Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	lyase activity	PTGES2 NPR2 CA13 ADCY7 GGCX FASN CA2 CA3	1.52e-05	212	104	8	GO:0016829
GeneOntologyMolecularFunction	palmitoyl-CoA 9-desaturase activity	SCD5 SCD	2.69e-05	2	104	2	GO:0032896
GeneOntologyMolecularFunction	carbonate dehydratase activity	CA13 CA2 CA3	7.32e-05	16	104	3	GO:0004089
GeneOntologyMolecularFunction	transition metal ion binding	PAPPA2 NAALADL1 ADAMTS3 CYP11A1 CA13 MMP21 PGLYRP2 CHD4 SCD5 L3MBTL1 SYTL4 PIM1 SCD ZFHX3 CA2 CA3 DNMT1	1.33e-04	1189	104	17	GO:0046914
GeneOntologyMolecularFunction	stearoyl-CoA 9-desaturase activity	SCD5 SCD	1.60e-04	4	104	2	GO:0004768
GeneOntologyMolecularFunction	NAD transmembrane transporter activity	SLC25A51 SLC25A52	2.66e-04	5	104	2	GO:0051724
GeneOntologyMolecularFunction	acyl-CoA desaturase activity	SCD5 SCD	2.66e-04	5	104	2	GO:0016215
GeneOntologyMolecularFunction	hydro-lyase activity	CA13 FASN CA2 CA3	3.27e-04	63	104	4	GO:0016836
GeneOntologyMolecularFunction	zinc ion binding	PAPPA2 NAALADL1 ADAMTS3 CA13 MMP21 PGLYRP2 CHD4 L3MBTL1 SYTL4 ZFHX3 CA2 CA3 DNMT1	7.29e-04	891	104	13	GO:0008270
GeneOntologyMolecularFunction	carbon-oxygen lyase activity	CA13 FASN CA2 CA3	8.89e-04	82	104	4	GO:0016835
GeneOntologyBiologicalProcess	mitochondrial NAD transmembrane transport	SLC25A51 SLC25A52	2.47e-05	2	103	2	GO:1990549
GeneOntologyBiologicalProcess	monounsaturated fatty acid biosynthetic process	SCD5 SCD	2.47e-05	2	103	2	GO:1903966
GeneOntologyBiologicalProcess	tarsal gland development	SCD5 SCD	7.38e-05	3	103	2	GO:1903699
GeneOntologyBiologicalProcess	monounsaturated fatty acid metabolic process	SCD5 SCD	7.38e-05	3	103	2	GO:1903964
GeneOntologyCellularComponent	apical part of cell	PAPPA2 NAALADL1 HIP1R CDH23 SLC3A1 ITPR3 DUOX1 SLC9A3 SYTL4 SLC5A6 CNTFR CA2	4.65e-05	592	106	12	GO:0045177
GeneOntologyCellularComponent	apical plasma membrane	PAPPA2 NAALADL1 HIP1R SLC3A1 ITPR3 DUOX1 SLC9A3 SYTL4 SLC5A6 CNTFR	1.86e-04	487	106	10	GO:0016324
Domain	Acyl-CoA_DS	SCD5 SCD	3.13e-05	2	105	2	IPR015876
Domain	FATTY_ACID_DESATUR_1	SCD5 SCD	3.13e-05	2	105	2	PS00476
Domain	FADS-1_CS	SCD5 SCD	3.13e-05	2	105	2	IPR001522
Domain	CA2	CA13 CA2	3.13e-05	2	105	2	IPR018443
Domain	Carbonic_anhydrase_a-class_CS	CA13 CA2 CA3	3.66e-05	12	105	3	IPR018338
Domain	Carbonic_anhydrase_a-class	CA13 CA2 CA3	7.48e-05	15	105	3	IPR023561
Domain	ALPHA_CA_1	CA13 CA2 CA3	7.48e-05	15	105	3	PS00162
Domain	Carb_anhydrase	CA13 CA2 CA3	1.11e-04	17	105	3	PF00194
Domain	Carb_anhydrase	CA13 CA2 CA3	1.11e-04	17	105	3	SM01057
Domain	-	CA13 CA2 CA3	1.11e-04	17	105	3	3.10.200.10
Domain	ALPHA_CA_2	CA13 CA2 CA3	1.11e-04	17	105	3	PS51144
Domain	Carbonic_anhydrase_a	CA13 CA2 CA3	1.11e-04	17	105	3	IPR001148
Domain	CEBP_ZZ	CPEB2 CPEB4	1.86e-04	4	105	2	PF16366
Domain	RRM_7	CPEB2 CPEB4	1.86e-04	4	105	2	PF16367
Domain	CEBP_ZZ	CPEB2 CPEB4	1.86e-04	4	105	2	IPR032296
Domain	GST_C	PTGES2 GSTT2B GSTT2	4.09e-04	26	105	3	IPR004046
Domain	GST_C	PTGES2 GSTT2B GSTT2	4.09e-04	26	105	3	PF00043
Domain	Glutathione_S-Trfase_N	PTGES2 GSTT2B GSTT2	4.58e-04	27	105	3	IPR004045
Domain	FA_desaturase_dom	SCD5 SCD	8.57e-04	8	105	2	IPR005804
Domain	FA_desaturase	SCD5 SCD	8.57e-04	8	105	2	PF00487
Domain	GPS	ADGRG1 CELSR3 ADGRD2	9.10e-04	34	105	3	SM00303
Domain	GST_CTER	PTGES2 GSTT2B GSTT2	9.10e-04	34	105	3	PS50405
Domain	GPS	ADGRG1 CELSR3 ADGRD2	9.91e-04	35	105	3	PF01825
Domain	GPS	ADGRG1 CELSR3 ADGRD2	1.08e-03	36	105	3	PS50221
Domain	GPS	ADGRG1 CELSR3 ADGRD2	1.17e-03	37	105	3	IPR000203
Domain	Glutathione-S-Trfase_C-like	PTGES2 GSTT2B GSTT2	1.36e-03	39	105	3	IPR010987
Domain	-	PTGES2 GSTT2B GSTT2	1.36e-03	39	105	3	1.20.1050.10
Domain	FYVE_2	SYTL4 SYTL5	1.67e-03	11	105	2	PF02318
Domain	XK-related	XKR3 XKR5	1.67e-03	11	105	2	PF09815
Domain	XK_rel	XKR3 XKR5	1.67e-03	11	105	2	IPR018629
Domain	RABBD	SYTL4 SYTL5	1.99e-03	12	105	2	PS50916
Domain	Rab_BD	SYTL4 SYTL5	1.99e-03	12	105	2	IPR010911
Domain	7tm_2	ADGRG1 CELSR3 ADGRD2	2.79e-03	50	105	3	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRG1 CELSR3 ADGRD2	2.79e-03	50	105	3	PS00650
Domain	A/G_cyclase_CS	NPR2 ADCY7	4.03e-03	17	105	2	IPR018297
Domain	-	NPR2 ADCY7	4.52e-03	18	105	2	3.30.70.1230
Domain	Nucleotide_cyclase	NPR2 ADCY7	4.52e-03	18	105	2	IPR029787
Domain	GPCR_2_secretin-like	ADGRG1 CELSR3 ADGRD2	4.68e-03	60	105	3	IPR000832
Domain	GPCR_2-like	ADGRG1 CELSR3 ADGRD2	4.68e-03	60	105	3	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRG1 CELSR3 ADGRD2	4.91e-03	61	105	3	PS50261
Domain	Guanylate_cyc	NPR2 ADCY7	5.03e-03	19	105	2	PF00211
Domain	GUANYLATE_CYCLASE_2	NPR2 ADCY7	5.03e-03	19	105	2	PS50125
Domain	A/G_cyclase	NPR2 ADCY7	5.03e-03	19	105	2	IPR001054
Domain	GUANYLATE_CYCLASE_1	NPR2 ADCY7	5.03e-03	19	105	2	PS00452
Domain	CYCc	NPR2 ADCY7	5.03e-03	19	105	2	SM00044
Domain	TSP_1	ADAMTS3 SSPOP CILP2	5.37e-03	63	105	3	PF00090
Pathway	REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE	CA13 CA2 CA3	4.02e-05	12	82	3	M671
Pathway	WP_ELONGATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS	SCD5 FASN SCD	4.02e-05	12	82	3	MM17077
Pathway	REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE	CA13 CA2 CA3	4.02e-05	12	82	3	MM14574
Pathway	WP_OMEGA9_FATTY_ACID_SYNTHESIS	SCD5 FASN SCD	6.59e-05	14	82	3	M39780
Pathway	KEGG_NITROGEN_METABOLISM	CA13 CA2 CA3	3.09e-04	23	82	3	M4629
Pathway	WP_FATTY_ACID_BIOSYNTHESIS	SCD5 FASN SCD	3.09e-04	23	82	3	MM15885
