Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aminoacyltransferase activity	TRIM49 TRAF6 SH3RF1 NEDD4L TRIM49C MIB2 HUWE1 TGM5 TGM4 PJA2 RNF214 MIB1 TRIM49B	9.00e-05	532	139	13	GO:0016755
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	TRIM49 TRAF6 SH3RF1 NEDD4L TRIM49C MIB2 HUWE1 PJA2 MIB1 TRIM49B	2.83e-04	372	139	10	GO:0061630
GeneOntologyMolecularFunction	group III metabotropic glutamate receptor activity	GRM4 GRM6	2.86e-04	4	139	2	GO:0001642
GeneOntologyMolecularFunction	zinc ion binding	TRIM49 MYBBP1A SETMAR TRAF6 TUT7 TRIM49C MIB2 APOBEC3B BHMT ZNF512B BMP1 MIB1 TRIM49B UTRN TARS1 SMAD3	4.80e-04	891	139	16	GO:0008270
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	TRIM49 TRAF6 SH3RF1 NEDD4L TRIM49C MIB2 HUWE1 PJA2 MIB1 TRIM49B	4.81e-04	398	139	10	GO:0061659
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	TRIM49 TRAF6 SH3RF1 NEDD4L TRIM49C MIB2 HUWE1 PJA2 RNF214 MIB1 TRIM49B	4.82e-04	473	139	11	GO:0004842
GeneOntologyMolecularFunction	phosphatidylinositol phospholipase C activity	PLCD3 GDPD5 PLCB4	7.63e-04	26	139	3	GO:0004435
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	TRIM49 TRAF6 SH3RF1 NEDD4L TRIM49C MIB2 HUWE1 PJA2 RNF214 MIB1 TRIM49B	9.25e-04	512	139	11	GO:0019787
GeneOntologyMolecularFunction	acyltransferase activity	TRIM49 AANAT TRAF6 SH3RF1 NEDD4L TRIM49C MIB2 HUWE1 TGM5 TGM4 PJA2 RNF214 MIB1 TRIM49B	1.04e-03	775	139	14	GO:0016746
GeneOntologyMolecularFunction	phospholipase C activity	PLCD3 GDPD5 PLCB4	1.06e-03	29	139	3	GO:0004629
GeneOntologyCellularComponent	laminin-11 complex	LAMA5 LAMB2	1.31e-04	3	139	2	GO:0043260
GeneOntologyCellularComponent	centriolar satellite	FLII PJA2 TBC1D31 MIB1 WDR62 PCNT	2.16e-04	128	139	6	GO:0034451
Domain	ConA-like_dom	TRIM49 TRIM49C LAMA5 MDGA2 PTPRU ITGB4 LMAN1 TRIM49B AGRN	3.28e-05	219	136	9	IPR013320
Domain	DUF4659	CCDC185 CCDC177	5.26e-05	2	136	2	IPR029090
Domain	DUF4659	CCDC185 CCDC177	5.26e-05	2	136	2	PF15558
Domain	SPEC	SESTD1 SYNE1 EVPL UTRN	8.26e-05	32	136	4	SM00150
Domain	Spectrin/alpha-actinin	SESTD1 SYNE1 EVPL UTRN	8.26e-05	32	136	4	IPR018159
Domain	PH	CDC42BPA PLEKHG4 KIF1B EXOC8 PLCD3 ARHGEF40 PLEKHG6 ARHGAP12 OSBPL7	2.03e-04	278	136	9	SM00233
Domain	PH_DOMAIN	CDC42BPA PLEKHG4 KIF1B EXOC8 PLCD3 ARHGEF40 PLEKHG6 ARHGAP12 OSBPL7	2.09e-04	279	136	9	PS50003
Domain	PH_domain	CDC42BPA PLEKHG4 KIF1B EXOC8 PLCD3 ARHGEF40 PLEKHG6 ARHGAP12 OSBPL7	2.14e-04	280	136	9	IPR001849
Domain	ZF_ZZ_2	MIB2 MIB1 UTRN	2.84e-04	18	136	3	PS50135
Domain	ZF_ZZ_1	MIB2 MIB1 UTRN	2.84e-04	18	136	3	PS01357
Domain	ZZ	MIB2 MIB1 UTRN	2.84e-04	18	136	3	PF00569
Domain	ZF_RING_1	TRIM49 TRAF6 SH3RF1 TRIM49C MIB2 PJA2 RNF214 MIB1 TRIM49B	2.85e-04	291	136	9	PS00518
Domain	Kinesin-like_KIF1-typ	KIF1B KIF13A	3.13e-04	4	136	2	IPR022140
Domain	KIF1B	KIF1B KIF13A	3.13e-04	4	136	2	PF12423
Domain	Mib_Herc2	MIB2 MIB1	3.13e-04	4	136	2	IPR010606
Domain	MIB_HERC2	MIB2 MIB1	3.13e-04	4	136	2	PS51416
Domain	MIB_HERC2	MIB2 MIB1	3.13e-04	4	136	2	PF06701
Domain	Znf_ZZ	MIB2 MIB1 UTRN	3.36e-04	19	136	3	IPR000433
Domain	ZnF_ZZ	MIB2 MIB1 UTRN	3.36e-04	19	136	3	SM00291
Domain	ZF_RING_2	TRIM49 TRAF6 SH3RF1 TRIM49C MIB2 PJA2 RNF214 MIB1 TRIM49B	3.39e-04	298	136	9	PS50089
Domain	RING	TRIM49 TRAF6 SH3RF1 TRIM49C MIB2 PJA2 RNF214 MIB1 TRIM49B	4.01e-04	305	136	9	SM00184
Domain	SMAD_FHA_domain	KIF1B KIF16B KIF13A SMAD3	5.55e-04	52	136	4	IPR008984
Domain	-	CDC42BPA PLEKHG4 KIF1B EXOC8 PLCD3 ARHGEF40 PLEKHG6 ARHGAP12 OSBPL7 PLCB4	5.91e-04	391	136	10	2.30.29.30
Domain	Znf_RING	TRIM49 TRAF6 SH3RF1 TRIM49C MIB2 PJA2 RNF214 MIB1 TRIM49B	6.48e-04	326	136	9	IPR001841
Domain	-	PLCD3 GDPD5 PLCB4	7.72e-04	25	136	3	3.20.20.190
Domain	PLC-like_Pdiesterase_TIM-brl	PLCD3 GDPD5 PLCB4	7.72e-04	25	136	3	IPR017946
Domain	Kinesin_assoc	KIF1B KIF13A	7.75e-04	6	136	2	PF16183
Domain	Kinesin-like	KIF1B KIF13A	7.75e-04	6	136	2	IPR022164
Domain	Kinesin_assoc	KIF1B KIF13A	7.75e-04	6	136	2	IPR032405
Domain	DUF3694	KIF1B KIF13A	7.75e-04	6	136	2	PF12473
Domain	FHA	KIF1B KIF16B KIF13A	1.08e-03	28	136	3	SM00240
Domain	PH_dom-like	CDC42BPA PLEKHG4 KIF1B EXOC8 PLCD3 ARHGEF40 PLEKHG6 ARHGAP12 OSBPL7 PLCB4	1.13e-03	426	136	10	IPR011993
Domain	Spectrin_repeat	SYNE1 EVPL UTRN	1.20e-03	29	136	3	IPR002017
Domain	EGF_LAM_2	LAMA5 LAMB2 AGRN	1.33e-03	30	136	3	PS50027
Domain	EGF_LAM_1	LAMA5 LAMB2 AGRN	1.33e-03	30	136	3	PS01248
Domain	GPCR_3_mtglu_rcpt	GRM4 GRM6	1.43e-03	8	136	2	IPR000162
Domain	FHA_DOMAIN	KIF1B KIF16B KIF13A	1.46e-03	31	136	3	PS50006
Domain	FHA	KIF1B KIF16B KIF13A	1.46e-03	31	136	3	PF00498
Domain	Transglut_N	TGM5 TGM4	1.83e-03	9	136	2	PF00868
Domain	TRANSGLUTAMINASES	TGM5 TGM4	1.83e-03	9	136	2	PS00547
Domain	-	TGM5 TGM4	1.83e-03	9	136	2	3.90.260.10
Domain	Gln_gamma-glutamylTfrase_euk	TGM5 TGM4	1.83e-03	9	136	2	IPR023608
Domain	Transglutaminase_AS	TGM5 TGM4	1.83e-03	9	136	2	IPR013808
Domain	Transglutaminase_N	TGM5 TGM4	1.83e-03	9	136	2	IPR001102
Domain	Transglut_C	TGM5 TGM4	1.83e-03	9	136	2	PF00927
Domain	EGF_Lam	LAMA5 LAMB2 AGRN	2.08e-03	35	136	3	SM00180
Domain	Laminin_EGF	LAMA5 LAMB2 AGRN	2.08e-03	35	136	3	PF00053
Domain	-	KIF1B KIF16B KIF13A	2.26e-03	36	136	3	2.60.200.20
Domain	FHA_dom	KIF1B KIF16B KIF13A	2.26e-03	36	136	3	IPR000253
Domain	Leu-rich_rpt_4	PODNL1 FLII	2.28e-03	10	136	2	IPR025875
Domain	Transglutaminase_C	TGM5 TGM4	2.28e-03	10	136	2	IPR008958
Domain	LRR_4	PODNL1 FLII	2.28e-03	10	136	2	PF12799
Domain	Laminin_EGF	LAMA5 LAMB2 AGRN	2.64e-03	38	136	3	IPR002049
Domain	Transglutaminase-like	TGM5 TGM4	2.77e-03	11	136	2	IPR002931
