Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	piccolo-bassoon transport vesicle	BSN DYNC1I1	5.61e-05	2	157	2	GO:1990257
HumanPheno	Predominantly lower limb lymphedema	FLT4 PIEZO1 CELSR1 DNMT1	1.17e-06	9	52	4	HP:0003550
Domain	DUF4795	C16orf96 QRICH2	6.41e-05	2	150	2	IPR032013
Domain	DUF4795	C16orf96 QRICH2	6.41e-05	2	150	2	PF16043
Domain	Znf_piccolo	PCLO BSN	6.41e-05	2	150	2	IPR008899
Domain	zf-piccolo	PCLO BSN	6.41e-05	2	150	2	PF05715
Domain	MARK/par1	MARK3 MARK4	3.80e-04	4	150	2	IPR033624
Domain	C5_MTASE_1	DNMT1 DNMT3B	3.80e-04	4	150	2	PS00094
Domain	C5_MTASE_2	DNMT1 DNMT3B	3.80e-04	4	150	2	PS00095
Domain	SAM_MT_C5	DNMT1 DNMT3B	3.80e-04	4	150	2	PS51679
Domain	DNA_methylase	DNMT1 DNMT3B	3.80e-04	4	150	2	PF00145
Domain	DUF3338	FRMD4A INAVA	3.80e-04	4	150	2	PF11819
Domain	C5_MeTfrase	DNMT1 DNMT3B	3.80e-04	4	150	2	IPR001525
Domain	DUF3338	FRMD4A INAVA	3.80e-04	4	150	2	IPR021774
Domain	C5_DNA_meth_AS	DNMT1 DNMT3B	3.80e-04	4	150	2	IPR018117
Domain	KA1	MARK3 MARK4	6.31e-04	5	150	2	PF02149
Domain	KA1_dom	MARK3 MARK4	6.31e-04	5	150	2	IPR001772
Domain	KA1	MARK3 MARK4	6.31e-04	5	150	2	PS50032
Domain	-	MARK3 MARK4	6.31e-04	5	150	2	3.30.310.80
Domain	PH_dom-like	DOCK10 ARHGAP9 ARHGEF11 NIBAN3 SPTBN4 FRMD4A SBF2 EPS8L3 AGAP7P AGAP4 FRMD5	6.67e-04	426	150	11	IPR011993
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SHROOM3 RRP1B ZNF212 PIEZO1 KIF21A PHRF1 ZNF507 LAMA5 SMPD4 SF3B3 NRXN2 CASKIN1 BOP1 RPRD2 CACNA1G AGAP7P BSN AGAP4 DAGLA	5.91e-12	529	160	19	14621295
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NELFE SRRM1 SHROOM3 SORBS2 MARK3 KIAA1671 NKD2 CSNK1D MAP4K1 KIAA1217 MARK4 BUB1B FAM83G GNAS CAMSAP1 SRRM2 DNMT1 MAP3K2	1.04e-07	861	160	18	36931259
Pubmed	Functional analysis of secreted and transmembrane proteins critical to mouse development.	MBTPS1 FN1 MDM2 BIRC6 PTK7	2.99e-07	31	160	5	11431694
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SORBS2 FN1 ZNF212 APC2 DVL3 LAMA5 SPTBN4 NGRN NKD2 CSNK1D CIBAR1 RPRD2 AGAP7P DNMT1	3.60e-07	560	160	14	21653829
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MBTPS1 SHROOM3 MAN2B2 WWOX MARK3 BRWD3 FAF1 PTK7 KIAA1671 SPTBN4 PTPRB CSNK1D KIAA1217 SBF2 SEMA3B LRP1 RPRD2 LRRC7 GNAS NRG3 SYTL1 DAGLA FAM149A	3.72e-07	1489	160	23	28611215
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NELFE SRRM1 SORBS2 HIRIP3 ZC3H13 PHRF1 ZNF507 BUD13 ATF2 RNPS1 MAP4K1 PPP1R18 SRRM2 PRG4 NIPBL DNMT1	6.45e-07	774	160	16	15302935
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	SRRM1 SORBS2 FN1 MARK3 APC2 CSNK1D CASKIN1 MARK4 LRRC7 AGAP7P AGAP4 DAGLA	8.13e-07	430	160	12	32581705
Pubmed	Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells.	FUT4 DNMT1 DNMT3B	9.49e-07	5	160	3	15063176
Pubmed	Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development.	SMAD1 SMAD3 DNMT3B	9.49e-07	5	160	3	29637597
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRRM1 SORBS2 RRP1B ZC3H13 KIAA1671 RNPS1 KIAA1217 MYPN PPP1R18 RPRD2 SRRM2	1.01e-06	361	160	11	30344098
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHROOM3 SORBS2 KIF21A APC2 ARHGEF11 SPTBN4 PALS1 KIAA1217 CASKIN1 DIAPH2 LRP1 LRRC7 BSN CAMSAP1 UNC79 NIPBL DNMT1	2.43e-06	963	160	17	28671696
Pubmed	Notch signaling functions in lymphatic valve formation.	FLT4 FN1 NOTCH4	3.30e-06	7	160	3	24917500
Pubmed	CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses.	CDCA7 DNMT1 DNMT3B	3.30e-06	7	160	3	38335290
Pubmed	Functional proteomics mapping of a human signaling pathway.	NPR1 FLT4 FN1 DVL3 LAMA5 ARHGAP9 PSMD8 FAF1 LRP1 ASB2 CAMSAP1 SMAD1 SMAD3	3.89e-06	591	160	13	15231748
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SRRM1 ZNF212 PRSS56 PHRF1 LPCAT4 BUD13 C16orf96 MDM2 BRWD3 KIAA1671 SF3B3 EML5 RNPS1 CIBAR1 MARK4 LRP1 POLDIP2 SRRM2	4.25e-06	1116	160	18	31753913
Pubmed	Galectin-1 stimulates motility of human umbilical cord blood-derived mesenchymal stem cells by downregulation of smad2/3-dependent collagen 3/5 and upregulation of NF-κB-dependent fibronectin/laminin 5 expression.	FN1 LAMA5 SMAD3	5.26e-06	8	160	3	24503541
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SHROOM3 APC2 MDM2 APOBR KIAA1671 MAP4K1 INAVA BSN CAMSAP1 SMAD1 DNMT3B	5.42e-06	430	160	11	35044719
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	SRRM1 WWOX SF3B3 RNPS1 DIAPH2 RPRD2 SRRM2	7.70e-06	154	160	7	16055720
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	FN1 LAMA5 MDM2 ATF2 CSNK1D BUB1B GNAS PIK3R5 SMAD1 SMAD3	9.33e-06	371	160	10	25241761
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SRRM1 HIRIP3 RRP1B ZC3H13 BIRC6 RPRD2 SRRM2	1.12e-05	163	160	7	22113938
Pubmed	Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.	LAMA5 SMAD1 SMAD3	2.04e-05	12	160	3	17460146
Pubmed	BNP-induced activation of cGMP in human cardiac fibroblasts: interactions with fibronectin and natriuretic peptide receptors.	NPR1 FN1	2.10e-05	2	160	2	16986166
Pubmed	Association of DNMT1 and DNMT3B polymorphisms with breast cancer risk in Han Chinese women from South China.	DNMT1 DNMT3B	2.10e-05	2	160	2	23079992
Pubmed	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	PCLO BSN	2.10e-05	2	160	2	23403927
Pubmed	Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis.	DNMT1 DNMT3B	2.10e-05	2	160	2	25746661
Pubmed	Mechanistic and biological significance of DNA methyltransferase 1 upregulated by growth factors in human hepatocellular carcinoma.	DNMT1 DNMT3B	2.10e-05	2	160	2	25420499
Pubmed	Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.	PCLO BSN	2.10e-05	2	160	2	26793095
Pubmed	The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding.	WWOX SMAD3	2.10e-05	2	160	2	24330518
Pubmed	Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis.	PCLO BSN	2.10e-05	2	160	2	20332206
Pubmed	[Expression of DNA methyltransferases in salivary adenoid cystic carcinoma and its association with the CpG islands methylation of tumor suppressor genes].	DNMT1 DNMT3B	2.10e-05	2	160	2	17067458
Pubmed	Ectopic ERK expression induces phenotypic conversion of C10 cells and alters DNA methyltransferase expression.	DNMT1 DNMT3B	2.10e-05	2	160	2	22559742
