Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9C LGALS9B LGALS9

6.49e-077543GO:0048030
GeneOntologyMolecularFunctiongalactoside binding

LGALS9C LGALS9B LGALS9

1.55e-069543GO:0016936
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS9C LGALS9B LGALS9

2.06e-0520543GO:0070492
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase activity

CDK16 CDK2 CDK3

7.21e-0530543GO:0004693
GeneOntologyMolecularFunctioncyclin-dependent protein kinase activity

CDK16 CDK2 CDK3

7.21e-0530543GO:0097472
GeneOntologyMolecularFunctionprotein kinase regulator activity

LGALS9C LGALS9B ELP3 LGALS9 PRKRA

6.65e-04259545GO:0019887
GeneOntologyMolecularFunctionprotein kinase activator activity

LGALS9C LGALS9B LGALS9 PRKRA

7.05e-04149544GO:0030295
GeneOntologyMolecularFunctionkinase activator activity

LGALS9C LGALS9B LGALS9 PRKRA

8.98e-04159544GO:0019209
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9A3 SLC24A4

1.19e-0319542GO:0022821
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

LGALS9C LGALS9B LGALS9

1.23e-0378543GO:0043539
GeneOntologyMolecularFunctionkinase regulator activity

LGALS9C LGALS9B ELP3 LGALS9 PRKRA

1.38e-03305545GO:0019207
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

6.40e-084533GO:0043322
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B CARD11 LGALS9

7.60e-0728534GO:2000561
GeneOntologyBiologicalProcessregulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

8.89e-078533GO:0043321
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B CARD11 LGALS9

1.01e-0630534GO:0035739
GeneOntologyBiologicalProcessregulation of T cell differentiation in thymus

LGALS9C LGALS9B ADAM8 LGALS9

2.41e-0637534GO:0033081
GeneOntologyBiologicalProcesspositive regulation of T cell migration

LGALS9C LGALS9B ADAM8 LGALS9

3.67e-0641534GO:2000406
GeneOntologyBiologicalProcesspositive regulation of mononuclear cell migration

LGALS9C LGALS9B SERPINE1 ADAM8 LGALS9

7.00e-06104535GO:0071677
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

7.13e-0615533GO:2000562
GeneOntologyBiologicalProcessnegative regulation of natural killer cell activation

LGALS9C LGALS9B LGALS9

7.13e-0615533GO:0032815
GeneOntologyBiologicalProcesspositive regulation of lymphocyte migration

LGALS9C LGALS9B ADAM8 LGALS9

7.55e-0649534GO:2000403
GeneOntologyBiologicalProcesspositive regulation of T cell activation

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

8.95e-06290537GO:0050870
GeneOntologyBiologicalProcessregulation of alpha-beta T cell proliferation

LGALS9C LGALS9B CARD11 LGALS9

1.04e-0553534GO:0046640
GeneOntologyBiologicalProcesslymphocyte chemotaxis

LGALS9C LGALS9B ADAM8 LGALS9

1.04e-0553534GO:0048247
GeneOntologyBiologicalProcessnegative regulation of leukocyte degranulation

LGALS9C LGALS9B LGALS9

1.06e-0517533GO:0043301
GeneOntologyBiologicalProcessT cell differentiation in thymus

LGALS9C LGALS9B CARD11 ADAM8 LGALS9

1.10e-05114535GO:0033077
GeneOntologyBiologicalProcessnatural killer cell degranulation

LGALS9C LGALS9B LGALS9

1.27e-0518533GO:0043320
GeneOntologyBiologicalProcessregulation of T cell migration

LGALS9C LGALS9B ADAM8 LGALS9

1.29e-0556534GO:2000404
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

LGALS9C CDH22 HMCN2 CELSR3 LGALS9B MYPN LGALS9

1.47e-05313537GO:0098742
GeneOntologyBiologicalProcesspositive regulation of cell adhesion

LGALS9C LGALS9B RELL2 BTNL2 KDR CARD11 ADAM8 PNP LGALS9

1.50e-05579539GO:0045785
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

1.51e-0519533GO:0046642
GeneOntologyBiologicalProcesspositive regulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

1.51e-0519533GO:1900426
GeneOntologyBiologicalProcessalpha-beta T cell proliferation

LGALS9C LGALS9B CARD11 LGALS9

1.59e-0559534GO:0046633
GeneOntologyBiologicalProcesspositive regulation of leukocyte cell-cell adhesion

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

1.59e-05317537GO:1903039
GeneOntologyBiologicalProcesspositive regulation of cytokine production

LGALS9C LGALS9B ABCC8 BTNL2 SERPINE1 CARD11 ADAM8 PNP LGALS9

1.65e-05586539GO:0001819
GeneOntologyBiologicalProcessregulation of cell development

LGALS9C ZBTB7A LGALS9B ABCC8 LRP2 KDR CARD11 ADAM8 NOS1 PNP LGALS9 SYNGAP1

1.66e-0510955312GO:0060284
GeneOntologyBiologicalProcessregulation of T cell chemotaxis

LGALS9C LGALS9B LGALS9

1.77e-0520533GO:0010819
GeneOntologyBiologicalProcessregulation of cell adhesion

LGALS9C LGALS9B RELL2 BTNL2 SERPINE1 KDR CARD11 ADAM8 PNP EPHA5 LGALS9

1.92e-059275311GO:0030155
GeneOntologyBiologicalProcessregulation of natural killer cell differentiation

LGALS9C LGALS9B LGALS9

2.06e-0521533GO:0032823
GeneOntologyBiologicalProcessregulation of T cell differentiation

LGALS9C LGALS9B CARD11 ADAM8 PNP LGALS9

2.42e-05226536GO:0045580
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor superfamily cytokine production

LGALS9C LGALS9B ABCC8 ADAM8 LGALS9

2.67e-05137535GO:1903557
GeneOntologyBiologicalProcessregulation of alpha-beta T cell activation

LGALS9C LGALS9B CARD11 PNP LGALS9

3.06e-05141535GO:0046634
GeneOntologyBiologicalProcessregulation of T cell proliferation

LGALS9C LGALS9B BTNL2 CARD11 PNP LGALS9

3.08e-05236536GO:0042129
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation

LGALS9C LGALS9B ADAM8 PNP LGALS9

3.39e-05144535GO:0045582
GeneOntologyBiologicalProcessregulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

3.99e-0526533GO:1900424
GeneOntologyBiologicalProcessregulation of lymphocyte migration

LGALS9C LGALS9B ADAM8 LGALS9

4.58e-0577534GO:2000401
GeneOntologyBiologicalProcesspositive regulation of lymphocyte activation

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

5.50e-05385537GO:0051251
GeneOntologyBiologicalProcessT cell migration

LGALS9C LGALS9B ADAM8 LGALS9

5.58e-0581534GO:0072678
GeneOntologyBiologicalProcessregulation of macrophage activation

LGALS9C LGALS9B ADGRF5 LGALS9

5.58e-0581534GO:0043030
GeneOntologyBiologicalProcessregulation of mononuclear cell migration

LGALS9C LGALS9B SERPINE1 ADAM8 LGALS9

5.61e-05160535GO:0071675
GeneOntologyBiologicalProcesspositive regulation of cell-cell adhesion

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

5.87e-05389537GO:0022409
GeneOntologyBiologicalProcesspositive regulation of lymphocyte differentiation

LGALS9C LGALS9B ADAM8 PNP LGALS9

5.95e-05162535GO:0045621
GeneOntologyBiologicalProcessregulation of lymphocyte differentiation

