Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvitamin D3 25-hydroxylase activity

CYP2R1 CYP3A5

1.19e-046572GO:0030343
GeneOntologyMolecularFunctionvitamin D 25-hydroxylase activity

CYP2R1 CYP3A5

1.67e-047572GO:0070643
GeneOntologyMolecularFunctiondinucleotide phosphatase activity

CILP2 NUDT6

2.85e-049572GO:0004551
DomainCyt_P450_E_grp-I

CYP2R1 CYP3A5

6.97e-0345522IPR002401
DomainCyt_P450_CS

CYP2R1 CYP3A5

9.57e-0353522IPR017972
Domainfn3

COL14A1 HCFC2 DSCAML1

1.04e-02162523PF00041
PathwayREACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 C1S

9.38e-0771365M1078
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 C1S

1.70e-0680365M6121
PathwayREACTOME_COMPLEMENT_CASCADE

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 C1S

1.02e-05115365M19752
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.69e-0561364M27581
PathwayREACTOME_FCGR_ACTIVATION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

2.75e-0569364M27108
PathwayREACTOME_SCAVENGING_OF_HEME_FROM_PLASMA

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

2.75e-0569364M27150
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

3.08e-0571364M27203
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.44e-0582364M27110
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.55e-0586364M27206
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.55e-0586364M601
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.86e-0587364M27205
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.66e-0595364M29842
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.09e-0498364M27152
PathwayREACTOME_PARASITE_INFECTION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

2.09e-04116364M29843
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

3.63e-04134364M29840
PathwayREACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

3.84e-04136364M27207
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

4.65e-04143364M27107
PathwayREACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.15e-04154364M39007
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

8.14e-04166364M608
PathwayREACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.24e-03186364M27175
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.34e-03190364M8240
PathwayREACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS

CYP3A5 GPX4

1.42e-0322362MM15614
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.45e-03194364M16312
PathwayREACTOME_LEISHMANIA_INFECTION

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

2.26e-03219364M29836
Pubmed

Activation of C1r by proteolytic cleavage.

IGLV2-23 IGLV2-14 IGLV2-11 C1S

8.18e-07435841249422
Pubmed

Physicochemical and functional characterization of the C1r subunit of the first complement component.

IGLV2-23 IGLV2-14 IGLV2-11 C1S

1.18e-0647584814163
Pubmed

One-megabase sequence analysis of the human immunoglobulin lambda gene locus.

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

3.40e-051095849074928
Pubmed

Recognition of immunoglobulins by Fcgamma receptors.

IGLV2-23 IGLV2-14 IGLV2-11

7.22e-054858311955599
Pubmed

Sequence and evolution of the human germline V lambda repertoire.

IGLV2-14 IGLV2-11 IGLV2-8

7.68e-05495838951372
Pubmed

Role of the Drug-Metabolizing Enzyme CYP during Mouse Liver Development.

CYP2R1 CYP3A5

1.49e-041158227904043
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

TNIK MMS22L BBX CYP2R1 CYP3A5 ADAR TRUB2 ARAP2 ALG13

2.02e-04124258930973865
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

MYOF UBTD2 NUDT6 ADAR UST

2.33e-0433258537433992
Pubmed

Characterization of vertebrate cohesin complexes and their regulation in prophase.

STAG2 ANAPC4

2.46e-041458211076961
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

MYOF MMS22L CNDP2 TOP1 STAG2

3.51e-0436358514691545
Pubmed

Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads.

STAG2 ANAPC4

3.66e-041758221043528
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

TNRC6A MAP3K20 ZC3H7B ADAR TOP1 TRUB2 ALG13

3.79e-0480758722681889
Pubmed

¹H NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models.

CLSTN3 AGL

5.09e-042058225849460
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

GNL3L BBX GPX4 TOP1 STAG2 HDGFL3

5.21e-0460858636089195
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNIK CLSTN3 SGSM2 AHCYL2 ARAP2

5.90e-0440758512693553
Pubmed

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.

