Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates

DNMT3A DNMT3B

1.47e-052772GO:0051719
GeneOntologyMolecularFunctionDNA (cytosine-5-)-methyltransferase activity

DNMT3A DNMT3B

8.76e-054772GO:0003886
GeneOntologyMolecularFunctionDNA-methyltransferase activity

DNMT3A DNMT3B

3.04e-047772GO:0009008
GeneOntologyCellularComponentmuscle tendon junction

NRAP HMCN1

1.89e-046752GO:0005927
DomainADD

DNMT3A DNMT3B

9.50e-054752IPR025766
DomainC5_MeTfrase

DNMT3A DNMT3B

9.50e-054752IPR001525
DomainC5_DNA_meth_AS

DNMT3A DNMT3B

9.50e-054752IPR018117
DomainC5_MTASE_1

DNMT3A DNMT3B

9.50e-054752PS00094
DomainC5_MTASE_2

DNMT3A DNMT3B

9.50e-054752PS00095
DomainADD

DNMT3A DNMT3B

9.50e-054752PS51533
DomainSAM_MT_C5

DNMT3A DNMT3B

9.50e-054752PS51679
DomainDNA_methylase

DNMT3A DNMT3B

9.50e-054752PF00145
DomainDUF3398

DOCK11 DOCK8

2.36e-046752PF11878
DomainDOCK_C/D_N

DOCK11 DOCK8

2.36e-046752IPR021816
DomainEGF-like_CS

FAT2 HMCN1 HYAL1 LAMA5 EPHA10 LRP8

6.32e-04261756IPR013032
DomainEGF_2

FAT2 HMCN1 HYAL1 LAMA5 EPHA10 LRP8

6.85e-04265756PS01186
DomainDOCK_C

DOCK11 DOCK8

8.55e-0411752IPR010703
DomainDHR-1_domain

DOCK11 DOCK8

8.55e-0411752IPR027007
DomainDHR_2

DOCK11 DOCK8

8.55e-0411752PS51651
DomainDHR_1

DOCK11 DOCK8

8.55e-0411752PS51650
DomainDOCK-C2

DOCK11 DOCK8

8.55e-0411752PF14429
DomainDHR-2

DOCK11 DOCK8

8.55e-0411752IPR027357
DomainDHR-2

DOCK11 DOCK8

8.55e-0411752PF06920
DomainDOCK

DOCK11 DOCK8

8.55e-0411752IPR026791
DomainCadherin_CS

FAT2 PCDHAC1 PCDHA11 CDH3

9.70e-04109754IPR020894
DomainCADHERIN_1

FAT2 PCDHAC1 PCDHA11 CDH3

1.11e-03113754PS00232
DomainCadherin

FAT2 PCDHAC1 PCDHA11 CDH3

1.11e-03113754PF00028
DomainCADHERIN_2

FAT2 PCDHAC1 PCDHA11 CDH3

1.15e-03114754PS50268
Domain-

FAT2 PCDHAC1 PCDHA11 CDH3

1.15e-031147542.60.40.60
DomainCA

FAT2 PCDHAC1 PCDHA11 CDH3

1.18e-03115754SM00112
DomainCadherin-like

FAT2 PCDHAC1 PCDHA11 CDH3

1.22e-03116754IPR015919
DomainGlycoside_hydrolase_SF

CHIA HYAL1 SI

1.26e-0353753IPR017853
DomainCadherin

FAT2 PCDHAC1 PCDHA11 CDH3

1.30e-03118754IPR002126
DomainCNH

NRK MAP4K2

1.40e-0314752SM00036
DomainCNH

NRK MAP4K2

1.62e-0315752PF00780
DomainCNH

NRK MAP4K2

1.62e-0315752PS50219
DomainCNH_dom

NRK MAP4K2

1.62e-0315752IPR001180
DomainGal_mutarotase_SF_dom

MAN2B2 SI

2.08e-0317752IPR011013
DomainAMP-bd_C

ACSF3 ACSS2

2.08e-0317752IPR025110
DomainAMP-binding_C

ACSF3 ACSS2

2.08e-0317752PF13193
DomainPROTEIN_KINASE_ATP

NRK PAK4 STK40 IKBKB PLK4 MAP4K2 EPHA10

2.43e-03459757PS00107
DomainEGF

FAT2 HMCN1 HYAL1 LAMA5 LRP8

2.55e-03235755SM00181
DomainPWWP

DNMT3A DNMT3B

2.88e-0320752SM00293
DomainS_TKc

NRK PAK4 STK40 IKBKB PLK4 MAP4K2

3.20e-03359756SM00220
DomainEGF-like_dom

FAT2 HMCN1 HYAL1 LAMA5 LRP8

3.27e-03249755IPR000742
DomainPROTEIN_KINASE_ST

NRK PAK4 STK40 IKBKB PLK4 MAP4K2

3.33e-03362756PS00108
DomainProt_kinase_dom

NRK PAK4 STK40 IKBKB PLK4 MAP4K2 EPHA10

3.46e-03489757IPR000719
DomainPROTEIN_KINASE_DOM

NRK PAK4 STK40 IKBKB PLK4 MAP4K2 EPHA10

3.62e-03493757PS50011
DomainEGF_1

FAT2 HMCN1 HYAL1 LAMA5 LRP8

3.62e-03255755PS00022
DomainPWWP

DNMT3A DNMT3B

3.81e-0323752PF00855
DomainPWWP_dom

DNMT3A DNMT3B

3.81e-0323752IPR000313
DomainPWWP

DNMT3A DNMT3B

4.15e-0324752PS50812
DomainPkinase

NRK PAK4 STK40 IKBKB PLK4 MAP4K2

4.27e-03381756PF00069
DomainAMP-binding_CS

ACSF3 ACSS2

4.86e-0326752IPR020845
DomainAMP_BINDING

ACSF3 ACSS2

5.62e-0328752PS00455
DomainHomeobox_metazoa

HOXA7 HOXA9 CDX1

5.69e-0390753IPR020479
DomainCatenin_binding_dom

CDH3 TCF7L1

6.02e-0329752IPR027397
Domain-

CDH3 TCF7L1

6.02e-03297524.10.900.10
DomainKinase-like_dom

NRK PAK4 STK40 IKBKB PLK4 MAP4K2 EPHA10

6.03e-03542757IPR011009
DomainAMP-binding

ACSF3 ACSS2

6.44e-0330752PF00501
DomainAMP-dep_Synth/Lig

ACSF3 ACSS2

6.44e-0330752IPR000873
DomainHomeobox_CS

HOXA7 HOXA9 CDX1 PBX2

6.68e-03186754IPR017970
DomainAlkaline_phosphatase_core

STS PIGO

6.86e-0331752IPR017850
DomainAlkaline_Pase-like_a/b/a

STS PIGO

6.86e-0331752IPR017849
Pubmed

Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ.

MKI67 DNMT3A DNMT3B

1.04e-07577328425913
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHAC1 PCDHA11 DNMT3A DNMT3B

2.28e-072477424698270
Pubmed

Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina.

MKI67 DNMT3A DNMT3B

2.26e-061277321452232
Pubmed

Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b.

DNMT3A DNMT3B

4.84e-06277212869530
Pubmed

Local chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylase.

DNMT3A DNMT3B

4.84e-06277226098813
Pubmed

The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin.

DNMT3A DNMT3B

4.84e-06277215456878
Pubmed

Liver-specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high-fat diet-fed male mice.

DNMT3A DNMT3B

4.84e-06277238795327
Pubmed

Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA.

DNMT3A DNMT3B

4.84e-06277219620278
Pubmed

Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization.

DNMT3A DNMT3B

4.84e-06277215757890
Pubmed

Dnmt3a deficiency in the skin causes focal, canonical DNA hypomethylation and a cellular proliferation phenotype.

DNMT3A DNMT3B

4.84e-06277233846253
Pubmed

DNA methylation and demethylation in mammals.

DNMT3A DNMT3B

4.84e-06277221454628
Pubmed

Profound flanking sequence preference of Dnmt3a and Dnmt3b mammalian DNA methyltransferases shape the human epigenome.

DNMT3A DNMT3B

4.84e-06277215854647
Pubmed

DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.

DNMT3A DNMT3B

4.84e-06277227468168
Pubmed

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.

DNMT3A DNMT3B

4.84e-06277217890317
Pubmed

The influence of DNMT3A and DNMT3B gene polymorphisms on acute myeloid leukemia risk in a Moroccan population.

DNMT3A DNMT3B

4.84e-06277232912818
Pubmed

Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome.

DNMT3A DNMT3B

4.84e-06277216501171
Pubmed

Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.

DNMT3A DNMT3B

4.84e-06277225639876
Pubmed

Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases.

DNMT3A DNMT3B

4.84e-06277211919202
Pubmed

Epigenetic inheritance is unfaithful at intermediately methylated CpG sites.

DNMT3A DNMT3B

4.84e-06277237660134
Pubmed

De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state.

DNMT3A DNMT3B

4.84e-06277221576263
Pubmed

Dissect the DNMT3A- and DNMT3B-mediated DNA Co-methylation through a Covalent Complex Approach.

DNMT3A DNMT3B

4.84e-06277231726062
Pubmed

Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B.

DNMT3A DNMT3B

4.84e-06277232968275
Pubmed

Negative Evidence for a Functional Role of Neuronal DNMT3a in Persistent Pain.

DNMT3A DNMT3B

4.84e-06277230258352
Pubmed

Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.

DNMT3A DNMT3B

4.84e-06277212897133
Pubmed

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.

DNMT3A DNMT3B

4.84e-06277232620778
Pubmed

Centromere mitotic recombination in mammalian cells.

DNMT3A DNMT3B

4.84e-06277218541703
Pubmed

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.

DNMT3A DNMT3B

4.84e-06277210555141
Pubmed

DNA methyltransferase 3A promoter polymorphism is associated with the risk of human spontaneous abortion after assisted reproduction techniques and natural conception.

DNMT3A DNMT3B

4.84e-06277227817038
Pubmed

Hidden Markov Modelling Reveals Neighborhood Dependence of Dnmt3a and 3b Activity.

DNMT3A DNMT3B

4.84e-06277231027045
Pubmed

A single amino acid substitution confers enhanced methylation activity of mammalian Dnmt3b on chromatin DNA.

DNMT3A DNMT3B

4.84e-06277220507910
Pubmed

Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes.

DNMT3A DNMT3B

4.84e-06277223611774
Pubmed

Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development.

DNMT3A DNMT3B

4.84e-06277232581223
Pubmed

Chromatin targeting of de novo DNA methyltransferases by the PWWP domain.

DNMT3A DNMT3B

4.84e-06277214998998
Pubmed

Association of DNA methyltransferases 3A and 3B polymorphisms, and plasma folate levels with the risk of urothelial carcinoma.

