Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionWnt receptor activity

FZD1 TSPAN12 FZD7 FZD2 FZD3

1.52e-1117265GO:0042813
GeneOntologyMolecularFunctionWnt-protein binding

FZD1 FZD7 FZD2 FZD3

1.02e-0734264GO:0017147
GeneOntologyMolecularFunctionPDZ domain binding

FZD1 FZD7 FZD2 FZD3

1.85e-05123264GO:0030165
GeneOntologyMolecularFunctionprotein-cysteine S-stearoyltransferase activity

ZDHHC20 ZDHHC6

3.41e-057262GO:0140439
GeneOntologyMolecularFunctionG protein-coupled receptor binding

FZD1 FZD7 FLNA REEP1 REEP2

6.53e-05337265GO:0001664
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SLC24A3 GRIN1 PIEZO2 PIEZO1 PKD1L1

7.10e-05343265GO:0005261
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC24A3 GRIN1 PIEZO2 SLC5A10 SLC48A1 ABCA13 PIEZO1 PKD1L1

8.71e-051180268GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC24A3 GRIN1 PIEZO2 SLC5A10 SLC48A1 ABCA13 PIEZO1 PKD1L1

1.61e-041289268GO:0005215
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC24A3 GRIN1 PIEZO2 SLC5A10 PIEZO1 PKD1L1

1.72e-04664266GO:0008324
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

PIEZO2 PIEZO1

2.46e-0418262GO:0008381
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SLC24A3 GRIN1 PIEZO2 PIEZO1 PKD1L1

2.77e-04459265GO:0005216
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC24A3 GRIN1 PIEZO2 SLC5A10 PIEZO1 PKD1L1

4.48e-04793266GO:0015075
GeneOntologyMolecularFunctionchannel activity

SLC24A3 GRIN1 PIEZO2 PIEZO1 PKD1L1

5.13e-04525265GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC24A3 GRIN1 PIEZO2 PIEZO1 PKD1L1

5.18e-04526265GO:0022803
GeneOntologyMolecularFunctionprotein-cysteine S-palmitoyltransferase activity

ZDHHC20 ZDHHC6

5.20e-0426262GO:0019706
GeneOntologyMolecularFunctionprotein-cysteine S-acyltransferase activity

ZDHHC20 ZDHHC6

5.20e-0426262GO:0019707
GeneOntologyMolecularFunctioncalcium channel activity

SLC24A3 GRIN1 PKD1L1

6.14e-04129263GO:0005262
GeneOntologyMolecularFunctionS-acyltransferase activity

ZDHHC20 ZDHHC6

6.93e-0430262GO:0016417
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

SLC24A3 GRIN1 PKD1L1

9.70e-04151263GO:0015085
GeneOntologyMolecularFunctionpalmitoyltransferase activity

ZDHHC20 ZDHHC6

1.06e-0337262GO:0016409
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

FZD1 TSPAN12 OPN1LW FZD7 GRIN1 FZD2 FZD3

1.35e-031353267GO:0004888
GeneOntologyMolecularFunctionfrizzled binding

FZD1 FZD7

1.36e-0342262GO:0005109
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC24A3 GRIN1 SLC5A10 PKD1L1

2.89e-03465264GO:0046873
GeneOntologyMolecularFunctionG protein-coupled receptor activity

FZD1 OPN1LW FZD7 FZD2 FZD3

5.09e-03884265GO:0004930
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC24A3 GRIN1 SLC5A10 PKD1L1

8.31e-03627264GO:0022890
GeneOntologyMolecularFunctiongated channel activity

GRIN1 PIEZO2 PIEZO1

9.07e-03334263GO:0022836
GeneOntologyBiologicalProcessWnt signaling pathway, planar cell polarity pathway

FZD1 FZD7 FZD2 FZD3

6.47e-0755264GO:0060071
GeneOntologyBiologicalProcessnon-canonical Wnt signaling pathway

FZD1 FZD7 FZD2 FZD3

2.52e-0677264GO:0035567
GeneOntologyBiologicalProcessmonoatomic cation transport

UMOD SLC24A3 FLNA GRIN1 PIEZO2 SLC5A10 SLC48A1 PIEZO1 PKD1L1

6.99e-061157269GO:0006812
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC24A3 FLNA GRIN1 PIEZO2 SLC5A10 SLC48A1 PIEZO1 PKD1L1

1.38e-05942268GO:0098655
GeneOntologyBiologicalProcessprotein localization to membrane

UMOD ZDHHC20 FLNA GRIN1 REEP1 REEP2 ZDHHC6

1.97e-05705267GO:0072657
GeneOntologyBiologicalProcessestablishment of planar polarity

FZD1 FZD2 FZD3

2.28e-0544263GO:0001736
GeneOntologyBiologicalProcessmuscular septum morphogenesis

FZD1 FZD2

2.28e-056262GO:0003150
GeneOntologyBiologicalProcessestablishment of tissue polarity

FZD1 FZD2 FZD3

2.44e-0545263GO:0007164
GeneOntologyBiologicalProcessmonoatomic ion transport

UMOD SLC24A3 FLNA GRIN1 PIEZO2 SLC5A10 SLC48A1 PIEZO1 PKD1L1

2.79e-051374269GO:0006811
GeneOntologyBiologicalProcessprotein transport into membrane raft

UMOD REEP2

3.20e-057262GO:0032596
GeneOntologyBiologicalProcessestablishment of protein localization to membrane

UMOD ZDHHC20 REEP1 REEP2 ZDHHC6

4.32e-05319265GO:0090150
GeneOntologyBiologicalProcesslocalization within membrane

UMOD ZDHHC20 FLNA GRIN1 REEP1 REEP2 ZDHHC6

4.36e-05798267GO:0051668
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC24A3 FLNA GRIN1 PIEZO2 SLC5A10 SLC48A1 PIEZO1 PKD1L1

4.64e-051115268GO:0034220
GeneOntologyBiologicalProcessdetection of external stimulus

