Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC25A27 TMC2 SLC16A9 SLC43A1 CCDC51 SLC39A13 SLC5A11 SLC38A1 SLC7A8 SLC6A4 KCNH6 SLC7A1 SLC11A1 SLC50A1 CLDN17 MMGT1 LRP5 SLC25A29 ATP1A4 TMEM109 ATP1B3 UNC80 ABCC10

1.37e-06118012723GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC25A27 TMC2 SLC16A9 SLC43A1 CCDC51 SLC39A13 SLC5A11 SLC38A1 SLC7A8 SLC6A4 KCNH6 SLC7A1 SLC11A1 SLC50A1 CLDN17 MMGT1 LRP5 SLC25A29 ATP1A4 TMEM109 ATP1B3 UNC80 ABCC10

6.03e-06128912723GO:0005215
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC16A9 SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC25A29

1.49e-05831276GO:0015101
GeneOntologyMolecularFunctionnicotinic acid receptor activity

HCAR2 HCAR3

4.01e-0521272GO:0070553
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC25A27 TMC2 CCDC51 SLC39A13 SLC5A11 SLC38A1 SLC6A4 KCNH6 SLC11A1 MMGT1 ATP1A4 TMEM109 ATP1B3 UNC80

8.56e-0566412714GO:0008324
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC25A29

8.95e-05711275GO:0015179
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC25A27 TMC2 CCDC51 SLC39A13 SLC5A11 SLC38A1 SLC6A4 KCNH6 SLC11A1 CLDN17 MMGT1 ATP1A4 TMEM109 ATP1B3 UNC80

1.57e-0479312715GO:0015075
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TMC2 CCDC51 SLC39A13 SLC5A11 SLC38A1 SLC6A4 KCNH6 SLC11A1 MMGT1 ATP1A4 ATP1B3

1.91e-0446512711GO:0046873
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH1 DNAH8

1.91e-04181273GO:0008569
GeneOntologyMolecularFunctioncarbohydrate kinase activity

NAGK HK3 PFKP

3.07e-04211273GO:0019200
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC25A27 TMC2 CCDC51 SLC39A13 SLC5A11 SLC38A1 SLC6A4 KCNH6 SLC11A1 CLDN17 MMGT1 ATP1A4 ATP1B3 ABCC10

3.36e-0475812714GO:0015318
GeneOntologyMolecularFunctionnucleotide receptor activity

HCAR2 HCAR3 P2RY14

3.54e-04221273GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

HCAR2 HCAR3 P2RY14

3.54e-04221273GO:0001614
GeneOntologyMolecularFunctioncell adhesion molecule binding

EZR SWAP70 CALR RDX ADGRL1 UNC45A PFKP MSN SLC6A4 KIRREL3 NRXN2 CDH3

4.44e-0459912712GO:0050839
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC25A29

5.59e-041051275GO:0015171
GeneOntologyMolecularFunctionL-leucine transmembrane transporter activity

SLC43A1 SLC7A8

5.92e-0461272GO:0015190
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC25A27 TMC2 CCDC51 SLC39A13 SLC5A11 SLC38A1 SLC6A4 KCNH6 SLC11A1 MMGT1 ATP1A4 ATP1B3

6.65e-0462712712GO:0022890
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DNAH1 DNAH8

7.33e-04281273GO:0051959
GeneOntologyMolecularFunctionL-lysine transmembrane transporter activity

SLC7A1 SLC25A29

1.40e-0391272GO:0015189
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH1 DNAH8

1.67e-03371273GO:0045505
GeneOntologyMolecularFunctionbranched-chain amino acid transmembrane transporter activity

SLC43A1 SLC7A8

1.75e-03101272GO:0015658
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A4 ATP1B3

1.75e-03101272GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A4 ATP1B3

1.75e-03101272GO:0005391
GeneOntologyMolecularFunctionglycine transmembrane transporter activity

SLC38A1 SLC7A8

1.75e-03101272GO:0015187
GeneOntologyMolecularFunctionmanganese ion transmembrane transporter activity

SLC11A1 MMGT1

1.75e-03101272GO:0005384
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC16A9 SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC25A29

2.11e-032071276GO:0046943
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A4 ATP1B3

2.13e-03111272GO:0008556
GeneOntologyMolecularFunctioniron ion transmembrane transporter activity

SLC11A1 MMGT1

2.13e-03111272GO:0005381
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC16A9 SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC25A29

2.16e-032081276GO:0005342
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC43A1 SLC38A1 SLC7A8

2.25e-03411273GO:0015175
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

SLC7A8 LRP5

2.54e-03121272GO:0019534
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

SLC39A13 SLC11A1 MMGT1

2.75e-03441273GO:0046915
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC7A1 SLC25A29

2.99e-03131272GO:0061459
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC16A9 SLC5A11 SLC38A1 SLC7A8 SLC6A4 SLC11A1 ATP1A4 ATP1B3 ABCC10

3.47e-034771279GO:0022804
GeneOntologyBiologicalProcessamino acid transport

SLC43A1 SLC38A1 SLC7A8 SLC6A4 SLC7A1 SLC11A1 LRP5 PRKG1 SLC25A29

2.98e-061951259GO:0006865
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC11A1 SLC25A29

1.48e-05871256GO:1902475
GeneOntologyBiologicalProcesspositive regulation of early endosome to late endosome transport

EZR RDX MSN

1.78e-0591253GO:2000643
GeneOntologyBiologicalProcessregulation of anatomical structure size

ADCY10 EZR SWAP70 RDX NEB CCDC51 ADCY6 MSN DOCK5 SLC6A4 MYO3A WDR35 SMPD3 PRKG1

2.33e-0561812514GO:0090066
GeneOntologyBiologicalProcessregulation of protein localization to early endosome

EZR RDX MSN

2.53e-05101253GO:1902965
GeneOntologyBiologicalProcesspositive regulation of protein localization to early endosome

EZR RDX MSN

2.53e-05101253GO:1902966
GeneOntologyBiologicalProcessorganic cation transport

SLC16A9 SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC11A1 SLC25A29

2.93e-051451257GO:0015695
GeneOntologyBiologicalProcessglucose catabolic process

ADCY10 HK3 PFKP LRP5

4.05e-05321254GO:0006007
GeneOntologyBiologicalProcessvascular process in circulatory system

ADCY6 SLC38A1 DOCK5 SLC7A8 SLC6A4 SLC7A1 WDR35 SMPD3 PRKG1 ATP1A4

4.75e-0534412510GO:0003018
GeneOntologyBiologicalProcessL-amino acid transport

SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC11A1 SLC25A29

5.07e-051081256GO:0015807
GeneOntologyBiologicalProcessaromatic amino acid transport

SLC7A8 SLC7A1 SLC25A29

5.94e-05131253GO:0015801
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC16A9 SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC11A1 SLC25A29

6.18e-051631257GO:1905039
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC16A9 SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC11A1 SLC25A29

7.20e-051671257GO:1903825
GeneOntologyBiologicalProcesspositive regulation of protein localization to endosome

EZR RDX MSN

7.53e-05141253GO:1905668
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC11A1 SLC25A29

9.13e-051201256GO:0003333
GeneOntologyBiologicalProcessregulation of protein localization to endosome

EZR RDX MSN

9.37e-05151253GO:1905666
GeneOntologyBiologicalProcessL-arginine transmembrane transport

SLC7A1 SLC11A1 SLC25A29

9.37e-05151253GO:1903826
GeneOntologyBiologicalProcessprotein localization to early endosome

EZR RDX MSN

1.15e-04161253GO:1902946
GeneOntologyBiologicalProcesscirculatory system process

ADCY10 ADCY6 IFNG SLC38A1 DOCK5 SLC7A8 SLC6A4 KCNH6 SLC7A1 WDR35 LRP5 SMPD3 PRKG1 ATP1A4

1.45e-0473312514GO:0003013
GeneOntologyBiologicalProcessbasic amino acid transmembrane transport

SLC7A1 SLC11A1 SLC25A29

1.96e-04191253GO:1990822
GeneOntologyBiologicalProcesspositive regulation of adiponectin secretion

HCAR2 HCAR3

2.17e-0441252GO:0070165
GeneOntologyBiologicalProcessvaline transport

SLC43A1 SLC7A8

2.17e-0441252GO:0015829
GeneOntologyBiologicalProcessregulation of early endosome to late endosome transport