Pubmed	DNA methyltransferases 1 and 3B are required for hepatitis C virus infection in cell culture.	DNMT1 DNMT3B	2.10e-05	2	160	2	23545144
Pubmed	Active zone density is conserved during synaptic growth but impaired in aged mice.	PCLO BSN	2.10e-05	2	160	2	21935939
Pubmed	DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis.	DNMT1 DNMT3B	2.10e-05	2	160	2	19465937
Pubmed	Influence of DNMT genotype on global and site specific DNA methylation patterns in neonates and pregnant women.	DNMT1 DNMT3B	2.10e-05	2	160	2	24098518
Pubmed	The SRm160/300 splicing coactivator subunits.	SRRM1 SRRM2	2.10e-05	2	160	2	10668804
Pubmed	DNA methyltransferase haplotype is associated with Alzheimer's disease.	DNMT1 DNMT3B	2.10e-05	2	160	2	25038421
Pubmed	H1 linker histone promotes epigenetic silencing by regulating both DNA methylation and histone H3 methylation.	DNMT1 DNMT3B	2.10e-05	2	160	2	23302691
Pubmed	DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.	DNMT1 DNMT3B	2.10e-05	2	160	2	11932749
Pubmed	Suppressing effects of down-regulating DNMT1 and DNMT3b expression on the growth of human cholangiocarcinoma cell line.	DNMT1 DNMT3B	2.10e-05	2	160	2	18563322
Pubmed	Effect of 50 Hz Extremely Low-Frequency Electromagnetic Fields on the DNA Methylation and DNA Methyltransferases in Mouse Spermatocyte-Derived Cell Line GC-2.	DNMT1 DNMT3B	2.10e-05	2	160	2	26339596
Pubmed	Circadian metabolic regulation through crosstalk between casein kinase 1δ and transcriptional coactivator PGC-1α.	PPARGC1A CSNK1D	2.10e-05	2	160	2	22052997
Pubmed	Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling.	FAM83G SMAD1	2.10e-05	2	160	2	24554596
Pubmed	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	PCLO BSN	2.10e-05	2	160	2	25652077
Pubmed	Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization.	DNMT1 DNMT3B	2.10e-05	2	160	2	38376465
Pubmed	Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas.	DNMT1 DNMT3B	2.10e-05	2	160	2	21229291
Pubmed	Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors.	SMAD1 SMAD3	2.10e-05	2	160	2	20147459
Pubmed	DNMT1 and DNMT3B gene variants and their association with endometriosis in South Indian women.	DNMT1 DNMT3B	2.10e-05	2	160	2	34697715
Pubmed	Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.	DNMT1 DNMT3B	2.10e-05	2	160	2	14559786
Pubmed	[Effects of Dnmt1 and Dnmt3b in mucoepidermoid carcinoma of salivary glands].	DNMT1 DNMT3B	2.10e-05	2	160	2	30411123
Pubmed	No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations.	DNMT1 DNMT3B	2.10e-05	2	160	2	23636699
Pubmed	The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.	FN1 LRP1	2.10e-05	2	160	2	11867643
Pubmed	State-dependent changes in the expression of DNA methyltransferases in mood disorder patients.	DNMT1 DNMT3B	2.10e-05	2	160	2	21592522
Pubmed	DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression.	CIDEA DNMT3B	2.10e-05	2	160	2	37703946
Pubmed	LRP1 is required for novobiocin-mediated fibronectin turnover.	FN1 LRP1	2.10e-05	2	160	2	30061663
Pubmed	Effects on biological behavior of bladder carcinoma T24 cells via silencing DNMT1 and/or DNMT3b with shRNA in vitro.	DNMT1 DNMT3B	2.10e-05	2	160	2	19399408
Pubmed	SUV39H1-Mediated DNMT1 is Involved in the Epigenetic Regulation of Smad3 in Cervical Cancer.	SMAD3 DNMT1	2.10e-05	2	160	2	32698743
Pubmed	Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.	PCLO BSN	2.10e-05	2	160	2	27321892
Pubmed	Two-stage case-control study of DNMT-1 and DNMT-3B gene variants and breast cancer risk.	DNMT1 DNMT3B	2.10e-05	2	160	2	19798569
Pubmed	DNMT3B (C46359T) polymorphisms and immunoexpression of DNMT3b and DNMT1 proteins in oral lichen planus.	DNMT1 DNMT3B	2.10e-05	2	160	2	22236544
Pubmed	No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.	PCLO BSN	2.10e-05	2	160	2	32493491
Pubmed	Active vitamin D induces gene-specific hypomethylation in prostate cancer cells developing vitamin D resistance.	DNMT1 DNMT3B	2.10e-05	2	160	2	32159363
Pubmed	Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study.	DNMT1 DNMT3B	2.10e-05	2	160	2	27169697
Pubmed	Haplotypes of DNMT1 and DNMT3B are associated with mutagen sensitivity induced by benzo[a]pyrene diol epoxide among smokers.	DNMT1 DNMT3B	2.10e-05	2	160	2	18499700
Pubmed	DNMT1 and DNMT3B genetic polymorphisms affect the clinical course and outcome of melanoma patients.	DNMT1 DNMT3B	2.10e-05	2	160	2	30950914
Pubmed	Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer.	DNMT1 DNMT3B	2.10e-05	2	160	2	28300471
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	NELFE SRRM1 HIRIP3 RRP1B ZC3H13 MYPN FAM83G BOP1 RPRD2 SRRM2 NIPBL	2.33e-05	503	160	11	16964243
Pubmed	Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.	FLT4 LAMA5 CELSR1	2.64e-05	13	160	3	27789626
Pubmed	A Combinatorial CRISPR-Cas9 Screen Identifies Ifenprodil as an Adjunct to Sorafenib for Liver Cancer Treatment.	NPR1 FLT4 PTK7	2.64e-05	13	160	3	34666996
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	SRRM1 PHRF1 BUD13 SF3B3 RNPS1 SRRM2 NIPBL SMAD1	2.86e-05	259	160	8	30404004
Pubmed	Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.	MARK3 CSNK1D MAP4K1 MARK4 MAP3K2	3.12e-05	78	160	5	17192257
Pubmed	A targeted mutation of Nkd1 impairs mouse spermatogenesis.	FN1 TBATA NKD2	3.35e-05	14	160	3	15546883
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	SRRM1 RRP1B DVL3 PALS1 RNPS1 PPP1R18 SRRM2 FRMD5	3.84e-05	270	160	8	24366813
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FN1 LPAR5 ZC3H13 KIF21A PCLO ARHGAP9 BIRC6 QRICH2 KIAA1671 ALDH16A1 KCNS2 LRRC7 PRG4	3.91e-05	736	160	13	29676528
Pubmed	Tbx1 genetically interacts with the transforming growth factor-β/bone morphogenetic protein inhibitor Smad7 during great vessel remodeling.	FN1 SMAD1 SMAD3	4.17e-05	15	160	3	23011393
Pubmed	Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice.	PIK3R5 SMAD1 SMAD3	4.17e-05	15	160	3	26367869
Pubmed	The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.	DVL3 PTK7 CELSR1	5.12e-05	16	160	3	22771245