Domain	TGc	TGM5 TGM4	2.77e-03	11	136	2	SM00460
Domain	Transglut_core	TGM5 TGM4	2.77e-03	11	136	2	PF01841
Domain	Kinesin_motor_CS	KIF1B KIF16B KIF13A	3.29e-03	41	136	3	IPR019821
Domain	Kinesin-like_fam	KIF1B KIF16B KIF13A	3.77e-03	43	136	3	IPR027640
Domain	NCD3G	GRM4 GRM6	3.90e-03	13	136	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM4 GRM6	3.90e-03	13	136	2	IPR011500
Domain	-	KIF1B KIF16B KIF13A	4.02e-03	44	136	3	3.40.850.10
Domain	Kinesin	KIF1B KIF16B KIF13A	4.02e-03	44	136	3	PF00225
Domain	KISc	KIF1B KIF16B KIF13A	4.02e-03	44	136	3	SM00129
Domain	KINESIN_MOTOR_1	KIF1B KIF16B KIF13A	4.02e-03	44	136	3	PS00411
Domain	Kinesin_motor_dom	KIF1B KIF16B KIF13A	4.02e-03	44	136	3	IPR001752
Domain	KINESIN_MOTOR_2	KIF1B KIF16B KIF13A	4.02e-03	44	136	3	PS50067
Domain	GPCR_3_CS	GRM4 GRM6	4.52e-03	14	136	2	IPR017979
Domain	WW	NEDD4L ARHGAP12 UTRN	4.85e-03	47	136	3	PF00397
Domain	WW	NEDD4L ARHGAP12 UTRN	5.14e-03	48	136	3	SM00456
Domain	EF-hand_like	PLCD3 PLCB4	5.19e-03	15	136	2	PF09279
Domain	PI-PLC-Y	PLCD3 PLCB4	5.19e-03	15	136	2	PF00387
Domain	PLCYc	PLCD3 PLCB4	5.19e-03	15	136	2	SM00149
Domain	PLipase_C_Pinositol-sp_Y	PLCD3 PLCB4	5.19e-03	15	136	2	IPR001711
Domain	PIPLC_Y_DOMAIN	PLCD3 PLCB4	5.19e-03	15	136	2	PS50008
Domain	PI-PLC_fam	PLCD3 PLCB4	5.19e-03	15	136	2	IPR001192
Domain	PLC_EF-hand-like	PLCD3 PLCB4	5.19e-03	15	136	2	IPR015359
Domain	-	TRIM49 TRAF6 SH3RF1 TRIM49C MIB2 PJA2 RNF214 MIB1 TRIM49B	5.65e-03	449	136	9	3.30.40.10
Domain	MAM_1	MDGA2 PTPRU	5.91e-03	16	136	2	PS00740
Domain	Laminin_N	LAMA5 LAMB2	5.91e-03	16	136	2	IPR008211
Domain	LamNT	LAMA5 LAMB2	5.91e-03	16	136	2	SM00136
Domain	LAMININ_NTER	LAMA5 LAMB2	5.91e-03	16	136	2	PS51117
Domain	Laminin_N	LAMA5 LAMB2	5.91e-03	16	136	2	PF00055
Domain	WW_DOMAIN_1	NEDD4L ARHGAP12 UTRN	6.09e-03	51	136	3	PS01159
Domain	WW_DOMAIN_2	NEDD4L ARHGAP12 UTRN	6.09e-03	51	136	3	PS50020
Domain	WW_dom	NEDD4L ARHGAP12 UTRN	6.43e-03	52	136	3	IPR001202
Domain	Znf_RING/FYVE/PHD	TRIM49 TRAF6 SH3RF1 TRIM49C MIB2 PJA2 RNF214 MIB1 TRIM49B	6.49e-03	459	136	9	IPR013083
Domain	MAM	MDGA2 PTPRU	6.66e-03	17	136	2	SM00137
Domain	PH	CDC42BPA PLEKHG4 KIF1B EXOC8 ARHGAP12 OSBPL7	6.67e-03	229	136	6	PF00169
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	LAMA5 LAMB2 SYNPO ITGB4 CTNNB1 UTRN AGRN	9.64e-07	72	104	7	M39403
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	LAMA5 LAMB2 SYNPO ITGB4 CTNNB1 UTRN AGRN	1.06e-06	73	104	7	MM15906
Pathway	PID_INTEGRIN4_PATHWAY	LAMA5 LAMB2 ITGB4	6.17e-05	11	104	3	M158
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	HNRNPDL FLII DCAF8 RBM10 HJURP PER1 PFAS HUWE1 CTNNB1 WDR62	4.43e-08	232	142	10	25515538
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLII CDC42BPA SH3RF1 POLRMT PER1 LAMA5 LAMB2 PFAS TMCO6 MIB2 HUWE1 ITGB4 PLCD3 GDPD5 ZNF263 ARHGEF40 AGRN PCNT	6.49e-07	1105	142	18	35748872
Pubmed	Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.	LAMA5 LAMB2 ITGB4	6.62e-07	5	142	3	16581764
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MYBBP1A TMEM186 CDC42BPA DCAF8 SYNE1 KIF16B MYO18A POLRMT PFAS FASTKD2 ZNF512B PJA2 TBC1D31 LMAN1 BUB1B MIB1 TTC13 CTNNB1 TARS1 WDR62 PCNT	7.18e-07	1487	142	21	33957083
Pubmed	Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins.	LAMA5 LAMB2 ITGB4	1.32e-06	6	142	3	10671376
Pubmed	The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin.	LAMA5 ITGB4 RAPGEF3	2.30e-06	7	142	3	15302884
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	HNRNPDL FLII MYBBP1A PLEKHG4 TUT7 POLRMT PFAS FASTKD2 VPS16 HUWE1 DUS3L PLCD3 ARHGEF40 AP2M1 EIF2B5 MIB1 UTRN AGRN TARS1	2.78e-06	1353	142	19	29467282
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	HNRNPDL FLII MYBBP1A SYNE1 TUT7 KIF16B POLRMT UQCC2 FASTKD2 HUWE1 SLC30A6 ZNF512B MTRF1 VPS13D LMAN1 ARHGAP12 MIB1 TTC13 WDR62 PCNT	3.11e-06	1496	142	20	32877691
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	TRAF6 MIB2 HUWE1 MIB1	5.05e-06	28	142	4	35474067
Pubmed	A human MAP kinase interactome.	CDC42BPA SH3RF1 NEDD4L SYNE1 MYO18A LAMB2 EVPL SYNPO NEB ITGB4 PROM1	5.46e-06	486	142	11	20936779
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	CDC42BPA PLEKHG4 UQCC2 HUWE1 DUS3L PJA2 ARHGEF40 AP2M1 PLEKHG6 ARHGAP12 MIB1 ELANE LSM11 CTNNB1 UTRN	5.57e-06	916	142	15	32203420
Pubmed	Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.	LAMA5 LAMB2 SYNPO	1.07e-05	11	142	3	11435469
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SCAF8 TUT7 POLRMT CC2D1B PFAS MIB2 EXOC8 PLCD3 ARHGEF40 EIF2B5 BUB1B AGRN	1.57e-05	650	142	12	38777146
Pubmed	Neutrophil elastase cleaves laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophils.	LAMA5 ELANE	1.66e-05	2	142	2	18178964
Pubmed	Beta-Catenin and SMAD3 Are Associated with Skeletal Muscle Aging in the Taurine Transpoeter Knockout Mouse.	CTNNB1 SMAD3	1.66e-05	2	142	2	28849477
Pubmed	Targeted disruption of Mib2 causes exencephaly with a variable penetrance.	MIB2 MIB1	1.66e-05	2	142	2	17987667
Pubmed	NEDD4L mediates ITGB4 ubiquitination and degradation to suppress esophageal carcinoma progression.	NEDD4L ITGB4	1.66e-05	2	142	2	38831335
Pubmed	Expression of synaptopodin and GLEPP1 as markers of steroid responsiveness in primary focal segmental glomerulosclerosis.	SYNPO PTPRU	1.66e-05	2	142	2	16564554
Pubmed	The junctional epithelium originates from the odontogenic epithelium of an erupted tooth.	LAMA5 ITGB4	1.66e-05	2	142	2	24785116
Pubmed	ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L.	NEDD4L CTNNB1	1.66e-05	2	142	2	34330894