EZR RDX MSN

2.30e-04201253GO:2000641
GeneOntologyBiologicalProcessestablishment of epithelial cell apical/basal polarity

EZR LAMA1 MSN

2.67e-04211253GO:0045198
GeneOntologyBiologicalProcesshexose catabolic process

ADCY10 HK3 PFKP LRP5

2.99e-04531254GO:0019320
GeneOntologyBiologicalProcessMHC class II biosynthetic process

IFNG SLC11A1 CIITA

3.08e-04221253GO:0045342
GeneOntologyBiologicalProcessbasic amino acid transport

SLC7A1 SLC11A1 SLC25A29

3.08e-04221253GO:0015802
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception of sound

TMC2 STRC STRCP1

3.52e-04231253GO:0050910
GeneOntologyBiologicalProcessL-leucine import across plasma membrane

SLC43A1 SLC7A8

3.60e-0451252GO:1903801
GeneOntologyBiologicalProcessmonosaccharide catabolic process

ADCY10 HK3 PFKP LRP5

3.96e-04571254GO:0046365
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ATPSCKMT SLC25A27 TMC2 CCDC51 SLC39A13 IFNG SLC38A1 SLC6A4 KCNH6 SLC11A1 CLDN17 MMGT1 ATP1A4 TMEM109 ATP1B3 UNC80 ABCC10

4.06e-04111512517GO:0034220
GeneOntologyBiologicalProcessamino acid import across plasma membrane

SLC43A1 SLC38A1 SLC7A8 SLC7A1

4.23e-04581254GO:0089718
GeneOntologyBiologicalProcessestablishment of apical/basal cell polarity

EZR LAMA1 MSN

5.10e-04261253GO:0035089
GeneOntologyBiologicalProcessauditory receptor cell stereocilium organization

MYO3A STRC STRCP1

5.10e-04261253GO:0060088
GeneOntologyBiologicalProcessimport across plasma membrane

SLC43A1 IFNG SLC38A1 SLC7A8 SLC7A1 ATP1A4 ATP1B3

5.12e-042301257GO:0098739
GeneOntologyBiologicalProcesschemical homeostasis

SLC25A27 CCDC22 HK3 CALR SESN3 NCOA4 LYST ATP6AP1L ADCY6 SLC39A13 IFNG OTC SLC11A1 LRP5 ATP1A4 BACE2 ATP1B3 UNC80

5.31e-04124912518GO:0048878
GeneOntologyBiologicalProcessMHC class I protein complex assembly

CALR TAPBP

5.38e-0461252GO:0002397
GeneOntologyBiologicalProcessL-ornithine transmembrane transport

SLC7A1 SLC25A29

5.38e-0461252GO:1903352
GeneOntologyBiologicalProcessretinal blood vessel morphogenesis

LAMA1 LRP5

5.38e-0461252GO:0061304
GeneOntologyBiologicalProcessL-histidine transmembrane transport

SLC7A1 SLC25A29

5.38e-0461252GO:0089709
GeneOntologyBiologicalProcesspeptide antigen assembly with MHC class I protein complex

CALR TAPBP

5.38e-0461252GO:0002502
GeneOntologyBiologicalProcesscarbohydrate metabolic process

ADCY10 OMA1 NAGK HK3 PFKP COQ2 IFNG PHKA2 LRP5 SMPD3 PRKG1 MGAM2

5.64e-0464612512GO:0005975
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

ATPSCKMT SLC25A27 TMC2 CCDC51 SLC39A13 IFNG SLC38A1 SLC6A4 KCNH6 SLC11A1 MMGT1 ATP1A4 TMEM109 ATP1B3 UNC80

5.84e-0494212515GO:0098655
GeneOntologyBiologicalProcessestablishment of monopolar cell polarity

EZR LAMA1 MSN

6.37e-04281253GO:0061162
GeneOntologyBiologicalProcessestablishment or maintenance of monopolar cell polarity

EZR LAMA1 MSN

7.08e-04291253GO:0061339
GeneOntologyBiologicalProcessornithine transport

SLC7A1 SLC25A29

7.50e-0471252GO:0015822
GeneOntologyBiologicalProcesspolarized epithelial cell differentiation

EZR LAMA1 MSN

7.83e-04301253GO:0030859
GeneOntologyBiologicalProcessiron ion transmembrane transport

IFNG SLC11A1 MMGT1

7.83e-04301253GO:0034755
GeneOntologyCellularComponentstereocilium

TMC2 RDX ADCY6 MYO3A STRC STRCP1

4.10e-06691286GO:0032420
GeneOntologyCellularComponentstereocilium tip

TMC2 MYO3A STRC STRCP1

9.01e-06221284GO:0032426
GeneOntologyCellularComponentstereocilium bundle

TMC2 RDX ADCY6 MYO3A STRC STRCP1

9.03e-06791286GO:0032421
GeneOntologyCellularComponentapical plasma membrane

ADCY10 EZR SLC43A1 RDX ARHGEF18 MSN SLC5A11 SLC38A1 SLC7A8 SLC7A1 ATP1B3 CYP4F11

4.60e-0548712812GO:0016324
GeneOntologyCellularComponentactin-based cell projection

EZR TMC2 RDX ADCY6 MSN SLC7A8 MYO3A STRC STRCP1

5.48e-052781289GO:0098858
GeneOntologyCellularComponentapical part of cell

ADCY10 EZR SLC25A27 SLC43A1 RDX ARHGEF18 MSN SLC5A11 SLC38A1 SLC7A8 SLC7A1 ATP1B3 CYP4F11

7.13e-0559212813GO:0045177
GeneOntologyCellularComponentmicrovillus membrane

EZR ADCY6 MSN SLC7A8

8.43e-05381284GO:0031528
GeneOntologyCellularComponentcell tip

EZR RDX MSN

1.43e-04171283GO:0051286
GeneOntologyCellularComponentcell pole

EZR RDX MSN

2.37e-04201283GO:0060187
GeneOntologyCellularComponentmitochondrial inner membrane

ATPSCKMT OMA1 SLC25A27 FOXRED1 ACADVL SLC25A34 CCDC51 COQ2 OTC SLC25A43 SLC25A29 HERC2

2.90e-0459312812GO:0005743
GeneOntologyCellularComponentcluster of actin-based cell projections

EZR TMC2 RDX ADCY6 MYO3A STRC STRCP1

4.54e-042231287GO:0098862
GeneOntologyCellularComponentaxonemal dynein complex

DNHD1 DNAH1 DNAH8

4.67e-04251283GO:0005858
GeneOntologyCellularComponentorganelle inner membrane

ATPSCKMT OMA1 SLC25A27 FOXRED1 ACADVL SLC25A34 CCDC51 COQ2 OTC SLC25A43 SLC25A29 HERC2

6.74e-0465212812GO:0019866
GeneOntologyCellularComponentmicrovillus

EZR RDX ADCY6 MSN SLC7A8

9.66e-041231285GO:0005902
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

CALR ALG8 TAPBP

1.27e-03351283GO:0098553
GeneOntologyCellularComponentinner dynein arm

DNHD1 DNAH1

1.62e-03101282GO:0036156
GeneOntologyCellularComponentbasal part of cell

ADCY10 EZR MSN SLC38A1 SLC7A8 SLC7A1 ATP1B3 ABCC10

2.31e-033781288GO:0045178
GeneOntologyCellularComponentsodium:potassium-exchanging ATPase complex

ATP1A4 ATP1B3

2.36e-03121282GO:0005890
GeneOntologyCellularComponentlumenal side of membrane

CALR ALG8 TAPBP

3.17e-03481283GO:0098576
GeneOntologyCellularComponentMHC class I peptide loading complex

CALR TAPBP

3.23e-03141282GO:0042824
GeneOntologyCellularComponenturopod

EZR MSN

3.23e-03141282GO:0001931
GeneOntologyCellularComponent9+2 non-motile cilium

STRC STRCP1

3.23e-03141282GO:0097732
GeneOntologyCellularComponentkinocilium

STRC STRCP1

3.23e-03141282GO:0060091
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP6AP1L ATP1A4 ATP1B3

3.36e-03491283GO:0090533
GeneOntologyCellularComponentbasolateral plasma membrane