MYO1D CNDP2

1.08e-032958223396134
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

CMTR1 MYO1D ZC3H7B ADAR TOP1

1.11e-0346958537314180
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

MYO1D TNRC6A ADAR TOP1

1.14e-0327458434244482
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

GNL3L MYO1D TNRC6A GPX4 ZC3H7B ALG13

1.28e-0372358634133714
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MYOF CMTR1 MYO1D TNRC6A ADAR TOP1

1.29e-0372458636232890
Pubmed

The functional interactome landscape of the human histone deacetylase family.

BBX ADAR TOP1 STAG2

1.39e-0328958423752268
Cytoband3q13.1

BBX ALCAM

1.56e-0555823q13.1
Cytoband22q11.2

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.69e-0512058422q11.2
GeneFamilyImmunoglobulin lambda locus at 22q11.2

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

3.96e-0589394353
CoexpressionGSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN

MYOF CNDP2 C1S ADAR TOP1 ARAP2

4.33e-06200566M3405
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

2.52e-061665852b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCellControl-Lymphoid_P|Control / Disease group, lineage and cell class

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

3.35e-06176585d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCellControl-Lymphoid_P-Plasmablast|Control / Disease group, lineage and cell class

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

3.35e-061765854b4416f342b732d2cc60133838728880326257d8
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

3.45e-061775854c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

3.45e-06177585fc40918825b7e1eb6861df59dfca944778a64b98
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

3.45e-06177585d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

3.64e-06179585837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

3.64e-06179585494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell10x5'-Lung-Lymphocytic_B_plasma-Plasmablasts|Lung / Manually curated celltypes from each tissue

KNTC1 IGLV2-14 IGLV2-11 IGLV2-8 ZC3H7B

3.64e-061795853fa75eec3e86fd1797eaa33362257df7f9b2a0bf
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

3.64e-06179585b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TNIK GNL3L NSUN3 TIRAP AGL

4.39e-0618658503db813598b67b1e08f759758a1c2023396921fa
ToppCellhealthy_donor-Lymphocytic-Plasma_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

4.62e-06188585bd53b0371154cff680226897b61c9809a239d1b6
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF C1S COL14A1 ALCAM UST

5.12e-061925850dc1f46e40346ed0b286e53b106a812441575100
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF C1S COL14A1 ALCAM UST

5.66e-061965852029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

5.81e-06197585fdbf4eb9fa5aefb4ffb307494fe4774bf5e0aaeb
ToppCellCOVID_vent-Lymphocytic-Plasma_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

5.95e-06198585e84c5f712e1dea548d0e2aba6625598f9671d3a0
ToppCellControl-Control-Lymphocyte-B-Plasmablast|Control / Disease, condition lineage and cell class

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

6.10e-06199585c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCellCaecum-T_cell-CD8_T|T_cell / Region, Cell class and subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8 ARAP2

6.25e-0620058540e435f5dd1a0f6554f87dc1e170a740fd733d5b
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgG_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGLV2-23 IGLV2-11 IGLV2-8 MYO1D

4.61e-05152584a2ba2d95ac9010e1a62db34dcad10d004f8a90cc
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.10e-051565845d9e1df70f2e9219f6b029be2e39297605d36726
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.36e-0515858417a13c5719eb363f2eb8f1d4e171429c6a1ce1e9
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.36e-05158584e5451cfe67e882eb0c1eca287740f8ab75370abc
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.36e-051585841397078f909338fa5fa3b01748db891e5e3fc9e7
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.49e-051595841827493fb464bbddb2ee23f99472cfbcaf57405b
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.49e-051595846ecc3cb2daa5887b59836842be414a00cdcdaeec
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L CYP2R1 COL14A1 UST