Pubmed	Cell-matrix signals specify bone endothelial cells during developmental osteogenesis.	FLT4 FN1 LAMA5	5.12e-05	16	160	3	28218908
Pubmed	Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.	BUB1B DNMT1 DNMT3B	6.20e-05	17	160	3	14519686
Pubmed	Expression and regulation of DNA methyltransferases in human endometrium.	DNMT1 DNMT3B	6.29e-05	3	160	2	20970125
Pubmed	Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.	DNMT1 DNMT3B	6.29e-05	3	160	2	15456861
Pubmed	Rare Variants in LAMA5 Gene associated with FLT4 and FOXC2 Mutations in Primary Lymphedema May Contribute to Severity.	FLT4 LAMA5	6.29e-05	3	160	2	29908552
Pubmed	DNMT1 and DNMT3B regulate tumorigenicity of human prostate cancer cells by controlling RAD9 expression through targeted methylation.	DNMT1 DNMT3B	6.29e-05	3	160	2	32780107
Pubmed	Expression and clinicopathological significance of DNA methyltransferase 1, 3A and 3B in tamoxifen-treated breast cancer patients.	DNMT1 DNMT3B	6.29e-05	3	160	2	30359738
Pubmed	High expression of DNA methyltransferases in primary human medulloblastoma.	DNMT1 DNMT3B	6.29e-05	3	160	2	27543768
Pubmed	DNA methyltransferases 1, 3a, and 3b overexpression and clinical significance in gastroenteropancreatic neuroendocrine tumors.	DNMT1 DNMT3B	6.29e-05	3	160	2	20381114
Pubmed	Targeting DNA methylation for treating triple-negative breast cancer.	DNMT1 DNMT3B	6.29e-05	3	160	2	31755366
Pubmed	DNA methylation by DNMT1 and DNMT3b methyltransferases is driven by the MUC1-C oncoprotein in human carcinoma cells.	DNMT1 DNMT3B	6.29e-05	3	160	2	27212035
Pubmed	Epigenetic regulation of myofibroblast differentiation by DNA methylation.	DNMT1 DNMT3B	6.29e-05	3	160	2	20489138
Pubmed	Long non-coding RNA DBH-AS1 promotes cancer progression in diffuse large B-cell lymphoma by targeting FN1 via RNA-binding protein BUD13.	FN1 BUD13	6.29e-05	3	160	2	32091157
Pubmed	Expression of DNA methyltransferases 1 and 3B correlates with EZH2 and this 3-marker epigenetic signature predicts outcome in glioblastomas.	DNMT1 DNMT3B	6.29e-05	3	160	2	26892683
Pubmed	DNA methyltransferases control telomere length and telomere recombination in mammalian cells.	DNMT1 DNMT3B	6.29e-05	3	160	2	16565708
Pubmed	DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.	DNMT1 DNMT3B	6.29e-05	3	160	2	20587527
Pubmed	Progressive up-regulation of genes encoding DNA methyltransferases in the colorectal adenoma-carcinoma sequence.	DNMT1 DNMT3B	6.29e-05	3	160	2	17538945
Pubmed	Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer.	DNMT1 DNMT3B	6.29e-05	3	160	2	18414412
Pubmed	[Biochemistry of DNA methyltransferases].	DNMT1 DNMT3B	6.29e-05	3	160	2	18536344
Pubmed	Increased CXCR4 expression in AsPC1 pancreatic carcinoma cells with RNA interference-mediated knockdown of DNMT1 and DNMT3B.	DNMT1 DNMT3B	6.29e-05	3	160	2	19932585
Pubmed	Superovulation alters DNA methyltransferase protein expression in mouse oocytes and early embryos.	DNMT1 DNMT3B	6.29e-05	3	160	2	29164502
Pubmed	Gene-gene and gene-sex epistatic interactions of DNMT1, DNMT3A and DNMT3B in autoimmune thyroid disease.	DNMT1 DNMT3B	6.29e-05	3	160	2	27237591
Pubmed	Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases.	DNMT1 DNMT3B	6.29e-05	3	160	2	12145218
Interaction	YWHAG interactions	NELFE SRRM1 SHROOM3 SORBS2 FN1 MARK3 ZC3H13 SOCS6 ATF2 FAF1 SRSF12 KIAA1671 FRMD4A SF3B3 NKD2 CDCA7 RNPS1 MARK4 ANKRD34A FAM83G GNAS CAMSAP1 SRRM2 FRMD5 DNMT1 MAP3K2	3.55e-06	1248	156	26	int:YWHAG
Interaction	YWHAH interactions	NELFE SRRM1 SHROOM3 SORBS2 FN1 MARK3 ZC3H13 SOCS6 FAF1 SRSF12 KIAA1671 FRMD4A NKD2 CDCA7 CSNK1D KIAA1217 MARK4 FAM83G CAMSAP1 SRRM2 FRMD5 DNMT1 MAP3K2	1.35e-05	1102	156	23	int:YWHAH
GeneFamily	PDZ domain containing	SHROOM3 PCLO DVL3 ARHGEF11 PALS1 LRRC7	2.46e-04	152	104	6	1220
GeneFamily	SMAD family	SMAD1 SMAD3	8.97e-04	8	104	2	750
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	DOCK10 ARHGAP9 SPTBN4 SBF2 AGAP7P AGAP4	1.22e-03	206	104	6	682
GeneFamily	Doublecortin superfamily	DCLK3 RP1	1.43e-03	10	104	2	1369
Coexpression	PEREZ_TP53_TARGETS	SORBS2 PRR5L LPAR5 APC2 PHRF1 DVL3 MDM2 KIAA1671 LOXL1 KIAA1217 MARK4 FAM83G KCNS2 INAVA GNAS ASB2 FUT4 MUC2 CERS4 FRMD5 SMAD3 SHISA8 DNMT3B FAM149A	2.44e-07	1201	158	24	M4391
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	GALNT14 BNC2 SHROOM3 SORBS2 WWOX FAF1 KIAA1217 SBF2 NRG3	1.29e-06	176	158	9	M39223
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	KIF21A PCLO APC2 LPCAT4 NPAS3 LAMA5 CSMD3 SRSF12 PPARGC1A NRXN2 CASKIN1 SBF2 DCLK3 CACNA1G LRRC7 BSN SAMD14 MUC2 UNC79 FRMD5 MAP3K2	3.32e-06	1106	158	21	M39071
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	BNC2 KIF21A PCLO LPCAT4 NPAS3 CSMD3 SORCS1 PPARGC1A FRMD4A EML5 NRXN2 CACNA1G LRRC7 BSN UNC79 DYNC1I1	5.82e-06	703	158	16	M39070
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	GALNT14 BNC2 SHROOM3 WWOX FRMD4A NRG3	1.38e-05	86	158	6	M39248
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	GALNT14 BNC2 NPR1 SHROOM3 PRR5L FN1 GPR88 CHST8 STK32A PTPRB NKD2 CDCA7 KIAA1217 NGF INAVA GNAS FUT4 NRG3 PIK3R5	2.69e-05	1074	158	19	M1941
Coexpression	LAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX	SHROOM3 WWOX KIF21A FAF1 PPARGC1A KIAA1217 SBF2	3.94e-05	152	158	7	M39239
Coexpression	LIU_CDX2_TARGETS_UP	NPR1 MUC2 NOTCH4 DNMT3B	5.75e-05	35	158	4	M16637
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	GALNT14 BNC2 SORBS2 WWOX ZC3H13 PCLO SORCS1 SRRM2	6.13e-05	221	158	8	M39222
Coexpression	THEODOROU_MAMMARY_TUMORIGENESIS	NKD2 AGAP7P AGAP4 NOTCH4	7.19e-05	37	158	4	MM1121
Coexpression	DESCARTES_FETAL_MUSCLE_SCHWANN_CELLS	CSMD3 SORCS1 STK32A SEMA3B KIAA1755 FRMD5	7.50e-05	116	158	6	M40251
Coexpression	MIKKELSEN_MCV6_ICP_WITH_H3K27ME3	APC2 ARHGAP9 TBATA ASB2 FAM149A	9.17e-05	75	158	5	M1956
CoexpressionAtlas	FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000	BNC2 SHROOM3 SORBS2 KIF21A PCLO APC2 DOCK10 NPAS3 LAMA5 APOBR SRSF12 NGRN PPARGC1A CELSR1 EML5 ST8SIA6 LOXL1 KIAA1217 CACNA1G NRG3 FRMD5 DNMT3B	2.67e-06	973	156	22	Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#2	SORBS2 KIF21A PCLO APC2 NPAS3 NGRN PPARGC1A EML5 NRG3 FRMD5	3.61e-06	210	156	10	Facebase_RNAseq_e9.5_Olfactory Placode_1000_K2