OPN1LW PIEZO2 PIEZO1 PKD1L1

6.19e-05173264GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

OPN1LW PIEZO2 PIEZO1 PKD1L1

6.47e-05175264GO:0009582
GeneOntologyBiologicalProcessmembranous septum morphogenesis

FZD1 FZD2

6.83e-0510262GO:0003149
GeneOntologyBiologicalProcesshard palate development

FZD1 FZD2

6.83e-0510262GO:0060022
GeneOntologyBiologicalProcessprotein transport within lipid bilayer

UMOD REEP2

8.35e-0511262GO:0032594
GeneOntologyBiologicalProcessmorphogenesis of a polarized epithelium

FZD1 FZD2 FZD3

1.04e-0473263GO:0001738
GeneOntologyBiologicalProcessdetection of mechanical stimulus

PIEZO2 PIEZO1 PKD1L1

1.13e-0475263GO:0050982
GeneOntologyBiologicalProcessprotein localization to membrane raft

UMOD REEP2

1.18e-0413262GO:1903044
GeneOntologyBiologicalProcessregulation of establishment of planar polarity involved in neural tube closure

FZD1 FZD2

1.59e-0415262GO:0090178
GeneOntologyBiologicalProcessmetal ion transport

UMOD SLC24A3 FLNA GRIN1 SLC5A10 SLC48A1 PKD1L1

1.80e-041000267GO:0030001
GeneOntologyBiologicalProcessestablishment of planar polarity involved in neural tube closure

FZD1 FZD2

1.81e-0416262GO:0090177
GeneOntologyBiologicalProcessestablishment of planar polarity of embryonic epithelium

FZD1 FZD2

2.31e-0418262GO:0042249
GeneOntologyBiologicalProcessregulation of establishment of planar polarity

FZD1 FZD2

2.58e-0419262GO:0090175
GeneOntologyBiologicalProcessendoplasmic reticulum organization

UMOD REEP1 REEP2

3.24e-04107263GO:0007029
GeneOntologyBiologicalProcessendoplasmic reticulum tubular network organization

REEP1 REEP2

3.48e-0422262GO:0071786
GeneOntologyBiologicalProcessneural tube closure

FZD1 FZD2 FZD3

3.80e-04113263GO:0001843
GeneOntologyBiologicalProcesstube closure

FZD1 FZD2 FZD3

3.90e-04114263GO:0060606
GeneOntologyBiologicalProcessWnt signaling pathway

FZD1 FZD7 WWOX FZD2 FZD3

4.09e-04516265GO:0016055
GeneOntologyBiologicalProcesspeptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine

ZDHHC20 ZDHHC6

4.15e-0424262GO:0018231
GeneOntologyBiologicalProcesspeptidyl-L-cysteine S-palmitoylation

ZDHHC20 ZDHHC6

4.15e-0424262GO:0018230
GeneOntologyBiologicalProcessprimary neural tube formation

FZD1 FZD2 FZD3

4.53e-04120263GO:0014020
GeneOntologyBiologicalProcesssecondary palate development

FZD1 FZD2

5.26e-0427262GO:0062009
GeneOntologyBiologicalProcessneural tube formation

FZD1 FZD2 FZD3

6.25e-04134263GO:0001841
GeneOntologyBiologicalProcessregulation of neural precursor cell proliferation

FLNA FZD3 TAFA1

6.39e-04135263GO:2000177
GeneOntologyBiologicalProcessprotein palmitoylation

ZDHHC20 ZDHHC6

7.88e-0433262GO:0018345
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC24A3 FLNA GRIN1 SLC5A10 SLC48A1 PKD1L1

8.37e-04922266GO:0098662
GeneOntologyBiologicalProcesscanonical Wnt signaling pathway

FZD1 FZD7 FZD2 FZD3

8.50e-04344264GO:0060070
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

UMOD SLC24A3 FLNA GRIN1

9.97e-04359264GO:0006874
GeneOntologyBiologicalProcessembryonic epithelial tube formation

FZD1 FZD2 FZD3

1.03e-03159263GO:0001838
GeneOntologyBiologicalProcessresponse to abiotic stimulus

OPN1LW UMOD GRIN1 PIEZO2 FZD3 PIEZO1 PKD1L1

1.16e-031361267GO:0009628
GeneOntologyBiologicalProcessepithelial tube formation

FZD1 FZD2 FZD3

1.31e-03173263GO:0072175
GeneOntologyBiologicalProcesscalcium ion homeostasis

UMOD SLC24A3 FLNA GRIN1

1.34e-03389264GO:0055074
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

SLC24A3 FLNA GRIN1 PKD1L1

1.38e-03392264GO:0070588
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC24A3 FLNA GRIN1 SLC5A10 SLC48A1 PKD1L1

1.39e-031017266GO:0098660
GeneOntologyBiologicalProcesstube formation

FZD1 FZD2 FZD3

1.64e-03187263GO:0035148
GeneOntologyBiologicalProcessmorphogenesis of embryonic epithelium

FZD1 FZD2 FZD3

1.71e-03190263GO:0016331
GeneOntologyBiologicalProcesspeptidyl-cysteine modification

ZDHHC20 ZDHHC6

1.80e-0350262GO:0018198
GeneOntologyBiologicalProcessneural tube development

FZD1 FZD2 FZD3

2.04e-03202263GO:0021915
GeneOntologyBiologicalProcessventricular septum morphogenesis

FZD1 FZD2

2.26e-0356262GO:0060412
GeneOntologyBiologicalProcessheart development

FZD1 FZD7 FLNA FZD2 PKD1L1

2.28e-03757265GO:0007507
GeneOntologyBiologicalProcessneural precursor cell proliferation

FLNA FZD3 TAFA1

3.05e-03233263GO:0061351
GeneOntologyBiologicalProcessregulation of neuroblast proliferation

FZD3 TAFA1

3.21e-0367262GO:1902692
GeneOntologyCellularComponentendoplasmic reticulum membrane

