Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	kinase binding	FLNA ALKAL1 ANK2 GIT1 PSG4 SGK1 PTPN23 TNS2 NBEA JAKMIP3 SPDYE18 KIF20A DACT1 PER2 MICAL2 HSPB6 PKD1 SPDYE2 SPDYE21 DLG3 AKAP11 SPDYE5 TNFAIP3 SPDYE2B MAP2K6 SPDYE6 SPDYE16	3.13e-08	969	166	27	GO:0019900
GeneOntologyMolecularFunction	protein kinase binding	FLNA ALKAL1 ANK2 GIT1 PSG4 SGK1 PTPN23 TNS2 NBEA SPDYE18 KIF20A DACT1 MICAL2 HSPB6 PKD1 SPDYE2 SPDYE21 DLG3 AKAP11 SPDYE5 SPDYE2B MAP2K6 SPDYE6 SPDYE16	2.56e-07	873	166	24	GO:0019901
GeneOntologyMolecularFunction	acetylcholine receptor regulator activity	SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	2.60e-06	27	166	5	GO:0030548
GeneOntologyMolecularFunction	neurotransmitter receptor regulator activity	SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.15e-06	28	166	5	GO:0099602
GeneOntologyMolecularFunction	lactoperoxidase activity	PXDN PXDNL	4.08e-04	4	166	2	GO:0140825
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein serine/threonine kinase activity	STIL SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.60e-08	25	164	6	GO:0045737
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein kinase activity	STIL SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	7.51e-08	28	164	6	GO:1904031
GeneOntologyBiologicalProcess	regulation of cell cycle	MIIP ZWILCH MBTD1 ATR GIT1 CEP76 INO80 STIL PPM1A KIF20A DACT1 NEK1 CSF1R PER2 ARID2 MDC1 PKD1 SPDYE2 PRKCQ SPDYE5 TNFAIP3 SPDYE2B MAP2K6 SPDYE6 USP47 SPDYE16	6.75e-06	1256	164	26	GO:0051726
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein serine/threonine kinase activity	STIL SPDYE2 SPDYE5 TNFAIP3 SPDYE2B SPDYE6 SPDYE16	1.16e-05	96	164	7	GO:0000079
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein kinase activity	STIL SPDYE2 SPDYE5 TNFAIP3 SPDYE2B SPDYE6 SPDYE16	1.52e-05	100	164	7	GO:1904029
GeneOntologyBiologicalProcess	DNA repair	MBTD1 RNF168 ATR INO80 TEX15 FANCA LIG4 RIF1 WDHD1 ARID2 EEPD1 MDC1 MLH1 EXO1 NEURL4 USP47	6.21e-05	648	164	16	GO:0006281
GeneOntologyBiologicalProcess	multicellular organismal-level homeostasis	MKKS ABCA3 PSG4 TNS2 IP6K1 NBEA LRRK1 TEX15 NMUR2 KDM6B TBL1XR1 PACS1 CSF1R PER2 TJP1 AKAP11 TNFAIP3 GNAS HBB MAP2K6 SMAD5	8.43e-05	1043	164	21	GO:0048871
GeneOntologyBiologicalProcess	somatic recombination of immunoglobulin genes involved in immune response	RNF168 LIG4 RIF1 MLH1 EXO1	1.15e-04	60	164	5	GO:0002204
GeneOntologyBiologicalProcess	somatic diversification of immunoglobulins involved in immune response	RNF168 LIG4 RIF1 MLH1 EXO1	1.15e-04	60	164	5	GO:0002208
GeneOntologyBiologicalProcess	isotype switching	RNF168 LIG4 RIF1 MLH1 EXO1	1.15e-04	60	164	5	GO:0045190
GeneOntologyBiologicalProcess	B cell activation involved in immune response	RNF168 LIG4 RIF1 MLH1 EXO1 TNFAIP3	1.57e-04	101	164	6	GO:0002312
GeneOntologyBiologicalProcess	positive regulation of protein serine/threonine kinase activity	PSG4 STIL SPDYE2 SPDYE5 SPDYE2B MAP2K6 SPDYE6 SPDYE16	1.60e-04	193	164	8	GO:0071902
GeneOntologyBiologicalProcess	tissue kallikrein-kinin cascade	KLK3 KLK1	1.88e-04	3	164	2	GO:0002255
GeneOntologyBiologicalProcess	somatic recombination of immunoglobulin gene segments	RNF168 LIG4 RIF1 MLH1 EXO1	2.23e-04	69	164	5	GO:0016447
GeneOntologyBiologicalProcess	DNA damage response	MBTD1 RNF168 ATR SGK1 INO80 TEX15 FANCA LIG4 NEK1 RIF1 WDHD1 ARID2 EEPD1 MDC1 MLH1 EXO1 MAP2K6 NEURL4 USP47	2.30e-04	959	164	19	GO:0006974
GeneOntologyBiologicalProcess	regulation of cell cycle phase transition	MIIP ZWILCH ATR INO80 STIL DACT1 NEK1 CSF1R ARID2 MDC1 PKD1 PRKCQ USP47	2.55e-04	516	164	13	GO:1901987
MousePheno	abnormal induced cell death	GLIPR1 RNF168 ATR FANCA IVNS1ABP LIG4 RIF1 PER2 MDC1 MLH1 MAP2K6 USP47	5.93e-06	256	133	12	MP:0008942
Domain	Spy1	SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16	1.86e-10	11	164	6	PF11357
Domain	Speedy	SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16	1.86e-10	11	164	6	IPR020984
Domain	GIT	GIT1 GIT2	7.66e-05	2	164	2	SM00555
Domain	GIT1_C	GIT1 GIT2	7.66e-05	2	164	2	PF12205
Domain	GIT1/2_CC	GIT1 GIT2	7.66e-05	2	164	2	IPR032352
Domain	GIT_SHD	GIT1 GIT2	7.66e-05	2	164	2	PF08518
Domain	GIT_CC	GIT1 GIT2	7.66e-05	2	164	2	PF16559
Domain	GIT1_C	GIT1 GIT2	7.66e-05	2	164	2	IPR022018
Domain	GIT_SHD	GIT1 GIT2	7.66e-05	2	164	2	IPR013724
Domain	AbLIM_anchor	ABLIM3 ABLIM2	4.55e-04	4	164	2	PF16182
Domain	AbLIM_anchor	ABLIM3 ABLIM2	4.55e-04	4	164	2	IPR032402
Pathway	WP_NIPBL_ROLE_IN_DNA_DAMAGE_CORNELIA_DE_LANGE_SYNDROME	RNF168 ATR MDC1	3.35e-05	8	121	3	M42528
Pubmed	Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.	SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.17e-10	9	169	5	36272447
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PTPN23 CC2D1B IP6K1 ABLIM3 ANO8 TRIM66 RFTN1 NEK1 VPS13D PLEKHG3 OSBPL3 ARID2 EEPD1 CNTNAP4 ZNF518B NEURL4	2.91e-09	493	169	16	15368895
Pubmed	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.	SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.18e-09	13	169	5	15611625
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MIIP JCAD GIT1 STIL RAB11FIP1 PPM1A IVNS1ABP NEK1 VPS13D TJP1 PLEKHG3 OSBPL3 EXO1 AKAP11 TNFAIP3 GNAS EIF3I TSC22D4 SRRM2 ARHGAP21	8.67e-09	861	169	20	36931259
Pubmed	Characterization of a new family of cyclin-dependent kinase activators.	SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	1.51e-08	17	169	5	15574121
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	ARRDC1 HAUS5 RIOK3 PALMD RAB11FIP1 NEDD1 TBL1XR1 KIF20A NEK1 GPBP1L1 SMG7 WDHD1 TJP1 CRYBG1 GNAS ARHGAP21 USP47 SMAD5 WDTC1	8.11e-07	1038	169	19	26673895
Pubmed	Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.	ATR FANCA MDC1 MLH1	9.36e-07	16	169	4	27760317
Pubmed	NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response.	ATR NEK1 MDC1	1.12e-06	5	169	3	15604234
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	EPPK1 CHD9 INO80 RRP1 KIF20A RIF1 TJP1 TKT ARID2 RRP12 MDC1	4.01e-06	394	169	11	27248496
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MKKS EPPK1 GIT1 SGK1 RIOK3 GIT2 LRRK1 RAB11FIP1 PPM1A LIG4 PPIG TKT OSBPL3 RRP12 DLG3 AKAP11 GNAS EIF3I SRRM2 NEURL4	4.75e-06	1284	169	20	17353931
Pubmed	SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination.	ATR MDC1 MLH1 SRRM2	8.65e-06	27	169	4	25703348
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	HAUS5 ARID2 NKTR ECI2 PIPSL NEURL4 USP47 WDTC1	1.01e-05	212	169	8	33853758
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF21B HAUS5 HIP1R LRRK1 INO80 KDM6B IVNS1ABP SMG7 MDC1 TMEM131L AKAP11 HOMEZ	1.19e-05	529	169	12	14621295
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	MIIP ZWILCH GIT1 ARRDC1 CHD9 INO80 ABLIM3 RSBN1 LIG4 RIF1 PKD1 MLH1 TNFAIP3 NEURL4 SEZ6 SPDYE16	1.27e-05	925	169	16	28986522
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	HIP1R PTPN23 RSBN1 RIF1 ARID2 FDXR MLH1 TSC22D4 HBB SRRM2 ARHGAP21	2.16e-05	472	169	11	38943005
Pubmed	Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse.	GIT1 GIT2	2.35e-05	2	169	2	26637799
Pubmed	NFBD1/Mdc1 mediates ATR-dependent DNA damage response.	ATR MDC1	2.35e-05	2	169	2	15734998
Pubmed	Novel PKD1 and PKD2 mutations in autosomal dominant polycystic kidney disease (ADPKD).	PDK2 PKD1	2.35e-05	2	169	2	21115670
Pubmed	[Pathophysiology of ulcer disease].	MLH1 EXO1	2.35e-05	2	169	2	2414623