Pubmed	Novel genetic variants in KIF16B and NEDD4L in the endosome-related genes are associated with nonsmall cell lung cancer survival.	NEDD4L KIF16B	1.66e-05	2	142	2	31618441
Pubmed	A novel protein-tyrosine phosphatase related to the homotypically adhering kappa and mu receptors.	PTPRU CTNNB1	1.66e-05	2	142	2	9054423
Pubmed	Bcl-3 promotes Wnt signaling by maintaining the acetylation of β-catenin at lysine 49 in colorectal cancer.	BCL3 CTNNB1	1.66e-05	2	142	2	32355204
Pubmed	Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility.	PTPRU CTNNB1	1.66e-05	2	142	2	24876153
Pubmed	Physical and functional interaction between receptor-like protein tyrosine phosphatase PCP-2 and beta-catenin.	PTPRU CTNNB1	1.66e-05	2	142	2	12501215
Pubmed	hCLP46 increases Smad3 protein stability via inhibiting its ubiquitin-proteasomal degradation.	POGLUT1 SMAD3	1.66e-05	2	142	2	26058784
Pubmed	BCL-3 and β-catenin signaling and tumor staging in colorectal cancer.	BCL3 CTNNB1	1.66e-05	2	142	2	33040819
Pubmed	Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.	LAMA5 LAMB2 AGRN	1.85e-05	13	142	3	12682087
Pubmed	Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.	LAMA5 LAMB2 ITGB4	1.85e-05	13	142	3	9670011
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLII MYBBP1A CDC42BPA TUT7 MYO18A ITGB4 ARHGEF40	2.06e-05	202	142	7	33005030
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM49 TRIM49C TRIM49B	2.92e-05	15	142	3	19703589
Pubmed	Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.	LAMA5 ITGB4 PROM1	3.59e-05	16	142	3	21067603
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	PODNL1 SYNE1 NEB BMP1 NEK5 AGRN	3.96e-05	152	142	6	34299191
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	FLII SESTD1 MYBBP1A NEDD4L SYNE1 CALCOCO1 SYNPO HUWE1 GRM4 CCDC177 ZNF263 CTNNB1 AGRN PCNT	4.28e-05	963	142	14	28671696
Pubmed	Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.	PLEKHG4 PPP2R2B FGF14	4.35e-05	17	142	3	15148151
Pubmed	CD133 expression correlates with membrane beta-catenin and E-cadherin loss from human hair follicle placodes during morphogenesis.	PROM1 CTNNB1	4.95e-05	3	142	2	25010141
Pubmed	A role for PAK1 mediated phosphorylation of β-catenin Ser552 in the regulation of insulin secretion.	RAPGEF3 CTNNB1	4.95e-05	3	142	2	33605402
Pubmed	PFKFB3 promotes endometriosis cell proliferation via enhancing the protein stability of β-catenin.	PFKFB3 CTNNB1	4.95e-05	3	142	2	37820851
Pubmed	Detection of β-catenin, gastrokine-2 and embryonic stem cell expressed ras in gastric cancers.	ERAS CTNNB1	4.95e-05	3	142	2	21151392
Pubmed	BCL3 regulates RANKL-induced osteoclastogenesis by interacting with TRAF6 in bone marrow-derived macrophages.	TRAF6 BCL3	4.95e-05	3	142	2	29933112
Pubmed	Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).	CTNNB1 SMAD3	4.95e-05	3	142	2	22241478
Pubmed	E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.	HUWE1 CTNNB1	4.95e-05	3	142	2	28137882
Pubmed	Mind bomb-2 is an E3 ligase for Notch ligand.	MIB2 MIB1	4.95e-05	3	142	2	15824097
Pubmed	Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier.	LAMA5 LAMB2	4.95e-05	3	142	2	16886065
Pubmed	Smad3 prevents beta-catenin degradation and facilitates beta-catenin nuclear translocation in chondrocytes.	CTNNB1 SMAD3	4.95e-05	3	142	2	20097766
Pubmed	Hsa_circ_0088036 promotes nonsmall cell lung cancer progression by regulating miR-1343-3p/Bcl-3 axis through TGFβ/Smad3/EMT signaling.	BCL3 SMAD3	4.95e-05	3	142	2	37132942
Pubmed	Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion.	PTPRU CTNNB1	4.95e-05	3	142	2	16574648
Pubmed	The transcription factor Lef1 switches partners from β-catenin to Smad3 during muscle stem cell quiescence.	CTNNB1 SMAD3	4.95e-05	3	142	2	30042129
Pubmed	Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium.	NEDD4L AP2M1	4.95e-05	3	142	2	23529131
Pubmed	The role of laminins in the organization and function of neuromuscular junctions.	LAMA5 LAMB2	4.95e-05	3	142	2	27614294
Pubmed	Kruppel-like factor 13 inhibits cell proliferation of gastric cancer by inducing autophagic degradation of β-catenin.	TRAF6 CTNNB1	4.95e-05	3	142	2	36336731
Pubmed	Wnt/β-catenin Signaling Inhibitors suppress the Tumor-initiating properties of a CD44+CD133+ subpopulation of Caco-2 cells.	PROM1 CTNNB1	4.95e-05	3	142	2	33994850
Pubmed	A Flow Cytometry-Based Approach for the Isolation and Characterization of Neural Stem Cell Primary Cilia.	PROM1 CTNNB1	4.95e-05	3	142	2	30692915
Pubmed	HNE Induces the Hyperexpression of MUC5AC in Chronic Rhinosinusitis With Nasal Polyps by Activating the TRAF6/Autophagy Regulatory Axis.	TRAF6 ELANE	4.95e-05	3	142	2	35915986
Pubmed	Association of β-catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF-β1.	CTNNB1 SMAD3	4.95e-05	3	142	2	23203799
Pubmed	Bcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasis.	BCL3 SMAD3	4.95e-05	3	142	2	27906182
Pubmed	Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.	LAMA5 ITGB4	4.95e-05	3	142	2	15316072
Pubmed	Regulation of CD133 by HDAC6 promotes β-catenin signaling to suppress cancer cell differentiation.	PROM1 CTNNB1	4.95e-05	3	142	2	23084749
Pubmed	A Wnt- and beta -catenin-dependent pathway for mammalian cardiac myogenesis.	WNT8A CTNNB1	4.95e-05	3	142	2	12719544
Pubmed	Muscle and neural isoforms of agrin increase utrophin expression in cultured myotubes via a transcriptional regulatory mechanism.	UTRN AGRN	4.95e-05	3	142	2	9422725