DNMT3A DNMT3B

4.84e-06277225126948
Pubmed

Dynamic expression of DNMT3a and DNMT3b isoforms during male germ cell development in the mouse.

DNMT3A DNMT3B

4.84e-06277216725135
Pubmed

Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance.

DNMT3A DNMT3B

4.84e-06277221304883
Pubmed

Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.

DNMT3A DNMT3B

4.84e-06277226993463
Pubmed

piRNA-6426 increases DNMT3B-mediated SOAT1 methylation and improves heart failure.

SOAT1 DNMT3B

4.84e-06277235354120
Pubmed

DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a/b-independent de novo methylation.

DNMT3A DNMT3B

4.84e-06277212370304
Pubmed

Expression and potential role of microRNA-29b in mouse early embryo development.

DNMT3A DNMT3B

4.84e-06277225766529
Pubmed

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases.

DNMT3A DNMT3B

4.84e-0627729662389
Pubmed

Deoxyribonucleic acid methyl transferases 3a and 3b associate with the nuclear orphan receptor COUP-TFI during gene activation.

DNMT3A DNMT3B

4.84e-06277217579209
Pubmed

Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epidermal Stem Cell Homeostasis.

DNMT3A DNMT3B

4.84e-06277227476967
Pubmed

Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences.

DNMT3A DNMT3B

4.84e-06277232543182
Pubmed

Mutation screening of HOXA7 and HOXA9 genes in Chinese women with Müllerian duct abnormalities.

HOXA7 HOXA9

4.84e-06277225246116
Pubmed

Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects.

DNMT3A DNMT3B

4.84e-06277219228594
Pubmed

Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues.

DNMT3A DNMT3B

4.84e-06277231665063
Pubmed

The human DNA methyltransferases DNMT3A and DNMT3B have two types of promoters with different CpG contents.

DNMT3A DNMT3B

4.84e-06277212359337
Pubmed

Benzo[a]pyrene diol epoxide suppresses retinoic acid receptor-beta2 expression by recruiting DNA (cytosine-5-)-methyltransferase 3A.

DNMT3A DNMT3B

4.84e-06277220426865
Pubmed

An investigation of genetic variability of DNA methyltransferases DNMT3A and 3B does not provide evidence for a major role in the pathogenesis of panic disorder and dimensional anxiety phenotypes.

DNMT3A DNMT3B

4.84e-06277232468273
Pubmed

High expression of DNMT3A and DNMT3B regulatory factors of TGFB in non-neoplastic liver tissues of HCC.

DNMT3A DNMT3B

4.84e-06277237807334
Pubmed

Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor.

NRK MKI67

4.84e-06277221715335
Pubmed

Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse.

DNMT3A DNMT3B

4.84e-06277225476147
Pubmed

Cloning, expression and chromosome locations of the human DNMT3 gene family.

DNMT3A DNMT3B

4.84e-06277210433969
Pubmed

DNA methyltransferase-3-dependent nonrandom template segregation in differentiating embryonic stem cells.

DNMT3A DNMT3B

4.84e-06277224127215
Pubmed

DNA methylation affects nuclear organization, histone modifications, and linker histone binding but not chromatin compaction.

DNMT3A DNMT3B

4.84e-06277217485486
Pubmed

DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma.

DNMT3A DNMT3B

4.84e-06277234831178
Pubmed

DNMT3A/3B overexpression might be correlated with poor patient survival, hypermethylation and low expression of ESR1/PGR in endometrioid carcinoma: an analysis of The Cancer Genome Atlas.

DNMT3A DNMT3B

4.84e-06277230614867
Pubmed

Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.

DNMT3A DNMT3B

4.84e-06277225130491
Pubmed

HOXA9 promotes homotypic and heterotypic cell interactions that facilitate ovarian cancer dissemination via its induction of P-cadherin.

HOXA9 CDH3

4.84e-06277225023983
Pubmed

Assignment of cytosine-5 DNA methyltransferases Dnmt3a and Dnmt3b to mouse chromosome bands 12A2-A3 and 2H1 by in situ hybridization.

DNMT3A DNMT3B

4.84e-06277210575238
Pubmed

Two models of Smad4 and Hoxa9 complex are proposed: structural and interactional perspective.

HOXA9 SMAD4

4.84e-06277221294585
Pubmed

Do mutations in DNMT3A/3B affect global DNA hypomethylation among benzene-exposed workers in Southeast China?: Effects of mutations in DNMT3A/3B on global DNA hypomethylation.

DNMT3A DNMT3B

4.84e-06277228945286
Pubmed

Hoxa9 regulates Flt3 in lymphohematopoietic progenitors.

HOXA7 HOXA9

4.84e-06277220971928
Pubmed

DNA methyltransferase 3a limits the expression of interleukin-13 in T helper 2 cells and allergic airway inflammation.

DNMT3A DNMT3B

4.84e-06277222190484
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHAC1 PCDHA11 CNTN2

8.31e-061877315570159
Pubmed

Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation.

HOXA7 HOXA9 CDX1

8.31e-06187739291463
Pubmed

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis.

MKI67 LAMA5 CDH3

9.86e-061977327234308
Pubmed

Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium.

MKI67 DNMT3A DNMT3B

1.16e-052077326023099
Pubmed

The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation.

CDX1 MKI67 SI

1.16e-05207739203584
Pubmed

Expression and regulation of DNA methyltransferases in human endometrium.