Pubmed	The multifunctional GIT family of proteins.	GIT1 GIT2	2.35e-05	2	169	2	16598076
Pubmed	Filamin A is required for T cell activation mediated by protein kinase C-theta.	FLNA PRKCQ	2.35e-05	2	169	2	16849481
Pubmed	Regulation of human prostate-specific antigen gene expression in transgenic mice: evidence for an enhancer between the PSA and human glandular kallikrein-1 genes.	KLK3 KLK1	2.35e-05	2	169	2	9857240
Pubmed	Epidemiology of autosomal-dominant polycystic kidney disease: an in-depth clinical study for south-western Germany.	PDK2 PKD1	2.35e-05	2	169	2	23300259
Pubmed	Tyrosinekinase inhibition facilitates cooperation of transcription factor SALL4 and ABC transporter A3 towards intrinsic CML cell drug resistance.	ABCA3 SALL4	2.35e-05	2	169	2	23432194
Pubmed	Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.	NBEA DLG3	2.35e-05	2	169	2	22745750
Pubmed	Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues.	GIT1 GIT2	2.35e-05	2	169	2	17565117
Pubmed	ATR-dependent pathways control hEXO1 stability in response to stalled forks.	ATR EXO1	2.35e-05	2	169	2	18048416
Pubmed	Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.	MLH1 EXO1	2.35e-05	2	169	2	14716311
Pubmed	ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background.	ATR MLH1	2.35e-05	2	169	2	15282542
Pubmed	A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair.	MLH1 EXO1	2.35e-05	2	169	2	19420220
Pubmed	Filamin associates with Smads and regulates transforming growth factor-beta signaling.	FLNA SMAD5	2.35e-05	2	169	2	11278410
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLNA ATR GIT1 PACS1 RIF1 PPIG WDHD1 TKT RRP12 MDC1 EXO1 SRRM2 USP47 HOMEZ	2.78e-05	774	169	14	15302935
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	MBTD1 KREMEN1 ANK2 CC2D1B SALL4 DACT1 FREM2 PXDN TJP1 PLEKHG3 ARID2 PKD1 MLH1 EXO1 SP5 TNK2 DLG3 GNAS	2.84e-05	1215	169	18	15146197
Pubmed	Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.	FLNA NBEA RAB11FIP1 TMEM131L	4.74e-05	41	169	4	34638806
Pubmed	The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.	FLNA KLK3 MDC1 PLD1 SRRM2 SMAD5 WDTC1	5.70e-05	199	169	7	36688959
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	JCAD PTPN23 TNS2 NBEA RAB11FIP1 PPM1A PACS1 RFTN1 RIF1 SMG7 KIF15 TJP1 RRP12 MLH1 SRRM2 NEURL4	5.73e-05	1049	169	16	27880917
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GLIPR1 JCAD DCHS2 ANK2 GIT1 CHD9 NBEA JAKMIP3 HUNK KDM6B DSCAML1 PLEKHH1 TRIM66 TJP1 MICAL2 PKD1 ARHGAP21 USP47	5.84e-05	1285	169	18	35914814
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	ATR NEDD1 WDHD1 MDC1 SRRM2	6.12e-05	85	169	5	16051665
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLNA ATR SALL4 PXDN RRP12 CRYBG1 NEURL4	6.26e-05	202	169	7	33005030
Pubmed	Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization.	KLK3 KLK1	7.02e-05	3	169	2	19164804
Pubmed	Regional and global protective effects of tissue kallikrein gene delivery to the peri-infarct myocardium.	KLK3 KLK1	7.02e-05	3	169	2	17465807
Pubmed	Mouse kallikrein arginyl-esteropeptidase genes: analysis of cloned cDNAs suggests rapid functional divergence from a common ancestral sequence.	KLK3 KLK1	7.02e-05	3	169	2	6926406
Pubmed	7S Nerve growth factor alpha and gamma subunits are closely related proteins.	KLK3 KLK1	7.02e-05	3	169	2	6712944
Pubmed	Evolution of the Cdk-activator Speedy/RINGO in vertebrates.	SPDYE2 SPDYE6	7.02e-05	3	169	2	22763696
Pubmed	Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells.	KLK3 KLK1	7.02e-05	3	169	2	21164105
Pubmed	Tissue kallikrein stimulates Ca(2+) reabsorption via PKC-dependent plasma membrane accumulation of TRPV5.	KLK3 KLK1	7.02e-05	3	169	2	17006539
Pubmed	Characterization of mouse glandular kallikrein 24 expressed in testicular Leydig cells.	KLK3 KLK1	7.02e-05	3	169	2	15985384
Pubmed	ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function.	ATR FANCA	7.02e-05	3	169	2	19109555
Pubmed	Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis.	KLK3 KLK1	7.02e-05	3	169	2	17210241
Pubmed	THG-1 suppresses SALL4 degradation to induce stemness genes and tumorsphere formation through antagonizing NRBP1 in squamous cell carcinoma cells.	SALL4 TSC22D4	7.02e-05	3	169	2	31864704
Pubmed	Detection of a kallikrein in the mouse lactating mammary gland: a possible processing enzyme for the epidermal growth factor precursor.	KLK3 KLK1	7.02e-05	3	169	2	7525260
Pubmed	Identification of mK1, a true tissue (glandular) kallikrein of mouse submandibular gland: tissue distribution and a comparison of kinin-releasing activity with other submandibular kallikreins.	KLK3 KLK1	7.02e-05	3	169	2	8188620
Pubmed	Mouse testicular Leydig cells express Klk21, a tissue kallikrein that cleaves fibronectin and IGF-binding protein-3.	KLK3 KLK1	7.02e-05	3	169	2	11606460
Pubmed	The amino acid sequence of the gamma-subunit of mouse submaxillary gland 7 S nerve growth factor.	KLK3 KLK1	7.02e-05	3	169	2	7263706
Pubmed	A cytocidal tissue kallikrein isolated from mouse submandibular glands.	KLK3 KLK1	7.02e-05	3	169	2	2583286
Pubmed	RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.	RNF168 MDC1	7.02e-05	3	169	2	24324146
Pubmed	Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome.	MLH1 EXO1	7.02e-05	3	169	2	12414623
Pubmed	Inducible expression of kallikrein in renal tubular cells protects mice against spontaneous lupus nephritis.	KLK3 KLK1	7.02e-05	3	169	2	23280471
Pubmed	Mouse glandular kallikrein genes. Nucleotide sequence of cloned cDNA coding for a member of the kallikrein arginyl esteropeptidase group of serine proteases.	KLK3 KLK1	7.02e-05	3	169	2	6174512
Pubmed	Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines.	KLK3 KLK1	7.02e-05	3	169	2	18778305
Pubmed	Intense light as anticoagulant therapy in humans.	A1CF PER2	7.02e-05	3	169	2	33382840
Pubmed	Single-chain tissue-type plasminogen activator is a substrate of mouse glandular kallikrein 24.	KLK3 KLK1	7.02e-05	3	169	2	16286722
Pubmed	mGK-6-derived true tissue kallikrein is synthesized, processed, and targeted through a regulated secretory pathway in mouse pituitary AtT-20 cells.	KLK3 KLK1	7.02e-05	3	169	2	1639762
Pubmed	Serendipitous Discovery of T Cell-Produced KLK1b22 as a Regulator of Systemic Metabolism.	KLK3 KLK1	7.02e-05	3	169	2	37358498
Pubmed	EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.	ATR EXO1	7.02e-05	3	169	2	38721777
Pubmed	Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior.	KIF21B NBEA	7.02e-05	3	169	2	29847800
Pubmed	Deletion of kallikrein 1b5 (Klk1b5) has no impact on fertility in mice.	KLK3 KLK1	7.02e-05	3	169	2	30957940
Pubmed	Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation.	KLK3 KLK1	7.02e-05	3	169	2	25628066
Pubmed	A meckelin-filamin A interaction mediates ciliogenesis.	FLNA TJP1	7.02e-05	3	169	2	22121117
Pubmed	Targeting kallikrein 6 proteolysis attenuates CNS inflammatory disease.	KLK3 KLK1	7.02e-05	3	169	2	15033932
Pubmed	Cellular basis for the differential response of mouse kallikrein genes to hormonal induction.	KLK3 KLK1	7.02e-05	3	169	2	3649290
Pubmed	Kallikrein-related peptidases.	KLK3 KLK1	7.02e-05	3	169	2	18344018
Pubmed	Positive selection shaped the convergent evolution of independently expanded kallikrein subfamilies expressed in mouse and rat saliva proteomes.	KLK3 KLK1	7.02e-05	3	169	2	21695125