CoexpressionAtlas	cerebral cortex	B3GNT4 SMIM13 KIF21A PCLO APC2 NPAS3 HSD11B1L GPR88 CSMD3 CHST8 SRSF12 SORCS1 SPTBN4 NRXN2 CASKIN1 ANKRD34A KCNS2 CACNA1G LRRC7 RND2 NRG3 BSN SAMD14 UNC79 DAGLA FRMD5 DYNC1I1	5.19e-06	1428	156	27	cerebral cortex
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000	BNC2 SHROOM3 SORBS2 KIF21A PCLO APC2 DOCK10 NPAS3 LAMA5 SRSF12 NGRN PPARGC1A CELSR1 EML5 ST8SIA6 LOXL1 CACNA1G NRG3 NIPBL FRMD5	3.66e-05	984	156	20	Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#2	SORBS2 KIF21A PCLO APC2 NPAS3 NGRN PPARGC1A EML5 NRG3 FRMD5	4.25e-05	279	156	10	Facebase_RNAseq_e10.5_Olfactory Pit_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2	SORBS2 KIF21A APC2 NPAS3 PPARGC1A EML5 NRXN2 NRG3 FRMD5	9.40e-05	248	156	9	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 PCLO CSMD3 SPTBN4 PPARGC1A FRMD4A LRRC7 NRG3 UNC79 DYNC1I1	2.96e-09	198	161	10	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALNT14 DOCK10 NPAS3 LAMA5 CSMD3 CIDEA STK32A NGF SHISA8	7.70e-09	161	161	9	3b5d7a3dab479c6959a428f3954dedd989900276
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 PCLO CSMD3 SPTBN4 FRMD4A LRRC7 NRG3 UNC79 DYNC1I1	4.24e-08	196	161	9	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 PCLO CSMD3 SPTBN4 FRMD4A LRRC7 NRG3 UNC79 DYNC1I1	4.63e-08	198	161	9	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 PCLO CSMD3 SPTBN4 FRMD4A LRRC7 NRG3 UNC79 DYNC1I1	4.63e-08	198	161	9	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	SORBS2 PCLO CSMD3 SPTBN4 FRMD4A LRRC7 NRG3 UNC79 DYNC1I1	5.04e-08	200	161	9	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 SORBS2 CELSR1 KIAA1217 INAVA RP1 CERS4 FAM149A	3.40e-07	182	161	8	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 DOCK10 SORCS1 NKD2 LRP1 NRG3 FRMD5 SMAD3	3.55e-07	183	161	8	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PCLO SRSF12 SPTBN4 ANKRD34A LRRC7 BSN UNC79 DYNC1I1	4.02e-07	186	161	8	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	droplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 PCLO NPAS3 KIAA1671 NRXN2 NGF SAMD14 SMAD1	4.18e-07	187	161	8	9c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 PCLO NPAS3 KIAA1671 NRXN2 NGF SAMD14 SMAD1	4.18e-07	187	161	8	9e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 SHROOM3 SORBS2 WWOX FAF1 SORCS1 SBF2 LARGE1	5.11e-07	192	161	8	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.31e-07	193	161	8	01c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.53e-07	194	161	8	3c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.53e-07	194	161	8	53a5e8863d79a052dff0758f389be5ac3883c721
ToppCell	Children_(3_yrs)-Endothelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 KIAA1671 PTPRB ST8SIA6 KIAA1217 NRG3 SMAD1 NOTCH4	5.74e-07	195	161	8	094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCell	PCW_13-14-Endothelial-Endothelial_mature\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.74e-07	195	161	8	31353269591c9eee84872838e91995d4a035da46
ToppCell	PCW_13-14-Endothelial\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.97e-07	196	161	8	7286de29a34e13834cd6347c67a1443897fa4ade
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.97e-07	196	161	8	29ed8b1c4cd730db8632fde6eece404f1883a86d
ToppCell	PCW_10-12-Endothelial-Endothelial_immature\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.97e-07	196	161	8	c65b8c7ea34a21897c390e6fb42ee8ca41e9c976
ToppCell	PCW_10-12-Endothelial-Endothelial_mature\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.97e-07	196	161	8	481d79bdaec069ad2746a28d39eeee8d3edf7305
ToppCell	PCW_13-14-Endothelial-Endothelial_immature\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.97e-07	196	161	8	9ed96085f0acce07bf2f8d4cc212cc50e613be0c
ToppCell	PCW_10-12-Endothelial\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.97e-07	196	161	8	2c60dcf9132ee156f25b349e2ac5313709def4f6
ToppCell	Endothelial\|World / Lineage, Cell type, age group and donor	FLT4 KIAA1671 PTPRB ST8SIA6 KIAA1217 NRG3 SMAD1 NOTCH4	5.97e-07	196	161	8	96c6d78482a130ce4e29f6629972a06d10d7530e
ToppCell	PCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating3_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	6.20e-07	197	161	8	aedc1e3ed6b558bf2f7649919f43049f8348ab85
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	6.45e-07	198	161	8	eac26ed95b4a4343a5dfe1fbecef9374e5947884
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCLO CSMD3 SPTBN4 FRMD4A GNAS NRG3 UNC79 DYNC1I1	6.45e-07	198	161	8	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	PCW_13-14-Endothelial-Endothelial_cycling\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	6.45e-07	198	161	8	8fb624407abb9cb711d8d8a8665014cf6e39559a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 PCLO CSMD3 SPTBN4 FRMD4A NRG3 UNC79 DYNC1I1	6.45e-07	198	161	8	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating3_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	6.45e-07	198	161	8	5fe186d46c47ea1ca450cf67e8eb01c2c3f7f83c
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	VASH1 BIRC6 PTPRB KIAA1217 DIAPH2 NIPBL SMAD1 NOTCH4	6.95e-07	200	161	8	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALNT14 CSMD3 CIDEA SORCS1 STK32A NGF SHISA8	2.58e-06	167	161	7	1c1b4722c6c0eff85a9b32ca7b4e281caebf63b0
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 LAMA5 RSPH6A KIAA1217 INAVA RP1 C13orf42	2.91e-06	170	161	7	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALNT14 DOCK10 NPAS3 CSMD3 CIDEA SORCS1 SHISA8	3.14e-06	172	161	7	7e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	FLT4 NPAS3 CHST8 KIAA1671 PTPRB DYNC1I1 SMAD1	3.26e-06	173	161	7	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TNFSF14 DOCK10 ARHGAP9 APOBR MAP4K1 LRP1 ASB2	3.26e-06	173	161	7	20f7dfe7d92a3dbec9da9a1f3185aa10cb8f0a3c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GALNT14 DOCK10 NPAS3 LAMA5 CSMD3 SORCS1 SHISA8	3.39e-06	174	161	7	a5f2a4e3b25e6084bd7003a53da86a44f6fcf294
