Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	potassium:proton antiporter activity	SLC9A8 SLC9A2 SLC9A5	2.18e-05	14	80	3	GO:0015386
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9A8 SLC9A2 SLC9A5	3.34e-05	16	80	3	GO:0015385
GeneOntologyMolecularFunction	L-serine ammonia-lyase activity	SRR SDS	4.74e-05	3	80	2	GO:0003941
GeneOntologyMolecularFunction	solute:potassium antiporter activity	SLC9A8 SLC9A2 SLC9A5	5.73e-05	19	80	3	GO:0022821
GeneOntologyMolecularFunction	ammonia-lyase activity	SRR SDS	1.57e-04	5	80	2	GO:0016841
GeneOntologyMolecularFunction	metal cation:proton antiporter activity	SLC9A8 SLC9A2 SLC9A5	1.69e-04	27	80	3	GO:0051139
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC9A8 SLC9A2 SLC9A5 SCN7A ATP1A4	6.22e-04	171	80	5	GO:0015081
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	SLC9A8 SLC9A2 SLC9A5	6.81e-04	43	80	3	GO:0140828
Domain	NaH_exchanger	SLC9A8 SLC9A2 SLC9A5	6.24e-06	9	80	3	IPR004709
Domain	Cadherin	CLSTN3 CELSR2 PCDHB11 DCHS1 FREM1 CDH17	1.15e-05	118	80	6	IPR002126
Domain	Cation/H_exchanger_CPA1	SLC9A8 SLC9A2 SLC9A5	1.22e-05	11	80	3	IPR018422
Domain	Na_H_Exchanger	SLC9A8 SLC9A2 SLC9A5	2.66e-05	14	80	3	PF00999
Domain	Cation/H_exchanger	SLC9A8 SLC9A2 SLC9A5	2.66e-05	14	80	3	IPR006153
Domain	Ser/Thr_deHydtase_PyrdxlP-BS	SRR SDS	5.42e-05	3	80	2	IPR000634
Domain	DEHYDRATASE_SER_THR	SRR SDS	5.42e-05	3	80	2	PS00165
Domain	CADHERIN_1	CLSTN3 CELSR2 PCDHB11 DCHS1 CDH17	1.24e-04	113	80	5	PS00232
Domain	Cadherin	CLSTN3 CELSR2 PCDHB11 DCHS1 CDH17	1.24e-04	113	80	5	PF00028
Domain	CADHERIN_2	CLSTN3 CELSR2 PCDHB11 DCHS1 CDH17	1.30e-04	114	80	5	PS50268
Domain	-	CLSTN3 CELSR2 PCDHB11 DCHS1 CDH17	1.30e-04	114	80	5	2.60.40.60
Domain	CA	CLSTN3 CELSR2 PCDHB11 DCHS1 CDH17	1.35e-04	115	80	5	SM00112
Domain	Cadherin-like	CLSTN3 CELSR2 PCDHB11 DCHS1 CDH17	1.41e-04	116	80	5	IPR015919
Domain	TrpB-like_PLP-dep	SRR SDS	3.75e-04	7	80	2	IPR001926
Domain	PALP	SRR SDS	3.75e-04	7	80	2	PF00291
Domain	EGF	CELSR2 CNTNAP1 BRINP2 LRP6 NID1 VWDE	5.15e-04	235	80	6	SM00181
Domain	Cadherin_CS	CELSR2 PCDHB11 DCHS1 CDH17	1.23e-03	109	80	4	IPR020894
Domain	Ldl_recept_b	LRP6 NID1	1.59e-03	14	80	2	PF00058
Domain	LDLRB	LRP6 NID1	1.59e-03	14	80	2	PS51120
Domain	LY	LRP6 NID1	1.83e-03	15	80	2	SM00135
Domain	LDLR_classB_rpt	LRP6 NID1	1.83e-03	15	80	2	IPR000033
Domain	EGF	CELSR2 CNTNAP1 LRP6 NID1	2.10e-03	126	80	4	PF00008
Domain	EGF_3	CELSR2 CNTNAP1 LRP6 NID1 VWDE	3.38e-03	235	80	5	PS50026
Domain	EGF-like_dom	CELSR2 CNTNAP1 LRP6 NID1 VWDE	4.32e-03	249	80	5	IPR000742
Domain	HAD-like_dom	HDHD5 CTDSP1 ATP1A4	4.74e-03	79	80	3	IPR023214
Domain	EGF_1	CELSR2 CNTNAP1 LRP6 NID1 VWDE	4.77e-03	255	80	5	PS00022
Domain	HormR	GIPR CELSR2	5.10e-03	25	80	2	SM00008
Domain	EGF-like_CS	CELSR2 CNTNAP1 LRP6 NID1 VWDE	5.26e-03	261	80	5	IPR013032
Domain	EGF_2	CELSR2 CNTNAP1 LRP6 NID1 VWDE	5.61e-03	265	80	5	PS01186
Domain	HRM	GIPR CELSR2	6.37e-03	28	80	2	PF02793
Domain	-	CLSTN3 CELSR2 CNTNAP1	7.89e-03	95	80	3	2.60.120.200
Pathway	REACTOME_SODIUM_PROTON_EXCHANGERS	SLC9A8 SLC9A2 SLC9A5	5.75e-06	9	59	3	M27337
Pathway	REACTOME_SODIUM_PROTON_EXCHANGERS	SLC9A8 SLC9A2 SLC9A5	5.75e-06	9	59	3	MM15079
Pubmed	Modulating the function of human serine racemase and human serine dehydratase by protein engineering.	SRR SDS	5.23e-06	2	80	2	23112234
Pubmed	A role for huntington disease protein in dendritic RNA granules.	AGO2 HTT	5.23e-06	2	80	2	20185826
Pubmed	Functional characterization of the sodium/hydrogen exchanger 8 and its role in proliferation of colonic epithelial cells.	SLC9A8 SLC9A2	5.23e-06	2	80	2	34288721
Pubmed	Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies.	AGO2 HTT	5.23e-06	2	80	2	18669659