Pubmed	Uterine artery structural and functional changes during pregnancy in tissue kallikrein-deficient mice.	KLK3 KLK1	7.02e-05	3	169	2	12933530
Pubmed	The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis.	KLK3 KLK1	7.02e-05	3	169	2	19262577
Pubmed	Renin and kallikrein in connecting tubule of mouse.	KLK3 KLK1	7.02e-05	3	169	2	14633138
Pubmed	Sequence of mGK-11, a mouse glandular kallikrein gene.	KLK3 KLK1	7.02e-05	3	169	2	3205728
Pubmed	Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides.	KLK3 KLK1	7.02e-05	3	169	2	6602295
Pubmed	SALL4, a stem cell factor, affects the side population by regulation of the ATP-binding cassette drug transport genes.	ABCA3 SALL4	7.02e-05	3	169	2	21526180
Pubmed	A complete cDNA sequence for the major epidermal growth factor binding protein in the male mouse submandibular gland.	KLK3 KLK1	7.02e-05	3	169	2	3322386
Pubmed	beta-NGF-endopeptidase: structure and activity of a kallikrein encoded by the gene mGK-22.	KLK3 KLK1	7.02e-05	3	169	2	2012805
Pubmed	Kallikrein protects against microalbuminuria in experimental type I diabetes.	KLK3 KLK1	7.02e-05	3	169	2	19516248
Pubmed	Autoimmunity against a tissue kallikrein in IQI/Jic Mice: a model for Sjogren's syndrome.	KLK3 KLK1	7.02e-05	3	169	2	15545270
Pubmed	Mutations in multiple PKD genes may explain early and severe polycystic kidney disease.	HNF1B PKD1	7.02e-05	3	169	2	22034641
Pubmed	Sequence and expression of mouse gamma-renin.	KLK3 KLK1	7.02e-05	3	169	2	3288617
Pubmed	Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis.	RNF168 TNFAIP3	7.02e-05	3	169	2	36944318
Pubmed	Sequence of an epidermal growth factor-binding protein.	KLK3 KLK1	7.02e-05	3	169	2	6330081
Pubmed	Cloning and characterization of mouse klk27, a novel tissue kallikrein expressed in testicular Leydig cells and exhibiting chymotrypsin-like specificity.	KLK3 KLK1	7.02e-05	3	169	2	11082197
Pubmed	Mouse glandular kallikrein genes. Identification, structure, and expression of the renal kallikrein gene.	KLK3 KLK1	7.02e-05	3	169	2	3007510
Pubmed	Role of tissue kallikrein in response to flow in mouse resistance arteries.	KLK3 KLK1	7.02e-05	3	169	2	15126916
Pubmed	The molecular biology of the kallikrein-kinin system: I. General description, nomenclature and the mouse gene family.	KLK3 KLK1	7.02e-05	3	169	2	8228186
Pubmed	The sequence of a cDNA clone coding for a novel kallikrein from mouse submaxillary gland.	KLK3 KLK1	7.02e-05	3	169	2	3636812
Pubmed	Reduction in nerve growth factor availability leads to a conditioning lesion-like effect in sympathetic neurons.	KLK3 KLK1	7.02e-05	3	169	2	16967509
Pubmed	Growth factor-binding proteases in the murine submaxillary gland: isolation of a cDNA clone.	KLK3 KLK1	7.02e-05	3	169	2	11892812
Pubmed	Critical role of SMG7 in activation of the ATR-CHK1 axis in response to genotoxic stress.	ATR SMG7	7.02e-05	3	169	2	33820915
Pubmed	Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice.	KLK3 KLK1	7.02e-05	3	169	2	11226291
Pubmed	Sequence of the mouse glandular kallikrein gene, mGK-5.	KLK3 KLK1	7.02e-05	3	169	2	3502721
Pubmed	Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis.	KLK3 KLK1	7.02e-05	3	169	2	22335454
Pubmed	Isolation of a cDNA clone coding for the gamma-subunit of mouse nerve growth factor using a high-stringency selection procedure.	KLK3 KLK1	7.02e-05	3	169	2	6548955
Pubmed	Interference of kallikrein 1b26 (klk1b26) translation by microRNA specifically expressed in female mouse submandibular glands: an additional mechanism for sexual dimorphism of klk1b26 protein in the glands.	KLK3 KLK1	7.02e-05	3	169	2	22085651
Interaction	YWHAG interactions	MIIP KIF21B JCAD FLNA GIT1 TNS2 GIT2 RAB11FIP1 PACS1 NEK1 PPIG VPS13D GPBP1L1 KIF15 TJP1 PLEKHG3 OSBPL3 HSPB6 EXO1 TNK2 AKAP11 PRKCQ NKTR TNFAIP3 GNAS EIF3I TSC22D4 SRRM2 ARHGAP21 HOMEZ	6.91e-08	1248	163	30	int:YWHAG
Interaction	YWHAZ interactions	MIIP JCAD GIT1 SGK1 HIP1R RAB11FIP1 PPM1A IVNS1ABP PACS1 NEK1 VPS13D GPBP1L1 PER2 KIF15 TJP1 PLEKHG3 TKT OSBPL3 HSPB6 MDC1 EXO1 TNK2 AKAP11 TNFAIP3 EIF3I TSC22D4 ARHGAP21 USP47 HOMEZ	7.58e-07	1319	163	29	int:YWHAZ
Interaction	CEP135 interactions	MIIP JCAD STIL NEDD1 KIF20A DACT1 SMG7 TJP1 TMEM131L PLD1 NEURL4 ARHGAP21	2.28e-06	272	163	12	int:CEP135
Interaction	YWHAH interactions	MIIP KIF21B JCAD EPPK1 GIT1 TNS2 GIT2 STIL RAB11FIP1 IVNS1ABP PACS1 NEK1 VPS13D GPBP1L1 TJP1 PLEKHG3 OSBPL3 EXO1 AKAP11 NKTR TNFAIP3 TSC22D4 SRRM2 ARHGAP21 HOMEZ	2.82e-06	1102	163	25	int:YWHAH
Interaction	YWHAQ interactions	MIIP KIF21B JCAD FLNA EPPK1 SGK1 RAB11FIP1 PPM1A IVNS1ABP NEK1 VPS13D WDHD1 TJP1 PLEKHG3 OSBPL3 EXO1 AKAP11 PRKCQ TNFAIP3 EIF3I HBB ARHGAP21 USP47 HOMEZ	1.15e-05	1118	163	24	int:YWHAQ
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE2 SPDYE5 SPDYE2B SPDYE6	4.22e-07	12	100	4	756
GeneFamily	WD repeat domain containing	KIF21B TBL1Y NBEA NEDD1 TBL1XR1 WDHD1 EIF3I WDTC1	1.03e-04	262	100	8	362
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SALL4 ZNF736 ZNF230 ZNF235 ZNF490 EGR4 SP5 ZNF701 ZNF518B ZNF468 ZNF844	2.05e-03	718	100	11	28
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF20A KIF15	2.10e-03	46	100	3	622
Coexpression	BAE_BRCA1_TARGETS_DN	STIL TJP1 TKT TNFAIP3 SMAD5	1.24e-06	30	167	5	M2073
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_EARLY_STALK_CELL	KIF21B ZWILCH ANK2 SGK1 SALL4 HUNK STIL ANO8 FANCA KIF20A KIF15 WDHD1 MDC1 EXO1 TNFAIP3	3.79e-06	567	167	15	M45692
Coexpression	WILCOX_RESPONSE_TO_PROGESTERONE_UP	SGK1 CEP76 KIF20A RIF1 WDHD1 SC5D TLL2 HBB	6.49e-06	153	167	8	M18058
Coexpression	MATZUK_SPERMATOCYTE	IP6K1 TEX15 FANCA EGR4 MLH1 EXO1	6.75e-06	72	167	6	M1831
Coexpression	MATZUK_SPERMATOCYTE	IP6K1 TEX15 FANCA EGR4 MLH1 EXO1	7.31e-06	73	167	6	MM1234
Coexpression	KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	MKKS MBTD1 RNF168 ARRDC1 HIP1R RIOK3 CHD9 TBL1XR1 IVNS1ABP DACT1 SMG7 TJP1 PLEKHG3 OSBPL3 ARID2 MDC1 PLD1 ARHGAP21	7.84e-06	843	167	18	M2356
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	GLIPR1 KIF21B FLNA ATR SUSD3 GIT2 TBL1XR1 PPM1A IVNS1ABP PACS1 RFTN1 RIF1 PPIG ARID2 GZMM TMEM131L SECISBP2 CRYBG1 TNK2 AKAP11 PRKCQ TNFAIP3 GNAS TSC22D4 USP47	9.06e-06	1492	167	25	M40023
Coexpression	BROWNE_HCMV_INFECTION_48HR_DN	JCAD FLNA PSG4 NEK1 RIF1 PER2 TJP1 MICAL2 HSPB6 MLH1 NKTR HBB MAP2K6	1.40e-05	482	167	13	M12144
Coexpression	GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_UP	MBTD1 SGK1 IP6K1 PACS1 GPBP1L1 GZMM TMEM131L MAP2K6	4.49e-05	200	167	8	M5049
Coexpression	RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP	GLIPR1 ABCA3 KREMEN1 AKNAD1 NBEA PPM1A KIF20A NEK1	5.16e-05	204	167	8	M1844
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MFSD4A SALL4 NBEA RAB11FIP1 ADAM28 PLEKHH1 PER2 NKTR ARHGAP21	2.66e-08	179	167	9	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Biopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ZWILCH HUNK STIL KIF20A KIF15 WDHD1 EXO1 SP5	8.83e-07	199	167	8	4fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SGK1 MFSD4A CHD9 ADAM28 IVNS1ABP PLEKHH1 RIF1 NKTR	8.83e-07	199	167	8	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	LA-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	HNF1B A1CF ZNF230 DACT1 FDXR HBB	1.01e-06	88	167	6	7232b13a9788f89600411222c0d93bdc3788816f
