Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH5 DNAH7	5.40e-05	18	83	3	GO:0008569
GeneOntologyMolecularFunction	microtubule motor activity	DNHD1 DNAH5 DNAH7 KIF11	2.07e-04	70	83	4	GO:0003777
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DNAH5 DNAH7	2.10e-04	28	83	3	GO:0051959
GeneOntologyMolecularFunction	methylated histone binding	ZZZ3 SPIN2A SPIN2B TRIM24	4.55e-04	86	83	4	GO:0035064
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH5 DNAH7	4.86e-04	37	83	3	GO:0045505
GeneOntologyMolecularFunction	methylation-dependent protein binding	ZZZ3 SPIN2A SPIN2B TRIM24	4.96e-04	88	83	4	GO:0140034
GeneOntologyCellularComponent	axonemal dynein complex	DNHD1 DNAH5 DNAH7	1.40e-04	25	85	3	GO:0005858
HumanPheno	Absent radius	FANCD2 TRIO CHN1 FANCA	1.79e-05	27	31	4	HP:0003974
HumanPheno	Absent forearm bone	FANCD2 TRIO CHN1 FANCA	2.08e-05	28	31	4	HP:0003953
HumanPheno	Aplasia involving forearm bones	FANCD2 TRIO CHN1 FANCA	2.08e-05	28	31	4	HP:0009822
Domain	TF_fork_head_CS_2	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	4.84e-08	46	82	6	IPR030456
Domain	TF_fork_head_CS_1	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	5.53e-08	47	82	6	IPR018122
Domain	FH	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	7.15e-08	49	82	6	SM00339
Domain	FORK_HEAD_1	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	7.15e-08	49	82	6	PS00657
Domain	FORK_HEAD_2	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	7.15e-08	49	82	6	PS00658
Domain	Fork_head_dom	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	7.15e-08	49	82	6	IPR001766
Domain	FORK_HEAD_3	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	7.15e-08	49	82	6	PS50039
Domain	Forkhead	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	7.15e-08	49	82	6	PF00250
Domain	SPIN-2	SPIN2A SPIN2B	1.90e-05	2	82	2	IPR029564
Domain	Dynein_HC_stalk	DNHD1 DNAH5 DNAH7	2.87e-05	14	82	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH5 DNAH7	2.87e-05	14	82	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH5 DNAH7	2.87e-05	14	82	3	PF08393
Domain	MT	DNHD1 DNAH5 DNAH7	2.87e-05	14	82	3	PF12777
Domain	DHC_fam	DNHD1 DNAH5 DNAH7	3.57e-05	15	82	3	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DNAH5 DNAH7	3.57e-05	15	82	3	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH5 DNAH7	3.57e-05	15	82	3	PF03028
Domain	WHTH_DNA-bd_dom	FOXD2 FOXN1 KAT5 FOXH1 FOXD1 FOXL1 FOXE3	9.36e-05	242	82	7	IPR011991
Domain	Spin-Ssty	SPIN2A SPIN2B	1.89e-04	5	82	2	PF02513
Domain	SPIN/Ssty	SPIN2A SPIN2B	1.89e-04	5	82	2	IPR003671
Domain	TLV_coat	ERVV-2 ERVV-1	3.94e-04	7	82	2	PF00429
Domain	-	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	3.95e-04	218	82	6	1.10.10.10
Domain	TLV/ENV_coat_polyprotein	ERVV-2 ERVV-1	5.24e-04	8	82	2	IPR018154
Domain	Dynein_heavy_chain_D4_dom	DNAH5 DNAH7	1.67e-03	14	82	2	IPR024317
Domain	AAA_8	DNAH5 DNAH7	1.67e-03	14	82	2	PF12780
Domain	Cation_ATPase_N	ATP13A2 ATP4A	2.78e-03	18	82	2	SM00831
Domain	ZF_DAG_PE_1	TNS2 DGKE CHN1	2.80e-03	64	82	3	PS00479
Domain	ZF_DAG_PE_2	TNS2 DGKE CHN1	2.80e-03	64	82	3	PS50081
