Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	2.18e-05	5	30	2	GO:0061628
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1 TAF1L	7.80e-05	9	30	2	GO:0001181
GeneOntologyMolecularFunction	microtubule motor activity	KIF12 DNHD1 DNAH17	1.57e-04	70	30	3	GO:0003777
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH17	3.29e-04	18	30	2	GO:0008569
GeneOntologyMolecularFunction	RNA polymerase II core promoter sequence-specific DNA binding	TAF1 TAF1L	6.41e-04	25	30	2	GO:0000979
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF12 DNHD1 DNAH17	7.27e-04	118	30	3	GO:0003774
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor binding	TAF1 TAF1L	7.48e-04	27	30	2	GO:0001091
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DNAH17	8.05e-04	28	30	2	GO:0051959
GeneOntologyMolecularFunction	lysine-acetylated histone binding	TAF1 TAF1L	9.25e-04	30	30	2	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	TAF1 TAF1L	9.88e-04	31	30	2	GO:0140033
GeneOntologyMolecularFunction	TBP-class protein binding	TAF1 TAF1L	1.12e-03	33	30	2	GO:0017025
GeneOntologyMolecularFunction	transcription regulator inhibitor activity	TAF1 TAF1L	1.33e-03	36	30	2	GO:0140416
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme activity	TAF1 TAF1L	1.41e-03	37	30	2	GO:0061631
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH17	1.41e-03	37	30	2	GO:0045505
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme activity	TAF1 TAF1L	1.90e-03	43	30	2	GO:0061650
GeneOntologyMolecularFunction	ATP-dependent activity	KIF12 DNHD1 HYOU1 ABCA7 DNAH17	2.04e-03	614	30	5	GO:0140657
GeneOntologyMolecularFunction	histone acetyltransferase activity	TAF1 TAF1L	2.66e-03	51	30	2	GO:0004402
GeneOntologyMolecularFunction	nuclear receptor binding	NCOR1 TAF1 TAF1L	2.72e-03	187	30	3	GO:0016922
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor activity	TAF1 TAF1L	2.76e-03	52	30	2	GO:0016251
GeneOntologyMolecularFunction	core promoter sequence-specific DNA binding	TAF1 TAF1L	3.08e-03	55	30	2	GO:0001046
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	TAF1 TAF1L	3.08e-03	55	30	2	GO:0061733
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	TAF1 TAF1L	3.66e-03	60	30	2	GO:0034212
GeneOntologyMolecularFunction	general transcription initiation factor binding	TAF1 TAF1L	4.15e-03	64	30	2	GO:0140296
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	TAF1 TAF1L	4.41e-03	66	30	2	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	TAF1 TAF1L	4.41e-03	66	30	2	GO:0001098
GeneOntologyMolecularFunction	general transcription initiation factor activity	TAF1 TAF1L	4.67e-03	68	30	2	GO:0140223
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	ABHD4 TAF1 TAF1L	5.35e-03	238	30	3	GO:0016747
GeneOntologyMolecularFunction	p53 binding	TAF1 TAF1L	5.95e-03	77	30	2	GO:0002039
GeneOntologyMolecularFunction	N-acetyltransferase activity	TAF1 TAF1L	6.10e-03	78	30	2	GO:0008080
GeneOntologyMolecularFunction	promoter-specific chromatin binding	TAF1 TAF1L	6.89e-03	83	30	2	GO:1990841
GeneOntologyMolecularFunction	methylated histone binding	TAF1 TAF1L	7.37e-03	86	30	2	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	TAF1 TAF1L	7.71e-03	88	30	2	GO:0140034
GeneOntologyMolecularFunction	N-acyltransferase activity	TAF1 TAF1L	1.02e-02	102	30	2	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	TAF1 TAF1L	1.06e-02	104	30	2	GO:0016407