EZR MSN SLC38A1 SLC7A8 SLC7A1 ATP1B3 ABCC10

3.60e-033201287GO:0016323
GeneOntologyCellularComponentcell trailing edge

EZR MSN

3.71e-03151282GO:0031254
DomainERM_C_dom

EZR RDX MSN

1.19e-0641263IPR011259
DomainERM

EZR RDX MSN

1.19e-0641263PF00769
DomainERM

EZR RDX MSN

1.19e-0641263IPR011174
DomainMoesin_tail

EZR RDX MSN

1.03e-0571263IPR008954
DomainHCAR2/3_rcpt

HCAR2 HCAR3

4.52e-0521262IPR028017
DomainDynein_HC_stalk

DNHD1 DNAH1 DNAH8

1.03e-04141263IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH1 DNAH8

1.03e-04141263IPR013602
DomainDHC_N2

DNHD1 DNAH1 DNAH8

1.03e-04141263PF08393
DomainMT

DNHD1 DNAH1 DNAH8

1.03e-04141263PF12777
DomainDHC_fam

DNHD1 DNAH1 DNAH8

1.29e-04151263IPR026983
DomainDynein_heavy

DNHD1 DNAH1 DNAH8

1.29e-04151263PF03028
DomainDynein_heavy_dom

DNHD1 DNAH1 DNAH8

1.29e-04151263IPR004273
DomainRCC1

RCC2 HERC2 HERC5

3.14e-04201263PF00415
DomainEz/rad/moesin-like

EZR RDX MSN

3.65e-04211263IPR000798
DomainRCC1_1

RCC2 HERC2 HERC5

3.65e-04211263PS00625
DomainRCC1_2

RCC2 HERC2 HERC5

3.65e-04211263PS00626
DomainRCC1_3

RCC2 HERC2 HERC5

3.65e-04211263PS50012
Domain-

RCC2 HERC2 HERC5

4.20e-042212632.130.10.30
DomainReg_chr_condens

RCC2 HERC2 HERC5

4.20e-04221263IPR000408
Domain-

SLC25A27 SLC25A34 SLC25A43 SLC25A29

4.48e-045312641.50.40.10
DomainMito_carr

SLC25A27 SLC25A34 SLC25A43 SLC25A29

4.48e-04531264PF00153
DomainSOLCAR

SLC25A27 SLC25A34 SLC25A43 SLC25A29

4.48e-04531264PS50920
DomainMitochondrial_sb/sol_carrier

SLC25A27 SLC25A34 SLC25A43 SLC25A29

4.48e-04531264IPR018108
DomainMt_carrier_dom

SLC25A27 SLC25A34 SLC25A43 SLC25A29

4.48e-04531264IPR023395
DomainRCC1/BLIP-II

RCC2 HERC2 HERC5

4.81e-04231263IPR009091
DomainFERM_CS

EZR RDX MSN

5.47e-04241263IPR019747
DomainDUF3669_Znf

ZNF212 ZNF746

6.65e-0461262IPR022137
DomainDUF3669

ZNF212 ZNF746

6.65e-0461262PF12417
DomainFERM_C

EZR RDX MSN

6.96e-04261263PF09380
DomainFERM_PH-like_C

EZR RDX MSN

7.79e-04271263IPR018980
DomainFERM_C

EZR RDX MSN

7.79e-04271263SM01196
DomainAden_trnslctor

SLC25A27 SLC25A43 SLC25A29

8.68e-04281263IPR002113
DomainWD40_repeat_dom

KNTC1 GRWD1 EML2 LYST WDR53 SF3B3 WDR35 WDR82

9.24e-042971268IPR017986
DomainFERM_N

EZR RDX MSN

1.41e-03331263IPR018979
DomainFERM_N

EZR RDX MSN

1.41e-03331263PF09379
DomainWD40_repeat

GRWD1 EML2 LYST WDR53 WDR35 WDR82 HERC2

2.49e-032721267IPR001680
DomainWD_REPEATS_1

GRWD1 EML2 LYST WDR53 WDR35 WDR82 HERC2

2.81e-032781267PS00678
DomainWD_REPEATS_2

GRWD1 EML2 LYST WDR53 WDR35 WDR82 HERC2

2.87e-032791267PS50082
DomainWD_REPEATS_REGION

GRWD1 EML2 LYST WDR53 WDR35 WDR82 HERC2

2.87e-032791267PS50294
DomainAA_permease_2

SLC7A8 SLC7A1

3.35e-03131262PF13520
DomainAA/rel_permease1

SLC7A8 SLC7A1

3.35e-03131262IPR002293
DomainFERM_M

EZR RDX MSN

3.68e-03461263PF00373
DomainDynein_heavy_chain_D4_dom

DNAH1 DNAH8

3.90e-03141262IPR024317
DomainATPase_dyneun-rel_AAA

DNAH1 DNAH8

3.90e-03141262IPR011704
DomainAAA_8

DNAH1 DNAH8

3.90e-03141262PF12780
DomainAAA_5

DNAH1 DNAH8

3.90e-03141262PF07728
Domain-

EZR RDX MSN

4.41e-034912631.20.80.10
DomainFERM_central

EZR RDX MSN

4.41e-03491263IPR019748
DomainFERM_domain

EZR RDX MSN

4.41e-03491263IPR000299
DomainFERM/acyl-CoA-bd_prot_3-hlx

EZR RDX MSN

4.66e-03501263IPR014352
DomainFERM_1

EZR RDX MSN

4.66e-03501263PS00660
DomainFERM_2

EZR RDX MSN

4.66e-03501263PS00661
DomainFERM_3

EZR RDX MSN

4.66e-03501263PS50057
DomainBand_41_domain

EZR RDX MSN

4.66e-03501263IPR019749
DomainB41

EZR RDX MSN

4.66e-03501263SM00295
DomainEMI

EMILIN3 SSPOP

5.75e-03171262PS51041
Domain-

ADCY10 ADCY6

6.44e-031812623.30.70.1230
DomainNucleotide_cyclase

ADCY10 ADCY6

6.44e-03181262IPR029787
PathwayREACTOME_SENSORY_PROCESSING_OF_SOUND_BY_OUTER_HAIR_CELLS_OF_THE_COCHLEA

EZR TMC2 RDX MSN MYO3A STRC

2.40e-06551006M41823
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC25A29

2.81e-06321005MM14957
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC43A1 SLC38A1 SLC7A8 SLC7A1 SLC25A29

3.29e-06331005M188
PathwayREACTOME_SENSORY_PROCESSING_OF_SOUND

EZR TMC2 RDX MSN MYO3A STRC

1.73e-05771006M41822
PathwayWP_PTDINS45P2_IN_CYTOKINESIS_PATHWAY

EZR RDX MSN

7.27e-05121003M45558
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC43A1 SLC5A11 SLC38A1 SLC7A8 SLC7A1 SLC11A1 SLC50A1 SLC25A29

2.87e-042381008MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC43A1 SLC5A11 SLC38A1 SLC7A8 SLC7A1 SLC11A1 SLC50A1 SLC25A29

3.89e-042491008M5988
Pubmed

The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation.

EZR RDX MSN

5.34e-08313238479753
Pubmed

Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.

EZR RDX MSN

5.34e-083132318261459
Pubmed

Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.

EZR RDX MSN

5.34e-083132321659656
Pubmed

Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.

EZR RDX MSN

5.34e-083132319064715
Pubmed

Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.

EZR RDX MSN

5.34e-083132321864676
Pubmed

Differential expression of ezrin/radixin/moesin (ERM) and ERM-associated adhesion molecules in the blastocyst and uterus suggests their functions during implantation.

EZR RDX MSN

5.34e-083132314613898
Pubmed

Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.

EZR RDX MSN

5.34e-083132326555866
Pubmed

Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.

EZR RDX MSN

5.34e-083132323703860
Pubmed

Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.

EZR RDX MSN

5.34e-083132316889625
Pubmed

Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.

EZR RDX MSN

5.34e-083132321837648
Pubmed

Ezrin and moesin function together to promote T cell activation.

EZR RDX MSN

5.34e-083132319124745
Pubmed

Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.

EZR RDX MSN

5.34e-083132322132106
Pubmed

Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading.

EZR RDX MSN

5.34e-083132319321616
Pubmed

Deciphering brain-specific transcriptomic expression of Ezr, Rad and Msn genes in the development of Mus musculus.

EZR RDX MSN

5.34e-083132329906485
Pubmed

Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.