Pubmed	Stearoyl-CoA Desaturase 1 Activity Determines the Maintenance of DNMT1-Mediated DNA Methylation Patterns in Pancreatic β-Cells.	SCD5 SCD DNMT1	2.83e-08	3	107	3	32961871
Pubmed	γ-Tocotrienol attenuates triglyceride through effect on lipogenic gene expressions in mouse hepatocellular carcinoma Hepa 1-6.	SCD5 FASN SCD	1.13e-07	4	107	3	23727646
Pubmed	Peroxisome proliferator-activated receptor alpha deficiency abolishes the response of lipogenic gene expression to re-feeding: restoration of the normal response by activation of liver X receptor alpha.	SCD5 FASN SCD	2.82e-07	5	107	3	18079124
Pubmed	MicroRNA-103 represses hepatic de novo lipogenesis and alleviates NAFLD via targeting FASN and SCD1.	SCD5 FASN SCD	5.62e-07	6	107	3	32035613
Pubmed	Carbonic anhydrases in the mouse harderian gland.	CA13 CA2 CA3	1.57e-06	8	107	3	20820888
Pubmed	cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells.	SCD5 FASN SCD	2.35e-06	9	107	3	23637738
Pubmed	Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.	PPP1R15A SCD5 FASN SCD	3.23e-06	33	107	4	27416896
Pubmed	Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1).	SCD5 FASN SCD	3.34e-06	10	107	3	12588883
Pubmed	Expression patterns and subcellular localization of carbonic anhydrases are developmentally regulated during tooth formation.	CA13 CA2 CA3	4.59e-06	11	107	3	24789143
Pubmed	Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.	SCD5 FASN SCD	4.59e-06	11	107	3	14668353
Pubmed	MED1 is a lipogenesis coactivator required for postnatal adipose expansion.	SCD5 FASN SCD	4.59e-06	11	107	3	33888555
Pubmed	A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system.	CA13 CA2 CA3	6.10e-06	12	107	3	17362527
Pubmed	Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion.	SCD5 FASN SCD	6.10e-06	12	107	3	27307439
Pubmed	Nucleotide sequence of mouse spermidine synthase cDNA.	SCD5 FASN SCD	7.92e-06	13	107	3	7803821
Pubmed	Obesity resistance of the stearoyl-CoA desaturase-deficient (scd1-/-) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation.	SCD5 SCD	9.38e-06	2	107	2	17391062
Pubmed	Increased hydrophilic plasma bile acids are correlated with protection from adiposity in skin-specific stearoyl-CoA desaturase-1 deficient mice.	SCD5 SCD	9.38e-06	2	107	2	29965978
Pubmed	Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis.	SCD5 SCD	9.38e-06	2	107	2	36124130
Pubmed	[Role of stearoyl-CoA desaturase in regulation of energy metabolism].	SCD5 SCD	9.38e-06	2	107	2	18788462
Pubmed	beta-Adrenergic control of stearoyl-CoA desaturase 1 repression in relation to sympathoadrenal regulation of thermogenesis.	SCD5 SCD	9.38e-06	2	107	2	16801925
Pubmed	Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.	SCD5 SCD	9.38e-06	2	107	2	10545940
Pubmed	Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism.	SCD5 SCD	9.38e-06	2	107	2	21573029
Pubmed	Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells.	SCD5 SCD	9.38e-06	2	107	2	15610069
Pubmed	Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates.	SCD5 SCD	9.38e-06	2	107	2	15907797
Pubmed	Nuclear factor 1 is essential for the expression of stearoyl-CoA desaturase 1 gene during preadipocyte differentiation.	SCD5 SCD	9.38e-06	2	107	2	9689914
Pubmed	Dietary fat is a lipid source in 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD)-elicited hepatic steatosis in C57BL/6 mice.	SCD5 SCD	9.38e-06	2	107	2	22539624
Pubmed	Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate.	SCD5 SCD	9.38e-06	2	107	2	19910642
Pubmed	The expression of the gene asebia in the laboratory mouse. I. Epidermis and dermis.	SCD5 SCD	9.38e-06	2	107	2	631559
Pubmed	SCD1 is nutritionally and spatially regulated in the intestine and influences systemic postprandial lipid homeostasis and gut-liver crosstalk.	SCD5 SCD	9.38e-06	2	107	2	35718096
Pubmed	Skin lipids of a normal and mutant (asebic) mouse strain.	SCD5 SCD	9.38e-06	2	107	2	5924301
Pubmed	SCD1 promotes lipid mobilization in subcutaneous white adipose tissue.	SCD5 SCD	9.38e-06	2	107	2	32978274
Pubmed	Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle.	SCD5 SCD	9.38e-06	2	107	2	12960377
Pubmed	Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1.	SCD5 SCD	9.38e-06	2	107	2	16829692
Pubmed	Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1.	GSTT2B GSTT2	9.38e-06	2	107	2	9854036
Pubmed	Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism.	SCD5 SCD	9.38e-06	2	107	2	12364560
Pubmed	Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat.	SCD5 SCD	9.38e-06	2	107	2	17127673
Pubmed	A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis.	SCD5 SCD	9.38e-06	2	107	2	11441127
Pubmed	Loss of stearoyl-CoA desaturase activity leads to free cholesterol synthesis through increased Xbp-1 splicing.	SCD5 SCD	9.38e-06	2	107	2	20923962
Pubmed	SCD1 inhibition during 3T3-L1 adipocyte differentiation remodels triacylglycerol, diacylglycerol and phospholipid fatty acid composition.	SCD5 SCD	9.38e-06	2	107	2	25959085
Pubmed	Metabolic rerouting via SCD1 induction impacts X-linked adrenoleukodystrophy.	SCD5 SCD	9.38e-06	2	107	2	33690217
Pubmed	Human stearoyl-CoA desaturase 1 (SCD-1) gene expression is negatively regulated by thyroid hormone without direct binding of thyroid hormone receptor to the gene promoter.	SCD5 SCD	9.38e-06	2	107	2	23221600