GeneOntologyCellularComponent	microtubule associated complex	KIF12 DNHD1 INCENP DNAH17	9.07e-05	161	31	4	GO:0005875
GeneOntologyCellularComponent	sperm flagellum	DNHD1 QRICH2 IFT172 DNAH17	2.71e-04	214	31	4	GO:0036126
GeneOntologyCellularComponent	lateral element	KASH5 INCENP	3.58e-04	19	31	2	GO:0000800
GeneOntologyCellularComponent	meiotic spindle	KASH5 INCENP	3.58e-04	19	31	2	GO:0072687
GeneOntologyCellularComponent	9+2 motile cilium	DNHD1 QRICH2 IFT172 DNAH17	4.05e-04	238	31	4	GO:0097729
GeneOntologyCellularComponent	axonemal dynein complex	DNHD1 DNAH17	6.25e-04	25	31	2	GO:0005858
GeneOntologyCellularComponent	pronucleus	TAF1 TAF1L	7.85e-04	28	31	2	GO:0045120
GeneOntologyCellularComponent	MLL1 complex	TAF1 TAF1L	1.03e-03	32	31	2	GO:0071339
GeneOntologyCellularComponent	MLL1/2 complex	TAF1 TAF1L	1.09e-03	33	31	2	GO:0044665
GeneOntologyCellularComponent	motile cilium	DNHD1 QRICH2 IFT172 DNAH17	1.79e-03	355	31	4	GO:0031514
GeneOntologyCellularComponent	synaptonemal complex	KASH5 INCENP	2.12e-03	46	31	2	GO:0000795
GeneOntologyCellularComponent	synaptonemal structure	KASH5 INCENP	2.12e-03	46	31	2	GO:0099086
GeneOntologyCellularComponent	transcription factor TFIID complex	TAF1 TAF1L	2.21e-03	47	31	2	GO:0005669
GeneOntologyCellularComponent	dynein complex	DNHD1 DNAH17	2.90e-03	54	31	2	GO:0030286
GeneOntologyCellularComponent	axoneme	DNHD1 IFT172 DNAH17	3.51e-03	207	31	3	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	DNHD1 IFT172 DNAH17	3.55e-03	208	31	3	GO:0097014
GeneOntologyCellularComponent	histone methyltransferase complex	TAF1 TAF1L	5.52e-03	75	31	2	GO:0035097
HumanPheno	Absent sperm flagella	DNHD1 QRICH2 DNAH17	4.10e-05	28	13	3	HP:0032558
HumanPheno	Coiled sperm flagella	DNHD1 QRICH2 DNAH17	6.17e-05	32	13	3	HP:0032560
HumanPheno	Short sperm flagella	DNHD1 QRICH2 DNAH17	6.78e-05	33	13	3	HP:0032559
HumanPheno	Abnormal sperm tail morphology	DNHD1 QRICH2 DNAH17	1.51e-04	43	13	3	HP:0012868
Domain	TAF_II_230-bd	TAF1 TAF1L	2.49e-06	2	30	2	IPR009067
Domain	DUF3591	TAF1 TAF1L	2.49e-06	2	30	2	PF12157
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	2.49e-06	2	30	2	IPR022591
Domain	-	TAF1 TAF1L	2.49e-06	2	30	2	1.10.1100.10
Domain	TBP-binding	TAF1 TAF1L	2.49e-06	2	30	2	PF09247
Domain	TAF1_animal	TAF1 TAF1L	2.49e-06	2	30	2	IPR011177
Domain	Bromodomain_CS	TAF1 TAF1L	7.91e-04	26	30	2	IPR018359
Domain	BROMODOMAIN_1	TAF1 TAF1L	1.60e-03	37	30	2	PS00633
Domain	Bromodomain	TAF1 TAF1L	1.69e-03	38	30	2	PF00439
Domain	BROMODOMAIN_2	TAF1 TAF1L	1.97e-03	41	30	2	PS50014
Domain	BROMO	TAF1 TAF1L	2.06e-03	42	30	2	SM00297
Domain	Bromodomain	TAF1 TAF1L	2.06e-03	42	30	2	IPR001487
Domain	-	TAF1 TAF1L	2.06e-03	42	30	2	1.20.920.10
Domain	PH	RAPH1 PREX1 DOCK9	5.79e-03	229	30	3	PF00169
Pathway	WP_MECP2_AND_ASSOCIATED_RETT_SYNDROME	NCOR1 TAF1 TAF1L	3.04e-05	46	19	3	MM15949
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	8.20e-07	2	32	2	38804708
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	8.20e-07	2	32	2	10070062
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	8.20e-07	2	32	2	22842574
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	8.20e-07	2	32	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	8.20e-07	2	32	2	34403156
Pubmed	TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.	TAF1 TAF1L	2.46e-06	3	32	2	11592977