EZR RDX MSN

5.34e-083132331843195
Pubmed

Increased phosphorylation of ezrin/radixin/moesin proteins contributes to proliferation of rheumatoid fibroblast-like synoviocytes.

EZR RDX MSN

5.34e-083132321278069
Pubmed

Nuclear ERM (ezrin, radixin, moesin) proteins: regulation by cell density and nuclear import.

EZR RDX MSN

5.34e-083132315149851
Pubmed

ERM stable knockdown by siRNA reduced in vitro migration and invasion of human SGC-7901 cells.

EZR RDX MSN

5.34e-083132321352885
Pubmed

A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.

EZR RDX MSN

5.34e-08313231429901
Pubmed

ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion.

EZR RDX MSN

5.34e-083132332098334
Pubmed

Ezrin, Radixin, and Moesin (ERM) proteins function as pleiotropic regulators of human immunodeficiency virus type 1 infection.

EZR RDX MSN

5.34e-083132318295815
Pubmed

Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis.

EZR RDX MSN

5.34e-083132312360288
Pubmed

Dynamics and function of ERM proteins during cytokinesis in human cells.

EZR RDX MSN

5.34e-083132328889652
Pubmed

Control of adipogenesis by ezrin, radixin and moesin-dependent biomechanics remodeling.

EZR RDX MSN

5.34e-083132323116763
Pubmed

Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex.

EZR RDX MSN

5.34e-083132321451358
Pubmed

Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane.

EZR RDX MSN

5.34e-083132320679347
Pubmed

Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells.

EZR RDX MSN

5.34e-083132312385025
Pubmed

Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?

EZR RDX MSN

5.34e-083132325286001
Pubmed

Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.

EZR RDX MSN

5.34e-083132317977945
Pubmed

Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS.

EZR RDX MSN

5.34e-083132315252013
Pubmed

ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.

EZR RDX MSN

5.34e-083132332160548
Pubmed

The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.

EZR RDX MSN

5.34e-083132312734202
Pubmed

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.

EZR RDX MSN

2.13e-074132327793041
Pubmed

The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.

EZR RDX MSN

2.13e-074132315096511
Pubmed

Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.

EZR RDX MSN

2.13e-074132317237445
Pubmed

Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering.

EZR RDX MSN

2.13e-074132315178693
Pubmed

Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins.

EZR RDX MSN

2.13e-074132320660156
Pubmed

In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin.

EZR RDX MSN

2.13e-074132319129194
Pubmed

Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition.

EZR RDX MSN

2.13e-074132331018575
Pubmed

Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.

EZR RDX MSN

2.13e-074132324760896
Pubmed

Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.

EZR RDX MSN

2.13e-074132320855527
Pubmed

Functional binding interaction identified between the axonal CAM L1 and members of the ERM family.

EZR RDX MSN

2.13e-074132312070130
Pubmed

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

EZR RDX MSN

2.13e-074132319890007
Pubmed

The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins.

EZR RDX MSN

2.13e-074132328302370
Pubmed

Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.

EZR RDX MSN

2.13e-074132322685202
Pubmed

CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation.

EZR RDX MSN

2.13e-074132321289089
Pubmed

The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes.

EZR RDX MSN

2.13e-074132321148287
Pubmed

Rho-ROCK-dependent ezrin-radixin-moesin phosphorylation regulates Fas-mediated apoptosis in Jurkat cells.

EZR RDX MSN

2.13e-074132318941185
Pubmed

Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death.

EZR RDX MSN

2.13e-074132315818415
Pubmed

Proteomic profiling in pancreatic cancer with and without lymph node metastasis.

EZR RDX MSN

2.13e-074132319152423
Pubmed

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.

EZR RDX MSN

2.13e-074132319255442
Pubmed

Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.

EZR RDX MSN

2.13e-07413239890997
Pubmed

Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice.

EZR RDX MSN

5.31e-07513239464455
Pubmed

Activated ERM protein plays a critical role in drug resistance of MOLT4 cells induced by CCL25.

EZR RDX MSN

5.31e-075132323326330
Pubmed

Regulation of NK cell trafficking by CD81.

EZR RDX MSN

5.31e-075132319830727
Pubmed

A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

EZR RDX MSN

5.31e-075132323063725
Pubmed

Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells.

EZR RDX MSN

5.31e-075132321278261
Pubmed

Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.

EZR RDX MSN

5.31e-075132322891241
Pubmed

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.

EZR RDX MSN

5.31e-075132310806479
Pubmed

Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin.

EZR RDX MSN

5.31e-075132323019340
Pubmed

Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer).

EZR RDX MSN

5.31e-075132325575591
Pubmed

A novel role for BRCA1 in regulating breast cancer cell spreading and motility.

EZR RDX MSN

5.31e-075132321282464
Pubmed

Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.

EZR RDX MSN

1.06e-066132317515952
Pubmed

Expression of ezrin in subventricular zone neural stem cells and their progeny in adult and developing mice.

EZR RDX MSN

1.06e-066132323229862
Pubmed

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2.

EZR RDX MSN

1.06e-06613239472040
Pubmed

Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells.

EZR RDX MSN

1.06e-066132317349711
Pubmed

Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.

EZR RDX MSN

1.06e-066132326209696
Pubmed

Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.

EZR RDX MSN KIRREL3

1.38e-0622132434799561
Pubmed

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress.

EZR RDX MSN

1.85e-067132322291017
Pubmed

MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression.

EZR RDX MSN

1.85e-067132323264465
Pubmed

ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.

EZR MSN IFNG

2.95e-068132311728336
Pubmed

VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCε-dependent manner.

EZR RDX MSN

2.95e-068132324788249
Pubmed

Finding the Unicorn, a New Mouse Model of Midfacial Clefting.

EZR RDX MSN

4.41e-069132331940751
Pubmed

Radixin regulates cell migration and cell-cell adhesion through Rac1.

EZR RDX MSN

4.41e-069132322467863
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

DNHD1 ADGRG5 SLC25A27 SUMF2 TSPAN11 TMC2 ZG16B ZNF767P KIRREL3 CLDN17 WDR82 UGT3A2 BACE2 IL17RD ANGPTL5

5.37e-069851321512975309
Pubmed

Amino acid transport across mammalian intestinal and renal epithelia.

SLC43A1 SLC38A1 SLC7A8 SLC7A1

5.76e-0631132418195088
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

GRWD1 L3MBTL2 CALR UNC45A ECPAS SLC7A1 GET4 SF3B3 HERC2 TMEM109 ATP1B3 ARMC6

8.30e-066571321236180527
Pubmed

Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath.

EZR RDX MSN

1.15e-0512132318579745
Pubmed

Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling.

EZR RDX MSN

1.15e-0512132329361573
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

GRWD1 L3MBTL2 ACADVL CALR CHD1 TMEM214 UNC45A PFKP LCMT2 FAM171A1 SF3B3 PPP1R15B PANK4 MMGT1 HERC2 ATP1B3 ESPL1 HERC5

1.38e-0514871321833957083
Pubmed

Expression of ezrin and moesin related to invasion, metastasis and prognosis of laryngeal squamous cell carcinoma.

EZR MSN

1.43e-052132225299115
Pubmed

Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.

HCAR2 HCAR3

1.43e-052132228186140
Pubmed

Oxygen modulates iron homeostasis by switching iron sensing of NCOA4.

NCOA4 HERC2

1.43e-052132237059186
Pubmed

The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation.

HCAR2 HCAR3

1.43e-052132230154797
Pubmed

Ezrin and moesin expression within the developing human cerebrum and tuberous sclerosis-associated cortical tubers.

EZR MSN

1.43e-052132212111362
Pubmed

The role of HCA2 (GPR109A) in regulating macrophage function.

HCAR2 HCAR3

1.43e-052132223882124
Pubmed

Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.

HCAR2 HCAR3

1.43e-052132236891315
Pubmed

Down-regulation of MHC II in mesenchymal stem cells at high IFN-gamma can be partly explained by cytoplasmic retention of CIITA.

IFNG CIITA

1.43e-052132218209080
Pubmed

Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a.

HCAR2 HCAR3

1.43e-052132238007572
Pubmed

Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.

HCAR2 HCAR3

1.43e-052132224691444
Pubmed

cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.

SLC6A4 PRKG1

1.43e-052132219656393
Pubmed

Butyrate ameliorates caerulein-induced acute pancreatitis and associated intestinal injury by tissue-specific mechanisms.