Pubmed	Lung fibroblasts promote metastatic colonization through upregulation of stearoyl-CoA desaturase 1 in tumor cells.	SCD5 SCD	9.38e-06	2	107	2	29326439
Pubmed	Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol.	SCD5 SCD	9.38e-06	2	107	2	10484602
Pubmed	Scd1 plays a tumor-suppressive role in survival of leukemia stem cells and the development of chronic myeloid leukemia.	SCD5 SCD	9.38e-06	2	107	2	22431519
Pubmed	Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia.	SCD5 SCD	9.38e-06	2	107	2	12401889
Pubmed	Scd3--a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin.	SCD5 SCD	9.38e-06	2	107	2	11161812
Pubmed	Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression.	SCD5 SCD	9.38e-06	2	107	2	8790349
Pubmed	Early-life exposure to bisphenol A induces dysregulation of lipid homeostasis by the upregulation of SCD1 in male mice.	SCD5 SCD	9.38e-06	2	107	2	35341816
Pubmed	Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Delta6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse.	SCD5 SCD	9.38e-06	2	107	2	12454277
Pubmed	Stearoyl-CoA desaturase 1 activity is required for autophagosome formation.	SCD5 SCD	9.38e-06	2	107	2	25023287
Pubmed	Combined deletion of SCD1 from adipose tissue and liver does not protect mice from obesity.	SCD5 SCD	9.38e-06	2	107	2	22669918
Pubmed	Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue.	SCD5 SCD	9.38e-06	2	107	2	15494611
Pubmed	Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease.	SCD5 SCD	9.38e-06	2	107	2	22046234
Pubmed	Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity.	SCD5 SCD	9.38e-06	2	107	2	12177411
Pubmed	Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase.	SCD5 SCD	9.38e-06	2	107	2	18832746
Pubmed	Stearoyl-CoA desaturase 1 deficiency protects mice from immune-mediated liver injury.	SCD5 SCD	9.38e-06	2	107	2	19002112
Pubmed	Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target.	SCD5 SCD	9.38e-06	2	107	2	25675381
Pubmed	Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid.	SCD5 SCD	9.38e-06	2	107	2	11533264
Pubmed	Glycerol regulates stratum corneum hydration in sebaceous gland deficient (asebia) mice.	SCD5 SCD	9.38e-06	2	107	2	12713573
Pubmed	Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis.	SCD5 SCD	9.38e-06	2	107	2	18054317
Pubmed	Membrane topology of mouse stearoyl-CoA desaturase 1.	SCD5 SCD	9.38e-06	2	107	2	16275639
Pubmed	Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats.	SCD5 SCD	9.38e-06	2	107	2	12419843
Pubmed	Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment.	SCD5 SCD	9.38e-06	2	107	2	15210843
Pubmed	Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet.	SCD5 SCD	9.38e-06	2	107	2	18381840
Pubmed	Identification of a novel SCD gene and expression of the SCD gene family in mouse skin.	SCD5 SCD	9.38e-06	2	107	2	10674390
Pubmed	Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity.	SCD5 SCD	9.38e-06	2	107	2	30118512
Pubmed	Asebia-2J (Scd1(ab2J)): a new allele and a model for scarring alopecia.	SCD5 SCD	9.38e-06	2	107	2	10854228
Pubmed	Diet-induced changes in stearoyl-CoA desaturase 1 expression in obesity-prone and -resistant mice.	SCD5 SCD	9.38e-06	2	107	2	15340109
Pubmed	Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart.	SCD5 SCD	9.38e-06	2	107	2	18042664
Pubmed	Alpha-linolenic acid increases cholesterol efflux in macrophage-derived foam cells by decreasing stearoyl CoA desaturase 1 expression: evidence for a farnesoid-X-receptor mechanism of action.	SCD5 SCD	9.38e-06	2	107	2	21658928
Pubmed	Carbonic anhydrase II binds to and increases the activity of the epithelial sodium-proton exchanger, NHE3.	SLC9A3 CA2	9.38e-06	2	107	2	26041446
Pubmed	Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro.	SCD5 SCD	9.38e-06	2	107	2	17033839
Pubmed	Clofibrate treatment increases stearoyl-CoA desaturase mRNA level and enzyme activity in mouse liver.	SCD5 SCD	9.38e-06	2	107	2	8541340
Pubmed	Polyunsaturated fatty acids do not activate AMP-activated protein kinase in mouse tissues.	SCD5 SCD	9.38e-06	2	107	2	15916750
Pubmed	Overexpression of stearoyl-coenzyme A desaturase 1 in macrophages promotes reverse cholesterol transport.	SCD5 SCD	9.38e-06	2	107	2	23747827
Pubmed	Interplay between Thyroid Hormones and Stearoyl-CoA Desaturase 1 in the Regulation of Lipid Metabolism in the Heart.	SCD5 SCD	9.38e-06	2	107	2	33374300
Pubmed	Reduced SCD1 activity alters markers of fatty acid reesterification, glyceroneogenesis, and lipolysis in murine white adipose tissue and 3T3-L1 adipocytes.	SCD5 SCD	9.38e-06	2	107	2	28659287
Pubmed	Polyunsaturated fatty acids inhibit hepatic stearoyl-CoA desaturase-1 gene in diabetic mice.	SCD5 SCD	9.38e-06	2	107	2	8729090
Pubmed	Identification and characterization of GSTT3, a third murine Theta class glutathione transferase.	GSTT2B GSTT2	9.38e-06	2	107	2	12038961
Pubmed	Stearoyl-CoA desaturase regulates inflammatory gene expression by changing DNA methylation level in 3T3 adipocytes.	SCD5 SCD	9.38e-06	2	107	2	25130896
Pubmed	Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series.	SCD5 SCD	9.38e-06	2	107	2	22101133
Pubmed	Compartmentalization of stearoyl-coenzyme A desaturase 1 activity in HepG2 cells.	SCD5 SCD	9.38e-06	2	107	2	18599738
Pubmed	Structure and Mechanism of a Unique Diiron Center in Mammalian Stearoyl-CoA Desaturase.	SCD5 SCD	9.38e-06	2	107	2	32470559