ToppCell	normal_Lymph_Node-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	SGK1 SALL4 KDM6B CSF1R EGR4 TNFAIP3 ARHGAP21	1.84e-06	153	167	7	5424494ea1f09542799045a875cc3eac13de5079
ToppCell	Dividing_Macrophages-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	KIF15 WDHD1 EEPD1 FDXR EXO1 CXorf58 KLK1	3.16e-06	166	167	7	ea95b94ccc2ac67df741b30c27f4ae698925875f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	IPPK FLNA ANO8 PLEKHG3 OSBPL3 GZMM PRKCQ	4.65e-06	176	167	7	5914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CEP76 MUC12 DSCAML1 RRP1 FCGBP KCNC1 KLK1	4.83e-06	177	167	7	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Dendritic_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATR PTPN23 MDC1 GZMM TNK2 KLK1 MAP2K6	5.39e-06	180	167	7	710526abedc8e0f9ba19ad69220df4c9468ada8f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HNF1B ANK2 HUNK DSCAML1 FCGBP OSBPL3 PRKCQ	6.92e-06	187	167	7	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZWILCH STIL ABLIM3 KIF20A KIF15 GZMM PRKCQ	7.68e-06	190	167	7	b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZWILCH STIL FANCA KIF20A KIF15 WDHD1 EXO1	7.68e-06	190	167	7	c3c65d1f24e0ebdbb9adb617bed299a668f423f5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A DSCAML1 IVNS1ABP PXDNL OSBPL3 MYO3B PRKCQ	7.68e-06	190	167	7	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A DSCAML1 IVNS1ABP PXDNL OSBPL3 MYO3B PRKCQ	8.22e-06	192	167	7	562df5e87038c500dd3a003fe5374cb31946b145
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HNF1B PSG4 HUNK RAB11FIP1 OSBPL3 MYO3B CRYBG1	8.80e-06	194	167	7	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HNF1B HIP1R STIL KIF20A FREM2 KIF15 MYO3B	8.80e-06	194	167	7	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HNF1B PSG4 HUNK RAB11FIP1 OSBPL3 MYO3B CRYBG1	8.80e-06	194	167	7	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ZWILCH STIL FANCA KIF20A KIF15 WDHD1 EXO1	9.40e-06	196	167	7	1d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	CHD9 PALMD HUNK FCGBP SECISBP2 ARHGAP21 SEZ6	9.40e-06	196	167	7	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SGK1 SUSD3 ADAM28 FCGBP CSF1R KIF15 EXO1	9.40e-06	196	167	7	b15812354128c12a588d79ef449d787e74835f3b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	CHD9 PALMD HUNK FCGBP SECISBP2 ARHGAP21 SEZ6	9.40e-06	196	167	7	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZWILCH STIL KIF20A KIF15 WDHD1 EXO1 HBB	9.72e-06	197	167	7	21861d8b389fafbdb7c3499684c9b6deee3dbd5e
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZWILCH STIL KIF20A KIF15 WDHD1 EXO1 HBB	9.72e-06	197	167	7	ffb004c37cdd26cb7cdcd80f769a2eded65416dc
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZWILCH STIL KIF20A KIF15 WDHD1 EXO1 HBB	9.72e-06	197	167	7	4b13335a43b9d6abc8e542e72440da7feb82fbe6
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ZWILCH STIL FANCA KIF20A KIF15 WDHD1 EXO1	9.72e-06	197	167	7	8b616cde333bdbc0c591035ad9e4949155866245
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SGK1 MFSD4A CHD9 ADAM28 IVNS1ABP PLEKHH1 NKTR	1.04e-05	199	167	7	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	control-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SGK1 CHD9 ADAM28 IVNS1ABP PLEKHH1 RIF1 NKTR	1.04e-05	199	167	7	3d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell	Biopsy_IPF-Immune-cDCs\|Biopsy_IPF / Sample group, Lineage and Cell type	GLIPR1 SGK1 SUSD3 ADAM28 RFTN1 FCGBP CSF1R	1.07e-05	200	167	7	f7730e2d3ed14a86141491fd20e3aa562670c757
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DCHS2 NBEA HUNK ADAM28 FCGBP PER2 SPDYE16	1.07e-05	200	167	7	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MFSD4A PALMD TJP1 TNK2 NKTR ZNF518B SMAD5	1.07e-05	200	167	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MFSD4A PALMD TJP1 TNK2 NKTR ZNF518B SMAD5	1.07e-05	200	167	7	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LA-06._Ventricular_Cardiomyocyte_II\|LA / Chamber and Cluster_Paper	HNF1B A1CF ZNF230 FDXR HBB	2.51e-05	92	167	5	fad2e02ae858e3a9bbe51ad1c689f7e31d11ce0e
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GLIPR1 HNF1B KIF20A MYO3B C1orf105	2.79e-05	94	167	5	9664f74bc0168c92fb8a68cad628323c476f6103
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GLIPR1 HNF1B KIF20A MYO3B C1orf105	2.79e-05	94	167	5	c73e99890431750b74f984de5c82e33533ab708b
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GLIPR1 HNF1B KIF20A MYO3B C1orf105	2.79e-05	94	167	5	1bda61101f45f5c4a68453087b880fdc6d9acfca
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B HAUS5 PACS1 HSPB6 MDC1 MLH1	2.94e-05	158	167	6	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-2\|TCGA-Lung / Sample_Type by Project: Shred V9	STIL KIF15 WDHD1 KCNC1 MDC1 SEZ6	2.94e-05	158	167	6	9dea15b28f64206bac0e785df6f36a2cc9010ac7
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HAUS5 MFSD4A HUNK MFSD4B ADAM28 TLL2	2.94e-05	158	167	6	41cf950983f47a9e55d56041b301006b42853b37
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|normal_Pleural_Fluid / Location, Cell class and cell subclass	ABCA3 ANK2 EEPD1 FDXR GZMM TNFAIP3	3.05e-05	159	167	6	ebd840ac2b07e62086ee7b5bb01c21804a0fdc7b
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZWILCH STIL FANCA KIF20A KIF15 EXO1	3.27e-05	161	167	6	0dd1401b4c990d49fccb702a9f9867590a58e203
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZWILCH STIL FANCA KIF20A KIF15 EXO1	3.27e-05	161	167	6	b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZWILCH STIL FANCA KIF20A KIF15 EXO1	3.27e-05	161	167	6	efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZWILCH STIL FANCA KIF20A KIF15 EXO1	3.27e-05	161	167	6	28d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SC5D TMEM131L CRYBG1 NKTR TNFAIP3 HBB	3.39e-05	162	167	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SUSD3 CHD9 HEATR5A MFSD4B CSF1R TNFAIP3	3.88e-05	166	167	6	063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SUSD3 CHD9 HEATR5A MFSD4B CSF1R TNFAIP3	3.88e-05	166	167	6	f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCell	LV-11._Adipocyte\|World / Chamber and Cluster_Paper	MAMLD1 LGALS12 EEPD1 GYG2 PRKCQ MAP2K6	3.88e-05	166	167	6	7e5852891714465c6228c9f955fd511ec79d0e02
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SUSD3 CHD9 HEATR5A MFSD4B CSF1R TNFAIP3	3.88e-05	166	167	6	417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLIPR1 ATR RAB11FIP1 MYO3B GZMM TMEM131L	4.15e-05	168	167	6	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STIL FANCA KIF20A KIF15 SKOR2 EXO1	4.29e-05	169	167	6	54b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A IVNS1ABP FCGBP OSBPL3 MYO3B MAP2K6	4.89e-05	173	167	6	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A DSCAML1 PXDNL OSBPL3 MYO3B PRKCQ	5.21e-05	175	167	6	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	STIL KIF20A KIF15 EGR4 EXO1 PRKCQ	5.21e-05	175	167	6	16d4e97271df1db9a0d167fc82a90d84d20dd1f2
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	STIL KIF20A KIF15 EGR4 EXO1 PRKCQ	5.21e-05	175	167	6	553e68e8b439a2293efb969e1e2aa017ceb80daf
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	STIL KIF20A KIF15 EGR4 EXO1 PRKCQ	5.21e-05	175	167	6	289d2aa7164bc02b1876b99f2fb67baa8e030c4e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 MFSD4A PXDNL OSBPL3 MYO3B PRKCQ	5.73e-05	178	167	6	4df6218b20c2f076c22346d23260964cc0d73e65