HCAR2 HCAR3

1.43e-052132231347703
Pubmed

Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis.

HCAR2 HCAR3

1.43e-052132230659164
Pubmed

Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium.

HCAR2 HCAR3

1.43e-052132219223991
Pubmed

Perspectives for Ezrin and Radixin in Astrocytes: Kinases, Functions and Pathology.

EZR RDX

1.43e-052132231382374
Pubmed

Expression of ezrin and moesin in primary breast carcinoma and matched lymph node metastases.

EZR MSN

1.43e-052132228624994
Pubmed

Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice.

HCAR2 HCAR3

1.43e-052132223967184
Pubmed

Involvement of the Niacin Receptor GPR109a in the LocalControl of Glucose Uptake in Small Intestine of Type 2Diabetic Mice.

HCAR2 HCAR3

1.43e-052132226371038
Pubmed

Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.

HCAR2 HCAR3

1.43e-052132234653248
Pubmed

Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).

HCAR2 HCAR3

1.43e-052132219136666
Cytoband15q15.3

LCMT2 STRC STRCP1

5.10e-0525132315q15.3
Cytoband7q36.1

ZNF212 ZNF767P SSPOP ZNF746

6.43e-057413247q36.1
Cytoband12q24.31

KNTC1 HCAR2 DHX37 HCAR3

8.72e-0580132412q24.31
Cytoband5q14.2

ATP6AP1L TMEM167A

2.91e-04913225q14.2
Cytoband10q11.2

NCOA4 PRKG1

7.30e-0414132210q11.2
CytobandEnsembl 112 genes in cytogenetic band chr7q36

ZNF212 ZNF767P SSPOP ZNF746

1.19e-031591324chr7q36
GeneFamilySolute carriers

SLC25A27 SLC16A9 SLC43A1 SLC25A34 SLC39A13 SLC5A11 SLC38A1 SLC7A8 SLC6A4 SLC7A1 SLC11A1 SLC25A43 SLC50A1 SLC25A29

1.08e-093957714752
GeneFamilyHydroxy-carboxylic acid receptors

HCAR2 HCAR3

5.36e-053772200
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A4 ATP1B3

3.71e-0477721208
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY10 ADCY6

7.88e-041077253
GeneFamilyWD repeat domain containing

GRWD1 EML2 LYST WDR53 WDR35 WDR82

8.77e-04262776362
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

EZR RDX MSN

1.26e-03507731293
GeneFamilyDyneins, axonemal

DNAH1 DNAH8

2.34e-0317772536
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

NAGK TSPAN11 TM2D3 ADCY6 SLC39A13 SLC38A1 FAM171A1 TRIM11 SF3B3 SLC50A1 PPP1R15B PANK4 MMGT1 SMPD3 TMEM109 IL17RD SFT2D1

9.68e-0870313217MM1055
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

NAGK TSPAN11 TM2D3 ADCY6 SLC39A13 SLC38A1 FAM171A1 TRIM11 SF3B3 SLC50A1 PPP1R15B PANK4 SMPD3 TMEM109 IL17RD SFT2D1

3.49e-0768113216M5314
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

SWAP70 SESN3 ARHGEF18 SLC38A1 CIITA P2RY14 DNAH8

9.23e-071761317d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 NEB SSPOP FREM1 DNAH1 ATP1A4 UNC80

1.24e-0618413172cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 NEB SSPOP FREM1 DNAH1 ATP1A4 UNC80

1.24e-061841317ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 NEB SSPOP FREM1 DNAH1 ATP1A4 UNC80

1.24e-0618413172b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EZR SWAP70 NEB SLC38A1 CIITA SLC25A29 BACE2

1.34e-061861317d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 SLC38A1 FAM171A1 SLC7A1 PRKG1 SLC25A29 ATP1B3

1.43e-0618813174154f4787483c7e076e87a187733a9f666742c3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 SLC38A1 FAM171A1 SLC7A1 PRKG1 SLC25A29 ATP1B3

1.59e-06191131796b78b4e819ea6052334bfcbc7abbf35897df885
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 SLC6A4 SLC7A1 UGT3A2 SLC25A29 ATP1B3

5.72e-061511316f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 HK3 SLC5A11 SLC7A8 SLC11A1 SLC25A43

1.05e-05168131604e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 SLC38A1 SLC7A1 CIITA TMEM109 DNAH8

1.13e-0517013166210ee3bf29059e6149c047bb7e02c5f59441519
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

CALR LYST DNAAF8 SLC38A1 PPP1R15B P2RY14

1.37e-0517613163de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellmoderate-Lymphoid-B_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGRG5 SWAP70 SESN3 SLC38A1 CIITA DNAH8

1.88e-051861316fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR DOLPP1 SLC38A1 PHKA2 ALG8 CDH3

1.93e-05187131622fd1959879705a8c1128faa9de66696c4e0b7e3
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR DOLPP1 SLC38A1 PHKA2 ALG8 CDH3

1.93e-0518713165fae538de481367cf6d9a2d52190d77b99f6922c
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR DOLPP1 SLC38A1 PHKA2 ALG8 CDH3

1.93e-0518713160526c0a818cf28fd5b6ff65fe260e3c3a4a98a2a
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RDX FREM1 RASIP1 SMPD3 BACE2 ATP1B3

2.24e-05192131614a816ef116aa992f86edab411f043cf7d07fe04
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RDX FREM1 RASIP1 SMPD3 BACE2 ATP1B3

2.24e-051921316847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

EZR SWAP70 SLC25A43 CIITA PPP1R15B WDR35

2.31e-05193131608696a99309f5b088692ddac8cca35413b5e810d
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

PFKP FREM1 SLC38A1 FAM171A1 SLC7A1 SLC25A29

2.31e-051931316738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellT_cells-GZMK+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

LYST MSN IFNG SLC38A1 TMEM109 TAPBP

2.45e-051951316003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCellcontrol-Non-classical_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HK3 LYST DOCK5 HCAR3 SLC11A1 ATP1B3

2.52e-0519613161d71a5be652dd3281aba4f984f6ef84c993c5f63
ToppCellMultiple_Sclerosis-Myeloid-CD16_Mono|Multiple_Sclerosis / Disease, Lineage and Cell Type

NAGK HK3 LYST DOCK5 HCAR3 SLC11A1

2.52e-05196131683011b56780295dff5ded57064b07dcd2f19ea26
ToppCellremission-Non-classical_Monocyte|World / disease stage, cell group and cell class

NAGK HK3 ZG16B LYST HCAR3 SLC11A1

2.67e-0519813161c170655070acca00520b7cf9c510a04c0a90a8f
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC43A1 HCAR3 SLC11A1 CIITA PPP1R15B KDM2A

2.74e-051991316bbb4798d6a24e756fea744a151ba67c1bafbac9a
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADGRG5 FOXRED1 NAGK FAM178B KIRREL3 P2RY14

2.74e-051991316f197ab861767ee06aa47b86c537fb3d8c2b2bc3e
ToppCellMS-Multiple_Sclerosis-Myeloid-CD16+_Monocyte|Multiple_Sclerosis / Disease, condition lineage and cell class

NAGK HK3 LYST DOCK5 HCAR3 SLC11A1

2.82e-052001316add2f9fbada3a68662edc8c756af90cdc380295b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 SLC7A1 GET4 ATP1B3 HR

6.74e-0514413155665dd2839b6c8ddbf5ddb2d22e1ee6073f74c3b
ToppCellAdult-Immune-dendritic_cell-D231|Adult / Lineage, Cell type, age group and donor

NRXN2 CIITA P2RY14 SMPD3 MGAM2

7.43e-0514713157cc4f74dd7a86247db8dc049ed7eadeb53825a96
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 CIITA SLC25A29 DNAH8 CCDC188

8.18e-05150131553de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 CIITA SLC25A29 DNAH8 CCDC188

8.18e-051501315e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellLPS-IL1RA-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATPSCKMT SUMF2 DOLPP1 DOCK5 MYO3A

9.26e-051541315d55fb73461885e1e02061a344ff89624ef4de487
ToppCellLPS-IL1RA-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATPSCKMT SUMF2 DOLPP1 DOCK5 MYO3A

9.26e-05154131543735f7c58cac51855ded486ee8d8729a1b9909e
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EZR SWAP70 NEB CIITA BACE2