ToppCell	Control-Neuronal_cells-Neuronal_cells\|Control / group, cell type (main and fine annotations)	FLT4 NPAS3 KIAA1671 PTPRB NRG3 DYNC1I1 SMAD1	3.65e-06	176	161	7	98c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell	Control-Neuronal_cells\|Control / group, cell type (main and fine annotations)	FLT4 NPAS3 KIAA1671 PTPRB NRG3 DYNC1I1 SMAD1	3.65e-06	176	161	7	c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PRSS56 DOCK10 SORCS1 SEMA3B KIAA1755 NRG3 FRMD5	4.39e-06	181	161	7	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PTPRB NKD2 NGF KIAA1755 LRRC7 ASB2 SMAD3	4.72e-06	183	161	7	e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNC2 FLT4 GPR88 PTPRB LOXL1 SEMA3B LRRC7	4.72e-06	183	161	7	ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLT4 PCLO NPAS3 KIAA1671 PTPRB NRG3 SMAD1	5.07e-06	185	161	7	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	SHROOM3 STK32A CELSR1 KIAA1217 RP1 FRMD5 FAM149A	5.07e-06	185	161	7	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 PCLO NPAS3 KIAA1671 PTPRB NRG3	5.07e-06	185	161	7	3be9e05b929ac4d956b1d53284072f668a6c1959
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 PCLO NPAS3 KIAA1671 PTPRB NRG3	5.07e-06	185	161	7	c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell	PCW_05-06-Neuronal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KIF21A PRSS56 DOCK10 SORCS1 EML5 KIAA1755 FRMD5	5.44e-06	187	161	7	03a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NOTCH4	5.44e-06	187	161	7	29b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NPR1 PIEZO1 VASH1 KIAA1671 PTPRB ST8SIA6 NOTCH4	5.44e-06	187	161	7	a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT4 PCLO NPAS3 KIAA1671 NRXN2 NGF SMAD1	5.64e-06	188	161	7	dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	5.64e-06	188	161	7	b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 NPAS3 KIAA1671 PTPRB NRG3 DYNC1I1 SMAD1	5.64e-06	188	161	7	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SHROOM3 SORBS2 STK32A CELSR1 KIAA1217 RP1 FRMD5	5.64e-06	188	161	7	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT4 PCLO NPAS3 KIAA1671 NRXN2 NGF SMAD1	5.64e-06	188	161	7	2ef08313087e91985bcffc46c3798470cdeec49c
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT4 PCLO NPAS3 KIAA1671 NRXN2 NGF SMAD1	5.64e-06	188	161	7	1f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 NPAS3 KIAA1671 PTPRB NRG3 DYNC1I1 SMAD1	6.04e-06	190	161	7	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NOTCH4	6.04e-06	190	161	7	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	SORBS2 KIF21A PPARGC1A MYPN LRRC7 FRMD5 LARGE1	6.25e-06	191	161	7	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 SORBS2 CELSR1 KIAA1217 RP1 CERS4 FAM149A	6.25e-06	191	161	7	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NOTCH4	6.25e-06	191	161	7	e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	6.47e-06	192	161	7	7dbe3117a0f58ff2e838963d49f788a59a4351d7
ToppCell	background-NK_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	BNC2 PRR5L DOCK10 ARHGAP9 APOBR ST8SIA6 SYTL1	6.69e-06	193	161	7	f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NOTCH4	6.69e-06	193	161	7	72d20ee257149b238016b44d183ce3fc24b8f621
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZC3H13 KIF21A SPTBN4 ANKRD34A NRG3 BSN DYNC1I1	6.69e-06	193	161	7	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 SORBS2 KIAA1671 PTPRB ST8SIA6 NRG3 C13orf42	6.69e-06	193	161	7	84d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	6.92e-06	194	161	7	8c88a0ddd61ad900426e312ca4ab13061c0380b8
ToppCell	PCW_05-06-Endothelial\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	6.92e-06	194	161	7	00291c62795a55a7e63b1db10c139d6a3298e55e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 FN1 NPAS3 PTPRB ST8SIA6 MARK4 NOTCH4	6.92e-06	194	161	7	b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LINC00473 FLT4 FN1 PTPRB ST8SIA6 MARK4 NOTCH4	6.92e-06	194	161	7	ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	SORBS2 KIF21A PPARGC1A MYPN ALPK3 DYNC1I1 LARGE1	7.16e-06	195	161	7	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	COPD-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	FLT4 FN1 NPAS3 FAF1 KIAA1671 DYNC1I1 SMAD1	7.16e-06	195	161	7	e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GALNT14 HIRIP3 LPAR5 PTCRA CHST8 NRXN2 SAMD14	7.16e-06	195	161	7	027075e9c62b5754a014a9d1393e1b0f5ae42e41
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Myeloid-Megakaryocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GALNT14 HIRIP3 LPAR5 PTCRA CHST8 NRXN2 SAMD14	7.16e-06	195	161	7	1bcc0c8b1281396b1433ce5a2ec8681de47ce9ad
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 CELSR1 KIAA1217 INAVA RP1 CERS4 FAM149A	7.16e-06	195	161	7	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature2_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 VASH1 KIAA1671 PTPRB ST8SIA6 NOTCH4	7.40e-06	196	161	7	b0288e28a6e6222a9e310eb6fe228c04b618db13
ToppCell	PCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	7.40e-06	196	161	7	b826dce5b3daa8eb3d4a530b9564de58d9ce3767
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LINC00473 FLT4 FN1 PTPRB ST8SIA6 MARK4 NOTCH4	7.40e-06	196	161	7	8f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LINC00473 FLT4 FN1 PTPRB ST8SIA6 MARK4 NOTCH4	7.40e-06	196	161	7	48b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCell	Fetal_29-31_weeks-Endothelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLT4 KIAA1671 PTPRB ST8SIA6 NRG3 SMAD1 NOTCH4	7.40e-06	196	161	7	3981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LINC00473 FLT4 FN1 PTPRB ST8SIA6 MARK4 NOTCH4	7.40e-06	196	161	7	473980c827443464d08a0be28c53e3536369b12a
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TNFSF14 ARHGAP9 CSMD3 SORCS1 CDCA7 BUB1B DNMT3B	7.40e-06	196	161	7	1cc2b11764584129703ec61965e8ec4e051464e7
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	7.65e-06	197	161	7	4e9221cb02122aed2981c3c9157e847a3710e323