Domain	C1	TNS2 DGKE CHN1	2.93e-03	65	82	3	SM00109
Domain	PE/DAG-bd	TNS2 DGKE CHN1	3.06e-03	66	82	3	IPR002219
Domain	ATPase_P-typ_cation-transptr_N	ATP13A2 ATP4A	3.10e-03	19	82	2	IPR004014
Domain	Znf_FYVE_PHD	TAF3 ZBTB4 RIMS2 TRIM24	4.01e-03	147	82	4	IPR011011
Domain	HAD-like_dom	LPIN2 ATP13A2 ATP4A	5.07e-03	79	82	3	IPR023214
Domain	-	ATP13A2 ATP4A	8.67e-03	32	82	2	3.40.1110.10
Domain	-	ATP13A2 ATP4A	8.67e-03	32	82	2	2.70.150.10
Pathway	REACTOME_KERATAN_SULFATE_DEGRADATION	GLB1L3 PRELP OGN	3.22e-05	15	60	3	M691
Pathway	REACTOME_KERATAN_SULFATE_DEGRADATION	GLB1L3 PRELP OGN	3.22e-05	15	60	3	MM14799
Pubmed	Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.	ERVV-2 ERVV-1	6.04e-06	2	86	2	18826608
Pubmed	PIK3R6 Promotes Angiogenesis in Hepatocellular carcinoma by Activating STAT3 Signaling Pathway.	PIK3R6 STAT3	6.04e-06	2	86	2	37708538
Pubmed	Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration.	STAT3 FOXD1	6.04e-06	2	86	2	35263586
Pubmed	Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.	ERVV-2 ERVV-1	6.04e-06	2	86	2	23555306
Pubmed	KLF3 is a crucial regulator of metastasis by controlling STAT3 expression in lung cancer.	KLF3 STAT3	6.04e-06	2	86	2	31486564
Pubmed	Perivascular CD73+ cells attenuate inflammation and interstitial fibrosis in the kidney microenvironment.	NT5E FOXD1	6.04e-06	2	86	2	31364375
Pubmed	A FANCD2 domain activates Tip60-dependent apoptosis.	FANCD2 KAT5	6.04e-06	2	86	2	20507282
Pubmed	Inhibition of O-GlcNAcase Inhibits Hematopoietic and Leukemic Stem Cell Self-Renewal and Drives Dendritic Cell Differentiation via STAT3/5 Signaling.	OGA STAT3	6.04e-06	2	86	2	36124999
Pubmed	Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression.	SPIN2A SPIN2B	6.04e-06	2	86	2	12145692
Pubmed	Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair.	FANCD2 FANCA	6.04e-06	2	86	2	15650050
Pubmed	TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma.	TRIM24 STAT3	1.81e-05	3	86	2	29129908
Pubmed	Proximal Tubule CD73 Is Critical in Renal Ischemia-Reperfusion Injury Protection.	NT5E FOXD1	1.81e-05	3	86	2	27628903
Pubmed	Tip60 is a co-repressor for STAT3.	KAT5 STAT3	1.81e-05	3	86	2	12551922
Pubmed	CD4+CD25+ regulatory T cells inhibit the antigen-dependent expansion of self-reactive T cells in vivo.	FOXN1 ATP4A	1.81e-05	3	86	2	16424190
Pubmed	The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.	FANCD2 FANCA	1.81e-05	3	86	2	26584049
Pubmed	Overexpression of Desmoglein 2 in a Mouse Model of Gorlin Syndrome Enhances Spontaneous Basal Cell Carcinoma Formation through STAT3-Mediated Gli1 Expression.	DSG2 STAT3	1.81e-05	3	86	2	30291846
Pubmed	The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.	FOXN1 STAT3	1.81e-05	3	86	2	27875549
Pubmed	Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1.	MAP3K5 FANCA	1.81e-05	3	86	2	16109778
Pubmed	TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells.	KAT5 TRIM24	3.61e-05	4	86	2	19909775
Pubmed	Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.	FANCD2 FANCA	3.61e-05	4	86	2	22922648