9.84e-051561315d81e78bec5c8a3f3ec9e1447ebab2c5805b815eb
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

ADCY10 SESN3 SLC5A11 ATP1A4 DNAH8

1.01e-041571315c44bd530e396b08f16f284e185dcb830843959ea
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 HK3 LYST SLC11A1 TMEM270

1.04e-041581315d43b335e6aa12d84a75b988fbd6127ff1f4af25c
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 HK3 LYST SLC11A1 TMEM270

1.04e-041581315ab12b29ce51ca2fcac469cc932391217d97145f9
ToppCellCOVID-19-APC-like-Monocytes|COVID-19 / group, cell type (main and fine annotations)

DHX37 TMEM214 CIITA P2RY14 UGT3A2

1.04e-041581315a0d94bd067424783863a48db20976d4c2043600c
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR ARHGEF18 PFKP DOCK5 CIITA

1.11e-0416013151f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC16A9 FAM178B LRP5 BACE2 ESPL1

1.14e-0416113158ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFNG SLC7A8 FAM171A1 RASIP1 P2RY14

1.28e-0416513155e7ee76f3dcddbd1b560bacd043f9001b0c18b5f
ToppCellIonocyte-iono-3|World / Class top

DNHD1 KNTC1 ADGRL1 PEX5 P2RY14

1.32e-0416613159c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC22 DNAAF8 MMGT1 ABCC10 HERC5

1.35e-041671315b742558ca92985db0a67c88f530bc375f3d3bb98
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 HK3 SLC7A8 SLC11A1 SLC25A43

1.39e-0416813154ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 SESN3 IFNG ATP1B3 TAPBP

1.43e-0416913152de213b083f57f47be58427c0ce127fee9f85caa
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 HK3 SLC7A8 SLC11A1 SLC25A43

1.43e-041691315454b92b9b67299a64278c010db033ca5b9d217a0
ToppCelldroplet-Lung-nan-21m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 HK3 PFKP SLC7A8 P2RY14

1.55e-0417213151b133be191252e7053faeacf9547730c3ae28d21
ToppCelldroplet-Lung-nan-21m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 HK3 PFKP SLC7A8 P2RY14

1.55e-041721315b3c53fd7e50f36de6a8585ae21d04e17932f262c
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EZR SWAP70 NEB SLC38A1 BACE2

1.60e-041731315f135cc9dcf34f33ced3210171ab40ae6d77cfae0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

EZR SWAP70 LYST CIITA PPP1R15B

1.60e-041731315d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EZR SWAP70 NEB SLC38A1 BACE2

1.60e-04173131523248019c819f6e38337dcc4edb763ef1992e89e
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HCAR2 HK3 PFKP SLC7A8 P2RY14

1.64e-04174131531f7127faabcb1092bb9827db625f57cf7d8240e
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HCAR2 HK3 PFKP SLC7A8 P2RY14

1.64e-0417413158a8e98e62c2859c004b44dbce6974c9639ebeac6
ToppCelldroplet-Liver-Npc-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 SLC16A9 NCOA4 SLC7A8 SLC11A1

1.68e-0417513151973fff0d7e1a94b31f461a39b91cc7984ebd8f1
ToppCellmild-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ADGRG5 DNAAF8 P2RY14 SMPD3 TMEM109

1.73e-04176131559a9c262c252b7d220a025837922d98e9d6b0a24
ToppCelldroplet-Liver-Npc-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 SLC16A9 NCOA4 SLC7A8 SLC11A1

1.73e-0417613151e430dffddd315d9a1cb4bd7fef5077656351c65
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC16A9 FAM178B SESN3 LRP5 BACE2

1.73e-041761315052b54c4337ca728974a106b6dbd3b72dd28eb23
ToppCellNS-moderate-d_16-33-Lymphoid-B_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGRG5 SWAP70 SESN3 CIITA DNAH8

1.78e-041771315320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|myeloid / Lineage, cell class and subclass

ADGRG5 KIRREL3 LRP5 P2RY14 SMPD3

1.82e-041781315f75591988bbbeba073b66329a3437cb9b02f7648
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG5 KIRREL3 CIITA P2RY14 SMPD3

1.82e-04178131527d9826b83be67b780901429470ceb013e9039c0
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ADGRL1 DOLPP1 TMEM214 PHKA2 PEX5

1.82e-0417813158151e5d73407fd9cba382b69a2bc707c81790c7f
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-tDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADGRG5 CIITA P2RY14 TMEM109 CCDC188

1.92e-0418013153d9f3e6f13e558279b4ef43e2c44c7c50d761745
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

ADGRG5 CALR PPP1R15B CPLANE1 TAPBP

1.92e-041801315974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HK3 SSPOP SLC7A8 SLC11A1 CIITA

1.92e-04180131566c7b02d85e32ba3e7530d0c4aff17e7525ccdd8
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

ADGRG5 CALR PPP1R15B CPLANE1 TAPBP

1.92e-041801315703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EZR SLC38A1 SLC7A1 SLC25A29 ATP1B3

1.97e-041811315c2a8ee8679a1d71fcbff792cd516d3ce114f3ca6
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EZR SWAP70 SESN3 ARHGEF18 CIITA

1.97e-041811315ce0e39114bf3bcbcce0fd4c0d70bedadd0853e1d
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ADGRG5 SLC38A1 KIRREL3 P2RY14 SMPD3

2.02e-04182131502e04294fce12591c32d7bd0e866a000ad1f836e
ToppCellnormal-na-Lymphocytic_B-B_mem-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

EZR SWAP70 CIITA BACE2 DNAH8

2.02e-041821315ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 SLC38A1 FAM171A1 PRKG1 SLC25A29

2.07e-041831315d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EZR SWAP70 NEB SLC38A1 BACE2

2.07e-04183131501664fce6b70a02c9d39d747b6a6aabc86d57bc2
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SLC43A1 UNC45A SLC50A1 CPLANE1 ZFP82

2.13e-0418413159cbfb9f09476b4d09eb8f92c6f21e449dabcfa98
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ADGRL1 DOLPP1 TMEM214 PHKA2 TMEM109

2.13e-0418413152c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCellfacs-Heart-RA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 ADGRL1 NRXN2 P2RY14 PRKG1

2.18e-041851315c4ef8d9f8b9769e887daac4efd9dc05738b28ae2
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EZR SWAP70 CIITA BACE2 DNAH8

2.18e-04185131591c9a3ea1afd97d35bd05648875d29b35fe09128
ToppCell(7)_MNP-(7)_DC_plasmacytoid|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ADGRG5 KIRREL3 P2RY14 SMPD3 TMEM109

2.18e-0418513159f67f652488e17075a372e2a2e1100f6d0af6d7d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PFKP SLC38A1 SLC7A1 SLC25A29 ATP1B3

2.18e-041851315a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCellfacs-Heart-RA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 ADGRL1 NRXN2 P2RY14 PRKG1

2.18e-04185131510ddf38d908525b4258f9d2da8be4c56ebc08ff4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 SLC38A1 FAM171A1 SLC7A1 PRKG1

2.23e-041861315d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell3'_v3-blood-Lymphocytic_B|blood / Manually curated celltypes from each tissue

SWAP70 CIITA P2RY14 BACE2 DNAH8

2.23e-0418613155624b1fc7eab9f505588fcc86a24d14f8bcbfef7
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|Dendritic_cell / Lineage, cell class and subclass

ADGRG5 KIRREL3 LRP5 P2RY14 SMPD3

2.23e-041861315858134580a09ed8a5eb6d6413d8ca9265904dfc1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 SLC38A1 FAM171A1 PRKG1 ATP1B3

2.23e-041861315b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

EZR SWAP70 CIITA BACE2 DNAH8

2.29e-041871315ea56cfca919a09db852b7ee5e42323f822962465
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 LYST IFNG SLC38A1 DOCK5

2.29e-041871315d17352f769c3c66601b65d060626eecff41b0482
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EZR SWAP70 CIITA BACE2 DNAH8

2.29e-04187131543f81863063509337bd56a67010c62fb51109bd5
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-pDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADGRG5 KIRREL3 P2RY14 SMPD3 TMEM109

2.29e-041871315bf64a6ef5062ec9a0f7095e8c97ce66bfc3bf179
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALR TMEM214 PFKP SLC50A1 P2RY14