Pubmed	Role of stearoyl-CoA desaturase-1 in skeletal muscle function and metabolism.	SCD5 SCD	9.38e-06	2	107	2	23941875
Pubmed	Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells.	SCD5 SCD	9.38e-06	2	107	2	30930246
Pubmed	Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver.	SCD5 SCD	9.38e-06	2	107	2	1350282
Pubmed	Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.	GSTT2B GSTT2	9.38e-06	2	107	2	19424424
Pubmed	Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.	SCD5 SCD	9.38e-06	2	107	2	28143772
Pubmed	cDNA nucleotide sequence coding for stearoyl-CoA desaturase and its expression in the zebrafish (Danio rerio) embryo.	SCD5 SCD	9.38e-06	2	107	2	14579408
Pubmed	The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1.	SCD5 SCD	9.38e-06	2	107	2	10899171
Pubmed	Susceptibility of podocytes to palmitic acid is regulated by stearoyl-CoA desaturases 1 and 2.	SCD5 SCD	9.38e-06	2	107	2	23867797
Pubmed	Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis.	SCD5 SCD	9.38e-06	2	107	2	18249173
Pubmed	Differential expression of hepatic stearoyl-CoA desaturase gene 1 in male and female mice.	SCD5 SCD	9.38e-06	2	107	2	8954132
Pubmed	Overexpression of stearoyl-CoA desaturase 1 in bone-marrow mesenchymal stem cells increases osteogenesis.	SCD5 SCD	9.38e-06	2	107	2	24088802
Pubmed	Hepatic oleate regulates adipose tissue lipogenesis and fatty acid oxidation.	SCD5 SCD	9.38e-06	2	107	2	25555387
Pubmed	Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins.	SCD5 SCD	9.38e-06	2	107	2	24055053
Pubmed	Stearoyl-CoA Desaturase-1 Protects Cells against Lipotoxicity-Mediated Apoptosis in Proximal Tubular Cells.	SCD5 SCD	9.38e-06	2	107	2	27834856
Pubmed	Mammalian class theta GST and differential susceptibility to carcinogens: a review.	GSTT2B GSTT2	9.38e-06	2	107	2	11018744
Pubmed	Characterization of a cDNA and gene encoding the mouse theta class glutathione transferase mGSTT2 and its localization to chromosome 10B5-C1.	GSTT2B GSTT2	9.38e-06	2	107	2	8617493
Pubmed	Hepatic oleate regulates liver stress response partially through PGC-1α during high-carbohydrate feeding.	SCD5 SCD	9.38e-06	2	107	2	26976120
Pubmed	Stearoyl-CoA desaturase 1 deficiency exacerbates palmitate-induced lipotoxicity by the formation of small lipid droplets in pancreatic β-cells.	SCD5 SCD	9.38e-06	2	107	2	37054998
GeneFamily	Carbonic anhydrases	CA13 CA2 CA3	6.25e-05	18	79	3	460
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	NPR2 SBF1 DENND6B	1.72e-04	25	79	3	504
GeneFamily	Fatty acid desaturases	SCD5 SCD	5.19e-04	8	79	2	553
GeneFamily	Synaptotagmin like tandem C2 proteins	SYTL4 SYTL5	8.29e-04	10	79	2	822
GeneFamily	Blood group antigens\|XK related family	XKR3 XKR5	1.01e-03	11	79	2	955
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZHX2 ZFHX3	1.91e-03	15	79	2	529
GeneFamily	Ankyrin repeat domain containing	ANKRD42 ANKLE1 ANKRD44 IBTK DZANK1	4.16e-03	242	79	5	403
GeneFamily	Glutathione S-transferases	GSTT2B GSTT2	5.30e-03	25	79	2	567
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	ABHD18 PILRB CDH23 ADGRG1 GAL3ST4 PPP1R15A ADCY7 ITPR3 MOGS SBF1 FKTN TTC31 SGSM2 DAPP1 DENND6B ZFHX3 DNMT1	1.53e-07	905	107	17	M40865
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN	ABHD18 PILRB CDH23 PPP1R15A ADCY7 ITPR3 MOGS TTC31 SGSM2 DAPP1 ZFHX3 DNMT1	1.11e-05	634	107	12	M40866
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG9 ITPR3 DUOX1 FASN ASPH WIF1 FAM20A CA2	2.53e-08	196	107	8	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	ASK440-Epithelial-Type_2\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	ITPR3 DUOX1 FASN SCD ASPH WIF1 FAM20A CA2	2.53e-08	196	107	8	754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG9 ITPR3 DUOX1 FASN ASPH WIF1 FAM20A CA2	2.64e-08	197	107	8	bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG9 ITPR3 DUOX1 FASN SCD ASPH WIF1 CA2	2.85e-08	199	107	8	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	droplet-Liver-LIVER_HEP-30m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD18 AMDHD1 ANGPTL1 GSTT2 CPEB4 AGXT CA3	7.85e-08	150	107	7	42fd42a0be918a77aca4e0c91f068bdd5a5d9286
ToppCell	droplet-Liver-LIVER_HEP-30m-Epithelial-Hepatocyte_(Midlobular)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD18 AMDHD1 ANGPTL1 GSTT2 CPEB4 AGXT CA3	7.85e-08	150	107	7	954ca50b36dadaab625ab011aedbf550de2e566f
ToppCell	droplet-Liver-LIVER_HEP-30m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD18 AMDHD1 ANGPTL1 GSTT2 CPEB4 AGXT CA3	7.85e-08	150	107	7	c2fcdd62ec85cbf9783a525cd7556e16a1e55cd8
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 DUOX1 FASN SCD WIF1 FAM20A CA2	3.52e-07	187	107	7	7c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCell	ASK440-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DUOX1 FASN SCD ASPH WIF1 FAM20A CA2	5.00e-07	197	107	7	08d5bbeb77a4152af1c783bc958afcae24667767
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_2-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ITPR3 DUOX1 FASN ASPH WIF1 FAM20A CA2	5.17e-07	198	107	7	19eefd05573fbaed654af52bf0f8a26092b8b229
