Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	folic acid binding	TYMS MTERF1 SLC19A1	6.72e-05	20	80	3	GO:0005542
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	ANO9 CLCNKA CLCNKB SLC19A1 ANO8	3.53e-04	151	80	5	GO:0008509
GeneOntologyMolecularFunction	chloride channel activity	ANO9 CLCNKA CLCNKB ANO8	3.95e-04	86	80	4	GO:0005254
GeneOntologyMolecularFunction	actin binding	EPS8 DST MYO10 SYNE1 MACF1 VPS16 DMD UTRN	6.61e-04	479	80	8	GO:0003779
GeneOntologyMolecularFunction	integrin binding	PTPN2 DST ADAM23 DMD UTRN	6.90e-04	175	80	5	GO:0005178
GeneOntologyMolecularFunction	protein-glutamic acid ligase activity	TTLL2 TTLL4	6.99e-04	10	80	2	GO:0070739
GeneOntologyMolecularFunction	tubulin-glutamic acid ligase activity	TTLL2 TTLL4	6.99e-04	10	80	2	GO:0070740
GeneOntologyMolecularFunction	monoatomic anion channel activity	ANO9 CLCNKA CLCNKB ANO8	7.82e-04	103	80	4	GO:0005253
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCNKA CLCNKB	8.52e-04	11	80	2	GO:0005247
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	MYO10 GAB4 DAPP1	9.99e-04	49	80	3	GO:0005547
GeneOntologyMolecularFunction	vinculin binding	DMD UTRN	1.20e-03	13	80	2	GO:0017166
GeneOntologyMolecularFunction	ligase activity, forming carbon-nitrogen bonds	MTERF1 TTLL2 TTLL4	1.26e-03	53	80	3	GO:0016879
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	ANO9 CLCNKA CLCNKB ANO8	1.60e-03	125	80	4	GO:0015108
GeneOntologyCellularComponent	filopodium membrane	MYO10 DMD UTRN	6.33e-05	21	78	3	GO:0031527
GeneOntologyCellularComponent	apicolateral plasma membrane	RASGRF1 SLC28A2 MTCL1	1.53e-04	28	78	3	GO:0016327
GeneOntologyCellularComponent	cell projection membrane	EPS8 MYO10 SLC19A1 ARL13B SLC28A2 MACF1 DMD UTRN	2.03e-04	431	78	8	GO:0031253
GeneOntologyCellularComponent	cell leading edge	EPS8 DST PDGFRB MYO10 MACF1 DMD CIT TIAM2	5.48e-04	500	78	8	GO:0031252
MousePheno	abnormal neuromuscular synapse morphology	DST SYNE1 PEX10 DMD UTRN	5.30e-05	95	60	5	MP:0001053
MousePheno	abnormal somatic motor system morphology	DST SYNE1 PEX10 DMD UTRN	6.15e-05	98	60	5	MP:0001051
Domain	Spectrin_repeat	DST TRIO DSP SYNE1 MACF1 DMD UTRN	3.20e-11	29	81	7	IPR002017
Domain	Spectrin/alpha-actinin	DST TRIO DSP SYNE1 MACF1 DMD UTRN	6.83e-11	32	81	7	IPR018159
Domain	SPEC	DST TRIO DSP SYNE1 MACF1 DMD UTRN	6.83e-11	32	81	7	SM00150
Domain	Spectrin	DST TRIO SYNE1 MACF1 DMD UTRN	5.24e-10	23	81	6	PF00435
Domain	IQ	IQCF2 LRRIQ1 RASGRF1 MYO10 IQCF1 CAMTA2 IQCG	2.36e-08	71	81	7	PF00612
Domain	Actinin_actin-bd_CS	DST SYNE1 MACF1 DMD UTRN	4.28e-08	23	81	5	IPR001589
Domain	ACTININ_2	DST SYNE1 MACF1 DMD UTRN	4.28e-08	23	81	5	PS00020
Domain	ACTININ_1	DST SYNE1 MACF1 DMD UTRN	4.28e-08	23	81	5	PS00019
Domain	IQ	IQCF2 LRRIQ1 RASGRF1 MYO10 IQCF1 CAMTA2 IQCG	5.95e-08	81	81	7	SM00015
Domain	IQ_motif_EF-hand-BS	IQCF2 LRRIQ1 RASGRF1 MYO10 IQCF1 CAMTA2 IQCG	1.24e-07	90	81	7	IPR000048
Domain	IQ	IQCF2 LRRIQ1 RASGRF1 MYO10 IQCF1 CAMTA2 IQCG	1.56e-07	93	81	7	PS50096
Domain	-	DST DSP MACF1	1.56e-06	6	81	3	3.90.1290.10
Domain	Plectin_repeat	DST DSP MACF1	2.72e-06	7	81	3	IPR001101
Domain	Plectin	DST DSP MACF1	2.72e-06	7	81	3	PF00681
Domain	PLEC	DST DSP MACF1	2.72e-06	7	81	3	SM00250
Domain	PH_DOMAIN	EPS8 RASGRF1 TRIO MYO10 GAB4 DAPP1 CIT TIAM2 CYTH4	3.32e-06	279	81	9	PS50003
Domain	PH_domain	EPS8 RASGRF1 TRIO MYO10 GAB4 DAPP1 CIT TIAM2 CYTH4	3.42e-06	280	81	9	IPR001849
Domain	PH	RASGRF1 TRIO MYO10 GAB4 DAPP1 CIT TIAM2 CYTH4	6.73e-06	229	81	8	PF00169
Domain	CH	DST SYNE1 MACF1 DMD UTRN	9.12e-06	65	81	5	SM00033
Domain	CH	DST SYNE1 MACF1 DMD UTRN	1.31e-05	70	81	5	PF00307
Domain	-	DST SYNE1 MACF1 DMD UTRN	1.41e-05	71	81	5	1.10.418.10
Domain	CH	DST SYNE1 MACF1 DMD UTRN	1.61e-05	73	81	5	PS50021
Domain	CH-domain	DST SYNE1 MACF1 DMD UTRN	1.84e-05	75	81	5	IPR001715
Domain	Dystrophin	DMD UTRN	1.86e-05	2	81	2	IPR016344
Domain	Cl_channel-K	CLCNKA CLCNKB	1.86e-05	2	81	2	IPR002250
Domain	PH	RASGRF1 TRIO MYO10 GAB4 DAPP1 CIT TIAM2 CYTH4	2.74e-05	278	81	8	SM00233
Domain	-	EPS8 RASGRF1 TRIO MYO10 GAB4 DAPP1 CIT TIAM2 CYTH4	4.86e-05	391	81	9	2.30.29.30
Domain	PH_dom-like	EPS8 RASGRF1 TRIO MYO10 GAB4 DAPP1 CIT TIAM2 CYTH4	9.38e-05	426	81	9	IPR011993
Domain	GAR	DST MACF1	2.76e-04	6	81	2	PS51460
Domain	EF-hand_dom_typ1	DMD UTRN	2.76e-04	6	81	2	IPR015153
Domain	EF-hand_dom_typ2	DMD UTRN	2.76e-04	6	81	2	IPR015154
Domain	-	DST MACF1	2.76e-04	6	81	2	3.30.920.20
Domain	EF-hand_2	DMD UTRN	2.76e-04	6	81	2	PF09068
Domain	EF-hand_3	DMD UTRN	2.76e-04	6	81	2	PF09069
Domain	GAS_dom	DST MACF1	2.76e-04	6	81	2	IPR003108
Domain	GAS2	DST MACF1	2.76e-04	6	81	2	PF02187
Domain	GAS2	DST MACF1	2.76e-04	6	81	2	SM00243
Domain	GDS_CDC24_CS	RASGRF1 TRIO TIAM2	6.42e-04	39	81	3	IPR001331
Domain	Cl-channel_core	CLCNKA CLCNKB	6.56e-04	9	81	2	IPR014743
Domain	-	CLCNKA CLCNKB	6.56e-04	9	81	2	1.10.3080.10
Domain	Voltage_CLC	CLCNKA CLCNKB	6.56e-04	9	81	2	PF00654