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD PALMD STIL KIF20A KIF15 SPDYE5	5.73e-05	178	167	6	ea10117026021c959ffc871fc377cdb3e161d264
ToppCell	normal_Lung-Myeloid_cells-CD163+CD14+_DCs\|normal_Lung / Location, Cell class and cell subclass	GLIPR1 SGK1 KDM6B ADAM28 CSF1R TNFAIP3	5.73e-05	178	167	6	b6dacaad09bf4384d0d4c926fbf769e74a8ec9a9
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATR PTPN23 GZMM TNK2 KLK1 MAP2K6	5.73e-05	178	167	6	89f0537459a321ded956bf70ad56fefc0854f8b0
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	DCHS2 MFSD4A NBEA HUNK ADAM28 FCGBP	5.91e-05	179	167	6	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILC2\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GLIPR1 KIF21B LGALS12 GZMM CXorf58 TNFAIP3	5.91e-05	179	167	6	b8bc03f60a7ac76ea6ee90d0512f0dc1d1d2a087
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 MFSD4A PXDNL OSBPL3 MYO3B PRKCQ	6.09e-05	180	167	6	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FANCA KIF20A KIF15 WDHD1 FDXR EXO1	6.09e-05	180	167	6	42f48e646fc6e72ad3cce72409ace3a0b64020a2
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	A1CF CEP76 ZNF230 PLEKHG3 OSBPL3 HBB	6.09e-05	180	167	6	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAUS5 STIL KIF20A WDHD1 KCNC1 EXO1	6.09e-05	180	167	6	87347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell	P15-Endothelial-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	STIL FANCA KIF20A KIF15 WDHD1 EXO1	6.28e-05	181	167	6	0c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCell	P15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	STIL FANCA KIF20A KIF15 WDHD1 EXO1	6.28e-05	181	167	6	f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HNF1B ANK2 HUNK DSCAML1 PXDN PRKCQ	6.28e-05	181	167	6	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	OSBPL3 ARID2 TMEM131L CRYBG1 NKTR TNFAIP3	6.28e-05	181	167	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HNF1B ANK2 HUNK DSCAML1 PXDN PRKCQ	6.48e-05	182	167	6	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	Control-T/NK-proliferating_T/NK\|Control / Disease group,lineage and cell class （2021.01.30）	STIL KIF20A KIF15 EGR4 EXO1 PRKCQ	6.68e-05	183	167	6	e740f05536d1e4b2512811771928eb65f6696409
ToppCell	critical-Epithelial-Ionocyte\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ALKAL1 ANK2 KLK3 TFPI PXDN SC5D	6.88e-05	184	167	6	58d36577eff814d46d72f031f3533d71549e3d6e
ToppCell	Dendritic_Cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	GLIPR1 SGK1 ADAM28 IVNS1ABP CSF1R KIF15	7.30e-05	186	167	6	1d52912bd17e232cf39b2423a4d93585c164ba34
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 MFSD4A PXDNL OSBPL3 MYO3B PRKCQ	7.30e-05	186	167	6	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HNF1B HIP1R FREM2 FCGBP MICAL2 PRKCQ	7.30e-05	186	167	6	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 MFSD4A PXDNL OSBPL3 MYO3B PRKCQ	7.30e-05	186	167	6	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HNF1B HIP1R FREM2 MICAL2 MYO3B PRKCQ	7.52e-05	187	167	6	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPN23 CHD9 CEP76 PLEKHH1 PACS1 MLH1	7.52e-05	187	167	6	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPN23 CHD9 CEP76 PLEKHH1 PACS1 MLH1	7.52e-05	187	167	6	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	LAM-Myeloid-DC\|LAM / Condition, Lineage and Cell class	GLIPR1 SGK1 SUSD3 ADAM28 FCGBP CSF1R	7.75e-05	188	167	6	b4140110c2f7d25fd8a0d2749e33e02003ac4bf2
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	TEX15 KIF20A PLEKHH1 KIF15 EXO1 CCDC116	7.75e-05	188	167	6	723348a1836a074e068320cb736ce6a953e0038f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HNF1B ANK2 HUNK DSCAML1 FCGBP OSBPL3	8.21e-05	190	167	6	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A IVNS1ABP PXDNL OSBPL3 MYO3B PRKCQ	8.21e-05	190	167	6	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	STIL FANCA KIF15 WDHD1 MDC1 EXO1	8.21e-05	190	167	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HNF1B ANK2 HUNK DSCAML1 FCGBP OSBPL3	8.21e-05	190	167	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLIPR1 HUNK KCNC1 OSBPL3 SP5 TMEM131L	8.21e-05	190	167	6	8c9c230a509afaeee50644153974a5642b01a2b8
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ALKAL1 STIL FANCA KIF15 WDHD1 EXO1	8.21e-05	190	167	6	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZWILCH FANCA KIF20A KIF15 WDHD1 EXO1	8.45e-05	191	167	6	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	IVNS1ABP RRP12 TMEM131L CRYBG1 NKTR TNFAIP3	8.70e-05	192	167	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANK2 RAB11FIP1 TFPI MICAL2 PLEKHG3 GNAS	8.70e-05	192	167	6	d43caf42ec744e895137f31ef65a990e250669d2
ToppCell	facs-BAT-Fat-3m-Endothelial-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD SGK1 TNS2 PALMD ABLIM3 TJP1	8.95e-05	193	167	6	e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCell	(1)_T_cells-(1)_T_CD4\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	SGK1 SUSD3 KDM6B SC5D CRYBG1 TNFAIP3	8.95e-05	193	167	6	788daf1d7c7a26eb052b386a114248772e05c27e
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	STIL FANCA KIF15 WDHD1 MDC1 EXO1	8.95e-05	193	167	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	CHD9 STIL RAB11FIP1 KDM6B MFSD4B ADAM28	8.95e-05	193	167	6	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	facs-BAT-Fat-3m-Endothelial-endothelial_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD SGK1 TNS2 PALMD ABLIM3 TJP1	8.95e-05	193	167	6	a211b386fd0fb9da9937361d29d90925a72c9715
ToppCell	facs-BAT-Fat-3m-Endothelial\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD SGK1 TNS2 PALMD ABLIM3 TJP1	8.95e-05	193	167	6	3086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HNF1B ABCA3 RFTN1 FREM2 MICAL2 PRKCQ	9.21e-05	194	167	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HNF1B HIP1R RAB11FIP1 FREM2 MICAL2 SP5	9.21e-05	194	167	6	c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NBEA GIT2 RAB11FIP1 OSBPL3 MYO3B CRYBG1	9.21e-05	194	167	6	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	control-Lymphocytic-Prol._cells\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ZWILCH STIL KIF15 WDHD1 EXO1 SPDYE5	9.21e-05	194	167	6	4c76508de3291c952386caffda2d559629ba5998
Drug	Sulfamethizole [144-82-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A	MIIP GIT1 HAUS5 GIT2 FANCA NEK1 CSF1R WDHD1 GYG2 ZNF701 GNAS	1.76e-07	197	162	11	6099_DN
Drug	nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A	IPPK MBTD1 ABLIM3 NEK1 VPS13D SMG7 WDHD1 MICAL2 TNK2 DLG3 WDTC1	1.86e-07	198	162	11	6983_DN
Drug	Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; HL60; HT_HG-U133A	LRRK1 TEX15 KCNC1 TJP1 MICAL2 HSPB6 C1orf105 NKTR SRRM2 SMAD5	1.48e-06	196	162	10	2331_UP
Drug	PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A	IPPK TNS2 TFPI PACS1 LIG4 VPS13D WDHD1 PLEKHG3 SECISBP2 NKTR	1.62e-06	198	162	10	6907_UP
Drug	Spironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A	HAUS5 GSDMB ZNF230 NEK1 VPS13D SECISBP2 DLG3 NKTR TNFAIP3 GNAS	1.70e-06	199	162	10	5781_DN
Drug	Trazodone hydrochloride [25332-39-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	GLIPR1 MBTD1 HAUS5 PPM1A FANCA MTRR DLG3 NKTR ZNF468 SRRM2	1.77e-06	200	162	10	7410_DN