5.49e-051595847ed659163f45e0c4df4782997c0786900c8186c8
ToppCellMild-Lymphoid-Plasma-|Mild / Condition, Lineage, Cell class and cell subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.63e-05160584aa79848913910c01249d6cacf4ed53ec0e4f5c3d
ToppCellMild-Lymphoid-Plasma|Mild / Condition, Lineage, Cell class and cell subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.63e-051605847fdb849f5caf5a127a2582326215e11f8eb4fa0e
ToppCellMild_COVID-19-B_cell-Plasmablast|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

5.91e-05162584b67f6fb3d7f6093c8ef02398ff8fea4d0fb41a3b
ToppCell367C-Lymphocytic-Plasma_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.64e-05167584f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell367C-Lymphocytic-Plasma_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.64e-051675845e768cf24699893e05d1bcb1c92dba2336943a64
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.64e-05167584afb6d0993f3fd44a295874673055189d514f7b11
ToppCell10x5'-Lung-Lymphocytic_B_plasma-Plasma_cells|Lung / Manually curated celltypes from each tissue

IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

6.80e-05168584e8bd090de5c9fe286b08a8b314ce12cf988184f0
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.96e-05169584307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCelltumor_Lung-B_lymphocytes-Plasma_cells|tumor_Lung / Location, Cell class and cell subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

6.96e-05169584b36b7632ce55fc7b6b8b66020563d360b3de6fd7
ToppCell10x5'-Lung-Lymphocytic_B_plasma|Lung / Manually curated celltypes from each tissue

KNTC1 IGLV2-14 IGLV2-11 IGLV2-8

7.45e-051725848156fb6de66a4c92ade703b71c2e9187291e50ef
ToppCellCOPD-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGLV2-23 IGLV2-14 IGLV2-8 MYO1D

7.96e-05175584d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

8.14e-0517658467d6dc38708692f8c58cea5ed896f10718e9ffa6
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

8.14e-05176584125be81311f87563ca321472fcce6e0e0ae24c16
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

8.32e-05177584c2b0fb5921eea24d248d6e6ccb57c29b0832602c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

8.32e-05177584111fb0707ff37ca631d85bb5a09e067ffe568eb8
ToppCellHealthy-Plasmablast|Healthy / disease group, cell group and cell class

IGLV2-14 IGLV2-11 IGLV2-8 MYO1D

8.32e-051775844ff75c609ac9edf7a94bda42eb7124c559e8b6aa
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L CYP2R1 C1S COL14A1

8.51e-05178584c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

8.88e-05180584cea079bc02e08c46600eed05ab9924ec90e1e3d3
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK STAG2 ARAP2 HDGFL3

9.27e-051825841710eab3037a87609d21838be2d2d29c3bc36651
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK STAG2 ARAP2 HDGFL3

9.27e-05182584e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.47e-051835845ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.67e-0518458415f2c10101ccc8ed059520fc082ee42593dff269
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.67e-05184584a90a58d9e319afa1cd572e4c2f516fadc42f56e5
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.87e-0518558496423bdcf0e85ca41370f79347d27c22f3de98f5
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.87e-0518558408bc817908076734d66f2805cb954141f2cc5a18
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.87e-051855840fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.87e-0518558479edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

9.87e-051855841704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGLV2-23 IGLV2-14 IGLV2-11 MYO1D

1.01e-04186584e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

TNIK MAST4 AHCYL2 TOP1

1.03e-04187584030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYOF MYO1D ALCAM ARAP2

1.05e-04188584eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

TNIK MAST4 CYP3A5 DSCAML1

1.07e-041895840be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.09e-0419058479ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCellControl-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

MYOF MAST4 C1S ALCAM

1.09e-041905844e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.09e-0419058418762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF C1S COL14A1 UST

1.09e-0419058445df8fee00f8949937863159d7aa042e72748d9b
ToppCell5'-Adult-LargeIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.12e-04191584d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.12e-041915848c35fccc4617694eae1e55b1107841ffe7f1bac8
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF C1S COL14A1 UST

1.14e-04192584162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF C1S COL14A1 UST