FADS2 ZDHHC20 TLR7 GRIN1 REEP1 REEP2 ZDHHC6 PIEZO1

1.20e-041293268GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

FADS2 ZDHHC20 TLR7 GRIN1 REEP1 REEP2 ZDHHC6 PIEZO1

1.24e-041299268GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

FADS2 ZDHHC20 TLR7 GRIN1 REEP1 REEP2 ZDHHC6 PIEZO1

1.44e-041327268GO:0042175
GeneOntologyCellularComponentendolysosome

TLR7 SLC48A1

6.33e-0430262GO:0036019
GeneOntologyCellularComponentendoplasmic reticulum tubular network

REEP1 REEP2

6.77e-0431262GO:0071782
MousePhenoabnormal theca cell layer morphology

FADS2 WWOX

2.58e-055232MP:0009365
MousePhenodecreased social investigation

SLC24A3 GRIN1 WWOX

3.16e-0538233MP:0021111
DomainFrizzled

FZD1 FZD7 FZD2 FZD3

9.67e-1011264IPR000539
DomainFrizzled

FZD1 FZD7 FZD2 FZD3

9.67e-1011264PF01534
DomainFrizzled

FZD1 FZD7 FZD2 FZD3

9.67e-1011264SM01330
DomainFrizzled/SFRP

FZD1 FZD7 FZD2 FZD3

5.31e-0916264IPR015526
DomainFRI

FZD1 FZD7 FZD2 FZD3

1.41e-0820264SM00063
Domain-

FZD1 FZD7 FZD2 FZD3

1.74e-08212641.10.2000.10
DomainFrizzled_dom

FZD1 FZD7 FZD2 FZD3

3.08e-0824264IPR020067
DomainFZ

FZD1 FZD7 FZD2 FZD3

3.08e-0824264PS50038
DomainFz

FZD1 FZD7 FZD2 FZD3

3.08e-0824264PF01392
DomainGPCR_2-like

FZD1 FZD7 FZD2 FZD3

1.36e-0660264IPR017981
DomainGPCR_2_secretin-like

FZD1 FZD7 FZD2 FZD3

1.36e-0660264IPR000832
DomainG_PROTEIN_RECEP_F2_4

FZD1 FZD7 FZD2 FZD3

1.46e-0661264PS50261
DomainPiezo

PIEZO2 PIEZO1

1.86e-062262IPR027272
DomainPiezo_dom

PIEZO2 PIEZO1

1.86e-062262IPR031805
DomainPiezo_RRas_bdg

PIEZO2 PIEZO1

1.86e-062262PF12166
DomainPIEZO

PIEZO2 PIEZO1

1.86e-062262PF15917
DomainPiezo_RRas-bd_dom

PIEZO2 PIEZO1

1.86e-062262IPR031334
DomainTB2_DP1_HVA22

REEP1 REEP2

2.79e-056262IPR004345
DomainTB2_DP1_HVA22

REEP1 REEP2

2.79e-056262PF03134
Domainzf-DHHC

ZDHHC20 ZDHHC6

4.63e-0423262PF01529
DomainDHHC

ZDHHC20 ZDHHC6

5.48e-0425262PS50216
DomainZnf_DHHC_palmitoyltrfase

ZDHHC20 ZDHHC6

5.48e-0425262IPR001594
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

FZD1 FZD7 FZD2 FZD3

1.85e-0914184M47834
PathwayKEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY

FZD1 FZD7 FZD2 FZD3

3.35e-0916184M47823
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO

FZD1 FZD7 FZD2 FZD3

7.13e-0919184M47833
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 FZD7 FZD2 FZD3

1.07e-0736184M39699
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

FZD1 FZD7 FZD2 FZD3

2.45e-0744184MM15878
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD2 FZD3

2.68e-0745184M47412
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD2 FZD3

2.94e-0746184M47409
PathwayKEGG_BASAL_CELL_CARCINOMA

FZD1 FZD7 FZD2 FZD3

6.09e-0755184M17807
PathwayREACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

FZD1 FZD7 FZD2 FZD3

8.68e-0760184MM15150
PathwayWP_WNT_SIGNALING

FZD1 FZD7 FZD2 FZD3

9.28e-0761184MM15893
PathwayREACTOME_ASYMMETRIC_LOCALIZATION_OF_PCP_PROTEINS

FZD1 FZD7 FZD2 FZD3

1.13e-0664184M27396
PathwayWP_PHYSICOCHEMICAL_FEATURES_AND_TOXICITYASSOCIATED_PATHWAYS

FZD1 FZD7 FZD2 FZD3

1.28e-0666184M39642
PathwayREACTOME_PCP_CE_PATHWAY

FZD1 FZD7 FZD2 FZD3

3.53e-0685184MM15041
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

FZD1 FZD7 FZD2 FZD3

3.53e-0685184M48315
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

FZD1 FZD7 FZD2 FZD3

4.25e-0689184M39563
PathwayWNT_SIGNALING

FZD1 FZD7 FZD2 FZD3

4.25e-0689184M5493
PathwayREACTOME_PCP_CE_PATHWAY

FZD1 FZD7 FZD2 FZD3

4.85e-0692184M27322
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

FZD1 FZD7 FZD2 FZD3

5.28e-0694184M797
PathwayPID_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD2

5.61e-0628183M77
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

FZD1 FZD7 FZD2 FZD3

6.24e-0698184M39731
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

FZD1 FZD7 FZD2 FZD3

7.03e-06101184MM15829
PathwayKEGG_MELANOGENESIS

FZD1 FZD7 FZD2 FZD3

7.03e-06101184M7761
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

FZD1 FZD7 FZD2 FZD3

7.03e-06101184M39387
PathwayPID_WNT_NONCANONICAL_PATHWAY

FZD7 FLNA FZD2

8.47e-0632183M23
PathwayWP_WNT_SIGNALING_WP428

FZD1 FZD7 FZD2 FZD3

1.10e-05113184M39669
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

FZD1 FZD7 FZD2 FZD3

1.22e-05116184MM15863
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

FZD1 FZD7 FZD2 FZD3

1.26e-05117184M39530
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

FZD1 FZD7 FZD2 FZD3

1.30e-05118184M39852
PathwayWP_ALZHEIMERS_DISEASE

FZD1 FZD7 GRIN1 FZD2 FZD3

1.47e-05261185M42565
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

FZD1 FZD7 FZD2 FZD3

1.54e-05123184MM14988
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

FZD1 FZD7 FZD2 FZD3

3.02e-05146184M27288
PathwayKEGG_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD2 FZD3