Pubmed	Tip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathway.	FANCD2 KAT5	3.61e-05	4	86	2	18263878
Pubmed	CXCR4 induction in hematopoietic progenitor cells from Fanca(-/-), -c(-/-), and -d2(-/-) mice.	FANCD2 FANCA	3.61e-05	4	86	2	18279715
Pubmed	Prevention of autoimmune gastritis in mice requires extra-thymic T-cell deletion and suppression by regulatory T cells.	FOXN1 ATP4A	3.61e-05	4	86	2	17603058
Pubmed	Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells.	FOXN1 STAT3	3.61e-05	4	86	2	26789017
Pubmed	Gene knockouts that cause female infertility: search for novel contraceptive targets.	ACVR2A STAT3 FANCA	4.57e-05	28	86	3	15970507
Pubmed	Multimodal Hox5 activity generates motor neuron diversity.	KLF3 PCDH10 STAT3	5.09e-05	29	86	3	39289460
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXN1 KAT5 BMS1 FOXH1 TRIM24 STAT3 CYFIP2 FOXD1 FOXL1 NUP205	5.12e-05	857	86	10	25609649
Pubmed	Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development.	FANCD2 FANCA	6.01e-05	5	86	2	37580626
Pubmed	Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis.	FOXD2 FOXD1	6.01e-05	5	86	2	9510020
Pubmed	Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.	FOXN1 STAT3	6.01e-05	5	86	2	26255562
Pubmed	Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.	FANCD2 FANCA	6.01e-05	5	86	2	26980189
Pubmed	The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly.	FANCD2 FANCA	6.01e-05	5	86	2	16474167
Pubmed	Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability.	FANCD2 KAT5	6.01e-05	5	86	2	29760279
Pubmed	Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression.	NT5E STAT3	6.01e-05	5	86	2	22406269
Pubmed	Deletion of Fanca or Fancd2 dysregulates Treg in mice.	FANCD2 FANCA	6.01e-05	5	86	2	24501220
Pubmed	Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.	FOXN1 STAT3	6.01e-05	5	86	2	15292206
Pubmed	Fanconi Anemia Mesenchymal Stromal Cells-Derived Glycerophospholipids Skew Hematopoietic Stem Cell Differentiation Through Toll-Like Receptor Signaling.	FANCD2 FANCA	6.01e-05	5	86	2	26212365
Pubmed	Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction.	PCDH10 CYFIP2	6.01e-05	5	86	2	18644894
Pubmed	Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12).	FOXD1 FOXE3	9.01e-05	6	86	2	8825632
Pubmed	Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses.	FANCD2 FANCA	9.01e-05	6	86	2	24966277
Pubmed	FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3.	FANCD2 FANCA	9.01e-05	6	86	2	18212739
Pubmed	FANCE: the link between Fanconi anaemia complex assembly and activity.	FANCD2 FANCA	9.01e-05	6	86	2	12093742
Pubmed	Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.	ERVV-2 ERVV-1	9.01e-05	6	86	2	23085571
Pubmed	Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance.	FANCD2 FANCA	9.01e-05	6	86	2	20450923
Pubmed	A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1.	SPIN2A SPIN2B	9.01e-05	6	86	2	29061846
Pubmed	Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems.	FANCD2 FANCA	9.01e-05	6	86	2	12649160