Pubmed	Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes.	CTNNB1 SMAD3	4.95e-05	3	142	2	16690606
Pubmed	Laminin-11.	LAMA5 LAMB2	4.95e-05	3	142	2	10481268
Pubmed	Polarized cell migration induces cancer type-specific CD133/integrin/Src/Akt/GSK3β/β-catenin signaling required for maintenance of cancer stem cell properties.	PROM1 CTNNB1	4.95e-05	3	142	2	26515729
Pubmed	Expression of laminin alpha 1, alpha 5 and beta 2 chains during embryogenesis of the kidney and vasculature.	LAMA5 LAMB2	4.95e-05	3	142	2	9049978
Pubmed	Regulation of RANKL-induced osteoclastogenesis by TGF-β through molecular interaction between Smad3 and Traf6.	TRAF6 SMAD3	4.95e-05	3	142	2	21305609
Pubmed	Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination.	PROM1 CTNNB1 PCNT	5.20e-05	18	142	3	18469343
Pubmed	Defective neuromuscular synaptogenesis in agrin-deficient mutant mice.	LAMB2 UTRN AGRN	5.20e-05	18	142	3	8653788
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDC42BPA CARMIL2 SH3RF1 NEDD4L KIF1B HJURP PJA2 VPS13D BUB1B GAN KIF13A UTRN WDR62	5.55e-05	861	142	13	36931259
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	HNRNPDL FLII MYBBP1A TUT7 MYO18A POLRMT EVPL SYNPO ITGB4 APOBEC3B AP2M1 PPP1R18 GAN SMARCD2 CTNNB1 TARS1	5.84e-05	1257	142	16	36526897
Pubmed	Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development.	ITGB4 PPP2R2B CTNNB1	6.15e-05	19	142	3	32582689
Pubmed	Identification of a genomic reservoir for new TRIM genes in primate genomes.	TRIM49 TRIM49C TRIM49B	6.15e-05	19	142	3	22144910
Pubmed	MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex.	PROM1 CTNNB1 PCNT	6.15e-05	19	142	3	19666823
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	FLII CALCOCO1 MYO18A SYNPO MIB2 VPS16 ATP9A CCDC177 CTNNB1	7.29e-05	430	142	9	32581705
Pubmed	Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.	HNRNPDL PER1 SMAD3	9.69e-05	22	142	3	18095154
Pubmed	The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.	SESTD1 CTNNB1	9.88e-05	4	142	2	20164195
Pubmed	Interleukin-6 signaling drives fibrosis in unresolved inflammation.	IL6R SMAD3	9.88e-05	4	142	2	24412616
Pubmed	Integrin alpha6beta4-erbB2 complex inhibits haptotaxis by up-regulating E-cadherin cell-cell junctions in keratinocytes.	LAMA5 ITGB4	9.88e-05	4	142	2	15579904
Pubmed	CNS Neurons Deposit Laminin α5 to Stabilize Synapses.	LAMA5 LAMB2	9.88e-05	4	142	2	29091766
Pubmed	Distribution of group-III metabotropic glutamate receptors in the retina.	GRM4 GRM6	9.88e-05	4	142	2	17311335
Pubmed	GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation.	GDPD5 CTNNB1	9.88e-05	4	142	2	32375055
Pubmed	Expression of the potential cancer stem cell markers, CD133, CD44, ALDH1, and β-catenin, in primary lung adenocarcinoma--their prognostic significance.	PROM1 CTNNB1	9.88e-05	4	142	2	23252868
Pubmed	Role of the N-terminal activation domain of the coiled-coil coactivator in mediating transcriptional activation by beta-catenin.	CALCOCO1 CTNNB1	9.88e-05	4	142	2	16931570
Pubmed	Regulation and Function of Laminin A5 during Mouse and Human Decidualization.	LAMA5 LAMB2	9.88e-05	4	142	2	35008625
Pubmed	A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.	CDC42BPA MYO18A	9.88e-05	4	142	2	18854160
Pubmed	Differentiation- and stress-dependent nuclear cytoplasmic redistribution of myopodin, a novel actin-bundling protein.	SYNJ2BP SYNPO	9.88e-05	4	142	2	11673475
Pubmed	Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing.	CTNNB1 SMAD3	9.88e-05	4	142	2	16581977
Pubmed	An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.	LAMA5 AGRN	9.88e-05	4	142	2	11565031
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	RCE1 NEDD4L TUT7 B3GALNT2 LAMA5 LAMB2 ATP9A ITGB4 BMP1 POGLUT1 LMAN1 TTC13 CTNNB1 AGRN WDR62	1.24e-04	1201	142	15	35696571
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	EVPL ITGB4 PPP1R18 UTRN PCNT	1.28e-04	118	142	5	30979931
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	PODNL1 DCAF8 SH3RF1 B3GALNT2 LAMB2 PFAS SYNPO ARHGAP12 EIF2B5 MIB1 SMAD3	1.30e-04	689	142	11	36543142
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	FLII SESTD1 HUWE1 PKD1L2 ZNF512B USP6 AP2M1	1.34e-04	272	142	7	18187620
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	FLII MYBBP1A CDC42BPA RBM10 MYO18A POLRMT CTNNB1	1.40e-04	274	142	7	34244482
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIF1B KIF16B KIF13A	1.43e-04	25	142	3	9275178
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	HNRNPDL SESTD1 MYBBP1A TUT7 HJURP HUWE1 DUS3L ITGB4 TGM4 TBC1D31 KIF13A UTRN AGRN PCNT	1.49e-04	1084	142	14	11544199
Pubmed	The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.	LAMB2 AGRN	1.64e-04	5	142	2	7670489
Pubmed	Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells.	RAPGEF3 CTNNB1	1.64e-04	5	142	2	20032304
Pubmed	Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation.	PROM1 CTNNB1	1.64e-04	5	142	2	26288357
Pubmed	A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.	CTNNB1 PCNT	1.64e-04	5	142	2	19774080
Pubmed	TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer.	TRAF6 CTNNB1	1.64e-04	5	142	2	31262711
Pubmed	Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4.	LAMB2 UTRN	1.64e-04	5	142	2	11369940
Interaction	PI15 interactions	LAMA5 LAMB2 MIB2 PTPRU BMP1 POGLUT1 AGRN	1.71e-06	83	139	7	int:PI15
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	MIB2 MIB1 UTRN	8.05e-05	18	86	3	91
GeneFamily	Ring finger proteins	TRIM49 TRAF6 SH3RF1 TRIM49C PJA2 RNF214 TRIM49B	3.37e-04	275	86	7	58