Pubmed	Update of genetic variants in CEP120 and CC2D2A-With an emphasis on genotype-phenotype correlations, tissue specific transcripts and exploring mutation specific exon skipping therapies.	CEP120 CC2D2A	5.23e-06	2	80	2	33486889
Pubmed	Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.	ATXN1 HTT	5.23e-06	2	80	2	34504195
Pubmed	Artificial miRNAs targeting CAG repeat expansion in ORFs cause rapid deadenylation and translation inhibition of mutant transcripts.	AGO2 HTT	5.23e-06	2	80	2	32696070
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	CAD ANAPC1 IGHG2 CNTNAP1 BMS1 DOCK7	7.49e-06	202	80	6	33005030
Pubmed	Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef.	SLC9A8 SLC9A2 SLC9A5	9.33e-06	18	80	3	24874739
Pubmed	Altered acquisition and extinction of amphetamine-paired context conditioning in genetic mouse models of altered NMDA receptor function.	SRR SDS	1.57e-05	3	80	2	22763616
Pubmed	NHE2X3 DKO mice exhibit gender-specific NHE8 compensation.	SLC9A8 SLC9A2	1.57e-05	3	80	2	21252044
Pubmed	dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1.	ATXN1 HTT	1.57e-05	3	80	2	18166084
Pubmed	Molecular Sensors of Temperature, Pressure, and Pain with Special Focus on TRPV1, TRPM8, and PIEZO2 Ion Channels.	PIEZO2 TRPM8	1.57e-05	3	80	2	34825354
Pubmed	Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.	CEP120 SGSM2 SRR	2.29e-05	24	80	3	19584346
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	CELSR2 LRP6 PTCH1	2.93e-05	26	80	3	37228654
Pubmed	MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity.	AGO2 UPF1	3.13e-05	4	80	2	34517762
Pubmed	Is the 31 CAG repeat allele of the spinocerebellar ataxia 1 (SCA1) gene locus non-specifically associated with trinucleotide expansion diseases?	ATXN1 HTT	3.13e-05	4	80	2	11807410
Pubmed	Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition.	ATXN1 HTT	3.13e-05	4	80	2	24706768
Pubmed	Expanded CAG Repeats in ATXN1, ATXN2, ATXN3, and HTT in the 1000 Genomes Project.	ATXN1 HTT	3.13e-05	4	80	2	33159825
Pubmed	MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.	AGO2 UPF1	3.13e-05	4	80	2	24726324
Pubmed	Heterozygous mutations of FREM1 are associated with an increased risk of isolated metopic craniosynostosis in humans and mice.	NID1 FREM1	3.13e-05	4	80	2	21931569
Pubmed	Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.	PTCH1 ZFX	5.20e-05	5	80	2	25164012
Pubmed	Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity.	PIEZO2 PTCH1	5.20e-05	5	80	2	36323321
Pubmed	Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.	NID1 FREM1	5.20e-05	5	80	2	17596926
Pubmed	A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.	ATXN1 HTT	7.79e-05	6	80	2	23652004
Pubmed	Novel lethal mouse mutants produced in balancer chromosome screens.	LRP6 FREM1	7.79e-05	6	80	2	16466971
Pubmed	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	ZNF462 BNC2 PTPDC1 CEP120 PTCH1	9.67e-05	198	80	5	20881960
Pubmed	A cellular system that degrades misfolded proteins and protects against neurodegeneration.	ATXN1 HTT	1.09e-04	7	80	2	24882209
Pubmed	Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-binding protein, is expressed in intestinal epithelium.	SLC9A2 SLC9A5	1.09e-04	7	80	2	12576672
Pubmed	NHE1 is the sodium-hydrogen exchanger active in acute intracellular pH regulation in preimplantation mouse embryos.	SLC9A2 SLC9A5	1.09e-04	7	80	2	23677982
Pubmed	The ins and outs of a polyglutamine neurodegenerative disease: spinocerebellar ataxia type 1 (SCA1).	ATXN1 HTT	1.09e-04	7	80	2	10860780
Pubmed	Comparison of the number of triplets in SCA1, MJD/SCA3, HD, SBMA, DRPLA, MD, FRAXA and FRDA genes in schizophrenic patients and a healthy population.	ATXN1 HTT	1.09e-04	7	80	2	11121205
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	AGO2 PA2G4 NID1 UPF1 CACYBP ZFX HTT	1.14e-04	475	80	7	31040226