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PAPPA2 AMDHD1 SCD5 ANGPTL1 ROBO3 FAM20A	6.14e-07	126	107	6	9b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	AMDHD1 ADGRG1 ADCY7 EFNB3 DAPP1 ABCD2	2.22e-06	157	107	6	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ITPR3 DUOX1 FASN SCD ASPH CA2	4.72e-06	179	107	6	466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ITPR3 DUOX1 FASN SCD ASPH CA2	4.72e-06	179	107	6	f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR2 CYP11A1 XPNPEP2 FKTN SCD CPT1C	5.03e-06	181	107	6	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR2 CYP11A1 XPNPEP2 FKTN SCD CPT1C	5.03e-06	181	107	6	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 GAL3ST4 SCD5 ZHX2	5.20e-06	182	107	6	a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 GAL3ST4 SCD5 ZHX2	5.20e-06	182	107	6	831b5ce46b41efe01c4db6016c2f43148611373d
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ITPR3 DUOX1 FASN SCD WIF1 CA2	5.53e-06	184	107	6	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLT8D2 CA13 SSPOP SYTL5 CA2 CA3	5.53e-06	184	107	6	ae0a77e3e520a246b17776bb19503519636b02ee
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ITPR3 DUOX1 FASN SCD WIF1 CA2	5.53e-06	184	107	6	2a8338e94937686a148b5433515700ca0f674058
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 GAL3ST4 SCD5 ZHX2	5.71e-06	185	107	6	2e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 GAL3ST4 SCD5 ZHX2	5.71e-06	185	107	6	7aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 DUOX1 FASN SCD WIF1 FAM20A	6.45e-06	189	107	6	da014519d6eb21bc2dc2ed65eafe638b42a068ed
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIP1R ADGRG1 ZHX2 SCD ZFHX3 CA2	6.45e-06	189	107	6	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.27e-06	193	107	6	8646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCell	(7)_Epithelial_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.49e-06	194	107	6	413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCell	AT2\|World / shred by cell class for parenchyma	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.49e-06	194	107	6	e773f5ef3abce7113a6b7cc7cbe68de873d4a17f
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.71e-06	195	107	6	6617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.71e-06	195	107	6	6867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.71e-06	195	107	6	fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell	390C-Epithelial_cells-Epithelial-C_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 FASN SCD WIF1 FAM20A CA2	7.71e-06	195	107	6	d0608db4a61576e67f4a3a52e1f84d788a1dea85
ToppCell	390C-Epithelial_cells-Epithelial-C_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 FASN SCD WIF1 FAM20A CA2	7.71e-06	195	107	6	bdfe486d32cb598950c1a5f5cdab40302c8f0f99
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.71e-06	195	107	6	3e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.71e-06	195	107	6	955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCell	3'-Parenchyma_lung-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.71e-06	195	107	6	eec187c087e432417bc346c5d3ead72f58bf3215
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 GRIN2C SCD5 FASN SBF1 CNTFR	7.94e-06	196	107	6	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.94e-06	196	107	6	b1abecc0aafc09ca70a5fde624f2a998c4aa3341
ToppCell	cellseq-Epithelial-Epithelial_Alveolar\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITPR3 DUOX1 FASN SCD WIF1 CA2	7.94e-06	196	107	6	a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ITPR3 DUOX1 FASN SCD ASPH WIF1	8.17e-06	197	107	6	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	390C-Epithelial_cells\|390C / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 FASN SCD WIF1 FAM20A CA2	8.17e-06	197	107	6	78554b26b04752e7cd80402c93a3a491560e8f5f
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ITPR3 DUOX1 FASN SCD ASPH WIF1	8.17e-06	197	107	6	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 SCD5 FASN EFNB3 SBF1 SCD	8.41e-06	198	107	6	43a2ce64fa309bac89a44ea320e87ae2cc39f782
ToppCell	ASK428-Epithelial-Type_2\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	DUOX1 FASN SCD ASPH WIF1 FAM20A	8.41e-06	198	107	6	ec0d1801363adb70c6a26655b79d12b438c7417d
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ITPR3 DUOX1 FASN SCD WIF1 CA2	8.66e-06	199	107	6	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_alveolar\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 FASN SCD WIF1 FAM20A CA2	8.66e-06	199	107	6	7ebd89dff457f57a549eecee288c7a4b515b4018
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS3 ANGPTL1 CILP2 WIF1 ZFHX3 CNTFR	8.66e-06	199	107	6	edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT2\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 FASN SCD WIF1 FAM20A CA2	8.66e-06	199	107	6	fa5ddba3ac1ebe712cd4cdc3f20339f7c715d039
ToppCell	Biopsy_Control_(H.)-Epithelial-AT2\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ITPR3 DUOX1 FASN SCD WIF1 CA2	8.66e-06	199	107	6	5323d49d3be980605b3e609b7f03bddba6e50e8a
ToppCell	Biopsy_IPF-Epithelial-AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	ITPR3 DUOX1 FASN SCD WIF1 CA2	8.66e-06	199	107	6	c841d475703d3489161fb7904526bd7563d5fb0f
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ITPR3 DUOX1 FASN SCD WIF1 CA2	8.91e-06	200	107	6	acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT2-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ITPR3 DUOX1 FASN SCD WIF1 CA2	8.91e-06	200	107	6	ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ITPR3 DUOX1 FASN SCD WIF1 CA2	8.91e-06	200	107	6	eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	PAPPA2 GSTT2B EFNB3 SYTL4 FER1L5	1.56e-05	130	107	5	3709d17044d48b120effd8ba4104ca81c49d7e19