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM4 GRM6	6.15e-04	8	86	2	281
GeneFamily	Transglutaminases	TGM5 TGM4	7.88e-04	9	86	2	773
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF1B KIF16B KIF13A	1.36e-03	46	86	3	622
GeneFamily	Laminin subunits	LAMA5 LAMB2	1.43e-03	12	86	2	626
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG4 KIF1B PLEKHG6 ARHGAP12 OSBPL7	3.02e-03	206	86	5	682
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCD3 PLCB4	3.63e-03	19	86	2	832
GeneFamily	Ankyrin repeat domain containing	MIB2 BCL3 ANKRD22 MIB1 TRPV6	5.96e-03	242	86	5	403
ToppCell	distal-3-Hematologic-Platelet/Megakaryocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 NWD1 ERICH3 CLXN ELL3 PROM1 NEK5 CXorf58 FGF14	1.70e-08	200	142	9	f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	PRLHR KIF1B MYO18A ETNPPL ATP9A VPS13D DISP3 GAN	5.04e-08	161	142	8	347edb0de10850b7d16c40945751033289289c9b
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	LAMA5 LAMB2 EVPL ITGB4 PLCD3 OSBPL7 TRPV6 AGRN	8.41e-08	172	142	8	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 ERICH3 CLXN NEDD4L SYNE1 NEK5 FGF14 PLCB4	2.20e-07	195	142	8	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 ERICH3 CLXN NEDD4L SYNE1 NEK5 FGF14 PLCB4	2.20e-07	195	142	8	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SETMAR PCDHGC4 CALHM2 MTRF1 ARHGEF40 RAPGEF3 GPR153	1.16e-06	168	142	7	a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 HJURP APOBEC3B FFAR4 GPR153 BUB1B WDR62	1.41e-06	173	142	7	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 HJURP APOBEC3B FFAR4 GPR153 BUB1B WDR62	1.41e-06	173	142	7	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 EVPL MDGA2 ATP9A ITGB4 PLCB4 UTRN	1.77e-06	179	142	7	a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	1.98e-06	182	142	7	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	Ciliated_cells-B-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.21e-06	185	142	7	4fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCell	Ciliated_cells-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.29e-06	186	142	7	f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell	Ciliated_cells-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.37e-06	187	142	7	bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell	droplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA LAMA5 LAMB2 ITGB4 PLCB4 UTRN AGRN	2.46e-06	188	142	7	405efea75233ecf70f7d19b630230798d817b7f2
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.55e-06	189	142	7	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.55e-06	189	142	7	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	Ciliated_cells-B\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.64e-06	190	142	7	7031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.64e-06	190	142	7	a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCell	Epithelial_cells-Ciliated_cells-B\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.64e-06	190	142	7	426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.73e-06	191	142	7	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.73e-06	191	142	7	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	2.73e-06	191	142	7	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH3 NWD1 ERICH3 CLXN SYNE1 NEK5 FGF14	2.92e-06	193	142	7	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	SYNPO ITGB4 CALHM2 PLCD3 BMP1 PPP1R18 SMAD3	3.13e-06	195	142	7	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 ERICH3 SH3RF1 NEDD4L SYNE1 ATP9A PLCB4	3.24e-06	196	142	7	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 ERICH3 SH3RF1 NEDD4L SYNE1 ATP9A PLCB4	3.24e-06	196	142	7	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN SYNE1 PROM1 NEK5	3.35e-06	197	142	7	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN SYNE1 PROM1 NEK5	3.35e-06	197	142	7	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN SYNE1 PROM1 NEK5	3.35e-06	197	142	7	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN SYNE1 PROM1 NEK5	3.35e-06	197	142	7	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(II)\|lymph-node_spleen / Manually curated celltypes from each tissue	NEDD4L MYO18A NEB QRICH2 ZNF512B ELANE	9.44e-06	152	142	6	4f690aed23338687bdefc47e8a2f3d1fdb2b6447
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	APOBEC3B ZNF512B PPP2R2B TBC1D31 BUB1B OSBPL7	1.22e-05	159	142	6	2233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	SYNE1 MYO18A ATP9A VPS13D ARHGAP12 KIF13A	2.24e-05	177	142	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 ERICH3 CLXN BHMT PROM1 NEK5	2.31e-05	178	142	6	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMB2 SYNPO ITGB4 BMP1 PROM1 UTRN	2.54e-05	181	142	6	136b0c60680068838d184d32aa99d7bea8718dbc
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA5 EVPL MDGA2 ATP9A ITGB4 PLCB4	2.78e-05	184	142	6	f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA5 EVPL MDGA2 ATP9A ITGB4 PLCB4	2.78e-05	184	142	6	8bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCell	Ciliated_cells-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	2.78e-05	184	142	6	07c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	2.78e-05	184	142	6	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	2.87e-05	185	142	6	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	2.87e-05	185	142	6	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	2.87e-05	185	142	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	COPD-Epithelial-Ciliated\|COPD / Disease state, Lineage and Cell class	DNAH3 ERICH3 CLXN PROM1 NEK5 FGF14	3.05e-05	187	142	6	f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell	Ciliated_cells-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	3.05e-05	187	142	6	6fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	3.14e-05	188	142	6	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	Ciliated_cells-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	3.14e-05	188	142	6	606907c865bd2f11bb6474932716550f7723d858