Domain	Cl-channel_volt-gated	CLCNKA CLCNKB	6.56e-04	9	81	2	IPR001807
Domain	Anoctamin	ANO9 ANO8	8.17e-04	10	81	2	PF04547
Domain	Anoctamin	ANO9 ANO8	8.17e-04	10	81	2	IPR007632
Domain	TTL	TTLL2 TTLL4	1.40e-03	13	81	2	PS51221
Domain	TTL/TTLL_fam	TTLL2 TTLL4	1.40e-03	13	81	2	IPR004344
Domain	TTL	TTLL2 TTLL4	1.40e-03	13	81	2	PF03133
Domain	CBS	CLCNKA CLCNKB	2.14e-03	16	81	2	SM00116
Domain	DH_1	RASGRF1 TRIO TIAM2	2.59e-03	63	81	3	PS00741
Domain	ZZ	DMD UTRN	2.72e-03	18	81	2	PF00569
Domain	ZF_ZZ_2	DMD UTRN	2.72e-03	18	81	2	PS50135
Domain	ZF_ZZ_1	DMD UTRN	2.72e-03	18	81	2	PS01357
Domain	Znf_ZZ	DMD UTRN	3.03e-03	19	81	2	IPR000433
Domain	ZnF_ZZ	DMD UTRN	3.03e-03	19	81	2	SM00291
Domain	RhoGEF	RASGRF1 TRIO TIAM2	3.22e-03	68	81	3	SM00325
Domain	CBS_dom	CLCNKA CLCNKB	3.36e-03	20	81	2	IPR000644
Domain	CBS	CLCNKA CLCNKB	3.36e-03	20	81	2	PF00571
Domain	CBS	CLCNKA CLCNKB	3.36e-03	20	81	2	PS51371
Domain	RhoGEF	RASGRF1 TRIO TIAM2	3.49e-03	70	81	3	PF00621
Domain	DH_2	RASGRF1 TRIO TIAM2	3.49e-03	70	81	3	PS50010
Domain	DH-domain	RASGRF1 TRIO TIAM2	3.63e-03	71	81	3	IPR000219
Domain	-	RASGRF1 TRIO TIAM2	3.63e-03	71	81	3	1.20.900.10
Pathway	PID_RAC1_REG_PATHWAY	EPS8 RASGRF1 TRIO TIAM2	2.24e-05	38	62	4	M241
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1 DMD	5.04e-08	4	82	3	8954775
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	DST TRIO SYNE1 MACF1 DMD UTRN TIAM2	7.32e-08	151	82	7	17043677
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DST MYO10 SYNE1 MACF1 MTCL1 BAIAP3	1.51e-07	101	82	6	9872452
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CCND3 RLF TRIO SLC19A1 KCNJ3 LMLN MACF1 ST3GAL1 CHD2 POMT1 TMEM143 TRRAP UTRN BAIAP3 DNAH14 ANO8	3.39e-07	1489	82	16	28611215
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	KMT2D DST DSP SYNE1 PPFIA1 MACF1 DMD	1.41e-06	234	82	7	36243803
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CCND3 KMT2D DST TRIO MYO10 TTLL4 HELZ2 ST3GAL1 TRRAP CIT TIAM2 ANO8 CYTH4	1.83e-06	1105	82	13	35748872
Pubmed	Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	10525423
Pubmed	Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.	CLCNKA CLCNKB	5.49e-06	2	82	2	8544406
Pubmed	Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.	DMD UTRN	5.49e-06	2	82	2	20434517
Pubmed	Plasma lipidomic analysis shows a disease progression signature in mdx mice.	DMD UTRN	5.49e-06	2	82	2	34155298
Pubmed	In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.	DMD UTRN	5.49e-06	2	82	2	28790199
Pubmed	Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.	DMD UTRN	5.49e-06	2	82	2	24466085
Pubmed	The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy.	DMD UTRN	5.49e-06	2	82	2	27110493
Pubmed	Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice.	DMD UTRN	5.49e-06	2	82	2	24781208
Pubmed	Isolation and characterization of a genomic clone from the murine utrophin locus.	DMD UTRN	5.49e-06	2	82	2	8268660
Pubmed	Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	25859846
Pubmed	The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.	CLCNKA CLCNKB	5.49e-06	2	82	2	27335120
Pubmed	G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.	DMD UTRN	5.49e-06	2	82	2	7731967
Pubmed	Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models.	DMD UTRN	5.49e-06	2	82	2	27037492
Pubmed	Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.	CLCNKA CLCNKB	5.49e-06	2	82	2	8812470
Pubmed	Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.	DMD UTRN	5.49e-06	2	82	2	16710609
Pubmed	Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene.	DMD UTRN	5.49e-06	2	82	2	16487708
Pubmed	Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.	DMD UTRN	5.49e-06	2	82	2	30672725
Pubmed	Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.	DMD UTRN	5.49e-06	2	82	2	21677768
Pubmed	Polymorphisms of folate metabolism-related genes and survival of patients with colorectal cancer in the Korean population.	TYMS SLC19A1	5.49e-06	2	82	2	24100087
Pubmed	Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.	DMD UTRN	5.49e-06	2	82	2	7962191
Pubmed	Consequences of the combined deficiency in dystrophin and utrophin on the mechanical properties and myosin composition of some limb and respiratory muscles of the mouse.	DMD UTRN	5.49e-06	2	82	2	9713852
Pubmed	Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.	CLCNKA CLCNKB	5.49e-06	2	82	2	25919862
Pubmed	Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.	CLCNKA CLCNKB	5.49e-06	2	82	2	24863058
Pubmed	Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.	CLCNKA CLCNKB	5.49e-06	2	82	2	9916798
Pubmed	Kidney kinetics and chloride ion pumps.	CLCNKA CLCNKB	5.49e-06	2	82	2	9916791
Pubmed	Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	25607927
Pubmed	Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?	DMD UTRN	5.49e-06	2	82	2	8021701
Pubmed	Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.	DMD UTRN	5.49e-06	2	82	2	26974331