LGALS9C LGALS9B CARD11 ADAM8 PNP LGALS9

6.01e-05266536GO:0045619
GeneOntologyBiologicalProcessreceptor clustering

LGALS9C LGALS9B LGALS9 SYNGAP1

6.14e-0583534GO:0043113
GeneOntologyBiologicalProcessregulation of lymphocyte chemotaxis

LGALS9C LGALS9B LGALS9

6.84e-0531533GO:1901623
GeneOntologyBiologicalProcesspositive regulation of regulatory T cell differentiation

LGALS9C LGALS9B LGALS9

6.84e-0531533GO:0045591
GeneOntologyBiologicalProcessnegative regulation of regulated secretory pathway

LGALS9C LGALS9B LGALS9

7.54e-0532533GO:1903306
GeneOntologyBiologicalProcesscell-cell adhesion

LGALS9C CDH22 HMCN2 CELSR3 LGALS9B BTNL2 MYPN CARD11 ADAM8 PNP LGALS9

7.54e-0510775311GO:0098609
GeneOntologyBiologicalProcessT cell chemotaxis

LGALS9C LGALS9B LGALS9

8.28e-0533533GO:0010818
GeneOntologyBiologicalProcessT cell proliferation

LGALS9C LGALS9B BTNL2 CARD11 PNP LGALS9

9.31e-05288536GO:0042098
GeneOntologyBiologicalProcesspositive regulation of leukocyte migration

LGALS9C LGALS9B SERPINE1 ADAM8 LGALS9

9.53e-05179535GO:0002687
GeneOntologyBiologicalProcesspositive regulation of leukocyte activation

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

9.92e-05423537GO:0002696
GeneOntologyBiologicalProcessregulation of leukocyte differentiation

LGALS9C ZBTB7A LGALS9B CARD11 ADAM8 PNP LGALS9

1.08e-04429537GO:1902105
GeneOntologyBiologicalProcessregulation of lymphocyte proliferation

LGALS9C LGALS9B BTNL2 CARD11 PNP LGALS9

1.19e-04301536GO:0050670
GeneOntologyBiologicalProcessnatural killer cell differentiation

LGALS9C LGALS9B LGALS9

1.27e-0438533GO:0001779
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell activation

LGALS9C LGALS9B CARD11 LGALS9

1.27e-04100534GO:2000514
GeneOntologyBiologicalProcessregulation of mononuclear cell proliferation

LGALS9C LGALS9B BTNL2 CARD11 PNP LGALS9

1.30e-04306536GO:0032944
GeneOntologyBiologicalProcessexport from cell

LGALS9C CDK16 SLC24A4 LGALS9B ABCC8 MYO19 EXOC7 ADAM8 NOS1 EPHA5 LGALS9

1.38e-0411535311GO:0140352
GeneOntologyBiologicalProcessregulation of leukocyte cell-cell adhesion

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

1.40e-04447537GO:1903037
GeneOntologyBiologicalProcesspositive regulation of cell activation

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

1.44e-04449537GO:0050867
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity

LGALS9C LGALS9B LGALS9

1.48e-0440533GO:0045953
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell activation

LGALS9C LGALS9B LGALS9

1.48e-0440533GO:2000515
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immunity

LGALS9C LGALS9B LGALS9

1.59e-0441533GO:0002716
GeneOntologyBiologicalProcessregulation of T cell activation

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

1.62e-04458537GO:0050863
GeneOntologyBiologicalProcessnatural killer cell activation involved in immune response

LGALS9C LGALS9B LGALS9

1.71e-0442533GO:0002323
GeneOntologyBiologicalProcesspositive regulation of interleukin-2 production

BTNL2 CARD11 PNP

1.71e-0442533GO:0032743
GeneOntologyBiologicalProcesspositive regulation of macrophage activation

LGALS9C LGALS9B LGALS9

1.71e-0442533GO:0043032
GeneOntologyBiologicalProcesspositive regulation of SMAD protein signal transduction

LGALS9C LGALS9B LGALS9

1.84e-0443533GO:0060391
GeneOntologyBiologicalProcessmetal ion transport

CACNG7 SLC9A3 SLC24A4 ABCC8 SERPINE1 LRP2 FGF11 GRIN3A NOS1 CDK2

2.00e-0410005310GO:0030001
GeneOntologyBiologicalProcessregulation of leukocyte proliferation

LGALS9C LGALS9B BTNL2 CARD11 PNP LGALS9

2.02e-04332536GO:0070663
GeneOntologyBiologicalProcessnegative regulation of innate immune response

LGALS9C LGALS9B FAM3A LGALS9

2.10e-04114534GO:0045824
GeneOntologyBiologicalProcessnegative regulation of exocytosis

LGALS9C LGALS9B LGALS9

2.11e-0445533GO:0045920
GeneOntologyBiologicalProcessregulation of cytokine production

LGALS9C IGF2BP2 LGALS9B ABCC8 BTNL2 SERPINE1 CARD11 ADAM8 PNP LGALS9

2.16e-0410105310GO:0001817
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LGALS9C LGALS9B KDR LGALS9

2.17e-04115534GO:0090100
GeneOntologyBiologicalProcessnegative regulation of secretion by cell

LGALS9C LGALS9B ABCC8 NOS1 LGALS9

2.20e-04214535GO:1903531
GeneOntologyBiologicalProcesslymphocyte migration

LGALS9C LGALS9B ADAM8 LGALS9

2.25e-04116534GO:0072676
GeneOntologyBiologicalProcesspositive regulation of oxidoreductase activity

LGALS9C LGALS9B LGALS9

2.25e-0446533GO:0051353
GeneOntologyBiologicalProcessleukocyte cell-cell adhesion

LGALS9C LGALS9B BTNL2 CARD11 ADAM8 PNP LGALS9

2.33e-04486537GO:0007159
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated cytotoxicity

LGALS9C LGALS9B LGALS9

2.40e-0447533GO:0001911
GeneOntologyBiologicalProcessregulation of T-helper 17 type immune response

LGALS9C LGALS9B LGALS9

2.40e-0447533GO:2000316
GeneOntologyBiologicalProcesspositive regulation of interleukin-10 production

LGALS9C LGALS9B LGALS9

2.55e-0448533GO:0032733
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LGALS9C ZBTB7A LGALS9B LRP2 KDR LGALS9

2.56e-04347536GO:0090092
GeneOntologyBiologicalProcessregulation of regulatory T cell differentiation

LGALS9C LGALS9B LGALS9

2.71e-0449533GO:0045589
GeneOntologyBiologicalProcessalpha-beta T cell activation

LGALS9C LGALS9B CARD11 PNP LGALS9

2.88e-04227535GO:0046631
GeneOntologyBiologicalProcessregulation of leukocyte mediated cytotoxicity

LGALS9C LGALS9B PNP LGALS9

2.90e-04124534GO:0001910
GeneOntologyBiologicalProcesspositive regulation of T cell proliferation

BTNL2 CARD11 PNP LGALS9

2.99e-04125534GO:0042102
GeneOntologyBiologicalProcessnegative regulation of type II interferon production

LGALS9C LGALS9B LGALS9

3.06e-0451533GO:0032689
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell activation

LGALS9C LGALS9B LGALS9

3.24e-0452533GO:0046636
GeneOntologyBiologicalProcessnegative regulation of cell killing

LGALS9C LGALS9B LGALS9

3.24e-0452533GO:0031342
GeneOntologyBiologicalProcesscell chemotaxis

LGALS9C LGALS9B SERPINE1 KDR ADAM8 LGALS9

3.26e-04363536GO:0060326
GeneOntologyBiologicalProcesschemotaxis

LGALS9C LGALS9B SERPINE1 LRP2 KDR ADAM8 LGALS9

3.39e-04517537GO:0006935
GeneOntologyBiologicalProcessregulation of tumor necrosis factor superfamily cytokine production