3.44e-05151184M19428
PathwayWP_BREAST_CANCER_PATHWAY

FZD1 FZD7 FZD2 FZD3

3.72e-05154184M39739
PathwayWP_ALZHEIMERS_DISEASE_AND_MIRNA_EFFECTS

FZD1 FZD7 GRIN1 FZD2 FZD3

4.29e-05326185M39379
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

FZD1 FZD7 FZD2 FZD3

4.43e-05161184M39770
PathwayREACTOME_SIGNALING_BY_WNT

FZD1 FZD7 FZD2 FZD3

2.04e-04239184MM14756
PathwayWP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS

FZD1 FZD7

2.07e-0417182M39525
PathwayREACTOME_GPCR_LIGAND_BINDING

FZD1 OPN1LW FZD7 FZD2 FZD3

2.25e-04463185M507
PathwayWP_GPCRS_OTHER

FZD1 FZD7 FZD2

2.32e-0496183MM15939
PathwayWP_GPCRS_NONODORANT

FZD1 FZD7 FZD2 FZD3

3.08e-04266184MM15843
PathwayWP_WNT_SIGNALING_PATHWAY

FZD1 FZD7 FZD2

3.46e-04110183MM15977
PathwayKEGG_PATHWAYS_IN_CANCER

FZD1 FZD7 FZD2 FZD3

6.57e-04325184M12868
PathwayREACTOME_SIGNALING_BY_WNT

FZD1 FZD7 FZD2 FZD3

6.96e-04330184M7847
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD1 FZD2

7.01e-0431182M27400
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD1 FZD2

7.01e-0431182MM15154
PathwayREACTOME_CA2_PATHWAY

FZD2 FZD3

1.48e-0345182MM15040
PathwayREACTOME_SIGNALING_BY_GPCR

FZD1 OPN1LW FZD7 FZD2 FZD3

1.50e-03702185M746
PathwayWP_PLEURAL_MESOTHELIOMA

FZD1 FZD7 FZD2 FZD3

2.01e-03439184M42563
PathwayREACTOME_CA2_PATHWAY

FZD2 FZD3

2.78e-0362182M27321
PathwayWP_CANCER_PATHWAYS

FZD1 FZD7 FZD2 FZD3

3.38e-03507184M48302
PathwayWP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY

FZD1 FZD2

6.94e-0399182MM15905
PathwayWP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY

FZD1 FZD2

7.64e-03104182M39625
Pubmed

Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.

FZD1 FZD7 FZD2 FZD3

1.71e-11826419388021
Pubmed

Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.

FZD1 FZD7 FZD2 FZD3

5.14e-111026417532316
Pubmed

Expression of Frizzled genes in developing and postnatal hair follicles.

FZD1 FZD7 FZD2 FZD3

5.14e-111026415245425
Pubmed

Molecular determinants of WNT9b responsiveness in nephron progenitor cells.

FZD1 FZD7 FZD2 FZD3

8.07e-111126430978219
Pubmed

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.

FZD1 FZD7 FZD2 FZD3

8.07e-111126424860427
Pubmed

Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.

FZD1 FZD7 FZD2 FZD3

8.07e-111126417582687
Pubmed

Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling.

FZD1 FZD7 FZD2 FZD3

8.07e-111126417576136
Pubmed

Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7.

FZD1 FZD7 FZD2

3.71e-1032639813155
Pubmed

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.

FZD1 FZD7 FZD2

3.71e-10326327680706
Pubmed

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.

FZD1 FZD7 FZD2 FZD3

9.44e-101926421623369
Pubmed

Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.

FZD1 FZD7 FZD2 FZD3

1.78e-092226417064353
Pubmed

A role for Wnt/beta-catenin signaling in lens epithelial differentiation.

FZD1 FZD7 FZD2 FZD3

3.07e-092526412812787
Pubmed

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).

FZD1 FZD7 FZD2 FZD3

5.75e-092926418364260
Pubmed

Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling.

FZD7 FZD2 FZD3

7.41e-09626320802536
Pubmed

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways.

FZD1 FZD7 FZD2

7.41e-09626336867021
Pubmed

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.

FZD1 FZD7 FZD2 FZD3

1.42e-083626424151333
Pubmed

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

FZD1 FZD7 FZD2 FZD3

1.59e-083726415342465
Pubmed

Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.

FZD1 FZD7 FZD2 FZD3

1.59e-083726418800919
Pubmed

Tissue-specific requirements of beta-catenin in external genitalia development.

FZD1 FZD7 FZD2 FZD3

1.78e-083826418635608
Pubmed

Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.

FZD1 FZD7 FZD2 FZD3

1.78e-083826421041481
Pubmed

Differential expression of the Wnt putative receptors Frizzled during mouse somitogenesis.

FZD1 FZD7 FZD3

2.07e-08826310559494
Pubmed

Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95.

FZD1 FZD7 FZD2

3.11e-08926312067714
Pubmed

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

FZD1 FZD7 FZD2

3.11e-0892639707618
Pubmed

Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes.

FZD1 FZD7 FZD2

3.11e-08926323095888
Pubmed

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

FZD1 FZD7 FZD2 FZD3

4.28e-084726428813421
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

FZD1 FZD7 FZD2 FZD3

4.28e-084726433141892
Pubmed

Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.

FZD1 FZD7 FZD2 FZD3

4.28e-084726418351675
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

FZD1 FZD7 FZD2 FZD3

5.08e-084926419562671
Pubmed

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.

FZD1 FZD7 FZD2 FZD3

5.52e-085026427510977
Pubmed

Partial interchangeability of Fz3 and Fz6 in tissue polarity signaling for epithelial orientation and axon growth and guidance.