Pubmed	Developmental studies of dystrophin-positive fibers in mdx, and DRP localization.	DMD UTRN	5.49e-06	2	82	2	8433092
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	5.49e-06	2	82	2	11002341
Pubmed	Second-generation compound for the modulation of utrophin in the therapy of DMD.	DMD UTRN	5.49e-06	2	82	2	25935002
Pubmed	Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice.	DMD UTRN	5.49e-06	2	82	2	16024571
Pubmed	Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	28453658
Pubmed	A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.	DMD UTRN	5.49e-06	2	82	2	11801396
Pubmed	Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.	DMD UTRN	5.49e-06	2	82	2	7987307
Pubmed	Utility of dystrophin and utrophin staining in childhood muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	16295426
Pubmed	Comparative analysis of the human dystrophin and utrophin gene structures.	DMD UTRN	5.49e-06	2	82	2	11861579
Pubmed	Distinct mechanical properties in homologous spectrin-like repeats of utrophin.	DMD UTRN	5.49e-06	2	82	2	30914715
Pubmed	Dystrophin is a microtubule-associated protein.	DMD UTRN	5.49e-06	2	82	2	19651889
Pubmed	Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.	DMD UTRN	5.49e-06	2	82	2	9590295
Pubmed	Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.	DMD UTRN	5.49e-06	2	82	2	22284942
Pubmed	Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice.	DMD UTRN	5.49e-06	2	82	2	29879154
Pubmed	Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.	DMD UTRN	5.49e-06	2	82	2	17889902
Pubmed	Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.	DMD UTRN	5.49e-06	2	82	2	12370193
Pubmed	Longitudinal metabolomic analysis of plasma enables modeling disease progression in Duchenne muscular dystrophy mouse models.	DMD UTRN	5.49e-06	2	82	2	32025735
Pubmed	Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice.	DMD UTRN	5.49e-06	2	82	2	27836895
Pubmed	BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.	DMD UTRN	5.49e-06	2	82	2	27750047
Pubmed	Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression.	DMD UTRN	5.49e-06	2	82	2	17967782
Pubmed	Diaphragm rescue alone prevents heart dysfunction in dystrophic mice.	DMD UTRN	5.49e-06	2	82	2	21062902
Pubmed	Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.	DMD UTRN	5.49e-06	2	82	2	35557546
Pubmed	Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.	DMD UTRN	5.49e-06	2	82	2	37626761
Pubmed	Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.	DMD UTRN	5.49e-06	2	82	2	15565469
Pubmed	The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.	DMD UTRN	5.49e-06	2	82	2	26516677
Pubmed	Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.	DMD UTRN	5.49e-06	2	82	2	22209498
Pubmed	A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.	DMD UTRN	5.49e-06	2	82	2	37108685
Pubmed	Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.	DMD UTRN	5.49e-06	2	82	2	10694796
Pubmed	Dystrophin and dystrophin-related protein in the central nervous system of normal controls and Duchenne muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	8171962
Pubmed	Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.	CLCNKA CLCNKB	5.49e-06	2	82	2	38069401
Pubmed	Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice.	DMD UTRN	5.49e-06	2	82	2	27822449
Pubmed	Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model.	DMD UTRN	5.49e-06	2	82	2	33651713
Pubmed	Thermodynamic stability, unfolding kinetics, and aggregation of the N-terminal actin-binding domains of utrophin and dystrophin.	DMD UTRN	5.49e-06	2	82	2	22275054
Pubmed	NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.	DMD UTRN	5.49e-06	2	82	2	27798264
Pubmed	Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice.	DMD UTRN	5.49e-06	2	82	2	31506484
Pubmed	Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	9288752
Pubmed	Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	9288751
Pubmed	Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.	DMD UTRN	5.49e-06	2	82	2	24337461
Pubmed	Combined gene therapy via VEGF and mini-dystrophin synergistically improves pathologies in temporalis muscle of dystrophin/utrophin double knockout mice.	DMD UTRN	5.49e-06	2	82	2	33987645
Pubmed	Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.	DMD UTRN	5.49e-06	2	82	2	11297940
Pubmed	Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice.	DMD UTRN	5.49e-06	2	82	2	29408646
Pubmed	Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.	DMD UTRN	5.49e-06	2	82	2	22388933
Pubmed	Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.	DMD UTRN	5.49e-06	2	82	2	25642938
Pubmed	Activation of non-myogenic mesenchymal stem cells during the disease progression in dystrophic dystrophin/utrophin knockout mice.	DMD UTRN	5.49e-06	2	82	2	25859011
Pubmed	Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.	DMD UTRN	5.49e-06	2	82	2	15703201
Pubmed	Microtubule binding distinguishes dystrophin from utrophin.	DMD UTRN	5.49e-06	2	82	2	24706788