Pubmed	RNA association and nucleocytoplasmic shuttling by ataxin-1.	ATXN1 HTT	1.45e-04	8	80	2	15615787
Pubmed	Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.	COL6A3 NID1	1.45e-04	8	80	2	12766770
Pubmed	A sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1+ smooth muscle progenitor cells.	ATXN1 PTCH1	1.86e-04	9	80	2	18591670
Pubmed	Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination.	AGO2 ATXN1	1.86e-04	9	80	2	24326307
Pubmed	Familial pure proximal renal tubular acidosis--a clinical and genetic study.	SLC9A8 SLC9A2	1.86e-04	9	80	2	17881426
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	COL6A3 FREM1	2.32e-04	10	80	2	15345741
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CAD AGO2 ANAPC1 DOCK7 UPF1 CACYBP HTT	2.76e-04	549	80	7	38280479
Pubmed	Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.	AGO2 LRP6	2.84e-04	11	80	2	28978771
Pubmed	Aerocyte specification and lung adaptation to breathing is dependent on alternative splicing changes.	COL6A3 PLOD2	2.84e-04	11	80	2	36220570
Pubmed	The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21.	AGO2 UPF1	3.40e-04	12	80	2	31732746
Pubmed	Molecular Characterization of Nodose Ganglia Development Reveals a Novel Population of Phox2b+ Glial Progenitors in Mice.	NTRK1 SCN7A	3.40e-04	12	80	2	38830761
Pubmed	Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.	NTRK1 TRPM8	3.40e-04	12	80	2	19850157
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ZNF462 CAD AGO2 CELSR2 ANAPC1 CNTNAP1 DOCK7 DCHS1 UPF1	3.68e-04	963	80	9	28671696
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	CAD ANAPC1 PA2G4 IGHG2 UTP11 SPEG BMS1 UPF1 CACYBP	3.91e-04	971	80	9	33306668
Pubmed	Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation.	NTRK1 TRPM8	4.01e-04	13	80	2	35904071
Pubmed	Wnt1 Lineage Specific Deletion of Gpr161 Results in Embryonic Midbrain Malformation and Failure of Craniofacial Skeletal Development.	LRP6 PTCH1	4.01e-04	13	80	2	34887903
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LARGE2 CLSTN3 GPAA1 CELSR2 CNTNAP1 LRP6 NID1 CACYBP PLOD2 HTT	4.27e-04	1201	80	10	35696571
Pubmed	Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.	PHKA2 ZFX	4.67e-04	14	80	2	8432533
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	CAD ANAPC1 HASPIN UPF1 CACYBP PLOD2	5.41e-04	440	80	6	34244565
Pubmed	Aerobic glycolysis tunes YAP/TAZ transcriptional activity.	CAD PA2G4 UPF1 PLOD2	5.45e-04	162	80	4	25796446
Pubmed	Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.	PIEZO2 AGO2 ADARB2	5.98e-04	71	80	3	23400010
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	NID1 FREM1	6.14e-04	16	80	2	15878328
Pubmed	Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis.	ATXN1 SCN7A	6.14e-04	16	80	2	19451621
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	COL6A3 FREM1	6.14e-04	16	80	2	16880404
Pubmed	Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development.	DCHS1 PTCH1	6.95e-04	17	80	2	32155439
Pubmed	Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning.	LRP6 PTCH1	6.95e-04	17	80	2	20724449
Pubmed	Mapping of five subtype genes for muscarinic acetylcholine receptor to mouse chromosomes.	SCN7A NID1	6.95e-04	17	80	2	10549128
Pubmed	Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.	ZNF131 CAD ZNF217 CACYBP	7.75e-04	178	80	4	27637333
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	COL6A3 CAD SRSF11 UPF1	7.91e-04	179	80	4	36261009
Pubmed	Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors.	NTRK1 TRPM8	8.71e-04	19	80	2	31801063
Pubmed	C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway.	PIEZO2 TRPM8	8.71e-04	19	80	2	38915692
Pubmed	Ciliary Hedgehog signaling regulates cell survival to build the facial midline.	CC2D2A PTCH1	8.71e-04	19	80	2	34672258