FZD1 FZD2 FZD3

6.09e-081126325294940
Pubmed

Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development.

FZD1 FZD7 FZD2

1.06e-071326321246654
Pubmed

Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung.

FZD7 FZD2 FZD3

1.68e-071526315617677
Pubmed

Cooperative and independent functions of FGF and Wnt signaling during early inner ear development.

FZD1 FZD7 FZD3

2.50e-071726326443994
Pubmed

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

FZD1 FZD7 FZD2

2.50e-071726328733458
Pubmed

Piezo proteins: incidence and abundance in the enteric nervous system. Is there a link with mechanosensitivity?

PIEZO2 PIEZO1

5.37e-07226230324494
Pubmed

Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts.

FZD1 FZD2

5.37e-07226220189955
Pubmed

[Feeling the pressure? Identification of two proteins activated by mechanical forces].

PIEZO2 PIEZO1

5.37e-07226221299953
Pubmed

Mechanosensitive channels: in touch with Piezo.

PIEZO2 PIEZO1

5.37e-07226221056836
Pubmed

Loss of stretch-activated channels, PIEZOs, accelerates non-small cell lung cancer progression and cell migration.

PIEZO2 PIEZO1

5.37e-07226230745454
Pubmed

The role of PIEZO ion channels in the musculoskeletal system.

PIEZO2 PIEZO1

5.37e-07226236717101
Pubmed

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.

PIEZO2 PIEZO1

5.37e-07226238395992
Pubmed

Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.

PIEZO2 PIEZO1

5.37e-07226237820892
Pubmed

Astrocytes in the optic nerve head express putative mechanosensitive channels.

PIEZO2 PIEZO1

5.37e-07226226236150
Pubmed

Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels.

PIEZO2 PIEZO1

5.37e-07226227743844
Pubmed

Axonal and Glial PIEZO1 and PIEZO2 Immunoreactivity in Human Clitoral Krause's Corpuscles.

PIEZO2 PIEZO1

5.37e-07226238928429
Pubmed

Mechanisms of mechanotransduction and physiological roles of PIEZO channels.

PIEZO2 PIEZO1

5.37e-07226239251883
Pubmed

A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels.

PIEZO2 PIEZO1

5.37e-07226230628892
Pubmed

Piezo1 ion channel pore properties are dictated by C-terminal region.

PIEZO2 PIEZO1

5.37e-07226226008989
Pubmed

Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament.

PIEZO2 PIEZO1

5.37e-07226237975162
Pubmed

Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.

PIEZO2 PIEZO1

5.37e-07226220813920
Pubmed

Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels.

PIEZO2 PIEZO1

5.37e-07226228636944
Pubmed

A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.

PIEZO2 PIEZO1

5.37e-07226232142647
Pubmed

Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception.

PIEZO2 PIEZO1

5.37e-07226234464353
Pubmed

REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues.

REEP1 REEP2

5.37e-07226224355597
Pubmed

Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling.

FLNA PIEZO1

5.37e-07226226526998
Pubmed

Piezo channels: from structure to function.

PIEZO2 PIEZO1

5.37e-07226225037583
Pubmed

Motor neurons with axial muscle projections specified by Wnt4/5 signaling.

FZD7 FZD2 FZD3

5.66e-072226319285468
Pubmed

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

FZD1 FZD7 FZD2 FZD3

6.00e-079026419515997
Pubmed

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

FZD7 FZD2 FZD3

7.43e-07242639096311
Pubmed

A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

FZD7 FZD2 FZD3

7.43e-07242638626800
Pubmed

Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.

FZD1 FZD7 FZD3

1.07e-062726317804636
Pubmed

RNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis.

TLR7 PIEZO1

1.61e-06326232640190
Pubmed

Exploring Piezo1, Piezo2, and TMEM150C in human brain tissues and their correlation with brain biomechanical characteristics.

PIEZO2 PIEZO1

1.61e-06326238124148
Pubmed

Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons.

PIEZO2 PIEZO1

1.61e-06326229521261
Pubmed

PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex.

PIEZO2 PIEZO1

1.61e-06326230361375
Pubmed

Piezo1, a mechanically activated ion channel, is required for vascular development in mice.

PIEZO2 PIEZO1

1.61e-06326224958852
Pubmed

Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters.

FZD1 FZD7

1.61e-06326235296808
Pubmed

Labeling PIEZO2 activity in the peripheral nervous system.

PIEZO2 PIEZO1

1.61e-06326237321223
Pubmed

REEPs are membrane shaping adapter proteins that modulate specific g protein-coupled receptor trafficking by affecting ER cargo capacity.

REEP1 REEP2

1.61e-06326224098485
Pubmed

Mechanically Activated Piezo Channels Mediate Touch and Suppress Acute Mechanical Pain Response in Mice.

PIEZO2 PIEZO1

1.61e-06326230726728
Pubmed

Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.

PIEZO2 PIEZO1

1.61e-06326235650194
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

FZD1 FZD7 FZD2 FZD3

1.72e-0611726417145500
Pubmed

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

FZD7 FZD2 FZD3

2.60e-063626312412008
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

FZD1 FZD7 FZD3

2.83e-063726335831952
Pubmed

Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.

PIEZO2 PIEZO1

3.22e-06426227893727
Pubmed

Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity.

PIEZO2 PIEZO1

3.22e-06426236563677
Pubmed

Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells.

FZD1 FZD2

3.22e-06426218929644
Pubmed

Piezo mechanosensory channels regulate centrosome integrity and mitotic entry.

PIEZO2 PIEZO1

3.22e-06426236574677
Pubmed

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2.

FZD7 FZD2

3.22e-06426218215320
Pubmed

Palmitoylation of SARS-CoV-2 Envelope protein is central to virus particle formation.

ZDHHC20 ZDHHC6

5.37e-06526239287388
Pubmed

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling.

FZD7 FZD3

5.37e-06526218256285
Pubmed

Non-association between polymorphisms of the frizzled receptor genes and bone mineral density in postmenopausal Korean women.