Pubmed	Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.	DMD UTRN	5.49e-06	2	82	2	25941878
Pubmed	Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.	DMD UTRN	5.49e-06	2	82	2	9297964
Pubmed	Dystrophin and utrophin do not play crucial roles in nonmuscle tissues in mice.	DMD UTRN	5.49e-06	2	82	2	10204788
Pubmed	SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.	DMD UTRN	5.49e-06	2	82	2	25652448
Pubmed	A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.	CLCNKA CLCNKB	5.49e-06	2	82	2	20805576
Pubmed	Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.	DMD UTRN	5.49e-06	2	82	2	28785010
Pubmed	The role of proteases in excitation-contraction coupling failure in muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	25298424
Pubmed	Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.	DMD UTRN	5.49e-06	2	82	2	16307000
Pubmed	Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.	DMD UTRN	5.49e-06	2	82	2	21949353
Pubmed	Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.	DMD UTRN	5.49e-06	2	82	2	23097179
Pubmed	rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.	DMD UTRN	5.49e-06	2	82	2	16819550
Pubmed	The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.	DMD UTRN	5.49e-06	2	82	2	15501597
Pubmed	Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.	DMD UTRN	5.49e-06	2	82	2	11257121
Pubmed	Characterization of dystrophin and utrophin diversity in the mouse.	DMD UTRN	5.49e-06	2	82	2	10072426
Pubmed	The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophin.	DMD UTRN	5.49e-06	2	82	2	9625743
Pubmed	Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.	DMD UTRN	5.49e-06	2	82	2	18973234
Pubmed	Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.	DMD UTRN	5.49e-06	2	82	2	12387876
Pubmed	Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.	DMD UTRN	5.49e-06	2	82	2	27881412
Pubmed	Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.	DMD UTRN	5.49e-06	2	82	2	20625423
Pubmed	Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.	DMD UTRN	5.49e-06	2	82	2	29065908
Interaction	PIPSL interactions	PTOV1 PTPN2 TTLL4 HELZ2 PEX10 TIGD5 CMSS1 DNAH14	7.83e-06	252	81	8	int:PIPSL
Cytoband	3p21.2	IQCF2 IQCF1	5.28e-04	19	82	2	3p21.2
Cytoband	12q24	CIT MVK	9.21e-04	25	82	2	12q24
Cytoband	2q33	ADAM23 NIF3L1	1.24e-03	29	82	2	2q33
Cytoband	1p36	CLCNKA CLCNKB	3.23e-03	47	82	2	1p36
GeneFamily	EF-hand domain containing\|Plakins	DST DSP MACF1	1.73e-06	8	58	3	939
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 MYO10 GAB4 DAPP1 TIAM2 CYTH4	5.03e-05	206	58	6	682
GeneFamily	Chloride voltage-gated channels	CLCNKA CLCNKB	4.48e-04	10	58	2	302
GeneFamily	Anoctamins	ANO9 ANO8	4.48e-04	10	58	2	865
GeneFamily	Tubulin tyrosine ligase family	TTLL2 TTLL4	8.98e-04	14	58	2	779
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 TRIO TIAM2	1.24e-03	66	58	3	722
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DMD UTRN	1.50e-03	18	58	2	91
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	GALNT14 DST SYNE1 MACF1 UTRN	7.56e-06	86	82	5	M39248
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	RLF PTPN2 EPS8 DST TRIO MYO10 PPFIA1 MACF1 MTCL1 DMD TRRAP PHIP	1.38e-05	856	82	12	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	PTPN2 EPS8 DST TRIO MYO10 PPFIA1 MTCL1 TRRAP PHIP	1.53e-05	466	82	9	M13522
Coexpression	HOSHIDA_LIVER_CANCER_SURVIVAL_DN	RLF PTPN2 DST KCNJ3 TDO2	2.85e-05	113	82	5	M5451
Coexpression	BUSSLINGER_GASTRIC_X_CELLS	PTOV1 DST DSP KCNJ3 BAIAP3 PHIP	3.06e-05	191	82	6	M40019
Coexpression	GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_DN	EPS8 MTERF1 MYO10 TTLL4 ST3GAL1 MTCL1	3.85e-05	199	82	6	M8385
Coexpression	GSE3982_MAST_CELL_VS_BASOPHIL_DN	CCND3 PTPN2 MTERF1 SYNE1 MACF1 UTRN	3.85e-05	199	82	6	M5439
Coexpression	GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN	EPS8 MAT2B MTERF1 SYNE1 ARL13B SLC28A2	3.96e-05	200	82	6	M5043
Coexpression	GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN	KMT2D CLCNKA HELZ2 SLC28A2 ST3GAL1 UTRN	3.96e-05	200	82	6	M5063
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MXRA5 DST MYO10 COL21A1 SYNE1 MACF1 TDO2	7.99e-08	197	82	7	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	DST TRIO DSP HELZ2 CHD2 UTRN	1.13e-06	183	82	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 SLC35F3 TRIO SYNE1 UTRN DNAH14	1.32e-06	188	82	6	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC22A18AS KCNU1 CLCNKA SLC35F3 CLCNKB FBXO44	1.68e-06	196	82	6	ef650ff106a76c1e926e13c7f002fbc452cc48ae
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DST PDGFRB MYO10 COL21A1 MACF1 TDO2	1.73e-06	197	82	6	31a1852911bda38543916585fda34255fd62a134