Pubmed	Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation.	LRP6 PTCH1	8.71e-04	19	80	2	18258849
Pubmed	Tlx3 and Runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors.	NTRK1 TRPM8	8.71e-04	19	80	2	22787056
Pubmed	Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor.	NTRK1 TRPM8	8.71e-04	19	80	2	24516396
Pubmed	Quantitative interaction proteomics of neurodegenerative disease proteins.	CAD ATXN1 PA2G4 NID1 HTT	9.11e-04	323	80	5	25959826
Pubmed	Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.	CELSR2 BICRAL UPF1	9.43e-04	83	80	3	9039502
Pubmed	Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation.	NTRK1 TRPM8	9.66e-04	20	80	2	33789102
Pubmed	Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain.	PIEZO2 NTRK1	9.66e-04	20	80	2	36334588
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	AGO2 UTP11 BMS1 DOCK7 UPF1	1.03e-03	332	80	5	25693804
Pubmed	Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung.	PA2G4 DOCK7	1.07e-03	21	80	2	15328023
Pubmed	ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.	NTRK1 TRPM8	1.07e-03	21	80	2	25369838
Pubmed	Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation.	NTRK1 TRPM8	1.28e-03	23	80	2	20096094
Pubmed	The Repeat Expansion Diseases: The dark side of DNA repair.	ATXN1 HTT	1.28e-03	23	80	2	26002199
Pubmed	Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.	NTRK1 TRPM8	1.28e-03	23	80	2	16446141
Pubmed	Primary cilia in murine palatal rugae development.	CELSR2 PTCH1	1.28e-03	23	80	2	31226309
Pubmed	PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation.	CEP120 CACYBP	1.40e-03	24	80	2	24710276
Pubmed	A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.	NTRK1 NID1	1.40e-03	24	80	2	9096311
Pubmed	A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.	NTRK1 TRPM8	1.40e-03	24	80	2	17553423
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	FLNC CAD AGO2 PA2G4 SRSF11 SRR UPF1	1.42e-03	725	80	7	27025967
Pubmed	Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.	CC2D2A PTCH1	1.51e-03	25	80	2	27340223
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	FLNC BMS1 UPF1 CACYBP	1.56e-03	215	80	4	35973513
Pubmed	Human transcription factor protein interaction networks.	ZNF462 ZNF131 CAD AGO2 ATXN1 BMS1 LRP6 ZNF217 UPF1 CACYBP	1.60e-03	1429	80	10	35140242
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	CEP120 DOCK7 CACYBP	1.66e-03	101	80	3	24613305
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CAD PA2G4 HDHD5 COMMD2 BMS1 COQ8B DOCK7 SRSF11 UPF1 PLOD2	1.70e-03	1440	80	10	30833792
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DOCK7 BRINP2 ZNF407	1.71e-03	102	80	3	11214970
Pubmed	Functional genomics identifies therapeutic targets for MYC-driven cancer.	SPEG NTRK1 HASPIN	1.76e-03	103	80	3	22623531
Pubmed	The transcription factor c-Maf controls touch receptor development and function.	PIEZO2 NTRK1	1.77e-03	27	80	2	22345400
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SLC9A2 CAD AGO2 PA2G4 DCHS1 UPF1 CACYBP	1.77e-03	754	80	7	35906200
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	FLNC CAD BMS1 UPF1 CACYBP ATP1A4	1.83e-03	558	80	6	27591049
Pubmed	Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.	ZNF462 HTT	1.90e-03	28	80	2	25752541
Pubmed	Single-cell analysis identifies a key role for Hhip in murine coronal suture development.	COL6A3 PTCH1	1.90e-03	28	80	2	34880220
Pubmed	Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.	ANAPC1 PTCH1	2.04e-03	29	80	2	22898775
Pubmed	RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.	CAD UPF1	2.04e-03	29	80	2	36800290
Pubmed	La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).	CAD PA2G4 CACYBP	2.12e-03	110	80	3	25940091