Pubmed	Regulated expression of TAF1 in 1-cell mouse embryos.	TAF1 TAF1L	2.46e-06	3	32	2	16822332
Pubmed	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.	TAF1 TAF1L	2.46e-06	3	32	2	12217962
Pubmed	TAF7: a possible transcription initiation check-point regulator.	TAF1 TAF1L	2.46e-06	3	32	2	16407123
Pubmed	Apaf-1 deficiency and neural tube closure defects are found in fog mice.	ABCA7 APAF1	2.46e-06	3	32	2	11504943
Pubmed	Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.	TAF1 TAF1L	1.23e-05	6	32	2	19959467
Pubmed	Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.	TAF1 TAF1L	2.29e-05	8	32	2	2034279
Pubmed	Genetic mapping in the region of the mouse X-inactivation center.	TAF1 TAF1L	2.29e-05	8	32	2	1974879
Pubmed	Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice.	TAF1 TAF1L	2.29e-05	8	32	2	31012985
Pubmed	Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.	TAF1 TAF1L	2.29e-05	8	32	2	8468051
Pubmed	High-density molecular map of the central span of the mouse X chromosome.	TAF1 TAF1L	2.29e-05	8	32	2	1675191
Pubmed	Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.	TAF1 TAF1L	2.94e-05	9	32	2	7874112
Pubmed	The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.	TAF1 TAF1L	2.94e-05	9	32	2	12665565
Pubmed	HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes.	TAF1 TAF1L	2.94e-05	9	32	2	9751712
Pubmed	Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.	TAF1 TAF1L	3.67e-05	10	32	2	2055107
Pubmed	Characterization of a murine gene expressed from the inactive X chromosome.	TAF1 TAF1L	4.49e-05	11	32	2	2034278
Pubmed	The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.	TAF1 TAF1L	6.36e-05	13	32	2	7805729
Pubmed	Mapping of loci and translocation breakpoints in Xq13: isolation of a conserved locus that maps close to CCG1 in human and mouse.	TAF1 TAF1L	6.36e-05	13	32	2	8012115
Pubmed	Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.	TAF1 TAF1L	6.36e-05	13	32	2	11557891
Pubmed	Rps4 maps near the inactivation center on the mouse X chromosome.	TAF1 TAF1L	6.36e-05	13	32	2	1740345
Pubmed	XIST and the mapping of the X chromosome inactivation centre.	TAF1 TAF1L	6.36e-05	13	32	2	1772416
Pubmed	A Method to Identify p62's UBA Domain Interacting Proteins.	NCOR1 RELN	7.41e-05	14	32	2	14702098
Pubmed	The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.	TAF1 TAF1L	8.55e-05	15	32	2	14580349
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	IFT172 DNAH17	1.54e-04	20	32	2	21689717
Pubmed	Parkinson Disease Overview	TAF1 SNCAIP	2.84e-04	27	32	2	20301402
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	DNHD1 HYOU1 PDIK1L DNAH17	3.33e-04	363	32	4	25036637
Pubmed	Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.	TAF1 TAF1L	3.75e-04	31	32	2	25838543
Pubmed	Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.	TAF1 TAF1L	7.23e-04	43	32	2	18722179
Pubmed	TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.	TAF1 TAF1L	8.28e-04	46	32	2	25209997
Cytoband	9q32	KIF12 C9orf43	4.99e-04	47	32	2	9q32
Cytoband	Ensembl 112 genes in cytogenetic band chr9q32	KIF12 C9orf43	5.65e-04	50	32	2	chr9q32
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RAPH1 PREX1 DOCK9	1.91e-03	206	22	3	682