FZD1 FZD7

5.37e-06526219543507
Pubmed

Piezo1 and Piezo2 foster mechanical gating of K2P channels.

PIEZO2 PIEZO1

5.37e-06526234852225
Pubmed

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner.

FZD7 FZD3

5.37e-06526210395542
Pubmed

Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity.

PIEZO2 PIEZO1

5.37e-06526236323321
Pubmed

WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth.

FZD1 FZD2 FZD3

7.10e-065026318351662
Pubmed

Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact.

PIEZO2 PIEZO1

1.13e-05726238733989
Pubmed

Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R).

FZD1 FZD7

1.13e-05726215370539
Pubmed

Myocilin is a modulator of Wnt signaling.

FZD1 FZD7

1.13e-05726219188438
Pubmed

Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.

FZD1 FZD7

1.13e-05726215923619
Pubmed

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.

FZD7 FZD3

1.13e-0572629192640
Pubmed

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.

FZD7 FZD2 FZD3

1.50e-056426324431302
Pubmed

The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell.

PIEZO2 PIEZO1

1.50e-05826238228630
Pubmed

Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors.

PIEZO2 PIEZO1

1.50e-05826227161260
Pubmed

Piezo1 and Piezo2 collectively regulate jawbone development.

PIEZO2 PIEZO1

1.50e-05826238619396
Pubmed

TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection.

PIEZO2 PIEZO1

1.50e-05826234112781
Pubmed

Comparative mapping of the actin-binding protein 280 genes in human and mouse.

OPN1LW FLNA

1.93e-0592628088838
Pubmed

A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells.

FZD7 FZD3

1.93e-0592629160667
Pubmed

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells.

FZD2 FZD3

1.93e-05926219038973
Pubmed

Inherited ACTH insensitivity illuminates the mechanisms of ACTH action.

REEP1 REEP2

2.41e-051026216271481
InteractionSCGB1C1 interactions

FZD1 FZD7 FZD2

5.41e-0713263int:SCGB1C1
InteractionUPK1A interactions

FZD1 FZD7 TMEM164 FZD2 FZD3

1.24e-06150265int:UPK1A
InteractionVNN2 interactions

FZD7 FZD2 FZD3

3.38e-0549263int:VNN2
InteractionTTYH1 interactions

FZD7 TMEM164 WWOX FZD2 PIEZO1

3.60e-05300265int:TTYH1
InteractionTMEM169 interactions

FZD2 FZD3 REEP2

1.16e-0474263int:TMEM169
InteractionGPR21 interactions

TMEM164 FZD2 FZD3

1.52e-0481263int:GPR21
InteractionDLG2 interactions

FZD1 FZD7 GRIN1

1.64e-0483263int:DLG2
Cytoband7p12.3

ABCA13 PKD1L1

7.07e-05222627p12.3
CytobandEnsembl 112 genes in cytogenetic band chr7p12

ABCA13 PKD1L1

5.90e-0463262chr7p12
CytobandXq28

OPN1LW FLNA

4.47e-03176262Xq28
CytobandEnsembl 112 genes in cytogenetic band chrXq28

OPN1LW FLNA

6.47e-03213262chrXq28
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD1 FZD7 FZD2 FZD3

2.86e-1011194286
GeneFamilyReceptor accessory proteins

REEP1 REEP2

1.57e-056192717
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC20 ZDHHC6

2.85e-042419276
GeneFamilySolute carriers

SLC24A3 SLC5A10 SLC48A1

7.73e-03395193752
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

FZD1 FZD7 FZD2 FZD3

9.21e-06135264M5825
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

FADS2 SLC24A3 FLNA PIEZO2 TMEM164 FZD2 PIEZO1

2.23e-05773257gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FZD1 FZD7 FLNA REEP1

2.01e-06157264b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TSPAN12 PIEZO2 REEP1 REEP2

3.02e-06174264cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCellfacs-Skin-nan-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 FZD2 FZD3 TAFA1

3.09e-06175264f1166b567bca80dac3abe90c3dc544c831006640
ToppCellfacs-Kidney-nan-3m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD PIEZO2 ABCA13

3.61e-061822644c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD GRIN1 REEP1 ABCA13

3.61e-06182264b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD GRIN1 REEP1 ABCA13

3.61e-06182264cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD7 FADS2 UMOD ABCA13

3.69e-061832649a2cd63af5f492d46ce80ca1536312e8ac0e7df4
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD7 FZD2 FZD3

4.56e-06193264eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD7 FZD2 FZD3

4.65e-061942645d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FZD1 FZD7 FLNA PIEZO2

4.94e-06197264bc6c530330907a5ec823cc243c8e9c9e340cfb9c
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FZD1 FZD7 FLNA PIEZO2

4.94e-0619726477fe092aae8f05fe137680506892d2f61071d6ea
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ZDHHC20 SLC48A1 PKD1L1

1.08e-0574263a53f2e1f1044f3745a1eff5ba6275c8f1fbf3ae0
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ZDHHC20 SLC48A1 PKD1L1

1.08e-0574263ae547cb8bbd780b19d9c6b555c27dad932dcc753
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TSPAN12 PIEZO2 ABCA13

5.97e-051312639ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FZD1 FADS2 FZD2

7.75e-051432635a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FZD1 FZD7 PIEZO2

7.91e-051442631c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FZD1 FADS2 FZD2

8.07e-05145263997bd540c43725a85ca97e4b79ebe0d336860287
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC24A3 FLNA REEP1

9.47e-05153263ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FZD1 FZD7 SLC24A3

1.08e-041602638a4746463ca1976f7d6de803496c851249ced797
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FZD2 REEP2

1.23e-041672634e58f9bf1e9d47720c871776ec34513ded4de9b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FZD2 REEP2

1.23e-041672634ae9f2c5df13463709ea880ab035965fd99e7626
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.34e-0417226387a30a219b0a6979abb5fba292a2d8ea946fd849
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.34e-041722635030ac31709cac236bb58f4ef9d545d24690411a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FZD1 UMOD FLNA

1.36e-04173263ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FZD1 UMOD FLNA