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	3.14e-05	188	142	6	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	3.23e-05	189	142	6	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	CDC42BPA NEDD4L SYNE1 PFKFB3 FGF14 UTRN	3.23e-05	189	142	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	3.23e-05	189	142	6	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.23e-05	189	142	6	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	3.23e-05	189	142	6	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	Epithelial_cells-Ciliated_cells-A\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	3.33e-05	190	142	6	549d813a8f23b175875e53347928941f143e236c
ToppCell	Ciliated_cells-A\|World / lung cells shred on cell class, cell subclass, sample id	NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	3.33e-05	190	142	6	cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH3 NWD1 CLXN PROM1 NEK5 FGF14	3.43e-05	191	142	6	2a8e6d560907e71e9f6e190ca0667da804e25641
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 NWD1 CLXN PROM1 NEK5 FGF14	3.43e-05	191	142	6	46c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell	Mild_COVID-19-Epithelial-Ciliated\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DNAH3 NWD1 CLXN PROM1 NEK5 FGF14	3.43e-05	191	142	6	995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 NWD1 CLXN PROM1 NEK5 FGF14	3.43e-05	191	142	6	a37f20172b85566b9039254a89680e37fd503fd5
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH3 NWD1 CLXN PROM1 NEK5 FGF14	3.43e-05	191	142	6	2d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH3 ERICH3 CLXN SYNE1 PROM1 NEK5	3.53e-05	192	142	6	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH3 ERICH3 CLXN PROM1 NEK5 FGF14	3.53e-05	192	142	6	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.64e-05	193	142	6	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	3.64e-05	193	142	6	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH3 ERICH3 CLXN SYNE1 PROM1 NEK5	3.64e-05	193	142	6	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.74e-05	194	142	6	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical\|TCGA-Thryoid / Sample_Type by Project: Shred V9	FLII SYNPO ITGB4 PLCD3 BMP1 AGRN	3.74e-05	194	142	6	b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.85e-05	195	142	6	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DNAH3 ERICH3 CLXN NEK5 FGF14 PLCB4	3.85e-05	195	142	6	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	distal-Epithelial-Proximal_Ciliated\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 NWD1 ERICH3 CLXN PROM1 PCDHB1	3.85e-05	195	142	6	abe7998421dc59bdae35c0c2251c4a1ebef5e021
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.85e-05	195	142	6	581b04220587e1d5198b1abd6965965ace7803e7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.85e-05	195	142	6	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.85e-05	195	142	6	79dc031258579ea328181dda33710dd897f1064a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.85e-05	195	142	6	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.85e-05	195	142	6	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	distal-Epithelial-Proximal_Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 NWD1 ERICH3 CLXN PROM1 PCDHB1	3.85e-05	195	142	6	0e3f74e0877d33c11f048b9be8394596cf5c9c4c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	3.85e-05	195	142	6	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	BL-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.85e-05	195	142	6	07a6bcef6af93ed87df455dee624037cb75e011a
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.96e-05	196	142	6	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.96e-05	196	142	6	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.96e-05	196	142	6	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SESTD1 NEDD4L LAMB2 SYNPO UTRN AGRN	3.96e-05	196	142	6	eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.96e-05	196	142	6	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	Severe_COVID-19-Epithelial-Ciliated\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.96e-05	196	142	6	1cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	3.96e-05	196	142	6	69f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 NWD1 ERICH3 CLXN SYNE1 PROM1	4.08e-05	197	142	6	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	distal-Hematologic-Platelet/Megakaryocyte-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NWD1 ERICH3 CLXN ELL3 PROM1 FGF14	4.08e-05	197	142	6	751ffb8792058384079ebfe94872b3525f1aea84
ToppCell	distal-Hematologic-Platelet/Megakaryocyte\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NWD1 ERICH3 CLXN ELL3 PROM1 FGF14	4.08e-05	197	142	6	e28b1b154d9588dce07c123b36f7f01fa90a5fc1