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF12 C9orf43 PREX1 DNAH17	7.64e-06	177	32	4	14fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 RELN SNCAIP PKD1L3	1.14e-05	196	32	4	09a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 RELN SNCAIP PKD1L3	1.14e-05	196	32	4	e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	DNHD1 RAPH1 IFT172 DOCK9	1.21e-05	199	32	4	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 BNC2 RAPH1 ANGPTL7	1.24e-05	200	32	4	be46efc899d06c55ee297bee3126f69bcdb2048b
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 BNC2 RAPH1 ANGPTL7	1.24e-05	200	32	4	5ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCell	VE-CD4-CD8_1\|VE / Condition, Cell_class and T cell subcluster	DNHD1 C9orf43 PTPRH	9.33e-05	123	32	3	bc0f509716bb71d6e3fa343f4920ecb80eb62794
ToppCell	metastatic_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	C9orf43 SNCAIP INCENP	1.81e-04	154	32	3	423f58fc7dcef068458cbf7b4ee989e37227041e
ToppCell	COVID-19-kidney-Lymphatic_EC\|kidney / Disease (COVID-19 only), tissue and cell type	RELN SNCAIP DOCK9	2.30e-04	167	32	3	97d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell	normal-na-Lymphocytic_NK-natural_killer_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	BTBD9 HYOU1 CCNB3	2.47e-04	171	32	3	d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN ZMAT1 DOCK9	2.64e-04	175	32	3	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	Control-Neuronal_cells\|Control / group, cell type (main and fine annotations)	RELN SNCAIP DOCK9	2.69e-04	176	32	3	c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN SNCAIP DOCK9	2.69e-04	176	32	3	460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCell	metastatic_Brain-Endothelial_cells-Lymphatic_ECs\|Endothelial_cells / Location, Cell class and cell subclass	ADAMTS12 RELN QRICH2	2.69e-04	176	32	3	42541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCell	Control-Neuronal_cells-Neuronal_cells\|Control / group, cell type (main and fine annotations)	RELN SNCAIP DOCK9	2.69e-04	176	32	3	98c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF12 PREX1 DNAH17	2.69e-04	176	32	3	5e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell	COVID-19-Heart-Lymph_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RELN SNCAIP DOCK9	2.73e-04	177	32	3	326fde0734ef0d7272693966d346ca479b9d8147
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	2.73e-04	177	32	3	227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	2.73e-04	177	32	3	66ffa279147961080c104242a08b176e301d80e3
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	2.73e-04	177	32	3	0cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KIF12 BNC2 RELN	2.78e-04	178	32	3	544379f5a6145429762258d426b876bb36c112f5
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	RELN SNCAIP PKD1L3	2.78e-04	178	32	3	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RELN SNCAIP PKD1L3	2.78e-04	178	32	3	ad3de3e03a401dac64431a541899445262246347
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN HYOU1 MMADHC	2.78e-04	178	32	3	b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCell	metastatic_Brain-Endothelial_cells-Lymphatic_ECs\|metastatic_Brain / Location, Cell class and cell subclass	ADAMTS12 RELN QRICH2	2.82e-04	179	32	3	56fe381ffbaba3a4f2f587a3e367b0d11fbd4a2a