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	FLNC CAD UPF1 CPNE5	2.15e-03	235	80	4	30258100
Pubmed	Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.	CELSR2 DOCK7	2.18e-03	30	80	2	19936222
Cytoband	12q24.13	MAPKAPK5 SDS	8.76e-04	25	80	2	12q24.13
Cytoband	17p13	HASPIN SRR	1.62e-03	34	80	2	17p13
GeneFamily	Cadherin related	CLSTN3 DCHS1	9.93e-04	17	50	2	24
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 COL6A3 PIEZO2 SCN7A PCDHB11 NID1	8.04e-07	177	80	6	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	BNC2 FLNC PIEZO2 SPEG BRINP2 PLOD2	1.01e-06	184	80	6	b0a251030d127858e68cf164be158f209a4d720f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 COL6A3 HFM1 ADAMTS13 STOX1 PTCH1	1.04e-06	185	80	6	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CHRNA6 COL6A3 PIEZO2 SCN7A PTCH1 FREM1	1.11e-06	187	80	6	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 COL6A3 SPEG NID1 PTCH1 FREM1	1.14e-06	188	80	6	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.21e-06	190	80	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.25e-06	191	80	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.29e-06	192	80	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 SCN7A NID1 PTCH1 FREM1	1.33e-06	193	80	6	549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.33e-06	193	80	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.33e-06	193	80	6	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.33e-06	193	80	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PTPDC1 COL6A3 PIEZO2 SCN7A PTCH1 FREM1	1.37e-06	194	80	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.41e-06	195	80	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.41e-06	195	80	6	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PIEZO2 NID1 PTCH1 ADARB2 FREM1	1.46e-06	196	80	6	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	PCW_07-8.5-Mesenchymal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.46e-06	196	80	6	8e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PIEZO2 NID1 PTCH1 ADARB2 FREM1	1.46e-06	196	80	6	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.46e-06	196	80	6	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PIEZO2 NID1 PTCH1 ADARB2 FREM1	1.50e-06	197	80	6	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PIEZO2 NID1 PTCH1 ADARB2 FREM1	1.50e-06	197	80	6	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PIEZO2 NID1 PTCH1 ADARB2 FREM1	1.50e-06	197	80	6	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.54e-06	198	80	6	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.59e-06	199	80	6	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.64e-06	200	80	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.64e-06	200	80	6	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ZNF462 COL6A3 NID1 ADAMTS13 PTCH1 ATP1A4	1.64e-06	200	80	6	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.64e-06	200	80	6	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.64e-06	200	80	6	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.64e-06	200	80	6	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.64e-06	200	80	6	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 PIEZO2 SCN7A NID1 FREM1	1.64e-06	200	80	6	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Severe-Myeloid-Mast-\|Severe / Condition, Lineage, Cell class and cell subclass	ZNF462 BNC2 NTRK1 TRPM8 ATP1A4	6.42e-06	145	80	5	ce307d45425a5191882078f049f85477eec40b69
ToppCell	Severe-Myeloid-Mast\|Severe / Condition, Lineage, Cell class and cell subclass	ZNF462 BNC2 NTRK1 TRPM8 ATP1A4	6.42e-06	145	80	5	e0bfd2ffdbd6c197ef0a04e983396ebd87ef7127