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	4.08e-05	197	142	6	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	distal-3-Epithelial-Proximal_Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 NWD1 ERICH3 CLXN PROM1 PCDHB1	4.08e-05	197	142	6	15b4d1203943ce90a7083178d4a4284d9b323071
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 NWD1 ERICH3 CLXN NEK5 FGF14	4.08e-05	197	142	6	d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRLHR NWD1 GRM4 ITGB4 TGM5 BHMT	4.31e-05	199	142	6	f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	4.43e-05	200	142	6	52aef65f01b06cd98056f17977efe525aee6eb6f
ToppCell	Biopsy_Other_PF-Epithelial-Differentiating_Ciliated\|Biopsy_Other_PF / Sample group, Lineage and Cell type	NWD1 ERICH3 CLXN PROM1 NEK5 FGF14	4.43e-05	200	142	6	f7b4581d958afbd68f9045af619aaca0ab463439
ToppCell	Biopsy_Other_PF-Epithelial-Ciliated\|Biopsy_Other_PF / Sample group, Lineage and Cell type	DNAH3 NWD1 ERICH3 CLXN PROM1 NEK5	4.43e-05	200	142	6	721371698bce8890853fb6b6b01a2c20293b39e9
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	SH3RF1 HJURP GRM6 PROM1 BUB1B WDR62	4.43e-05	200	142	6	0bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	SH3RF1 HJURP GRM6 PROM1 BUB1B WDR62	4.43e-05	200	142	6	c9479452ab8c51139522383f745f02171ebbd7e2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	N4BP2L1 PLEKHG4 ETNPPL RENBP GRM4	8.08e-05	138	142	5	6b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PODNL1 CARMIL2 DUS3L GPR153 BUB1B	1.16e-04	149	142	5	65778f19599b4955c0a16f0121237656449431fb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LAMA5 XKR6 FFAR4 PPP2R2B SMAD3	1.23e-04	151	142	5	c1461d0dd622a081187eba77f454d2663df2732e
ToppCell	Leuk-UTI-Lymphocyte-T_NK-MAIT\|Leuk-UTI / Disease, Lineage and Cell Type	SETMAR SYNE1 XKR6 ATP9A GRM6	1.31e-04	153	142	5	ac3a1d1b5bf6009df818fd757dad7382d95c60dc
Drug	2-propylpentanoic acid; Down 200; 10000uM; MCF7; HG-U133A	TRAF6 SCAF8 RBM10 EVPL BCL3 CALHM2 BHMT POGLUT1 AGRN SMAD3	2.63e-07	188	140	10	345_DN
Drug	Mecamylamine hydrochloride [826-39-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A	CDC42BPA DCAF8 CALCOCO1 LAMB2 TMCO6 PTPRU VPS13D BRF2 TRMT61A	3.89e-06	198	140	9	7023_DN
Drug	paclitaxel; Up 200; 0.1uM; MCF7; HG-U133A	DNAH3 CLXN EVPL GRM4 BHMT PPP2R2B VPS13D GPR153 SMAD3	3.89e-06	198	140	9	640_UP
Drug	Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A	CDC42BPA PER1 FASTKD2 BMP1 GDPD5 LMAN1 GPR153 UTRN WDR62	3.89e-06	198	140	9	4782_UP
Drug	plakin	PLEKHG4 SYNE1 EVPL ITGB4 CTNNB1 UTRN	1.16e-05	82	140	6	CID000018752
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	LAMA5 BCL3 ZNF512B TBC1D31 ARHGAP12 AGRN SMAD3 TRMT61A	1.88e-05	184	140	8	1064_DN
Drug	0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A	MYBBP1A PFKFB3 CALHM2 BMP1 GDPD5 CTNNB1 KIF13A SMAD3	2.55e-05	192	140	8	3858_DN
Drug	Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	EVPL PTPRU NEB ITGB4 ZNF512B BMP1 KIF13A AGRN	2.75e-05	194	140	8	4804_DN
Drug	Bambuterol hydrochloride [81732-46-9]; Down 200; 10uM; MCF7; HT_HG-U133A	NEDD4L CALCOCO1 TMCO6 PTPRU ZNF512B AGRN WDR62 SMAD3	2.85e-05	195	140	8	7239_DN
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A	DNAH3 PTPRU NEB ZNF512B BMP1 VPS13D AGRN SMAD3	2.96e-05	196	140	8	3248_DN
Drug	arachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A	PODNL1 DNAH3 LAMB2 HUWE1 APOBEC3B ZNF512B PPP2R2B VPS13D	2.96e-05	196	140	8	443_DN
Drug	Nimesulide [51803-78-2]; Down 200; 13uM; MCF7; HT_HG-U133A	DCAF8 NEDD4L BCL3 CALHM2 BMP1 GDPD5 VPS13D GPR153	2.96e-05	196	140	8	7024_DN
Drug	Pyrimethamine [58-14-0]; Up 200; 16uM; PC3; HG-U133A	N4BP2L1 NEDD4L GRM6 BMP1 PJA2 VPS13D AGRN WDR62	2.96e-05	196	140	8	1894_UP
Drug	clozapine; Down 200; 10uM; MCF7; HT_HG-U133A	HNRNPDL DNAH3 CDC42BPA EVPL TMCO6 VPS13D WDR62 SMAD3	2.96e-05	196	140	8	6988_DN
Drug	clofibrate; Down 200; 100uM; MCF7; HG-U133A	PODNL1 DNAH3 TRAF6 HUWE1 TEX13B BHMT VPS13D RAPGEF3	3.07e-05	197	140	8	444_DN
Drug	celecoxib; Down 200; 10uM; PC3; HG-U133A	PODNL1 DNAH3 CLXN RBM10 TUT7 TMCO6 TGM4 RAPGEF3	3.07e-05	197	140	8	482_DN
Drug	Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A	DCAF8 PER1 EVPL SYNPO VPS16 BMP1 ARHGEF40 KIF13A	3.07e-05	197	140	8	3209_UP
Drug	Chlorzoxazone [95-25-0]; Down 200; 23.6uM; PC3; HT_HG-U133A	DNAH3 SYNPO ZNF512B VPS13D PLEKHG6 SMAD3 BRF2 TRMT61A	3.18e-05	198	140	8	2100_DN
Drug	Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A	PODNL1 BCL3 ITGB4 BMP1 KIF13A UTRN WDR62 SMAD3	3.18e-05	198	140	8	4812_UP
Drug	AG-012559 [369370-06-9]; Down 200; 10uM; MCF7; HT_HG-U133A	CDC42BPA DCAF8 BCL3 NEB GDPD5 UTRN BRF2 TRMT61A	3.18e-05	198	140	8	6889_DN
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	FLII CDC42BPA DCAF8 ZFP30 KIF16B TMCO6 VPS13D BRF2	3.30e-05	199	140	8	6963_DN
Disease	Giant axonal neuropathy	DCAF8 GAN	1.93e-05	2	130	2	cv:C5200933
Disease	Uterine Neoplasms	PROM1 SMAD3	6.80e-04	9	130	2	C0042138
Disease	left ventricular ejection fraction measurement	NEDD4L XKR6 PROM1	7.33e-04	40	130	3	EFO_0008373
Disease	Uterine Cancer	PROM1 SMAD3	8.47e-04	10	130	2	C0153567
Disease	smoking status measurement, ulcerative colitis	SYNPO SMAD3	1.46e-03	13	130	2	EFO_0000729, EFO_0006527
Disease	Left ventricular noncompaction	MIB2 MIB1	1.69e-03	14	130	2	C1960469
Disease	polyp of colon	LAMA5 PLEKHG6 SMAD3	1.95e-03	56	130	3	MONDO_0021400
Disease	body fat distribution	KIF1B XKR6 OSBPL7 TSGA10IP SMAD3	2.05e-03	202	130	5	EFO_0004341
Disease	low density lipoprotein cholesterol measurement, physical activity	N4BP2L1 PFAS UBXN2B	3.12e-03	66	130	3	EFO_0003940, EFO_0004611