LGALS9C LGALS9B ABCC8 ADAM8 LGALS9

3.45e-04236535GO:1903555
GeneOntologyBiologicalProcesstaxis

LGALS9C LGALS9B SERPINE1 LRP2 KDR ADAM8 LGALS9

3.47e-04519537GO:0042330
GeneOntologyBiologicalProcessregulatory T cell differentiation

LGALS9C LGALS9B LGALS9

3.62e-0454533GO:0045066
GeneOntologyBiologicalProcessregulation of T cell apoptotic process

ADAM8 PNP LGALS9

3.62e-0454533GO:0070232
GeneOntologyBiologicalProcessnegative regulation of secretion

LGALS9C LGALS9B ABCC8 NOS1 LGALS9

3.65e-04239535GO:0051048
GeneOntologyBiologicalProcessregulation of leukocyte activation

LGALS9C LGALS9B BTNL2 CARD11 ADGRF5 ADAM8 PNP LGALS9

3.67e-04694538GO:0002694
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor production

LGALS9C LGALS9B ABCC8 LGALS9

3.79e-04133534GO:0032760
GeneOntologyBiologicalProcesspositive regulation of leukocyte differentiation

LGALS9C LGALS9B ADAM8 PNP LGALS9

3.87e-04242535GO:1902107
GeneOntologyBiologicalProcesspositive regulation of hemopoiesis

LGALS9C LGALS9B ADAM8 PNP LGALS9

3.87e-04242535GO:1903708
GeneOntologyBiologicalProcessregulation of chemotaxis

LGALS9C LGALS9B SERPINE1 KDR LGALS9

3.87e-04242535GO:0050920
GeneOntologyCellularComponentexternal encapsulating structure

LGALS9C HMCN2 LGALS9B RELL2 SERPINE1 SRPX PKHD1L1 LGALS9

2.68e-04658548GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LGALS9C HMCN2 LGALS9B RELL2 SERPINE1 SRPX LGALS9

4.09e-04530547GO:0062023
GeneOntologyCellularComponentcyclin-dependent protein kinase holoenzyme complex

CDK16 CDK2 CDK3

5.27e-0461543GO:0000307
GeneOntologyCellularComponentserine/threonine protein kinase complex

CDK16 ZBTB7A CDK2 CDK3

7.23e-04157544GO:1902554
GeneOntologyCellularComponentprotein kinase complex

CDK16 ZBTB7A CDK2 CDK3

9.73e-04170544GO:1902911
MousePhenoincreased T-helper cell number

LGALS9C LGALS9B CARD11 PNP LGALS9

9.30e-0756455MP:0013763
MousePhenoabnormal T-helper cell number

LGALS9C LGALS9B GMDS CARD11 PNP LGALS9

1.62e-06114456MP:0013761
MousePhenodecreased regulatory T cell number

LGALS9C LGALS9B GMDS CARD11 LGALS9

1.82e-0664455MP:0004974
MousePhenoabnormal effector T cell number

LGALS9C LGALS9B FAM3A GMDS CARD11 PNP LGALS9

3.49e-06203457MP:0013762
MousePhenolymph node hyperplasia

LGALS9C LGALS9B CARD11 LGALS9

3.58e-0633454MP:0008102
MousePhenoabnormal T-helper cell morphology

LGALS9C LGALS9B GMDS CARD11 PNP LGALS9

7.66e-06149456MP:0013760
MousePhenoabnormal CD4-positive helper T cell morphology

LGALS9C LGALS9B CARD11 PNP LGALS9

1.65e-05100455MP:0010183
MousePhenoenhanced humoral immune response

LGALS9C LGALS9B LGALS9

2.05e-0517453MP:0020155
MousePhenoincreased T-helper 1 cell number

LGALS9C LGALS9B LGALS9

2.91e-0519453MP:0008086
MousePhenoabnormal regulatory T cell number

LGALS9C LGALS9B GMDS CARD11 LGALS9

3.24e-05115455MP:0004972
MousePhenoabnormal regulatory T cell morphology

LGALS9C LGALS9B GMDS CARD11 LGALS9

3.52e-05117455MP:0004941
MousePhenoincreased spleen germinal center size

LGALS9C LGALS9B LGALS9

5.28e-0523453MP:0008483
MousePhenoabnormal lymph node germinal center morphology

LGALS9C LGALS9B LGALS9

5.28e-0523453MP:0008522
MousePhenoabnormal T-helper 1 cell number

LGALS9C LGALS9B LGALS9

6.02e-0524453MP:0008085
MousePhenoabnormal lymph node secondary follicle morphology

LGALS9C LGALS9B LGALS9

6.82e-0525453MP:0002346
MousePhenoincreased B cell proliferation

LGALS9C LGALS9B CARD11 LGALS9

9.64e-0575454MP:0005154
MousePhenoabnormal gamma-delta T cell morphology

BTNL2 GMDS CARD11 TRAPPC9

1.12e-0478454MP:0008343
MousePhenoincreased CD4-positive, alpha-beta T cell number

LGALS9C LGALS9B GMDS CARD11 PNP LGALS9

1.14e-04241456MP:0008074
MousePhenoabnormal B cell proliferation

LGALS9C LGALS9B CARD11 PNP LGALS9

1.22e-04152455MP:0005153
MousePhenoabnormal renal water reabsorption

SLC9A3 NOS1

1.51e-046452MP:0010108
MousePhenospleen hyperplasia

LGALS9C LGALS9B CARD11 LGALS9

1.57e-0485454MP:0000693
MousePhenothymus hyperplasia

LGALS9C LGALS9B LGALS9

1.74e-0434453MP:0000708
MousePhenoabnormal B cell activation

LGALS9C LGALS9B CARD11 PNP LGALS9

1.85e-04166455MP:0008217
MousePhenoincreased susceptibility to induced arthritis

LGALS9C LGALS9B LGALS9

2.07e-0436453MP:0003724
MousePhenodecreased KLRG1-positive NK cell number

GMDS TRAPPC9

2.80e-048452MP:0012768
MousePhenoenlarged thymus

LGALS9C SLC24A4 LGALS9B CARD11 SPRYD4 LGALS9

3.24e-04292456MP:0000709
MousePhenoabnormal renal water transport

SLC9A3 NOS1

3.60e-049452MP:0011443
MousePhenoincreased NK T cell number

FAM3A GMDS CARD11

3.76e-0444453MP:0008039
MousePhenoabnormal lymph node B cell domain morphology

LGALS9C LGALS9B LGALS9

3.76e-0444453MP:0002344
MousePhenoabnormal thymus size

LGALS9C SLC24A4 LGALS9B LRP2 CARD11 SPRYD4 PNP LGALS9

3.85e-04564458MP:0002364
MousePhenoabnormal thymus morphology

LGALS9C SLC24A4 LGALS9B LRP2 CARD11 SRPX SPRYD4 PNP LGALS9

3.92e-04717459MP:0000703
MousePhenoautoimmune arthritis

LGALS9C LGALS9B ADAM8 LGALS9

3.93e-04108454MP:0002993
MousePhenoabnormal renal water homeostasis

SLC9A3 NOS1

4.49e-0410452MP:0011444
MousePhenoincreased alpha-beta T cell number

LGALS9C LGALS9B GMDS CARD11 PNP LGALS9

4.53e-04311456MP:0012764
MousePhenoabnormal T-helper 1 cell morphology

LGALS9C LGALS9B LGALS9

4.87e-0448453MP:0002433
MousePhenoabnormal lymph node cortex morphology

LGALS9C LGALS9B LGALS9

5.50e-0450453MP:0002343
MousePhenoabnormal lymphocyte morphology

LGALS9C ZBTB7A LGALS9B BTNL2 FAM3A GMDS CARD11 ADGRF5 SRPX PKHD1L1 TRAPPC9 PNP LGALS9

5.76e-0414834513MP:0002619
MousePhenoincreased T cell number

LGALS9C LGALS9B FAM3A GMDS CARD11 PNP LGALS9

7.41e-04475457MP:0005015
MousePhenoabnormal endocrine gland morphology

LGALS9C SLC24A4 LGALS9B ABCC8 LRP2 CARD11 SRPX TRAPPC9 SPRYD4 PNP LGALS9

7.94e-0411444511MP:0013560
MousePhenojoint inflammation

LGALS9C LGALS9B ADAM8 LGALS9

8.15e-04131454MP:0002933
MousePhenoabnormal KLRG1-positive NK cell number

GMDS TRAPPC9

9.00e-0414452MP:0012766
MousePhenodecreased effector memory CD8-positive, alpha-beta T cell number