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WSCD1 AMDHD1 PRDM1 ANKRD44 SYTL5	1.95e-05	136	107	5	e3a2425ba5ef538dbacab1479e682837ae42a888
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WSCD1 AMDHD1 PRDM1 ANKRD44 SYTL5	3.53e-05	154	107	5	a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2C EFNB3 PIM1 DAPP1 ROBO3	4.24e-05	160	107	5	237430af14830b38e58da8a4224036e5c6b71c5b
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DSP ADGRG1 SCD5 FASN SCD	4.50e-05	162	107	5	06f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DSP ADGRG1 SCD5 FASN SCD	4.50e-05	162	107	5	d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMDHD1 SLC3A1 FASN AGXT CA3	4.77e-05	164	107	5	90afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP2 SLC3A1 CILP2 WIF1 DAPP1	5.98e-05	172	107	5	3ffe721f62c0d20c1d765ecb15ed4e1aa88099f7
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP2 SLC3A1 CILP2 WIF1 DAPP1	5.98e-05	172	107	5	2bbe3f601a56577d200aa7ba7031f7c19b988cc1
ToppCell	Lymphoid-Lymphoid-B_cells_(cycle)\|Lymphoid / shred on cell class and cell subclass (v4)	VHL IARS1 CA13 CELSR3 DNMT1	5.98e-05	172	107	5	f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NPR2 SCD5 PRDM1 HECW2 ABCD2	6.31e-05	174	107	5	94575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NPR2 SCD5 PRDM1 HECW2 ABCD2	6.31e-05	174	107	5	40c81ab36d7931e271e20d7d56fed32463c75f41
ToppCell	droplet-Heart-nan-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCD5 FASN SCD CNTFR CA3	6.31e-05	174	107	5	cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCell	BAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NPR2 SCD5 PRDM1 HECW2 ABCD2	6.31e-05	174	107	5	b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDH23 SSPOP PRDM1 L3MBTL1 PIM1	6.84e-05	177	107	5	41cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP11A1 ADGRG1 HECW2 ASPH DAPP1	6.84e-05	177	107	5	c1f838e425ebb04482829b1957e3c1347127e6de
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSPOP GGCX PRDM1 EFNB3 FAM20A	7.03e-05	178	107	5	b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	DUOX1 FASN ASPH WIF1 FAM20A	7.41e-05	180	107	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP11A1 ADGRG1 PGLYRP2 HECW2 DAPP1	7.41e-05	180	107	5	41e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCell	normal_Lung-Myeloid_cells-CD207+CD1a+_LCs\|normal_Lung / Location, Cell class and cell subclass	DSP GPR84 SPAG9 L3MBTL1 DAPP1	7.61e-05	181	107	5	b55dbcfae8c92d322071906831489830a22239b9
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PAPPA2 GLT8D2 CYP11A1 GAL3ST4 CILP2	7.81e-05	182	107	5	0e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KIF13B NAALADL1 ADGRG1 KIR3DX1 ROBO3	7.81e-05	182	107	5	c6172aca2475bf0948a78e39f0dae6388504a915
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 SCD5 ZHX2	7.81e-05	182	107	5	8a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 SCD5 ZHX2	7.81e-05	182	107	5	3cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 SCD5 ZHX2	7.81e-05	182	107	5	5d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 SCD5 ZHX2	7.81e-05	182	107	5	e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 ITPR3 SYTL5 CA2 CA3	8.01e-05	183	107	5	f8b636391f752e379a5c5575fd898bdf0907a3b8
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	NPR2 WNT2B PPP1R15A KIR3DX1	8.15e-05	95	107	4	3d6b97576ce4e7a3e495cbc7246ea8c0b2a386f7
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PAPPA2 GLT8D2 ANGPTL1 WIF1 CNTFR	8.43e-05	185	107	5	7b1c5d99bd7a6e148524029758cee244a17f5d09
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 SCD5 ZHX2	8.43e-05	185	107	5	efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIP1R ADGRG1 ZHX2 SCD CA2	8.43e-05	185	107	5	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PAPPA2 GLT8D2 ANGPTL1 WIF1 CNTFR	8.43e-05	185	107	5	e9033a03d574956cf3ae228740b3166e40a6397f
ToppCell	AT2_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ITPR3 WIF1 FAM20A CA2 PCYOX1	8.43e-05	185	107	5	3b3268e3f99121124e33086cac88479808d31630
ToppCell	PND01-03-samps-Epithelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DSP ADGRG1 SCD5 FASN SCD	8.43e-05	185	107	5	2b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	WSCD1 HIP1R ADGRG1 SCD5 ZHX2	8.43e-05	185	107	5	fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PAPPA2 GLT8D2 ANGPTL1 WIF1 CNTFR	8.43e-05	185	107	5	578f12c6b2e33d09598dc8e022a20c8555d1325c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLT8D2 CA13 SYTL5 CA2 CA3	8.65e-05	186	107	5	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 FASN SCD WIF1 CA2	8.87e-05	187	107	5	11670a85db87cbb3e78022a589632173604b0940
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	SPAG9 FASN SCD WIF1 CA2	8.87e-05	187	107	5	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DSP ADGRG1 SCD5 FASN SCD	8.87e-05	187	107	5	23fe3cdd6cc9b067086a8392d104186d300298ea