1.36e-04173263b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 REEP1 PIEZO1

1.48e-04178263ad3de3e03a401dac64431a541899445262246347
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FZD7 PIEZO2 FZD2

1.48e-04178263cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD7 SLC24A3 FLNA

1.51e-04179263e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.53e-041802630b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC24A3 PIEZO2 TAFA1

1.53e-0418026308ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC24A3 PIEZO2 TAFA1

1.53e-041802639b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 REEP1 PIEZO1

1.58e-0418226341b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 REEP1 PIEZO1

1.58e-041822635e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 REEP1 PIEZO1

1.58e-04182263b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.61e-041832636b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCellMS-matDC|MS / Condition, Cell_class and T cell subcluster

TSPAN12 FZD7 GRIN1

1.66e-0418526346bd897349598d85e718e25f9a045d2247723c61
ToppCellMS-matDC-|MS / Condition, Cell_class and T cell subcluster

TSPAN12 FZD7 GRIN1

1.66e-041852639fbe70d3a7b106fb31e13b7f95029785f28ca6f4
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.66e-04185263af86e75096c1812ae27a78405355957ee8043d84
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FZD1 SLC24A3 TAFA1

1.69e-041862638915436d09775f2828a7678af203b1082b36e21c
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 PIEZO2 SLC48A1

1.69e-041862639d6cb36aa0aae69fe584dad31deafcfdcc9fd1db
ToppCell10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 PIEZO2 REEP1

1.69e-04186263e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD3 TAFA1

1.69e-04186263d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 REEP1 PIEZO1

1.69e-0418626320340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellP15-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 SLC48A1

1.71e-0418726360f41b1f1b656d211b80398aa2cf0ac0cdad9372
ToppCellP15-Endothelial-unknown_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 SLC48A1

1.71e-04187263d543ddc63f864b6d0982c4ff652af174af085c4a
ToppCellP03-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 REEP1

1.71e-0418726355618ceec367c1c51ed5c447063d7fbd5c7e0808
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 PIEZO2 REEP1

1.74e-04188263db0652f000d459493321b53239326706eace598c
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

SLC24A3 FLNA REEP1

1.74e-0418826334e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 FZD7 FADS2

1.74e-041882635b69de5baaac45a6d4daa1dbfcb70a7b2ae744ac
ToppCellP15-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 SLC48A1

1.74e-04188263c0a03e33027f52b5c25ffbc8f822128e5160ed20
ToppCelldroplet-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 PIEZO2 REEP1

1.77e-041892637b6cb745c0a637d6addc105a79059ed488fced39
ToppCellP07-Endothelial-unknown_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 REEP1

1.77e-04189263f515a04ae1746257d4568cea13a3dd75b4b05275
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FZD7 FLNA REEP1

1.77e-041892630abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCellP07-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 REEP1

1.77e-04189263fcfb28bd96471affc13e55aa7228f594aaa967cd
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD3 TAFA1

1.79e-04190263ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC24A3 FLNA REEP1

1.79e-041902632e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellP07-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 REEP1

1.79e-041902635d25e40bc2cca314f4265e4001a546e6d99e2a79
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC24A3 FLNA REEP1

1.79e-04190263f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellmegakaryocytic-CD34+_Megakaryoblast|World / Lineage and Cell class

FADS2 SLC24A3 PIEZO2

1.79e-041902631d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCellfacs-Marrow-KLS-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 ZDHHC6 PIEZO1

1.79e-04190263c03c735a0ed850bf460a1847f5e2dd61753e577d
ToppCellP03-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 REEP1

1.79e-04190263347c7bf67ade235a4e2320db6a75ce0dab8744f9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC24A3 FLNA REEP1

1.79e-04190263562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC24A3 FLNA REEP1

1.79e-041902630028f886c789ba238c031eae5d96acaed4af8c25
ToppCellP03-Endothelial-unknown_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TSPAN12 PIEZO2 REEP1

1.79e-041902630c7da05fbd3f095dde7550585209c056f0b76990
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 FZD3 TAFA1

1.79e-041902634971857eac9af17d66d673ed2ab7072639f60a10
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN12 PIEZO2 REEP1

1.82e-04191263718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.82e-041912635a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.82e-0419126378bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN12 PIEZO2 REEP1

1.82e-04191263454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 PIEZO2 REEP1

1.82e-04191263df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.82e-04191263297bc79adc5fef211497819b4861b52cd26ac754
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 PIEZO2 SLC48A1

1.82e-0419126340e617d3c93f03ae87baf6c0b2304b617f5fe782
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FADS2 TLR7 GRIN1

1.82e-041912633e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FADS2 TLR7 GRIN1

1.82e-04191263bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 PIEZO2 REEP1

1.82e-04191263dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FADS2 TLR7 GRIN1

1.82e-04191263989bf108c7f2c78dd7f14481570f1819673a5469
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 PIEZO2 REEP1

1.82e-04191263cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.82e-04191263e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 FZD7 FADS2

1.82e-041912637411b253b16e4d472be0925dee49188f0fd6b0b5
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FADS2 TLR7 GRIN1

1.85e-04192263d9ff2293358c8b031ba212021012e058014ff472
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN12 PIEZO2 SLC48A1

1.85e-041922639a1aeac3ecf31f865a23d8ee15a82aef31779089
ToppCellSevere_COVID-19-Myeloid-pDC|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

FADS2 TLR7 GRIN1

1.85e-04192263f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN12 PIEZO2 REEP1

1.85e-041922632360824910cd471c8286ca369ba144d90d984602
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FADS2 TLR7 GRIN1

1.85e-041922632e8611d65090e39f1a6e74c972288e7b68376d15
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC24A3 FLNA REEP1

1.85e-04192263eb9a0b3d32f90f8b95905c740aab21639dae5cbd
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.85e-0419226361c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 UMOD ABCA13

1.85e-04192263e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN12 PIEZO2 SLC48A1

1.85e-0419226353d438e35c14e7656585942b788459e6d843c555
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PIEZO2 REEP1 PIEZO1