Disease	Left Ventricle Remodeling	CTNNB1 SMAD3	3.83e-03	21	130	2	C0600520
Disease	Ventricular Remodeling	CTNNB1 SMAD3	3.83e-03	21	130	2	C0600519
Disease	Neutropenia	ELANE SMARCD2	3.83e-03	21	130	2	C0027947
Disease	respiratory system disease	BCL3 OSBPL7 IL6R SMAD3	3.94e-03	145	130	4	EFO_0000684
Disease	Colorectal Carcinoma	DNAH3 SYNE1 RBM10 PER1 PTPRU PROM1 BUB1B CTNNB1 SMAD3	3.99e-03	702	130	9	C0009402
Disease	Primary microcephaly	CTNNB1 WDR62	4.20e-03	22	130	2	C0431350

Protein segments in the cluster

Peptide	Gene	Start	Entry
RANRVLYQTRGQLHV	UPK3BL1	121	B0FP48
LERLQSQHRQFQARV	BUB1B	186	O60566
VRQLHREFLRAGSNV	BHMT	56	Q93088
FQRSQEIHQGLRKER	CCDC185	456	Q8N715
IQRFKGEHTRRSVEN	ERICH3	101	Q5RHP9
FQREQESKNQVHRRG	PPP2R2B	51	Q00005
GIIGVNRTRQVDNHV	DISP3	1016	Q9P2K9
QRQQVRPVIAFQGHR	ELL3	41	Q9HB65
SGLHRALRLQRFFQQ	ARHGEF40	866	Q8TER5
QKVRRVHFANARNAR	CXorf58	21	Q96LI9
GEVRAFLQENTHVRL	APOBEC3B	291	Q9UH17
QQTGRRVLTVDARNH	ABHD11	91	Q8NFV4
SRSLRHVALGRNFNV	CARMIL2	546	Q6F5E8
RRVLEAARRANQTGH	GRM4	291	Q14833
LRVVAHREQREGSLQ	AGRN	1976	O00468
THGIINRGRRANAEQ	APRG1	41	Q8IVJ8
GHVRIVSFLLRRNAN	ANKRD22	51	Q5VYY1
IRTGVQERVNLAHRL	DUS3L	436	Q96G46
FQVQQAVDLRRHTAR	BMP1	66	P13497
RLARQFRGHQDVITL	ETNPPL	121	Q8TBG4
TIRQGHGENRQREIE	HJURP	421	Q8NCD3
VQRRLQDLHRVISEG	KIF16B	1126	Q96L93
GEQFVVRANHQVLTR	NWD1	266	Q149M9
RGQLQSHGVQAREVR	RBM10	146	P98175
FQGETHRAQARRRDV	ERAS	21	Q7Z444
QHDLIQSGRFQRALV	QRICH2	401	Q9H0J4
RQGARRAQRHVTAQQ	HNRNPDL	51	O14979
FSVQRQNGEIHTLRQ	PCDHB1	616	Q9Y5F3
QVNGHNRLLVQRSEV	OVOS1	1061	Q6IE37
QEIAERGSQFIRNHL	POGLUT1	336	Q8NBL1
ARRILQHVQRDGQAV	RENBP	221	P51606
ARDVHNRIVIRGLNT	CTNNB1	581	P35222
HDQRFFLKTQGRREV	PIP5KL1	146	Q5T9C9
RLRLVRKGNEQHAFT	FLII	1241	Q13045
QQVFTRHINQIFIRG	LSM11	336	P83369
QGTFLLHQGIQRRIT	KIF1B	1281	O60333
EVHSRVLAANNVRRF	CALHM2	236	Q9HA72
RVLHFQKTQGLRRFA	EIF2B5	211	Q13144
HIIEQLRFRQSSVGN	RCE1	211	Q9Y256
HQIRVSQQDFRLFRT	FFAR4	251	Q5NUL3
VKHQGQQLFIESRAR	PER1	556	O15534
QDRLQRLFHERTFVQ	MYO18A	816	Q92614
RINRQRGVLFSEDQI	NEK5	91	Q6P3R8
QRQVRALTDRYHAVG	EVPL	721	Q92817
IDVGRRFLVNRVQDH	PFKFB3	216	Q16875
RFLVNRVQDHIQSRI	PFKFB3	221	Q16875
ARVFVQRFRLQHGLE	DCAF8	176	Q5TAQ9
ASGLIRQKRQAREQH	FGF14	6	Q92915
FQTLAVQVGRQADRR	GPR153	196	Q6NV75
LRQVFEGQNRIHLEI	LMAN1	331	P49257
QIQHLAGAIAERVRS	LAMB2	1551	P55268
EAVASLRRGHIQRLN	GDPD5	416	Q8WTR4
RNAVDAFRVNVIHAR	AP2M1	26	Q96CW1
AFRVNVIHARQQVRS	AP2M1	31	Q96CW1
RNQDIHVFRLVTNRG	ATP9A	696	O75110
QLQLVEGNFRHTETR	LAMA5	1761	O15230
ARRLQVAGEVNQRHF	PCDHGC4	61	Q9Y5F7
SEIQFNGHNRLLVQR	OVOS2	1261	Q6IE36
FLRNRAAAVHTAIRQ	EXOC8	431	Q8IYI6
GFSNHRKRLQAVQAR	HUWE1	266	Q7Z6Z7
LRGRQVRRFHVQLSN	ITGB4	1071	P16144
ARGSQQEHQLRRQVE	PCNT	2551	O95613
FNETLRITNIQRHQG	MDGA2	91	Q7Z553
RAGALHAQVERLVQQ	MYBBP1A	896	Q9BQG0
QRRQAATRDLFQAVG	PKD1L2	996	Q7Z442
QILFRHLRRVIENGE	ARHGAP12	781	Q8IWW6
RQHTQIVRLLVRAGA	MIB1	676	Q86YT6
FRVQNISRLQEGHLL	PTPRU	1321	Q92729
ILHLGRNRIRQVEAA	PODNL1	291	Q6PEZ8
FLRHINGQVRQGEEQ	PLEKHG6	346	Q3KR16
RTLQVLRAEHRGFQE	CBY2	381	Q8NA61
LRHVVQLRAQEEFGQ	IL6R	286	P08887
RRVLEAARQANLTGH	GRM6	286	O15303
RNDITGRFTRHLNII	DNAH3	2196	Q8TD57
FRLQLQQGLFRIRVH	GAN	581	Q9H2C0
GVLSARNNHELRNVI	B3GALNT2	56	Q8NCR0
NINRNHRGFKRVIQS	CC2D1B	761	Q5T0F9
LQHRQSLVRSAFRDG	BRF2	301	Q9HAW0
NVRAVRVVLGAHNLS	ELANE	76	P08246
QHVERIVRQVRAERG	CCDC177	316	Q9NQR7
VHRLVNLFQQGGREL	BCL3	151	P20749
AIGPVHQNRFIRQER	PPP1R18	81	Q6NYC8
IDSIVRQSRHQFGQE	SCAF8	66	Q9UPN6
RHVVQRQRVSGQVQA	POLRMT	511	O00411
RDILSRQQGDHVARI	CALCOCO1	216	Q9P1Z2
ENNIVHQARFFRRQT	OSBPL7	796	Q9BZF2
VHRITDRGDVRVQFN	MIB2	296	Q96AX9
FQLRQGHSRRVQVTV	KIF13A	1021	Q9H1H9
GQYRIHVASRQDNRR	RTP1	171	P59025
GLTRVRRFQQDDAHI	TARS1	451	P26639
YQAELQGIQHRVQAR	TSGA10IP	451	Q3SY00
ERGSTRVHALNNVNR	UTRN	81	P46939
TGLRDRLNQFRVHIT	TRIM49	276	P0CI25
RANRVLYQTRGQLHV	UPK3BL2	121	E5RIL1
LHGNRFNLVQRTAQA	TBC1D31	71	Q96DN5
VEGLRSIIHNFRANN	PLCB4	126	Q15147
ARVRRLHNVTNFLIG	PRLHR	86	P49683
LHVLAVHRAFRQQGR	AANAT	121	Q16613
RLQRQIADIHVAFQS	SYNE1	896	Q8NF91
QLVRQDEFVVRTGRH	PLEKHG4	926	Q58EX7
RRRQRVNEFTLESHG	SYNPO	176	Q8N3V7
AVSLRVQHRLQVQNG	SYNJ2BP	91	P57105
VHVLRTGFRILVDQQ	FASTKD2	286	Q9NYY8
GFVANHQVRTRIKRS	PROM1	176	O43490
EVLGFSEVQRRIHLQ	SETMAR	171	Q53H47
FRRGQVFHLRLVLNQ	TGM4	36	P49221
NDQLVAVISGRNRHV	CDC42BPA	1276	Q5VT25
RQIHLDTRLQVFRQN	MTRF1	31	O75570
AVGRHIFAKVQQRRQ	SMARCD2	506	Q92925
ARNAVRTVAAHNQER	SH3RF1	586	Q7Z6J0
QTGHELLSELQQRRF	SESTD1	211	Q86VW0
VGLDRNAFRNILHVT	CLXN	46	Q9HAE3
VRDQFNSHIQLVRNG	RNF214	411	Q8ND24
QASTERVLRAGRQLH	RAPGEF3	91	O95398
YLGIQSQRRKEHQRR	XKR6	261	Q5GH73
RSLSRGFNNHINLIR	TTC13	591	Q8NBP0
NLHVLFRTVQGEDRN	nan	41	Q6ZQY7
FRVRGQLNLHQRIHT	ZFP30	251	Q9Y2G7
QRFNSTHRILDVRNF	UBXN2B	271	Q14CS0
THRILDVRNFIVQSR	UBXN2B	276	Q14CS0
GNSFVRHNARQLTRV	PLCD3	571	Q8N3E9
NVNRNAAVELTRRHI	SMAD3	276	P84022
RPSRFQQQQGLRHVV	PFAS	291	O15067
TGLRDRLNQFRVHIT	TRIM49C	276	P0CI26
EVRNFQETIHQLEGR	TRAF6	291	Q9Y4K3
VAVRVQRGAQTQTRH	TRMT61A	26	Q96FX7
RRHFSMGNEVLQNRV	VPS16	116	Q9H269
ILDRERFTQVFGVHQ	TMEM186	196	Q96B77
RQRIQRYAQAFHTRG	TRPV6	681	Q9H1D0
LRQRVAQAFREGENT	UQCC2	31	Q9BRT2
RRGLQHPETQQTFIR	TMCO6	91	Q96DC7
ITVDHLLVRRGQAFN	TGM5	26	O43548
RVGNILHRLQTTFQE	WDR62	1411	O43379
RVRRTSAQVAVFHLQ	ZNF512B	681	Q96KM6
AGSVHVRIRRDANEQ	SLC30A6	296	Q6NXT4
SDRIFNRNSGLHQRV	ZNF233	431	A6NK53
TGLRDRLNQFRVHIT	TRIM49B	276	A6NDI0
NLHNNRAGRLAVRAT	WNT8A	161	Q9H1J5
AREHIRQNLESFIRQ	TUT7	1021	Q5VYS8
TGFNRHEAKQRSVQR	PJA2	331	O43164
RRNRSIIVDLFHGQL	USP6	671	P35125
VRFAHRQGQLQNRRV	TEX13B	76	Q9BXU2
QHFTQLQDVLGRQRA	VPS13D	1991	Q5THJ4
LRQQVTNHGRGTEVL	ZNF263	126	O14978
FNVQELARRNIHGVS	N4BP2L1	151	Q5TBK1
FVHVRRVNNVTSERL	NEB	5006	P20929
NIRQINQEAAHRRFR	NEDD4L	236	Q96PU5