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 FASN SCD WIF1 CA2	8.87e-05	187	107	5	0277d4e54bd4d48f30241c2951a569209423fee8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLT8D2 CA13 SYTL5 CA2 CA3	9.09e-05	188	107	5	8268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLT8D2 CA13 SYTL5 CA2 CA3	9.09e-05	188	107	5	4544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	CDH23 FASN SCD ASPH ABCD2	9.09e-05	188	107	5	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLT8D2 CA13 SYTL5 CA2 CA3	9.09e-05	188	107	5	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 FASN SCD WIF1 CA2	9.32e-05	189	107	5	6f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell	Control-Myeloid-MoAM1\|Control / Disease group,lineage and cell class （2021.01.30）	GPR84 GAL3ST4 SSPOP PRDM1 FAM20A	9.32e-05	189	107	5	55d5c2fb9e6ab556d42c83a1e985ee66e4cf9dba
Drug	AC1L9LQQ	CA13 SCD5 SLC9A3 SCD CA2 CA3	2.64e-07	57	106	6	CID000448224
Drug	chlorzolamide	CA13 AGXT CA2 CA3	3.07e-07	13	106	4	CID000165323
Drug	Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A	VHL WSCD1 ADGRG1 GRIN2C PRDM1 CACTIN SLC9A3 EFNB3 AGXT	3.61e-07	197	106	9	5605_UP
Drug	sterculic acid	SCD5 FASN SCD	3.39e-06	7	106	3	CID000012921
Drug	potassium cyanate	CA13 AGXT CA2 CA3	4.39e-06	24	106	4	CID011378442
Drug	aminozolamide	CA13 CA2 CA3	5.40e-06	8	106	3	CID000093505
Drug	L-662,583	CA13 CA2 CA3	5.40e-06	8	106	3	CID003082977
Drug	L-643,799	CA13 CA2 CA3	5.40e-06	8	106	3	CID000121595
Drug	sezolamide	CA13 CA2 CA3	5.40e-06	8	106	3	CID000060692
Drug	methazolamide	CA13 CELSR3 CA2 CA3	6.13e-06	26	106	4	CID000004100
Drug	1gaf	NPR2 CA13 SPAG9 CA2 CA3	6.29e-06	56	106	5	CID000444283
Drug	qassa	CA13 CA2 CA3	8.07e-06	9	106	3	CID003082191
Drug	6-hydroxyethoxzolamide	CA13 CA2 CA3	8.07e-06	9	106	3	CID000094706
Drug	benzolamide	CA13 SLC9A3 CA2 CA3	8.34e-06	28	106	4	CID000018794
Drug	AC1L1FF5	PTGES2 SCD5 BCO1 FASN SYTL4 SCD CPT1C	8.92e-06	157	106	7	CID000003209
Drug	Prontosil	CA13 CA2 CA3	1.15e-05	10	106	3	CID000066895
Drug	metanilamide	CA13 CA2 CA3	1.15e-05	10	106	3	CID000007377
Drug	1,3-benzenedisulfonamide	CA13 CA2 CA3	1.15e-05	10	106	3	CID003090044
Drug	carbamoyl phosphate	AMDHD1 CA13 SBF1 KLHDC3 CA2 CA3	1.49e-05	113	106	6	CID000000278
Drug	Cl 13850	CA13 CA2 CA3	1.58e-05	11	106	3	CID000159459
Drug	cobalt phosphate	CA13 CA2 CA3	1.58e-05	11	106	3	CID000061615
Drug	Tio-urasin	CA13 CA2 CA3	1.58e-05	11	106	3	CID000084724
Drug	hydroflumethiazide	CA13 CA2 CA3	2.09e-05	12	106	3	CID000003647
Drug	sulfamidochrysoidine	CA2 CA3	2.15e-05	2	106	2	ctd:C003359
Drug	dorzolamide	CA2 CA3	2.15e-05	2	106	2	ctd:C062765
Drug	chlorthalidone	CA13 ADCY7 CA2 CA3	2.33e-05	36	106	4	CID000002732
Drug	Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; PC3; HT_HG-U133A	PPP1R15A PRDM1 SLC9A3 EFNB3 PIM1 WIF1 AGXT	2.67e-05	186	106	7	3768_UP
Drug	mafenide acetate	CA13 CA2 CA3	2.71e-05	13	106	3	CID000003998
Drug	Fg 400	CA13 CA2 CA3	2.71e-05	13	106	3	CID000012443
Drug	cobalt;sulfide	CA13 CA2 CA3	3.44e-05	14	106	3	CID000159453
Drug	Apomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; PC3; HG-U133A	WSCD1 KIF13B TMEM53 GAL3ST4 CACTIN DZANK1 SBF1	3.74e-05	196	106	7	1923_UP
Drug	Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; PC3; HT_HG-U133A	PAPPA2 NPR2 TMEM53 SCD5 SLC3A1 L3MBTL1 CELSR3	3.74e-05	196	106	7	3726_DN
Drug	Amoxapine [14028-44-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A	PAPPA2 ABHD18 ADCY7 BCO1 EFNB3 CELSR3 SCML1	3.86e-05	197	106	7	1513_UP
Drug	Flucytosine [2022-85-7]; Down 200; 31uM; PC3; HT_HG-U133A	KIF13B GGCX SLC3A1 EFNB3 PIM1 SGSM2 DAPP1	4.25e-05	200	106	7	6690_DN
Drug	AC1L1F9Q	PTGES2 SCD5 BCO1 FASN SCD CPT1C ABCD2	4.39e-05	201	106	7	CID000003144
Drug	ethacrynic acid	KIF13B CA13 ADCY7 GSTT2 CA2 CA3	4.61e-05	138	106	6	CID000003278
Drug	Bicarbonates	SLC9A3 CA2 CA3	5.26e-05	16	106	3	ctd:D001639
Drug	eicosa-8,11,14-trienoic acid	PTGES2 ADAMTS3 SCD5 BCO1 SCD	5.73e-05	88	106	5	CID000003011
Drug	metolazone	CA13 CA2 CA3	6.36e-05	17	106	3	CID000004170
Drug	Dichlorphenamide	CA2 CA3	6.42e-05	3	106	2	ctd:D004005
Drug	I2-15	SCD5 SCD	6.42e-05	3	106	2	CID000013388
Drug	Benzolamide	CA2 CA3	6.42e-05	3	106	2	ctd:D001574
Drug	Ethoxzolamide	CA2 CA3	6.42e-05	3	106	2	ctd:D005016
Drug	betaxolol	CA13 ADCY7 CA2 CA3	7.38e-05	48	106	4	CID000002369
Drug	apraclonidine	CA13 CA2 CA3	7.61e-05	18	106	3	CID000002216
Drug	1-methylcyclopentanecarboxylic acid	CA13 PSMD2 SLC3A1 CA2 CA3	8.26e-05	95	106	5	CID000138436
Drug	sulthiame	CA13 CA2 CA3	9.00e-05	19	106	3	CID000005356
Drug	racemic timolol	CA13 ADCY7 CA2 CA3	9.37e-05	51	106	4	CID000005478
Drug	indapamide	CA13 ADCY7 CA2 CA3	1.09e-04	53	106	4	CID000003702
Drug	oxygen	VHL CYP11A1 GGCX BCO1 DUOX1 SCD ASPH AGXT CA2 PCYOX1	1.14e-04	499	106	10	CID000000977
Drug	AC1LCVB4	CA13 CA2 CA3	1.23e-04	21	106	3	CID000656627
Drug	N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide	CA2 CA3	1.28e-04	4	106	2	ctd:C439829
Drug	D-GDH	PTGES2 AGXT	1.28e-04	4	106	2	CID000128097
Drug	9-hexadecenal	SCD5 SCD	1.28e-04	4	106	2	CID000092066
Drug	I-7B	CA13 CA2	1.28e-04	4	106	2	CID000067136
Drug	AABSSN	CA13 CA2 CA3	1.42e-04	22	106	3	CID005464134
Drug	tiadenol	SCD5 GSTT2 SCD CPT1C	1.45e-04	57	106	4	CID000023403
Drug	dichlorphenamide	CA13 CA2 CA3	1.62e-04	23	106	3	CID000003038
Drug	2,2,5,7,8-pentamethyl-1-hydroxychroman	AMDHD1 XPNPEP2 GRIN2C PPP1R15A ABCD2 CA2 CA3	1.80e-04	252	106	7	ctd:C029141
Drug	Fe(III	VHL IARS1 ACP2 AMDHD1 PSMD2 SCD5 ITPR3 BCO1 KLHDC3 SCD	2.06e-04	537	106	10	CID000023925
Drug	pinolenic acid	SCD5 SCD AGXT	2.09e-04	25	106	3	CID005312493
Drug	1-penten-3-ol	SCD5 SCD	2.13e-04	5	106	2	CID000012020
Drug	methyl sterculate	SCD5 SCD	2.13e-04	5	106	2	CID000115261