DNMT3A DNMT3B

1.45e-05377220970125
Pubmed

Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.

DNMT3A DNMT3B

1.45e-05377215456861
Pubmed

Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.

DNMT3A DNMT3B

1.45e-05377215671018
Pubmed

DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells.

DNMT3A DNMT3B

1.45e-05377230321403
Pubmed

Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system.

DNMT3A DNMT3B

1.45e-05377215672446
Pubmed

Expression and clinicopathological significance of DNA methyltransferase 1, 3A and 3B in tamoxifen-treated breast cancer patients.

DNMT3A DNMT3B

1.45e-05377230359738
Pubmed

High expression of DNA methyltransferases in primary human medulloblastoma.

DNMT3A DNMT3B

1.45e-05377227543768
Pubmed

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

DNMT3A DNMT3B

1.45e-05377223100393
Pubmed

DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo.

DNMT3A DNMT3B

1.45e-05377220838592
Pubmed

DNA methyltransferases 1, 3a, and 3b overexpression and clinical significance in gastroenteropancreatic neuroendocrine tumors.

DNMT3A DNMT3B

1.45e-05377220381114
Pubmed

De novo DNA Methyltransferases Dnmt3a and Dnmt3b regulate the onset of Igκ light chain rearrangement during early B-cell development.

DNMT3A DNMT3B

1.45e-05377226059604
Pubmed

Targeting DNA methylation for treating triple-negative breast cancer.

DNMT3A DNMT3B

1.45e-05377231755366
Pubmed

Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers.

DNMT3A DNMT3B

1.45e-05377215721400
Pubmed

Epigenetic regulation of myofibroblast differentiation by DNA methylation.

DNMT3A DNMT3B

1.45e-05377220489138
Pubmed

Mitochondrial genome undergoes de novo DNA methylation that protects mtDNA against oxidative damage during the peri-implantation window.

DNMT3A DNMT3B

1.45e-05377235858425
Pubmed

DNA methyltransferases control telomere length and telomere recombination in mammalian cells.

DNMT3A DNMT3B

1.45e-05377216565708
Pubmed

DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction.

DNMT3A DNMT3B

1.45e-05377215105426
Pubmed

Progressive up-regulation of genes encoding DNA methyltransferases in the colorectal adenoma-carcinoma sequence.

DNMT3A DNMT3B

1.45e-05377217538945
Pubmed

Temporal regulation of the expression of syncytin (HERV-W), maternally imprinted PEG10, and SGCE in human placenta.

SGCE ERVW-1

1.45e-05377212620933
Pubmed

[Biochemistry of DNA methyltransferases].

DNMT3A DNMT3B

1.45e-05377218536344
Pubmed

Superovulation alters DNA methyltransferase protein expression in mouse oocytes and early embryos.

DNMT3A DNMT3B

1.45e-05377229164502
Pubmed

B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.

DNMT3A DNMT3B

1.45e-05377229765016
Pubmed

Gene-gene and gene-sex epistatic interactions of DNMT1, DNMT3A and DNMT3B in autoimmune thyroid disease.

DNMT3A DNMT3B

1.45e-05377227237591
Pubmed

Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases.

DNMT3A DNMT3B

1.45e-05377212145218
Pubmed

Aberrant expression of deoxyribonucleic acid methyltransferases DNMT1, DNMT3A, and DNMT3B in women with endometriosis.

DNMT3A DNMT3B

1.45e-05377217081533
Pubmed

DNA methyltransferases in hematological malignancies.

DNMT3A DNMT3B

1.45e-05377232994141
Pubmed

DNA Methyltransferases as Potential Biomarkers for HCV Related Hepatocellular Carcinoma.

DNMT3A DNMT3B

1.45e-05377233247696
Pubmed

Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos.

DNMT3A DNMT3B

1.45e-05377219509302
Pubmed

Targeting of 5-aza-2'-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme.

DNMT3A DNMT3B

1.45e-05377220348135
Pubmed

The 'de novo' DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium.

DNMT3A DNMT3B

1.45e-05377226808831
Cytoband1p34

UROD LRP8

1.44e-03328021p34
Cytoband7p15.2

HOXA7 HOXA9

2.59e-03438027p15.2
GeneFamilyHOXL subclass homeoboxes

HOXA7 HOXA9 CDX1

4.24e-0452513518
GeneFamilyPWWP domain containing

DNMT3A DNMT3B

1.74e-03225121147
GeneFamilyAcyl-CoA synthetase family

ACSF3 ACSS2

2.43e-032651240
CoexpressionLIU_CDX2_TARGETS_UP

HOXA7 HOXA9 CDX1 SI DNMT3B

6.20e-0835785M16637
CoexpressionGSE17721_CTRL_VS_CPG_8H_BMDC_DN

HOXA9 NRAP STK40 CDH3 PLK4 LRP8

2.98e-05200786M3768
CoexpressionFINETTI_BREAST_CANCERS_KINOME_BLUE

NRK IKBKB EPHA10

3.24e-0521783M2862
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 MYO7B NRK ADAMTS16 EPHA10 CNTN2

8.03e-071847762cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 MYO7B NRK ADAMTS16 EPHA10 CNTN2

8.03e-07184776ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 MYO7B NRK ADAMTS16 EPHA10 CNTN2

8.03e-071847762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HOXA9 PRCP TCF7L1 RYR1 DNMT3B