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRIQ1 COL21A1 SYNE1 LMLN DMD CCDC191	1.73e-06	197	82	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST PDGFRB MYO10 COL21A1 SYNE1 MACF1	1.84e-06	199	82	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST PDGFRB MYO10 COL21A1 SYNE1 MACF1	1.84e-06	199	82	6	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MXRA5 DST PDGFRB COL21A1 SYNE1 MACF1	1.84e-06	199	82	6	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DST PDGFRB COL21A1 SYNE1 MACF1 TDO2	1.89e-06	200	82	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	DST PDGFRB COL21A1 SYNE1 MACF1 TDO2	1.89e-06	200	82	6	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	Bronchial_Biopsy-Immune-Neutrophils\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	SLC22A18AS SLC19A1 TTLL4 MTBP TIGD5	1.24e-05	162	82	5	985adca17b0c99563feef7910f3da5df31e636b6
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	EPS8 SLC35F3 RASGRF1 DMD BAIAP3	1.48e-05	168	82	5	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DAPP1 HELZ2 PWWP3A UTRN IQCG	1.57e-05	170	82	5	07b561cd9c528bc8444c9385e1de621eee7b697e
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MXRA5 CLCNKB MTBP TIGD5 TIAM2	1.70e-05	173	82	5	b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DST CLCNKA SLC35F3 CLCNKB CYTH4	1.80e-05	175	82	5	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	Control-Myeloid-pDC\|Control / Disease group,lineage and cell class （2021.01.30）	SLC35F3 MTCL1 DMD CRLF2 PROC	1.85e-05	176	82	5	baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 SLC35F3 SYNE1 TDO2 UTRN	1.85e-05	176	82	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GALNT14 SLC35F3 ST3GAL1 DMD DNAH14	1.95e-05	178	82	5	6f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DST CLCNKA SLC35F3 CLCNKB DSP	2.01e-05	179	82	5	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST CLCNKA CLCNKB FBXO44 MYO10	2.06e-05	180	82	5	0b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST CLCNKA SLC35F3 CLCNKB DSP	2.12e-05	181	82	5	40df0afcb6848202da54670e84f22d7c3a515d01
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST CLCNKA SLC35F3 CLCNKB DSP	2.12e-05	181	82	5	2b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST CLCNKA SLC35F3 CLCNKB DSP	2.12e-05	181	82	5	6aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST CLCNKA SLC35F3 CLCNKB DSP	2.12e-05	181	82	5	40d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 LRRIQ1 SLC35F3 KCNJ3 TDO2	2.41e-05	186	82	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRIQ1 SLC35F3 RASGRF1 PROC IQCG	2.41e-05	186	82	5	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	10x5'v1-week_14-16-Myeloid_DC-DC-pDC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PTPN2 SLC35F3 TMIGD2 CYTH4 PROC	2.48e-05	187	82	5	bf64a6ef5062ec9a0f7095e8c97ce66bfc3bf179
ToppCell	3'_v3-blood-Myeloid_Dendritic\|blood / Manually curated celltypes from each tissue	DST SLC35F3 DAPP1 DMD PROC	2.54e-05	188	82	5	239a2162a21d3339da7c1884ab76286346fbf97f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRIQ1 CLCNKA SLC35F3 CLCNKB CCDC191	2.60e-05	189	82	5	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCND3 GALNT14 LRRIQ1 SYNE1 DNAH14	2.67e-05	190	82	5	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	remission-B_memory\|World / disease stage, cell group and cell class	RASGRF1 DAPP1 CCDC191 BAIAP3 TIAM2	2.67e-05	190	82	5	c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDGFRB MYO10 KCNJ3 SYNE1 TMIGD2	2.67e-05	190	82	5	600b9674197f743dea1d19d3df0fc993b6e6aa25
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CLCNKA DSP KCNJ3 BAIAP3 PROC	2.67e-05	190	82	5	b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRIQ1 SLC35F3 RASGRF1 DSP PROC	2.74e-05	191	82	5	b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 PDGFRB COL21A1 DMD UTRN	2.74e-05	191	82	5	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDGFRB MYO10 KCNJ3 SYNE1 TMIGD2	2.81e-05	192	82	5	c5f77c2103841505d13e09173549811312ef2f01
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDGFRB MYO10 KCNJ3 SYNE1 TMIGD2	2.81e-05	192	82	5	e981162f387a31111c0ae8355dbe9db5785c4838
ToppCell	10x3'2.3-week_14-16-Myeloid_DC-DC-pDC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PTPN2 SLC35F3 TMIGD2 CYTH4 PROC	2.88e-05	193	82	5	2c35aadc397e7e365c3daf8017ae1d3bd045f305
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TYMS GALNT14 EPS8 MXRA5 PDGFRB	2.95e-05	194	82	5	78dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCell	368C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DST MYO10 COL21A1 MACF1 TDO2	2.95e-05	194	82	5	d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRIQ1 COL21A1 SYNE1 CCDC191 IQCG	2.95e-05	194	82	5	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	368C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DST MYO10 COL21A1 MACF1 TDO2	2.95e-05	194	82	5	e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 PDGFRB COL21A1 DMD UTRN	3.10e-05	196	82	5	b8759e6231e0254797d6c30930407b79440c57bb
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC22A18AS KCNU1 CLCNKA SLC35F3 CLCNKB	3.10e-05	196	82	5	72b6a68ee760599ea86cd2d712bfd17b7b4ee417