GMDS CARD11

9.00e-0414452MP:0010851
MousePhenodecreased lymphocyte cell number

LGALS9C ZBTB7A LGALS9B GMDS CARD11 ADGRF5 PKHD1L1 TRAPPC9 PNP LGALS9

1.00e-039924510MP:0005016
MousePhenoabnormal joint physiology

LGALS9C LGALS9B ADAM8 LGALS9

1.19e-03145454MP:0031169
MousePhenoabnormal CD8-positive, naive alpha-beta T cell number

GMDS CARD11 PNP

1.29e-0367453MP:0013434
MousePhenodecreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number

GMDS CARD11

1.34e-0317452MP:0010169
MousePhenoabnormal phagocyte morphology

LGALS9C LGALS9B FAM3A GMDS ADGRF5 ADAM8 PKHD1L1 NOS1 TRAPPC9 LGALS9

1.37e-0310334510MP:0008251
MousePhenoabnormal gamma-delta T cell number

GMDS CARD11 TRAPPC9

1.41e-0369453MP:0008345
MousePhenoabnormal effector memory CD8-positive, alpha-beta T cell number

GMDS CARD11 PNP

1.41e-0369453MP:0010849
MousePhenoabnormal CD4-positive, alpha-beta T cell number

LGALS9C LGALS9B GMDS CARD11 PNP LGALS9

1.49e-03391456MP:0008073
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

9.58e-0615533PF00337
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

9.58e-0615533SM00908
DomainGALECTIN

LGALS9C LGALS9B LGALS9

9.58e-0615533PS51304
DomainGalectin_CRD

LGALS9C LGALS9B LGALS9

9.58e-0615533IPR001079
DomainGLECT

LGALS9C LGALS9B LGALS9

9.58e-0615533SM00276
DomainIg-like_fold

HMCN2 ZPBP BTNL2 MYPN KDR ADGRF5 PKHD1L1 IGSF3 EPHA5

1.49e-04706539IPR013783
Domain-

LGALS9C CELSR3 LGALS9B LGALS9

1.52e-04955342.60.120.200
DomainConA-like_dom

LGALS9C CELSR3 LGALS9B SPRYD4 LGALS9

3.84e-04219535IPR013320
DomainIg-like_dom

HMCN2 ZPBP BTNL2 MYPN KDR ADGRF5 IGSF3

5.20e-04503537IPR007110
Domain-

ZPBP BTNL2 MYPN KDR ADGRF5 PKHD1L1 IGSF3 EPHA5

5.22e-046635382.60.40.10
DomainIGc2

HMCN2 MYPN KDR ADGRF5 IGSF3

5.30e-04235535SM00408
DomainIg_sub2

HMCN2 MYPN KDR ADGRF5 IGSF3

5.30e-04235535IPR003598
DomainEGF-like_CS

HMCN2 CELSR3 LRP2 ADAM8 EPHA5

8.51e-04261535IPR013032
DomainEGF_2

HMCN2 CELSR3 LRP2 ADAM8 EPHA5

9.11e-04265535PS01186
DomainIG

HMCN2 BTNL2 MYPN KDR ADGRF5 IGSF3

1.19e-03421536SM00409
DomainIg_sub

HMCN2 BTNL2 MYPN KDR ADGRF5 IGSF3

1.19e-03421536IPR003599
DomainIg_I-set

HMCN2 MYPN KDR ADGRF5

2.06e-03190534IPR013098
DomainI-set

HMCN2 MYPN KDR ADGRF5

2.06e-03190534PF07679
DomainIG_LIKE

HMCN2 BTNL2 MYPN KDR ADGRF5 IGSF3

2.58e-03491536PS50835
DomainASX_HYDROXYL

HMCN2 CELSR3 LRP2

2.87e-03100533PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

HMCN2 CELSR3 LRP2

3.39e-03106533IPR000152
DomainGPS

CELSR3 ADGRF5

4.18e-0334532SM00303
DomainGPCR_2_secretin-like_CS

CELSR3 ADGRF5

4.18e-0334532IPR017983
DomainProtein_kinase_ATP_BS

CDK16 KDR CDK2 CDK3 EPHA5

4.33e-03379535IPR017441
DomainEGF_3

HMCN2 CELSR3 LRP2 ADAM8

4.42e-03235534PS50026
DomainGPS

CELSR3 ADGRF5

4.43e-0335532PF01825
DomainGPS

CELSR3 ADGRF5

4.68e-0336532PS50221
DomainGPS

CELSR3 ADGRF5

4.94e-0337532IPR000203
DomainEGF_CA

HMCN2 CELSR3 LRP2

5.02e-03122533SM00179
DomainEGF-like_Ca-bd_dom

HMCN2 CELSR3 LRP2

5.25e-03124533IPR001881
DomainEGF-like_dom

HMCN2 CELSR3 LRP2 ADAM8

5.41e-03249534IPR000742
DomainG_PROTEIN_RECEP_F2_1

CELSR3 ADGRF5

5.75e-0340532PS00649
DomainGPCR_2_extracellular_dom

CELSR3 ADGRF5

5.75e-0340532IPR001879
DomainG_PROTEIN_RECEP_F2_3

CELSR3 ADGRF5

5.75e-0340532PS50227
DomainEGF_1

HMCN2 CELSR3 LRP2 ADAM8

5.88e-03255534PS00022
DomainABC_transporter_CS

ABCC8 ABCA10

6.33e-0342532IPR017871
DomainER_TARGET

EDEM3 PDILT

7.87e-0347532PS00014
DomainABC_tran

ABCC8 ABCA10

8.20e-0348532PF00005
DomainABC_TRANSPORTER_2

ABCC8 ABCA10

8.20e-0348532PS50893
DomainABC_TRANSPORTER_1

ABCC8 ABCA10

8.53e-0349532PS00211
DomainG_PROTEIN_RECEP_F2_2

CELSR3 ADGRF5

8.87e-0350532PS00650
Domain7tm_2

CELSR3 ADGRF5

8.87e-0350532PF00002
DomainABC_transporter-like

ABCC8 ABCA10

8.87e-0350532IPR003439
Pubmed

Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.

LGALS9C LGALS9B LGALS9

3.54e-09354329458010
Pubmed

Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.

LGALS9C LGALS9B LGALS9

3.54e-09354319776007
Pubmed

Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.

LGALS9C LGALS9B LGALS9

3.54e-09354326582205
Pubmed

Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

LGALS9C LGALS9B LGALS9

3.54e-0935439153289
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9C LGALS9B LGALS9

3.54e-09354333316546
Pubmed

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.

LGALS9C LGALS9B LGALS9

3.54e-09354318974023
Pubmed

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

LGALS9C LGALS9B LGALS9

3.54e-0935439038233
Pubmed

Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.