8.33e-061597756115cb03c2ad08e4c1b65893d522f685ff0bc692
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HOXA9 PRCP TCF7L1 RYR1 DNMT3B

8.58e-06160775a90eb621481fd07a821495db07d1032e109fd386
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA7 MAN2B2 PRCP ANKRD33B ALG13

1.25e-051737750a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO7B EHHADH SLC22A2 SSTR2 ANKRD33B

1.56e-051817756980ea624151da32b7f537f263e40fcb87a02e81
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|lymph-node_spleen / Manually curated celltypes from each tissue

HOXA7 HOXA9 EHHADH MKI67 ACSS2

1.78e-0518677517eec1efad1f5e9ced1eb6bc9eb5dd7ded789c61
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 CYP27C1 NRK ADAMTS16 CDH3

1.82e-0518777577886f99c229610abd28c4c370d2c7d1536c9782
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA9 NRK ADAMTS16 SGCE UROD

2.34e-051977752744cc94883c5d0424677cf5093bbab622933e9b
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT2 CYP27C1 MKI67 CDH3 PLK4

2.34e-0519777525bbe270d0897b9b1bd00d205f66efd1def81b99
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HOXA7 HOXA9 HMCN1 ADAMTS16 MAP4K2

2.40e-051987757d2fe57e0f9311ac1e6854402ebc154306eb1ba5
ToppCellproximal-Epithelial-Proliferating_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAT2 MKI67 ARHGAP11A CDH3 PLK4

2.46e-05199775521ff4ae3437c8ba477a0a42b9da195af976c3ff
ToppCellBiopsy_Control_(H.)-Epithelial-KRT5-/KRT17+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CYP27C1 NRK SSTR2 CDH3 EPHA10

2.46e-051997753b1f56c8b40bb36922a31d2d440a8c468a8aa3f1
ToppCellproximal-Epithelial-Proliferating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAT2 MKI67 ARHGAP11A CDH3 PLK4

2.46e-05199775e8549b2c4152cb23548351d9cee27c3805892cd8
ToppCellproximal-3-Epithelial-Proliferating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAT2 MKI67 ARHGAP11A CDH3 PLK4

2.46e-051997752263bb73d9c5693b44d91d2548305efc1b6e4079
ToppCellBiopsy_Other_PF-Epithelial-Proliferating_Epithelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

FAT2 MKI67 ARHGAP11A PLK4 CNTN2

2.46e-05199775d73667e2e93026d95184e24ff0bc90afd1fb74a9
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 MYO7B ADAMTS16 PCDHAC1

9.37e-051377744dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 MYO7B ADAMTS16 PCDHAC1

9.37e-05137774c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

TNRC18 LAMA5 CDH3 DNMT3B

1.17e-0414577480684ec249fa445c1b35f94608a4a6824d53f2d9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDX1 CYP27C1 SSTR2 BEND2

1.17e-04145774051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

TNRC18 LAMA5 CDH3 DNMT3B

1.17e-04145774cb534333fba44b241b14fb0d7b74e843f4e7f9f8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 NKPD1 ARHGAP11A BEND2

1.51e-04155774969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HOXA7 HOXA9 ABCC11 DNMT3B

1.55e-0415677496747447ba7dc2c10079cee44394b19ce60b2f41
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF24 HMCN1 ADAMTS16 TMEM151A

1.55e-041567744d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM151A NT5DC3 CNTN2 RYR1

1.58e-041577748d30d8e6fae93afcada6bd68799439335cd65b69
ToppCellfacs-Heart-Unknown-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM151A NT5DC3 CNTN2 RYR1

1.58e-041577742ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM151A NT5DC3 CNTN2 RYR1

1.58e-041577748a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP27C1 SGCE SSTR2 ANKRD33B

1.74e-041617740d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 ARHGAP11A PLK4 EPHA10

1.83e-041637743f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellInfluenza_Severe-cDC|World / Disease group and Cell class

HOXA7 EHHADH METTL27 DNMT3B

1.87e-04164774c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRK MKI67 RYR1 LRP8

1.87e-041647745638d95c7cc5e59c4a7bda30268a904a01861a5f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHIA MKI67 ARHGAP11A PLK4

1.92e-04165774eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellInfluenza_Severe-cDC|Influenza_Severe / Disease group and Cell class

HOXA7 EHHADH METTL27 DNMT3B

1.96e-04166774b40bdf0f7f381e25be61188e9f6c294d25a8b824
ToppCell10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

MKI67 ARHGAP11A PLK4 DNMT3B

2.01e-0416777482739226347d74897be000f429b73543a031af96
ToppCell10x5'-Lung-Hematopoietic_progenitors|Lung / Manually curated celltypes from each tissue

MKI67 ARHGAP11A PLK4 DNMT3B

2.01e-04167774dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DLGAP2 PCDHAC1 SSTR2 ANKRD33B

2.01e-041677748b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

STS USP4 STK40 ALG13

2.01e-04167774cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 WDR90 ARHGAP11A LRP8

2.05e-04168774a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellfacs-Heart-LA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA7 CDX1 MYO7B METTL27

2.10e-04169774421fb287c7e439d1870b7950c5e3ca34106e014a
ToppCellfacs-Heart-LA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA7 CDX1 MYO7B METTL27

2.10e-04169774383639ec4f9d0c6255e0881edca15cdd1980a37c
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HOXA9 LAMA5 SGCE CNOT4

2.20e-04171774943fbca8a6ac04052a2a85aca7b21a3461cd96f7
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT2 CYP27C1 CDH3 RYR1