Drug	Isotretinoin [4759-48-2]; Down 200; 13.4uM; HL60; HT_HG-U133A	GLIPR1 LRRK1 RRP1 TRIM66 RFTN1 MICAL2 OSBPL3 RRP12 SMAD5	7.71e-06	186	162	9	2407_DN
Drug	Nocodazole [31430-18-9]; Up 200; 13.2uM; PC3; HT_HG-U133A	GLIPR1 SGK1 MAMLD1 LRRK1 PACS1 VPS13D SMG7 OSBPL3 TNFAIP3	9.16e-06	190	162	9	7145_UP
Drug	LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A	GLIPR1 SGK1 GIT2 LIG4 SMG7 WDHD1 PLEKHG3 MAP2K6 WDTC1	9.55e-06	191	162	9	6998_DN
Drug	Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A	MIIP ABLIM3 NEK1 VPS13D WDHD1 RRP12 ZNF701 MAP2K6 WDTC1	1.18e-05	196	162	9	6777_DN
Drug	Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; PC3; HT_HG-U133A	MIIP MBTD1 CHD9 LRRK1 PALMD SMG7 WDHD1 EXO1 MAP2K6	1.18e-05	196	162	9	6692_DN
Drug	Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A	GLIPR1 TBL1Y TNS2 PALMD KDM6B ADAM28 PER2 HSPB6 TNK2	1.22e-05	197	162	9	6830_UP
Drug	Bucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; PC3; HT_HG-U133A	HNF1B GIT1 GIT2 VPS13D SMG7 MTRR SRRM2 SMAD5 WDTC1	1.22e-05	197	162	9	5886_DN
Drug	Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; MCF7; HT_HG-U133A	GIT1 SGK1 GIT2 KDM6B PPM1A FANCA TRIM66 NEK1 PLEKHG3	1.22e-05	197	162	9	6237_DN
Drug	Trioxsalen [3902-71-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A	KIF21B TBL1Y HAUS5 ABLIM3 TFPI PACS1 CSF1R HSPB6 GNAS	1.27e-05	198	162	9	6216_UP
Drug	Prednisone [53-03-2]; Up 200; 11.2uM; PC3; HG-U133A	GLIPR1 RIOK3 TFPI VPS13D SMG7 WDHD1 PLEKHG3 RRP12 SECISBP2	1.27e-05	198	162	9	1897_UP
Drug	Betazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A	GIT1 GSDMB TNS2 GIT2 LIG4 PLEKHG3 NKTR SMAD5 WDTC1	1.27e-05	198	162	9	1690_DN
Drug	butadiene diolepoxide	TFPI TKT GNAS	2.88e-05	9	162	3	CID000108199
Drug	Parthenolide [20554-84-1]; Down 200; 16.2uM; PC3; HT_HG-U133A	GIT2 PALMD PPM1A IVNS1ABP PER2 PLEKHG3 TNFAIP3 SMAD5	4.40e-05	179	162	8	5105_DN
Drug	lomustine; Down 200; 100uM; PC3; HT_HG-U133A	HNF1B GIT1 FANCA VPS13D PER2 TNFAIP3 MAP2K6 SMAD5	4.58e-05	180	162	8	7094_DN
Drug	sebacate	ATR INO80 FANCA LIG4 MDC1 MLH1 EXO1 HBB	4.76e-05	181	162	8	CID000005192
Drug	Leu-Dox	KLK3 TFPI KLK1	5.60e-05	11	162	3	CID000068897
Drug	Nocodazole [31430-18-9]; Down 200; 13.2uM; PC3; HT_HG-U133A	JCAD MBTD1 NBEA ABLIM3 NEK1 DLG3 GNAS MAP2K6	6.71e-05	190	162	8	7145_DN
Drug	LY 294002; Up 200; 10uM; PC3; HT_HG-U133A	MBTD1 ABCA3 TEX15 TFPI PACS1 TNK2 NKTR HBB	6.96e-05	191	162	8	1227_UP
Drug	Digitoxigenin [143-62-4]; Down 200; 10.6uM; PC3; HT_HG-U133A	MIIP MBTD1 GIT2 TRIM66 LIG4 VPS13D MAP2K6 SMAD5	6.96e-05	191	162	8	4217_DN
Drug	AC1L4EWU	FDXR MLH1 MTRR	7.42e-05	12	162	3	CID000155754
Drug	7-deoxydoxorubicinone	IVNS1ABP FDXR MTRR	7.42e-05	12	162	3	CID000083958
Drug	mono-(2-ethylhexyl)phthalate	KIF21B SGK1 SUSD3 JAKMIP3 KLK3 PACS1 NEK1 FCGBP PER2 EGR4 TJP1 TLL2 FDXR TNFAIP3 PLD1	7.55e-05	658	162	15	ctd:C016599
Drug	Disulfiram [97-77-8]; Down 200; 13.4uM; HL60; HG-U133A	GLIPR1 ATR HIP1R GIT2 KDM6B RFTN1 RRP12 WDTC1	7.76e-05	194	162	8	1369_DN
Drug	Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A	MIIP PDK2 HAUS5 TNS2 VPS13D CSF1R PLEKHG3 RRP12	7.76e-05	194	162	8	6779_DN
Drug	5279552; Up 200; 22uM; MCF7; HT_HG-U133A_EA	HNF1B PDK2 GSDMB GIT2 TRIM66 PACS1 RFTN1 LIG4	7.76e-05	194	162	8	843_UP
Drug	Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; HL60; HT_HG-U133A	A1CF TNS2 LRRK1 TEX15 PER2 MICAL2 SRRM2 SMAD5	7.76e-05	194	162	8	6160_DN
Drug	Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A	GIT2 TRIM66 PACS1 VPS13D EGR4 GYG2 SMAD5 WDTC1	8.04e-05	195	162	8	3454_UP
Drug	Clioquinol [130-26-7]; Down 200; 13uM; HL60; HT_HG-U133A	MIIP MBTD1 A1CF HAUS5 HIP1R TSC22D4 MAP2K6 WDTC1	8.04e-05	195	162	8	3084_DN
Drug	Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; HL60; HT_HG-U133A	MIIP TNS2 LRRK1 SMG7 TNK2 PLD1 TSC22D4 SMAD5	8.33e-05	196	162	8	1849_UP
Drug	Lactobionic acid [96-82-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	MIIP MBTD1 PDK2 TFPI FANCA VPS13D TNK2 PLD1	8.33e-05	196	162	8	6605_DN
Drug	Dosulepin hydrochloride [897-15-4]; Up 200; 12uM; HL60; HG-U133A	GIT2 FANCA VPS13D CSF1R SMG7 OSBPL3 ECI2 SMAD5	8.33e-05	196	162	8	1713_UP
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A	MIIP GLIPR1 VPS13D CSF1R SMG7 NKTR SMAD5 WDTC1	8.33e-05	196	162	8	4728_DN
Drug	Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A	MIIP GIT2 LIG4 MICAL2 RRP12 SECISBP2 ZNF468 TSC22D4	8.33e-05	196	162	8	7200_UP
Drug	Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; PC3; HT_HG-U133A	JCAD ABCA3 HIP1R GIT2 LRRK1 CSF1R NKTR HBB	8.33e-05	196	162	8	2101_UP
Drug	Isocarboxazid [59-63-2]; Down 200; 17.2uM; PC3; HT_HG-U133A	JCAD EPPK1 GSDMB PACS1 SECISBP2 TNK2 DLG3 TSC22D4	8.64e-05	197	162	8	7383_DN
Drug	Quipazine dimaleate salt [4774-24-7]; Down 200; 9uM; PC3; HT_HG-U133A	HAUS5 GIT2 PALMD ZNF230 FANCA VPS13D SRRM2 SMAD5	8.64e-05	197	162	8	5887_DN
Drug	Meticrane [1084-65-7]; Down 200; 14.6uM; PC3; HT_HG-U133A	PALMD ZNF230 RAB11FIP1 TRIM66 SMG7 DLG3 SRRM2 SMAD5	8.64e-05	197	162	8	7282_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	PDK2 GIT2 KDM6B ABLIM3 NEK1 SMG7 PLEKHG3 RRP12	8.64e-05	197	162	8	1496_DN
Drug	Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; PC3; HT_HG-U133A	MIIP GIT2 KDM6B PPM1A NEK1 DLG3 TSC22D4 SMAD5	8.64e-05	197	162	8	1799_DN
Drug	Netilmicin sulfate [56931-57-2]; Up 200; 2.8uM; MCF7; HT_HG-U133A	PDK2 ZNF235 TFPI CSF1R PER2 HSPB6 TNK2 GNAS	8.64e-05	197	162	8	3524_UP
Drug	Antigens, Polyomavirus Transforming	MBTD1 RNF168 ARRDC1 HAUS5 CEP76 FANCA RIF1 ARID2 EXO1 NKTR ZNF518B TNFAIP3 PLD1 USP47 WDTC1	8.93e-05	668	162	15	ctd:D000952
Drug	Chlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; HL60; HT_HG-U133A	KDM6B KIF20A VPS13D SMG7 WDHD1 MAP2K6 SMAD5 WDTC1	8.95e-05	198	162	8	1272_DN
Drug	Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	A1CF GIT1 GIT2 ZNF230 TRIM66 CSF1R DLG3 SRRM2	8.95e-05	198	162	8	5786_DN
Drug	Evoxine [522-11-2]; Down 200; 11.6uM; PC3; HT_HG-U133A	JCAD LRRK1 ZNF230 KDM6B SMG7 TNFAIP3 SRRM2 WDTC1	8.95e-05	198	162	8	3681_DN
Drug	Norfloxacin [70458-96-7]; Up 200; 12.6uM; PC3; HT_HG-U133A	JCAD GIT1 LRRK1 VPS13D DTWD1 PLEKHG3 TSC22D4 SMAD5	8.95e-05	198	162	8	2090_UP
Drug	Evoxine [522-11-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	MBTD1 PDK2 KDM6B TFPI RFTN1 LIG4 PLEKHG3 SMAD5	8.95e-05	198	162	8	6041_DN
Drug	Chlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A	MBTD1 PDK2 PPM1A PACS1 NEK1 CSF1R WDHD1 WDTC1	8.95e-05	198	162	8	2217_DN
Drug	Nitrocaramiphen hydrochloride; Down 200; 10.8uM; MCF7; HT_HG-U133A	GLIPR1 ABCA3 HAUS5 RIOK3 IVNS1ABP RFTN1 WDHD1 SMAD5	8.95e-05	198	162	8	7464_DN
Drug	STOCK1N-35696; Down 200; 15uM; PC3; HT_HG-U133A	FLNA PDK2 NEK1 TKT SECISBP2 ZNF701 NKTR MAP2K6	8.95e-05	198	162	8	6564_DN
Drug	Tadjakonine [11087-94-8]; Down 200; 7.4uM; HL60; HT_HG-U133A	MIIP GLIPR1 A1CF GIT1 HIP1R FDXR TSC22D4 SRRM2	9.26e-05	199	162	8	2165_DN
Drug	Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	GLIPR1 HIP1R KDM6B NEK1 WDHD1 TJP1 PLEKHG3 SMAD5	9.26e-05	199	162	8	6219_DN
Drug	Mafenide hydrochloride [138-37-4]; Up 200; 18uM; MCF7; HT_HG-U133A	GLIPR1 TEX15 PACS1 PER2 HSPB6 TNFAIP3 PLD1 HBB	9.26e-05	199	162	8	2287_UP
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	MIIP PDK2 SGK1 TFPI PACS1 RRP12 NKTR SMAD5	9.26e-05	199	162	8	1484_DN
