVSTA	CIDEC	36	Q96AQ7
PARVCPRPLALEART	CILP2	86	Q8IUL8
RLIKVCSSAPPRPTR	C12orf42	326	Q96LP6
RRSPLPVFLRPSDRC	LINC02694	131	Q8NAA6
NPSPTTRPVSRRCAI	CIZ1	836	Q9ULV3
AARTLLPPPASIACR	MRPL19	21	P49406
DTQPSRCRLPSRRTP	TMEM31	46	Q5JXX7
PRLRRRTPVQLLSCP	PLEKHG5	856	O94827
ARNGSRLACTPTPRP	ZNF503-AS2	56	A6NEH8
GLCTRLATPPRRAPD	TIMM50	21	Q3ZCQ8
LRETFSCLPRPRTEP	UNC80	1356	Q8N2C7
CRAPTRLAPRRGLPA	RNF225	111	M0QZC1
APAGATVPPRSRRVC	PLEKHB1	131	Q9UF11
GPARPSQKRPRCSAT	TONSL	751	Q96HA7
VQPGTPARRCRSLPS	TESK1	426	Q15569
TDVRPISGSRPVCPL	TRIM26	41	Q12899
RRLPRGFPPSASLCL	PRKDC	1151	P78527
PAPPICLRRRTRLST	WDR62	36	O43379
VPSSPRVIRGVGRCS	nan	126	Q8NA96
GRCGSVLVRLIPAPR	RPS2	186	P15880
RSLRGRDAPAPTPCV	TNFRSF13C	6	Q96RJ3
AGPRPCQRSLSVLSP	SMTN	291	P53814
GSPVALSPQPRCVRS	TOX4	561	O94842
RRRIPRTPALCTPLA	ZDHHC1	421	Q8WTX9
CTPLALPAPTTRRRQ	ZDHHC1	431	Q8WTX9
LAPSGLPSLRCPRST	TTC31	446	Q49AM3
LPSLRCPRSTALRSP	TTC31	451	Q49AM3
CPRSTALRSPGLSPL	TTC31	456	Q49AM3
LCVRRAPPTTAVPSR	THPO	171	P40225
GRCVSVPRLLSSPRP	KDM5C	1211	P41229
SSCPRAAPARRLTGP	GRIN2D	1276	O15399