2.25e-04172774e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT2 MKI67 ARHGAP11A RYR1

2.40e-041757749142ed8ca2f1c0c518deb21988221406f62fe38c
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB|TCGA-Thymus / Sample_Type by Project: Shred V9

NRK SGCE TCF7L1 RYR1

2.40e-0417577450f9b994bdd389158f92f891944ea81b2fb15eef
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

STS ADAMTS16 EPHA10 SOAT1

2.45e-041767740923b01137d6f9956ca815b41102c81e82624065
ToppCellClub_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

HMCN1 CYP27C1 LAMA5 CDH3

2.45e-0417677488c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HYAL1 NRK SGCE MAP4K2

2.45e-041767745d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRCP MKI67 ARHGAP11A SOAT1

2.45e-04176774270d7908dbd84028958d257f94941dc685e20255
ToppCellsevere_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

HOXA7 HOXA9 ABCC11 DNMT3B

2.50e-04177774289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO7B EHHADH SLC22A2 ANKRD33B

2.67e-04180774864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

MKI67 WDR90 ARHGAP11A LRP8

2.73e-04181774c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCellIIH-cycling-|IIH / Condition, Cell_class and T cell subcluster

EHHADH MKI67 ARHGAP11A PLK4

2.73e-041817747f4fed9e296bc22cb5a1e6c8e3c4b641e97c3078
ToppCellIIH-cycling|IIH / Condition, Cell_class and T cell subcluster

EHHADH MKI67 ARHGAP11A PLK4

2.73e-04181774ec3e782ce93dcfe1a54fb7284e4e39063614b0e2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DOCK8 ADAMTS16 ANKRD33B

2.78e-041827745e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

DOCK11 EHHADH APMAP ACSS2

2.84e-041837743f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

MYO7B DOCK11 DOCK8 SLC22A2

2.90e-0418477451ed1ebfdef45149541917c66cbacad87072e51f
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA9 LAMA5 TMEM151A CDH3

2.96e-0418577411fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast|bone_marrow / Manually curated celltypes from each tissue

EHHADH WDR90 NT5DC3 PLK4

2.96e-04185774a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B DOCK11 DOCK8 ANKRD33B

3.02e-04186774f28d72b47624b69a580b4429e2be560a26898591
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

ZSCAN32 APMAP SNX33 LRP8

3.02e-04186774701eea0016d69f0f9d29b613948f91239096e6c7
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK11 LAMA5 TMEM151A CDH3

3.09e-041877748e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA7 HOXA9 TCF7L1 SOAT1

3.09e-04187774ab109aa51beae3df474c15002e70361f328cadad
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

MYO7B DOCK8 EHHADH SLC22A2

3.09e-04187774d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DOCK8 SLC22A2 ANKRD33B

3.09e-041877749d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 CYP27C1 NRK ADAMTS16

3.09e-04187774f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

MYO7B EHHADH SLC22A2 ANKRD33B

3.09e-04187774738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellfacs-Large_Intestine-Distal-18m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA7 HOXA9 TCF7L1 SOAT1

3.09e-04187774a4c408fc941d2e8a811a26aa916c0b3e3341163a
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

MYO7B EHHADH SLC22A2 ACSS2

3.09e-04187774acd305475f3609800af0d7bc68d83ef41228080b
ToppCellwk_08-11-Mesenchymal-Mesothelial-Early_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PAK4 LAMA5 TMEM151A LRP8

3.15e-041887746151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HOXA9 MKI67 UROD DNMT3B

3.15e-04188774557a0ac069a6ff4e687cac032f64170b9b247165
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DLGAP2 DOCK11 TMEM151A CDH3

3.15e-041887749655a4c47b644a870017d349b99063e17dbae572
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B EHHADH SLC22A2 ANKRD33B

3.21e-04189774204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B EHHADH SLC22A2 ANKRD33B

3.21e-0418977413fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CYP27C1 NRK ADAMTS16 CNTN2

3.21e-04189774eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN1 CYP27C1 NRK ADAMTS16

3.21e-04189774e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CYP27C1 NRK ADAMTS16 CNTN2

3.21e-0418977440764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LAMA5 TMEM151A CDH3 LRP8

3.34e-041917744c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT2 MKI67 ARHGAP11A RYR1

3.34e-041917740f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 SLC22A2 ADAMTS16 ANKRD33B

3.34e-041917741cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MKI67 ARHGAP11A PLK4 DNMT3B

3.41e-04192774026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT2 CYP27C1 CDH3 RYR1

3.48e-041937747c34abdcb8839b9fb25457a79af6c5e7b9714b21
ToppCellDividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

MKI67 ARHGAP11A PLK4 DNMT3B

3.62e-0419577479ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

DLGAP2 HMCN1 DOCK8 SGCE

3.62e-04195774de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellDividing_cells-Dividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

MKI67 ARHGAP11A PLK4 DNMT3B

3.62e-0419577419829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCell(1)_T_cells-(1)_T_cells_Dividing|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MKI67 ARHGAP11A PLK4 DNMT3B

3.62e-04195774cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAK4 LAMA5 TMEM151A CDH3

3.69e-04196774429de4119c8b2193c992d36a6af84f806730cbee
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FAT2 CYP27C1 LAMA5 CDH3

3.69e-041967743b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAK4 LAMA5 TMEM151A CDH3