LGALS9C LGALS9B LGALS9

3.54e-09354323144904
Pubmed

Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.

LGALS9C LGALS9B LGALS9

3.54e-09354329651447
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9C LGALS9B LGALS9

3.54e-09354328704475
Pubmed

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.

LGALS9C LGALS9B LGALS9

3.54e-09354321146220
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9C LGALS9B LGALS9

3.54e-09354323836896
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9C LGALS9B LGALS9

3.54e-0935437890611
Pubmed

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.

LGALS9C LGALS9B LGALS9

3.54e-09354322341088
Pubmed

Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.

LGALS9C LGALS9B LGALS9

3.54e-09354328990062
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9C LGALS9B LGALS9

3.54e-09354332380082
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9C LGALS9B LGALS9

3.54e-09354323667648
Pubmed

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.

LGALS9C LGALS9B LGALS9

3.54e-09354318579572
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9C LGALS9B LGALS9

3.54e-09354328877989
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9C LGALS9B LGALS9

3.54e-09354319800850
Pubmed

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.

LGALS9C LGALS9B LGALS9

3.54e-09354338987795
Pubmed

Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.

LGALS9C LGALS9B LGALS9

3.54e-09354316990264
Pubmed

Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.

LGALS9C LGALS9B LGALS9

3.54e-09354318005988
Pubmed

Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.

LGALS9C LGALS9B LGALS9

3.54e-09354323585851
Pubmed

Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.

LGALS9C LGALS9B LGALS9

3.54e-09354324477688
Pubmed

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

LGALS9C LGALS9B LGALS9

3.54e-09354329433546
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9C LGALS9B LGALS9

3.54e-09354337105392
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9C LGALS9B LGALS9

3.54e-09354336479526
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9C LGALS9B LGALS9

3.54e-09354323242525
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9C LGALS9B LGALS9

3.54e-09354319851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9C LGALS9B LGALS9

3.54e-09354333923930
Pubmed

Alarmin function of galectin-9 in murine respiratory tularemia.

LGALS9C LGALS9B LGALS9

3.54e-09354325898318
Pubmed

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.

LGALS9C LGALS9B LGALS9

3.54e-09354331937306
Pubmed

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.

LGALS9C LGALS9B LGALS9

3.54e-09354321426359
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9C LGALS9B LGALS9

3.54e-09354331969388
Pubmed

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

LGALS9C LGALS9B LGALS9

3.54e-09354318282810
Pubmed

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.

LGALS9C LGALS9B LGALS9

3.54e-09354335241678
Pubmed

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

LGALS9C LGALS9B LGALS9

3.54e-09354324083426
Pubmed

Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.

LGALS9C LGALS9B LGALS9

3.54e-09354337279535
Pubmed

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.

LGALS9C LGALS9B LGALS9

3.54e-09354325931247
Pubmed

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

LGALS9C LGALS9B LGALS9

3.54e-09354322627368
Pubmed

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.

LGALS9C LGALS9B LGALS9

3.54e-09354333153471
Pubmed

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

LGALS9C LGALS9B LGALS9

3.54e-09354322052881
Pubmed

Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.

LGALS9C LGALS9B LGALS9

3.54e-09354317560833
Pubmed

Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.

LGALS9C LGALS9B LGALS9

3.54e-09354335643073
Pubmed

Galectin-9 functionally impairs natural killer cells in humans and mice.

LGALS9C LGALS9B LGALS9

3.54e-09354323408620
Pubmed

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.

LGALS9C LGALS9B LGALS9

1.41e-08454338686388
Pubmed

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.

LGALS9C LGALS9B LGALS9

1.41e-08454322677125
Pubmed

Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.

LGALS9C LGALS9B LGALS9

1.41e-08454319234217
Pubmed

Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

LGALS9C LGALS9B LGALS9

1.41e-08454335715604
Pubmed

Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

LGALS9C LGALS9B LGALS9

1.41e-08454319017954
Pubmed

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

LGALS9C LGALS9B LGALS9

1.41e-08454333963043
Pubmed

Galectin-9: A novel promoter of atherosclerosis progression.

LGALS9C LGALS9B LGALS9

1.41e-08454336459823
Pubmed

Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.

LGALS9C LGALS9B LGALS9

1.41e-08454333107565
Pubmed

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.

LGALS9C LGALS9B LGALS9

1.41e-08454329611821
Pubmed

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.

LGALS9C LGALS9B LGALS9

1.41e-08454330763585
Pubmed

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.

LGALS9C LGALS9B LGALS9

1.41e-08454333727589
Pubmed

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

LGALS9C LGALS9B LGALS9

1.41e-08454319362679
Pubmed

The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.

LGALS9C LGALS9B LGALS9

1.41e-08454325578313
Pubmed

Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.

LGALS9C LGALS9B LGALS9

1.41e-08454329844236
Pubmed

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

LGALS9C LGALS9B LGALS9

1.41e-08454320463811
Pubmed

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.

LGALS9C LGALS9B LGALS9

1.41e-08454332855403
Pubmed

Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.

LGALS9C LGALS9B LGALS9

1.41e-08454323657851
Pubmed

[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].

LGALS9C LGALS9B LGALS9

1.41e-08454318826117
Pubmed

The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.

LGALS9C LGALS9B LGALS9

1.41e-08454324333756
Pubmed

The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.

LGALS9C LGALS9B LGALS9

1.41e-08454338853593
Pubmed

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.

LGALS9C LGALS9B LGALS9

1.41e-08454324958847
Pubmed

Galectin-9 binds IgM-BCR to regulate B cell signaling.

LGALS9C LGALS9B LGALS9

1.41e-08454330120235
Pubmed

[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].

LGALS9C LGALS9B LGALS9

1.41e-08454321575348
Pubmed

Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.

LGALS9C LGALS9B LGALS9

1.41e-08454318346632
Pubmed

Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.

LGALS9C LGALS9B LGALS9

1.41e-08454311839756
Pubmed

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

LGALS9C LGALS9B LGALS9

1.41e-08454319670381
Pubmed

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

LGALS9C LGALS9B LGALS9

1.41e-08454325450716
Pubmed

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

LGALS9C LGALS9B LGALS9

1.41e-08454316286920
Pubmed

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

LGALS9C LGALS9B LGALS9

1.41e-08454334369876
Pubmed

Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.

LGALS9C LGALS9B LGALS9

1.41e-08454333203936
Pubmed

Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.

LGALS9C LGALS9B LGALS9

1.41e-08454322021615
Pubmed

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.

LGALS9C LGALS9B LGALS9

3.53e-08554329242193
Pubmed

Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss.

LGALS9C LGALS9B LGALS9

3.53e-08554328951537
Pubmed

Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner.

LGALS9C LGALS9B LGALS9

3.53e-08554334847625
Pubmed

Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice.

LGALS9C LGALS9B LGALS9

3.53e-08554322469568
Pubmed

Astrocyte galectin-9 potentiates microglial TNF secretion.

LGALS9C LGALS9B LGALS9

3.53e-08554325158758
Pubmed

C/EBPzeta (CHOP/Gadd153) is a negative regulator of LPS-induced IL-6 expression in B cells.

LGALS9C LGALS9B LGALS9

3.53e-08554319782405
Pubmed

Embryonic implantation in galectin 1/galectin 3 double mutant mice.

LGALS9C LGALS9B LGALS9

3.53e-0855439566950
Pubmed

Feto-maternal immune regulation by TIM-3/galectin-9 pathway and PD-1 molecule in mice at day 14.5 of pregnancy.

LGALS9C LGALS9B LGALS9

3.53e-08554326278059
Pubmed

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.

LGALS9C LGALS9B LGALS9

3.53e-08554337352334
Pubmed

Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model.