1.14e-041925844e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.14e-041925843dddfc93c3c954c4416c7c1f1f161e4d1dcc1233
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF C1S COL14A1 UST

1.14e-04192584ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF C1S COL14A1 UST

1.14e-04192584f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF C1S COL14A1 UST

1.14e-04192584deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.16e-0419358434f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.19e-04194584f083777353e76a2d9c39f8b6cb1a689b68b81c56
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOF C1S COL14A1 UST

1.19e-0419458489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellControl-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

TNIK MAST4 UST TOP1

1.19e-04194584a01de094f7bfd099bcbb2f94224690a2efb887b4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK MYOF MYO1D PELI2

1.21e-04195584938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.21e-0419558413f4ee21568fd747608412d33559d10561dbb3c8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK MYOF MYO1D PELI2

1.21e-04195584d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell5'-Adult-LargeIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.21e-04195584600174e35574fe7c44dd923adcf43686e7b01e39
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.23e-04196584026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCellBiopsy_IPF-Immune-Plasma_cells|Biopsy_IPF / Sample group, Lineage and Cell type

IGLV2-23 IGLV2-14 IGLV2-11 IGLV2-8

1.23e-04196584a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYOF CLSTN3 C1S COL14A1

1.31e-04199584fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MYOF CLSTN3 C1S COL14A1

1.31e-041995848b86c69aaf60feff53aa782559cfece7342a23de
Diseasevisceral adipose tissue measurement

KNTC1 MMS22L NSUN3 TNRC6A COL14A1 ALCAM ANAPC4

2.36e-05481537EFO_0004765
Diseasehousehold income

MMS22L MAST4 SGSM2 TNRC6A MAP3K20

2.15e-04304535EFO_0009695
Diseasecyclic adenosine monophosphate measurement

MAST4 ARAP2

4.23e-0417532EFO_0010473
Diseaseneurotic disorder

MMS22L BBX ZC3H7B

8.05e-04101533EFO_0004257
Diseaselifestyle measurement

MMS22L NSUN3 SGSM2 ANAPC4

8.46e-04235534EFO_0010724
Diseasemood instability measurement

MMS22L BBX TNRC6A

1.59e-03128533EFO_0008475
Diseasehippocampal volume

TNIK MAST4 DSCAML1 ARAP2

2.00e-03297534EFO_0005035
Diseasedentate gyrus volume measurement

TNIK MAST4

2.25e-0339532EFO_0010083
Diseaseunipolar depression, age at onset

NSUN3 ALCAM

2.36e-0340532EFO_0003761, EFO_0004847
Diseasehippocampal CA4 volume

TNIK MAST4

2.48e-0341532EFO_0009396
Diseasebrain measurement, neuroimaging measurement

TNIK MAST4 TNRC6A ALCAM DSCAML1

3.04e-03550535EFO_0004346, EFO_0004464
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

NSUN3 SGSM2 TNRC6A MAP3K20 ALCAM ARAP2

3.05e-03801536EFO_0003888, EFO_0007052, MONDO_0002491
Diseasevitamin D measurement