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DSP ST3GAL1 MTCL1 UTRN PHIP	3.18e-05	197	82	5	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	BAL-Mild-cDC_10\|Mild / Compartment, Disease Groups and Clusters	ANO9 DAPP1 DMD CRLF2 TIAM2	3.18e-05	197	82	5	c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 PDGFRB SYNE1 DMD UTRN	3.18e-05	197	82	5	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DST MYO10 COL21A1 MACF1 TDO2	3.18e-05	197	82	5	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.25e-05	198	82	5	0e918e9db9b884f5328d438e90efe065e27266ee
ToppCell	Sepsis-URO-Others\|URO / Disease, condition lineage and cell class	TYMS SLC35F3 TMIGD2 NIF3L1 MTBP	3.25e-05	198	82	5	6caab5266da666cfbe92ac1ace26ad2004e5aa09
ToppCell	Sepsis-URO-Others-RBC\|URO / Disease, condition lineage and cell class	TYMS SLC35F3 TMIGD2 NIF3L1 MTBP	3.25e-05	198	82	5	d35e9d0952b3f7cd5d0d1a69bad2ae81af8eed50
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.25e-05	198	82	5	ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.25e-05	198	82	5	fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.25e-05	198	82	5	1ef3a6bd681c223eed58300348adfef89df5563c
ToppCell	15-Distal-Mesenchymal-Mesenchyme_RSPO2+\|Distal / Age, Tissue, Lineage and Cell class	TYMS DST COL21A1 MACF1 TDO2	3.25e-05	198	82	5	e87d1fe2befbd32b0c723ab43b9de95495ea3ee3
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.33e-05	199	82	5	4820f5bcd7bc34c2ebf6a3422cc8eb383a3b5a4e
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.33e-05	199	82	5	eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.33e-05	199	82	5	10c8729b779073c3bf808e85958d59147f0be5c5
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EPS8 MXRA5 PDGFRB COL21A1 TDO2	3.33e-05	199	82	5	95d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.33e-05	199	82	5	867fd292f3879982422e840e087bfdb3b21a8715
ToppCell	Control-Lymphoid_T/NK-NK\|Control / Disease group, lineage and cell class	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.33e-05	199	82	5	94b2693a8378b9b2c58c6aebb2c6658d75b2e3de
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MXRA5 PDGFRB COL21A1 SYNE1 TDO2	3.33e-05	199	82	5	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	MXRA5 DST PDGFRB COL21A1 MACF1	3.33e-05	199	82	5	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	MXRA5 DST PDGFRB COL21A1 MACF1	3.33e-05	199	82	5	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	Neuronal-Excitatory-eF(C1QL3)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GALNT14 SLC35F3 ST3GAL1 DMD DNAH14	3.41e-05	200	82	5	7668ae7ed550583ab59e419c5c9bb9f2d7e8e0d5
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	PDGFRB COL21A1 SYNE1 MACF1 TDO2	3.41e-05	200	82	5	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DST PDGFRB COL21A1 SYNE1 MACF1	3.41e-05	200	82	5	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	Neuronal-Excitatory-eF(C1QL3)----L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GALNT14 SLC35F3 ST3GAL1 DMD DNAH14	3.41e-05	200	82	5	44f0278cb0e4ffcda4af3719d7f5819a10929b9f
ToppCell	wk_20-22-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DST MYO10 COL21A1 MACF1 TDO2	3.41e-05	200	82	5	0ed49c2177b58269ff7653db6be7d68633a5d34a
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DST PDGFRB COL21A1 SYNE1 MACF1	3.41e-05	200	82	5	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Control-Control-Lymphocyte-T/NK-NK\|Control / Disease, condition lineage and cell class	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.41e-05	200	82	5	c64c27dbf4df42ca2ad2bd94b50fab87b4050ef3
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HELZ2 MACF1 CHD2 UTRN PHIP	3.41e-05	200	82	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Neuronal-Excitatory-eF(C1QL3)---\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GALNT14 SLC35F3 ST3GAL1 DMD DNAH14	3.41e-05	200	82	5	23da7790e09575b2ca909ed16806b44223bf1017
ToppCell	mild-NK\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.41e-05	200	82	5	a11fb1d7e124c352eb73fea0e0ec0fed577c97f7
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST PDGFRB COL21A1 SYNE1 MACF1	3.41e-05	200	82	5	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated\|COVID-19_Severe / Disease, condition lineage and cell class	PDGFRB SYNE1 TMIGD2 MACF1 UTRN	3.41e-05	200	82	5	6a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	DST PDGFRB MYO10 COL21A1 MACF1	3.41e-05	200	82	5	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	PDGFRB COL21A1 SYNE1 MACF1 TDO2	3.41e-05	200	82	5	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST PDGFRB COL21A1 SYNE1 MACF1	3.41e-05	200	82	5	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	Neuronal-Excitatory-eF(C1QL3)-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GALNT14 SLC35F3 ST3GAL1 DMD DNAH14	3.41e-05	200	82	5	91f3df1c5a661ff703835f58a35cee93f18eb15c