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BNC2 FN1 DOCK10 LOXL1 SBF2 LRP1 DYNC1I1	7.65e-06	197	161	7	31a1852911bda38543916585fda34255fd62a134
ToppCell	background-NK_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BNC2 DOCK10 ARHGAP9 APOBR ST8SIA6 PPP1R18 SYTL1	7.65e-06	197	161	7	e8e1d3e557fe821efe81012e759e35e4ae33ce86
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	7.65e-06	197	161	7	21a1080e1db3a64f3eccc7aed2b3189332d31038
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NPR1 FLT4 FN1 PTPRB KIAA1217 ALPK3 NOTCH4	7.65e-06	197	161	7	4e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell	nucseq-Endothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLT4 KIAA1671 PTPRB ST8SIA6 KIAA1217 NRG3 NOTCH4	7.65e-06	197	161	7	ebf9be068eaa658493fa7884fd19f34642922acb
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_venous_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPR1 FLT4 KIAA1671 PTPRB ST8SIA6 NRG3 NOTCH4	7.65e-06	197	161	7	88859b7b24b36afab4a684fd7abf0e0f8e5b525c
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR1 FLT4 FN1 KIAA1671 PTPRB ALPK3 NOTCH4	8.17e-06	199	161	7	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	10x5'v1-week_14-16-Endothelial-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR1 FLT4 FN1 PTPRB KIAA1217 ALPK3 NOTCH4	8.45e-06	200	161	7	2488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SHROOM3 SORBS2 PCLO KIAA1671 CELSR1 KIAA1217 SYTL1	8.45e-06	200	161	7	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NPR1 VASH1 PTPRB KIAA1217 DIAPH2 SMAD1 NOTCH4	8.45e-06	200	161	7	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR1 FLT4 FN1 PTPRB KIAA1217 ALPK3 NOTCH4	8.45e-06	200	161	7	ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCell	10x5'v1-week_14-16-Endothelial\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR1 FLT4 FN1 PTPRB KIAA1217 ALPK3 NOTCH4	8.45e-06	200	161	7	e786544cf6f891550c4be55ebb4928c92297b504
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK10 NPAS3 LAMA5 SORCS1 NGF SHISA8	9.41e-06	134	161	6	d63fff23040eada31bc35ba1e05b7c6a663e0037
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-2\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	BNC2 NPR1 PIEZO1 MEI1 NLRP6 KCNS2	1.47e-05	145	161	6	f9aa7f2401e26f1e8cec1112a71c16e1c2784893
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma-2\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SPTBN4 CASKIN1 RND2 BSN USP27X UNC79	1.53e-05	146	161	6	bc2adef529d0bbfcccef7435401a47a6ffcc1832
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SPTBN4 CASKIN1 RND2 BSN USP27X UNC79	1.53e-05	146	161	6	72c1e7e0c2b6ff6c4084af61fa19c2b8eab16eda
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LPAR5 DOCK10 APOBR MAP4K1 ASB2 PIK3R5	1.66e-05	148	161	6	12fa2c4922f03803006c606b1b16e79441e3bb13
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PTCRA BUD13 SEMA3B ANKRD34A CACNA1G SMAD1	1.72e-05	149	161	6	13b445c13bb8f31ff0876addd1baf969ae220ea3
Disease	coronary artery disease	CYP1A1 SHROOM3 SORBS2 FN1 PTCRA RRP1B MARK3 BUD13 RSPH6A PTK7 SF3B3 LOXL1 KIAA1217 MARK4 LRP1 RPRD2 LRRC7 RP1 BSN SMAD3	5.33e-06	1194	156	20	EFO_0001645
Disease	pulse pressure measurement	BNC2 SHROOM3 FN1 MARK3 LAMA5 MEI1 RNF126 FAF1 SPTBN4 PPARGC1A CDCA7 LOXL1 KIAA1217 SBF2 MYPN LRP1 KIAA1755 CCDC157 SMAD3 DNMT1 DNMT3B	1.49e-05	1392	156	21	EFO_0005763
Disease	obsolete_red blood cell distribution width	PMS2P1 CYP1A1 LPAR5 MARK3 PIEZO1 BUD13 HSD11B1L BIRC6 FRMD4A NKD2 ST8SIA6 CDCA7 KIAA1217 MARK4 RP1 AGAP7P DAGLA CERS4 FRMD5 SMAD1	3.04e-05	1347	156	20	EFO_0005192
Disease	monocyte percentage of leukocytes	TNFSF14 MARK3 PIEZO1 DOCK10 ARHGAP9 C16orf96 MEI1 GPR88 ARHGEF11 NLRP6 CSNK1D MARK4 KIAA1755 PIK3R5	3.62e-05	731	156	14	EFO_0007989
Disease	cystatin C measurement	CYP1A1 BNC2 SHROOM3 ZNF337 CHST8 PPARGC1A KIAA1217 LRP1 GNAS BSN	5.92e-05	402	156	10	EFO_0004617
Disease	Abnormality of refraction	GALNT14 WWOX RRP1B PCLO PRSS56 PKD1L1 PHRF1 BIRC6 PPARGC1A LOXL1 DAGLA CERS4 DYNC1I1	6.36e-05	673	156	13	HP_0000539
Disease	endometriosis of uterus (is_marker_for)	DNMT1 DNMT3B	8.30e-05	3	156	2	DOID:288 (is_marker_for)
Disease	dimethylglycine measurement	GALNT14 ZC3H13 CSMD3 CACNA1G	1.03e-04	46	156	4	EFO_0010476
Disease	Centromeric instability of chromosomes 1,9 and 16 and immunodeficiency	CDCA7 DNMT3B	1.65e-04	4	156	2	cv:C0398788
Disease	Clear-cell metastatic renal cell carcinoma	FLT4 DNMT1	1.65e-04	4	156	2	C2931852
Disease	complex cortical dysplasia with other brain malformations (is_implicated_in)	APC2 CAMSAP1	1.65e-04	4	156	2	DOID:0090131 (is_implicated_in)
Disease	HSAN Type IV	NGF DNMT1	1.65e-04	4	156	2	C0020074
Disease	Hereditary Sensory Radicular Neuropathy	NGF DNMT1	1.65e-04	4	156	2	C0086405
Disease	congenital heart disease (biomarker_via_orthology)	DNMT1 DNMT3B	1.65e-04	4	156	2	DOID:1682 (biomarker_via_orthology)
Disease	Hereditary Sensory and Autonomic Neuropathies	NGF DNMT1	1.65e-04	4	156	2	C0027889
Disease	visual impairment and progressive phthisis bulbi (implicated_via_orthology)	MARK3 MARK4	1.65e-04	4	156	2	DOID:0070356 (implicated_via_orthology)
Disease	Metastatic melanoma	FLT4 STK32A MAP4K1 ALPK3	1.94e-04	54	156	4	C0278883
Disease	Hereditary Sensory Autonomic Neuropathy, Type 2	NGF DNMT1	2.75e-04	5	156	2	C0020072
Disease	Milroy Disease	FLT4 CELSR1	2.75e-04	5	156	2	C1704423
Disease	aspartate aminotransferase to alanine aminotransferase ratio	ARHGAP9 CPN1 PPARGC1A SF3B3 ST8SIA6 MARK4 RP1	2.93e-04	239	156	7	EFO_0010934
Disease	vital capacity	CYP1A1 BNC2 SHROOM3 WWOX FN1 LPAR5 ZNF337 PIEZO1 PCLO C16orf96 LOXL1 MYPN BOP1 RPRD2 DAGLA DYNC1I1 SMAD3	3.06e-04	1236	156	17	EFO_0004312
Disease	endometriosis (is_marker_for)	CYP1A1 DNMT1 DNMT3B	3.06e-04	25	156	3	DOID:289 (is_marker_for)
Disease	blood cadmium measurement	BNC2 WWOX SMAD3	3.45e-04	26	156	3	EFO_0007576
Disease	arterial stiffness measurement	BNC2 NPAS3 RSPH6A RNF126	3.73e-04	64	156	4	EFO_0004517
Disease	Sensory Neuropathy, Hereditary	NGF DNMT1	4.11e-04	6	156	2	C0699739
Disease	uric acid measurement	SHROOM3 FLT4 BIRC6 QRICH2 FAF1 PPP2R5B NRXN2 SBF2 MARK4 GNAS CERS4	4.21e-04	610	156	11	EFO_0004761