2.35e-0418813157e27e49ec1eb02fb74c86ec2ccb84751bc778b21
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADGRG5 KIRREL3 P2RY14 SMPD3 TMEM109

2.35e-0418813156b0e0192519ea3ca49fb21de3da9a0a108fcb64d
ToppCelldroplet-Marrow-nan-21m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALR TMEM214 PFKP SLC50A1 P2RY14

2.35e-0418813154b14c3ad80507245564d5be96d33fd9361f67dd0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EZR SWAP70 SLC38A1 CIITA P2RY14

2.35e-041881315d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EZR SWAP70 NEB SLC38A1 BACE2

2.35e-041881315ef05d2fb17fd427d46d454e67073e0e1b45bb24c
ToppCell10x5'v1-week_12-13-Myeloid_DC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADGRG5 KIRREL3 P2RY14 SMPD3 TMEM109

2.35e-0418813150b19c35fdc2b9e064e8f03ef69ae08644794ec24
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EZR SWAP70 CIITA BACE2 DNAH8

2.35e-0418813159256c5f45c97df209bb9c322c3b557d4f726a333
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYST DNAH1 SMPD3 BACE2 ATP1B3

2.41e-0418913158e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EZR SWAP70 NEB SLC38A1 BACE2

2.41e-041891315ebaf722738c71d5f33f72341f801c6880f4aee14
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

HCAR2 MSN HCAR3 ATP1B3 CDH3

2.41e-041891315533c302df467d13ab639232daf4f8cafb808260b
ToppCell10x5'-Liver-Lymphocytic_B|Liver / Manually curated celltypes from each tissue

EZR SWAP70 SESN3 CIITA BACE2

2.41e-0418913151ebff8185060d78f27f8d887e9adaa5f8faf2196
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EZR SWAP70 CIITA BACE2 DNAH8

2.41e-041891315ac0203f17b481d608587113ea2de0f383b29ed27
ToppCellremission-B_memory|remission / disease stage, cell group and cell class

EZR SWAP70 CIITA BACE2 DNAH8

2.41e-041891315a7b434a5d2cc7c3952cb8f16d11219b691c6c2b6
ToppCellCOVID-19_Severe-Lymphoid_B-B_memory|COVID-19_Severe / Disease group, lineage and cell class

EZR SWAP70 CIITA BACE2 DNAH8

2.47e-041901315b6510c419a15ed049c0a0a6a6697b643668741c3
ToppCell10x3'2.3-week_17-19-Myeloid_DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADGRG5 KIRREL3 P2RY14 SMPD3 TMEM109

2.47e-0419013151687e133a88c3d036a33a4f8aeefe320a4f02c39
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

1.93e-0521302DOID:0110471 (implicated_via_orthology)
DiseaseColorectal Carcinoma

OMA1 HK3 CALR LAMA1 EML2 CHD1 PANK4 P2RY14 KDM2A UGT3A2 DNAH8 HR

6.69e-0570213012C0009402
Diseaseleishmaniasis (is_marker_for)

IFNG SLC6A4

1.15e-0441302DOID:9065 (is_marker_for)
Diseasepolycystic liver disease (is_implicated_in)

LRP5 ALG8

1.91e-0451302DOID:0050770 (is_implicated_in)
DiseasePolycystic liver disease

LRP5 ALG8

1.91e-0451302C0158683
DiseaseMYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding)

IFNG SLC11A1

8.47e-04101302C1834752
DiseaseMycobacterium tuberculosis, susceptibility to

IFNG SLC11A1

8.47e-04101302cv:C1834752
DiseaseMYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO

IFNG SLC11A1

8.47e-04101302607948
DiseaseDrug-induced depressive state

IFNG SLC6A4

1.24e-03121302C0338715
DiseaseLeishmaniasis, Visceral

IFNG SLC11A1

1.46e-03131302C0023290
Diseasejuvenile rheumatoid arthritis (is_implicated_in)

SLC11A1 CIITA

1.46e-03131302DOID:676 (is_implicated_in)
DiseaseParanoid Schizophrenia

CALR IFNG

1.46e-03131302C0036349
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

RDX MYO3A STRC

1.49e-03511303cv:CN043650
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

HCAR2 DNAH1 SLC38A1 SLC6A4 HCAR3

1.96e-032001305EFO_0004611, EFO_0020945
Diseaserheumatoid arthritis (is_implicated_in)

IFNG SLC11A1 CIITA

2.16e-03581303DOID:7148 (is_implicated_in)
Disease5-oxoproline measurement

PRKG1 DNAH8

2.22e-03161302EFO_0010988
DiseaseSynostotic Posterior Plagiocephaly

FREM1 WDR35

2.22e-03161302C1833340
DiseaseCraniosynostosis, Type 1

FREM1 WDR35

2.22e-03161302C4551902
DiseaseAcrocephaly

FREM1 WDR35

2.22e-03161302C0030044
DiseaseTrigonocephaly

FREM1 WDR35

2.22e-03161302C0265535
DiseaseScaphycephaly

FREM1 WDR35

2.22e-03161302C0265534
DiseaseSynostotic Anterior Plagiocephaly

FREM1 WDR35

2.22e-03161302C2931150
DiseaseMetopic synostosis

FREM1 WDR35

2.22e-03161302C1860819
Diseasehigh altitude adaptation

KNTC1 HCAR2

2.51e-03171302EFO_0009105
DiseaseBrachycephaly

FREM1 WDR35

2.51e-03171302C0221356
DiseaseCalcium channel blocker use measurement

SWAP70 ARHGEF18 SLC38A1 SLC7A1 ABCC10

2.58e-032131305EFO_0009930
DiseaseUlcerative Colitis

SLC11A1 HERC2 CDH3

2.74e-03631303C0009324
Diseasecommon carotid intimal medial thickness

ATPSCKMT SESN3 ATP6AP1L

3.26e-03671303EFO_0004860
Diseasesynophrys measurement

SLC6A4 LRP5 HERC2

3.40e-03681303EFO_0007906
DiseaseCraniosynostosis

FREM1 WDR35

3.47e-03201302C0010278
Diseasemean corpuscular hemoglobin concentration

KNTC1 ADGRG5 HCAR2 SWAP70 NCOA4 NEB ZNF767P SLC38A1 LINC01565 HCAR3 LRP5 ABCC10

3.60e-03110513012EFO_0004528
Diseasetriglyceride measurement, phospholipid measurement

HCAR2 DNAH1 SLC38A1 HCAR3

4.04e-031461304EFO_0004530, EFO_0004639
Diseaserosacea severity measurement

MYO3A PRKG1 HERC2 MGAM2

4.13e-031471304EFO_0009180
Diseasemultiple sclerosis (is_implicated_in)

IFNG SLC11A1 CIITA

4.15e-03731303DOID:2377 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
FFLPGIKWNGILGLA