ToppCell	Neuronal-Excitatory-eF(C1QL3)--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GALNT14 SLC35F3 ST3GAL1 DMD DNAH14	3.41e-05	200	82	5	2e2b1d252972b702ade25526ec8461bf613d81b0
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SYNE1 MACF1 CHD2 UTRN	1.13e-04	135	82	4	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 SLC35F3 ADAM23 KCNJ3	1.53e-04	146	82	4	e887e9de895fd453faa703997ef372cc6410fc49
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 MGAT2 RADX TIGD5	1.57e-04	147	82	4	f703cb0330304799d16e457215269c7732c9d5d5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM23 COL21A1 DAPP1 TDO2	2.17e-04	160	82	4	14dfa519e68bab4bce890ddb66fa7763f18d9f19
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM23 COL21A1 DAPP1 TDO2	2.17e-04	160	82	4	839bbdfd4e4c7b48260c8bfb7670378634405e1d
ToppCell	IPF-Epithelial-Ionocyte\|IPF / Disease state, Lineage and Cell class	CLCNKA SLC35F3 CLCNKB DSP	2.17e-04	160	82	4	d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM23 COL21A1 DAPP1 TDO2	2.17e-04	160	82	4	5b7789d4668ed7732babedc32d812233b430e0bd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM23 COL21A1 DAPP1 TDO2	2.17e-04	160	82	4	bba1486faaad5299e10f4fe17c6d149c28dc2560
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells-pDC\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC35F3 DAPP1 FCHO1 CYTH4	2.17e-04	160	82	4	dee756a2dc9725520d439e7273c489c2284015d8
ToppCell	356C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	SLC35F3 TMIGD2 MTCL1 PROC	2.33e-04	163	82	4	ae9c5eb19657ea94b7f2357cbc8679acd697b8fe
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	DST BAIAP3 CRLF2 DNAH14	2.33e-04	163	82	4	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KMT2D KCNJ3 CIT ANO8	2.39e-04	164	82	4	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TMEM143 CCDC191 ANO8 PROC	2.39e-04	164	82	4	1aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell	356C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SLC35F3 TMIGD2 MTCL1 PROC	2.39e-04	164	82	4	fed26f4ac36a2b0722bc7b9f91659c5e0cf4d53a
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KMT2D KCNJ3 CIT ANO8	2.39e-04	164	82	4	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CLCNKA SLC35F3 CLCNKB PWWP3A	2.44e-04	165	82	4	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	EPS8 PDGFRB DMD UTRN	2.44e-04	165	82	4	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 DAPP1 CRLF2 CYTH4	2.61e-04	168	82	4	2c996d09b6a8ccd3c708146eca310b02eafff425
Computational	Genes upregulated in subsets of cells of a given type within various tumors	MXRA5 DST TRIO SYNE1 MACF1	3.55e-06	50	51	5	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 MACF1 CHD2 UTRN	8.14e-05	49	51	4	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Drug	plakin	DST DSP SYNE1 MACF1 DMD UTRN	4.74e-07	82	81	6	CID000018752
Drug	lometrexol	TYMS SLC19A1 SYNE1 MVK	1.78e-06	25	81	4	CID000001773
Drug	Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; PC3; HT_HG-U133A	TRIO ADAM23 COL21A1 VPS16 TMEM143 CYTH4 PROC	6.39e-06	196	81	7	5058_UP
Drug	NSC-81150	TYMS SLC28A2 CIT	1.21e-05	13	81	3	CID000416721
Drug	5-enolpyruvoylshikimate-3-phosphate	PTPN2 EPS8 CLCNKA CLCNKB PDGFRB	1.25e-05	84	81	5	CID000000082
Drug	thiophenone	SYNE1 TDO2	1.25e-05	2	81	2	CID009548690
Drug	tert-butyl-4-(prop-2-ynylamino)benzoate	TYMS SLC19A1	1.25e-05	2	81	2	CID010082621
Drug	BGC638	TYMS SLC19A1	1.25e-05	2	81	2	ctd:C504663
Drug	Compound 1-4	TYMS PTPN2 PDGFRB SYNE1	1.81e-05	44	81	4	CID005311149
Drug	AzddU	TYMS SYNE1 CIT	2.85e-05	17	81	3	CID000055262
Drug	Gly-Met	TYMS SLC28A2 CIT	2.85e-05	17	81	3	CID000096757
Drug	diethyl N-(4-aminobenzoyl)-L-glutamate	TYMS SYNE1	3.74e-05	3	81	2	CID000073002
Drug	10-propargylaminopterin	TYMS SYNE1	3.74e-05	3	81	2	CID000100093
Drug	dipropargyl	TYMS SYNE1	3.74e-05	3	81	2	CID000069402
Drug	BGC945	TYMS SLC19A1	3.74e-05	3	81	2	ctd:C504662
Drug	Wang resin	TYMS DST	3.74e-05	3	81	2	CID000070043
Drug	R4--a	DMD UTRN PROC	4.73e-05	20	81	3	CID005289251
Drug	Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; HL60; HT_HG-U133A	KMT2D RASGRF1 TRIO PDGFRB BAIAP3 PROC	6.96e-05	195	81	6	3028_UP
Drug	Levonordefrin [829-74-3]; Up 200; 21.8uM; MCF7; HT_HG-U133A	PIGN MGAT2 RASGRF1 UTRN BAIAP3 PROC	7.16e-05	196	81	6	7208_UP
Drug	Pentolinium bitartrate [52-62-0]; Down 200; 7.4uM; HL60; HT_HG-U133A	MGAT2 SLC19A1 MACF1 POMT1 UTRN CYTH4	7.36e-05	197	81	6	2343_DN
Drug	IDETA	DMD UTRN	7.47e-05	4	81	2	CID003036201
Drug	isofolic acid	TYMS SYNE1	7.47e-05	4	81	2	CID000191247
Disease	Bartter disease type 4B	CLCNKA CLCNKB	7.26e-06	2	80	2	cv:C4310805
Disease	BARTTER SYNDROME, TYPE 4B	CLCNKA CLCNKB	7.26e-06	2	80	2	C2751312
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	7.26e-06	2	80	2	C4310805
Disease	Bartter disease type 3 (implicated_via_orthology)	CLCNKA CLCNKB	7.26e-06	2	80	2	DOID:0110144 (implicated_via_orthology)
Disease	Bartter disease type 4b (is_implicated_in)	CLCNKA CLCNKB	7.26e-06	2	80	2	DOID:0110146 (is_implicated_in)