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	LARGE2 CELSR2 DCHS1 UPF1 PLOD2	1.47e-05	172	80	5	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 COL6A3 SLC9A5 NID1 PTCH1	1.55e-05	174	80	5	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A FREM1	1.88e-05	181	80	5	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF462 BNC2 CLSTN3 NTRK1 VWDE	1.93e-05	182	80	5	4cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 COL6A3 NID1 ADAMTS13 PTCH1	2.09e-05	185	80	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 COL6A3 SPEG NID1 PTCH1	2.09e-05	185	80	5	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BNC2 CEP120 SCN7A NID1 ADARB2	2.09e-05	185	80	5	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	systemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PIEZO2 NTRK1 PLOD2 VWDE FREM1	2.14e-05	186	80	5	ffd4510b4435d9bf94c2ef14c629f73ab78c5d93
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPDC1 COL6A3 RNASE1 SRR PTCH1	2.14e-05	186	80	5	827f2f2ddde315d1e5970dd56f906c555ec699af
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC2 NTRK1 ATP1A4 CPNE5 FREM1	2.20e-05	187	80	5	bdcef4f3e093c3646b639a189bbe93d6f4c40f3c
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC2 NTRK1 ATP1A4 CPNE5 FREM1	2.20e-05	187	80	5	09348f1e8bbbca8dca885461937b9b1dd248b034
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC2 NTRK1 ATP1A4 CPNE5 FREM1	2.20e-05	187	80	5	0f7a42c55997e34a0d20e492e16b03e91e965335
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC2 NTRK1 ATP1A4 CPNE5 FREM1	2.20e-05	187	80	5	064730fa72f8637c3db3fc34d2e363d2b9a38f1d
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	BNC2 COL6A3 PIEZO2 SCN7A NID1	2.20e-05	187	80	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.20e-05	187	80	5	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BNC2 COL6A3 SCN7A NID1 FREM1	2.25e-05	188	80	5	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 COL6A3 SPEG NID1 PTCH1	2.25e-05	188	80	5	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	BNC2 COL6A3 SCN7A NID1 FREM1	2.25e-05	188	80	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	systemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PIEZO2 NTRK1 PLOD2 VWDE FREM1	2.25e-05	188	80	5	c613c6c7b6de8ed514253c9f9b8622c56fcc1452
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.31e-05	189	80	5	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC2 NTRK1 ATP1A4 CPNE5 FREM1	2.31e-05	189	80	5	f01158bb15df3117fae1271bf8cf8c2501422671
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF462 BNC2 FLNC SPEG CNTNAP1	2.31e-05	189	80	5	4dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF462 BNC2 FLNC SPEG CNTNAP1	2.31e-05	189	80	5	0d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 COL6A3 PIEZO2 PTCH1 FREM1	2.31e-05	189	80	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 COL6A3 PIEZO2 NID1 FREM1	2.49e-05	192	80	5	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN3 CELSR2 SGSM2 BRINP2 CPNE5	2.55e-05	193	80	5	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTRK1 SCN7A NID1 PLOD2 FREM1	2.55e-05	193	80	5	59b8186d0221fba06a16157e9d148399ed801f38
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACSL1 COL6A3 PIEZO2 SCN7A FREM1	2.55e-05	193	80	5	96c85b250d04b5f400512097d925061c6dc2906b
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTRK1 SCN7A NID1 PLOD2 FREM1	2.55e-05	193	80	5	dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1	2.55e-05	193	80	5	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.55e-05	193	80	5	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 FLNC PIEZO2 SCN7A FREM1	2.55e-05	193	80	5	e5016959f24370579a8770787e96869f264cf7b3
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN3 CELSR2 SGSM2 BRINP2 CPNE5	2.55e-05	193	80	5	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN3 CELSR2 SGSM2 BRINP2 CPNE5	2.55e-05	193	80	5	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTRK1 SCN7A NID1 PLOD2 FREM1	2.55e-05	193	80	5	03678162648bd5b1d65a5450b60c8863edbf95c7