CILP2 CYP2R1 RMDN2 ADAR

3.12e-03336534EFO_0004631
Diseaserisky sexual behaviour measurement

MMS22L NSUN3 SGSM2

3.50e-03169533EFO_0007877

Protein segments in the cluster

PeptideGeneStartEntry
PLTPTLYKMHKGWKN

ALG13

196

Q9NP73
LKGMASWKQKYEPLG

ANAPC4

366

Q9UJX5
LSFWMKHGVTPNKGK

CLSTN3

376

Q9BQT9
MKANPGYKWCPTTNK

BBX

141

Q8WY36
PFHMKKSSGDWKVQG

CTSL3P

136

Q5NE16
KKYGKMWGTYEGQLP

CYP3A5

66

P20815
SKGHLPSGMWRQPKD

ARHGEF33

211

A8MVX0
YRGVKKKMKPPTSWG

ARAP2

1491

Q8WZ64
PKWPSHYLMVPGGKH

PADI4

231

Q9UM07
AQHVKMGYGAWYLKP

FAM47C

931

Q5HY64
IPDKGKAWGPMYVAK

NSUN3

316

Q9H649
KMYIFGGWVPHKGEN

HCFC2

256

Q9Y5Z7
MKSNGPHPWKQVKGR

MMS22L

496

Q6ZRQ5
WYQQHPGKAPKLMIY

IGLV2-23

56

P01705
KLKNMWKFPGGLSEP

NUDT6

166

P53370
SPKEGMIKGLWKNHS

KNTC1

1941

P50748
FAKMKGYPHWPARID

HDGFL3

16

Q9Y3E1
PGQDKMKSLWPHKAL

PANX3

96

Q96QZ0
KGLKDMGYGNWISKP

ADAR

1201

P55265
MWAAKSYPSLKPLGG

DNAH3

3926

Q8TD57
YPPPKVMWKHAKGSG

DSCAML1

716

Q8TD84
PNGKPSWDDKCKMPY

CYP2R1

346

Q6VVX0
EGLHKLMWIPVYGGK

COL14A1

651

Q05707
KGWKLRYHGDPMPCP

C1S

281

P09871
LKPGTGPQDCKWKMY

MAP3K20

446

Q9NYL2
AMEKAWAPGGKTNHK

MAST4

2031

O15021
HPLWKWMKIQPKGKG

GPX4

141

P36969
LMFGKWKYEKPDGSP

ALCAM

51

Q13740
KKWHAKGFGMTLKGP

CMTR1

291

Q8N1G2
WYQQHPGKAPKLMIY

IGLV2-11

56

P01706
WYQQHPGKAPKLMIY

IGLV2-14

56

P01704
GTHKGSLKPHDYPKW

PHYH

211

O14832
GGDLTHWIYKKYPNM

AHCYL2

311

Q96HN2
WYQQHPGKAPKLMIY

IGLV2-8

56

P01709
KAAKWKNPDGHMDGL

PELI2

171

Q9HAT8
PGEGSKGHKKISWPY

GNL3L

11

Q9NVN8
WPFLLGHYKFGMSKK

SGSM2

576

O43147
WYHKVRKPGIAMKLP

RMDN2

26

Q96LZ7
GYLKSWPPTKMGLDE

ARNTL

286

O00327
SGTPMPKKYSWFHNG

CILP2

316

Q8IUL8
PNEFKVYMGHGGKPW

CNDP2

371

Q96KP4
RGDGYLHPVKKWPMR

TCF24

121

Q7RTU0
MKKKQQHPGGGADPW

UST

1

Q9Y2C2
YKEGMSPSEKPAWAK

TNIK

521

Q9UKE5
SGDYPLTMAGPQWKK

STAG2

156

Q8N3U4
LMWKENGKKPGSFPK

SPATA31D1

426

Q6ZQQ2
KPKWKSDYPMTDGQL

UBTD2

36

Q8WUN7
GMWKKLQEKFAPKGP

UQCC2

106

Q9BRT2
GSRPKKPLGKMADWF

TIRAP

11

P58753
NMAFGKPAKYWKLDP

TMEM222

96

Q9H0R3
GLFAVYKPPGLKWKH

TRUB2

11

O95900
YPEGIKWKFLEHKGP

TOP1

211

P11387
WPPYTKKMSSKGLSG

TNRC6A

1166

Q8NDV7
KIPGGHWRQMIYAPK

ZNF891

166

A8MT65
EWYLPKMAKHLPGVN

TMEM260

471

Q9NX78
TYDMWLKKHNPGKPG

ZC3H7B

801

Q9UGR2
GNKPEDCPYLWAHMK

AGL

496

P35573
KTMRDYGKHVKWPSP

MYO1D

751

O94832
PDHKPKSWVAAEKMY

MYOF

1001

Q9NZM1