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	7.26e-06	2	80	2	613090
Disease	Bartter disease (implicated_via_orthology)	CLCNKA CLCNKB	7.26e-06	2	80	2	DOID:445 (implicated_via_orthology)
Disease	Bartter syndrome	CLCNKA CLCNKB	1.08e-04	6	80	2	cv:C0004775
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	KCNU1 DMD UTRN	1.28e-04	36	80	3	DOID:11723 (implicated_via_orthology)
Disease	Intellectual Disability	TRIO PDGFRB SYNE1 ARL13B MACF1 TRRAP PHIP	2.14e-04	447	80	7	C3714756
Disease	nephrogenic diabetes insipidus (implicated_via_orthology)	CLCNKA CLCNKB	3.22e-04	10	80	2	DOID:12387 (implicated_via_orthology)
Disease	vital capacity	DST LRRIQ1 DSP COL21A1 SYNE1 MTCL1 CMSS1 UTRN TIAM2 MVK PROC	4.93e-04	1236	80	11	EFO_0004312
Disease	Lymphoma, Large-Cell, Follicular	TYMS KMT2D	7.45e-04	15	80	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	TYMS KMT2D	7.45e-04	15	80	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	TYMS KMT2D	7.45e-04	15	80	2	C0079758
Disease	cleft lip (is_implicated_in)	SLC19A1 POMT1	7.45e-04	15	80	2	DOID:9296 (is_implicated_in)
Disease	Lymphoma, Follicular, Grade 2	TYMS KMT2D	7.45e-04	15	80	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	TYMS KMT2D	7.45e-04	15	80	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	TYMS KMT2D	7.45e-04	15	80	2	C1956130
Disease	muscular dystrophy (is_implicated_in)	SYNE1 POMT1	9.61e-04	17	80	2	DOID:9884 (is_implicated_in)
Disease	Lymphoma, Follicular	TYMS KMT2D	1.34e-03	20	80	2	C0024301
Disease	urate measurement, bone density	ZNF695 SYNE1 HELZ2 TDO2 UTRN DNAH14 TIAM2	1.46e-03	619	80	7	EFO_0003923, EFO_0004531
Disease	muscular dystrophy (implicated_via_orthology)	DMD UTRN	1.47e-03	21	80	2	DOID:9884 (implicated_via_orthology)
Disease	peripheral arterial disease, traffic air pollution measurement	KCNJ3 MACF1 MTCL1 UTRN	1.94e-03	194	80	4	EFO_0004265, EFO_0007908

Protein segments in the cluster

Peptide	Gene	Start	Entry
QWPFLSELQWLKRRK	ADAM23	271	O75077
QLRDWEVLVLGKLKW	CCND3	136	P30281
KLWFQVLRDQAKWRL	BAIAP3	701	O94812
REWLKWSREELLGQL	CAMTA2	171	O94983
KFLVFDWNWRDQKLR	CMSS1	231	Q9BQ75
WFKRWREPVRKVTLL	ARL13B	11	Q3SXY8
DFLLQRKRLWLWASE	SLC22A18AS	31	Q8N1D0
GRVKTWKRRWFILTD	CYTH4	271	Q9UIA0
WTEDRWVLLQDILLK	DMD	546	P11532
LWATVFLEIWKRQRA	ANO9	276	A1A5B4
LLEKERQWEAWRSVL	CIT	1036	O14578
NVIWSTLFLEEWKRR	ANO8	291	Q9HCE9
LLELKSVIKLQAWWR	IQCG	391	Q9H095
WWRLILSKILKKRRQ	IQCF1	101	Q8N6M8
RQEWERQKKEFLWRI	MTCL1	1256	Q9Y4B5
ERKRKRWLYWQPILT	PTPN2	376	P17706
LAGARKWLEWRKEVE	PEX10	36	O60683
ISDRWESQLWREKKF	RADX	676	Q6NSI4
AATWNLEEKRLTWRL	FCHO1	806	O14526
KESLWPFLIDKRWRQ	MAT2B	316	Q9NZL9
WKLHFVWERVKILRD	MGAT2	236	Q10469
KWQQVWLLALERRRK	DST	7151	Q03001
WSDKVVRKVERLWDV	LMLN	316	Q96KR4
WQWSRELKLRLKKLR	C9orf131	781	Q5VYM1
LWRDLIDLVTLWKRK	FBXO44	36	Q9H4M3
SWKRRWCVLKDETFL	MYO10	1191	Q9HD67
KDVLVWSNDRVIRWI	PPFIA1	1046	Q13136
ILLIFRLIWRSVKKW	KCNU1	41	A8MYU2
RLIWRSVKKWQIIKG	KCNU1	46	A8MYU2
LLLLSLWKLWRVKKF	CRLF2	246	Q9HC73
RRLAWIKSFKPWLEI	LRRIQ1	741	Q96JM4
WQQVWLLALERQRKL	MACF1	6996	Q9UPN3
KLLAWSGVLEWQEKR	PTOV1	91	Q86YD1
LWITVLLFFWVTKRK	GALNT14	16	Q96FL9
RRWEKWELDLDIKEV	PROC	271	P04070
LKALRWKDSWDILIR	POMT1	731	Q9Y6A1
LKEPTWKQWREFLVK	BFAR	321	Q9NZS9
IKLWRRNLWIFVSKF	CHD2	1526	O14647
PEKKLRLFAWRKRWF	GAB4	51	Q2WGN9
RWQRIDKQIDFRLWD	DSP	866	P15924
SDWKIQLKVLRAWRD	CCDC191	351	Q8NCU4
EADEWIKILRWKLSQ	DAPP1	246	Q9UN19
TQRFKVKKIWDLWRI	COL21A1	286	Q96P44
VKKIWDLWRILTIDG	COL21A1	291	Q96P44
TLRKKLWEAQEEWKR	DNAH14	931	Q0VDD8
WWRMTLSRVLEKKRQ	IQCF2	76	Q8IXL9
DILEILDDRKQWWKV	EPS8	556	Q12929
ALWKQLLELVELQRW	HELZ2	1826	Q9BYK8
KELWRGKIQIWERKF	MTBP	236	Q96DY7
WQKKPRYEIRWKVIE	PDGFRB	556	P09619
WEKRLWPAKVLARTA	PWWP3A	11	Q2TAK8
WNRLLMSLEELIKWL	UTRN	2561	P46939
WDIRNLLIWIKKNLL	URM1	36	Q9BTM9
RLKIEETWRLWQKFL	SYNE1	7991	Q8NF91
LWFKQILWELDSVRE	TDO2	81	P48775
VIREWKWEKPYLKNR	ODAD3	131	A5D8V7
DTYRWWLRLQREKKP	ST3GAL1	96	Q11201
VWVWDIQKLRLFAVL	WRAP73	356	Q9P2S5
KRITWNTWKERLVIR	NIF3L1	101	Q9GZT8
WLCRRKWKTIIQDYI	RASGRF1	216	Q13972
EEWDVWLIKLLTRLK	SLC35F3	376	Q8IY50
KPFENSRLRLWTKWV	SLC28A2	136	O43868
LEWLKQKVFRLGEDW	CLCNKA	36	P51800
LEWLKQKLFRLGEDW	CLCNKB	36	P51801
KLRLRNDWEIVGEWK	ZNF695	121	Q8IW36
AWERLRVKWTKDGAI	TMIGD2	51	Q96BF3
VWKWRDERLDLQWSL	WDR61	46	Q9GZS3
KLELVARRKWKQYWV	TIAM2	526	Q8IVF5
IWQFKRREWKSILLD	PHIP	391	Q8WWQ0
SRWLRSEVENWLLAK	TMEM143	391	Q96AN5
WELTLFWSKLQRRID	RLF	316	Q13129
RWTKEDLELINKWAF	MVK	176	Q03426
FVKIRWARWSKLLIA	SLC19A1	326	P41440
ARDFRIPDKRLWWLK	VPS16	716	Q9H269
TKRVFWKGVLEELLW	TYMS	76	P04818
PENLSKRWDLWRKIV	MTERF1	136	Q99551
KRWDLWRKIVTSDLE	MTERF1	141	Q99551
LRSWDVDDLLLWKKI	TTLL2	331	Q9BWV7
LKEWRLENWKRLDVN	PIGN	306	O95427
CEEFWSRLRKLNWKR	RWDD2B	236	P57060
WLKDEPKLRWFLEQL	TIGD5	91	Q53EQ6
VEKLPWEQRKLLRWK	TTLL4	596	Q14679
EKTWVQLFPRLWKIL	TRRAP	2626	Q9Y4A5
KELWTWLEELQKELL	TRIO	681	O75962
KWKGVRWKRLRLLLT	KMT2D	4981	O14686
VDLKWRWNLFIFILT	KCNJ3	76	P48549
RWFLEWDAKSRGILK	MXRA5	226	Q9NR99