Drug	Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; PC3; HT_HG-U133A	JCAD TNS2 PALMD ZNF230 DTWD1 DLG3 SRRM2 WDTC1	9.26e-05	199	162	8	7254_DN
Drug	Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A	GLIPR1 A1CF TBL1Y ZNF235 ADAM28 OSBPL3 PLD1 TSC22D4	9.26e-05	199	162	8	5423_UP
Drug	Bumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A	GLIPR1 MBTD1 EPPK1 SGK1 GIT2 SMG7 DLG3 ECI2	9.26e-05	199	162	8	5542_DN
Drug	Estriol [50-27-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A	FLNA GSDMB GIT2 TRIM66 NEK1 PLEKHG3 C1orf105 GYG2	9.26e-05	199	162	8	3563_DN
Drug	Probucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A	KIF21B TBL1Y HIP1R RIF1 VPS13D PER2 PLEKHG3 NKTR	9.59e-05	200	162	8	5626_UP
Drug	Acetaminophen [103-90-2]; Down 200; 26.4uM; PC3; HT_HG-U133A	ABCA3 PDK2 PALMD FANCA VPS13D PLEKHG3 MTRR GNAS	9.59e-05	200	162	8	6284_DN
Drug	celecoxib; Up 200; 10uM; MCF7; HG-U133A	GIT2 KDM6B VPS13D SMG7 MICAL2 RRP12 MTRR TNK2	9.59e-05	200	162	8	377_UP
Drug	Laudanosine (R,S) [1699-51-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A	MIIP GIT1 GIT2 VPS13D WDHD1 PLEKHG3 GYG2 DLG3	9.59e-05	200	162	8	7030_UP
Drug	Acenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A	MIIP HNF1B MAMLD1 GIT2 ZNF230 PACS1 DLG3 TSC22D4	9.59e-05	200	162	8	2077_UP
Drug	Azacyclonol [115-46-8]; Down 200; 15uM; PC3; HT_HG-U133A	MIIP HAUS5 GSDMB PALMD PACS1 OSBPL3 MTRR MAP2K6	9.59e-05	200	162	8	6298_DN
Drug	Artemisinin [63968-64-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A	GIT1 PDK2 TNS2 FANCA CSF1R GZMM NKTR MAP2K6	9.59e-05	200	162	8	7007_UP
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	MBTD1 HAUS5 GSDMB GIT2 KDM6B NEK1 SMG7 SMAD5	9.59e-05	200	162	8	3577_DN
Drug	Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A	HNF1B HIP1R LRRK1 TEX15 ZNF230 KCNC1 MICAL2 PLEKHG3	9.59e-05	200	162	8	3619_UP
Drug	fullerol C60(OH)24	PDK2 SGK1 PER2	9.60e-05	13	162	3	ctd:C408042
Drug	S-7HNa	PPIG TKT HBB	1.22e-04	14	162	3	CID000188208
Drug	azotomycin	IL17C MLH1	1.50e-04	3	162	2	CID000024281
Drug	phenyl hypoiodite	PPIG FDXR MTRR	2.23e-04	17	162	3	CID000555748
Drug	methyl methanesulfonate	INO80 RRP1 TFPI FANCA LIG4 MDC1 MLH1 EXO1 PRKCQ HBB	2.91e-04	364	162	10	CID000004156
Drug	diiodofluorescein	FDXR MTRR	2.99e-04	4	162	2	CID000092311
Drug	15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A	HNF1B PALMD KIF20A TRIM66 VPS13D KIF15 NKTR	3.34e-04	182	162	7	1231_DN
Drug	BE 51	TFPI FDXR MTRR	3.69e-04	20	162	3	CID000061972
Drug	Ethotoin [86-35-1]; Down 200; 19.6uM; PC3; HT_HG-U133A	ZWILCH MBTD1 RIOK3 ZNF230 NEK1 NKTR GNAS	4.07e-04	188	162	7	4545_DN
Drug	Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; PC3; HT_HG-U133A	KDM6B FANCA NEK1 SMG7 TNFAIP3 SRRM2 SMAD5	4.20e-04	189	162	7	6649_DN
Drug	Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A	IPPK SGK1 RRP1 FANCA DTWD1 WDHD1 DLG3	4.33e-04	190	162	7	7405_DN
Drug	colcemid; Up 200; 11.7uM; MCF7; HT_HG-U133A_EA	FLNA ABCA3 EPPK1 HIP1R RIOK3 KDM6B TMEM131L	4.33e-04	190	162	7	1103_UP
Drug	Triflupromazine hydrochloride [1098-60-8]; Up 200; 10.2uM; PC3; HT_HG-U133A	MBTD1 TNS2 LRRK1 KDM6B TFPI TNFAIP3 WDTC1	4.47e-04	191	162	7	1813_UP
Drug	thioridazine hydrochloride; Down 200; 10uM; PC3; HT_HG-U133A	A1CF GIT1 PALMD FANCA VPS13D SRRM2 MAP2K6	4.47e-04	191	162	7	4454_DN
Drug	Bupivacaine hydrochloride [18010-40-7]; Down 200; 12.4uM; MCF7; HT_HG-U133A	GLIPR1 EPPK1 VPS13D SMG7 TSC22D4 SRRM2 SMAD5	4.47e-04	191	162	7	7435_DN
Drug	vinblastine sulfate; Up 200; 0.1uM; PC3; HT_HG-U133A	GLIPR1 JCAD HNF1B PDK2 PACS1 TNK2 TNFAIP3	4.61e-04	192	162	7	7556_UP
Drug	Homatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; PC3; HT_HG-U133A	RIOK3 FANCA LIG4 NEK1 PLEKHG3 DLG3 SMAD5	4.61e-04	192	162	7	5058_DN
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	MAMLD1 HIP1R TEX15 ZNF235 GYG2 ECI2 PLD1	4.61e-04	192	162	7	2450_UP
Drug	AC1L9GAJ	ANK2 KLK3 TKT PLD1	4.76e-04	51	162	4	CID000444421
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A	MIIP HAUS5 VPS13D SMG7 GYG2 DLG3 WDTC1	4.76e-04	193	162	7	3412_DN
Drug	Etofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A	HNF1B GIT1 LRRK1 TRIM66 PACS1 SMAD5 WDTC1	4.76e-04	193	162	7	2093_UP
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A	MBTD1 LIG4 CSF1R KCNC1 EGR4 GYG2 PLD1	4.76e-04	193	162	7	7238_UP
Drug	Bromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A	GLIPR1 GIT2 PACS1 VPS13D WDHD1 PLEKHG3 SMAD5	4.91e-04	194	162	7	5665_DN
Drug	Prednicarbate [73771-04-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A	GSDMB GIT2 RFTN1 NEK1 DLG3 ZNF701 SMAD5	4.91e-04	194	162	7	5544_DN
Drug	PHA-00846566E [724718-26-7]; Up 200; 10uM; PC3; HT_HG-U133A	JCAD MBTD1 CEP76 GIT2 FANCA WDHD1 RRP12	4.91e-04	194	162	7	7086_UP
Drug	Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; PC3; HT_HG-U133A	GSDMB RIOK3 GIT2 TFPI LIG4 TNFAIP3 TSC22D4	4.91e-04	194	162	7	5075_DN
Drug	Hycanthone [3105-97-3]; Up 200; 11.2uM; HL60; HG-U133A	ATR GIT1 SGK1 FANCA PPIG DTWD1 WDHD1	4.91e-04	194	162	7	1614_UP
Drug	PHA-00745360 [351320-33-7]; Down 200; 10uM; PC3; HT_HG-U133A	A1CF GSDMB LRRK1 TRIM66 RRP12 DLG3 TSC22D4	4.91e-04	194	162	7	4559_DN
Disease	systemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus	RSBN1 SMG7 TNFAIP3 CCDC116	5.32e-05	38	160	4	EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Disease	sensory system disease (implicated_via_orthology)	TBL1Y TBL1XR1	8.73e-05	3	160	2	DOID:0050155 (implicated_via_orthology)
Disease	trait in response to apixaban	NMUR2 ABLIM3 MYO3B GNAS ABLIM2	4.18e-04	115	160	5	OBA_2050328
Disease	restrictive cardiomyopathy (is_implicated_in)	KIF20A MAP2K6	4.32e-04	6	160	2	DOID:397 (is_implicated_in)
Disease	Polydactyly	MKKS SALL4 FREM2 NEK1 SC5D	4.53e-04	117	160	5	C0152427
Disease	lung cancer (is_implicated_in)	ATR CSF1R MLH1 CCDC116	7.13e-04	74	160	4	DOID:1324 (is_implicated_in)
Disease	Hypoxemia	TFPI TKT GNAS	7.58e-04	33	160	3	C0700292
Disease	Hypoxia	TFPI TKT GNAS	7.58e-04	33	160	3	C0242184
Disease	Anoxemia	TFPI TKT GNAS	7.58e-04	33	160	3	C0003129
Disease	Anoxia	TFPI TKT GNAS	7.58e-04	33	160	3	C0003130
Disease	optic disc size measurement	NMUR2 PPM1A RFTN1 PLEKHG3 MAP2K6 ARHGAP21	9.13e-04	205	160	6	EFO_0004832
Disease	Lymphoma	LIG4 MLH1 TNFAIP3	1.33e-03	40	160	3	C0024299
Disease	autism spectrum disorder (implicated_via_orthology)	ABCA3 CHD9 NBEA DSCAML1 CNTNAP4	1.47e-03	152	160	5	DOID:0060041 (implicated_via_orthology)
Disease	reticulocyte measurement	FLNA KREMEN1 ATR RIOK3 IP6K1 KDM6B PACS1 MICAL2 EEPD1 C1orf105 TMEM131L PLD1 ARHGAP21 HOMEZ	1.84e-03	1053	160	14	EFO_0010700
Disease	Prostatic Neoplasms	HNF1B ATR KLK3 TBL1XR1 ADAM28 IVNS1ABP ARID2 MLH1 SP5 SDF2L1	2.03e-03	616	160	10	C0033578
Disease	Malignant neoplasm of prostate	HNF1B ATR KLK3 TBL1XR1 ADAM28 IVNS1ABP ARID2 MLH1 SP5 SDF2L1	2.03e-03	616	160	10	C0376358
Disease	ocular hypertension, response to triamcinolone acetonide	RIOK3 CHD9 PALMD	2.40e-03	49	160	3	EFO_0006954, EFO_1001069
Disease	QT interval	MBTD1 GIT2 PXDN SC5D ARID2 TMEM131L TSC22D4 NEURL4 ARHGAP21	2.64e-03	534	160	9	EFO_0004682
Disease	platelet component distribution width	JCAD KREMEN1 MAMLD1 ZNF490 PLEKHG3 C1orf105 MLH1 TMEM131L DLG3 GNAS TSC22D4	2.84e-03	755	160	11	EFO_0007984
Disease	total blood protein measurement	HNF1B A1CF RNF168 RIOK3 LRRK1 CSF1R PKD1 TMEM131L	3.23e-03	449	160	8	EFO_0004536