3.69e-041967748c8a73d9d9581b8d9a9babfa93459d12fb9eb3ac
ToppCellCaecum-(1)_T_cell-(18)_cycling_gd_T|Caecum / shred on region, Cell_type, and subtype

MKI67 ARHGAP11A PLK4 RYR1

3.83e-0419877464278d8831c81874937e76b561c53928dfc437c5
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT2 MKI67 ARHGAP11A PLK4

3.83e-04198774f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellCaecum-T_cell-cycling_gd_T|Caecum / Region, Cell class and subclass

MKI67 ARHGAP11A PLK4 RYR1

3.83e-041987745b719b67f8384863077070e1eb7e04a320e6dab4
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT2 LAMA5 CDH3 TCF7L1

3.83e-041987745374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellmLN-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

HOXA9 MKI67 ARHGAP11A PLK4

3.90e-04199774c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT2 LAMA5 CDH3 TCF7L1

3.90e-0419977494a7867e800df352731796de8c24cba133c29622
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA9 NRK ADAMTS16 UROD

3.90e-04199774bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCellMS-IIF-Others-HSPC|IIF / Disease, condition lineage and cell class

HOXA7 HOXA9 UROD DNMT3B

3.90e-041997743384db80f6024bcabe2625f24d5f4e0d3d8caa7e
ToppCellPSB-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT2 HMCN1 CDH3 RYR1

3.90e-041997742add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

STS MKI67 ARHGAP11A PLK4

3.90e-041997741d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell(1)_T_cell-(18)_cycling_gd_T|(1)_T_cell / shred on Cell_type and subtype

MKI67 ARHGAP11A PLK4 DNMT3B

3.90e-041997749369d0e4efe809e3e8757294ebebba5a47b30528
Diseaseprostatitis (biomarker_via_orthology)

SMAD4 DNMT3A DNMT3B

3.55e-0612763DOID:14654 (biomarker_via_orthology)
Diseaseendometriosis of uterus (is_marker_for)

DNMT3A DNMT3B

1.96e-053762DOID:288 (is_marker_for)
Diseasecongenital heart disease (biomarker_via_orthology)

DNMT3A DNMT3B

3.92e-054762DOID:1682 (biomarker_via_orthology)
Diseasechronic myeloid leukemia (is_marker_for)

SMAD4 DNMT3A DNMT3B

4.59e-0527763DOID:8552 (is_marker_for)
Disease1,5 anhydroglucitol measurement

PCDHAC1 PCDHA11 SI

5.72e-0529763EFO_0008009
Diseaselung cancer (is_marker_for)

MKI67 DNMT3A DNMT3B

1.40e-0439763DOID:1324 (is_marker_for)
Diseasecolon cancer (biomarker_via_orthology)

MKI67 IKBKB SMAD4

1.40e-0439763DOID:219 (biomarker_via_orthology)
DiseasePR domain zinc finger protein 1 measurement

EHHADH USP4

3.55e-0411762EFO_0801904
Diseaseautoimmune thrombocytopenic purpura (is_marker_for)

DNMT3A DNMT3B

5.01e-0413762DOID:8924 (is_marker_for)
Diseaseprotein C measurement

MYO7B CYP27C1

8.68e-0417762EFO_0004633
Diseasetotal blood protein measurement

DIPK1A SLC22A2 ACSF3 USP4 ANKRD33B TCF7L1

1.07e-03449766EFO_0004536
Diseasehepatocellular carcinoma (is_marker_for)

SNW1 PLK4 SMAD4 DNMT3A DNMT3B

1.09e-03301765DOID:684 (is_marker_for)
Diseasepulmonary hypertension (biomarker_via_orthology)

HYAL1 RYR1 SMAD4

1.17e-0380763DOID:6432 (biomarker_via_orthology)
Diseaseacetate measurement

APMAP ACSS2

1.21e-0320762EFO_0010112
DiseaseInfiltrating duct carcinoma of female breast

NRK EPHA10

1.33e-0321762C3165106
DiseaseSeckel syndrome

PLK4 DNMT3A

1.46e-0322762C0265202
Diseasefat intake measurement

NRAP DNMT3A

1.46e-0322762EFO_0010809
DiseaseDwarfism

PLK4 DNMT3A

1.89e-0325762C0013336
Diseaseendometriosis (is_marker_for)