Pubmed	A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.	FOXN1 STAT3	1.26e-04	7	86	2	23948297
Pubmed	Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia.	FANCD2 FANCA	1.26e-04	7	86	2	12913077
Pubmed	The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.	FANCD2 FANCA	1.26e-04	7	86	2	24451376
Pubmed	Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development.	TULP4 RIMS2	1.68e-04	8	86	2	39117691
Pubmed	DNA polymerase POLN participates in cross-link repair and homologous recombination.	FANCD2 FANCA	1.68e-04	8	86	2	19995904
Pubmed	X-linked inheritance of Fanconi anemia complementation group B.	FANCD2 FANCA	1.68e-04	8	86	2	15502827
Pubmed	Syncytins expressed in human placental trophoblast.	ERVV-2 ERVV-1	1.68e-04	8	86	2	33504453
Pubmed	Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.	FANCD2 FANCA	1.68e-04	8	86	2	29323295
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	KAT5 BMS1 ZDBF2 OGA TRIM24 TASOR	2.00e-04	339	86	6	30415952
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD2 FOXD1	2.15e-04	9	86	2	12412011
Pubmed	Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1.	FANCD2 FANCA	2.15e-04	9	86	2	23303816
Pubmed	Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.	MKLN1 XPR1	2.15e-04	9	86	2	23829686
Pubmed	Interaction network of human early embryonic transcription factors.	TAF3 ZZZ3 KAT5 ACACB KLF3 TRIM24	2.41e-04	351	86	6	38297188
Pubmed	Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2.	FOXD2 FOXD1	2.68e-04	10	86	2	26071365
Pubmed	Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.	FOXD2 FOXD1	3.28e-04	11	86	2	7683413
Pubmed	Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response.	FANCD2 FANCA	3.28e-04	11	86	2	26625197
Pubmed	Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.	FANCD2 PVR	3.28e-04	11	86	2	24755620
Pubmed	Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis.	FOXD1 FOXL1	3.28e-04	11	86	2	28506991
Pubmed	The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.	FANCD2 FANCA	3.28e-04	11	86	2	19965384
Pubmed	Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy.	PRELP OGN	3.28e-04	11	86	2	12796502
Pubmed	A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.	FANCD2 FANCA	3.93e-04	12	86	2	16116422
Pubmed	A novel ubiquitin ligase is deficient in Fanconi anemia.	FANCD2 FANCA	3.93e-04	12	86	2	12973351
Pubmed	The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development.	KAT5 GPT2	4.63e-04	13	86	2	37024457
Pubmed	Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway.	FANCD2 FANCA	4.63e-04	13	86	2	27986371
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD1 FOXL1	4.63e-04	13	86	2	7957066
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	FANCD2 DSG2 PVR DGKE QKI OGA KIF11 NUP205 FANCA	5.39e-04	942	86	9	31073040
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH5 DNAH7	5.39e-04	14	86	2	9373155
Pubmed	Cilia-dependent GLI processing in neural crest cells is required for tongue development.	FOXD2 FOXD1	5.39e-04	14	86	2	28286175
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZZZ3 ACACB ZDBF2 TRIM24 TASOR KIF11	6.08e-04	418	86	6	34709266