Disease	pancreatic cancer (is_implicated_in)	ATR FANCA LIG4 MTRR	3.28e-03	112	160	4	DOID:1793 (is_implicated_in)
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	NEK1 PKD1	3.34e-03	16	160	2	DOID:0110861 (implicated_via_orthology)
Disease	Withdrawal Symptoms	PER2 GNAS SMAD5	3.88e-03	58	160	3	C0087169
Disease	Drug Withdrawal Symptoms	PER2 GNAS SMAD5	3.88e-03	58	160	3	C0086189
Disease	Substance Withdrawal Syndrome	PER2 GNAS SMAD5	3.88e-03	58	160	3	C0038587
Disease	Malignant neoplasm of endometrium	ATR MLH1	4.22e-03	18	160	2	C0007103
Disease	Carcinoma in situ of endometrium	ATR MLH1	4.22e-03	18	160	2	C0346191
Disease	colorectal cancer (is_implicated_in)	LIG4 ARID2 MLH1 TNFAIP3	4.33e-03	121	160	4	DOID:9256 (is_implicated_in)
Disease	Chronic myeloproliferative disorder	ATR LIG4	4.70e-03	19	160	2	C1292778
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	MLH1 EXO1	4.70e-03	19	160	2	C1333991
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	GSDMB RSBN1 TNFAIP3	4.90e-03	63	160	3	EFO_0000685, EFO_0007791, EFO_0009459
Disease	Colorectal Carcinoma	ABCA3 ANK2 DSCAML1 DACT1 CFAP77 MLH1 EXO1 MTRR DLG3 GNAS	5.11e-03	702	160	10	C0009402
Disease	carcinoma (implicated_via_orthology)	SALL4 CSF1R DLG3	5.12e-03	64	160	3	DOID:305 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
HPRGFPELSHKSTAA	GNAS	176	P84996
AKHPFPEQSLLIHSG	C21orf62	131	Q9NYP8
QAPKHFHIPAGDSNI	ABLIM3	426	O94929
HPQPFGHFLDFLTES	CCDC116	66	Q8IYX3
PHFQKVGRHLDTFPT	CFAP77	276	Q6ZQR2
PPFIVFKIFLHTDGH	CXorf58	111	Q96LI9
IPSLHFPATKGHLSN	A1CF	356	Q9NQ94
ASFHKDTNALPPTVF	ADAM28	746	Q9UKQ2
TGPVTFSPECSKHFH	ALKAL1	81	Q6UXT8
PSFCHHFSTQEKTPQ	FDXR	26	P22570
PKEITISGSFQGFHH	GSDMB	101	Q8TAX9
SPGLTFHIKAAIQHP	GZMM	86	P51124
FHHSRGSPFKKIPAV	ARID2	26	Q68CP9
PAPGKSVSFPHRNFH	CNTNAP4	316	Q9C0A0
AAVVFEHPFNHSKEP	ABCA3	131	Q99758
EALSFGQENPFPHSH	AKAP11	1056	Q9UKA4
FFHPEKGTTPLHVAA	GIT1	161	Q9Y2X7
FFHPEKGNTPLHVAS	GIT2	161	Q14161
APRHFHVPDTGVKDN	ABLIM2	416	Q6H8Q1
AVPDGHTFKGFPIHF	CEP76	586	Q8TAP6
HTNGGLTFTAKPHPS	EEPD1	206	Q7L9B9
PHFLDPVFLSTKSHS	ARRDC1	326	Q8N5I2
SGKRLEAEFPPHHSQ	TNK2	81	Q07912
EAEFPPHHSQSTFRK	TNK2	86	Q07912
RSHSPPKAFHAGKLF	ANO8	1041	Q9HCE9
GFSLAALHPFVQPTH	RFTN1	76	Q14699
SELAHHLKPFFFPSN	IPPK	231	Q9H8X2
AGAKQPIPAQHHFSS	PTPN23	926	Q9H3S7
HQTKVFAKFSHDAPP	INO80	246	Q9ULG1
PLTKSGQHHIFSFFA	ANK2	1391	Q01484
ESLGSPVHHSPFDAQ	PALMD	511	Q9NP74
GSKHFFHLIPNEATI	MKKS	356	Q9NPJ1
HVKCHEFTATFFPQP	PRKCQ	156	Q04759
PHKLHPNFTSLGENI	GLIPR1	86	P48060
PGHFSVLLDVKHFSP	HSPB6	71	O14558
IFSGAHGPEKDFPLH	MDC1	36	Q14676
LHSNPEPKTFTFDHV	KIF15	61	Q9NS87
TAQFVHVSESFPHPG	KLK1	86	P06870
HVSESFPHPGFNMSL	KLK1	91	P06870
DKFNPHTSPHGISSI	NEDD1	26	Q8NHV4
LFSLPNTSIHGIKFH	NMUR2	176	Q9GZQ4
ESFAFRSHSHLPPKN	NEK1	1011	Q96PY6
DGHFDTPPHLFAKVK	MBTD1	361	Q05BQ5
SSLPPKFQSHLGHED	MFSD4A	276	Q8N468
FNSDSDPHGISHVKF	IVNS1ABP	61	Q9Y6Y0
ISSNKLSHLPPGFLH	LRRK1	336	Q38SD2
SPTATFEKHGEHLPR	GPBP1L1	21	Q9HC44
QTHTAFPTGDHKQRP	JCAD	731	Q9P266
ASSSLFHPGKLHFVF	MTRR	456	Q9UBK8
KTEAQFHGLFVLSHP	FREM2	2746	Q5SZK8
SAPDPKNHHIIKFGT	KDM6B	1316	O15054
DSVHFKPDSVHFKPA	GPR50	456	Q13585
LAPHDVGVFHSFTSP	PER2	231	O15055
DIAFHFNPRFHTTKP	LGALS12	91	Q96DT0
PLFHAKHQNTPSIGL	CSNKA2IP	91	A0A1B0GTH6
KINHFLGDHPAPTVN	KIF21B	876	O75037
KSPAISFHHTPFVDG	JAKMIP3	621	Q5VZ66
SFHHTPFVDGKSPLQ	JAKMIP3	626	Q5VZ66
VPGASHIHFSFPLFD	KREMEN1	246	Q96MU8
PTPGAFAFHTEFIHV	IL17C	171	Q9P0M4
SGSFFIQAVPEHPHD	EGR4	186	Q05215
QAKRGSLPTPHDDHF	HAUS5	206	O94927
KPSLFQHVGIHSSFP	MGAT4D	351	A6NG13
SPFNTGSAHVKHLPE	MFSD4B	496	Q5TF39
PTHVKHFPVGLFSGS	PACS1	946	Q6VY07
FDGSTNPAHPKHIGS	PDK2	176	Q15119
IFFPSEGSNLTPAHH	PIPSL	66	A2A3N6
HNPTFISFPNAHVKE	DCHS2	1616	Q6V1P9
GSQFFITTKPTPHLD	PPIG	121	Q13427
NSGVFVFQPSLHTHK	GYG2	166	O15488
EGHLPFHKALFSPSR	PXDNL	1076	A1KZ92
EHSIKPLFQHSPGDS	ATR	1861	Q13535
FGSPAEHVLSPHSQF	CHD9	86	Q3L8U1
ISAGAHTHPPDEFLF	CSF1R	501	P07333
ISFHLKHPQFPAGLE	HIP1R	141	O75146
FFSHILSLASPSHPK	HEATR5A	326	Q86XA9
PSASEHTHFKNIPIG	KCNC1	376	P48547
VTAPDLHNHPAKTFV	DACT1	796	Q9NYF0
PTEGSLTPFIHNAFK	LIG4	306	P49917
HVSKFDSFHENTRPP	COL20A1	1206	Q9P218
GREPSFSKDQHLFTH	DSCAML1	1476	Q8TD84
TTCHAHVPPESFFKG	FCGBP	3091	Q9Y6R7
ADTHIPGSPFKAHVV	FLNA	1141	P21333
QLGFKSTPPAHSSVF	PIK3CD-AS1	121	Q5SR53
VPLGHTPSQEHFLFE	FANCA	1036	O15360
VKGHFGPINSVAFHP	EIF3I	281	Q13347
HPTLVSFAHEDKNSP	HUNK	616	P57058
DPPTHHFELKTFQTV	CC2D1B	676	Q5T0F9
FSSLSNEIPKEHPGH	AKNAD1	506	Q5T1N1
SEFPHKFGSCVPHTT	DLG3	646	Q92796
PFTFGNTKPLSHFVS	MAMLD1	536	Q13495
AHSTFKGFRDDPTVH	IP6K1	401	Q92551
ATFHTPFSHLGQSPE	ECI2	266	O75521
AHHFGKEFTPPVQAA	HBB	116	P68871
KSLLSFTHHAGRPPE	HOMEZ	136	Q8IX15
EHNPFSQPVHKGNTA	CRYBG1	256	Q9Y4K1
GHFTFTLHLETPKPS	PSG4	136	Q00888
SATDGVPKHQFPHFL	SALL4	1031	Q9UJQ4
FPGPQSISIKDISFH	DTWD1	141	Q8N5C7
KSFPLHSPVAGVAHR	NEURL4	901	Q96JN8
KSPSGFHFHPSHLRT	MICAL2	931	O94851
GFQFFSEQVSHHPPI	OSBPL3	621	Q9H4L5
FTTHSFPTPGLHLVT	PKD1	1766	P98161
HPFFTLHESKGTDVA	MAP2K6	311	P52564
PDTKPVFHTLTNGHA	HNF1B	56	P35680
FTFSPLTVSAAGPKH	RSBN1	171	Q5VWQ0
APSEQTTEFGIHKPH	RAB11FIP1	1041	Q6WKZ4
KHFNKPVSGPSQAHD	SUSD3	166	Q96L08
PQKTHLQPSFGAAHE	SP5	96	Q6BEB4
GGPHFSPEHKELSNS	SRRM2	1306	Q9UQ35
VNSVFAAAGHFHVPP	TMEM131L	126	A2VDJ0
HDASLVHKSPDPFGA	TSC22D4	271	Q9Y3Q8
SQFFITTKPAPHLDG	NKTR	121	P30414
KPHFKLFHPSSESEQ	PLD1	601	Q13393
SPFNSRAAAGPAHHK	PLEKHG3	76	A1L390
EHPLISSPSFFSKHA	RIF1	461	Q5UIP0
SPKENASIFVHSPHA	NBEA	461	Q8NFP9
GPSSNPHAKPSDFHF	SGK1	86	O00141
PHAKPSDFHFLKVIG	SGK1	91	O00141
ASNSQFIPIHHPGAF	SMG7	641	Q92540
HHDPFSGSQIPLFQA	EPPK1	366	P58107
AQHQKLSGTSSPFHP	MIIP	346	Q5JXC2
ASHLAPNHTTFPKIH	SECISBP2	611	Q96T21
HPSSQAPNGVKSHFI	RRP1	156	P56182
SHILPPKHFTEDGNI	MLH1	726	P40692
PEHHKDFNSQLAPGV	SPDYE2B	116	A6NHP3
NHIPGDHIPDKATVF	EXO1	566	Q9UQ84
HTGEAKQQFPFHSAP	TBL1XR1	296	Q9BZK7
FEKAPAHHPAAISTA	RRP12	271	Q5JTH9
NFHHGFHPTTVCKIP	SMAD5	361	Q99717
SLHQPKFQTTPEPFH	C1orf105	116	O95561
PLKFPVQENASHLHG	C12orf4	31	Q9NQ89
QSVEPTHPHGLEFLF	RIOK3	426	O14730
SIKPSSHNGPSHDIF	STIL	521	Q15468
HTGHTANIFSVKFLP	WDTC1	86	Q8N5D0
SSPIDHLNFHKPDFS	ZWILCH	551	Q9H900
QPFLTHERTHTGEKP	ZNF490	291	Q9ULM2
PHNDRFVLSKGHAAP	TKT	66	P29401
PEDIFKPTNGIIHHF	TNFAIP3	26	P21580
HFFPKDKQPSGSHPI	SPEM3	61	A0A1B0GUW6
TGKNLHTHHFPSPLS	SDF2L1	111	Q9HCN8
KVHFFTQDHKPSNPL	PPM1A	156	P35813
GFPSLHSFIKEHSLQ	KIF20A	516	O95235
PEHHKDFNSQLAPGV	SPDYE16	76	A6NNV3
PEHHKDFNSQLAPGV	SPDYE18	116	P0DV79
PEHHKDFNSQLAPGV	SPDYE21	116	A0A494C086
PEHHKDFNSQLAPGV	SPDYE2	116	Q495Y8
VSPILPEHHKGFNSQ	SPDYE5	111	A6NIY4
PEHHKDFNSQLAPGV	SPDYE6	116	P0CI01
KPFQSGSTPLHLTHR	WDHD1	431	O75717
IAQDHLPLHKAFFSP	PXDN	1091	Q92626
KQHLEPFVGVLSSHF	USP47	1066	Q96K76
HSPGTLHAAAKTFSP	TLL2	131	Q9Y6L7
PEKQLHPAGATIHFS	SEZ6	851	Q53EL9
HTGEAKQQFPFHSAP	TBL1Y	306	Q9BQ87
QSTKVPSLFEFHGPS	TFPI	201	P10646
FHHSLPFSIPVHFTN	PLEKHH1	991	Q9ULM0
DGNFKRQTHTKHPTP	RNF168	496	Q8IYW5
FSPNKFIFHSHRTPD	SKOR2	181	Q2VWA4
VSNVGKPSHLPHTFK	ZNF844	506	Q08AG5
SFENKPPAHIAASHL	TJP1	1366	Q07157
DPPQQFHSGEKSHTC	ZNF230	156	Q9UIE0
PEHHKDFNSQLAPGV	nan	76	A6NJR5
PIKNELGSSFHSHLP	ZNF701	201	Q9NV72
HGTFSPDHGTLLQKF	TEX15	2466	Q9BXT5
TPFASHAFHPIDGFL	SC5D	161	O75845
PVAQQEALSHPSHKF	TRIM66	296	O15016
EALSHPSHKFQSPAV	TRIM66	301	O15016
PHKLSETPGSKAEFH	ARHGAP21	1941	Q5T5U3
IEGKSSQFPKHHDSP	ZNF235	126	Q14590
GSSFHLHLPEPHIFQ	ZNF468	141	Q5VIY5
FHTCTIHGPQLTFPK	TNS2	386	Q63HR2
PHRTAFPSVALKGHS	ZNF518B	471	Q9C0D4
VAKHPAGSFHFTAEI	ZNF736	71	B4DX44
HLRFEDGVTNPSHPF	VPS13D	156	Q5THJ4
TGQVFQVSHSFPHPL	KLK3	86	P07288
FHSNPGSTHTTLFPD	MUC12	1081	Q9UKN1
HGVKRASNPPHIFAS	MYO3B	401	Q8WXR4