Disease	hereditary lymphedema (is_implicated_in)	PIEZO1 CELSR1	5.73e-04	7	156	2	DOID:0050580 (is_implicated_in)
Disease	Hereditary Sensory Autonomic Neuropathy, Type 5	NGF DNMT1	5.73e-04	7	156	2	C0020075
Disease	Malignant neoplasm of breast	CYP1A1 WWOX FN1 APC2 DVL3 MDM2 ATF2 SORCS1 CSNK1D ANKRD34A LRRC7 NIPBL NOTCH4 DNMT1 DNMT3B	5.98e-04	1074	156	15	C0006142
Disease	eosinophil percentage of leukocytes	BNC2 WWOX BUD13 C16orf96 RSPH6A CELSR1 SBF2 MARK4 ASB2 MUC2 PIK3R5 SMAD3	6.39e-04	746	156	12	EFO_0007991
Disease	Large cell carcinoma of lung	ALPK3 DCLK3 MAP3K2	6.42e-04	32	156	3	C0345958
Disease	joint hypermobility measurement	PIEZO1 LOXL1 NOTCH4	7.04e-04	33	156	3	EFO_0007905
Disease	autosomal dominant compelling helio-ophthalmic outburst syndrome	PRR5L BRWD3 KIAA1755 NRG3	7.54e-04	77	156	4	EFO_0007887
Disease	Hereditary Sensory Autonomic Neuropathy, Type 1	NGF DNMT1	7.62e-04	8	156	2	C0020071
Disease	sarcoma (is_implicated_in)	MDM2 PTPRB	7.62e-04	8	156	2	DOID:1115 (is_implicated_in)
Disease	otosclerosis	MARK3 ALPK3 SMAD3 DNMT1	9.12e-04	81	156	4	EFO_0004213
Disease	urate measurement	CYP1A1 BNC2 MARK3 BIRC6 QRICH2 FAF1 NRXN2 ALDH16A1 SBF2 LRP1 GNAS CERS4 LARGE1	9.77e-04	895	156	13	EFO_0004531
Disease	cerebral palsy (implicated_via_orthology)	AGAP7P AGAP4	1.22e-03	10	156	2	DOID:1969 (implicated_via_orthology)
Disease	nasopharyngeal neoplasm	FLT4 PCLO ZNF507 NRG3 SMAD3	1.28e-03	151	156	5	EFO_0004252
Disease	beta-nerve growth factor measurement	CHST8 ST8SIA6 NOTCH4	1.43e-03	42	156	3	EFO_0008035
Disease	major depressive disorder	BNC2 MARK3 PCLO BSN DAGLA	1.43e-03	155	156	5	MONDO_0002009
Disease	Craniofacial Abnormalities	BNC2 MBTPS1 NIPBL SMAD3 DNMT3B	1.47e-03	156	156	5	C0376634
Disease	Adenocarcinoma of large intestine	MDM2 PTK7 MARK4 DCLK3	1.71e-03	96	156	4	C1319315
Disease	thyroid stimulating hormone measurement	WWOX FAF1 PPARGC1A KIAA1217 MARK4 GNAS CERS4	1.71e-03	323	156	7	EFO_0004748
Disease	thyroid gland carcinoma (is_marker_for)	FLT4 PTPRB	1.77e-03	12	156	2	DOID:3963 (is_marker_for)
Disease	heart rate variability measurement, response to antipsychotic drug	PRSS56 ARHGAP9 SF3B3	1.86e-03	46	156	3	EFO_0008003, GO_0097332
Disease	Mammary Carcinoma, Human	CYP1A1 WWOX FN1 APC2 MDM2 ANKRD34A NOTCH4 DNMT1 DNMT3B	1.98e-03	525	156	9	C4704874
Disease	Mammary Neoplasms, Human	CYP1A1 WWOX FN1 APC2 MDM2 ANKRD34A NOTCH4 DNMT1 DNMT3B	1.98e-03	525	156	9	C1257931
Disease	Mammary Neoplasms	CYP1A1 WWOX FN1 APC2 MDM2 ANKRD34A NOTCH4 DNMT1 DNMT3B	2.03e-03	527	156	9	C1458155
Disease	anthropometric measurement	BNC2 FN1 LOXL1 BSN DYNC1I1	2.04e-03	168	156	5	EFO_0004302
Disease	esophageal cancer (is_implicated_in)	CYP1A1 WWOX	2.08e-03	13	156	2	DOID:5041 (is_implicated_in)
Disease	colitis (implicated_via_orthology)	PPARGC1A MUC2	2.08e-03	13	156	2	DOID:0060180 (implicated_via_orthology)
Disease	Leber congenital amaurosis (implicated_via_orthology)	WWOX PALS1	2.08e-03	13	156	2	DOID:14791 (implicated_via_orthology)
Disease	suntan	BNC2 CENPBD1P KIAA1217 DNMT3B	2.21e-03	103	156	4	EFO_0004279
Disease	acute myeloid leukemia (is_marker_for)	MDM2 DNMT1 DNMT3B	2.23e-03	49	156	3	DOID:9119 (is_marker_for)
Disease	Breast Carcinoma	CYP1A1 WWOX FN1 APC2 MDM2 ANKRD34A NOTCH4 DNMT1 DNMT3B	2.34e-03	538	156	9	C0678222
Disease	Crohn Disease	FN1 MUC2 SMAD3	2.37e-03	50	156	3	C0010346
Disease	diffuse plaque measurement	GALNT14 SHROOM3 PRR5L NPAS3 C1orf167 CSMD3 PPARGC1A FRMD4A NRG3 CERS4 NOTCH4	2.41e-03	758	156	11	EFO_0010699
Disease	creatinine measurement	CYP1A1 SHROOM3 LAMA5 BIRC6 BRWD3 PPARGC1A NRXN2 MYPN KIAA1755 GNAS BSN SMAD3 SHISA8	2.49e-03	995	156	13	EFO_0004518
Disease	urinary bladder cancer (is_marker_for)	CYP1A1 FN1 MDM2 DNMT1	2.54e-03	107	156	4	DOID:11054 (is_marker_for)
Disease	3-hydroxy-1-methylpropylmercapturic acid measurement	WWOX LAMA5 SORCS1 CSNK1D KIAA1217 ALPK3 ASB2	2.77e-03	352	156	7	EFO_0007015
Disease	Situs ambiguus	SHROOM3 PKD1L1	2.79e-03	15	156	2	C0266642
Disease	coffee consumption measurement	CYP1A1 NPAS3 BIRC6 PPARGC1A MYPN	2.88e-03	182	156	5	EFO_0006781
Disease	hair morphology measurement	WWOX FRMD4A NRG3	2.95e-03	54	156	3	EFO_0007821
Disease	diastolic blood pressure, systolic blood pressure	BNC2 ARHGAP9 C16orf96 PLPP6 PTK7 KIAA1671 PPARGC1A LOXL1 LRP1 SMAD3	3.09e-03	670	156	10	EFO_0006335, EFO_0006336
Disease	neutrophil collagenase measurement	NELFE CPN1	3.17e-03	16	156	2	EFO_0008248
Disease	idiopathic scoliosis (implicated_via_orthology)	MBTPS1 PTK7	3.17e-03	16	156	2	DOID:0060250 (implicated_via_orthology)
Disease	aspartate aminotransferase measurement	SHROOM3 MARK3 PIEZO1 BUD13 ARHGAP9 CPN1 BIRC6 PPARGC1A ST8SIA6 MYPN NGF NOTCH4	3.20e-03	904	156	12	EFO_0004736
Disease	Alzheimer's disease (implicated_via_orthology)	PPARGC1A LRP1 NOTCH4	3.44e-03	57	156	3	DOID:10652 (implicated_via_orthology)
Disease	Cocaine-Related Disorders	NGF LRRC7 SMAD1 SMAD3	3.51e-03	117	156	4	C0236736
Disease	spinal stenosis	DYNC1I1 SMAD3	3.59e-03	17	156	2	EFO_0007490
Disease	Cannabis use initiation	WWOX LRRC7	4.02e-03	18	156	2	EFO_0007586
Disease	level of Phosphatidylcholine (15:0_18:2) in blood serum	BUD13 DAGLA	4.02e-03	18	156	2	OBA_2045065
Disease	pancreatic ductal carcinoma (is_marker_for)	MDM2 DNMT1 DNMT3B	4.17e-03	61	156	3	DOID:3587 (is_marker_for)
Disease	serum albumin measurement	SHROOM3 FLT4 ALDH16A1 SBF2 ASB2 BSN DAGLA FRMD5 NOTCH4	4.38e-03	592	156	9	EFO_0004535
Disease	glomerulonephritis (is_marker_for)	FN1 NGF	4.48e-03	19	156	2	DOID:2921 (is_marker_for)
Disease	hemifacial microsomia	SHROOM3 FRMD4A	4.48e-03	19	156	2	MONDO_0015398
Disease	Cocaine Abuse	NGF LRRC7 SMAD1 SMAD3	4.70e-03	127	156	4	C0009171
Disease	cholangiocarcinoma (is_marker_for)	PRSS56 MDM2 MUC2	4.77e-03	64	156	3	DOID:4947 (is_marker_for)
Disease	transient cerebral ischemia (implicated_via_orthology)	MDM2 ATF2 MAP4K1	4.77e-03	64	156	3	DOID:224 (implicated_via_orthology)
Disease	Malignant Neoplasms	MDM2 BIRC6 ATF2 GNAS	4.83e-03	128	156	4	C0006826
Disease	colorectal cancer	WWOX LAMA5 SBF2 LRP1 GNAS NRG3 CAMSAP1 NOTCH4 SMAD3	4.98e-03	604	156	9	MONDO_0005575