LGALS9C LGALS9B LGALS9

3.53e-08554333664349
Pubmed

The glucose transporter 2 regulates CD8+ T cell function via environment sensing.

LGALS9C LGALS9B LGALS9

3.53e-08554337884694
Pubmed

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.

LGALS9C LGALS9B LGALS9

3.53e-08554321385853
Pubmed

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.

LGALS9C LGALS9B LGALS9

7.05e-08654328394331
Pubmed

Tim3 binding to galectin-9 stimulates antimicrobial immunity.

LGALS9C LGALS9B LGALS9

7.05e-08654320937702
Pubmed

Galectins in mouse embryogenesis.

LGALS9C LGALS9B LGALS9

7.05e-0865438674632
Pubmed

Tim-3/galectin-9 regulate the homeostasis of hepatic NKT cells in a murine model of nonalcoholic fatty liver disease.

LGALS9C LGALS9B LGALS9

7.05e-08654323296703
Pubmed

Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification.

LGALS9C LGALS9B KDR LGALS9

1.20e-072954424003143
Pubmed

Role of galectin-1 in the developing mouse olfactory system.

LGALS9C LGALS9B LGALS9

1.23e-0775438873770
Pubmed

Mammalian galectins bind galactoseβ1-4fucose disaccharide, a unique structural component of protostomial N-type glycoproteins.

LGALS9C LGALS9B LGALS9

1.97e-07854323751344
Pubmed

Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim‑3 and galectin‑9, in cervical cancer.

LGALS9C LGALS9B LGALS9

1.97e-07854331661141
Pubmed

Mesenchymal stem cells protect against sepsis-associated acute kidney injury by inducing Gal-9/Tim-3 to remodel immune homeostasis.

LGALS9C LGALS9B LGALS9

1.97e-07854336883358
Pubmed

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry.

LGALS9C LGALS9B LGALS9

2.95e-07954321670307
Pubmed

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells.

LGALS9C LGALS9B LGALS9

2.95e-07954325065622
InteractionNOS1AP interactions

LRP2 FGF11 NOS1 PNP EPHA5 SYNGAP1

5.04e-07113536int:NOS1AP
GeneFamilyGalectins

LGALS9C LGALS9B LGALS9

5.20e-0615423629
GeneFamilyCyclin dependent kinases

CDK16 CDK2 CDK3

2.92e-0526423496
GeneFamilyImmunoglobulin like domain containing

HMCN2 ZPBP KDR ADGRF5 IGSF3

8.12e-05193425594
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HMCN2 MYPN KDR ADGRF5

5.21e-04161424593
GeneFamilyAdenosine receptors|V-set domain containing

BTNL2 KDR IGSF3

6.38e-03163423590
CoexpressionBONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING

CDK16 EDEM3 KDR ADGRF5 EXOC7 ADAM8 CDK2 CDK3

8.71e-06506548M253
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

IGF2BP2 CDH22 CELSR3 SLC24A4 FGF11

1.15e-05143545M1935
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

IGF2BP2 CDH22 CELSR3 SLC24A4 FGF11

1.15e-05143545MM819
CoexpressionHUMMERICH_SKIN_CANCER_PROGRESSION_UP

LGALS9C LGALS9B ADAM8 LGALS9

5.45e-05100544MM514
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

IGF2BP2 CDH22 CELSR3 SLC24A4 FGF11

7.23e-05210545M2010
CoexpressionDESCARTES_ORGANOGENESIS_GRANULE_NEURONS

ABCC8 NOS1 EPHA5

8.34e-0541543MM3647
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

IGF2BP2 CDH22 CELSR3 SLC24A4 FGF11

8.44e-05217545MM861
CoexpressionAFFAR_YY1_TARGETS_UP

LGALS9C LGALS9B LRP2 KDR LGALS9

8.44e-05217545MM1156
ToppCellCOPD-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

SERPINE1 KDR CARD11 ADAM8 LGALS9

1.38e-061585458f66979e92f886d86cecbd26aaa0c5915c049734
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGF2BP2 WDR4 RELL2 SERPINE1 ADGRF5

1.61e-0616354563b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ZPBP LRP2 PKHD1L1 IGSF3 EPHA5

2.15e-06173545e05cddf5bf63cf419343ff229453327519765be8
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

ZPBP LRP2 PKHD1L1 IGSF3 EPHA5

2.15e-0617354574ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCellwk_15-18-Epithelial-PNS-SST+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CACNG7 CELSR3 ZPBP ABCC8 EPHA5

2.76e-06182545a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ABCC8 SERPINE1 SRPX PKHD1L1 NOS1

3.15e-061875452d20193a6cacdfa4877457c97b0077408942186c
ToppCellCOPD-Endothelial|COPD / Disease state, Lineage and Cell class

SERPINE1 KDR ADGRF5 SRPX PKHD1L1

3.68e-06193545093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCellEndothelial-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

ABCC8 SERPINE1 KDR SRPX NOS1

3.87e-06195545c3a0aa34b672c99cb3a2a4e9218412dbd19da3ca
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC8 SERPINE1 SRPX PKHD1L1 NOS1

4.06e-06197545b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC8 SERPINE1 SRPX PKHD1L1 NOS1

4.27e-061995453a4deea6e11a0555d27497b7c9983350797aac69
ToppCelldroplet-Lung-nan-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEURL3 ABCC8 BTNL2 ADAM8

3.94e-051575443cffedafff31efb5b3259194157b54a768367459
ToppCelldroplet-Lung-nan-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEURL3 ABCC8 BTNL2 ADAM8

3.94e-05157544f87e867a394b0453ebd92c592e80450caf5902cb
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

ABCC8 SRPX PKHD1L1 NOS1

4.24e-051605440cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC24A4 CARD11 FGF11 NOS1

4.35e-05161544cd41abb7ae659d3d314281783a0aaad562b26037
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYPN PDILT PKHD1L1 EPHA5

4.45e-05162544bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellcontrol-Epithelial-Ionocyte|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IMPA2 ADGRF5 GRIN3A EPHA5

4.78e-051655445cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IMPA2 ADGRF5 GRIN3A EPHA5

4.89e-051665446d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

CATSPERB KDR SRPX PKHD1L1

5.01e-0516754497d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IMPA2 ADGRF5 GRIN3A EPHA5

5.13e-05168544327b02f19f4a8607c033203824fdc60a1254331f
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

CDH22 PTCHD3 KDR PKHD1L1

5.13e-051685444977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGALS9B KDR ADGRF5 PKHD1L1

5.25e-05169544987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellIonocyte-iono-1|World / Class top

PDILT ADGRF5 FGF11 EPHA5

5.25e-051695444b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NEURL3 KDR ADGRF5 LGALS9

5.49e-051715443112d15f2a28cf4a71992db4971d960716dc1264
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IGF2BP2 WDR4 SERPINE1 ADGRF5

5.62e-05172544da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZPBP LRP2 PKHD1L1 IGSF3

5.75e-051735443d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDH22 CATSPERB KDR PKHD1L1

5.75e-051735447dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PTCHD3 KDR SRPX PKHD1L1

5.75e-05173544a81992965137195d20fc498f750975303961a828
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZPBP LRP2 PKHD1L1 IGSF3

5.75e-051735443aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYPN PDILT CATSPERB PKHD1L1

6.01e-051755449a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYPN PDILT CATSPERB PKHD1L1

6.01e-0517554454c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYPN PDILT CATSPERB PKHD1L1

6.01e-051755442b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 MYPN KDR ADGRF5

6.14e-0517654464e426f5e84884ce2c29acf6f4b958962a63927f
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

ABCC8 SRPX PKHD1L1 NOS1

6.14e-05176544043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDH22 ABCC8 CARD11 PKHD1L1