BACE2

186

Q9Y5Z0
ASLALNLPGGGLKTW

ARHGEF18

111

Q6ZSZ5
GDAFLWKQLGANVLL

ADCY6

281

O43306
FLGALWLALSGEIKD

CIITA

716

P33076
GLTWAFGLLFINKES

ADGRL1

1061

O94910
FTAWKLATAGDQGLL

ARMC6

141

Q6NXE6
LGQGGWKLLGIVGSL

LINC01565

41

O15544
FGDLLGEFWLGLKKI

ANGPTL5

216

Q86XS5
LNGALQGGAWLLLEK

DNHD1

1726

Q96M86
GDILKFAGDALLALW

ADCY10

91

Q96PN6
DLGELLQAWGAGAKT

CCDC22

271

O60826
LLKDKAFLGGLNWAF

CHD1

596

O14646
GQKRELGAALFLGWA

CLDN17

156

P56750
WELLKEGFLLALTQG

NAGK

276

Q9UJ70
LLIFGATNWDLIGRK

RCC2

106

Q9P258
LVLDWLQGAGLGDIA

RASIP1

811

Q5U651
FGEQQGLLGVAAKAW

KLHL30

141

Q0D2K2
KDIFGGLAGFLRLWI

SLC7A8

111

Q9UHI5
KKGTELWLGVDALGL

RDX

211

P35241
GKLLLGILADFKWIN

SLC16A9

356

Q7RTY1
GLSKGFGLATQEPWI

ABCC10

661

Q5T3U5
QLALGLTFNWGALLG

COQ2

206

Q96H96
RFDQKLGTWLKSGLG

FAM171A1

246

Q5VUB5
LGTWLKSGLGLVHQE

FAM171A1

251

Q5VUB5
ILWSPGALGIEFLKG

IL17RD

96

Q8NFM7
SFLGGLALNEGVNWL

DOLPP1

61

Q86YN1
PFLLSGGDDGALKIW

GRWD1

321

Q9BQ67
NGSLKRVWILGSNGF

MGAM2

421

Q2M2H8
GQDALVLGFDWGKFL

L3MBTL2

171

Q969R5
LEFIFGLLGNGLALW

HCAR2

36

Q8TDS4
VFVWGLNDKDQLGGL

HERC2

2961

O95714
LRTLGKGDWFGEKAL

PRKG1

281

Q13976
NGLALDLQEGKLYWG

LRP5

506

O75197
EHKIGWLDSLGVQLG

KCNH6

431

Q9H252
LGWGSLLIILKNEGF

SLC43A1

31

O75387
QKDFLSGLDGEGLWS

HR

1031

O43593
TALLQGLAGRTWAGK

ECPAS

1571

Q5VYK3
LKGLTLSWIGDGNNI

OTC

186

P00480
LTGANLFRKEWSGLL

PFKP

131

Q01813
DYLLWNKLGATLANG

PEX5

521

P50542
LGRIFKGLAQSGSWG

DNAH8

1881

Q96JB1
LQHGWLTLRGGKGFL

FREM1

456

Q5H8C1
LGRAVGQWAGAKLLD

GHDC

406

Q8N2G8
LKSGAVWLVINLGSG

NRXN2

341

Q9P2S2
LSTDAQWGIRLGKLG

KNTC1

1401

P50748
DLQAGAVAGFKLLWV

SLC11A1

81

P49279
KKGSELWLGVDALGL

MSN

211

P26038
EDKGLAGGAALLSEW

SMPD3

101

Q9NY59
DLGNFWKAGEPLLQG

POM121L12

11

Q8N7R1
GLDQGILLNWTKGFK

HK3

616

P52790
LNGKLRSEGQGIWAL

PHF14

671

O94880
ALVKGLLAGNVFDWG

PANK4

556

Q9NVE7
LALSKGGELFAWGQN

HERC5

151

Q9UII4
GGNLKGLENWLLKSE

NCOA4

251

Q13772
ILGNWLDGLLGEKSY

DNAH1

2381

Q9P2D7
GSFSLLWKGAEALLE

ESPL1

146

Q14674
NWLLSGKQGDIFLGD

KDM2A

246

Q9Y2K7
GQGLWVSLKLLPGDL

DOCK5

396

Q9H7D0
LAGVLTTGELFLWNK

CPLANE1

76

Q9H799
GSSKGLAGQLWLLTL

CCDC188

331

H7C350
GFLKPWLGDGLLLSG

CYP4F11

126

Q9HBI6
GGVLGLSVAYWLKKL

FOXRED1

71

Q96CU9
FGVLGLDLWQVKSGT

CALR

311

P27797
WLEGDLGSLSFNTKG

DNAAF8

146

Q8IYS4
LAGKWDLGNLLLFNG

LYST

1661

Q99698
KLLLAGGTSGIVSWL

SLC25A29

191

Q8N8R3
GFVLWIKDGLALGVG

KIRREL3

76

Q8IZU9
LLDRNKTGLLGIFWK

TMEM167A

31

Q8TBQ9
ADNGTLFLGILKNWK

IFNG

46

P01579
FWTLEGGSLSKRQGL

EML2

231

O95834
WKGLVGIGLFALAHA

MMGT1

6

Q8N4V1
LWGSLLDGFEQKLQG

EMILIN3

311

Q9NT22
KKGTDLWLGVDALGL

EZR

211

P15311
RTWAGQGASLKLGDL

DHX37

841

Q8IY37
AIFGLEGLGLRDLWK

SEC14L6

151

B5MCN3
AGAWRLKQLLSFALG

SLC39A13

101

Q96H72
WKGGFILPVLGAVLA

CDH3

651

P22223
LLGELYGKAGLNQEW

PHKA2

806

P46019
LLSLLVGAWLKLGNG

SUMF2

11

Q8NBJ7
GEELKWPGVSFLLGN

SSPOP

2681

A2VEC9
ARADGLWGLQKGLAA

SLC25A34

61

Q6PIV7
WFLLLAVDGGKLTVF

GET4

241

Q7L5D6
KNWSLIGSVLGALIG

CCDC51

201

Q96ER9
LGAFGLLWDLIVDGI

FAM178B

341

Q8IXR5
LEFIFGLLGNGLALW

HCAR3

36

P49019
CLGEAFLNGKSIGLW

LAMA1

2271

P25391
NEKGAFWGLISGLLL

SLC5A11

476

Q8WWX8
GVLGLWNGLTANLLK

SLC25A43

261

Q8WUT9
GLLQKVLIWSQLFGG

PPP1R15B

76

Q5SWA1
FKILGDSGLGPWQLN

P2RY14

76

Q15391
NKWKLFLGLSSFGLL

OMA1

191

Q96E52
TGELGSKEALWGGLL

STRC

226

Q7RTU9
YTLNGSKLWISNGGL

ACADVL

241

P49748
LQKSNWGFLLTGLVG

ATPSCKMT

31

Q6P4H8
FKLGVLGWGAPALLV

ADGRG5

356

Q8IZF4
GNWFSALALGVTLLK

ALG8

11

Q9BVK2
CKQLFGGFSLLLWTG

ATP1A4

101

Q13733
GEFLGRTAKSWGLIL

ATP1B3

26

P54709
TKGLGLALLSAWEQL

TMEM270

106

Q6UE05
GTGLLWLPGGIKLFA

SFT2D1

51

Q8WV19
FGNQLEGKWAVLGTL

ZNF767P

56

Q75MW2
VKLGDSWDVKLGALG

ZG16B

91

Q96DA0
KEKGELSAGNGFWIL

TRIM11

366

Q96F44
GKELFGLDTLQKSLW

UNC80

2151

Q8N2C7
EWTGLKFSNDGKLIL

WDR82

196

Q6UXN9
LTKGALWAVFLLAGS

SLC7A1

521

P30825
EFLKTGGIAEWLNGL

SESN3

131

P58005
FWSLEDGLNRVLGLG

NUDT16L1

71

Q9BRJ7
FLLLGLFKALGWAAV

TAPBP

421

O15533
EVNNLGWLSYGALKG

SLC50A1

51

Q9BRV3
GWLSYGALKGDGILI

SLC50A1

56

Q9BRV3
GFANLTEGLKVWLGI

TMEM214

266

Q6NUQ4
AFAKILAEGGIRGLW

SLC25A27

176

O95847
LLTGGNDGKITLWDA

WDR53

256

Q7Z5U6
FLGFGAILWERKGCL

TSPAN11

76

A1L157
TGNKALWDRGLLNGA

SF3B3

1071

Q15393
WGLKLVIFLAGFVAL

TMEM109

161

Q9BVC6
GLKGLILKNDWESTG

ZFP82

111

Q8N141
FGNQLEGKWAVLGTL

ZNF212

86

Q9UDV6
TGELGSKEALWGGLL

STRCP1

226

A6NGW2
WELIELIGNGQFSKG

SWAP70

176

Q9UH65
FGNQLEGKWAVLGTL

ZNF746

56

Q6NUN9
GLKWQLGRIFALFLG

TMC2

501

Q8TDI7
AHVLNGKLLLVGGIW

LCMT2

591

O60294
FLLGLTLGTLWLCGK

UGT3A2

491

Q3SY77
LGDSGVWGLKKNFAL

TRIM23

81

P36406
ISALSWEGGGLKIAL

WDR35

306

Q9P2L0
WEGGGLKIALAVDSF

WDR35

311

Q9P2L0
RSKGLQDLGGISWQL

SLC6A4

241

P31645
LGLNSKWLSLKLGDA

ATP6AP1L

21

Q52LC2
GDKGTQRIWAALFLG

SLC38A1

446

Q9H2H9
LGQWREGLGKLFSFG

TM2D3

206

Q9BRN9
SWFEGQGLAGKLRAI

UNC45A

401

Q9H3U1
AGLDNWALGKTKVFL

MYO3A

1026

Q8NEV4
NSFLKGIGWIPIGSL

NEB

1441

P20929