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN SNCAIP DOCK9	2.96e-04	182	32	3	d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS12 BNC2 SNCAIP	3.11e-04	185	32	3	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SNCAIP DOCK9	3.11e-04	185	32	3	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN SNCAIP DOCK9	3.11e-04	185	32	3	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	RELN SNCAIP DOCK9	3.11e-04	185	32	3	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	RELN SNCAIP DOCK9	3.11e-04	185	32	3	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SNCAIP DOCK9	3.11e-04	185	32	3	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	356C-Endothelial_cells-Endothelial-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	TAF1L QRICH2 DOCK9	3.16e-04	186	32	3	2e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell	356C-Endothelial_cells-Endothelial-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	TAF1L QRICH2 DOCK9	3.16e-04	186	32	3	c3449e54454009973818fc1101933c6f0168258c
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RELN SNCAIP PKD1L3	3.16e-04	186	32	3	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAPH1 PREX1 DOCK9	3.21e-04	187	32	3	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAPH1 PREX1 DOCK9	3.21e-04	187	32	3	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SNCAIP PREX1 DOCK9	3.21e-04	187	32	3	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	3.36e-04	190	32	3	876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	RELN SNCAIP PKD1L3	3.36e-04	190	32	3	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	3.36e-04	190	32	3	be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	3.36e-04	190	32	3	09a8855901c3c9332dbaab3e40166485b696d0f1
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN ANGPTL7 PREX1	3.52e-04	193	32	3	3ea6b103e35bbb276e95301999618558fa3e38b1
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 BNC2 ANGPTL7	3.52e-04	193	32	3	549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNCAIP PREX1 DOCK9	3.52e-04	193	32	3	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RELN PKD1L3 ABCA7	3.52e-04	193	32	3	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNCAIP PREX1 DOCK9	3.52e-04	193	32	3	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF12 NCOR1 HYOU1	3.57e-04	194	32	3	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF12 NCOR1 HYOU1	3.57e-04	194	32	3	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF12 NCOR1 RELN	3.62e-04	195	32	3	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SNCAIP DOCK9	3.62e-04	195	32	3	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF12 NCOR1 RELN	3.62e-04	195	32	3	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNCAIP PREX1 DOCK9	3.62e-04	195	32	3	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	facs-GAT-Fat-3m-Endothelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SNCAIP DOCK9	3.68e-04	196	32	3	b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 BNC2 SNCAIP	3.68e-04	196	32	3	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	3.68e-04	196	32	3	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	RELN BTBD9 DOCK9	3.68e-04	196	32	3	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	facs-GAT-Fat-3m-Endothelial-endothelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SNCAIP DOCK9	3.68e-04	196	32	3	ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCell	facs-GAT-Fat-3m-Endothelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SNCAIP DOCK9	3.68e-04	196	32	3	039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	3.68e-04	196	32	3	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNCAIP PREX1 DOCK9	3.68e-04	196	32	3	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN SNCAIP DOCK9	3.68e-04	196	32	3	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNCAIP PREX1 DOCK9	3.79e-04	198	32	3	07701c73137947ed4a27e225975329235bbb8734