Pubmed	Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.	KAT5 STAT3	6.21e-04	15	86	2	17255939
Pubmed	Esophageal Atresia / Tracheoesophageal Fistula Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	FANCD2 FANCA	7.09e-04	16	86	2	20301753
Pubmed	Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.	FANCD2 FANCA	7.09e-04	16	86	2	27760317
Pubmed	Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair.	FANCD2 FANCA	7.09e-04	16	86	2	31980815
Pubmed	Human transcription factor protein interaction networks.	TAF3 ZZZ3 KAT5 ACACB BMS1 KLF3 QKI TRIM24 STAT3 FOXL1 NUP205	7.86e-04	1429	86	11	35140242
Pubmed	Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity.	FOXN1 DSG2	8.02e-04	17	86	2	18692037
Pubmed	MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.	PCDH10 NOS1	8.02e-04	17	86	2	27779093
Pubmed	ISL1/SHH/CXCL12 signaling regulates myogenic cell migration during mouse tongue development.	FOXD2 FOXD1	8.02e-04	17	86	2	36196625
Pubmed	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	LPIN2 KIF11	8.02e-04	17	86	2	21490949
Pubmed	Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia.	FOXD2 FOXD1	1.01e-03	19	86	2	15107405
Pubmed	Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development.	NDST2 FOXD1	1.12e-03	20	86	2	17107998
Pubmed	T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.	KAT5 TRIM24	1.12e-03	20	86	2	11877444
Pubmed	A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.	FANCD2 FANCA	1.12e-03	20	86	2	22705371
Pubmed	Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.	FANCD2 POLA2 FANCA	1.20e-03	84	86	3	19237606
Pubmed	Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins.	CHN1 ATP13A2	1.23e-03	21	86	2	23284715
Pubmed	Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.	FANCD2 STAT3 KIF11	1.33e-03	87	86	3	33798452
Pubmed	Gain-of-Function MN1 Truncation Variants Cause a Recognizable Syndrome with Craniofacial and Brain Abnormalities.	SPIN2B KIF11	1.35e-03	22	86	2	31839203
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	TULP4 FOXH1 RIMS2 OGN FANCA	1.37e-03	329	86	5	17474147
Pubmed	A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.	FBXO36 CHN1 PSKH2 NUP205 FANCA	1.41e-03	331	86	5	19490893
Pubmed	Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.	OGN KIF11 FOXD1	1.47e-03	90	86	3	28535371
Pubmed	A quantitative protein interaction network for the ErbB receptors using protein microarrays.	TNS2 CHN1 STAT3	1.47e-03	90	86	3	16273093
Pubmed	Fanconi Anemia	FANCD2 FANCA	1.48e-03	23	86	2	20301575
Pubmed	Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity.	PCDH10 NOS1	1.48e-03	23	86	2	24351932
Pubmed	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	AHI1 PVR STAT3	1.52e-03	91	86	3	21833088
Pubmed	ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.	AHI1 PGM2L1 CYFIP2 MAP3K5	1.62e-03	202	86	4	33601422
Cytoband	Xp11.1	SPIN2A SPIN2B	2.08e-05	4	86	2	Xp11.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1p33	FOXD2 CYP4B1 FOXE3	2.11e-04	61	86	3	chr1p33
Cytoband	5p15.2	TRIO DNAH5	1.18e-03	27	86	2	5p15.2