Protein segments in the cluster

Peptide	Gene	Start	Entry
GRSLEHRPRGNTASL	BUB1B	316	O60566
LRRARPRRSHSSSQF	PPP2R5B	36	Q15173
LSRRRSQSPFRRSHG	BOP1	566	Q14137
RERTPRGPSERTRHN	C2orf16	1546	Q68DN1
HRSPSERSQRSSLER	C2orf16	1566	Q68DN1
ERSQRSSLERRHHSP	C2orf16	1571	Q68DN1
SERRHRSPSQRSHRG	C2orf16	1666	Q68DN1
RSPSQRSHRGPSERS	C2orf16	1671	Q68DN1
SLLERSHRSPSERRS	C2orf16	1816	Q68DN1
ASSRQSRPRVRSASL	GNAS	191	P84996
GIHRSLGTRLSRVRS	AGAP4	481	Q96P64
PRRVHNNSPDTSRRT	BUD13	241	Q9BRD0
HQRLAARSPRRGAAS	C1orf167	1416	Q5SNV9
DGPRSRVAGRLTNRH	CERS4	376	Q9HA82
RLHRPRDASTLGLSQ	BIRC6	3281	Q9NR09
DTQSTRRRPRHAEQI	CSMD3	421	Q7Z407
RQTIRHSTREKDRGP	DNMT1	601	P26358
VSSRERHRPSPRSTR	DNMT3B	111	Q9UBC3
ARSSRPIRDSSGNLH	ALDH16A1	541	Q8IZ83
AFPSRRSRDRHSANI	BNC2	871	Q6ZN30
SRTRIRRSGVSPLHL	ASB2	361	Q96Q27
RRSGVSPLHLAAERN	ASB2	366	Q96Q27
ARRRHGTRDSTLQGQ	ALPK3	731	Q96L96
SHAGIRLREARPSNT	ARHGEF11	481	O15085
RRSTEHRTVGTQRRL	C13orf42	226	A0A1B0GVH6
SSSPNIRLRRHSSQI	BRWD3	691	Q6RI45
HTTPQTQSTSGRRRR	ATF2	331	P15336
SAPTALSRRLRARTH	CELSR1	96	Q9NYQ6
EPSSLERHLRSAGSR	NPR1	516	P16066
AVRSSTSRPRQPEHR	HSD11B1L	221	Q7Z5J1
PLERSRSRHNGAISS	DIAPH2	1086	O60879
DHTTRSSLRGPRERA	DVL3	606	Q92997
LGRQHLPSSRTGRTL	CCDC157	651	Q569K6
RHRSNSLTRVDGQPR	CAMSAP1	441	Q5T5Y3
NGLTLTGRPRLSRRH	ANKRD34A	276	Q69YU3
HRSREKLTSTQPRRN	QRICH2	176	Q9H0J4
IGRSRRPRLSDRSHL	CYP1A1	351	P04798
SHRLRQSPSGTRLRR	NIBAN3	406	Q86XR2
HRVPIRASPRSTTAR	NRG3	171	P56975
TTRRHLSSRNRPEGK	POLDIP2	46	Q9Y2S7
RRGRHEQSPTSRPRK	C22orf15	131	Q8WYQ4
QRRVGRSHSVRAPAG	CASKIN1	911	Q8WXD9
SPATTTRLRALGSHR	PTCRA	181	Q6ISU1
VSHGRERPSARLSIR	PTPRB	1646	P23467
RQLSLAQGRAPSHRR	LARGE1	81	O95461
ALHPRRAQRRLSGLS	GPR88	271	Q9GZN0
RGRPDLSTLTHSIVR	HIRIP3	16	Q9BW71
RAPISHSLRRSRFSE	KIAA1671	1656	Q9BY89
NTLRGLGTPHRARTS	LPAR5	306	Q9H1C0
QAILVSRHDPASRRR	LPCAT4	166	Q643R3
QHSLDTALRRARSAP	NGF	41	P01138
SDTHRTNTPRRRKGR	NGRN	196	Q9NPE2
SPPRSRSRDRSHERN	NELFE	181	P18615
ATGRHSSRRLLRAIP	MBTPS1	176	Q14703
RRRHGFTVRSKDSLP	FAM149A	196	A5PLN7
RTDRSQRHLSRSPGI	SBF2	1676	Q86WG5
STSSHGRRPLIRQDR	LRRC7	801	Q96NW7
KTSRVSPGDQRRLHR	KIAA1755	986	Q5JYT7
TAPFHSRASGERQRR	FUT4	81	P22083
TTSNRHRRQIDRGVT	LRP1	3936	Q07954
PALRVRTARSDAGHR	EZHIP	321	Q86X51
RRSHGSPRRRQAPSL	LOXL1	86	Q08397
VRRRRSRLPRHSDSG	BSN	2626	Q9UPA5
RSHRRTPVQRTPLSA	DYNC1I1	371	O14576
HSRAPSPRLRSRLFS	DCLK3	31	Q9C098
STRPTRIESQHGIER	PCLO	3841	Q9Y6V0
LPTGTSRRARRSPRH	MUC2	5161	Q02817
QDPVSLRRGSHRLGS	EPS8L3	406	Q8TE67
REERLRHSRNPATRG	CSNK1D	311	P48730
RSHTLLRFPETRLGR	KCNS2	31	Q9ULS6
RARRTQGTSLRSPVS	MAP3K2	286	Q9Y2U5
RRPETLRSSSRNEHG	NIPBL	841	Q6KC79
SRRSHRLPTRSLGTV	MRGPRD	281	Q8TDS7
SRIARTLGLRRPVHS	PHRF1	391	Q9P1Y6
THRVVELRPPSRSRS	PHRF1	981	Q9P1Y6
LGIHARPRRRATTSL	PMS2P1	101	A4D2B8
TARKASRRSRQPARH	LAMA5	3311	O15230
QRRTITHSRLGNSSR	PRSS54	316	Q6PEW0
ADRRLSAHVRRPSTD	NKD2	211	Q969F2
RRQVAGHTRGPRLSL	SMPD4	796	Q9NXE4
LLSRRPLGHASSRDS	MEI1	476	Q5TIA1
SGPTYTLARRHSRVR	PRR5L	231	Q6MZQ0
RISSNRAIPDTRHLR	GALNT14	86	Q96FL9
RTHRNSPLYVRSRSR	PPARGC1A	611	Q9UBK2
RFASAVPHTTRSRRD	PALS1	506	Q8N3R9
TRRGRSPTLRDSTTQ	NRXN2	331	P58401
SLTSRPSTRGLTHLR	FAM189B	11	P81408
RRLERGTRPHSLSLN	FAM189B	646	P81408
DPRRASVTRRTFGHS	FRMD4A	276	Q9P2Q2
LSSVPRTRRRAVHIS	FRMD5	361	Q7Z6J6
THRRTSAIPRAFTRE	APC2	1526	O95996
EHRVRGVRRTASTPT	CPN1	231	P15169
RSLLRPGQAAELRHS	DOCK10	11	Q96BY6
SQPGHVERRAAIRST	B3GNT4	126	Q9C0J1
ERTRQRNPSDRHVIS	CIBAR1	131	A1XBS5
QHSDLRDPHSRRQRS	CACNA1G	701	O43497
GSTRLSRAPHIESRV	C16orf96	1116	A6NNT2
RHRTERSQERGSTPR	LINC00473	21	A8K010
RPREDRVPHSRNSIT	FN1	1491	P02751
GIHRSLGTRLSRVRS	AGAP7P	481	Q5VUJ5
HRAASSPGRTRRAIA	GPR142	266	Q7Z601
STLQFGRRLRRRTSH	MAN2B2	561	Q9Y2E5
SRSTFHGQPRERRTA	MARK3	561	P27448
RSRLARGSTIRSTFH	MARK4	556	Q96L34
RSIRGSPSLHAVLER	DAGLA	801	Q9Y4D2
SKRRERAPGNSIRLH	EML5	666	Q05BV3
HRLTVGRRSSPAQTR	FAF1	261	Q9UNN5
ETHTTRQPLRLRGSA	FAM27D1	136	Q5T7N8
RRSGHTFTVNPRRSV	PPP1R18	466	Q6NYC8
PSHRDTISRSGIILR	RPRD2	1401	Q5VT52
ARLRSTRPHSLDRQG	INAVA	596	Q3KP66
GRTRTEAHTALSRLR	PKD1L1	2446	Q8TDX9
PGRARRSDTHTFNRL	NLRP6	171	P59044
RRPSTANVTRAHGRI	PRSS56	91	P0CW18
RNISTPRGRHSITRL	RP1	81	P56715
RRQLSAPHITRGTFV	FAM83G	646	A6ND36
RRIRSTHRSSSLGIP	MAP4K1	316	Q92918
PGRRTSQASQRRHSR	RSPH6A	16	Q9H0K4
RTRVVRRSLSPVFNH	SYTL1	461	Q8IYJ3
ASHTLPALATRRVAR	HHLA1	301	C9JL84
SGSPSPSRRRHDNRR	RNPS1	121	Q15287
EGANSHTTLPQRRRL	RRP1B	556	Q14684
SLVRRGRSHSRTPQR	SRRM2	706	Q9UQ35
ATHRRSRSRTPLISR	SRRM2	1871	Q9UQ35
VARPRRSRGSENSHS	HOATZ	66	Q6PI97
HLVSRPSTSSRRRAI	MDM2	151	Q00987
QPRARLTTRRATGRH	RNF126	126	Q9BV68
TSSSPHRIRSARQRR	SMIM13	66	P0DJ93
SRGSRTRASLPVVRS	KIAA1217	161	Q5T5P2
REATHGTPAALRTLR	ST8SIA6	41	P61647
SLRRHSSLELGRGTQ	SHROOM3	671	Q8TF72
LGLERAHSPRARRTV	SHISA8	161	B8ZZ34
AHSPRARRTVTRALT	SHISA8	166	B8ZZ34
LIPASTRAVGRRRSH	TBATA	191	Q96M53
GRRHRPSRSRLRDSA	SAMD14	41	Q8IZD0
RLRLRVSLSHGRTVP	NPAS3	291	Q8IXF0
LLRGRRPYHIRSSTS	STK32A	216	Q8WU08
GFTRRPRTQSAPHRR	NOTCH4	1486	Q99466
RRRFERAIGPSQTHT	PRG4	1301	Q92954
RNSSLRALRRSPLHQ	SORBS2	771	O94875
PSDHRRSRSPSQRRT	SRSF12	106	Q8WXF0
TIPRSLDGRLQVSHR	SMAD1	66	Q15797
ATPLRASRLTRHRSA	CENPBD1P	71	B2RD01
RVHLSRSSSQRRSRP	APOBR	1001	Q0VD83
SRRSRSSVTLPHIIR	CDCA7	226	Q9BWT1
PFRVSNHDRSSRRGV	CIDEA	36	O60543
SSRRAVTPRHVSRIF	CHST8	171	Q9H2A9
SLGRGHRQLRRTDSR	RND2	181	P52198
GHNPRRRRITSSFTI	USP27X	61	A6NNY8
RAEQGLPIRSHRSST	PIK3R5	146	Q8WYR1
QTDIPFTRLGRSHRR	TNFSF14	16	O43557
LSEVHRSSRRGIINP	KIF21A	1311	Q7Z4S6
TIPRSLDGRLQVSHR	SMAD3	66	P84022
LESRRKGRNRRTHAP	SEMA3B	721	Q13214
EVGRRRRHSPSRSAS	SRRM1	516	Q8IYB3
VAVTRAHPDSQGRRR	FLT4	1306	P35916
ELHRRLSPRGVTSNA	WWOX	306	Q9NZC7
ASSRRLARQHRALTG	SPTBN4	806	Q9H254
LSSRRNVLHIRTIPG	ARHGAP9	396	Q9BRR9
PRSSLRVLRHGLEVS	SF3B3	431	Q15393
ARLRASESPVHRRGS	PLPP6	56	Q8IY26
SSPQLAASLRHRGRE	nan	111	Q86TA4
RSSPPRAAGHRSRKR	nan	206	A8MV72
GRRRTNSESLRLHSL	ZNF507	481	Q8TCN5
RSSPPRAAGHRSRKR	nan	236	A8MUA0
PARHRRKRRSTPLTS	ZNF212	6	Q9UDV6
HELTGQSSVLRRPVR	PIEZO1	386	Q92508
RALGSTSRPHFRRAS	PSMD8	31	P48556
TQPGDSSLRLQRARH	SORCS1	1136	Q8WY21
SPHRRNSRSERRPSG	VASH1	331	Q7L8A9
ITNRSRPPHLRRATV	PTK7	266	Q13308
VRAQRPIRSTSLRSH	SOCS6	116	O14544
RRSSPESDRQVHSRS	ZC3H13	1276	Q5T200
PLRHAVSSRRRNSVV	ZNF337	136	Q9Y3M9
RRVSVASDPGRRVQH	UNC79	736	Q9P2D8
IRSRLTSAGQSHRGR	MYPN	1041	Q86TC9