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 BNC2 ANGPTL7	3.85e-04	199	32	3	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 SNCAIP ANGPTL7	3.90e-04	200	32	3	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 ABHD4 ANGPTL7	3.90e-04	200	32	3	29054cf55e88e1ac81a562d8dd9af9b7c749321d
Drug	Mfpa	TAF1 TAF1L	5.74e-06	3	32	2	CID003035615
Disease	osteoarthritis, knee, body mass index	BNC2 PKD1L3	8.54e-04	41	31	2	EFO_0004340, EFO_0004616
Disease	Carcinoma, Transitional Cell	NCOR1 APAF1	8.54e-04	41	31	2	C0007138
Disease	forced expiratory volume	NCOR1 BNC2 PREX1 PDIK1L DOCK9	1.29e-03	789	31	5	EFO_0004314
Disease	osteoarthritis	KIF12 RELN RAPH1	1.62e-03	222	31	3	MONDO_0005178
Disease	body fat percentage	BNC2 RELN HYOU1 APAF1	1.63e-03	488	31	4	EFO_0007800
Disease	pyroglutamine measurement	BNC2 RELN	1.70e-03	58	31	2	EFO_0005408
Disease	Major Depressive Disorder	RELN RAPH1 APAF1	2.09e-03	243	31	3	C1269683
Disease	squamous cell carcinoma	ADAMTS12 BNC2	2.26e-03	67	31	2	EFO_0000707
Disease	Unipolar Depression	RELN RAPH1 APAF1	2.51e-03	259	31	3	C0041696
Disease	hypothyroidism (biomarker_via_orthology)	NCOR1 RELN	3.21e-03	80	31	2	DOID:1459 (biomarker_via_orthology)
Disease	otosclerosis	RELN PREX1	3.29e-03	81	31	2	EFO_0004213
Disease	Acute Confusional Senile Dementia	RELN ABCA7	4.86e-03	99	31	2	C0546126
Disease	Presenile dementia	RELN ABCA7	4.86e-03	99	31	2	C0011265
Disease	Alzheimer's Disease, Focal Onset	RELN ABCA7	4.86e-03	99	31	2	C0750900
Disease	Alzheimer Disease, Early Onset	RELN ABCA7	4.86e-03	99	31	2	C0750901
Disease	Alzheimer Disease, Late Onset	RELN ABCA7	4.86e-03	99	31	2	C0494463
Disease	Familial Alzheimer Disease (FAD)	RELN ABCA7	4.96e-03	100	31	2	C0276496
Disease	Alzheimer's Disease	RELN ABCA7	5.06e-03	101	31	2	C0002395

Protein segments in the cluster

Peptide	Gene	Start	Entry
CILWDMETEEVEDIL	APAF1	401	O14727
DRWAIMSREEEIITL	BNC2	231	Q6ZN30
EDEFVTSIETWRETM	ABHD4	121	Q8TB40
VLVAEEVVWRAEMEE	DNHD1	1511	Q96M86
RWVETLVVADTKMIE	ADAMTS12	246	P58397
EELTLLRDVREVWEM	ABCA7	316	Q8IZY2
ITSDMRAILVDWLVE	CCNB3	1156	Q8WWL7
DWSLVETVSELQMER	RAPH1	311	Q70E73
EEVTMVTWEELEQAI	QRICH2	46	Q9H0J4
AEMLVELVWRIERSE	MRFAP1L1	111	Q96HT8
TVDLDTFLVVMRDWI	KASH5	91	Q8N6L0
ERDWVSVVMQVMELE	ANGPTL7	71	O43827
MTVWSEEVEIEREVL	MMADHC	186	Q9H3L0
LVWLEEIQEEAERMF	INCENP	31	Q9NQS7
WTQTRVLAEMLTEEE	KIF12	566	Q96FN5
EDVWAIDEIIMTSVL	RELN	851	P78509
EREEVRDWVLTVSMD	IFT172	1641	Q9UG01
EVEMTTLEKVINETW	HYOU1	851	Q9Y4L1
LAADSEVEMEEWITI	DOCK9	261	Q9BZ29
ELWDMVVVVNTSIED	DNAH17	1281	Q9UFH2
DVRNMVVLWIPEETE	C9orf43	131	Q8TAL5
IEVSMDELDWVRVID	BTBD9	351	Q96Q07
RWEVIDVVRTMSTEQ	TAF1L	1041	Q8IZX4
SRWEVIDVVRTMSTE	TAF1	1021	P21675
EPVETSRWTEEEMEV	NCOR1	621	O75376
IIWAMLERITFIDTE	PDIK1L	246	Q8N165
EDIEIMLWRNVSLET	PKD1L3	506	Q7Z443
EERTMLEDIWVTLSE	PREX1	1391	Q8TCU6
VRWMVSETEAIAELS	SNCAIP	401	Q9Y6H5
MEEEEIRTWSFPEEV	ZNF815P	1	A8K554
RVTLVGEEVMENWTV	PTPRH	946	Q9HD43
VEERTEEEMLWDESI	ZMAT1	621	Q5H9K5