Drug	16-methylprogesterone	SCD5 SCD	2.13e-04	5	106	2	CID000134874
Drug	brinzolamide	CA2 CA3	2.13e-04	5	106	2	ctd:C111827
Disease	Charcot-Marie-Tooth disease (biomarker_via_orthology)	GSTT2B GSTT2	1.16e-05	2	101	2	DOID:10595 (biomarker_via_orthology)
Disease	carbonic anhydrase 1 measurement	CA13 CA3	3.47e-05	3	101	2	EFO_0020227
Disease	Prostatic Intraepithelial Neoplasias	PIM1 DNMT1	6.25e-04	11	101	2	C0282612
Disease	lung adenocarcinoma (is_implicated_in)	CHD4 PRDM1 ZFHX3	6.40e-04	49	101	3	DOID:3910 (is_implicated_in)
Disease	3-formylindole measurement	GSTT2B GSTT2	8.83e-04	13	101	2	EFO_0801025
Disease	restrictive cardiomyopathy (implicated_via_orthology)	SCD5 SCD	8.83e-04	13	101	2	DOID:397 (implicated_via_orthology)
Disease	Premature atrial contractions	SCD5 ANKRD44 DNMT1	8.97e-04	55	101	3	HP_0006699
Disease	serum albumin measurement	PILRB CYP11A1 SPAG9 PRDM1 CILP2 CPT1C CPEB4 XKR5	9.88e-04	592	101	8	EFO_0004535
Disease	Pneumoconiosis	CDH23 CA3	1.03e-03	14	101	2	C0032273
Disease	Bagassosis	CDH23 CA3	1.03e-03	14	101	2	C0004681
Disease	intracerebral hemorrhage	CUX2 ADGRG1	1.35e-03	16	101	2	EFO_0005669
Disease	hypertrophic cardiomyopathy (is_marker_for)	DSP DNMT1	1.53e-03	17	101	2	DOID:11984 (is_marker_for)
Disease	mean arterial pressure	CUX2 WNT2B SCD CPEB4 AGXT ZFHX3 DNMT1	1.66e-03	499	101	7	EFO_0006340
Disease	colorectal cancer (is_marker_for)	CHD4 PRDM1 FASN ZFHX3	2.11e-03	157	101	4	DOID:9256 (is_marker_for)
Disease	smoking status measurement, diastolic blood pressure	WSCD1 WNT2B AGXT FER1L5	2.21e-03	159	101	4	EFO_0006336, EFO_0006527

Protein segments in the cluster

Peptide	Gene	Start	Entry
AGEKALYHAGLFLWH	TTC21B	106	Q7Z4L5
LYHAGLFLWHIGRHD	TTC21B	111	Q7Z4L5
GPYRLRQFHLHWGSS	CA3	86	P07451
YVHLWEALGHHGRSR	ANKLE1	496	Q8NAG6
YWGFRATDHHVQGRD	C9orf129	126	Q5T035
RHNHWAGLYGRLEWD	DNMT1	1506	P26358
HTHLLQFDGEGGWRF	ABCD2	671	Q9UBJ2
IHLAGTGDHHYWRRR	ABHD18	111	Q0P651
GRLGDLWDYHQHRYL	IBA57	211	Q5T440
AHSNLNGVWYRGGHY	ANGPTL1	446	O95841
LHGHFNWTARAALLY	NPR2	156	P20594
HKRGHFASVWQRSLY	ASPH	551	Q12797
TGSYRLRQVHLHWGS	CA13	86	Q8N1Q1
WGAARPFAHLNHRES	ADCY7	491	P51828
DHHWASDRGLLSRPY	CUX2	786	O14529
CGGQRSPWHADDRHY	DENND6B	101	Q8NEG7
RVWYRILHGNHGNNF	CDH23	1136	Q9H251
EWRPVHYAAFHGRLG	ANKRD42	131	Q8N9B4
GAGHWNGLYRFKHLA	ITPR3	296	Q14573
HRGVDGQWDLSNYHL	SPAG9	1026	O60271
RSFRGFWLTHHLYIL	DUOX1	1216	Q9NRD9
DNHHEWFRFSGRILG	HECW2	1301	Q9P2P5
WRNNTEYRGGYHDNH	HECW2	1461	Q9P2P5
YRLSGSFAHQGLWRY	LIM2	31	P55344
AHCSGSRYWVRLGEH	KLK12	61	Q9UKR0
GWTALHRSIFYGHID	IBTK	86	Q9P2D0
NAALLAYHRWNGHTD	PCYOX1	476	Q9UHG3
RIKIHFDGWSHGYDF	L3MBTL1	546	Q9Y468
HAAQRFLSRYGWSGV	MMP21	51	Q8N119
GPHNRLYHFLLGAWS	PGLYRP2	61	Q96PD5
FFSGWVQHRRGSVHL	PRAMEF18	166	Q5VWM3
RHLGWNPDARYSEHF	GLT8D2	291	Q9H1C3
HYAAARGHATWLSEL	ANKRD44	741	Q8N8A2
RGDHYARNLLWFDFG	GAL3ST4	201	Q96RP7
HEYLGWHADCIRGTF	GSTT2B	96	P0CG30
YLHLHWRTGATFCRV	GPR84	81	Q9NQS5
DQYHLFRHGVAHGQW	KIR3DX1	251	Q9H7L2
YGWEFHDGLSFGRQH	MOGS	146	Q13724
KEWLSFGHRFSHRGA	SBF1	1456	O95248
HWELGQALRQRYHGF	ACP2	76	P11117
GHYFRGHLGTLVFWS	PAPPA2	416	Q9BXP8
YAHALLAGRGHDRWF	CPT1C	436	Q8TCG5
AAFHRYHWSRCSGQE	ADAMTS3	431	O15072
GDLWGHLHDRYGQLV	HIP1R	116	O75146
RVAKNQYGWHGRHSL	E2F7	201	Q96AV8
FCWANIHSRAGREFH	CPEB2	556	Q7Z5Q1
HRGIHNSIGDYRWQL	DSP	221	P15924
HEYLGWHADCIRGTF	GSTT2	96	P0CG29
LGHSGLYACFHRDSW	CNTFR	81	P26992
QDLGWYHGNLTRHAA	DAPP1	31	Q9UN19
GLYHFCLYWNRHAGR	ADGRG1	86	Q9Y653
WELRQKGSVHHDYRG	CYP11A1	286	P05108
FHERSGNYLWHGHLR	FKTN	176	O75072
SSRWEHLIYQFGGHH	AMDHD1	396	Q96NU7
GYNARLNRHFHDLWK	KLHDC3	256	Q9BQ90
REWEYSHRHGFRCQF	CACTIN	726	Q8WUQ7
YCWAAIHSRAGREFH	CPEB4	696	Q17RY0
YHSNLFRGQDAWDPH	CELSR3	2346	Q9NYQ7
GRGYWRRQLDHISAH	DZANK1	476	Q9NVP4
YRDGAWGAFRHFLLE	FASN	1506	P49327
RRHDYWLLAGIINHG	CHD4	1731	Q14839
SPNLWGHEFRSHHDY	EFNB3	121	Q15768
SHPDQRAHFRGWGYR	PPP1R15A	471	O75807
HSLDGFRHQALWDRY	FIBP	336	O43427
HRYHGRSAAVWSLGI	PIM1	216	P11309
LHHGDRILWGNNHFF	KIF13B	526	Q9NQT8
TLQFSVWHHGRFGRN	SYTL4	441	Q96C24
WHYDRFGRNSFLGEV	SYTL5	496	Q8TDW5
YSGGLGRQFFHLHWH	TAS2R41	76	P59536
NSWRQHREAAAYLHG	AGXT	286	P21549
RFHARSLWTNHKRYG	SCML1	91	Q9UN30
QFSSNGLHWHDYRDL	SSPOP	2156	A2VEC9
IHYHSLTGEADFNWR	FER1L5	1766	A0AVI2
LASWGHEYVRHLAGE	PSMD2	151	Q13200
AIGLYHACRGWGRHT	SLC5A6	41	Q9Y289
GAHLNYHRSLISWGI	SLC25A51	271	Q9H1U9
WVQFHLGINRHGLYS	FAM20A	161	Q96MK3
GQIGHNYLRDKWSHF	SLC9A3	496	P48764
VSRAFYGWLAHCRHL	SGSM2	496	O43147
NRGWFCHLRNDSHYV	SLC3A1	566	Q07837
AGAHRLWSHRSYRAK	SCD5	91	Q86SK9
LGGALGLYHTARWHL	PTGES2	66	Q9H7Z7
WRIYSRGELHHFIDG	PRDM1	136	O75626
YAHQSGFHVDRRFGW	IARS1	71	P41252
GAHLNYHRSLISWGI	SLC25A52	271	Q3SY17
APFLAAFRADGRWHH	ADGRD2	196	Q7Z7M1
RYNHWFDGLALLHSF	BCO1	46	Q9HAY6
GTYRLIQFHFHWGSL	CA2	86	P00918
WFHNGTLLDRRAHGY	CILP2	326	Q8IUL8
ASYHGNLAVLYHRWG	TMTC4	686	Q5T4D3
WIHARHLAGYRQQDA	USP27X	151	A6NNY8
ANHYWSVDGLLNAHR	GGCX	176	P38435
WDIVRHYGTHHFRGS	TBL3	136	Q12788
GRYEIRSDHSLWIGH	ROBO3	301	Q96MS0
HTHFYDRLQDAGSRW	TMEM53	196	Q6P2H8
SYRGHLWLFRDAGTH	VHL	111	P40337
GWHGRHCNKRYEASL	WIF1	331	Q9Y5W5
HNSRRGFFFSHVGWL	SCD	171	O00767
WRRGHFHGQSFYSTR	PILRB	71	Q9UKJ0
WFSDHRYRCQRGIVH	ZHX2	486	Q9Y6X8
LALGAFLNHWRNRFH	TOMM40L	286	Q969M1
DGRQRWGHRILHYSF	XKR3	336	Q5GH77
FARRALWDAGLNYGH	XPNPEP2	506	O43895
WARHLIEHATGFYTG	WSCD1	366	Q658N2
ALSYLWFRADGHPGH	XKR5	51	Q6UX68
YTRGRHHDQRGDFDW	WNT2B	171	Q93097
DGSSGRLQLWHHDYL	TTC31	66	Q49AM3
RSRHWHEAKRAGYNL	ZFHX3	2731	Q15911
RYVLYGNHRDSWVHG	NAALADL1	361	Q9UQQ1
LALGAHSYWRQHGTL	GRIN2C	296	Q14957