6.28e-0517754443dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KDR ADGRF5 NOS1 LGALS9

6.42e-05178544c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDR ADGRF5 PKHD1L1 LGALS9

6.56e-05179544dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CDH22 IMPA2 ADGRF5 EPHA5

6.70e-051805448af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NEURL3 KDR ADGRF5 DENND2B

6.70e-05180544d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HMCN2 KDR ADGRF5 LGALS9

6.70e-051805445861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellCOPD-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

SERPINE1 KDR ADGRF5 DENND2B

6.85e-0518154461608123959483ff60f07d8467996853c4371b6a
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH22 IMPA2 ADGRF5 EPHA5

6.85e-0518154440df0afcb6848202da54670e84f22d7c3a515d01
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH22 IMPA2 ADGRF5 EPHA5

6.85e-051815442b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH22 IMPA2 ADGRF5 EPHA5

6.85e-051815446aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH22 IMPA2 ADGRF5 EPHA5

6.85e-0518154440d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NEURL3 KDR ADGRF5 LGALS9

7.00e-05182544345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CDH22 IMPA2 ADGRF5 EPHA5

7.15e-05183544ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

ABCC8 SRPX PKHD1L1 NOS1

7.15e-0518354446be9f96755c7b65aeac061d95d15abeb6466034
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KDR ADGRF5 NOS1 LGALS9

7.30e-05184544a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CDH22 IMPA2 ADGRF5 EPHA5

7.30e-0518454458d36577eff814d46d72f031f3533d71549e3d6e
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

HMCN2 SERPINE1 SRPX NOS1

7.30e-051845440f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

SERPINE1 KDR ADGRF5 DENND2B

7.30e-051845445f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

HMCN2 SERPINE1 SRPX ABCA10

7.45e-051855448f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

CDH22 CATSPERB KDR PKHD1L1

7.45e-051855444a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

CDH22 CATSPERB KDR PKHD1L1

7.45e-0518554436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

SERPINE1 KDR ADGRF5 DENND2B

7.45e-05185544a28187c2fd23564314b35759479ff2ca21f61485
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ZBTB7A CELSR3 RELL2 EPHA5

7.61e-051865449d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KDR ADGRF5 PNP LGALS9

7.77e-0518754429b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCellmoderate-Epithelial-Ionocyte|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CDH22 IMPA2 ADGRF5 EPHA5

7.77e-051875443e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

SERPINE1 KDR ADGRF5 DENND2B

7.77e-0518754454d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

ABCC8 SRPX PKHD1L1 NOS1

7.93e-05188544d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDH22 CATSPERB KDR PKHD1L1

7.93e-05188544c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SERPINE1 KDR ADGRF5 PNP

7.93e-05188544986aaf31161ec3d1e6c76ee2dd17f44848a21f7e
ToppCellwk_08-11-Hematologic_Lymphocytic-NK-Intermediate_NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LGALS9C LGALS9B CARD11 ADAM8

7.93e-05188544a8170e4ce6406af9f5ad5317e6e26efa7bc66411
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZPBP KDR GRIN3A NOS1

7.93e-051885443139540a656c0436b2123ea50741ff8d00112165
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDH22 CATSPERB KDR PKHD1L1

7.93e-05188544aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SERPINE1 KDR ADGRF5 DENND2B

8.10e-05189544b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellControl-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

ABCC8 SRPX PKHD1L1 NOS1

8.10e-05189544f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGF11 PKHD1L1 TRAPPC9 LGALS9

8.10e-051895440739baad9a7da511dd3d7249f84299aee88370a1
ToppCellIPF-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

SERPINE1 KDR ADGRF5 DENND2B

8.10e-05189544ea3aa3ef38f1d405bb527ae383cd12c551a3dd6f
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

SERPINE1 GMDS ADGRF5 PKHD1L1

8.10e-05189544c81787a8c662db5d7814c583dd64562857629e81
ToppCellmoderate-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SERPINE1 KDR ADGRF5 SRPX

8.10e-0518954422a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDH22 CATSPERB KDR PKHD1L1

8.26e-05190544876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellEndothelial-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

ABCC8 KDR SRPX NOS1

8.26e-051905446e83fa0eb8cabe0ffb35375f16e6bf3755ec4977
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

ABCC8 SERPINE1 KDR ADGRF5

8.26e-05190544812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CDH22 IMPA2 ADGRF5 EPHA5

8.26e-0519054405a2c3549b68f49081723bf35db14974274419d5
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCC8 SERPINE1 SRPX PKHD1L1

8.26e-051905441caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KDR ADGRF5 PNP LGALS9

8.26e-051905441307688255a1250fa300edf2c41f1affe31dcc98
ToppCellPND01-03-samps-Endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KDR ADGRF5 DENND2B LGALS9

8.26e-051905441357bd4527399d7013ee33272bda7453f472999a
ToppCellIPF-Endothelial-VE_Capillary_A|IPF / Disease state, Lineage and Cell class

SERPINE1 KDR ADGRF5 DENND2B

8.26e-05190544b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SERPINE1 KDR ADGRF5 DENND2B

8.26e-051905440e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SERPINE1 KDR ADGRF5 DENND2B

8.26e-051905440a351609a72fd638c84b2435782e312ee6a33aac
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KDR ADGRF5 DENND2B LGALS9

8.26e-051905445130fb325f80f591b9b36beacb8072c4472304f2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDH22 CATSPERB KDR PKHD1L1

8.26e-05190544be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDH22 CATSPERB KDR PKHD1L1

8.26e-0519054409a8855901c3c9332dbaab3e40166485b696d0f1
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

ABCC8 KDR ADGRF5 SRPX

8.43e-05191544c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SERPINE1 KDR ADGRF5 DENND2B

8.43e-05191544f229abf69a1217194f74b0502486907e07dba989
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDR ADGRF5 PKHD1L1 LGALS9

8.60e-05192544fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

SERPINE1 KDR ADGRF5 DENND2B

8.60e-051925441e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDR ADGRF5 PKHD1L1 LGALS9

8.60e-051925444e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGF2BP2 IMPA2 ADAM8 PNP

8.60e-05192544dfb9101622f7d2f2c392e850cff07becfc8c655e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGF2BP2 IMPA2 ADAM8 PNP

8.60e-05192544d39133cf1a20af6f2970188630fc3b27a4cfc9c5
ToppCell18-Distal-Immune-Hematopoietic,_Natural_Killer_Cell|Distal / Age, Tissue, Lineage and Cell class

LGALS9C LGALS9B CARD11 ADAM8

8.60e-05192544dd47d47d0a7219771b275c4cf5f2b768424216c8
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINE1 KDR ADGRF5 DENND2B

8.60e-05192544f094ac378e635cf5820e8a8b7a0152073a51ceae
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCC8 SRPX PKHD1L1 NOS1

8.78e-05193544c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS9C LGALS9B CARD11 ADAM8

8.78e-0519354454604c2c5dce2ff6f3ec7ca82b595b09b8cdafe8
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC8 SRPX PKHD1L1 NOS1

8.78e-051935449ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCellLA|World / Chamber and Cluster_Paper

HMCN2 SERPINE1 LRP2 ABCA10

8.78e-05193544d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCC8 SRPX PKHD1L1 NOS1

8.78e-05193544682ce63b73a7d02eef240673db67058d7507f744
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

SERPINE1 CATSPERB SRPX ABCA10

8.95e-0519454411c79a8c56ece42713b04b321982e41e239f07a5
ToppCellEndothelial-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ABCC8 KDR SRPX NOS1

8.95e-05194544abea887dd472c1a0d572e690bc8914c1b94712ad
ComputationalPlacenta genes.