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A NID1	2.62e-05	194	80	5	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.62e-05	194	80	5	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.62e-05	194	80	5	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.62e-05	194	80	5	99577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 COL6A3 PIEZO2 NID1 FREM1	2.62e-05	194	80	5	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.68e-05	195	80	5	70387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PIEZO2 NID1 PTCH1 ADARB2	2.68e-05	195	80	5	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	BNC2 COL6A3 SCN7A NID1 FREM1	2.68e-05	195	80	5	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	BNC2 COL6A3 PIEZO2 SCN7A NID1	2.68e-05	195	80	5	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.75e-05	196	80	5	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 PIEZO2 SCN7A PLOD2 FREM1	2.75e-05	196	80	5	308fa54385ca34e9e590967d4553b84aad96c92f
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CELSR2 BRINP2 OGDHL HFM1 SRR	2.75e-05	196	80	5	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.75e-05	196	80	5	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BNC2 COL6A3 PIEZO2 SCN7A NID1	2.75e-05	196	80	5	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC IGHG2 SPEG NTRK1 NID1	2.82e-05	197	80	5	3332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.82e-05	197	80	5	31a1852911bda38543916585fda34255fd62a134
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	BNC2 COL6A3 PIEZO2 SCN7A PLOD2	2.82e-05	197	80	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 CNTNAP1 SCN7A NID1 PTCH1	2.82e-05	197	80	5	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.82e-05	197	80	5	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 COL6A3 SCN7A PTCH1 FREM1	2.82e-05	197	80	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	BNC2 COL6A3 PIEZO2 SCN7A PLOD2	2.82e-05	197	80	5	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.89e-05	198	80	5	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	BNC2 COL6A3 PIEZO2 SCN7A NID1	2.89e-05	198	80	5	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BNC2 COL6A3 PIEZO2 SCN7A NID1	2.89e-05	198	80	5	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.89e-05	198	80	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 PIEZO2 NID1 PTCH1 FREM1	2.96e-05	199	80	5	edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCell	Fibroblasts\|World / lung cells shred on cell class, cell subclass, sample id	COL6A3 FLNC PIEZO2 SCN7A NID1	2.96e-05	199	80	5	e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BNC2 COL6A3 NID1 PTCH1 FREM1	2.96e-05	199	80	5	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	PCW_10-12-Mesenchymal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BNC2 COL6A3 PIEZO2 SCN7A FREM1	2.96e-05	199	80	5	a09292de4c4447b8eee55d401808e43b817321cc
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 PIEZO2 SCN7A PLOD2 FREM1	2.96e-05	199	80	5	eeb7d370d4dfacf705306c72ccc4919ddefacff1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial\|6m / Sample Type, Dataset, Time_group, and Cell type.	BNC2 COL6A3 PIEZO2 SCN7A NID1	3.03e-05	200	80	5	2cc98abf11f5b58707de45a2282f03d47f00f035
Disease	mean corpuscular hemoglobin concentration	GIPR ZNF131 SLC9A2 AGO2 GPAA1 ATXN1 CC2D2A CTDSP1 HFM1 PARP9 ZNF217 MYNN	3.18e-05	1105	78	12	EFO_0004528
Disease	nephrolithiasis (implicated_via_orthology)	SLC9A2 SLC9A5	6.86e-05	5	78	2	DOID:585 (implicated_via_orthology)
Disease	facial pigmentation measurement	BNC2 CEP120 COQ8B	4.69e-04	57	78	3	EFO_0006942