Cytoband	1q44	OR14K1 OR14A2 OR14I1	1.19e-03	110	86	3	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr6q23	AHI1 TAAR2 MAP3K5	1.49e-03	119	86	3	chr6q23
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR14K1 OR14A2 OR14I1	1.83e-03	128	86	3	chr1q44
GeneFamily	Olfactory receptors, family 14	OR14K1 OR14A2 OR14J1 OR14I1	3.55e-09	7	59	4	163
GeneFamily	Forkhead boxes	FOXD2 FOXN1 FOXH1 FOXD1 FOXL1 FOXE3	5.16e-09	43	59	6	508
GeneFamily	Tudor domain containing\|Spindlin family	SPIN2A SPIN2B	1.04e-04	5	59	2	1089
GeneFamily	Small leucine rich repeat proteoglycans	PRELP OGN	6.77e-04	12	59	2	573
GeneFamily	Dyneins, axonemal	DNAH5 DNAH7	1.38e-03	17	59	2	536
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	FANCD2 FANCA	1.92e-03	20	59	2	548
GeneFamily	SH2 domain containing	TNS2 CHN1 STAT3	4.39e-03	101	59	3	741
GeneFamily	Tudor domain containing	SPIN2A SPIN2B	6.48e-03	37	59	2	780
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	TAF3 AHI1 TRIO ZDBF2 RIMS2 QKI OGA TRIM24 TASOR ZNF654 CYFIP2	1.56e-05	595	81	11	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
Drug	Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	AHI1 TRIO PVR KLF3 DGKE QKI OGA	5.97e-06	194	81	7	3280_DN
Drug	lithium indium	SPIN2A SPIN2B	1.25e-05	2	81	2	CID011116062
Drug	scandium phosphate	SPIN2A SPIN2B	1.25e-05	2	81	2	CID006365269
Drug	rubidium nitrate	SPIN2A SPIN2B	1.25e-05	2	81	2	CID000025731
Disease	response to bevacizumab, Proteinuria	TRIO DNAH5	7.59e-05	5	82	2	EFO_0005943, HP_0000093
Disease	Leukemia, Myelocytic, Acute	FANCD2 TRIO PVR STAT3 FANCA	1.24e-04	173	82	5	C0023467
Disease	Cerebellar Diseases	AHI1 NOS1	1.59e-04	7	82	2	C0007760
Disease	chemotherapy-induced alopecia, methylcobalamin deficiency type cblE	TRIO DNAH5	2.11e-04	8	82	2	EFO_0005400, MONDO_0009354
Disease	Fanconi anemia (is_implicated_in)	FANCD2 FANCA	3.38e-04	10	82	2	DOID:13636 (is_implicated_in)
Disease	leukemia	FANCD2 STAT3 FANCA	4.89e-04	55	82	3	C0023418
Disease	skin melanoma (is_marker_for)	FANCD2 STAT3	5.83e-04	13	82	2	DOID:8923 (is_marker_for)
Disease	Fanconi anemia	FANCD2 FANCA	6.79e-04	14	82	2	cv:C0015625
Disease	Bone marrow hypocellularity	FANCD2 FANCA	1.13e-03	18	82	2	C1855710
Disease	selenium measurement, response to dietary selenium supplementation	TRIO DNAH5	1.40e-03	20	82	2	EFO_0006331, EFO_0600021
Disease	Parkinson Disease	ATP13A2 NOS1 MAP3K5	1.73e-03	85	82	3	C0030567
Disease	free cholesterol:total lipids ratio, intermediate density lipoprotein measurement	KAT5 ACACB ATP4A	1.79e-03	86	82	3	EFO_0008595, EFO_0020945
Disease	Fanconi Anemia	FANCD2 FANCA	2.20e-03	25	82	2	C0015625
Disease	Pancytopenia	FANCD2 FANCA	2.37e-03	26	82	2	C0030312
Disease	Acute monocytic leukemia	FANCD2 FANCA	2.37e-03	26	82	2	C0023465
Disease	ergothioneine measurement	RIMS2 DNAH5	2.37e-03	26	82	2	EFO_0021163
Disease	childhood onset asthma	C6orf89 MKLN1 KLF3 KIF11 XPR1	2.41e-03	334	82	5	MONDO_0005405
Disease	Fever	NOS1 STAT3	2.56e-03	27	82	2	C0015967

Protein segments in the cluster

Peptide	Gene	Start	Entry