ZBTB7A IMPA2 SERPINE1 SRPX DENND2B IGSF3 CDK2 PNP

2.82e-05463308MODULE_38
Diseaseneurilemmoma (is_marker_for)

SERPINE1 KDR

2.92e-055512DOID:3192 (is_marker_for)
Diseasebrain ischemia (implicated_via_orthology)

SERPINE1 KDR NOS1

3.06e-0535513DOID:2316 (implicated_via_orthology)
Diseasechronic kidney disease

SLC24A4 MYO19 MYPN PDILT LRP2

5.35e-05235515EFO_0003884
Diseasehypertension (implicated_via_orthology)

SLC9A3 SERPINE1 LRP2 NOS1

7.21e-05128514DOID:10763 (implicated_via_orthology)
DiseaseSchizophrenia

CDK16 IGF2BP2 IMPA2 LRP2 KDR GRIN3A NOS1 SYNGAP1

1.27e-04883518C0036341
Diseaseretinopathy of prematurity (biomarker_via_orthology)

KDR NOS1

1.91e-0412512DOID:13025 (biomarker_via_orthology)
Diseaseanorexia nervosa

CELSR3 LRP2 SRPX

2.45e-0470513MONDO_0005351
Diseaseoligoclonal band measurement, multiple sclerosis

BTNL2 PRKRA

2.63e-0414512EFO_0005206, MONDO_0005301
Diseaserenovascular hypertension (biomarker_via_orthology)

SLC9A3 NOS1

4.92e-0419512DOID:1591 (biomarker_via_orthology)
Diseaseend stage renal disease (implicated_via_orthology)

SERPINE1 NOS1

5.46e-0420512DOID:783 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease (is_marker_for)

SERPINE1 KDR NOS1

6.40e-0497513DOID:3083 (is_marker_for)
Diseaseimpotence (biomarker_via_orthology)

KDR NOS1

6.62e-0422512DOID:1875 (biomarker_via_orthology)
Diseaseuromodulin measurement

BTNL2 PDILT

9.27e-0426512EFO_0021778
DiseaseGlioblastoma Multiforme

ZBTB7A CDK2 CDK3

9.46e-04111513C1621958
Diseaseglucose tolerance test

IGF2BP2 ABCC8

1.00e-0327512EFO_0004307
DiseaseIntellectual Disability

CDK16 WDR4 LRP2 PRKRA SYNGAP1

1.03e-03447515C3714756
DiseaseTYPE 2 DIABETES MELLITUS

IGF2BP2 ABCC8

1.08e-0328512125853
DiseaseType 2 diabetes mellitus

IGF2BP2 ABCC8

1.08e-0328512cv:C0011860
DiseaseColorectal Carcinoma

CDH22 ABCC8 PDILT LRP2 KDR ABCA10

1.29e-03702516C0009402
DiseaseColorectal Neoplasms

CDH22 ABCC8 KDR ABCA10

1.34e-03277514C0009404
Diseaseasthma (is_marker_for)

SERPINE1 KDR ADAM8

1.36e-03126513DOID:2841 (is_marker_for)
Diseasefasting blood glucose measurement

IGF2BP2 SLC24A4 WDR4 GMDS

1.53e-03287514EFO_0004465
Diseasepack-years measurement, systolic blood pressure

LRP2 TRAPPC9

1.59e-0334512EFO_0006335, EFO_0006526
DiseaseParkinsonism (biomarker_via_orthology)

ABCC8 NOS1

1.59e-0334512DOID:0080855 (biomarker_via_orthology)
Diseasepeak expiratory flow

IGF2BP2 SLC9A3 MYPN GMDS KDR

1.66e-03498515EFO_0009718

Protein segments in the cluster

PeptideGeneStartEntry
SELFHFRVTVISGVT

CATSPERB

1021

Q9H7T0
ALVITSIPIVFHTGF

ABCA10

196

Q8WWZ4
STPVFVHRDGVEVTE

BTNL2

71

Q9UIR0
VVRHLAVFPDTITGA

EPHA5

236

P54756
EVHAASGSLPVFVVV

ADAM8

646

P78325
VSEVFIRFFVETVGH

DENND2B

1026

P78524
TPELFASVIGVFITH

SLC24A4

151

Q8NFF2
THVSELVFFIVVGVI

OR8B4

191

Q96RC9
FVIATGEVHSVREFV

GMDS

271

O60547
VETIHISAAGFPIRV

MYO19

646

Q96H55
VAFRVEIHTVPTIRS

HMCN2

3676

Q8NDA2
VPFHRVDTISVNGSV

LGALS9C

126

Q6DKI2
VPFHRVDTISVNGSV

LGALS9B

126

Q3B8N2
VPFHRVDTISVNGSV

LGALS9

126

O00182
QIVSHPFFGRVVLTA

EDEM3

651

Q9BZQ6
LVPEFGVSSSHVRVL

PGS1

86

Q32NB8
PFLITVRQHIIFGIS

LRP2

1746

P98164
EVIVRIIGHFFASQT

IGF2BP2

556

Q9Y6M1
HRFPTVAVSIGFAVR

IMPA2

111

O14732
IVRHDFSTVLTVFPI

EXOC7

421

Q9UPT5
RVVTLIEHPFVFTRE

GRIN3A

516

Q8TCU5
THVVLILRGPEGFTT

NOS1

91

P29475
FTHFNLIPVGLRVVT

FGF11

101

Q92914
FIRPLHEGTLVFVAS

FAM3A

136

P98173
AFGVPLRTYTHEVVT

CDK3

151

Q00526
PVGTVEFHDLVTFTR

IGSF3

586

O75054
LHFIFRILGTPTEET

CDK16

371

Q00536
VFTAFVISNIGHIRP

CACNG7

111

P62955
IVRELHVYGSVVPVS

ELP3

471

Q9H9T3
HFTVDPKTGVIRTAV

CDH22

216

Q9UJ99
AFGVPVRTYTHEVVT

CDK2

151

P24941
SPVVSVAVFHGRNFL

CELSR3

2441

Q9NYQ7
VTFPVRVFHLLGVDT

PNP

96

P00491
PTRRFSTIVVEEGHE

CARD11

111

Q9BXL7
FEATSVTVIPVFHLA

PTCHD3

376

Q3KNS1
FLFVVRHNPTGTVLF

SERPINE1

381

P05121
VIGRFHVTLDSVLVF

PDILT

211

Q8N807
TTVFSVGRFRVTHIE

RELL2

161

Q8NC24
SVVHTLQTDFRGPVV

SPRYD4

171

Q8WW59
TRFTKHVRIIEPGFV

SLC9A3

276

P48764
LRHITVVELVGVFPT

SRPX

371

P78539
PIAAVLITFVGHVSF

ABCC8

551

Q09428
LTTVFPGTNLVFHII

ADGRF5

1236

Q8IZF2
RVTETVHTSYGPITV

C15orf61

131

A6NNL5
VTVPVATLAGRHFTE

SYNGAP1

346

Q96PV0
GTIPVEIHTATVIFV

PKHD1L1

3926

Q86WI1
RTTFHDGIVFSQRPV

NEURL3

41

Q96EH8
RSDVQIHVPTFTFRV

PRKRA

56

O75569
IHVPTFTFRVTVGDI

PRKRA

61

O75569
FISAFLVRVPSSVGH

ZPBP

31

Q9BS86
HVEVEPSVFFTRVST

TRAPPC9

881

Q96Q05
GHTEFVSRISVVPTQ

WDR4

186

P57081
RVISFHVTRGPEITL

KDR

541

P35968
VVILVEGREFPTHRS

ZBTB7A

36

O95365
LKHFRVTEGSPVTFT

MYPN

951

Q86TC9