1.85e-04192263cbe57cda44232b183821ac633b60a2668265e616
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 PIEZO2 REEP1

1.85e-04192263ff435141329e3e29fa9b08a4d5b2f55074e7f9ab
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 PIEZO2 REEP1

1.85e-04192263f094ac378e635cf5820e8a8b7a0152073a51ceae
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FADS2 TLR7 GRIN1

1.85e-0419226343569726df281eebe57499e0993b9fd9d36118c2
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZDHHC20 PIEZO2 SLC48A1

1.85e-041922638dc3016601148243196e925641c9507e9d58c9e0
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC24A3 FLNA REEP1

1.88e-04193263173f1d83133f5ffa88e2a75d28835ad7acd2aa90
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC24A3 FLNA REEP1

1.88e-04193263b1893193766ae41bf2ab6ed4083285c9c814e608
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 PIEZO2 REEP1

1.88e-0419326325129080f8a40b2988a5d9dfec36ff9e72c27e61
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN12 FLNA REEP1

1.88e-04193263a402e736440684ebe123673b6b0c6fcd8fa057b2
ToppCelldroplet-Lung-nan-21m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 PIEZO2 REEP1

1.88e-04193263ffdcbc5caff7fd4cc2e83dd21a05d43b0593d542
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FZD1 FZD7 FLNA

1.88e-041932632f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN12 PIEZO2 REEP1

1.88e-04193263ac1073bf4d3868841226b850b058f1e27326a14e
DrugA 172

FZD1 FZD7 FZD2 FZD3

1.16e-0670264CID000014025
DrugDextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; PC3; HT_HG-U133A

TSPAN12 FADS2 UMOD WWOX SLC48A1

2.68e-061982656300_UP
Drugclofazimine

FZD1 FZD7 FZD2

8.44e-0635263CID000002794
Drug3-hydroxyretinal

OPN1LW WWOX

1.88e-056262CID000151436
DrugSecurinine [5610-40-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A

FZD7 FADS2 GRIN1 SLC48A1

5.60e-051862646831_UP
DrugDigoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A

FZD1 FADS2 SLC24A3 SLC48A1

6.86e-051962643397_DN
Drugtroglitazone; Down 200; 10uM; MCF7; HT_HG-U133A

FADS2 SLC24A3 REEP1 SLC48A1

7.00e-051972645592_DN
Drug2-propylpentanoic acid; Down 200; 500uM; HL60; HT_HG-U133A

FADS2 FLNA TMEM164 WWOX

7.00e-051972641181_DN
Drug0198306-0000 [212631-61-3]; Up 200; 10uM; MCF7; HT_HG-U133A

SLC24A3 WWOX REEP1 SLC48A1

7.14e-051982647064_UP
DrugSolasodine [126-17-0]; Up 200; 9.6uM; PC3; HT_HG-U133A

FZD1 SLC24A3 GRIN1 SLC48A1

7.14e-051982643749_UP
DrugDipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A

FADS2 SLC48A1 PIEZO1 DNAI2

7.28e-051992642744_UP
Diseaselysophosphatidylcholine 22:6 measurement

FZD7 FADS2 WWOX

4.91e-0718263EFO_0010365
Diseasehereditary spastic paraplegia 31 (implicated_via_orthology)

REEP1 REEP2

1.12e-056262DOID:0110782 (implicated_via_orthology)
Diseasemetabolite measurement, body weight gain

FADS2 DNAI2

4.90e-0512262EFO_0004566, EFO_0004725
Diseaseeicosapentaenoate EPA; 20:5n3 measurement

FZD1 FADS2

1.01e-0417262EFO_0021049
DiseaseEpileptic encephalopathy

FLNA GRIN1

3.20e-0430262C0543888
Diseaselysophosphatidylethanolamine 18:1 measurement

FADS2 SLC24A3

4.12e-0434262EFO_0010368

Protein segments in the cluster

PeptideGeneStartEntry
FMSIHCTVSWLQMWT

ABCA13

1141

Q86UQ4
MWTKYHMAYLTDAAW

DNAI2

401

Q9GZS0
WVYHLTSVWMIFVVT

OPN1LW

51

P04000
SHWFVWVTQMNHIVM

FADS2

331

O95864
WTVPSVMLTIDYTWH

KIAA1109

651

Q2LD37
FMMLYFFSMASSIWW

FZD2

331

Q14332
WIAAFSYMMVWMVTI

SLC24A3

486

Q9HC58
WVLVTHVMYMQDYWR

SLC48A1

51

Q6P1K1
FMMLYFFSMASSIWW

FZD1

406

Q9UP38
MVLYFFGMASSIWWV

FZD7

341

O75084
IWTLILHYSISMPMW

FLNA

141

P21333
MILYFFTMAGSVWWV

FZD3

291

Q9NPG1
AWHSMTVWYKMQSVS

PKD1L1

496

Q8TDX9
MAMVSAMSWVLYLWI

TAFA1

1

Q7Z5A9
VTWSIMEFSLWYMNS

MT-ND5

96

P03915
VKWMMYWIIFALFTT

REEP1

36

Q9H902
TMAMIDSVLWYWPLH

ZDHHC6

36

Q9H6R6
FFVMFVWSYWMTIFT

ZDHHC20

61

Q5W0Z9
VKWMMYWIVFAFFTT

REEP2

36

Q9BRK0
LTWMLMVVVASWFIT

UMOD

6

P07911
MTFGLTIMATWYWCT

SLC5A10

266

A0PJK1
WYRIWASGHQTLMTM

TMEM164

251

Q5U3C3
IAMMAWSITYHSWLT

PIEZO2

506

Q9H5I5
MMYSNIHRSWWVYTL

WWOX

326

Q9NZC7
FWLMSISVLAVSAWM

TSPAN12

21

O95859
MMTASHLYFWDVWYI

TLR7

856

Q9NYK1
MMVWSITYHSWLTFV

PIEZO1

431

Q92508
HQSSVWFEMMRVYSW

GRIN1

146

Q05586
WFEMMRVYSWNHIIL

GRIN1

151

Q05586