YQIPKSANLISIPIY	C2orf16	141	Q68DN1
IPIPQYPLYSAVISE	GPT2	211	Q8TD30
LQLYYPPTKPRSPLS	AHI1	496	Q8N157
TSNPVTPKPPYYNIL	ACVR2A	126	P27037
TPKPPYYNILLYSLV	ACVR2A	131	P27037
PKITYSTPPVANLYT	ERVV-2	271	B6SEH9
PYVIYRLNITLPPTS	ALG10B	421	Q5I7T1
KPAYETQLPSLPYLS	DNHD1	3651	Q96M86
FPPLLIPTSKYLINN	MT-ATP6	26	P00846
IPAFYNPVTSLLKPV	BMS1	1106	Q14692
PYTLAPATSILEYPI	QKI	291	Q96PU8
NPLVKPPYSYIALIT	FOXD1	121	Q16676
TPQPPLLKALYTYES	NUP205	1541	Q92621
KQPILIYIPPYAELR	ACACB	2186	O00763
VSLEPAYPPVFYLNK	DSG2	201	Q14126
PNKYGVIYSTPLPEK	KLF3	31	P57682
PEYIAPEVLLRKPYT	PSKH2	226	Q96QS6
TPPKSPVYLDLAYLP	MAP1S	941	Q66K74
QLPTSYLPIYTPNVV	FOXH1	276	O75593
KAVYPPVRPSLYLPL	GLB1L3	406	Q8NCI6
IPTGTTPQRKSYLYP	KIF11	921	P52732
YFSPYPQELTTLPVL	KAT5	246	Q92993
IPHSYYPLKPEIILQ	FSIP2	4101	Q5CZC0
PKITYSTPPVANLYT	ERVV-1	271	B6SEH8
PLGYPIYVSPLTTSL	PCNX3	1776	Q9H6A9
VTPAFPNLQYVLKPS	FAT2	386	Q9NYQ8
YTVIPPTLNPVIYSL	OR14J1	276	Q9UGF5
YSVAPPTLNPVIYCL	OR14K1	276	Q8NGZ2
YVPTPFVPYAVQKLK	PGM2L1	151	Q6PCE3
GPPPSKDYYQLLVTR	FBXO36	16	Q8NEA4
IDAVPPLPKESAYLY	OGN	111	P20774
YLNTVIPYEKKASPP	FEZ1	341	Q99689
QPDSLPYPQYLAVIK	MED29	151	Q9NX70
NLYLLLPPTMNPIVY	OR52N2	281	Q8NGI0
LLTNTRAPYKPPYLT	PCDH10	1021	Q9P2E7
IIPYPPSNRYETLLK	CYFIP2	761	Q96F07
LQGKYPDLPVVLYTS	MFSD4B	376	Q5TF39
YYLDITTPPTPLQLQ	NOS1	1101	P29475
PGSKTLPAPYVKVYL	RIMS2	1286	Q9UQ26
YGPNVISIPVKSYPQ	ATP13A2	216	Q9NQ11
PPLVPGKYRSLLTDY	FANCA	496	O15360
SYIEYTKTLPLTPAP	DNAH7	3691	Q8WXX0
KKYPVVAIPCPITYL	SPINK7	36	P58062
TPQKPPYSYIALIAM	FOXL1	46	Q12952
LYPPVPQVYRQLSKP	CYP4B1	376	P13584
SYPNPYTSISPKIIR	CCDC168	2771	Q8NDH2
PPIKALQLCTLLPYY	DGKE	256	P52429
PIPLITYDAYPKFIE	CHN1	351	P15882
PPPQYPLLIVVYKVL	C6orf89	51	Q6UWU4
LTKNIPELTPYLIYI	ATP4A	791	P20648
PELTPYLIYITVSVP	ATP4A	796	P20648
YSYLSPLQIQQIPIP	METTL4	301	Q8N3J2
RLYITTKLPNPAYTP	DNAH5	3691	Q8TE73
LEKYLAVTPDYVPPL	FANCD2	826	Q9BXW9
AYGPIITVYLQPTPN	OR10D3	251	Q8NH80
LPIYTAPPLQSKYVE	APOOL	41	Q6UXV4
ITAYFVYLKPPSNSP	OR14A2	251	Q96R54
YTVLPPFLNPIIYSL	OR14I1	276	A6ND48
TVFYPSPYPIRSLIK	PARL	86	Q9H300
TRSPLVKPPYSYIAL	FOXD2	121	O60548
VLILEPTKIYQPSYL	MAP3K5	561	Q99683
AVPPYVKLGLTVVYT	GPR137B	36	O60478
PQLLTVNLTVYYPPE	PVR	231	P15151
KEYIPDYLPPIVSSQ	TAF3	121	Q5VWG9
PPLTPTSKVYTIRPY	OGA	706	O60502
SNYPPQYLILKLERP	MKLN1	51	Q9UL63
QPLFPKPIYSYSILI	FOXN1	266	O15353
LSLQLYYIPVLAPEK	PIK3R6	451	Q5UE93
YYIPVLAPEKPAASR	PIK3R6	456	Q5UE93
PLQRGKPPYSYIALI	FOXE3	66	Q13461
VPINPSLYLVKYDGI	SPIN2A	76	Q99865
KVPVIPPRIHYLYLQ	PRELP	96	P51888
ATKLYEGVPLPFYQP	POLA2	316	Q14181
KSFAPPYALQPELYL	SPATA1	121	Q5VX52
IPPALFYKETYLGPN	TASOR	406	Q9UK61
ASQISGLYLPYKVLP	NT5E	151	P21589
FAPISVIPTYVYPLA	XPR1	336	Q9UBH6
VLQPLYPPSLSYCTL	TULP4	1226	Q9NRJ4
DPVPLTVPDYYKIIK	TRIM24	926	O15164
LVSPLVYLYPDIPKE	STAT3	666	P40763
VPINPSLYLVKYDGI	SPIN2B	76	Q9BPZ2
DYYEPLIKQIVISPP	ZDBF2	2051	Q9HCK1
LILTKPYVRPLPPSY	ZNF654	1041	Q8IZM8
SYVYPPVQEFPLALI	ZBTB4	866	Q9P1Z0
YYVSTSPKAKEPLPL	NDST2	36	P52849
CYPLLYSTKITIPVI	TAAR2	146	Q9P1P5
IPVPGRTPNLYIYSK	ZZZ3	711	Q8IYH5
PPYPQSRKLSYEIPT	TNS2	836	Q63HR2
SVKLLNPNYIYDVPP	TRIO	2671	O75962
YEKLPAYLATSPIPT	LPIN2	96	Q92539
YPKVQETLPVTYKPT	MXRA5	1306	Q9NR99