Disease	amyotrophic lateral sclerosis	SLC9A8 ATXN1 SCN7A CTDSP1	6.02e-04	145	78	4	MONDO_0004976
Disease	CD209 antigen measurement	CELSR2 ADAMTS13	6.15e-04	14	78	2	EFO_0008077
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	GIPR CELSR2 DOCK7 HTT	6.83e-04	150	78	4	EFO_0004611, EFO_0020947
Disease	Craniosynostosis	ZNF462 FREM1	1.27e-03	20	78	2	C0010278
Disease	sleep duration, low density lipoprotein cholesterol measurement	CELSR2 DOCK7 HTT	1.83e-03	91	78	3	EFO_0004611, EFO_0005271
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	GIPR CELSR2 DOCK7 HTT	1.98e-03	200	78	4	EFO_0004611, EFO_0020945
Disease	methionine measurement	AXDND1 NID1	2.15e-03	26	78	2	EFO_0009771
Disease	pancreatic cancer (is_marker_for)	NTRK1 CACYBP PTCH1	2.46e-03	101	78	3	DOID:1793 (is_marker_for)
Disease	Colorectal Carcinoma	FLNC CLSTN3 CAD DCHS1 NID1 ZNF217 ADARB2	2.57e-03	702	78	7	C0009402

Protein segments in the cluster

Peptide	Gene	Start	Entry
EVNFVAQENHAVISI	CNTNAP1	446	P78357
VHVRVNDVNEFAPVF	CLSTN3	131	Q9BQT9
HPTQVEIVQSNVVFD	BNC2	156	Q6ZN30
EPVAQVFVHGESLQA	ACSL1	581	P33121
GVHEVVFAPVTEEQA	GIPR	351	P48546
PDHVVVFNVQRDTDA	CELSR2	1161	Q9HCU4
VAVIQFAVGEHRAQV	ATXN1	626	P54253
VFQDEVGPTHELVQS	BMS1	361	Q14692
VAVGPDVFQAHQEDT	ADAMTS13	86	Q76LX8
VFQQPVIFLGADVTH	AGO2	586	Q9UKV8
VHAPVFAVAVEVNGL	ADARB2	151	Q9NS39
AEAQQFLHFVEASPV	LARGE2	466	Q8N3Y3
ADVIVNSVNPHDITV	PARP9	331	Q8IXQ6
TELDVPHNVQVAAVV	ANAPC1	1241	Q9H1A4
VAHTFVVDVAQGTQV	PA2G4	121	Q9UQ80
AAFVLHVTDVNDNAP	DCHS1	456	Q96JQ0
HFALAPVTIEVQDVN	DCHS1	2686	Q96JQ0
NVSFPASVQLHTAVE	NTRK1	281	P04629
GNIFVNEITVHVVAV	OR10AG1	181	Q8NH19
VQIIEVFANSVQFPH	MAPKAPK5	76	Q8IW41
VATQHFPVAEAEAVV	GPAA1	451	O43292
PEVAAIVNFITAHGN	CPA5	301	Q8WXQ8
VARVVNAPIFHVNAD	OGDHL	451	Q9ULD0
AVETFHQQHPQVIDV	NID1	356	P14543
EHLAFLPQVDSAVVA	COMMD2	11	Q86X83
ATVHQLSAFQPDVVI	EEF2KMT	231	Q96G04
VHQVPTENVQVHFTE	CACYBP	96	Q9HB71
NADFIIPVEIDGVVH	CTDSP1	111	Q9GZU7
TVLQPAHFTVQTVDA	FLNC	291	Q14315
NSAEFVLHVEVFPVN	FREM1	871	Q5H8C1
VENTFPAQDIVHTVT	MYNN	241	Q9NPC7
FVVTAQIAHPDGIAV	LRP6	396	O75581
QTIPVDVEEAFLAHA	PTPDC1	696	A2A3K4
AVDVHPNVSIGVFIE	PLOD2	291	O00469
STVIIHVIDVNDNAP	PCDHB11	331	Q9Y5F2
FSVAFQPHDIQEVTE	HFM1	241	A2PYH4
GAPVEVTHNFQVDFV	UPF1	411	Q92900
VHFEVAITQLANVDE	CHRNA6	61	Q15825
VHFILEAVAVQPGEQ	HTT	2311	P42858
AEDEGQPITFAVQVH	IPCEF1	231	Q8WWN9
DQFHLVPNHIVVSAE	BICRAL	876	Q6AI39
TGVHNIDVPNVEFAL	CC2D2A	1581	Q9P2K1
NVEVVAVSSIHTQDP	DOCK7	721	Q96N67
TEINQHPVTVEGAFT	CEP120	296	Q8N960
VPQHIDVDSVSVLQA	AXDND1	656	Q5T1B0
FARVAVVQHAPSESV	COL6A3	2661	P12111
EEVPFAAASIGQVHQ	COQ8B	211	Q96D53
GEVFQTIADHTPVAI	HASPIN	496	Q8TF76
VVVDVSHEDPEVQFN	IGHG2	141	P01859
IVTDVNEAPQFSQHV	CDH17	556	Q12864
FQEHPIFSEVISDQE	SDS	236	P20132
PVVTHVARNAAAVQD	CPNE5	436	Q9HCH3
PDVVVQVTVLAENNH	PHKA2	436	P46019
PHTVAAVLEAVAQAA	RSAD1	106	Q9HA92
VEQFDVATHLQTAPE	UTP11	146	Q9Y3A2
EVIQSHSIFEQGPAE	POLR3D	101	P05423
SHVVNDVNEAVQLVF	HDHD5	401	Q9BXW7
AHQVIVEATENPVFA	PTCH1	1251	Q13635
VEATENPVFAHSTVV	PTCH1	1256	Q13635
TPGTAVVEQQHSVEF	SGSM2	686	O43147
DPVATIAIFNALHVD	SLC9A8	201	Q9Y2E8
PVAVLAVFEEVHVNE	SLC9A5	186	Q14940
AAVLSQHFQTVSPEV	SRR	291	Q9GZT4
VNTFVHEPLVDVQNV	RNASE1	71	P07998
ATAAAVVPEQHASVA	BRINP2	36	Q9C0B6
AVGQTPIAAEIEHFI	ATP1A4	286	Q13733
PHVQSVAIESQEFFA	VWDE	276	Q8N2E2
APGFQVVHLNAVTVD	ZMYND19	81	Q96E35
PASVTVTFNHVEAQV	SPEG	1406	Q15772
PDSAVVAQHLTNTVF	SRSF11	86	Q05519
AVDPVAVLAVFENIH	SLC9A2	216	Q9UBY0
HTQDVQEAPVAAEVT	STOX1	251	Q6ZVD7
DVSVFVIPLHSQGQE	PPM1M	441	Q96MI6
ESVHVTFPEQQTAVR	PIEZO2	2081	Q9H5I5
PIVAHAEQQTVAAVL	CAD	1586	P27708
AIVFGAEVEQVHLVA	nan	36	Q96MT0
VHNFVPDDPDSVVIQ	ZFX	51	P17010
VHTAFLQPTDVAEDN	ZNF462	26	Q96JM2
PATINEVVQVHAAES	ZNF217	196	O75362
AIDSVAVNIQPHFEV	SCN7A	1151	Q01118
VQVDSAQVTVEQVHP	ZNF131	486	P52739
AAVEVLTQVVHPSAA	ZNF407	2051	Q9C0G0
VEATDQHFIAQPGVQ	TRPM8	661	Q7Z2W7