DNMT3A DNMT3B

1.89e-0325762DOID:289 (is_marker_for)
DiseaseAdenocarcinoma of large intestine

NRK STK40 SMAD4

1.98e-0396763C1319315
Diseasecytotoxicity measurement, response to clozapine

DLGAP2 HMCN1

2.54e-0329762EFO_0006952, GO_0097338

Protein segments in the cluster

PeptideGeneStartEntry
MATPGRPWAQARSAY

FAM246A

1

A0A494C0Y3
MATPGRPWAQARSAY

FAM246B

1

A0A494C0N9
MAEPGRPWAQARSAY

FAM246C

1

P0DSO1
GAQRPTPYEWMRRSV

CDX1

126

P47902
GWQSYTMRQRVSPYP

ERVK13-1

121

Q9NX77
VPAWNAMPSRKGRGY

ALG13

551

Q9NP73
KTSMYAGAIPRWLRP

CYP27C1

266

Q4G0S4
ARYFWGNLPGMNRPL

DNMT3A

791

Q9Y6K1
RARYFWGNLPGMNRP

DNMT3B

731

Q9UBC3
WAQYRPGLGRFMPDN

CHIA

31

Q9BZP6
AQRMSPWPQDSRGLY

DLGAP2

646

Q9P1A6
WMSGGVAVPLYRKHP

ACSF3

116

Q4G176
YWVGMSTIRPNPGFS

APMAP

316

Q9HDC9
PWPGIMRTVYGNHER

ACSS2

521

Q9NR19
GRNPGVAWEYSMPRL

ADAMTS16

846

Q8TE57
PRRGMSPQEWATYTG

ANKRD33B

221

A6NCL7
MRPFAQHPWRGFASG

PARP9

836

Q8IXQ6
AKRRSFIGTPYWMAP

MAP4K2

166

Q12851
TPVWCMRQAGRYLPE

UROD

31

P06132
PNPDWRYSASLRAGM

PCDHA11

801

Q9Y5I1
GQMYSPREMRANGSW

PBX2

391

P40425
LMWHPRQRGTDPTYG

IKBKB

281

O14920
GWTPPGSYKVEMARR

NRAP

1666

Q86VF7
SYFGRPWRNIRMPCS

BEND2

661

Q8NDZ0
WPRHKGGPMFYASTV

EHHADH

656

Q08426
GGAMVWPPTYSRNER

FAT2

4176

Q9NYQ8
AAPDGRYMRSWLEPT

HOXA9

101

P31269
MTRKRTYWVPNSSGG

ABCC11

1

Q96J66
RPRPSWITTMYGGKN

PRCP

401

P42785
DPANYGTGMERWPRT

MKI67

2051

P46013
YTTMSGRSPALWAAP

EPHA10

801

Q5JZY3
FSWRGYAQMAPVQPR

LAMA5

901

O15230
TRGLPMPAITWYKDG

HMCN1

1571

Q96RW7
RWYPASLPRMASSPA

METTL27

216

Q8N6F8
MPRQPNPDWRYSASL

PCDHAC1

811

Q9H158
GQYRMPFAWAARPIF

DOCK11

521

Q5JSL3
CQRLGKYRMPFAWAP

DOCK8

391

Q8NF50
SPADLHGMWYPTVRR

COG3

546

Q96JB2
PAIRQATRWKYTPMG

C19orf71

41

A6NCJ1
ATRWKYTPMGRDAAG

C19orf71

46

A6NCJ1
AVPVYRGSPSVRDWM

FUT11

301

Q495W5
KMLRATAPCWFRPGY

REXO1L1P

46

Q8IX06
CRARASPPATYRWKM

CNTN2

61

Q02246
AGESMFTRYLWPAPR

MAN2B2

381

Q9Y2E5
WGQSRALYPSIYMPA

HYAL1

236

Q12794
MARSLCPGAWLRKPY

DIPK1A

1

Q5T7M9
IGRRYPWAASNMVAG

SLC22A2

401

O15244
SPSLRWQMALYRGVP

RYR1

3566

P21817
APNSPAWRATYLIMG

CDH3

356

P22223
NFRIYPWMRSSGPDR

HOXA7

116

P31268
WLGPDMKRCYRAPQS

LRP8

726

Q14114
RRKSLVGTPYWMAPE

PAK4

471

O96013
QSLRPMPQRYGDVFW

INCA1

31

Q0VD86
HYWITRGFQMQGPPR

MMP20

366

O60882
NGRRNSFIGTPYWMA

NRK

206

Q7Z2Y5
RLVGTNYRMSWTGPN

ARHGAP11A

511

Q6P4F7
SSPYQEFLWRMQRPG

ERVW-1

31

Q9UQF0
SYPRNPTVRWGYVAM

SOAT1

311

P35610
SGRPYRGKPSDMWAL

STK40

246

Q8N2I9
MISSGSWRDRPFKPY

FARSA

196

Q9Y285
YREMTRKPWLPGDAG

NKPD1

331

Q17RQ9
APGTAPDMKRYLWER

NT5DC3

46

Q86UY8
LRMSFVKGWGPDYPR

SMAD4

501

Q13485
TYSIEMGPRGPQWKA

SNX33

211

Q8WV41
RYPVRSGMASWSRTG

STS

86

P08842
WGMFTRDQPPGYKLN

SI

1131

P14410
MVFADPRSPPWYARA

TMEM151A

271

Q8N4L1
SKTRGMEPPWGYQNR

PLK4

571

O00444
PIMIYAGLRSNQWGR

SSTR2

176

P30874
TFNTNLMGYPDRPGW

SGCE

86

O43556
FPGQAARYPWMAFPR

CNOT4

491

O95628
GSASPSRYHGPARWM

ATG4D

181

Q86TL0
KWPMRSRLYIGATGQ

TCF24

131

Q7RTU0
PRSGNASMWLAGHPY

TNRC18

806

O15417
GRPNLPYIGRIQSMW

TNRC18

2831

O15417
YSGNGRANMVWRPDT

WDR90

1116

Q96KV7
GPLMRTTLQRGAQWY

USP4

21

Q13107
MYNPWQVGASLAPAR

nan

1

P0C879
WMCPGPAQRALYRGA

ZSCAN32

226

Q9NX65
FSRGWSRDQPGQAPM

RALGAPA1

716

Q6GYQ0
SPGGARTYLQMKWPL

TCF7L1

141

Q9HCS4
AWRGGKDMAQSIYRP

SNW1

436

Q13573
PLASMVGGRAKNLWY

PIGO

656

Q8TEQ8
RYMGDYPSRQAWPTL

MYO7B

1676

Q6PIF6